CN105012789A - Composition for treating cervical cancer and preparation method thereof - Google Patents
Composition for treating cervical cancer and preparation method thereof Download PDFInfo
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- CN105012789A CN105012789A CN201510495384.3A CN201510495384A CN105012789A CN 105012789 A CN105012789 A CN 105012789A CN 201510495384 A CN201510495384 A CN 201510495384A CN 105012789 A CN105012789 A CN 105012789A
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Abstract
The invention discloses a composition for treating cervical cancer. The composition is mainly prepared from, by mass, 10-16 parts of scutellariae barbatae, 8-15 parts of gentian, 9-16 parts of white peony root, 10-13 parts of black chinese olive leaf, 8-14 parts of limonium bicolor, 6-13 parts of petrea volubilis, 9-14 parts of Stachys palustris L., 7-15 parts of bauhinia championii, 11-17 parts of coix seed, 9-15 parts of conyza japonica, 7-14 parts of patrinia scaniosaefolia, 6-15 parts of Chinese pulsatilla root, 10-14 parts of galium aparine, 8-12 parts of lactuca indica and 9-13 parts of impatiens aquatilis. The composition is obtained through summarization of years of clinical practices, has the functions of clearing away heat and toxic materials, and benefiting qi and nourishing blood and is remarkable in curative effect.
Description
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to the composition and method of making the same for the treatment of cervical cancer.
Background technology
Cervical cancer is one of women's common cancer, and pathogenic factor it be not immediately clear, the disorderly women of early marriage, early childbirth, fecund and sexual life has higher prevalence.Its clinical manifestation is: mostly be contact bleeding in early days; Middle and advanced stage is irregular colporrhagia.Amount of bleeding according to size of tumor, invade and blood vessel situation and different in interstitial, if invasion and attack trunk can cause massive hemorrhage.Young patient also can show as menostaxis, menorrhagia; Gerontal patient is often the irregular colporrhagia of post menopausal.Comparatively early there is vaginal hemorrhage symptom in general exogenic, amount of bleeding is many; Interior raw type is more late there is this symptom.Most of patients has neoplasm, and liquid is white or courageous and upright, can be thin in water sample or water from washing rice shape, or has stench.Patients with terminal infects because of cancerous tissue necrosis companion, can have a large amount of rice water sample or purulence fetor ex vagina.Cervical cancer there will be different Secondary Symptoms according to involving scope, as frequent micturition, urgent micturition, constipation, lower limb swell and ache late period.
Publication No. CN 104524372 A(application number 201410839328.2) Chinese patent literature disclose a kind of Chinese medicine preparation for the treatment of cervical cancer, it is the granule be made up of following raw material by weight ratio: Rhizoma Atractylodis processed, Radix Gentianae Macrophyllae, Radix Saposhnikoviae, Radix Angelicae Sinensis, Radix Stephaniae Tetrandrae, Herba Artemisiae Scopariae, Cortex Dictamni, Cortex Phellodendri, the Radix Pulsatillae, Radix Sanguisorbae, Fructus Chaenomelis, Flos Lonicerae charcoal, Fructus Aurantii Immaturus, charred Radix Et Rhizoma Rhei, Semen Gleditsiae, Radix Glycyrrhizae uralensis, Radix Notoginseng powder, charred RADIX RUBIAE, Rhizoma Et Radix Notopterygii, Oletum Trogopterori, GAOMU, buckwheat fringe charcoal, Os Sepiae, Fructus Cannabis, Flos Sophorae Immaturus (processed), Semen Pruni, Rhizoma Smilacis Glabrae, Rhizoma Alismatis, Caulis Akebiae, Semen Plantaginis, fresh rehmannia charcoal, Fructus Gardeniae, Pollen Typhae carbon, Scutellaria lateriflora, Polyporus.Publication No. CN 104013925 A(application number 201410300411.2) Chinese patent literature disclose a kind of Chinese medicine of cervical cancer, belong to technical field of Chinese medicines, be made up of the crude drug of following weight: Fructus Aurantii Immaturus 8 grams, Semen Sinapis Albae 8 grams, Radix Stephaniae Tetrandrae 8 grams, 8 grams, Semen Armeniacae Amarum, 10 grams, Pericarpium Citri Reticulatae Viride, the Radix Paeoniae Alba 10 grams, Rhizoma Cyperi 10 grams, Radix Paeoniae Rubra 10 grams, Rhizoma Coptidis 10 grams, 10 grams, Semen Persicae, 15 grams, Poria, Radix Angelicae Sinensis 15 grams, Rhizoma Sparganii 15 grams, Rhizoma Curcumae 15 grams, the Rhizoma Anemarrhenae 15 grams, Endothelium Corneum Gigeriae Galli 20 grams, Cortex Phellodendri 20 grams, Radix Codonopsis 20 grams, Radix Sophorae Tonkinensis 30 grams, Herba Patriniae 30 grams, the Radix Astragali 45 grams, Scorpio 6 grams, Scolopendra 3, 3 grams, Radix Glycyrrhizae.Publication No. CN 103977327 A(application number 201410240184.9) Chinese patent literature disclose a kind of Chinese medicine preparation and preparation method for the treatment of cervical cancer, belong to the field of Chinese medicines; The raw material of Chinese medicine preparation effective ingredient of the present invention consists of: Radix Cynanchi Auriculati, Herba Orchidis Latifoliae, Herba Swertiae heteranthae, Semen Euryales, Fructus Alpiniae Oxyphyllae, Fructus Corni, Squama Manis, Radix Paeoniae Rubra, Folium Malvae, Petiolus nelumbinis, Semen Sinapis Albae, Rhizoma Chuanxiong, Ramulus Et folium Spiraeae Acuminatae, Radix Berchemiae Giraldianae, Herba rhynchosiae volubilis and iron powder.
Though operative treatment can remove lump fast, relapse rate is high, and treatment by Chinese herbs to have side effect little, the advantage that anti-recurrence rate is effective, can stablize the state of an illness, indiffusion, part Chinese medicine formula Clinical Practice, therapeutic effect is poor, therefore needs to work out Be very effective, formula that anti-relapse rate is high.
Summary of the invention
For the problem of prior art, the object of this invention is to provide a kind of Be very effective, take the composition and method of making the same of the wide treatment cervical cancer of safe and applicable.
Technical scheme of the present invention is:
The compositions for the treatment of cervical cancer, is prepared from primarily of following bulk drugs, is mass parts: Herba Scutellariae Barbatae 10-16; Radix Gentianae 8-15; Radix Paeoniae Alba 9-16; Folium Canarii Pimelae 10-13; Herba Limoii Bicoloris 8-14; Radix seu Folium Tetracerae asiaticae 6-13; The blue or green 9-14 in Wangjiang; Caulis Bauhihiae Championii 7-15; Semen Coicis 11-17; Conyza japonica 9-15; Herba Patriniae 7-14; Radix Pulsatillae 6-15; Herba Galii Teneri 10-14; Herba Lactucae Indicae 8-12; Water Impatientis 9-13.
