CN104435741A - Rheumatic knee arthritis paralysis removing and collateral dredging medicinal liquor and preparation method - Google Patents

Rheumatic knee arthritis paralysis removing and collateral dredging medicinal liquor and preparation method Download PDF

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CN104435741A
CN104435741A CN201510003864.3A CN201510003864A CN104435741A CN 104435741 A CN104435741 A CN 104435741A CN 201510003864 A CN201510003864 A CN 201510003864A CN 104435741 A CN104435741 A CN 104435741A
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radix
herba
dredging
rheumatism
eliminating
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许福亮
王云海
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Abstract

The invention discloses rheumatic knee arthritis paralysis removing and collateral dredging medicinal liquor. The medicinal liquor is prepared mainly through the following raw materials including, by weight, 10-20 parts of radix rehmanniae recens, 9-15 parts of all grass or roots of Tricarinate Calanthe, 8-12 parts of herbs of tonkin pepper, 7-15 parts of nux vomica, 10-20 parts of radices sileris, 12-18 parts of fructus forsythiae, six to nine parts of gymnadenia conopsea, 9-12 parts of laciniate begonia herbs, 5-10 parts of libanotis buchtormensis, 8-12 parts of polygonum perfoliatum, 7-15 parts of piper kadsura, 9-16 parts of scutellaria baicalensis and three to six parts of sambucus chinensis. The medicinal liquor is effective in treatment and high in cure rate for rheumatic knee arthritis.

Description

Rheumatic gonarthritis rheumatism-eliminating collaterals-dredging medicated wine and preparation method
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to rheumatic gonarthritis rheumatism-eliminating collaterals-dredging medicated wine and preparation method.
Background technology
Rheumatic arthritis is a kind of common acute or chronic ICT.Can recurrent exerbation involve heart.Clinical with joint and muscle migrans miserable, heavily work, pain is for feature.Belong to allergic disease.One of main manifestations of rheumatic fever, mainly with febris acuta and arthralgia onset.Typical performance is slight or moderate heating, migratory polyarthritis, affected joints mostly is the large joint such as knee joint, ankle, shoulder, elbow, wrist, is commonly transferred to another joint by a joint; pathological changes local presents red, swollen, scorching hot, severe pain, and some patients also has several joint to fall ill simultaneously.Atypical patient only has arthralgia and shows without other inflammation, and acute inflammation generally disappeared in 2 ~ 4 weeks, did not stay sequela, but normal recurrent exerbation.If active rheumatism affects heart, then can there is myocarditis, even leave over valve disorder.
Publication No. CN 102743730 A(application number 201210238705.8) Chinese patent literature disclose a kind of expelling wind and removing dampness, reducing swelling and alleviating pain, the Chinese medicinal liquor of killing parasites for relieving itching, comprise Flos Lonicerae, Herba Lysimachiae, 45 kinds of compositions such as Semen Plantaginis, form through soaking in Chinese liquor, be applicable to rheumatoid arthritis, rheumatic arthritis, scapulohumeral periarthritis, gonarthritis, pain of neck, shoulder, waist and leg, athletic injury, various traumatic injury, muscular strain, becomes to hinder congestion and has a pain.Publication No. CN 102397523 A(application number 201110382694.6) Chinese patent literature disclose one and be used for the treatment of rheumatism, the medicine of rheumatoid arthritis and pain of neck, shoulder, waist and leg, this medicine is by taking pill orally and outer washing medicine forms, pill for oral administration is by Pheretima, Nidus Vespae, Zaocys, Scorpio, Scolopendra, Agkistrodon, Radix Notoginseng, Olibanum, Myrrha, Sanguis Draxonis, Herba Asari, Cortex Cinnamomi, Radix Clematidis, Rhizoma Zingiberis, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Flos Carthami, Herba speranskiae tuberculatae, Herba Aristolochiae Mollissimae, Caulis Spatholobi, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Radix Gentianae Macrophyllae, Radix Saposhnikoviae, osteomiosis, Ramulus Cinnamomi, Rhizoma Corydalis, Flos Lonicerae, Radix Rehmanniae Preparata, the Cortex Eucommiae, Radix Glycyrrhizae is made, outer washing medicine is by Herba speranskiae tuberculatae, Herba Aristolochiae Mollissimae, Radix Clematidis, Cortex erythrinae, Fructus Liquidambaris, Ramulus Mori, Pericarpium Zanthoxyli, Folium Artemisiae Argyi, Ramulus Cinnamomi, Flos Carthami, Radix Aconiti, Radix Aconiti Kusnezoffii, Radix Paeoniae Rubra, Caulis Sinomenii, Caulis Piperis Kadsurae, Flos Caryophylli, and the Radix Angelicae Dahuricae is made.
