CN103610937B - A kind of Chinese medicine for the treatment of tumprigenicity cystic hyperplasia of breast - Google Patents
A kind of Chinese medicine for the treatment of tumprigenicity cystic hyperplasia of breast Download PDFInfo
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Abstract
The present invention relates to a kind of Chinese medicine for the treatment of tumprigenicity mastopathy, it is prepared from by the raw medicinal material of following weight proportion: Flos Albiziae 3 parts, Baphicacanthus cusia (Nees) Bremek. 4 parts, Folium sidae alnifoliae 2 parts, the Plantula cucurbitae moschatae 3 parts, Radix Saccolabii distichi 3 parts, Flos Hibisci Mutabilis 5 parts, Folium Sennae 5 parts, Plumula Nelumbinis 1 part, Herba euphorbiae lunulatae 1 part, Flos Daturae 5 parts, Folium Eriobotryae 3 parts, Herba Centipedae 4 parts, Fructus Trichosanthis 2 parts, Caulis Akebiae 1 part, Pericarpium Citri Reticulatae 3 parts, 3 parts, Semen Armeniacae Amarum, Radix Et Rhizoma Rhei 4 parts, the Radix Pulsatillae 6 parts, Radix Sophorae Tonkinensis 2 parts, 6 parts, Radix Glycyrrhizae.Clinical trial certificate, the present invention can safe and effective treatment tumprigenicity mastopathy.
Description
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine for the treatment of tumprigenicity mastopathy.
Background technology
Tumprigenicity cystic hyperplasia of breast is all generally that liver spleen is impaired because of anxiety and rage, and stagnation of QI expectorant is solidifying to be formed " nodule in the breast ".The traditional Chinese medical science thinks many because of body constitution element void, deficiency of YIN of both the lung and kidney, and the deficiency of YIN is hyperactivity of fire then, and the bright Tianjin of fire is expectorant, phlegm-fire condensation nucleation; Or pathogenic fire derived from stagnation of liver-QI, consume cloudy liquid, expectorant coagulates caused by the stagnation of QI.Current tumprigenicity medicinal breast disease treatment mainly applies operation and antibiotic, and spend high, curative effect is low, and side effect is large.Therefore the Chinese medicine researching and developing a kind of safe and effective treatment tumprigenicity mastopathy very has value for clinical application.
Involved by Chinese medicine of the present invention, the present Research of medical material is as follows:
Flos Albiziae: this product is the dry inflorescence of leguminous plant Herba Albiziae Albizia julibrissin Durazz..[nature and flavor] are sweet, flat [return through] GUIXIN, Liver Channel.[function cures mainly] resolving stagnation for tranquilization.For irritability, melancholy insomnia.[usage and dosage] 4.5 ~ 9g.
Baphicacanthus cusia (Nees) Bremek.: this product is the stem and leaf of acanthaceous vegetable acanthaceous indigo.[nature and flavor] bitter in the mouth; Salty; Cold in nature.[return through] returns lung; Stomach; The heart; Liver Channel.[function cures mainly] heat-clearing and toxic substances removing; Cooling blood for hemostasis.Main epidemic febrile disease; High heat headache; Send out speckle; Cough due to lung-heat; Damp-heat dysentery; Jaundice; Erysipelas; Scarlet fever; Measles; Laryngopharynx swelling and pain; Aphtha; Mumps; Drench horse knot scorching; The liver abscess; Spit blood; Epistaxis; Gingival hemorrhage; Metrorrhagia; Furuncle; Snake bite and insect sting.[usage and dosage] 6-15g.
Folium sidae alnifoliae: this product is the leaf of the little Radix Bupleuri of Malvaceae plant.[nature and flavor] are bitter; Pungent; Cold nature.[return through] heart channel.[function cures mainly] clearing away heat-damp and promoting diuresis; Removing toxic substances and promoting subsidence of swelling.Main damp-heat dysentery; Jaundice; Laryngopharynx swelling and pain; Carbuncle sore tumefacting virus; Bee venom sting.[usage and dosage] 30-60g.
