CN103316252A - Traditional Chinese medicine for treating liver fibrosis - Google Patents
Traditional Chinese medicine for treating liver fibrosis Download PDFInfo
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Abstract
The invention relates to a traditional Chinese medicine for treating liver fibrosis. The traditional Chinese medicine is prepared from the following crude drugs in parts by weight: 12 parts of urena procumbens, 14 parts of pavettahongkongensis, 12 parts of root of coix lacryma-jobi ma-yuen, 10 parts of largeleaf violet herb, 9 parts of rock orchid, 8 parts of alpine swertia, 8 parts of orixa japonica, 8 parts of cynanchum auriculatum royle, 14 parts of vermiculate thamnolia thallus, 12 parts of anderson cirrhopetalum herb, 10 parts of tiarella polyphylla, 14 parts of wight parnassia herb, 12 parts of panax bipinnatifidus seem, 10 parts of japanese creeper, 12 parts of thorn pear, 12 parts of wedelia chinensis, 14 parts of rock balls, 12 parts of pilea cavaleriei, and 12 parts of stink wellington. A clinical experiment shows that the traditional Chinese medicine can safely and effectively treat the liver fibrosis.
Description
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine for the treatment of hepatic fibrosis.
Background technology
Hepatic fibrosis refers to by connective tissue paraplasm in the liver due to the various virulence factors, it is not an independently disease to cause the excessive pathological process that precipitates of the interior diffusivity extracellular matrix of liver, but many chronic hepatic diseases all can cause hepatic fibrosis, generally can both cure with chemical fibre soothing liver-QI side.Its cause of disease is broadly divided into infectivity (chronic type b, the third type and hepatitis D, blood draws parasitosis etc.), inborn errors of metabolism (hepatolenticular degeneration, hemachromatosis, α1-antitrypsin deficiency etc.) and chemical metabolization defective (chronic alcoholic liver disease, chronic drug-induced liver disease) and autoimmune hepatitis, Primary Hepatic juice liver cirrhosis and primary sclerosing cholangitis etc.
Still lack at present the effective medicine of generally recognized as safe for hepatic fibrosis.
The present Research of the related medical material of Chinese medicine of the present invention is as follows:
Radix Phyllanthi cochinchinensis [source] Malvaceae Herba urenae procumbentis platymiscium Herba urenae procumbentis Urena procumbens L. is used as medicine with root and leaf.Uproot autumn, and chopping is cleaned in the picking leaves of autumn in summer, dries.[function cures mainly] expelling wind and removing dampness, heat-clearing and toxic substances removing.Be used for flu, rheumatic arthritis, enteritis, dysentery, cough due to lung-heat; Traumatic injury is controlled in external, sore swollen toxin, venom.
Caulis et Folium Pavettae Hongkongensis [source] Rubiaceae Pavetta plant Caulis et folium pavettae hongkongensis Pavetta hongkongensis Brem. is used as medicine with Herb, root, leaf.The four seasons can adopt, and root, leaf philosophy are dried.[function cures mainly] clearing away summer-heat, blood circulation promoting and blood stasis dispelling.Be used for heatstroke, cold, fever, hepatitis, traumatic injury.
Radix Coicis [source] grass family Coix plant Semen Coicis Coix lachrymajobi L. is used as medicine with root and root stock.The root of gathering autumn dries.[function cures mainly] heat clearing away, dampness removing, parasite killing.Be used for urinary tract infection, lithangiuria, edema, beriberi, ascariasis, leukorrhagia.
Herba Violae diamantiacae [source] is Violaceae Viola plant Da Ye common violet Viola diamantiaca Nakai, with all herbal medicine.Gather late summer, cleans, and dries.[function cures mainly] heat-clearing and toxic substances removing, hemostasis.Be used for the furuncle toxic swelling, hordeolum, venom, traumatic hemorrhage.