In modern medicine, the therapeutic scheme that the traditional Chinese medical science adopts, is compared to the conventional anti-inflammatory analgesic of doctor trained in Western medicine and immune suppressant drug, more safe and effective, but part traditional Chinese medical science formula existing defects, causes drug effect not obvious, so also need the research further strengthened this aspect Chinese medicine.
Summary of the invention
For the problem of prior art, the object of this invention is to provide a kind of Be very effective, take the wide rheumatic gonarthritis rheumatism-eliminating collaterals-dredging medicated wine of safe and applicable.
Technical scheme of the present invention is:
Rheumatic gonarthritis rheumatism-eliminating collaterals-dredging medicated wine, is prepared from primarily of following bulk drugs, is weight portion: Radix Rehmanniae 10-20; Herba seu Radix Calanthes 9-15; Herba Piperris Tonkinensis 8-12; Semen Strychni 7-15; Radix Saposhnikoviae 10-20; Fructus Forsythiae 12-18; Rhizoma Gymnadeniae 6-9; Herba Begoniae Laciniatae 9-12; Radix Libanotidis buchotomensis 5-10; Herba Polygoni Perfoliati 8-12; Radix seu Caulis fici Martinii grass 7-15; Radix Scutellariae 9-16; Rhizoma seu Herba Elatostematis stewardii 3-6.
Preferably: Radix Rehmanniae 12-18; Herba seu Radix Calanthes 11-13; Herba Piperris Tonkinensis 9-11; Semen Strychni 10-12; Radix Saposhnikoviae 12-18; Fructus Forsythiae 14-16; Rhizoma Gymnadeniae 7-8; Herba Begoniae Laciniatae 10-11; Radix Libanotidis buchotomensis 6-9; Herba Polygoni Perfoliati 9-11; Radix seu Caulis fici Martinii grass 9-13; Radix Scutellariae 11-14; Rhizoma seu Herba Elatostematis stewardii 4-5.
More preferably: Radix Rehmanniae 15; Herba seu Radix Calanthes 12; Herba Piperris Tonkinensis 10; Semen Strychni 11; Radix Saposhnikoviae 15; Fructus Forsythiae 15; Rhizoma Gymnadeniae 7.5; Herba Begoniae Laciniatae 10.5; Radix Libanotidis buchotomensis 7.5; Herba Polygoni Perfoliati 10; Radix seu Caulis fici Martinii grass 11; Radix Scutellariae 12.5; Rhizoma seu Herba Elatostematis stewardii 4.5.
The preparation method of described rheumatic gonarthritis rheumatism-eliminating collaterals-dredging medicated wine, its step is as follows:
(1) Radix Rehmanniae is cleaned, removing impurity, add soak with ethanol 30-50 minute after shave (preferably: soak 35-45 minute; Be more preferably: soak 40 minutes), pour in mortar and smash to pieces, filter with gauze extruding squeeze juice;
(2) get Semen Strychni to clean, be placed in marmite, add milk steaming and decocting 15-25 minute (preferred: steaming and decocting 20 minutes), take out peeling, more fried in yellow with Oleum Sesami, drain and pulverize;
(3) get refined honey, add boiled water dilution, drench in clean Radix seu Caulis fici Martinii grass, mix moistening thoroughly, be placed in parch container, with slow fire heating, fry to strong yellow, time tack-free, taking-up is dried in the air cool;
(4) by clean for other residue medical material wash quicklies, pulverize and sieve together with step (2) (3) made medical material after drying, add Chinese liquor, the micro-heating of little fire, then add step (1) gained juice, stir;
(5) stating step (4) gained mixed liquor 15-25 days is (preferred: to leave standstill 18-22 days; Be more preferably: leave standstill 20 days), cross and filter medicinal residues, obtain rheumatism-eliminating collaterals-dredging medicated wine.
The preparation method of described rheumatic gonarthritis rheumatism-eliminating collaterals-dredging medicated wine, in step (1), the concentration of ethanol is that 30%-50%(is preferred: concentration of alcohol is 40%).
The preparation method of described rheumatic gonarthritis rheumatism-eliminating collaterals-dredging medicated wine, the amount that step (2) adds milk is that the 6-9 of medical material weight is doubly (preferred: milk amount is 7-8 times of medical material weight; Be more preferably: milk amount is 7.5 times of medical material weight).
The preparation method of described rheumatic gonarthritis rheumatism-eliminating collaterals-dredging medicated wine, pulverized 50-80 mesh sieve (preferred: to pulverize 60-70 mesh sieve in step (4); Be more preferably: pulverized 65 mesh sieves).