Preferred version is, Herba Scutellariae Barbatae 12-14; Radix Gentianae 10-13; Radix Paeoniae Alba 11-14; Folium Canarii Pimelae 11-12; Herba Limoii Bicoloris 10-12; Radix seu Folium Tetracerae asiaticae 8-11; The blue or green 10-13 in Wangjiang; Caulis Bauhihiae Championii 9-13; Semen Coicis 13-15; Conyza japonica 11-13; Herba Patriniae 9-12; Radix Pulsatillae 8-13; Herba Galii Teneri 11-13; Herba Lactucae Indicae 9-11; Water Impatientis 10-12.
More preferably, Herba Scutellariae Barbatae 13; Radix Gentianae 11.5; The Radix Paeoniae Alba 12.5; Folium Canarii Pimelae 11.5; Herba Limoii Bicoloris 11; Radix seu Folium Tetracerae asiaticae 9.5; Wangjiang green grass or young crops 11.5; Caulis Bauhihiae Championii 11; Semen Coicis 14; Conyza japonica 12; Herba Patriniae 10.5; The Radix Pulsatillae 10.5; Herba Galii Teneri 12; Herba Lactucae Indicae 10; Water Impatientis 11.
The compositions of described treatment cervical cancer, be made into pharmaceutically acceptable unguentum, its preparation method is:
(1) Radix Gentianae, Radix seu Folium Tetracerae asiaticae, Wangjiang green grass or young crops, Caulis Bauhihiae Championii and Herba Lactucae Indicae roguing are cleaned, be placed in non iron container, add soaking in rice vinegar 12 minutes, add boiled crude drug quality 5-7 water doubly (preferred: the water adding boiled crude drug quality 6 times) again to decoct, big fire is boiled, and turns little fire and decocts, after filtration, filtering residue decocts again, merges twice gained filtrate;
(2) get Herba Scutellariae Barbatae, Herba Limoii Bicoloris, Herba Patriniae, Herba Galii Teneri and water Impatientis and clean remove impurity, be cut into thread, it is (preferred: moistening 14-22 minute to be placed in refined honey water moistening 10-26 minute; Be more preferably: moistening 18 minutes), take out, put into frying pan, intense fire is fried to coke black, and drench into clear water, go out most Mars, and taking-up is dried;
(3) get the Radix Paeoniae Alba, Conyza japonica and the Radix Pulsatillae to clean, put into the saline heated and boiled of 30% concentration, after taking-up, be cut into strip, be placed in frying pan, moderate heat stir-fries to surface focal spot, takes out;
(4) get Semen Coicis to clean, removing cot and impurity, is placed in steamer, and Steam by water bath, to well-done, take out, pulverizes, and adds yellow wine and mixes thoroughly, be placed in frying pan together with the Folium Canarii Pimelae only make, and slow fire stir-fries 12-24 minute (preferably: slow fire stir-fries 16-20 minute; Be more preferably: slow fire stir-fries 18 minutes), take out;
(5) pulverized by made to step (2) (3) (4) crude drug, join in step (1) gained filtrate, heating is condensed into thick paste, obtains unguentum.
The preparation method of the compositions unguentum of described treatment cervical cancer, step (1) turns little fire and decocts 26-38 minute (preferably: turn little fire and decoct 30-34 minute; Be more preferably: turn little fire and decoct 32 minutes).
The compositions of described treatment cervical cancer, be made into pharmaceutically acceptable powder, its preparation method is:
(1) Radix Gentianae, Radix seu Folium Tetracerae asiaticae, Wangjiang green grass or young crops, Caulis Bauhihiae Championii and Herba Lactucae Indicae roguing are cleaned, be placed in non iron container, add soaking in rice vinegar 12 minutes, add boiled crude drug quality 5-7 water doubly (preferred: the water adding boiled crude drug quality 6 times) again to decoct, big fire is boiled, and turns little fire and decocts 26-38 minute (preferably: turn little fire and decoct 30-34 minute; Be more preferably: turn little fire and decoct 32 minutes), after filtration, filtering residue decocts again, merges twice gained filtrate;
(2) get Herba Scutellariae Barbatae, Herba Limoii Bicoloris, Herba Patriniae, Herba Galii Teneri and water Impatientis and clean remove impurity, be cut into thread, it is (preferred: moistening 14-22 minute to be placed in refined honey water moistening 10-26 minute; Be more preferably: moistening 18 minutes), take out, put into frying pan, intense fire is fried to coke black, and drench into clear water, go out most Mars, and taking-up is dried;
(3) get the Radix Paeoniae Alba, Conyza japonica and the Radix Pulsatillae to clean, put into the saline heated and boiled of 30% concentration, after taking-up, be cut into strip, be placed in frying pan, moderate heat stir-fries to surface focal spot, takes out;
(4) get Semen Coicis to clean, removing cot and impurity, is placed in steamer, and Steam by water bath, to well-done, take out, pulverizes, and adds yellow wine and mixes thoroughly, be placed in frying pan together with the Folium Canarii Pimelae only make, and slow fire stir-fries 12-24 minute (preferably: slow fire stir-fries 16-20 minute; Be more preferably: slow fire stir-fries 18 minutes), take out;
(5) spray drying step (1) gained filtrate, pulverizes and sieves dry thing, obtains powder together with step (2) (3) (4) made crude drug.
The preparation method of the compositions powder of described treatment cervical cancer, it is (preferred: to pulverize 210-250 mesh sieve that step (5) pulverized 190-270 mesh sieve; Be more preferably: pulverized 230 mesh sieves).
