CN103705614B - Traditional Chinese medicine for treating herpes zoster - Google Patents

Traditional Chinese medicine for treating herpes zoster Download PDF

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Publication number
CN103705614B
CN103705614B CN201310685666.0A CN201310685666A CN103705614B CN 103705614 B CN103705614 B CN 103705614B CN 201310685666 A CN201310685666 A CN 201310685666A CN 103705614 B CN103705614 B CN 103705614B
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herpes zoster
chinese medicine
herba
traditional chinese
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CN103705614A (en
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刘艳
李慧
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Jie Weiwei
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Abstract

The invention relates to a traditional Chinese medicine for treating herpes zoster, which is prepared from the following raw material medicines in parts by weight: 4 parts of alderleaf sida leaf, 2 parts of euphorbia lunulata, 5 parts of radix pulsatillae, 6 parts of caulis spatholobi, 4 parts of decumbent bugle herb, 3 parts of rauvolfia latifrons, 4 parts of levisticum officinale, 3 parts of sandalwood, 3 parts of herba acalyphae, 5 parts of flos hibisci mutabilis, 3 parts of folium eriobotryae, 2 parts of fructus trichosanthis, 1 part of akebia stem, 4 parts of cortex phellodendri, 2 parts of subprostrate sophora and 3 parts of Wannianbai. Clinical experiments prove that the traditional Chinese medicine provided by the invention can safely and effectively treat herpes zoster.