The preparation method of described rheumatic gonarthritis rheumatism-eliminating collaterals-dredging medicated wine, in step (4), the number of degrees of Chinese liquor are 38 degree.
The preparation method of described rheumatic gonarthritis rheumatism-eliminating collaterals-dredging medicated wine, it is that the 10-15 of medical material weight is doubly (preferred: to add 11-14 times that Chinese liquor amount is medical material weight that step (4) adds Chinese liquor amount; Be more preferably: add 12.5 times that Chinese liquor amount is medical material weight).
The preparation method of described rheumatic gonarthritis rheumatism-eliminating collaterals-dredging medicated wine, the little fiery slight fever 20-30 of step (4) minute is (preferred: little fiery slight fever 22-28 minute; Be more preferably: little fiery slight fever 25 minutes).
Rheumatic gonarthritis rheumatism-eliminating collaterals-dredging medicinal liquor prescription science provided by the invention, preparation method is simple.In addition, its excellent part also shows:
1, gained medicine of the present invention is for rheumatic gonarthritis, evident in efficacy, cure rate is high;
2, prescription compatibility of the present invention rigorous, according to clinical experience for many years, repeatedly test and obtain;
3, the medicine selected by prescription has effect of expelling wind and removing dampness, relaxing muscles and tendons and activating QI and blood in the collateral, improves uncomfortable disease rapidly.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
Radix Rehmanniae: base is former: be the fresh rhizome of scrophulariaceae rehmannia glutinosa plant.Nature and flavor: sweetness and bitterness, cold.Gui Jing: enter the heart, liver, kidney channel.Function cures mainly: heat clearing away, and removing heat from blood promotes the production of body fluid.Control epidemic febrile disease impairment of YIN, large hot excessive thirst, crimson tongue, coma, macule, spit blood, epistaxis, asthenia hectic fever due to YIN-deficiency, hemoptysis, quenches one's thirst, constipation, metrorrhagia.
Herba seu Radix Calanthes: base is former: be herb or the rhizome of the orchid family Calanthe plant calanthe.Composition: fresh rhizome is containing indoles and glucosides thereof: calanthe glycosides A, B, dihydro phenanthrene derivative, indican, the luxuriant and rich with fragrance alcohol of calanthe, Ryukyu's calanthe glycosides; Indoles alkaloid class: couroupitine A, indirubin etc.The property of medicine: pungent, micro-hardship, is slightly cold.Function cures mainly: heat-clearing and toxic substances removing, promoting blood circulation and stopping pain.Cure mainly carbuncle, laryngopharynx swelling and pain, hemorrhoid, rheumatic arthralgia, traumatic injury.
Herba Piperris Tonkinensis: base is former: be the Herb of Piperaceae Piper plant optical axis ramie leaf Betel.Composition: aerial parts contains: sitosterol, 4-alkene-6-hydroxyl-3-stigmastane ketone, ergosterol peroxide, alkaloid: piperine, Piperyline, Guinea piperamide A, B etc.The property of medicine: Guangzhou army " conventional Chinese herbal medicine handbook ": " pungent, temperature." function cures mainly: expelling wind and cold, promoting blood flow to regulate menstruation, reducing swelling and alleviating pain.Cure mainly anemofrigid cold, rheumatic arthralgia, coldness and pain in the epigastrium, toothache, menoxenia, dysmenorrhea, treating swelling and pain by traumatic injury, snake bite and insect sting.
Semen Strychni: base is former: be the mature seed of loganiaceae plant Semen Strychni.Pluck during fruit maturation, removing sarcocarp, takes out seed, dries.Chemical analysis: containing brucine, strychnine, α-and β-Ke Lubo, vomicine, novacine, icajine, loganin etc.Nature and flavor: bitter, cold, poisonous.Function cures mainly: loose heat in blood, detumescence, pain relieving.Control throat arthralgia pain, swollen ulcer drug, migratory arthralgia pain, fracture.And control facial paralysis, myasthenia gravis.Removing obstruction in the collateral to relieve pain, mass dissipating and swelling eliminating.For rheumatoid arthritis stubborn, paralysis and numbness, injury from falling down, ulcer sore pain.
Radix Saposhnikoviae: nature and flavor: pungent, sweet, tepor.Gui Jing: return bladder, lung, spleen, Liver Channel.Effect: expelling pathogenic wind from the body surface, removing dampness to relieve pain.Cure mainly: for affection of exogenous wind-cold, headache general pain, rheumatic arthralgia.
Fructus Forsythiae: nature and flavor with return through: bitter, be slightly cold.Return lung, the heart, small intestine meridian; There is heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, effect of dispelling wind and heat pathogens; For carbuncle, scrofula, acute mastitis, erysipelas, anemopyretic cold, epidemic febrile disease from the beginning of, warm people battalion, high hot excessive thirst, coma sends out speckle, the puckery pain of pyretic stranguria.