The compositions of described treatment cervical cancer, be made into pharmaceutically acceptable capsule, its preparation method is:
(1) Radix Gentianae, Radix seu Folium Tetracerae asiaticae, Wangjiang green grass or young crops, Caulis Bauhihiae Championii and Herba Lactucae Indicae roguing are cleaned, be placed in non iron container, add soaking in rice vinegar 12 minutes, add boiled crude drug quality 5-7 water doubly (preferred: the water adding boiled crude drug quality 6 times) again to decoct, big fire is boiled, and turns little fire and decocts 26-38 minute (preferably: turn little fire and decoct 30-34 minute; Be more preferably: turn little fire and decoct 32 minutes), after filtration, filtering residue decocts again, merges twice gained filtrate;
(2) get Herba Scutellariae Barbatae, Herba Limoii Bicoloris, Herba Patriniae, Herba Galii Teneri and water Impatientis and clean remove impurity, be cut into thread, it is (preferred: moistening 14-22 minute to be placed in refined honey water moistening 10-26 minute; Be more preferably: moistening 18 minutes), take out, put into frying pan, intense fire is fried to coke black, and drench into clear water, go out most Mars, and taking-up is dried;
(3) get the Radix Paeoniae Alba, Conyza japonica and the Radix Pulsatillae to clean, put into the saline heated and boiled of 30% concentration, after taking-up, be cut into strip, be placed in frying pan, moderate heat stir-fries to surface focal spot, takes out;
(4) get Semen Coicis to clean, removing cot and impurity, is placed in steamer, and Steam by water bath, to well-done, take out, pulverizes, and adds yellow wine and mixes thoroughly, be placed in frying pan together with the Folium Canarii Pimelae only make, and slow fire stir-fries 12-24 minute (preferably: slow fire stir-fries 16-20 minute; Be more preferably: slow fire stir-fries 18 minutes), take out;
(5) spray drying step (1) gained filtrate, pulverized 120 mesh sieves by dry thing, and was packed in capsule, obtains capsule together with step (2) (3) (4) made crude drug.
The preparation method of the composition capsule of described treatment cervical cancer, in the every capsules of step (5), contained medicated powder weight is that 0.25-0.45g(is preferred: in every capsules, contained medicated powder weight is 0.3-0.4g; Be more preferably: in every capsules, contained medicated powder weight is 0.35g).
The compositions of described treatment cervical cancer, be made into pharmaceutically acceptable tablet, its preparation method is:
(1) Radix Gentianae, Radix seu Folium Tetracerae asiaticae, Wangjiang green grass or young crops, Caulis Bauhihiae Championii and Herba Lactucae Indicae roguing are cleaned, be placed in non iron container, add soaking in rice vinegar 12 minutes, add boiled crude drug quality 5-7 water doubly (preferred: the water adding boiled crude drug quality 6 times) again to decoct, big fire is boiled, and turns little fire and decocts, after filtration, filtering residue decocts again, merges twice gained filtrate;
(2) get Herba Scutellariae Barbatae, Herba Limoii Bicoloris, Herba Patriniae, Herba Galii Teneri and water Impatientis and clean remove impurity, be cut into thread, it is (preferred: moistening 14-22 minute to be placed in refined honey water moistening 10-26 minute; Be more preferably: moistening 18 minutes), take out, put into frying pan, intense fire is fried to coke black, and drench into clear water, go out most Mars, and taking-up is dried;
(3) get the Radix Paeoniae Alba, Conyza japonica and the Radix Pulsatillae to clean, put into the saline heated and boiled of 30% concentration, after taking-up, be cut into strip, be placed in frying pan, moderate heat stir-fries to surface focal spot, takes out;
(4) get Semen Coicis to clean, removing cot and impurity, is placed in steamer, and Steam by water bath, to well-done, take out, pulverizes, and adds yellow wine and mixes thoroughly, be placed in frying pan together with the Folium Canarii Pimelae only make, and slow fire stir-fries 12-24 minute (preferably: slow fire stir-fries 16-20 minute; Be more preferably: slow fire stir-fries 18 minutes), take out, pulverized 100 mesh sieves together with step (2) (3) made crude drug;
(5) blend step (1) (4) gained filtrate and medicated powder, heating is concentrated, then adds adjuvant and make soft material, and be pressed through screen cloth, make graininess, dry tabletting, obtains tablet dosage form, obtains tablet.
The preparation method of the composition tablet of described treatment cervical cancer, step (1) turns little fire and decocts 18-26 minute (preferably: turn little fire and decoct 20-24 minute; Be more preferably: turn little fire and decoct 22 minutes).
The composite formula science for the treatment of cervical cancer provided by the invention, preparation method is simple.In addition, its excellent part also shows:
1, products obtained therefrom of the present invention, determined curative effect, can the diffusion of effective anticancer, prevents from recurring again;
2, this formula is summed up through clinical practice for many years and is formed, and has effect of heat-clearing and toxic substances removing, benefiting qi and nourishing blood;
3, Chinese crude drug selected by the present invention, safe non-evident effect, life-time service can improve healthy.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
embodiment 1the compositions for the treatment of cervical cancer, is prepared from (every part of 10g) primarily of following bulk drugs: Herba Scutellariae Barbatae 10 parts, Radix Gentianae 8 parts, the Radix Paeoniae Alba 9 parts, Folium Canarii Pimelae 10 parts, Herba Limoii Bicoloris 8 parts, Radix seu Folium Tetracerae asiaticae 6 parts, blue or green 9 parts of Wangjiang, Caulis Bauhihiae Championii 7 parts, Semen Coicis 11 parts, Conyza japonica 9 parts, Herba Patriniae 7 parts, the Radix Pulsatillae 6 parts, Herba Galii Teneri 10 parts, Herba Lactucae Indicae 8 parts, water Impatientis 9 parts.The preparation method of the compositions unguentum of above-mentioned treatment cervical cancer is:
(1) Radix Gentianae, Radix seu Folium Tetracerae asiaticae, Wangjiang green grass or young crops, Caulis Bauhihiae Championii and Herba Lactucae Indicae roguing are cleaned, be placed in non iron container, add soaking in rice vinegar 12 minutes, add the soak by water of boiled crude drug quality 6 times again, big fire is boiled, and turns little fire and decocts 32 minutes, after filtration, filtering residue decocts again, merges twice gained filtrate;
(2) get Herba Scutellariae Barbatae, Herba Limoii Bicoloris, Herba Patriniae, Herba Galii Teneri and water Impatientis and clean remove impurity, be cut into thread, be placed in refined honey water moistening 18 minutes, take out, put into frying pan, intense fire is fried to coke black, and drench into clear water, go out most Mars, and taking-up is dried;
(3) get the Radix Paeoniae Alba, Conyza japonica and the Radix Pulsatillae to clean, put into the saline heated and boiled of 30% concentration, after taking-up, be cut into strip, be placed in frying pan, moderate heat stir-fries to surface focal spot, takes out;
(4) get Semen Coicis to clean, removing cot and impurity, be placed in steamer, and Steam by water bath, to well-done, take out, pulverizes, and add yellow wine and mix thoroughly together with the clean Folium Canarii Pimelae made, be placed in frying pan, slow fire stir-fries 18 minutes, takes out;
(5) pulverized by made to step (2) (3) (4) crude drug, join in step (1) gained filtrate, heating is condensed into thick paste, obtains unguentum.