Lan Huashi ginseng [source] campanulaceae campanula southwest Canterburybells Campanula colorata Wall. is used as medicine with root.Xia Qiu gathers, and cleans and dries or using fresh herb.[function cures mainly] dispels the wind, dampness removing, hemostasis.Be used for rheumatic arthritis, tetanus, hemoptysis of pulmonary tuberculosis.
The whole herb with root of Herba Swertiae heteranthae [source] Gentianaceae Swertia plant Herba Swertiae heteranthae Swertia heterantha Ling.Excavate autumn, cleans and dry.[function cures mainly] suppressing the hyperactive liver, heart tonifying, nourishing blood for regulating menstruation.Be used for blood deficiency dizzy, neurasthenia, vascular hypertension, menoxenia.
The smelly Radix Dichroae Orixa of the smelly Dichroa L. plant of smelly Radix Dichroae [source] Rutaceae japonica Thunb. is used as medicine with root, stem, leaf.Root, the stem four seasons can adopt, and dry; Ye Xiaqiu gathers, using fresh herb.[function cures mainly] clearing away heat-damp and promoting diuresis, preventing the attack (or recurrence) of malaria, pain relieving is calmed the nerves.Be used for anemopyretic cold, Fengshi Guanjie swells and ache, stomachache, malaria, traumatic injury, neurasthenia; Carbuncle sore tumefacting virus is controlled in external.
Caulis et Folium Cynanchi Auriculati [source] is trailing plants rattan section Cynanchum plant Caulis et Folium Cynanchi Auriculati (cynanchum auriculatum Royle) Cynanchum auriculatum Royle exWight, with root or all herbal medicine.[function cures mainly] stomach invigorating removing food stagnancy, removing toxic substances and promoting subsidence of swelling.Be used for abdominal pain due to retention of food, stomachache, infantile malnutrition, dysentery; Venom is controlled in external, furuncle.
Thamnolia vermicularis (Ach.) Asa-hina [source] lichens ground Theaceae Herba Ardisiae Japonicae platymiscium snowfield tea is used as medicine with thallus.The four seasons can adopt, and decontamination dries.[function cures mainly] heat clearing away is calmed the nerves.Be used for heatstroke, dysphoria with smothery sensation in the heart, deficiency of YIN hectic fever, cough due to lung-heat, neurasthenia, hypertension.
The blue Cirrhopetalnm andersonii of Herba Cirrohopetali Andersonii [source] the orchid family volume lobe epidendrum comb medicated cap volume lobe Hook.f. is with all herbal medicine.The four seasons can adopt, using fresh herb or dry.[function cures mainly] expelling wind and removing dampness is invigorated blood circulation, and cough-relieving helps digestion long-pending.Be used for traumatic injury, human female is empty, infantile cough, pertussis.
Herba tiarellae polyphyllae [source] Saxifragaceae Herba tiarellae polyphyllae platymiscium Herba tiarellae polyphyllae Tiarella polyphylla D.Don is with all herbal medicine.Xia Qiu gathers, and dries.[function cures mainly] heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain.Be used for carbuncle furuncle and phyma poison, traumatic injury, hepatitis, cough and asthma.
Herba Parnassiae Wightianae [source] is that brave otology Parnassia plant clavus Herba parnassiae Parnassia wightiana Wall. is with all herbal medicine.Xia Qiu gathers herb, cleans and dries.[function cures mainly] clearing away lung-heat to relieve cough, the diuretic damp eliminating.Be used for the chronic cough spitting of blood, malaria, renal calculus, cholelithiasis, leucorrhea, traumatic injury; Damp and hot sore is controlled in external.
Rhizoma Panacis bipinnatifidi [source] is araliaceae ginseng plant's Rhizoma Panacis bipinnatifidi Panax bipinnatifidus Seem., is used as medicine with root stock.Autumn end excavates, clean dry for subsequent use.[function cures mainly] strengthening by means of tonics, eliminating stasis to stop pain, hemostasis.Be used for weak after being ill, hemoptysis of pulmonary tuberculosis, epistaxis, amenorrhea, puerperal abdominal pain due to blood stasis, arthralgia due to cold-dampnes, traumatic injury.