Rhizoma Gymnadeniae: base is former: be the tuber of orchid Rhizoma Gymnadeniae and gymnadenia crassinervis Finet.Nature and flavor: sweet are flat.Gui Jing: " Chinese herbal medicine is commonly used in Sichuan ": " enter lung, spleen, stomach warp." function cures mainly: benefiting vital QI and blood, promoting the production of body fluid to quench thirst.Control cough and asthma due to lung deficiency, asthenia is become thin, neurasthenia, and chronic diarrhea is lost blood, leukorrhagia, and breast is few, chronic hepatitis.
Herba Begoniae Laciniatae: base is former: be the Herb of Begoniaceae plant Begonia pedatifida.The whole year can adopt, and cleans, dries.Nature and flavor: " Luchuan book on Chinese herbal medicine ": " sweet, cold." function cures mainly: cure cold cough, rheumatic ostalgia, lumbago, dyspepsia, treating swelling and pain by traumatic injury, furuncle.
Radix Libanotidis buchotomensis: base is former: be the root of samphire Radix Libanotidis buchotomensis.Nature and flavor: " Shaanxi Chinese herbal medicine ": " Xin Gan, temperature." function cures mainly: " Shaanxi Chinese herbal medicine ": " dispersing wind-cold, wind-damp dispelling, analgesia, strengthening the spleen and stomach, cough-relieving, removing toxic substances.Cure cold wind and cold, general aching, cough, headache, toothache, arthralgia, traumatic injury, rheumatism bones and muscles pain, numbness, and Radix Aconiti Taipeici is poisoning ".
Herba Polygoni Perfoliati: base is former: be the herb of polygonaceae plant Herba Polygoni Perfoliati.Autumn gathers, and cleans, dries or using fresh herb.Chemical analysis: herb is containing flavonoid glycoside, anthracene glycoside, cardiotonic glycoside, phenols, aminoacid, organic acid, tannin and saccharide (sucrose about 7.48%, reducing sugar about 3.4%, starch 2.884%).Nature and flavor: bitter are flat.Function cures mainly: inducing diuresis to remove edema, and heat clearing away is invigorated blood circulation, removing toxic substances.Harness the river swollen, jaundice, has loose bowels, malaria, dysentery, pertussis, stranguria with turbid discharge, erysipelas, scrofula, eczema, scabies.
Radix seu Caulis fici Martinii grass: base is former: be rattan and the leaf of the blunt calyx Radix clematidis floridae of ranunculaceae plant.Nature and flavor: bitter in the mouth; Bitter; Cool in nature.Gui Jing: lung, spleen channel.Function cures mainly: expelling wind and clearing away heat; With network pain relieving.Main rheumatic arthritis; Rubella pruritus; Skin ulcer scabies; Toxic swelling; Acute catarrhal conjunctivitis pain; And dysuria.
Radix Scutellariae: bitter in the mouth, cold in nature, return lung, gallbladder, spleen, large intestine, small intestine meridian.There is heat clearing and damp drying, eliminating fire and detoxication, hemostasis, antiabortive effect.For hygropyrexia, heat-damp in summer, vomiting and nausea uncomfortable in chest, damp and hot feeling of fullness, dysentery, jaundice, cough due to lung-heat, high hot excessive thirst, heat in blood tells nosebleed, carbuncle sore tumefacting virus, frequent fetal movement.
Rhizoma seu Herba Elatostematis stewardii: base is former: be rhizome or the herb of contrayerva Mount Lushan Zlatostema involucratum Franch. Et savat..Spring to autumn gathers herb or rhizome, many using fresh herbs.Nature and flavor: 1. " will planted by Tianmu Mountains of Zhejiang Province medicine ": " warm in nature, acrid in the mouth is bitter." function cures mainly: promoting blood circulation to remove blood stasis, detumescence cough-relieving.Control osteopatia sprain, mumps, amenorrhea, cough.