embodiment 2the compositions for the treatment of cervical cancer, is prepared from (every part of 10g) primarily of following bulk drugs: Herba Scutellariae Barbatae 16 parts, Radix Gentianae 15 parts, the Radix Paeoniae Alba 16 parts, Folium Canarii Pimelae 13 parts, Herba Limoii Bicoloris 14 parts, Radix seu Folium Tetracerae asiaticae 13 parts, blue or green 14 parts of Wangjiang, Caulis Bauhihiae Championii 15 parts, Semen Coicis 17 parts, Conyza japonica 15 parts, Herba Patriniae 14 parts, the Radix Pulsatillae 15 parts, Herba Galii Teneri 14 parts, Herba Lactucae Indicae 12 parts, water Impatientis 13 parts.The preparation method of the compositions powder of above-mentioned treatment cervical cancer is:
(1) Radix Gentianae, Radix seu Folium Tetracerae asiaticae, Wangjiang green grass or young crops, Caulis Bauhihiae Championii and Herba Lactucae Indicae roguing are cleaned, be placed in non iron container, add soaking in rice vinegar 12 minutes, add the soak by water of boiled crude drug quality 6 times again, big fire is boiled, and turns little fire and decocts 32 minutes, after filtration, filtering residue decocts again, merges twice gained filtrate;
(2) get Herba Scutellariae Barbatae, Herba Limoii Bicoloris, Herba Patriniae, Herba Galii Teneri and water Impatientis and clean remove impurity, be cut into thread, be placed in refined honey water moistening 18 minutes, take out, put into frying pan, intense fire is fried to coke black, and drench into clear water, go out most Mars, and taking-up is dried;
(3) get the Radix Paeoniae Alba, Conyza japonica and the Radix Pulsatillae to clean, put into the saline heated and boiled of 30% concentration, after taking-up, be cut into strip, be placed in frying pan, moderate heat stir-fries to surface focal spot, takes out;
(4) get Semen Coicis to clean, removing cot and impurity, be placed in steamer, and Steam by water bath, to well-done, take out, pulverizes, and add yellow wine and mix thoroughly together with the clean Folium Canarii Pimelae made, be placed in frying pan, slow fire stir-fries 18 minutes, takes out;
(5) spray drying step (1) gained filtrate, pulverized 230 mesh sieves by dry thing, obtained powder together with step (2) (3) (4) made crude drug.
Model case: xxx, women, 33 years old.Main suit: Cervical Contactive Bleeding.Medical history: patient closely over the past half year, has bleeding after sexual intercourse, does not take notice of during beginning, finds that vagina occurred flow liquid without obvious inducement afterwards, and with leucorrhoea grow in quantity, to examination in hospital, find that cervix uteri place has cauliflower-like to swell thing, pathological section is shown as squamous carcinoma of the cervix.
Take this example gained powder, each 2-3g, warm boiled water, one day twice, it within 30 days, is a course for the treatment of, after patient takes a course for the treatment of, bleeding alleviates, and vaginal secretion obviously reduces, after continuing to take two courses for the treatment of, the uncomfortable disease of patient all disappears, and after consolidating a course for the treatment of, patient recovers normal.
embodiment 3the compositions for the treatment of cervical cancer, is prepared from (every part of 10g) primarily of following bulk drugs: Herba Scutellariae Barbatae 12 parts, Radix Gentianae 10 parts, the Radix Paeoniae Alba 11 parts, Folium Canarii Pimelae 11 parts, Herba Limoii Bicoloris 10 parts, Radix seu Folium Tetracerae asiaticae 8 parts, blue or green 10 parts of Wangjiang, Caulis Bauhihiae Championii 9 parts, Semen Coicis 13 parts, Conyza japonica 11 parts, Herba Patriniae 9 parts, the Radix Pulsatillae 8 parts, Herba Galii Teneri 11 parts, Herba Lactucae Indicae 9 parts, water Impatientis 10 parts.The preparation method of the composition capsule of above-mentioned treatment cervical cancer is:
(1) Radix Gentianae, Radix seu Folium Tetracerae asiaticae, Wangjiang green grass or young crops, Caulis Bauhihiae Championii and Herba Lactucae Indicae roguing are cleaned, be placed in non iron container, add soaking in rice vinegar 12 minutes, add the soak by water of boiled crude drug quality 6 times again, big fire is boiled, and turns little fire and decocts 32 minutes, after filtration, filtering residue decocts again, merges twice gained filtrate;
(2) get Herba Scutellariae Barbatae, Herba Limoii Bicoloris, Herba Patriniae, Herba Galii Teneri and water Impatientis and clean remove impurity, be cut into thread, be placed in refined honey water moistening 18 minutes, take out, put into frying pan, intense fire is fried to coke black, and drench into clear water, go out most Mars, and taking-up is dried;
(3) get the Radix Paeoniae Alba, Conyza japonica and the Radix Pulsatillae to clean, put into the saline heated and boiled of 30% concentration, after taking-up, be cut into strip, be placed in frying pan, moderate heat stir-fries to surface focal spot, takes out;
(4) get Semen Coicis to clean, removing cot and impurity, be placed in steamer, and Steam by water bath, to well-done, take out, pulverizes, and add yellow wine and mix thoroughly together with the clean Folium Canarii Pimelae made, be placed in frying pan, slow fire stir-fries 18 minutes, takes out;
(5) spray drying step (1) gained filtrate, pulverized 120 mesh sieves by dry thing, was packed in capsule together with step (2) (3) (4) made crude drug, and in every capsules, contained medicated powder weight is 0.35g, obtains capsule.
Model case: xxx, women, 48 years old.Medical history: patient's menopause, after 1 year, finds abnormal vaginal bleeding, and with lower abdomen pain, secretions increases, vagina abnormal flavour is serious gradually, through examination in hospital, is diagnosed as cervical cancer mid-term, once carried out operative treatment, the state of an illness is not fully recovered always, then finds tcm methods treatment.
Recommend to take this example gained capsule, each 2-3 grain, warm boiled water through people, one day twice, within 30 days, be a course for the treatment of, after patient takes two courses for the treatment of, vaginal secretions alleviates gradually, elimination of off flavor, after continuing two courses for the treatment of of medication, patient recovers normal, and the mental status takes a turn for the better, follow up a case by regular visits to after 1 year, the state of an illness does not recur again.