Hang rock wind [source] Vitaceae Parthenocissus plant different leaf parthenocissus Parthenocissus heterophyllus (Blume) Merr., be used as medicine with root, stem.Adopt autumn, cleans section, dries.[function cures mainly] dispelling, collateral-activating, promoting blood circulation and stopping pain.Be used for bones and muscles pain due to rheumatism, leucorrhea with red and white discharge, puerperal abdonimal pain; Fracture is controlled in external, treating swelling and pain by traumatic injury, furuncle.
Thorn pear [source] Rosaceae gul Fructus Rosae Normalis Rosa roxburghii Tratt. is used as medicine with root and fruit.The fruit picking in summer, uproot autumn, dries or using fresh herb.[function cures mainly] root: digestion-promoting spleen-invigorating, astringing to arrest diarrhea.Be used for dyspeptic abdominal distention, dysentery, enteritis, spontaneous sweating, seminal emission, leucorrhea, menorrhagia, bleeding hemorrhoids.Really: expelling summer-heat helps digestion.Control vitamin C deficiency.
Herbia Wedeliae [source] Compositae Herbia Wedeliae platymiscium Herbia Wedeliae Wedelia chinensis Merr. is with all herbal medicine.Xia Qiu gathers, and cleans using fresh herb or dry.[function cures mainly] heat-clearing and toxic substances removing, preventing phlegm from forming and stopping coughing, removing heat from blood suppressing the hyperactive liver.Be used for the prevention measles, cold, fever, diphtheria, pharyngolaryngitis, tonsillitis, bronchitis, pneumonia, pertussis, spitting of blood, hypertension; The furuncle furuncle and phyma is controlled in external.
Radix Bischofiae Javanicae [source] Begoniaceae Begonia plant pubescence Flos Begoniae Evansianae Begonia henryi Hemsl. is used as medicine with tuber.Take tuber after autumn, clean and dry or using fresh herb.[function cures mainly] detoxifcation, dissipating blood stasis, hemostasis.Be used for traumatic injury, lyssodexis redly collapses leucorrhea; Fracture is controlled in external.
Herba Pileae Cavaleriei [source] Urticaceae Pilea plant ripple edge Rhizoma Belamcandae Pilea cavaleriei Levl. is with all herbal medicine.Can adopt the whole year, using fresh herb or dry.[function cures mainly] heat-clearing and toxic substances removing, nourishing the lung to arrest cough, reducing swelling and alleviating pain.Be used for the cough due to lung-heat, pulmonary tuberculosis, oedema due to nephritis; Traumatic injury is controlled in external, burn and scald, furuncle toxic swelling.
Smelly Wheeling [source] Compositae Genus Saussurea plant cotton wool hieracioides Saussurea lanuginosa Vant. is used as medicine with root.Xia Qiu gathers, and clean chopping is dried.[function cures mainly] nourishing the lung to arrest cough, the detoxifcation pain relieving.Be used for pulmonary tuberculosis, bronchitis, spitting of blood, migraine; Lyssodexis is controlled in external.
Summary of the invention
The present invention aims to provide a kind of Chinese medicine for the treatment of hepatic fibrosis, by selecting suitable medical material and proportioning thereof, reaches the purpose of safe and effective healing hepatic fibrosis.
In order to achieve the above object, the present invention is by the following technical solutions:
A kind of Chinese medicine for the treatment of hepatic fibrosis, it is characterized in that, be prepared from by the medical material of following weight proportion: 12 parts of Radix Phyllanthi cochinchinensiss, 14 parts of Caulis et Folium Pavettae Hongkongensis, 12 parts of Radix Coicis, 10 parts of Herba Violae diamantiacaes, 9 parts of Lan Huashi ginsengs, 8 parts of Herba Swertiae heteranthaes, 8 parts of smelly Radix Dichroaes, 8 parts of Caulis et Folium Cynanchi Auriculati, 14 parts of Thamnolia vermicularis (Ach.) Asa-hina, 12 parts of Herba Cirrohopetali Andersoniis, 10 parts of Herba tiarellae polyphyllaes, 14 parts of Herba Parnassiae Wightianaes, 12 parts of Rhizoma Panacis bipinnatifidis, hang 10 parts of rock wind, 12 parts in pear of thorn, 12 parts of Herbia Wedeliaes, 14 parts of Radix Bischofiae Javanicae, 12 parts of Herba Pileae Cavalerieis, 12 parts of smelly Wheelings.