embodiment 1rheumatic gonarthritis rheumatism-eliminating collaterals-dredging medicated wine, is prepared from primarily of following bulk drugs: Radix Rehmanniae 10g, Herba seu Radix Calanthes 9g, Herba Piperris Tonkinensis 8g, Semen Strychni 7g, Radix Saposhnikoviae 10g, Fructus Forsythiae 12g, Rhizoma Gymnadeniae 6g, Herba Begoniae Laciniatae 9g, Radix Libanotidis buchotomensis 5g, Herba Polygoni Perfoliati 8g, Radix seu Caulis fici Martinii grass 7g, Radix Scutellariae 9g, Rhizoma seu Herba Elatostematis stewardii 3g.The preparation method of above-mentioned rheumatic gonarthritis rheumatism-eliminating collaterals-dredging medicated wine is:
(1) cleaned by Radix Rehmanniae, removing impurity, adds the soak with ethanol 30 minutes of 30% concentration, pours in mortar and smash to pieces after shave, filters with gauze extruding squeeze juice;
(2) get Semen Strychni to clean, be placed in marmite, add the milk steaming and decocting 15 minutes of medical material weight 6 times, take out peeling, more fried in yellow with Oleum Sesami, drain and pulverize;
(3) get refined honey, add boiled water dilution, drench in clean Radix seu Caulis fici Martinii grass, mix moistening thoroughly, be placed in parch container, with slow fire heating, fry to strong yellow, time tack-free, taking-up is dried in the air cool;
(4) by clean for other residue medical material wash quicklies, pulverized 50 mesh sieves after drying together with step (2) (3) made medical material, and added 38 degree of Chinese liquor of medical material weight 10 times, the micro-heating of little fire 20 minutes, then add step (1) gained juice, stir;
(5) stating step (4) gained mixed liquor 15 days, crosses and filters medicinal residues, obtain rheumatism-eliminating collaterals-dredging medicated wine.
embodiment 2rheumatic gonarthritis rheumatism-eliminating collaterals-dredging medicated wine, is prepared from primarily of following bulk drugs: Radix Rehmanniae 20g, Herba seu Radix Calanthes 15g, Herba Piperris Tonkinensis 12g, Semen Strychni 15g, Radix Saposhnikoviae 20g, Fructus Forsythiae 18g, Rhizoma Gymnadeniae 9g, Herba Begoniae Laciniatae 12g, Radix Libanotidis buchotomensis 10g, Herba Polygoni Perfoliati 12g, Radix seu Caulis fici Martinii grass 15g, Radix Scutellariae 16g, Rhizoma seu Herba Elatostematis stewardii 6g.The preparation method of above-mentioned rheumatic gonarthritis rheumatism-eliminating collaterals-dredging medicated wine is:
(1) cleaned by Radix Rehmanniae, removing impurity, adds the soak with ethanol 50 minutes of 50% concentration, pours in mortar and smash to pieces after shave, filters with gauze extruding squeeze juice;
(2) get Semen Strychni to clean, be placed in marmite, add the milk steaming and decocting 25 minutes of medical material weight 9 times, take out peeling, more fried in yellow with Oleum Sesami, drain and pulverize;
(3) get refined honey, add boiled water dilution, drench in clean Radix seu Caulis fici Martinii grass, mix moistening thoroughly, be placed in parch container, with slow fire heating, fry to strong yellow, time tack-free, taking-up is dried in the air cool;
(4) by clean for other residue medical material wash quicklies, pulverized 80 mesh sieves after drying together with step (2) (3) made medical material, and added 38 degree of Chinese liquor of medical material weight 15 times, the micro-heating of little fire 30 minutes, then add step (1) gained juice, stir;
(5) stating step (4) gained mixed liquor 25 days, crosses and filters medicinal residues, obtain rheumatism-eliminating collaterals-dredging medicated wine.
Model case: xxx, male, 51 years old.Main suit: without the appearance gonalgia of obvious inducement before 2 years, inconvenient activity, rear Aspirin and erythromycin etc., the state of an illness is taken a turn for the better, but recur again after half a year, whenever cold weather, pain increases the weight of, movable critical constraints, Relapse rate, really unbearably, then seek medical advice, be diagnosed as rheumatic gonarthritis.
Take the present embodiment gained rheumatic knee joint rheumatism-eliminating collaterals-dredging medicated wine, one day twice, each 1-2 two.After taking two weeks, pain relief, after taking one month, symptom is clearly better, and pain disappears substantially, and movable function also recovers substantially, and rear minimizing dosage, take every day once, take two months, the state of an illness does not recur again, is almost recovered, and during Changes in weather, pain does not increase the weight of.