The Plantula cucurbitae moschatae: the seedling that this product is sprouted for seed in cucurbitaceous plant Fructus Cucurbitae moschatae mature fruit.[nature and flavor] sweet in the mouth; Light; Warm in nature.[return through] returns liver; Stomach warp.[function cures mainly] dispels the wind; Pain relieving.Main intestinal colic in children; Infantile convulsion; Flu; Rheumatic fever.[usage and dosage] 3-10g.
Radix Saccolabii distichi: this product is the orchid herb that more leaf basin distance is blue.[nature and flavor] are bitter; Cool.[return through] liver; Stomach warp.[function cures mainly] heat-clearing and toxic substances removing.Main mastitis.Usage and dosage] 3-9g.
Flos Hibisci Mutabilis: be the flower of Malvaceae plant Hibisci Mutabilis.[nature and flavor] are pungent; Micro-hardship; Cool.[return through] lung; The heart; Liver Channel.[function cures mainly] heat-clearing and toxic substances removing; Cooling blood for hemostasis; Detumescence and apocenosis.Main cough due to lung-heat; Spit blood; Conjunctival congestion and swelling pain; Metrorrhagia; Leucorrhea; Diarrhoea; Stomachache; Carbuncle; Furuncle; Venom; Burn due to hot liquid or fire; Traumatic injury.[usage and dosage] 9-15g.
Folium Sennae: this product is the dry lobule of leguminous plant narrow leaf Senna fruit Cassia angustifolia Vahl or cassia acutifolia Delile Cassia acutifolia Delile.[nature and flavor] are sweet, bitter, cold.[return through] returns large intestine channel.[function cures mainly] purges heat capable stagnant, relieving constipation, diuretic.Stagnate for accumulation of heat, constipation is suffered from abdominal pain, edema distension.[usage and dosage] 2 ~ 6g.
Plumula Nelumbinis: this product is green radicle (Plumula Nelumbinis) [nature and flavor] hardship in the middle of the mature seed of nymphaeaceae plant lotus Nelumbo nucifera Gaertn., cold.[return through] GUIXIN, kidney channel.[function cures mainly] clearing away heart-fire for tranquillization, restoring normal coordination between the heart and kidney, unsmoothing the sperm and stopping bleeding.For heat attacking the pericardium, unconsciousness and delirium, disarmony between the heart and kidney, insomnia seminal emission, heat in blood is spitted blood.[usage and dosage] 2 ~ 5g.
Herba euphorbiae lunulatae: this product is the herb of Euphorbiaceae euphorbia Herba euphorbiae lunulatae Euphorbia lunulata Bunge.Nature and flavor] bitter in the mouth; Cold nature; Poisonous.[return through] lung; Liver Channel.[function cures mainly] antitussive; Eliminate the phlegm; Eliminating stagnation; Relieve oedema or abdominal distension through diuresis or purgation; Draw out pus by applying a plaster to the affected part; Parasite killing.Main phlegm retention cough with asthma; Edema; Scrofula; Scabies; Innominate toxic swelling.[usage and dosage] 3-9g.
Flos Daturae: this product is the dried floral of plant of Solanaceae datura metel Datura metel L..[nature and flavor] are pungent, temperature; Poisonous.[return through] returns lung, Liver Channel.[function cures mainly] antiasthmatic-antitussive, analgesia, spasmolytic.For asthma and cough, coldness and pain in the epigastrium, rheumatic arthralgia, children's's intermittent infantile convulsion; Surgical anesthesia.[usage and dosage] 0.3 ~ 0.6g
Folium Eriobotryae: this product is the dried leaves of rosaceous plant Folium Eriobotryae Eriobotrya japonica (Thunb.) Lindl..[nature and flavor] are bitter, are slightly cold.[return through] attaches to the lung and stomach meridians.[function cures mainly] clearing away lung-heat to relieve cough, stopping nausea and vomiting by lowering the adverse flow of QI.For cough due to lung-heat, QI rising in reverse order dyspnea with rapid respiration, gastric heat vomiting, dysphoria with smothery sensation is thirsty.[usage and dosage] 6 ~ 9g.