Below in conjunction with clinical experiment data declaration beneficial effect of the present invention:
1, physical data
Inventor's in December, 2008-2011 is collected the out-patient of 260 routine hepatic fibrosis, age 19-58 year, course of disease 1-7 altogether between year January.Be divided at random: treatment group 200 examples, blank group 60 examples.The data there was no significant differences such as two groups of ages, the state of an illness have comparability.
2, test method
2.1 the capsule that the oral the present invention for the treatment of group makes according to specific embodiment 1, sooner or later respectively once.15 days courses for the treatment of.
2.2 blank group oral placebo capsule, sooner or later respectively once.15 days courses for the treatment of.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
Recovery from illness: clinical symptoms all disappears, and the test chamber inspection is normal.Take a turn for the better: clinical symptom relief, the state of an illness is controlled, and lab testing improves or is normal.Invalid: clinical symptoms is without being clearly better or increasing the weight of.
3.2 treatment statistical result sees Table 1.
Table 1 liang group curative effect relatively
| Group | n | Recovery from illness | Take a turn for the better | Invalid | Total effective rate (%) |
| Treatment group | 200 | 20(10％) | 135(67.5％) | 45(22.5％) | 77.5％ |
| Blank group | 60 | 0 | 6(10％) | 50(90％) | 10％ |
As seen, the medicine that makes of the present invention can safe and effective treating the liver fibrosis.
The specific embodiment
In order to understand better and to implement the present invention, further specify the present invention below in conjunction with specific embodiment.
Specific embodiment 1
Take by weighing: Radix Phyllanthi cochinchinensis 12 gram, Caulis et Folium Pavettae Hongkongensis 14 grams, Radix Coicis 12 grams, Herba Violae diamantiacae 10 grams, Lan Huashi ginseng 9 grams, Herba Swertiae heteranthae 8 grams, smelly Radix Dichroae 8 grams, Caulis et Folium Cynanchi Auriculati 8 grams, Thamnolia vermicularis (Ach.) Asa-hina 14 grams, Herba Cirrohopetali Andersonii 12 grams, Herba tiarellae polyphyllae 10 grams, Herba Parnassiae Wightianae 14 grams, Rhizoma Panacis bipinnatifidi 12 grams, hang rock wind 10 grams, thorn pear 12 grams, Herbia Wedeliae 12 grams, Radix Bischofiae Javanicae 14 grams, Herba Pileae Cavaleriei 12 grams, smelly Wheeling 12 grams, add 8 times of water gagings, decocted 1.5 hours, and filtered; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, drying incapsulates shell, namely gets the capsule that meets 1 day consumption of normal adult.
Be used for the treatment of hepatic fibrosis.Oral, every bu is taken for twice sooner or later.
Specific embodiment 2
Take by weighing: Radix Phyllanthi cochinchinensis 12 gram, Caulis et Folium Pavettae Hongkongensis 14 grams, Radix Coicis 12 grams, Herba Violae diamantiacae 10 grams, Lan Huashi ginseng 9 grams, Herba Swertiae heteranthae 8 grams, smelly Radix Dichroae 8 grams, Caulis et Folium Cynanchi Auriculati 8 grams, Thamnolia vermicularis (Ach.) Asa-hina 14 grams, Herba Cirrohopetali Andersonii 12 grams, Herba tiarellae polyphyllae 10 grams, Herba Parnassiae Wightianae 14 grams, Rhizoma Panacis bipinnatifidi 12 grams, hang rock wind 10 grams, thorn pear 12 grams, Herbia Wedeliae 12 grams, Radix Bischofiae Javanicae 14 grams, Herba Pileae Cavaleriei 12 grams, smelly Wheeling 12 grams, add 8 times of water gagings, decocted 1.5 hours, and filtered; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, drying is pulverized, and namely gets the powder that meets 1 day consumption of normal adult.