Description

A kind of Chinese medicine for the treatment of herpes zoster
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine for the treatment of herpes zoster.
Background technology
Herpes zoster is the actute infection dermatoses caused by varicella zoster virus.After infected to this viral child without immunity, there is chickenpox.Become carrier after some patients is infected and symptom do not occur.Because virus has neurotropism, can hide for a long time in the neuron of spinal nerves posterior root ganglion after infection, when lower for the resistance or tired, infection, flu, virus can regrow breeding, and move to skin along nerve fiber, make the nerve of being invaded and skin produce strong inflammation.Current herpes zoster mainly applies physical therapy and antibiotic, and spend high, curative effect is low, and side effect is large.Therefore the Chinese medicine researching and developing a kind of safe and effective treatment herpes zoster very has value for clinical application.
Involved by Chinese medicine of the present invention, the present Research of medical material is as follows:
Folium sidae alnifoliae: this product is the leaf of the little Radix Bupleuri of Malvaceae plant.[nature and flavor] are bitter; Pungent; Cold nature.[return through] heart channel.[function cures mainly] clearing away heat-damp and promoting diuresis; Removing toxic substances and promoting subsidence of swelling.Main damp-heat dysentery; Jaundice; Laryngopharynx swelling and pain; Carbuncle sore tumefacting virus; Bee venom sting.[usage and dosage] 30-60g.
Herba euphorbiae lunulatae: this product is the herb of Euphorbiaceae euphorbia Herba euphorbiae lunulatae Euphorbia lunulata Bunge.Nature and flavor] bitter in the mouth; Cold nature; Poisonous.[return through] lung; Liver Channel.[function cures mainly] antitussive; Eliminate the phlegm; Eliminating stagnation; Relieve oedema or abdominal distension through diuresis or purgation; Draw out pus by applying a plaster to the affected part; Parasite killing.Main phlegm retention cough with asthma; Edema; Scrofula; Scabies; Innominate toxic swelling.[usage and dosage] 3-9g.
The Radix Pulsatillae: this product is the dry root of ranunculaceae plant Radix Pulsatillae Pulsatilla chinensis (Bge.) Regel.[nature and flavor] are bitter, cold.[return through] returns stomach, large intestine channel.[function cures mainly] heat-clearing and toxic substances removing, eliminating pathogenic heat from blood to cure dysentery.For toxic-heat and blood stasis, pudendal pruritus leukorrhagia, amebic dysentery.[usage and dosage] 9 ~ 15g.
Caulis Spatholobi: this product is the dry rattan of leguminous plant spatholobus suberectus (Caulis Sargentodoxae, Radix seu Caulis Verntilaginis Leiocarpae, SANYE Caulis Spatholobi, nine layers of wind) Spatholobus suberectus Dunn.[nature and flavor] are bitter, sweet, temperature.[return through] returns liver, kidney channel.[function cures mainly] enriches blood, and invigorates blood circulation, dredging collateral.For menoxenia, blood deficiency and yellow complexion, paralysis and numbness, rheumatic arthralgia.[usage and dosage] 9 ~ 15g.
Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.): the herb of Labiatae bugle Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) Ajuga decumbens Thunb..[nature and flavor] bitter in the mouth; Cold in nature.[function cures mainly] heat-clearing and toxic substances removing; Removing heat from blood is subsided a swelling.Main laryngopharynx swelling and pain; Lung-heat is spat blood; Treating swelling and pain by traumatic injury.[usage and dosage] takes orally: decoct soup, 15-30g.
Rheumatism wood: this product is Apocynaceae rheumatism wood Rauvolfia latifrons Tsiang, is used as medicine with root, stem.[function cures mainly] expelling wind and activating blood circulation.Cure mainly rheumatalgia; External can synthetism.
Radix Levistici Officinalis: this product is the root of Umbelliferae bar thing Radix Levistici Officinalis.[nature and flavor] acrid in the mouth; Micro-sweet; Slightly warm in nature.[function cures mainly] promoting blood flow to regulate menstruation; Diuresis.Main warp closes; Dysmenorrhea; Dizzy; Headache; Limb fiber crops; Edema.[usage and dosage] 6-15g.
Lignum Santali Albi: this product is the heartwood of Santalaceae Lignum Santali Albi platymiscium Lignum Santali Albi Santalum album L. trunk.[nature and flavor] are pungent, temperature.[return through] returns spleen, stomach, the heart, lung meridian.[function cures mainly] circulation of qi promoting warming middle-JIAO, appetizing pain relieving.For QI stagnated by cold, chest pain, stomachache, stomachache lack of appetite; Coronary heart disease, angina pectoris.[usage and dosage] 2 ~ 5g.
Herba Acalyphae: this product is the herb of euphorbia plant Herba Acalyphae.[nature and flavor] are bitter; Puckery; Cool.[return through] heart; Lung; Large intestine; Small intestine meridian.[function cures mainly] clearing away heat-damp and promoting diuresis; Removing pathogenic heat from blood and toxic substance from the body; Removing food stagnancy.Main dysentery; Have loose bowels; Spit blood; Epistaxis; Hematuria; Metrorrhagia; Infantile malnutrition; Carbuncle furuncle infections; Skin eczema.[usage and dosage 10-15g.
Flos Hibisci Mutabilis: be the flower of Malvaceae plant Hibisci Mutabilis.[nature and flavor] are pungent; Micro-hardship; Cool.[return through] lung; The heart; Liver Channel.[function cures mainly] heat-clearing and toxic substances removing; Cooling blood for hemostasis; Detumescence and apocenosis.Main cough due to lung-heat; Spit blood; Conjunctival congestion and swelling pain; Metrorrhagia; Leucorrhea; Diarrhoea; Stomachache; Carbuncle; Furuncle; Venom; Burn due to hot liquid or fire; Traumatic injury.[usage and dosage] 9-15g.
Folium Eriobotryae: this product is the dried leaves of rosaceous plant Folium Eriobotryae Eriobotrya japonica (Thunb.) Lindl..[nature and flavor] are bitter, are slightly cold.[return through] attaches to the lung and stomach meridians.[function cures mainly] clearing away lung-heat to relieve cough, stopping nausea and vomiting by lowering the adverse flow of QI.For cough due to lung-heat, QI rising in reverse order dyspnea with rapid respiration, gastric heat vomiting, dysphoria with smothery sensation is thirsty.[usage and dosage] 6 ~ 9g.
Fructus Trichosanthis: this product is the dry mature fruit of cucurbitaceous plant Fructus Trichosanthis Trichosanthes kirilowii Maxim. or trichosanthes rosthornii Harms Trichosan-thes rosthornii Harms.[nature and flavor] sweet, micro-hardship, cold.[return through] returns lung, stomach, large intestine channel.[function cures mainly] clearing away heat and eliminating phlegm, relieving stuffiness of the chest by dispersing aggregation of pathogens, moisturizes laxation.For cough due to lung-heat, the turbid Huang of expectorant is thick, obstruction of qi in the chest and cardialgia, blocked-up chest feeling of fullness, acute mastitis, lung abscess, and acute appendicitis swells and ache, constipation.[usage and dosage] 9 ~ 15g.