embodiment 3rheumatic gonarthritis rheumatism-eliminating collaterals-dredging medicated wine, is prepared from primarily of following bulk drugs: Radix Rehmanniae 12g, Herba seu Radix Calanthes 11g, Herba Piperris Tonkinensis 9g, Semen Strychni 10g, Radix Saposhnikoviae 12g, Fructus Forsythiae 14g, Rhizoma Gymnadeniae 7g, Herba Begoniae Laciniatae 10g, Radix Libanotidis buchotomensis 6g, Herba Polygoni Perfoliati 9g, Radix seu Caulis fici Martinii grass 9g, Radix Scutellariae 11g, Rhizoma seu Herba Elatostematis stewardii 4g.The preparation method of above-mentioned rheumatic gonarthritis rheumatism-eliminating collaterals-dredging medicated wine is:
(1) cleaned by Radix Rehmanniae, removing impurity, adds the soak with ethanol 35 minutes of 40% concentration, pours in mortar and smash to pieces after shave, filters with gauze extruding squeeze juice;
(2) get Semen Strychni to clean, be placed in marmite, add the milk steaming and decocting 20 minutes of medical material weight 7 times, take out peeling, more fried in yellow with Oleum Sesami, drain and pulverize;
(3) get refined honey, add boiled water dilution, drench in clean Radix seu Caulis fici Martinii grass, mix moistening thoroughly, be placed in parch container, with slow fire heating, fry to strong yellow, time tack-free, taking-up is dried in the air cool;
(4) by clean for other residue medical material wash quicklies, pulverized 60 mesh sieves after drying together with step (2) (3) made medical material, and added 38 degree of Chinese liquor of medical material weight 11 times, the micro-heating of little fire 22 minutes, then add step (1) gained juice, stir;
(5) stating step (4) gained mixed liquor 18 days, crosses and filters medicinal residues, obtain rheumatism-eliminating collaterals-dredging medicated wine.
embodiment 4rheumatic gonarthritis rheumatism-eliminating collaterals-dredging medicated wine, is prepared from primarily of following bulk drugs: Radix Rehmanniae 18g, Herba seu Radix Calanthes 13g, Herba Piperris Tonkinensis 11g, Semen Strychni 12g, Radix Saposhnikoviae 18g, Fructus Forsythiae 16g, Rhizoma Gymnadeniae 8g, Herba Begoniae Laciniatae 11g, Radix Libanotidis buchotomensis 9g, Herba Polygoni Perfoliati 11g, Radix seu Caulis fici Martinii grass 13g, Radix Scutellariae 14g, Rhizoma seu Herba Elatostematis stewardii 5g.The preparation method of above-mentioned rheumatic gonarthritis rheumatism-eliminating collaterals-dredging medicated wine is:
(1) cleaned by Radix Rehmanniae, removing impurity, adds the soak with ethanol 45 minutes of 40% concentration, pours in mortar and smash to pieces after shave, filters with gauze extruding squeeze juice;
(2) get Semen Strychni to clean, be placed in marmite, add the milk steaming and decocting 20 minutes of medical material weight 8 times, take out peeling, more fried in yellow with Oleum Sesami, drain and pulverize;
(3) get refined honey, add boiled water dilution, drench in clean Radix seu Caulis fici Martinii grass, mix moistening thoroughly, be placed in parch container, with slow fire heating, fry to strong yellow, time tack-free, taking-up is dried in the air cool;
(4) by clean for other residue medical material wash quicklies, pulverized 70 mesh sieves after drying together with step (2) (3) made medical material, and added 38 degree of Chinese liquor of medical material weight 14 times, the micro-heating of little fire 28 minutes, then add step (1) gained juice, stir;
(5) stating step (4) gained mixed liquor 22 days, crosses and filters medicinal residues, obtain rheumatism-eliminating collaterals-dredging medicated wine.
Model case: xxx, female, 48 years old.Medical history: because going out by bike for a long time; knee joint is not effectively protected; always there is arthralgia in the recent period; situation about can not walk, taken a little medicine in local clinic, the state of an illness is alleviated to some extent; the recent state of an illness obviously increases the weight of; have a strong impact on orthobiosis, then hospital admission, be diagnosed as rheumatic gonarthritis on inspection.
Recommend through others, take this example gained rheumatism-eliminating collaterals-dredging medicated wine, twice daily, a 1-2 two.After taking one week, pain alleviates to some extent, can light activity, and take one month continuously, patient pain eliminates substantially, can be freely movable, follows up a case by regular visits in half a year, does not occur recurrence.
