CN107812165A - A kind of Chinese medicine for being used to treat acute pancreatitis - Google Patents

Abstract

The present invention relates to a kind of Chinese medicine for being used to treat acute pancreatitis, it is prepared by the raw medicinal material of following weight proportion：15 parts of radix bupleuri, 10 parts of Fructus Aurantii, 10 parts of the dried immature fruit of citron orange, 10 parts of radix scutellariae, 12 parts of the root of herbaceous peony, rhizoma pinellinae praeparata l0 parts, 6 parts of prepared RADIX ET RHIZOMA RHEI, 15 parts of jujube, 3 parts of ginger.Clinical experiments have proved that the present invention can safely and effectively treat acute pancreatitis.

Description

A kind of Chinese medicine for being used to treat acute pancreatitis

Technical field

The present invention relates to a kind of Chinese medicine, and in particular to a kind of Chinese medicine for being used to treat acute pancreatitis.

Background technology

Acute pancreatitis is that Different types of etiopathogenises causes pancreatin to activate, using pancreas local inflammation reaction as principal character, companion or not The disease changed with other organ dysfunctions, is one of clinically common acute abdomen, and Etiological is that biliary diseases, crapulence are sudden and violent Food, excessive drinking etc., its incidence of disease are constantly heightened and risen year by year with living standard, and its course of disease is dangerous, complication More, case fatality rate height, its mechanism do not illustrate completely.The name of disease of " pancreatitis " is had no in motherland's medical science, but ancient literature has The largely discussion similar to pancreatitis symptom etc., " abdominal distension fullness sensation in chest, gastral cavilty is when pained, and the side of body of branch two, pharynx diaphragm is obstructed, Gastropathic stomachache." categories such as motherland's medical science " stomachache " " gastropathic stomachache " " epigastric pain " are belonged to according to its genius morbi.Clinic is main To be suffered from abdominal pain with acute severe, Nausea and vomiting, pancreatin increase as main performance.

Medicinal material present Research involved in the present invention is as follows：

Radix bupleuri【Alias】Ground is smoked, Asia puecon Hu, mountain dish, eats grass, faggot.【Source】This product is umbelliferae bupleurum or radix bupleuri scorzoneraefolii Dry root.It is different by character, practise claim " Bupleurum Chinese " and " RADIX BUPLEURI SCORZONERAEFOLII " respectively.Spring, the excavation of season in autumn two, remove cauline leaf and silt, Dry.【Nature and flavor】Hardship, it is slightly cold.【Channel tropism】Return liver, gallbladder channel.【Major function】It is soothing the liver in inducing diaphoresis, rising Yang.Sent out for catching a cold Heat, fevers and chills alternate, distending pain in the chest and hypochondrium, irregular menstruation, sub-official prolapses, prolapse of the anus.【Usage and dosage】It is for oral administration：Decoct soup, 3~9g.【Pay attention to】 The dry rhizome of bigleaf thorowax root, the dense link in surface is poisonous, can not work as radix bupleuri and use.【Take passages】《Chinese book on Chinese herbal medicine》.

The tuber of pinellia【Alias】The three leaf tuber of pinellia, three leaves are old, jumps of three steps, numb semen myristicae, swallow tail, literary, water jade.【Source】This product is day south The dry tuber of the star section plant tuber of pinellia.Summer, the excavation of season in autumn two, clean, remove crust and fibrous root, dry.【Nature and flavor】It is pungent, temperature； It is poisonous.【Channel tropism】Returns spleen, stomach, lung channel.【Major function】It is eliminating dampness and eliminating phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass.For abundant expectoration cough and asthma, Phlegm retention anti-dazzle nervous, anemophlegmatic vertigo, phlegm and headache, vomiting gastric disorder causing nausea, chest gastral cavity ruffian, globus hysteriocus；Controlling outward carbuncle swells subcutaneous nodule is used in life.Pinellia is more For stopping nausea and vomiting by lowering the adverse flow of QI.【Usage and dosage】It is for oral administration：Decoct soup, 3~9g.【Pay attention to】Deficiency of Yin cough caused by dryness, injury thirst, blood trouble and sticky sputum person prohibit Clothes, pregnant women should cautiously take.Should not be with Aconitum medicinal material with use.【Take passages】《Chinese book on Chinese herbal medicine》.

