CN103610928B - A kind of Chinese medicine for the treatment of anaphy lactoid purpura nephritis - Google Patents
A kind of Chinese medicine for the treatment of anaphy lactoid purpura nephritis Download PDFInfo
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Abstract
The present invention relates to a kind of Chinese medicine for the treatment of anaphy lactoid purpura nephritis, be prepared from by the medical material of following weight proportion: Radix Dendropanacis 10 parts, Radix Indigoferae Teysmannii 14 parts, Ocimum Basilicum 14 parts, great Ye south Soviet Union 12 parts, Herba speranskiae tuberculatae 10 parts, Antidesma ghaesembilla Gaerth. 12 parts, Herba Senecionis Oldhamiani 20 parts, sudden blue 14 parts, Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.) 16 parts, phalaenopsis 22 parts, Flos Artemisiae finitae 8 parts, tongue spray 15 parts, blue 14 parts of Spica piperis betlis, Radix Seu Flos Koelreuteriae Bipinnatae 10 parts, to raw polystichun 14 parts, Flos Musellae Lasiocarpae 16 parts, Radix premnae ligustroidis 12 parts, Herba sedi kamtschatici 10 parts, Rhizoma Pinelliae Preparatum 16 parts, Yunnan Herba Plantaginis 12 parts, Radix Zanthoxyli multijugi 16 parts, Radix Aristolochiae Tagalae 15 parts.Clinical trial certificate, the present invention can safe and effective treatment anaphy lactoid purpura nephritis.
Description
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine for the treatment of anaphy lactoid purpura nephritis.
Background technology
The basic lesion of anaphy lactoid purpura nephritis is the scorching immune disease of necrotizing small vessel, is characterized as skin purpura, gastroenteritis haemorrhagica and kidney damage.The usual sicken age of its sickness rate is larger, and renal damage incidence rate is higher, and nephropathy degree is also heavier.Henoch Schonlein purpura nephritis is the chronic nephropathy causing kidney generation pathology damage due to the blood capillary generation allergic inflammation of human body.Clinically, patient by there is skin purpura, arthralgia, suffer from abdominal pain, to have blood in stool and hematuria is the Symptoms of feature.Mild symptoms is very resuspended, except seeing skin, and gastrointestinal tract, outside the symptoms such as joint, early stage most patient visual hematuria and albuminuria, the rarely seen microscopic hematuria of the lighter.
The effective medicine of generally recognized as safe is still lacked at present for anaphy lactoid purpura nephritis.
Involved by Chinese medicine of the present invention, the present Research of medical material is as follows:
Root, stem or bark that Radix Dendropanacis [source] is joined for Araliaceae authority ginseng or change leaf tree.。Autumn, winter excavate root, really get stem branch or strip bark, clean, section, and using fresh herb or solarization are used.[function cures mainly] expelling wind and removing dampness; Promoting blood circulation and detumescence.Main air pain of dampness syndrome; Hemiplegia; Headache; Menoxenia; Traumatic injury; Skin ulcer swells.
The root that Radix Indigoferae Teysmannii [source] is leguminous plant Ti Shi Folium et Caulis Indigoferae Tinctoriae.Summer, autumn gather.[function cures mainly] softening the hard mass.Control mass in the abdomen.
Ocimum Basilicum [source] Labiatae Ocimum Basilicum OcimumgratissimumL.var.suave(Willd.) Hook.f., with all herbal medicine.[function cures mainly] relieving the exterior syndrome by diaphoresis, expelling wind and removing dampness, eliminating stasis to stop pain.For anemofrigid cold, headache, pipe abdomen fullness, dyspepsia, stomachache, enteritis, diarrhea, treating swelling and pain by traumatic injury, rheumatic arthritis; Venom is controlled in external, eczema, dermatitis.
The Herb that large Ye Nansu [source] is the large Ye Nansu of aroid.The whole year all can gather, and clean, cutting is dried or using fresh herb.[function cures mainly] eliminating stasis to stop pain; Relaxing muscles and tendons and activating QI and blood in the collateral; Nourishing the lung to arrest cough.Main angina pectoris; Treating swelling and pain by traumatic injury; Fracture; Rheumatalgia; Numb limbs and tense tendons; Bronchitis; Pertussis.