embodiment 5rheumatic gonarthritis rheumatism-eliminating collaterals-dredging medicated wine, is prepared from primarily of following bulk drugs: Radix Rehmanniae 15g, Herba seu Radix Calanthes 12g, Herba Piperris Tonkinensis 10g, Semen Strychni 11g, Radix Saposhnikoviae 15g, Fructus Forsythiae 15g, Rhizoma Gymnadeniae 7.5g, Herba Begoniae Laciniatae 10.5g, Radix Libanotidis buchotomensis 7.5g, Herba Polygoni Perfoliati 10g, Radix seu Caulis fici Martinii grass 11g, Radix Scutellariae 12.5g, Rhizoma seu Herba Elatostematis stewardii 4.5g.The preparation method of above-mentioned rheumatic gonarthritis rheumatism-eliminating collaterals-dredging medicated wine is:
(1) cleaned by Radix Rehmanniae, removing impurity, adds the soak with ethanol 40 minutes of 40% concentration, pours in mortar and smash to pieces after shave, filters with gauze extruding squeeze juice;
(2) get Semen Strychni to clean, be placed in marmite, add the milk steaming and decocting 20 minutes of medical material weight 7.5 times, take out peeling, more fried in yellow with Oleum Sesami, drain and pulverize;
(3) get refined honey, add boiled water dilution, drench in clean Radix seu Caulis fici Martinii grass, mix moistening thoroughly, be placed in parch container, with slow fire heating, fry to strong yellow, time tack-free, taking-up is dried in the air cool;
(4) by clean for other residue medical material wash quicklies, pulverized 65 mesh sieves after drying together with step (2) (3) made medical material, and added 38 degree of Chinese liquor of medical material weight 12.5 times, the micro-heating of little fire 25 minutes, then add step (1) gained juice, stir;
(5) stating step (4) gained mixed liquor 20 days, crosses and filters medicinal residues, obtain rheumatism-eliminating collaterals-dredging medicated wine.
test example 1the clinical practice of gained rheumatic gonarthritis rheumatism-eliminating collaterals-dredging medicated wine (embodiment 5) of the present invention:
Choose crowd: according to hospital outpatient case history, screening rheumatic gonarthritis patient 348 example, wherein women 160 example, male 188 example, the range of age 18-60 year, more than course of disease half a year.
Before test, patient is divided into two groups at random, experimental group 248 example and matched group 100 routine, two groups in sex, age, the course of disease, the state of an illness etc. without significant difference.Experimental group takes gained rheumatism-eliminating collaterals-dredging medicated wine of the present invention, each 1-2 two (optionally taking), twice daily; Matched group takes other conventional medicines (ibuprofen, naproxen, diclofenac, aspirin etc.).Period in a medicine carries out Continuous Observation to two groups of patients, record symptom and change.
Curative effect determinate standard: reference literature criterion of therapeutical effect, cures: knee joint is red, swollen, scorching hot, severe pain etc. disappears, completely without other clinical uncomfortable diseases; Effective: the gonalgia is clearly better or disappears, slightly swelling, main clinic symptoms disappears; Effective: knee joint malaise symptoms alleviates, occasionally have outbreak, function of joint is improved; Invalid: pain and swelling symptom is without any improvement.
Clinical effectiveness: take two months periods, the therapeutic outcome of two groups is as described in Table 1:
The Chinese medicine used in the present invention, wherein Radix Rehmanniae, Herba seu Radix Calanthes, Herba Begoniae Laciniatae, Herba Polygoni Perfoliati, Fructus Forsythiae have heat-clearing and toxic substances removing, dredging collateral analgesic effect, Herba Piperris Tonkinensis and Rhizoma Gymnadeniae have effect of promoting blood flow to regulate menstruation, invigorating qi and benefiting blood, Semen Strychni, Radix seu Caulis fici Martinii grass, Rhizoma seu Herba Elatostematis stewardii, Radix Libanotidis buchotomensis, there is effect of reducing swelling and alleviating pain, promoting blood circulation to remove blood stasis, all medicines share, add the cooperation of residue accessory drugs, effectively can alleviate the uncomfortable disease such as pain, redness that rheumatic gonarthritis brings, thus raising therapeutic effect, make total effective rate to reach 99.2%.
It should be pointed out that detailed description of the invention is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clear and definite disclosed or according to undoubted the obtaining of the written description of file, the claimed scope of this patent all should be thought.

Claims (10)

1. rheumatic gonarthritis rheumatism-eliminating collaterals-dredging medicated wine, is characterized in that, be prepared from primarily of following bulk drugs, be weight portion: Radix Rehmanniae 10-20; Herba seu Radix Calanthes 9-15; Herba Piperris Tonkinensis 8-12; Semen Strychni 7-15; Radix Saposhnikoviae 10-20; Fructus Forsythiae 12-18; Rhizoma Gymnadeniae 6-9; Herba Begoniae Laciniatae 9-12; Radix Libanotidis buchotomensis 5-10; Herba Polygoni Perfoliati 8-12; Radix seu Caulis fici Martinii grass 7-15; Radix Scutellariae 9-16; Rhizoma seu Herba Elatostematis stewardii 3-6.
2. rheumatic gonarthritis rheumatism-eliminating collaterals-dredging medicated wine as claimed in claim 1, is characterized in that, Radix Rehmanniae 12-18; Herba seu Radix Calanthes 11-13; Herba Piperris Tonkinensis 9-11; Semen Strychni 10-12; Radix Saposhnikoviae 12-18; Fructus Forsythiae 14-16; Rhizoma Gymnadeniae 7-8; Herba Begoniae Laciniatae 10-11; Radix Libanotidis buchotomensis 6-9; Herba Polygoni Perfoliati 9-11; Radix seu Caulis fici Martinii grass 9-13; Radix Scutellariae 11-14; Rhizoma seu Herba Elatostematis stewardii 4-5.