Ginger【Alias】Ginger.【Source】This product is the new fresh quench stem of zingiber.Autumn, the excavation of season in winter two, remove fibrous root And silt.【Nature and flavor】It is pungent, tepor.【Channel tropism】Return lung, spleen, stomach.【Major function】Relieving exterior syndrome and dispelling cold, warming middle energizer to arrest vomiting, resolving sputum stop Cough.For anemofrigid cold, gastrofrigid vomiting, cold productive cough is coughed.【Usage and dosage】It is for oral administration：Decoct soup, 3~9g.【Pay attention to】It is long to eat ginger, accumulated heat Suffer from mesh.All sick hemorrhoid people eat more and wine, and it is very fast to found hair.Ulcerative carbuncle people eats then raw evil meat more.【Take passages】《Chinese book on Chinese herbal medicine》.

Jujube【Alias】【Source】This product is the dry mature fruit of Rhamnaceae jujube jujube.Adopted during autumn fruit maturation Receive, dry.Its root, bark are also used as medicine, and can adopt at any time.【Nature and flavor】It is sweet, temperature.【Channel tropism】Returns spleen, stomach.【Major function】Bowl spares benefit Gas, nourishing blood and tranquilization.For spleen eating less, weak loose stool, hysteria of womam.Anti-inflammatory, hemostasis, antidiarrheal.For tracheitis, enteritis, dysentery Disease, uterine bleeding；Traumatism and bleeding is controlled in external application.Promoting the circulation of qi, promoting blood circulation, menstruation regulating.It is red to collapse for irregular menstruation, leukorrhea.【Usage and dosage】It is for oral administration： Decoct soup, 6~15g.【Pay attention to】All to have damp phlegm, stagnate, tooth disease, worm patient be not suitable.Epigastric fullness, in full vomiter avoid it.It is more The dynamic wind of food, spleen is instead by disease.【Take passages】《Chinese book on Chinese herbal medicine》.

Radix scutellariae【Alias】Radix Scutellariae, scutellaria tea, tsuchikane tea root.【Source】This product is the dry root of labiate radix scutellariae. Spring, the excavation of season in autumn two, remove fibrous root and silt, hit tertia after solarization, dry.【Nature and flavor】Hardship, tremble with fear.【Channel tropism】Return lung, courage, spleen, Large intestine, small intestinl channel.【Major function】Heat-clearing and damp-drying drug, purging intense heat and detonicating, hemostasis are antiabortive.It is damp and hot for damp-warm syndrome, heat temperature evil of vomitting uncomfortable in chest Feeling of fullness, rush down dysentery, jaundice, cough with lung heat, hyperpyrexia polydipsia, blood-head tells nosebleed, carbuncle sore tumefacting virus, fetal irritability.【Usage and dosage】It is for oral administration：Decoct Soup, 3-9g.【Pay attention to】Fructus Corni, keel make for it.It is real to dislike green onion.Fear cinnabar, tree peony, black false hellebore.【Take passages】《Chinese book on Chinese herbal medicine》.

The dried immature fruit of citron orange【Source】This product is rutaceae bitter orange and its drying young fruit of variety or sweet orange.5~June collects From the fruit fallen, impurity is removed, crosscutting from middle part is two halves, is dried or low temperature drying, and smaller directly dries or low temperature drying. 【Nature and flavor】It is bitter, pungent, sour, temperature.【Channel tropism】Returns spleen, stomach.【Major function】Relieving stagnant Qi disperse accumulations, resolving sputum dissipate ruffian.For internal stagnation, ruffian Full distending pain, weight after rush down dysentery, constipation, the phlegm stagnant gas resistance obstruction of qi in the chest, accumulation of pathogens in chest；Gastroptosis, prolapse of the anus, the prolapse of uterus.【Usage and dosage】It is interior Clothes：Decoct soup, 3~9g.【Pay attention to】Pregnant woman uses with caution.【Take passages】《Chinese book on Chinese herbal medicine》.