Herba Centipedae: this product is the dry herb of feverfew Herba Centipedae Centipedaminima (L.) A.Br.etAschers..[nature and flavor with return through] are pungent, temperature.Return lung meridian.[function with cure mainly] dispersing wind-cold, clearing the nasal passage, cough-relieving.For headche due to wind-cold, cough with copious phlegm, has a stuffy nose obstructed, nasal sinusitis watery nasal discharge.[usage and consumption] 6 ~ 9g.Suitable amount used externally.
Fructus Trichosanthis: this product is the dry mature fruit of cucurbitaceous plant Fructus Trichosanthis Trichosanthes kirilowii Maxim. or trichosanthes rosthornii Harms Trichosan-thes rosthornii Harms.[nature and flavor] sweet, micro-hardship, cold.[return through] returns lung, stomach, large intestine channel.[function cures mainly] clearing away heat and eliminating phlegm, relieving stuffiness of the chest by dispersing aggregation of pathogens, moisturizes laxation.For cough due to lung-heat, the turbid Huang of expectorant is thick, obstruction of qi in the chest and cardialgia, blocked-up chest feeling of fullness, acute mastitis, lung abscess, and acute appendicitis swells and ache, constipation.[usage and dosage] 9 ~ 15g.
Caulis Akebiae: this product is Teng's stem of plants of Lardizabalaceae Caulis Akebiae, threeleaf akebia or Caulis Akebiae.[nature and flavor] are bitter; Cold in nature.[return through] heart; Spleen; Kidney; Small intestinal; Urinary bladder channel.[function cures mainly] clearing away heat and promoting diuresis; Blood circulation and channel invigorating.Main red urine is red; Stranguria with turbid discharge; Edema; Irritable feverish sensation in the chest; Larynx larynx pain; Aphtha of the mouth and tongue; Rheumatic arthralgia; Galactostasis; Amenorrhea; Dysmenorrhea.[usage and dosage] 3-6g.
Pericarpium Citri Reticulatae: this product is the dry mature skin of rutaceae orange Citrus reticulata Blanco and variety thereof.[nature and flavor] are bitter, pungent, temperature.[return through] returns lung, spleen channel.[function cures mainly] regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm.For fullness in the epigastrium and chest, lack of appetite and vomiting, cough with copious phlegm.[usage and dosage] 3 ~ 9g.
Semen Armeniacae Amarum: this product is the dry seed of the bitter in the mouth such as rosaceous plant Fructus Pruni or Prunus armeniaca L.var.ansu Maxim..[nature and flavor] are bitter; Temperature; Poisonous.[return through] lung; Spleen; Large intestine channel.[function cures mainly] expelling phlegm for arresting cough; Relieving asthma; Intestine moistening; The therapeutic method to keep the adverse QI flowing downwards opens numbness.Main exogenous cough; Dyspnea with fullness of the chest; The cough due to dryness; Cold renal mass; Infantile convulsion; The thoracic obstruction; Stomachache due to dyspepsia; Metrorrhagia; Deaf; Infantile malnutrition with edema and abdominal distention; Damp-heat gonorrhoea; Scabies; Sore throat; Dryness of the intestine constipation.[usage and dosage] 3-10g.
Radix Et Rhizoma Rhei: this product is polygonum rheum palmatum Rheum palmatum L., Rheum tanguticum Rheum tanguticum Maxim.ex Balf。Or Rheum officinale Rheum officinale Baill.Dry root and rhizome.[nature and flavor] are bitter, cold.[return through] returns spleen, stomach, large intestine, liver, pericardium channel.[function cures mainly] purging heat and dredging bowels, removing pathogenic heat from blood and toxic substance from the body, eliminating blood stasis and inducing menstruation.For excess-heat constipation, stagnant stomachache, dysentery is not well, jaundice due to damp-heat, and heat in blood tells nosebleed, conjunctival congestion, pharyngeal swelling, abdominalgia with intestinal abscess, carbuncle furuncle, blood stasis amenorrhea, traumatic injury, external treatment burn due to hot liquid or fire; Upper gastrointestinal hemorrhage.Radix et Rhizoma Rhei (stir-fried with wine) is apt to clear part of the body cavity above the diaphragm housing the heart and lungs noxious heat in the blood system.For conjunctival congestion pharyngeal swelling, gingivitis.Radix Et Rhizoma Rhei rushes down exerts oneself to delay, eliminating fire and detoxication.For pathogenic fire,toxin and furuncles.Charred Radix Et Rhizoma Rhei cooling blood and removing stasis stops blooding.Stasis of blood hemorrhage is had for heat in blood.[usage and dosage] 3 ~ 30g.