embodiment 4the compositions for the treatment of cervical cancer, is prepared from (every part of 10g) primarily of following bulk drugs: Herba Scutellariae Barbatae 14 parts, Radix Gentianae 13 parts, the Radix Paeoniae Alba 14 parts, Folium Canarii Pimelae 12 parts, Herba Limoii Bicoloris 12 parts, Radix seu Folium Tetracerae asiaticae 11 parts, blue or green 13 parts of Wangjiang, Caulis Bauhihiae Championii 13 parts, Semen Coicis 15 parts, Conyza japonica 13 parts, Herba Patriniae 12 parts, the Radix Pulsatillae 13 parts, Herba Galii Teneri 13 parts, Herba Lactucae Indicae 11 parts, water Impatientis 12 parts.The preparation method of the composition tablet of above-mentioned treatment cervical cancer is:
(1) Radix Gentianae, Radix seu Folium Tetracerae asiaticae, Wangjiang green grass or young crops, Caulis Bauhihiae Championii and Herba Lactucae Indicae roguing are cleaned, be placed in non iron container, add soaking in rice vinegar 12 minutes, add the soak by water of boiled crude drug quality 6 times again, big fire is boiled, and turns little fire and decocts 22 minutes, after filtration, filtering residue decocts again, merges twice gained filtrate;
(2) get Herba Scutellariae Barbatae, Herba Limoii Bicoloris, Herba Patriniae, Herba Galii Teneri and water Impatientis and clean remove impurity, be cut into thread, be placed in refined honey water moistening 18 minutes, take out, put into frying pan, intense fire is fried to coke black, and drench into clear water, go out most Mars, and taking-up is dried;
(3) get the Radix Paeoniae Alba, Conyza japonica and the Radix Pulsatillae to clean, put into the saline heated and boiled of 30% concentration, after taking-up, be cut into strip, be placed in frying pan, moderate heat stir-fries to surface focal spot, takes out;
(4) get Semen Coicis to clean, removing cot and impurity, be placed in steamer, and Steam by water bath is to well-done, take out, pulverize, add yellow wine and mix thoroughly together with the clean Folium Canarii Pimelae made, be placed in frying pan, slow fire stir-fries 18 minutes, takes out, pulverized 100 mesh sieves together with step (2) (3) made crude drug;
(5) blend step (1) (4) gained filtrate and medicated powder, heating is concentrated, then adds adjuvant and make soft material, and be pressed through screen cloth, make graininess, dry tabletting, obtains tablet dosage form, obtains tablet.
Model case: xxx, women, 31 years old.Main suit: patient occurred colporrhagia without obvious inducement before four months, amount is few, and without clot, leucorrhea quantity is more, without other uncomfortable diseases, patient worries that health goes wrong, and then removes examination in hospital, and cervix uteri is slightly rotten to the corn, quality is comparatively hard, looks into through the blood examination of cervical scraping smear cell, and it is early stage to be finally diagnosed as cervical cancer.
Take this example gained tablet, each 2-3 sheet, warm boiled water, one day twice, within 30 days, be a course for the treatment of, after patient takes a course for the treatment of, colporrhagia basic controlling, after continuing to take a course for the treatment of, the all diseases of patient disappear entirely, check display, and cervix uteri place recovers normal, and patient fully recovers.
embodiment 5the compositions for the treatment of cervical cancer, is prepared from (every part of 10g) primarily of following bulk drugs: Herba Scutellariae Barbatae 13 parts, Radix Gentianae 11.5 parts, the Radix Paeoniae Alba 12.5 parts, Folium Canarii Pimelae 11.5 parts, Herba Limoii Bicoloris 11 parts, Radix seu Folium Tetracerae asiaticae 9.5 parts, blue or green 11.5 parts of Wangjiang, Caulis Bauhihiae Championii 11 parts, Semen Coicis 14 parts, Conyza japonica 12 parts, Herba Patriniae 10.5 parts, the Radix Pulsatillae 10.5 parts, Herba Galii Teneri 12 parts, Herba Lactucae Indicae 10 parts, water Impatientis 11 parts.The preparation method of the compositions unguentum of above-mentioned treatment cervical cancer is:
(1) Radix Gentianae, Radix seu Folium Tetracerae asiaticae, Wangjiang green grass or young crops, Caulis Bauhihiae Championii and Herba Lactucae Indicae roguing are cleaned, be placed in non iron container, add soaking in rice vinegar 12 minutes, add the soak by water of boiled crude drug quality 6 times again, big fire is boiled, and turns little fire and decocts 32 minutes, after filtration, filtering residue decocts again, merges twice gained filtrate;
(2) get Herba Scutellariae Barbatae, Herba Limoii Bicoloris, Herba Patriniae, Herba Galii Teneri and water Impatientis and clean remove impurity, be cut into thread, be placed in refined honey water moistening 18 minutes, take out, put into frying pan, intense fire is fried to coke black, and drench into clear water, go out most Mars, and taking-up is dried;
(3) get the Radix Paeoniae Alba, Conyza japonica and the Radix Pulsatillae to clean, put into the saline heated and boiled of 30% concentration, after taking-up, be cut into strip, be placed in frying pan, moderate heat stir-fries to surface focal spot, takes out;
(4) get Semen Coicis to clean, removing cot and impurity, be placed in steamer, and Steam by water bath, to well-done, take out, pulverizes, and add yellow wine and mix thoroughly together with the clean Folium Canarii Pimelae made, be placed in frying pan, slow fire stir-fries 18 minutes, takes out;
(5) pulverized by made to step (2) (3) (4) crude drug, join in step (1) gained filtrate, heating is condensed into thick paste, obtains unguentum.
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
Herba Scutellariae Barbatae: base is former: be the herb of labiate Herba Scutellariae Barbatae.Chemical analysis: herb is containing alkaloid, flavonoid glycoside, phenols, steroidal.Nature and flavor: pungent are flat.Function cures mainly: heat clearing away, removing toxic substances, dissipating blood stasis, hemostasis, analgesic therapy.Control haematemesis, epistaxis, stranguria with blood, bloody dysentery, jaundice, have sore throat, lung abscess, furuncle, scrofula, sore, cancerous protuberance, traumatic injury knife injury, venom.
Radix Gentianae: base is former: be the dry root and rhizome of gentianaceae plant Gentiana manshurica, Radix Gentianae, G. triflora or Gentiana rigescens Franch.Nature and flavor: bitter, cold.Gui Jing: return liver, gallbladder meridian.Function cures mainly: heat clearing and damp drying, eliminating pathogen in the liver gallbladder fire.For jaundice due to damp-heat, swelling of the vulva pudendal pruritus, leukorrhagia, persistent erection of the penis, eczema pruritus, conjunctival congestion, deaf, hypochondriac pain, bitter taste, convulsion with spasms.
The Radix Paeoniae Alba: base is former: be the root of ranunculaceae plant Radix Paeoniae (cultigen).Nature and flavor with return through, bitter, sour, be slightly cold.Return liver, spleen channel.There is nourishing blood for regulating menstruation, astringing YIN to stop sweating, easing the affected liver to relieve pain, stabilize effect of sun.For blood deficiency and yellow complexion, menoxenia, spontaneous perspiration, night sweat, hypochondriac pain, stomachache, limb pain twin, has a headache dizzy.