The root of herbaceous peony【Alias】Chinese herbaceous peony.【Source】This product is the dry root of ranunculaceae plant Chinese herbaceous peony.Summer, the excavation of season in autumn two, are washed Only, remove end to end and radicula, put and boiled again after crust or peeling are removed after being boiled in boiling water, dried.【Nature and flavor】Bitter, acid, is slightly cold.【Return Through】Return liver, the spleen channel.【Major function】Smooth liver and relieve pain, nourishing blood for regulating menstruation, astringing YIN to stop sweating.For dizziness of having a headache, hypochondriac pain, stomachache, four limbs Contraction pain, blood deficiency chlorosis, irregular menstruation, spontaneous perspiration, night sweat.【Usage and dosage】It is for oral administration：Decoct soup, 6~15g.【Pay attention to】Unsuitable and black false hellebore With use.【Take passages】《Chinese book on Chinese herbal medicine》.

Fructus Aurantii【Source】This product is rutaceae bitter orange and its drying immature fruit of variety.July pericarp still Harvested when green, crosscutting from middle part is two halves, is dried or low temperature drying.【Nature and flavor】It is bitter, pungent, sour, temperature.【Channel tropism】Returns spleen, stomach. 【Major function】Regulating the flow of QI to ease the stomach, the stagnant dissipate-swelling of row.For the chest side of body stagnation of the circulation of vital energy, turgor pain, accumulation of food in the stomach and intes tine due to indigestion, stop in phlegm and retained fluid；Gastroptosis, take off Anus, sub-official prolapses.【Usage and dosage】It is for oral administration：Decoct soup, 3~9g.【Pay attention to】Pregnant woman uses with caution.Qi and blood weak person can not take.【Take passages】 《Chinese book on Chinese herbal medicine》.

Prepared RADIX ET RHIZOMA RHEI【Alias】Huang Liang, fire ginseng, skin such as, general, Radixet Rhizoma Rhei, Sichuan troops, high, another name for Sichuan Province rheum officinale, cow tongue rheum officinale, brocade Line, raw army, fragrant rheum officinale, R.hoofshaped.【Source】This product is polygonum rheum palmatum, Rheum tanguticum Maxim or Rheum officinale Dry root and rhizome.Autumn end cauline leaf, which is withered, or secondary spring germination is preceding excavates, and removes radicula, scrapes off crust, valve cutting or section, restricts and wear bunchiness Dry or convection drying.【Nature and flavor】Hardship, tremble with fear.【Channel tropism】Returns spleen, stomach, large intestine, liver, pericardium channel.【Major function】Purge heat logical intestines, cool Blood detoxifies, dispelling stasis of blood and stimulating the menstrual flow.For real heat constipation, stagnate stomachache, and rush down dysentery is not well, jaundice with damp-heat pathogen, blood-head tells nosebleed, hot eyes, pharynx swelling, intestines Carbuncle is suffered from abdominal pain, and carbuncle swells furunculosis, blood stasis closed, traumatic injury, controls scald outside；UGB.Prepared RADIX ET RHIZOMA RHEI with wine is apt to clear part of the body cavity above the diaphragm housing the heart and lungs blood Divide heat toxin.For hot eyes pharynx swelling, gingivitis.Prepared RADIX ET RHIZOMA RHEI, which rushes down, exerts oneself to delay, purging intense heat and detonicating.For pathogenic fire,toxin and furuncles.Charred RADIX ET RHIZOMA RHEI cool blood Removing blood stasis and hemostasis.There is stasis of blood haemorrhage for blood-head.【Usage and dosage】It is for oral administration：Decoct soup, 3~30g.【Pay attention to】Deficiency of blood gas is weak, and taste are empty It is cold, before no real heat, stagnant, stasis, and tire, postpartum, careful it all should take.【Take passages】《Chinese book on Chinese herbal medicine》.