Caulis Akebiae: this product is Teng's stem of plants of Lardizabalaceae Caulis Akebiae, threeleaf akebia or Caulis Akebiae.[nature and flavor] are bitter; Cold in nature.[return through] heart; Spleen; Kidney; Small intestinal; Urinary bladder channel.[function cures mainly] clearing away heat and promoting diuresis; Blood circulation and channel invigorating.Main red urine is red; Stranguria with turbid discharge; Edema; Irritable feverish sensation in the chest; Larynx larynx pain; Aphtha of the mouth and tongue; Rheumatic arthralgia; Galactostasis; Amenorrhea; Dysmenorrhea.[usage and dosage] 3-6g.
Cortex Phellodendri: this product is the dry bark of rutaceae wampee Phellodendron chinense Schneid. or Cortex Phellodendri Phellodendron amurense Rupr..[nature and flavor] are bitter, cold.[return through] returns kidney, urinary bladder channel.[function cures mainly] heat clearing and damp drying, pathogenic fire purging removes steams, detoxification sore treatment.For damp-heat dysentery, jaundice, leukorrhagia, pyretic stranguria, beriberi, flaccidity { is warded off }, hectic fever due to YIN-deficiency consumptive fever, night sweat, seminal emission, sore swollen toxin, eczema pruritus.Stir-baked CORTEX PHELLODENDRI with salt solution nourishing YIN to lower pathogenic fire.For hyperactivity of fire caused by deficiency of YIN, night sweat hectic fever due to YIN-deficiency.[usage and dosage] 3 ~ 12g
Radix Sophorae Tonkinensis: this product is pulse family anil HUAMU blue Indigofera Kirilowii Maxim. ex Palibin, is used as medicine with root.[nature and flavor] are bitter, cold.[function cures mainly] heat-clearing and toxic substances removing, reducing swelling and alleviating pain, relieving constipation.For laryngopharynx swelling and pain, cough due to lung-heat, jaundice, constipation with heat retention; Swelling and pain of hemorrhoid is controlled in external, snake bite and insect sting.
Wan Nianbai: be fern Aspleniaceae spleen wort tiger tail Asplenium trchomanes L., with all herbal medicine.[nature and flavor] are bitter, sweet, cool.[function cures mainly] heat-clearing and toxic substances removing, checking hyperfunction of the liver for relieving convulsion, pain relieving.For hepatitis, infantile malnutrition, toothache, venom.[usage and dosage] 2 ~ 5g.
Summary of the invention
The present invention aims to provide a kind of Chinese medicine for the treatment of herpes zoster, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective healing herpes zoster.
In order to achieve the above object, the present invention is by the following technical solutions:
A kind of Chinese medicine for the treatment of herpes zoster, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Folium sidae alnifoliae 4 parts, Herba euphorbiae lunulatae 2 parts, the Radix Pulsatillae 5 parts, Caulis Spatholobi 6 parts, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 4 parts, 3 parts, rheumatism wood, Radix Levistici Officinalis 4 parts, 3 parts, Lignum Santali Albi, Herba Acalyphae 3 parts, Flos Hibisci Mutabilis 5 parts, Folium Eriobotryae 3 parts, Fructus Trichosanthis 2 parts, Caulis Akebiae 1 part, Cortex Phellodendri 4 parts, Radix Sophorae Tonkinensis 2 parts, Wan Nianbai 3 parts.
Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:
1, physical data
Inventor collects 50 routine Patients with Herpes Zosters between in April ,-2013 in January, 2010 altogether, age 18-46 year, course of disease 1-30 days.Be divided at random: treatment group 25 example, matched group 25 example.Two groups of data there was no significant differences such as sex, age, have comparability.
2, test method
2.1 Therapeutic Method
Matched group takes cefclidin, by specification use, 10 days courses for the treatment of.
The capsule that the oral the present invention for the treatment of group obtains according to specific embodiment 1, every day 2 times.10 days courses for the treatment of.
2.2 observation items: before and after experiment, to pain, lump, suppuration face size, body temperature and blood parameters chemical examination record.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
Recovery from illness: clinical symptoms all disappears, test chamber inspection is normal, has no recurrence in half a year.Take a turn for the better: clinical symptom relief, lab testing improvement or normal.Invalid: clinical symptoms, lab testing are without being clearly better or increasing the weight of.
3.2 treatment statistical results are in table 1.
Table 1 liang group comparitive study
Group n Recovery from illness Take a turn for the better Invalid Untoward reaction example Total effective rate (%)
Treatment group 25 20 3 5 1(4%) 80%
Matched group 25 3 6 16 22(88%) 36%
Visible, the medicine that the present invention obtains can safe and effective treatment herpes zoster.
Detailed description of the invention
In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Specific embodiment 1
Take Folium sidae alnifoliae 4g, Herba euphorbiae lunulatae 2g, Radix Pulsatillae 5g, Caulis Spatholobi 6g, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 4g, rheumatism wood 3g, Radix Levistici Officinalis 4g, Lignum Santali Albi 3g, Herba Acalyphae 3g, Flos Hibisci Mutabilis 5g, Folium Eriobotryae 3g, Fructus Trichosanthis 2g, Caulis Akebiae 1g, Cortex Phellodendri 4g, Radix Sophorae Tonkinensis 2g, Wan Nianbai 3g; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, incapsulate shell, the capsule of adult normal's one day consumption must be met.
Be used for the treatment of herpes zoster.Oral, every bu is taken for twice sooner or later.
Specific embodiment 2
Take Folium sidae alnifoliae 4g, Herba euphorbiae lunulatae 2g, Radix Pulsatillae 5g, Caulis Spatholobi 6g, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 4g, rheumatism wood 3g, Radix Levistici Officinalis 4g, Lignum Santali Albi 3g, Herba Acalyphae 3g, Flos Hibisci Mutabilis 5g, Folium Eriobotryae 3g, Fructus Trichosanthis 2g, Caulis Akebiae 1g, Cortex Phellodendri 4g, Radix Sophorae Tonkinensis 2g, Wan Nianbai 3g; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, must meet the powder of adult normal's one day consumption.
Be used for the treatment of herpes zoster.Oral, once a day.
Specific embodiment 3
Take Folium sidae alnifoliae 4g, Herba euphorbiae lunulatae 2g, Radix Pulsatillae 5g, Caulis Spatholobi 6g, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 4g, rheumatism wood 3g, Radix Levistici Officinalis 4g, Lignum Santali Albi 3g, Herba Acalyphae 3g, Flos Hibisci Mutabilis 5g, Folium Eriobotryae 3g, Fructus Trichosanthis 2g, Caulis Akebiae 1g, Cortex Phellodendri 4g, Radix Sophorae Tonkinensis 2g, Wan Nianbai 3g; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, then adds appropriate dextrin and correctives, granulates according to this area common process, and packaging, can obtain the granule meeting adult normal's one day consumption.
Be used for the treatment of herpes zoster.Oral, every bu morning, noon and afternoon take for three times.