Folium Canarii Pimelae: base is former: be the leaf of olive subject plant Fructus Canarii Pimelae.Nature and flavor: micro-hardship; Puckery; Cool in nature.Gui Jing: Liver Channel.Function cures mainly: heat-clearing and toxic substances removing; Hemostasis.Main cold, fever; Cough due to lung-heat; Erysipelas; Furuncle and phyma; Metrorrhagia.
Herba Limoii Bicoloris: base is former: be root or the herb of Plumbaginaceae plant Herba Limoii Bicoloris.Nature and flavor: sweet; Micro-hardship; Slightly warm in nature.Gui Jing: spleen; Liver; Urinary bladder channel.Function cures mainly: benefiting QI and nourishing blood; Dissipating blood stasis stops blooding.Main weak after being ill; Gastric abscess; Dyspepsia; Menoxenia, metrorrhagia; Leukorrhagia; Hematuria; Hemorrhoidal bleeding.
Radix seu Folium Tetracerae asiaticae: base is former: be root or the stem and leaf of rattan when Dilleniaceae plant Radix seu Folium Tetracerae asiaticae and row leaf stannum.Nature and flavor: acid; Puckery; Flat.Gui Jing: liver; Large intestine channel.Function cures mainly: arresting collape syndrome by astringents; Reducing swelling and alleviating pain.Main chronic diarrhea chronic dysentery; Have blood in stool; Proctoptosis; Seminal emission; Leucorrhea; Uterine prolapse; Treating swelling and pain by traumatic injury.
Wangjiang is blue or green: base is former: be root or the herb of labiate Stachys palustris L..Nature and flavor: sweet in the mouth; Bitter; Cool in nature.Gui Jing: lung meridian.Function cures mainly: heat-clearing and toxic substances removing; Removing heat from blood and promoting blood circulation.Main laryngopharynx swelling and pain; Lung abscess; Pertussis; Dysentery; Acute mastitis; Herpes zoster; The raw cataracta of order; Spitting of blood; Treating swelling and pain by traumatic injury.
Caulis Bauhihiae Championii: base is former: be root or the stem of leguminous plant Caulis Bauhiniae Championii.Nature and flavor: earnestly; Flat; Nontoxic.Gui Jing: liver; Kidney channel.Function cures mainly: expelling wind and removing dampness, promoting flow of QI and blood.Main air pain of dampness syndrome, traumatic injury, hemiplegia, gastric abscess, infantile malnutrition, dysentery.
Semen Coicis: base is former: be the kernel of grass Semen Coicis.Chemical analysis: kernel contains protein 16.2%, fat 4.65%, carbohydrate 79.17%, a small amount of vitamin B1 (330 microgram %).Seed is containing aminoacid (for leucine, lysine, arginine, tyrosine etc.), Coixol, Coixenolide, triterpenoid.Nature and flavor: sweet light, cool.Gui Jing: enter spleen, lung, kidney channel.Function cures mainly: spleen invigorating, tonifying the lung, heat clearing away, dampness removing.Control and have loose bowels, arthralgia chiefly caused by damp pathogen, the contracture of muscle arteries and veins, joint stuffiness, edema, beriberi, consumptive lung disease, lung abscess, acute appendicitis, stranguria with turbid discharge, leucorrhea.
Conyza japonica: base is former: be the root of feverfew Conyza japonica.Nature and flavor: pungent, micro-hardship are flat.Function cures mainly: anti-inflammatory analgesic, dispelling pathogenic wind and eliminating phlegm.Cure mainly pleuritis, infantile pneumonia, laryngitis, infantile convulsion.
Herba Patriniae: base is former: be the herb of Valerianaceae plant Patrinia scabiosaefolia Fisch and patrima villosa.Nature and flavor: acrid in the mouth; Bitter; Cold nature.Gui Jing: return rib; Large intestine; Liver Channel.Function cures mainly: heat-clearing and toxic substances removing; To invigorate blood circulation evacuation of pus.Main intestinal carbuncle; Lung abscess; Carbuncle; Dysentery; The stagnant stomachache of the stasis of blood in puerperal.
The Radix Pulsatillae: base is former: be the root of the ranunculaceae plant Radix Pulsatillae.Nature and flavor with return through: bitter, cold.Return stomach, large intestine channel.Function with cure mainly: heat-clearing and toxic substances removing, eliminating pathogenic heat from blood to cure dysentery.For toxic-heat and blood stasis, pudendal pruritus leukorrhagia.
Herba Galii Teneri: base is former: for dicotyledon medicine Maguireothamnus speciosus draws the herb of rattan or thick Ye Lala rattan.Nature and flavor: acrid in the mouth; Micro-hardship; Cold nature.Gui Jing: few cloudy; Taiyin channels.Function cures mainly: heat-clearing and toxic substances removing; Inducing diuresis for treating stranguria syndrome; Reducing swelling and alleviating pain.Main swollen ulcer drug; Mastitis; Appendicitis; Edema; Cold, fever; Dysentery; Urinary tract infection; Hematuria; Gingival hemorrhage; Knife injury is hemorrhage.
Herba Lactucae Indicae: base is former: be herb or the root of feverfew Herba Lactucae Indicae.Nature and flavor: bitter in the mouth; Cold in nature.Function cures mainly: heat-clearing and toxic substances removing; Invigorate blood circulation; Hemostasis.Main laryngopharynx swelling and pain; Intestinal carbuncle; Furuncle toxic swelling; Cervicitis; Postnatal blood stasis raw meat pain; Wart tumor; Metrorrhagia; Bleeding hemorrhoids.
Water Impatientis: base is former: be the herb of Balsaminaceae plant Herba Impatientis Chinensis flower.Nature and flavor: bitter in the mouth, Xin Xingping.Function cures mainly: heat-clearing and toxic substances removing, promoting blood circulation to remove blood stasis, eliminating carbuncle of drawing out the pus.Main infantile pneumonia, laryngopharynx swelling and pain, hematodiarrhoea, snake head-like infection, carbuncle pyogenic infections from tumour or sore, lung is tied.
test example 1the clinical practice of the compositions (embodiment 5) of gained treatment cervical cancer of the present invention:
Choose crowd: in March ,-2015 in May, 2014, according to medical case history, be diagnosed as patient 338 example of cervical cancer six hospitals' screenings, age 39-58 year, 45.2 ± 2.8 years old mean age.
Before test, patient is divided into two groups at random, experimental group 216 example and matched group 122 routine, two groups in age, the course of disease, the state of an illness etc. without significant difference.Matched group adopts radiotherapy means, and experimental group, on the basis of radiotherapy, takes products obtained therefrom of the present invention, each 3-6g, one day twice, warm boiled water, within 30 days, is a course for the treatment of.Treatments period carries out Continuous Observation to two groups of patients, record symptom and change.