The Radix Pulsatillae: this product is the dry root of ranunculaceae plant Radix Pulsatillae Pulsatilla chinensis (Bge.) Regel.[nature and flavor] are bitter, cold.[return through] returns stomach, large intestine channel.[function cures mainly] heat-clearing and toxic substances removing, eliminating pathogenic heat from blood to cure dysentery.For toxic-heat and blood stasis, pudendal pruritus leukorrhagia, amebic dysentery.[usage and dosage] 9 ~ 15g.
Radix Sophorae Tonkinensis: this product is pulse family anil HUAMU blue Indigofera Kirilowii Maxim. ex Palibin, is used as medicine with root.[nature and flavor] are bitter, cold.[function cures mainly] heat-clearing and toxic substances removing, reducing swelling and alleviating pain, relieving constipation.For laryngopharynx swelling and pain, cough due to lung-heat, jaundice, constipation with heat retention; Swelling and pain of hemorrhoid is controlled in external, snake bite and insect sting.
Radix Glycyrrhizae: this product is the Root and Rootstock of pulse family glycyrrhiza genus Radix Glycyrrhizae Glycyrrhiza uralensis Fisch..Nature and flavor] sweet, flat.[return through] GUIXIN, lung, spleen, stomach warp.[function cures mainly] invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.[usage and dosage] 1.5 ~ 9g.
Summary of the invention
The present invention aims to provide a kind of Chinese medicine for the treatment of tumprigenicity mastopathy, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective healing tumprigenicity mastopathy.
In order to achieve the above object, the present invention is by the following technical solutions:
A kind of Chinese medicine for the treatment of tumprigenicity mastopathy, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Flos Albiziae 3 parts, Baphicacanthus cusia (Nees) Bremek. 4 parts, Folium sidae alnifoliae 2 parts, the Plantula cucurbitae moschatae 3 parts, Radix Saccolabii distichi 3 parts, Flos Hibisci Mutabilis 5 parts, Folium Sennae 5 parts, Plumula Nelumbinis 1 part, Herba euphorbiae lunulatae 1 part, Flos Daturae 5 parts, Folium Eriobotryae 3 parts, Herba Centipedae 4 parts, Fructus Trichosanthis 2 parts, Caulis Akebiae 1 part, Pericarpium Citri Reticulatae 3 parts, 3 parts, Semen Armeniacae Amarum, Radix Et Rhizoma Rhei 4 parts, the Radix Pulsatillae 6 parts, Radix Sophorae Tonkinensis 2 parts, 6 parts, Radix Glycyrrhizae.
Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:
1, physical data
Inventor collects 50 routine female tumor mastopathy patients altogether between in February ,-2013 in June, 2009, age 23-54 year, course of disease 2-12 month.Be divided at random: treatment group 25 example, matched group 25 example.Two groups of data there was no significant differences such as sex, age, have comparability.
2, test method
2.1 Therapeutic Method
Matched group takes ease pill, by specification use, 30 days courses for the treatment of.
The capsule that the oral the present invention for the treatment of group obtains according to specific embodiment 1, every day 2 times.30 days courses for the treatment of.
2.2 observation items: before and after experiment, to pain, lump, tuberosity size, body temperature and blood parameters chemical examination record.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
Recovery from illness: clinical symptoms all disappears, test chamber inspection is normal, has no recurrence in half a year.Take a turn for the better: clinical symptom relief, lab testing improvement or normal.Invalid: clinical symptoms, lab testing are without being clearly better or increasing the weight of.
3.2 treatment statistical results are in table 1.
Table 1 liang group comparitive study
| Group | n | Recovery from illness | Take a turn for the better | Invalid | Untoward reaction example | Total effective rate (%) |
| Treatment group | 25 | 18 | 6 | 1 | 1（4%） | 96% |
| Matched group | 25 | 11 | 6 | 8 | 1（4%） | 68% |
Visible, the medicine that the present invention obtains can safe and effective treatment tumprigenicity mastopathy.