The content of the invention

The present invention is intended to provide a kind of Chinese medicine for being used to treat acute pancreatitis, by selecting suitable medicinal material and its matching somebody with somebody Than reaching the purpose for safely and effectively curing acute pancreatitis.

In order to achieve the above object, the present invention uses following technical scheme：

A kind of Chinese medicine for being used to treat eczema acute pancreatitis, it is characterised in that it is by the raw medicinal material of following weight proportion It is prepared：15 parts of radix bupleuri, 10 parts of Fructus Aurantii, 10 parts of the dried immature fruit of citron orange, 10 parts of radix scutellariae, 12 parts of the root of herbaceous peony, rhizoma pinellinae praeparata L0 parts, 6 parts of prepared RADIX ET RHIZOMA RHEI, 15 parts of jujube, 3 parts of ginger.

The beneficial effects of the present invention will now be described with reference to clinical experimental data：

1st, general information

Outpatient service and in hospital patients with acute pancreatitis 61 are collected in inventor in October, 2012 ~ 2013 year altogether between October, are randomly divided into Treatment group 32 and control group 29, treatment group man 24, female 8,3~45 years old age, average age 38.6 years old；Control group man 22, female 7, average age 38.8 years old.2 groups of sexes, age and course of disease comparing difference are not statistically significant, have comparativity.

Diagnostic criteria

Diagnostic criteria according to national acute pancreatitis patients specialized conference：（1）, acute pancreatitis patients show as it is acute lasting Property stomachache (even without stomachache), blood amylase activity increases >=3 times of normal upper limit.Iconography prompting pancreas changes with or without form Become；Other illness are excluded, can be with or without other organ dysfunctions；A small number of case serum amyloid enzymatic activitys are normal or slightly increase It is high；（2）, mild acute pancreatitis：Possess clinical manifestation and the Biochemical changes of acute pancreatitis, and without organ dysfunction or office Portion's complication.It is good to liquid supplementary therapy reaction.

2nd, test method

2.1 treatment method

The oral present invention for the treatment of group is according to capsule made from specific embodiment 3,2 times a day.The course for the treatment of 14 days.

Control group Effect of Oral Metronidazole, carbostyril antibiotic（By specification is taken）, the course for the treatment of 14 days.

3rd, criterion of therapeutical effect and treatment results

3.1 criterion of therapeutical effect

Clinic control：Symptom, sign are alleviated in 3 d, are disappeared in 7 d, blood, amylase in urine are normal.

It is effective：Symptom, sign significantly take a turn for the better in d, and blood, amylase in urine recover normal；

Effectively：Symptom, sign mitigate in 7 d, and blood, amylase in urine have downward trend；

It is invalid：Symptom and sign does not mitigate or deteriorated in 7 d, and blood, amylase in urine do not reduce；

3.2 treatment results are shown in Table 1.

1 two groups of curative effects of table compare

Group	n	Clinic control	It is effective	Effectively	It is invalid	Total effective rate (%)	Cure-remarkable-effectiveness rate
								Treatment group	32	5	15	10	2	93.7%	62.5%
Control group	29	4	10	13	2	93.1%	48.3%

It can be seen that medicine produced by the present invention can safely and effectively treat acute pancreatitis, there is promotional value.

Embodiment

In order to more fully understand and implement the present invention, the present invention is further illustrated with reference to specific embodiment.

Embodiment 1

Weigh：15 grams of radix bupleuri, 10 grams of Fructus Aurantii, 10 grams of the dried immature fruit of citron orange, 10 grams of radix scutellariae, 12 grams of the root of herbaceous peony, rhizoma pinellinae praeparata l0 Gram, 6 grams of prepared RADIX ET RHIZOMA RHEI, 15 grams of jujube, 3 grams of ginger；Add 8 times of amount water, decoct 1.5 hours, filtering；Filter residue adds 6 times of amounts Water, decoct 1 hour, filtering；Merging filtrate, 120 grams are concentrated into, produce the decoction for meeting one day dosage of normal adult.

For treating acute pancreatitis.Orally, taken twice sooner or later per bu.