Curative effect determinate standard: reference literature criterion of therapeutical effect, (1) complete incidence graph (CR): all pathological changes disappear completely and continue more than 4 weeks; (2) partial rcsponse (PR): tumor focus maximum perpendicular two footpath product reduces >=and 50%, and maintain more than 4 weeks; (3) stable (SD): tumor regression or increase be not all more than 50%; (4) be in progress (PD): tumor focus increases above 50%, or occurs new focus.Effective percentage=(CR+PR)/(CR+PR+SD+PD) * 100%
Clinical effectiveness: after the treatment of three courses for the treatment of, the therapeutic outcome of two groups is as shown in table 1:
As shown in Table 1, the effective percentage of experimental group is 86.6%, and the effective percentage 73.0% of matched group, be starkly lower than the therapeutic effect of experimental group, illustrate that products obtained therefrom of the present invention is evident in efficacy, effectively can suppress cervical cancer, prevent the state of an illness from spreading.
The Chinese medicine used in the present invention, comprise the Herba Scutellariae Barbatae of dissipating blood stasis hemostasis, water Impatientis, the Radix Gentianae of heat clearing and damp drying, the Radix Paeoniae Alba of nourishing blood for regulating menstruation, the Folium Canarii Pimelae of heat-clearing and toxic substances removing, Herba Lactucae Indicae, the Herba Limoii Bicoloris of benefiting QI and nourishing blood, the Radix seu Folium Tetracerae asiaticae of reducing swelling and alleviating pain, Herba Galii Teneri, Wangjiang of removing heat from blood and promoting blood circulation is blue or green, the Caulis Bauhihiae Championii of promoting flow of QI and blood, the Semen Coicis of strengthening the spleen and tonifying the lung, the Conyza japonica of anti-inflammatory analgesic, the Herba Patriniae of evacuation of pus of invigorating blood circulation, the Radix Pulsatillae of eliminating pathogenic heat from blood to cure dysentery, multiple medical material synergism, plays effect of heat-clearing and toxic substances removing, promoting blood circulation and stopping pain, vigorate qi and replenish the blood altogether.
It should be pointed out that detailed description of the invention is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clear and definite disclosed or according to undoubted the obtaining of the written description of file, the claimed scope of this patent all should be thought.
Claims (10)
1. treat the compositions of cervical cancer, it is characterized in that, be prepared from primarily of following bulk drugs, be mass parts: Herba Scutellariae Barbatae 10-16; Radix Gentianae 8-15; Radix Paeoniae Alba 9-16; Folium Canarii Pimelae 10-13; Herba Limoii Bicoloris 8-14; Radix seu Folium Tetracerae asiaticae 6-13; The blue or green 9-14 in Wangjiang; Caulis Bauhihiae Championii 7-15; Semen Coicis 11-17; Conyza japonica 9-15; Herba Patriniae 7-14; Radix Pulsatillae 6-15; Herba Galii Teneri 10-14; Herba Lactucae Indicae 8-12; Water Impatientis 9-13.
2. the compositions for the treatment of cervical cancer as claimed in claim 1, is characterized in that, Herba Scutellariae Barbatae 12-14; Radix Gentianae 10-13; Radix Paeoniae Alba 11-14; Folium Canarii Pimelae 11-12; Herba Limoii Bicoloris 10-12; Radix seu Folium Tetracerae asiaticae 8-11; The blue or green 10-13 in Wangjiang; Caulis Bauhihiae Championii 9-13; Semen Coicis 13-15; Conyza japonica 11-13; Herba Patriniae 9-12; Radix Pulsatillae 8-13; Herba Galii Teneri 11-13; Herba Lactucae Indicae 9-11; Water Impatientis 10-12(is preferably: Herba Scutellariae Barbatae 13; Radix Gentianae 11.5; The Radix Paeoniae Alba 12.5; Folium Canarii Pimelae 11.5; Herba Limoii Bicoloris 11; Radix seu Folium Tetracerae asiaticae 9.5; Wangjiang green grass or young crops 11.5; Caulis Bauhihiae Championii 11; Semen Coicis 14; Conyza japonica 12; Herba Patriniae 10.5; The Radix Pulsatillae 10.5; Herba Galii Teneri 12; Herba Lactucae Indicae 10; Water Impatientis 11).
3. the compositions of the treatment cervical cancer as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable unguentum, its preparation method is:
(1) Radix Gentianae, Radix seu Folium Tetracerae asiaticae, Wangjiang green grass or young crops, Caulis Bauhihiae Championii and Herba Lactucae Indicae roguing are cleaned, be placed in non iron container, add soaking in rice vinegar 12 minutes, add boiled crude drug quality 5-7 water doubly (preferred: the water adding boiled crude drug quality 6 times) again to decoct, big fire is boiled, and turns little fire and decocts, after filtration, filtering residue decocts again, merges twice gained filtrate;
(2) get Herba Scutellariae Barbatae, Herba Limoii Bicoloris, Herba Patriniae, Herba Galii Teneri and water Impatientis and clean remove impurity, be cut into thread, it is (preferred: moistening 14-22 minute to be placed in refined honey water moistening 10-26 minute; Be more preferably: moistening 18 minutes), take out, put into frying pan, intense fire is fried to coke black, and drench into clear water, go out most Mars, and taking-up is dried;
(3) get the Radix Paeoniae Alba, Conyza japonica and the Radix Pulsatillae to clean, put into the saline heated and boiled of 30% concentration, after taking-up, be cut into strip, be placed in frying pan, moderate heat stir-fries to surface focal spot, takes out;
(4) get Semen Coicis to clean, removing cot and impurity, is placed in steamer, and Steam by water bath, to well-done, take out, pulverizes, and adds yellow wine and mixes thoroughly, be placed in frying pan together with the Folium Canarii Pimelae only make, and slow fire stir-fries 12-24 minute (preferably: slow fire stir-fries 16-20 minute; Be more preferably: slow fire stir-fries 18 minutes), take out;
(5) pulverized by made to step (2) (3) (4) crude drug, join in step (1) gained filtrate, heating is condensed into thick paste, obtains unguentum.
4. the preparation method of the compositions unguentum for the treatment of cervical cancer as claimed in claim 3, is characterized in that, it is (preferred: to turn little fire and decoct 30-34 minute that step (1) turns little fire decoction 26-38 minute; Be more preferably: turn little fire and decoct 32 minutes).