Detailed description of the invention
In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Specific embodiment 1
Take Flos Albiziae 3g, Baphicacanthus cusia (Nees) Bremek. 4g, Folium sidae alnifoliae 2g, Plantula cucurbitae moschatae 3g, Radix Saccolabii distichi 3g, Flos Hibisci Mutabilis 5g, Folium Sennae 5g, Plumula Nelumbinis 1g, Herba euphorbiae lunulatae 1g, Flos Daturae 5g, Folium Eriobotryae 3g, Herba Centipedae 4g, Fructus Trichosanthis 2g, Caulis Akebiae 1g, Pericarpium Citri Reticulatae 3g, Semen Armeniacae Amarum 3g, Radix Et Rhizoma Rhei 4g, Radix Pulsatillae 6g, Radix Sophorae Tonkinensis 2g, Radix Glycyrrhizae 6g, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, incapsulate shell, the capsule of adult normal's one day consumption must be met.
Be used for the treatment of tumprigenicity mastopathy.Oral, every bu is taken for twice sooner or later.
Specific embodiment 2
Take Flos Albiziae 3g, Baphicacanthus cusia (Nees) Bremek. 4g, Folium sidae alnifoliae 2g, Plantula cucurbitae moschatae 3g, Radix Saccolabii distichi 3g, Flos Hibisci Mutabilis 5g, Folium Sennae 5g, Plumula Nelumbinis 1g, Herba euphorbiae lunulatae 1g, Flos Daturae 5g, Folium Eriobotryae 3g, Herba Centipedae 4g, Fructus Trichosanthis 2g, Caulis Akebiae 1g, Pericarpium Citri Reticulatae 3g, Semen Armeniacae Amarum 3g, Radix Et Rhizoma Rhei 4g, Radix Pulsatillae 6g, Radix Sophorae Tonkinensis 2g, Radix Glycyrrhizae 6g, add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, must meet the powder of adult normal's one day consumption.
Be used for the treatment of tumprigenicity mastopathy.Oral, once a day.
Specific embodiment 3
Take Flos Albiziae 3g, Baphicacanthus cusia (Nees) Bremek. 4g, Folium sidae alnifoliae 2g, Plantula cucurbitae moschatae 3g, Radix Saccolabii distichi 3g, Flos Hibisci Mutabilis 5g, Folium Sennae 5g, Plumula Nelumbinis 1g, Herba euphorbiae lunulatae 1g, Flos Daturae 5g, Folium Eriobotryae 3g, Herba Centipedae 4g, Fructus Trichosanthis 2g, Caulis Akebiae 1g, Pericarpium Citri Reticulatae 3g, Semen Armeniacae Amarum 3g, Radix Et Rhizoma Rhei 4g, Radix Pulsatillae 6g, Radix Sophorae Tonkinensis 2g, Radix Glycyrrhizae 6g, add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merge decoction liquor, concentrated, add appropriate dextrin and correctives again, granulate according to this area common process, packaging, can obtain the granule meeting adult normal's one day consumption.
Be used for the treatment of tumprigenicity mastopathy.Oral, every bu morning, noon and afternoon take for three times.
Claims (1)
1. treat the Chinese medicine of tumprigenicity mastopathy for one kind, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Flos Albiziae 3 parts, Baphicacanthus cusia (Nees) Bremek. 4 parts, Folium sidae alnifoliae 2 parts, the Plantula cucurbitae moschatae 3 parts, Radix Saccolabii distichi 3 parts, Flos Hibisci Mutabilis 5 parts, Folium Sennae 5 parts, Plumula Nelumbinis 1 part, Herba euphorbiae lunulatae 1 part, Flos Daturae 5 parts, Folium Eriobotryae 3 parts, Herba Centipedae 4 parts, Fructus Trichosanthis 2 parts, Caulis Akebiae 1 part, Pericarpium Citri Reticulatae 3 parts, 3 parts, Semen Armeniacae Amarum, Radix Et Rhizoma Rhei 4 parts, the Radix Pulsatillae 6 parts, Radix Sophorae Tonkinensis 2 parts, 6 parts, Radix Glycyrrhizae.
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