The herb of Herba speranskiae tuberculatae [source] Euphorbiaceae Speranskia plant speranskia tuberculata, Balsaminaceae herbaceous plant Flos Impatientis, Bignoniaceae Incarvillea AJuss plant Herba Incarvilleae sinensis, pulse family Vetch plant Herba Viciae Amoenae and the Herb of Ericaceae Gaultheria plant Caulis et folium gaultheriae yunnanensis.Xia Qiucai.[function cures mainly] expelling wind and removing dampness, removing toxic substances pain relieving.For rheumatic arthritis; Sore swollen toxin is controlled in external.
The leaf spring that Antidesma ghaesembilla Gaerth. [source] is euphorbia plant Antidesma ghaesembilla Gaerth., summer pluck, and clean, using fresh herb.[function cures mainly] draws out the pus antipruritic.Main children's's head sore.
The herb that Herba Senecionis Oldhamiani [source] is feverfew Pu root.Summer gathers, and cleans, using fresh herb or dry.[function cures mainly] heat-clearing and toxic substances removing; Dampness removing; Invigorate blood circulation.Main carbuncle pyogenic infections from tumour or sore; Urinary system infection; Eczema; Traumatic injury.
Sudden blue [source] is the herb of acanthaceous plant plan Herb Pararuelliae delavayanae.[function cures mainly] wind and heat dispersing; Resolving toxin and disinhibiting the throat.Main cold, fever; Laryngopharynx swelling and pain; Folding larynx.
Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.) [source] lichens Umbilicariaceae Umbilcaria plant red abdomen Umbillcaria esculenta GyrophorahypocrocinaJatta, is used as medicine with thallus.Gather in after summer rain or drizzle sky, removing foreign material, dry.[function cures mainly] invigorating the stomach and promoting digestion, regulating QI to relieve pain.For dyspepsia, infantile malnutrition, abdominal distention, stomachache, dysentery.
The herb that phalaenopsis [source] is orchid phalaenopsis.Summer, autumn gather, using fresh herb or dry.[function cures mainly] dispelling wind to relieve the exterior syndrome; Relaxing muscles and tendons and activating QI and blood in the collateral; Bone-setting pain stopping.Main cold, fever; Headache; Rheumatic arthralgia; Traumatic injury; Fracture.
Flos Artemisiae finitae [source] Compositae mugwort Flos Artemisiae finitae ArtemisiafinitaKitag., is used as medicine with alabastrum.Summer, the flowers are in blossom puts front collection, dries in the shade.[function cures mainly] anthelmintic.For ascariasis.
Tongue spray [source] Urticaceae Pilea plant tongue spray Pileajaponica(Maxim.) Hand.-Mazz., with all herbal medicine.Xia Qiucai, cleans and dries, or using fresh herb.[function cures mainly] heat-clearing and toxic substances removing, eliminating dampness by diuresis diuresis.For tonsillitis, urinary tract infection, cervicitis, leucorrhea with red and white discharge.
Spica piperis betlis orchid [source] Piperaceae Piper plant folium urticae Fructus Piperis PiperboehmeriaefoliumWall., is used as medicine with Herb.The whole year can adopt, and section is dried.[function cures mainly] expelling wind and cold, regulating QI to relieve pain.For flu, stomachache, dysmenorrhea, traumatic injury, rheumatic ostalgia.
Root, root bark or flower that Radix Seu Flos Koelreuteriae Bipinnatae [source] is sapindaceous plant Radix Seu Flos Koelreuteriae Bipinnatae.Summer, autumn gather.[function cures mainly] wind and heat dispersing, cough-relieving, parasite killing.
To raw polystichun [source] fern Dryopteridaceae to raw polystichun Polystichumdeltodon(Bak.) Diels, with all herbal medicine.[function cures mainly] promoting blood circulation and stopping pain, detumescence, diuresis, preventing cold; Traumatic injury is controlled in external, venom.
The flower that Flos Musellae Lasiocarpae [source] is Musaceae plant Flos Musellae Lasiocarpae.Summer, florescence in autumn gather, and dry or using fresh herb.[function cures mainly] leukorrhagia stopping; Hemostasis.Main leucorrhea; Metrorrhagia; Have blood in stool.
The root that Radix premnae ligustroidis [source] is Verbenaceae Herba Premnae Ligustroidis.Gather, clean, section is dried after autumn.[function cures mainly] heat clearing away; Dampness removing.Main dysentery; Hemorrhoid; Proctoptosis; Toothache; Edema.