3. rheumatic gonarthritis rheumatism-eliminating collaterals-dredging medicated wine as claimed in claim 1, is characterized in that, Radix Rehmanniae 15; Herba seu Radix Calanthes 12; Herba Piperris Tonkinensis 10; Semen Strychni 11; Radix Saposhnikoviae 15; Fructus Forsythiae 15; Rhizoma Gymnadeniae 7.5; Herba Begoniae Laciniatae 10.5; Radix Libanotidis buchotomensis 7.5; Herba Polygoni Perfoliati 10; Radix seu Caulis fici Martinii grass 11; Radix Scutellariae 12.5; Rhizoma seu Herba Elatostematis stewardii 4.5.
4. the preparation method of the rheumatic gonarthritis rheumatism-eliminating collaterals-dredging medicated wine as described in as arbitrary in claim 1-3, it is characterized in that, step is as follows:
(1) Radix Rehmanniae is cleaned, removing impurity, add soak with ethanol 30-50 minute after shave (preferably: soak 35-45 minute; Be more preferably: soak 40 minutes), pour in mortar and smash to pieces, filter with gauze extruding squeeze juice;
(2) get Semen Strychni to clean, be placed in marmite, add milk steaming and decocting 15-25 minute (preferred: steaming and decocting 20 minutes), take out peeling, more fried in yellow with Oleum Sesami, drain and pulverize;
(3) get refined honey, add boiled water dilution, drench in clean Radix seu Caulis fici Martinii grass, mix moistening thoroughly, be placed in parch container, with slow fire heating, fry to strong yellow, time tack-free, taking-up is dried in the air cool;
(4) by clean for other residue medical material wash quicklies, pulverize and sieve together with step (2) (3) made medical material after drying, add Chinese liquor, the micro-heating of little fire, then add step (1) gained juice, stir;
(5) stating step (4) gained mixed liquor 15-25 days is (preferred: to leave standstill 18-22 days; Be more preferably: leave standstill 20 days), cross and filter medicinal residues, obtain rheumatism-eliminating collaterals-dredging medicated wine.
5. the preparation method of rheumatic gonarthritis rheumatism-eliminating collaterals-dredging medicated wine as claimed in claim 4, is characterized in that, in step (1), the concentration of ethanol is that 30%-50%(is preferred: concentration of alcohol is 40%).
6. the preparation method of rheumatic gonarthritis rheumatism-eliminating collaterals-dredging medicated wine as claimed in claim 4, is characterized in that, the amount that step (2) adds milk is that the 6-9 of medical material weight is doubly (preferred: milk amount is 7-8 times of medical material weight; Be more preferably: milk amount is 7.5 times of medical material weight).
7. the preparation method of rheumatic gonarthritis rheumatism-eliminating collaterals-dredging medicated wine as claimed in claim 4, is characterized in that, pulverizes 50-80 mesh sieve (preferred: to pulverize 60-70 mesh sieve in step (4); Be more preferably: pulverized 65 mesh sieves).
8. the preparation method of rheumatic gonarthritis rheumatism-eliminating collaterals-dredging medicated wine as claimed in claim 4, is characterized in that, in step (4), the number of degrees of Chinese liquor are 38 degree.
9. the preparation method of rheumatic gonarthritis rheumatism-eliminating collaterals-dredging medicated wine as claimed in claim 4, is characterized in that, it is that the 10-15 of medical material weight is doubly (preferred: to add 11-14 times that Chinese liquor amount is medical material weight that step (4) adds Chinese liquor amount; Be more preferably: add 12.5 times that Chinese liquor amount is medical material weight).
10. the preparation method of rheumatic gonarthritis rheumatism-eliminating collaterals-dredging medicated wine as claimed in claim 4, is characterized in that, the little fiery slight fever 20-30 of step (4) minute (preferred: little fiery slight fever 22-28 minute; Be more preferably: little fiery slight fever 25 minutes).
CN201510003864.3A 2015-01-06 2015-01-06 Rheumatic knee arthritis paralysis removing and collateral dredging medicinal liquor and preparation method Pending CN104435741A (en)

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CN106075222A (en) * 2016-07-15 2016-11-09 夏放军 A kind of medicated wine treating arthralgia and preparation method thereof

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CN103432278A (en) * 2013-09-18 2013-12-11 王顺涛 Traditional Chinese medicine for treating rheumatic joint pain

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