Embodiment 2

Weigh：15 grams of radix bupleuri, 10 grams of Fructus Aurantii, 10 grams of the dried immature fruit of citron orange, 10 grams of radix scutellariae, 12 grams of the root of herbaceous peony, rhizoma pinellinae praeparata l0 Gram, 6 grams of prepared RADIX ET RHIZOMA RHEI, 15 grams of jujube, 3 grams of ginger；Add 10 times of amount water, decoct 2 hours, filtering；Filter residue adds 8 times of amounts Water, decoct 1.5 hours, filtering；Merging filtrate, concentrate, dry, packaging, produce the powder for meeting one day dosage of normal adult.

For treating acute pancreatitis.Orally, taken twice sooner or later per bu.

Embodiment 3

Weigh：15 grams of radix bupleuri, 10 grams of Fructus Aurantii, 10 grams of the dried immature fruit of citron orange, 10 grams of radix scutellariae, 12 grams of the root of herbaceous peony, rhizoma pinellinae praeparata l0 Gram, 6 grams of prepared RADIX ET RHIZOMA RHEI, 15 grams of jujube, 3 grams of ginger；Add 6 times of amount water, decoct 3 times, decoct 1 hour every time, merge and decoct Boil liquid, concentrate, dry, load capsule shells, produce the capsule for meeting one day dosage of normal adult.

For treating acute pancreatitis.Orally, taken twice sooner or later per bu.

Claims (4)

1. a kind of Chinese medicine for being used to treat acute pancreatitis, it is characterised in that it is by the raw medicinal material system of following weight proportion It is standby to form：15 parts of radix bupleuri, 10 parts of Fructus Aurantii, 10 parts of the dried immature fruit of citron orange, 10 parts of radix scutellariae, 12 parts of the root of herbaceous peony, rhizoma pinellinae praeparata l0 Part, 6 parts of prepared RADIX ET RHIZOMA RHEI, 15 parts of jujube, 3 parts of ginger.

2. it is used for the Chinese medicine of acute pancreatitis as claimed in claim 1, it is characterised in that its preparation method is：Weigh：Radix bupleuri 15 parts, 10 parts of Fructus Aurantii, 10 parts of the dried immature fruit of citron orange, 10 parts of radix scutellariae, 12 parts of the root of herbaceous peony, rhizoma pinellinae praeparata l0 parts, prepared RADIX ET RHIZOMA RHEI 6 Part, 15 parts of jujube, 3 parts of ginger；Add 8 times of amount water, decoct 1.5 hours, filtering；Filter residue adds 6 times of amount water, decocts 1 hour, Filtering；Merging filtrate, 120 parts are concentrated into, produces decoction；Above-mentioned part each means parts by weight.

3. the as claimed in claim 1 Chinese medicine for being used to treat acute pancreatitis, it is characterised in that its preparation method is：Weigh： 15 parts of radix bupleuri, 10 parts of Fructus Aurantii, 10 parts of the dried immature fruit of citron orange, 10 parts of radix scutellariae, 12 parts of the root of herbaceous peony, rhizoma pinellinae praeparata l0 parts are ripe 6 parts of rheum officinale, 15 parts of jujube, 3 parts of ginger；Add 10 times of amount water, decoct 2 hours, filtering；Filter residue adds 8 times of amount water, decocts 1.5 hours, filtering；Merging filtrate, concentrate, dry, packaging, produce powder；Above-mentioned part each means parts by weight.

4. the as claimed in claim 1 Chinese medicine for being used to treat acute pancreatitis, it is characterised in that its preparation method is：Weigh： 15 parts of radix bupleuri, 10 parts of Fructus Aurantii, 10 parts of the dried immature fruit of citron orange, 10 parts of radix scutellariae, 12 parts of the root of herbaceous peony, rhizoma pinellinae praeparata l0 parts are ripe 6 parts of rheum officinale, 15 parts of jujube, 3 parts of ginger；Add 6 times of amount water, decoct 3 times, decoct 1 hour every time, merge decoction liquor, it is dense Contracting, dry, load capsule shells, produce capsule；Above-mentioned part each means parts by weight.