5. the compositions of the treatment cervical cancer as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable powder, its preparation method is:
(1) Radix Gentianae, Radix seu Folium Tetracerae asiaticae, Wangjiang green grass or young crops, Caulis Bauhihiae Championii and Herba Lactucae Indicae roguing are cleaned, be placed in non iron container, add soaking in rice vinegar 12 minutes, add boiled crude drug quality 5-7 water doubly (preferred: the water adding boiled crude drug quality 6 times) again to decoct, big fire is boiled, and turns little fire and decocts 26-38 minute (preferably: turn little fire and decoct 30-34 minute; Be more preferably: turn little fire and decoct 32 minutes), after filtration, filtering residue decocts again, merges twice gained filtrate;
(2) get Herba Scutellariae Barbatae, Herba Limoii Bicoloris, Herba Patriniae, Herba Galii Teneri and water Impatientis and clean remove impurity, be cut into thread, it is (preferred: moistening 14-22 minute to be placed in refined honey water moistening 10-26 minute; Be more preferably: moistening 18 minutes), take out, put into frying pan, intense fire is fried to coke black, and drench into clear water, go out most Mars, and taking-up is dried;
(3) get the Radix Paeoniae Alba, Conyza japonica and the Radix Pulsatillae to clean, put into the saline heated and boiled of 30% concentration, after taking-up, be cut into strip, be placed in frying pan, moderate heat stir-fries to surface focal spot, takes out;
(4) get Semen Coicis to clean, removing cot and impurity, is placed in steamer, and Steam by water bath, to well-done, take out, pulverizes, and adds yellow wine and mixes thoroughly, be placed in frying pan together with the Folium Canarii Pimelae only make, and slow fire stir-fries 12-24 minute (preferably: slow fire stir-fries 16-20 minute; Be more preferably: slow fire stir-fries 18 minutes), take out;
(5) spray drying step (1) gained filtrate, pulverizes and sieves dry thing, obtains powder together with step (2) (3) (4) made crude drug.
6. the preparation method of the compositions powder for the treatment of cervical cancer as claimed in claim 5, it is characterized in that, it is (preferred: to pulverize 210-250 mesh sieve that step (5) pulverized 190-270 mesh sieve; Be more preferably: pulverized 230 mesh sieves).
7. the compositions of the treatment cervical cancer as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable capsule, its preparation method is:
(1) Radix Gentianae, Radix seu Folium Tetracerae asiaticae, Wangjiang green grass or young crops, Caulis Bauhihiae Championii and Herba Lactucae Indicae roguing are cleaned, be placed in non iron container, add soaking in rice vinegar 12 minutes, add boiled crude drug quality 5-7 water doubly (preferred: the water adding boiled crude drug quality 6 times) again to decoct, big fire is boiled, and turns little fire and decocts 26-38 minute (preferably: turn little fire and decoct 30-34 minute; Be more preferably: turn little fire and decoct 32 minutes), after filtration, filtering residue decocts again, merges twice gained filtrate;
(2) get Herba Scutellariae Barbatae, Herba Limoii Bicoloris, Herba Patriniae, Herba Galii Teneri and water Impatientis and clean remove impurity, be cut into thread, it is (preferred: moistening 14-22 minute to be placed in refined honey water moistening 10-26 minute; Be more preferably: moistening 18 minutes), take out, put into frying pan, intense fire is fried to coke black, and drench into clear water, go out most Mars, and taking-up is dried;
(3) get the Radix Paeoniae Alba, Conyza japonica and the Radix Pulsatillae to clean, put into the saline heated and boiled of 30% concentration, after taking-up, be cut into strip, be placed in frying pan, moderate heat stir-fries to surface focal spot, takes out;
(4) get Semen Coicis to clean, removing cot and impurity, is placed in steamer, and Steam by water bath, to well-done, take out, pulverizes, and adds yellow wine and mixes thoroughly, be placed in frying pan together with the Folium Canarii Pimelae only make, and slow fire stir-fries 12-24 minute (preferably: slow fire stir-fries 16-20 minute; Be more preferably: slow fire stir-fries 18 minutes), take out;
(5) spray drying step (1) gained filtrate, pulverized 120 mesh sieves by dry thing, and was packed in capsule, obtains capsule together with step (2) (3) (4) made crude drug.
8. the preparation method of the composition capsule for the treatment of cervical cancer as claimed in claim 7, is characterized in that, in the every capsules of step (5), contained medicated powder weight is that 0.25-0.45g(is preferred: in every capsules, contained medicated powder weight is 0.3-0.4g; Be more preferably: in every capsules, contained medicated powder weight is 0.35g).
9. the compositions of the treatment cervical cancer as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable tablet, its preparation method is:
(1) Radix Gentianae, Radix seu Folium Tetracerae asiaticae, Wangjiang green grass or young crops, Caulis Bauhihiae Championii and Herba Lactucae Indicae roguing are cleaned, be placed in non iron container, add soaking in rice vinegar 12 minutes, add boiled crude drug quality 5-7 water doubly (preferred: the water adding boiled crude drug quality 6 times) again to decoct, big fire is boiled, and turns little fire and decocts, after filtration, filtering residue decocts again, merges twice gained filtrate;
(2) get Herba Scutellariae Barbatae, Herba Limoii Bicoloris, Herba Patriniae, Herba Galii Teneri and water Impatientis and clean remove impurity, be cut into thread, it is (preferred: moistening 14-22 minute to be placed in refined honey water moistening 10-26 minute; Be more preferably: moistening 18 minutes), take out, put into frying pan, intense fire is fried to coke black, and drench into clear water, go out most Mars, and taking-up is dried;
(3) get the Radix Paeoniae Alba, Conyza japonica and the Radix Pulsatillae to clean, put into the saline heated and boiled of 30% concentration, after taking-up, be cut into strip, be placed in frying pan, moderate heat stir-fries to surface focal spot, takes out;
(4) get Semen Coicis to clean, removing cot and impurity, is placed in steamer, and Steam by water bath, to well-done, take out, pulverizes, and adds yellow wine and mixes thoroughly, be placed in frying pan together with the Folium Canarii Pimelae only make, and slow fire stir-fries 12-24 minute (preferably: slow fire stir-fries 16-20 minute; Be more preferably: slow fire stir-fries 18 minutes), take out, pulverized 100 mesh sieves together with step (2) (3) made crude drug;
(5) blend step (1) (4) gained filtrate and medicated powder, heating is concentrated, then adds adjuvant and make soft material, and be pressed through screen cloth, make graininess, dry tabletting, obtains tablet dosage form, obtains tablet.
10. the preparation method of the composition tablet for the treatment of cervical cancer as claimed in claim 9, is characterized in that, it is (preferred: to turn little fire and decoct 20-24 minute that step (1) turns little fire decoction 18-26 minute; Be more preferably: turn little fire and decoct 22 minutes).
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Address after: 744300, Gansu Province, Dingxi District, Liberty Street, No. 54 Wen Yuan District, building 2, 1-202 Applicant after: Li Rongqin Address before: Kang Hong Lu 250000 Shandong province Ji'nan city high tech Development Zone No. 758 Applicant before: Li Rongqin |
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