Be used for the treatment of hepatic fibrosis.Oral, every bu is taken for twice sooner or later.
Specific embodiment 3
Take by weighing: Radix Phyllanthi cochinchinensis 12 gram, Caulis et Folium Pavettae Hongkongensis 14 grams, Radix Coicis 12 grams, Herba Violae diamantiacae 10 grams, Lan Huashi ginseng 9 grams, Herba Swertiae heteranthae 8 grams, smelly Radix Dichroae 8 grams, Caulis et Folium Cynanchi Auriculati 8 grams, Thamnolia vermicularis (Ach.) Asa-hina 14 grams, Herba Cirrohopetali Andersonii 12 grams, Herba tiarellae polyphyllae 10 grams, Herba Parnassiae Wightianae 14 grams, Rhizoma Panacis bipinnatifidi 12 grams, hang rock wind 10 grams, thorn pear 12 grams, Herbia Wedeliae 12 grams, Radix Bischofiae Javanicae 14 grams, Herba Pileae Cavaleriei 12 grams, smelly Wheeling 12 grams, add 8 times of water gagings, decocted 1.5 hours, and filtered; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, drying adds an amount of dextrin and correctives again, granulates according to this area common process, and packing can make the granule that meets 1 day consumption of normal adult.
Be used for the treatment of hepatic fibrosis.Oral, every bu is taken for twice sooner or later.
Claims (1)
1. Chinese medicine for the treatment of hepatic fibrosis, it is characterized in that, be prepared from by the medical material of following weight proportion: 12 parts of Radix Phyllanthi cochinchinensiss, 14 parts of Caulis et Folium Pavettae Hongkongensis, 12 parts of Radix Coicis, 10 parts of Herba Violae diamantiacaes, 9 parts of Lan Huashi ginsengs, 8 parts of Herba Swertiae heteranthaes, 8 parts of smelly Radix Dichroaes, 8 parts of Caulis et Folium Cynanchi Auriculati, 14 parts of Thamnolia vermicularis (Ach.) Asa-hina, 12 parts of Herba Cirrohopetali Andersoniis, 10 parts of Herba tiarellae polyphyllaes, 14 parts of Herba Parnassiae Wightianaes, 12 parts of Rhizoma Panacis bipinnatifidis, hang 10 parts of rock wind, 12 parts in pear of thorn, 12 parts of Herbia Wedeliaes, 14 parts of Radix Bischofiae Javanicae, 12 parts of Herba Pileae Cavalerieis, 12 parts of smelly Wheelings.
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| CN113244281A (en) * | 2021-06-09 | 2021-08-13 | 贵州医科大学 | Application of Huangshui Zhitong extract in preparing medicine for treating, protecting and regulating liver fibrosis diseases |
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| CN101176780A (en) * | 2006-11-10 | 2008-05-14 | 辽宁中医药大学附属医院 | Medicament for curing hepatic fibrosis and early cirrhosis |
| CN101632829A (en) * | 2009-09-03 | 2010-01-27 | 福建归真堂药业股份有限公司 | Anti-hepatofibrosis traditional Chinese medicament composition, preparation method thereof and medicament preparation |
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| CN103751462A (en) * | 2014-02-08 | 2014-04-30 | 刘方荣 | Traditional Chinese medicine tincture for treating wind-heat and blood dryness type steatorrhea dermatitis |
| CN113244281A (en) * | 2021-06-09 | 2021-08-13 | 贵州医科大学 | Application of Huangshui Zhitong extract in preparing medicine for treating, protecting and regulating liver fibrosis diseases |
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