Claims (1)

1. treat the Chinese medicine of herpes zoster for one kind, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Folium sidae alnifoliae 4 parts, Herba euphorbiae lunulatae 2 parts, the Radix Pulsatillae 5 parts, Caulis Spatholobi 6 parts, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 4 parts, 3 parts, rheumatism wood, Radix Levistici Officinalis 4 parts, 3 parts, Lignum Santali Albi, Herba Acalyphae 3 parts, Flos Hibisci Mutabilis 5 parts, Folium Eriobotryae 3 parts, Fructus Trichosanthis 2 parts, Caulis Akebiae 1 part, Cortex Phellodendri 4 parts, the root 2 parts of HUAMU indigo plant, Wan Nianbai 3 parts.
CN201310685666.0A 2013-12-16 2013-12-16 Traditional Chinese medicine for treating herpes zoster Expired - Fee Related CN103705614B (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105168814A (en) * 2015-09-30 2015-12-23 张晰 Traditional Chinese medicine composition for treating herpes zoster ophthalmicus

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103055069A (en) * 2013-01-29 2013-04-24 中山大学 External Chinese medicine composition for treating postherpetic neuralgia and preparation method of composition
CN103100002A (en) * 2013-02-05 2013-05-15 徐辉 Medicament for treating acute herpes zoster caused by retention of damp-heat in the interior
CN103251740A (en) * 2013-05-21 2013-08-21 张瑞花 External-application Chinese medicinal preparation for treating shingles

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103055069A (en) * 2013-01-29 2013-04-24 中山大学 External Chinese medicine composition for treating postherpetic neuralgia and preparation method of composition
CN103100002A (en) * 2013-02-05 2013-05-15 徐辉 Medicament for treating acute herpes zoster caused by retention of damp-heat in the interior
CN103251740A (en) * 2013-05-21 2013-08-21 张瑞花 External-application Chinese medicinal preparation for treating shingles

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Inventor after: Liu Yan

Inventor after: Li Hui

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Address after: Fengle village Renhe Town of Huaian city in 223100 Jiangsu County of Hongze Province

Patentee after: Jie Weiwei

Address before: 264000 Shandong Province, Yantai city Zhifu District Qishan Street No. 29

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