The herb that Herba sedi kamtschatici [source] is crassulaceae plants Herba sedi kamtschatici or root.Summer, autumn gather, using fresh herb or dry.[function cures mainly] invigorates blood circulation, hemostasis, mind calming, dampness removing, detumescence, removing toxic substances.Control traumatic injury, hemoptysis, spit blood, have blood in stool, cardiopalmus, carbuncle
Rhizoma Pinelliae Preparatum [source] this product is the Preparation process product of the Rhizoma Pinelliae.[function cures mainly] drying dampness to eliminate phlegm.For abundant expectoration cough with asthma, phlegm retention vertigo and palpitation, dizziness due to wind-phlegm, syncope due to accumulation of phlegm is had a headache.
Yunnan Herba Plantaginis [source] Plantaginaceae Yunnan Herba Plantaginis PlantagoerosaWall., with seed, all herbal medicine.[function cures mainly] clearing away heat and promoting diuresis, eliminates the phlegm, removing heat from blood, removing toxic substances.For edema oliguria, the puckery pain of pyretic stranguria, heat-damp in summer dysentery, phlegm-heat cough, hematemesis and epistaxis, carbuncle sore tumefacting virus.
The root that Radix Zanthoxyli multijugi [source] is rutaceae Radix Zanthoxyli multijugi.The whole year can adopt.[function cures mainly] cold expelling, analgesia.
Radix Aristolochiae Tagalae [source] aristolochiaceae plant Radix Aristolochiae Tagalae AristolochiafordianaHemsl., is used as medicine with root.Xia Qiu gathers, and clean section is dried.[function cures mainly] wind-expelling pain-stopping, removing toxic substances and promoting subsidence of swelling.For stomachache, rheumatic ostalgia, traumatic injury, venom.
Summary of the invention
The present invention aims to provide a kind of Chinese medicine for the treatment of anaphy lactoid purpura nephritis, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective healing anaphy lactoid purpura nephritis.
In order to achieve the above object, the present invention is by the following technical solutions:
A kind of Chinese medicine for the treatment of anaphy lactoid purpura nephritis, it is characterized in that, be prepared from by the medical material of following weight proportion: Radix Dendropanacis 10 parts, Radix Indigoferae Teysmannii 14 parts, Ocimum Basilicum 14 parts, great Ye south Soviet Union 12 parts, Herba speranskiae tuberculatae 10 parts, Antidesma ghaesembilla Gaerth. 12 parts, Herba Senecionis Oldhamiani 20 parts, sudden blue 14 parts, Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.) 16 parts, phalaenopsis 22 parts, Flos Artemisiae finitae 8 parts, tongue spray 15 parts, blue 14 parts of Spica piperis betlis, Radix Seu Flos Koelreuteriae Bipinnatae 10 parts, to raw polystichun 14 parts, Flos Musellae Lasiocarpae 16 parts, Radix premnae ligustroidis 12 parts, Herba sedi kamtschatici 10 parts, Rhizoma Pinelliae Preparatum 16 parts, Yunnan Herba Plantaginis 12 parts, Radix Zanthoxyli multijugi 16 parts, Radix Aristolochiae Tagalae 15 parts.
Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:
1, physical data
Inventor collects the out-patient of 119 routine anaphy lactoid purpura nephritis-2012 years in February, 2011 altogether between December, age 37-63 year, course of disease 1-6.Be divided at random: treatment group 86 example, blank group 33 example.The two groups of data such as age, state of an illness there was no significant differences, have comparability.
2, test method
The capsule that the oral the present invention of 2.1 treatment group obtains according to specific embodiment 1, sooner or later respectively once.30 days courses for the treatment of.
2.2 blank group oral placebo capsules, sooner or later respectively once.30 days courses for the treatment of.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
Recovery from illness: clinical symptoms all disappears, lab testing is normal, observes having no recurrence in three months more afterwards.Take a turn for the better: clinical symptom relief, the state of an illness is controlled, lab testing improvement or normal.Invalid: clinical symptoms is without being clearly better or increasing the weight of.
3.2 treatment statistical results are in table 1.
Table 1 liang group comparitive study
| Group | n | Recovery from illness | Take a turn for the better | Invalid | Total effective rate (%) | Untoward reaction example |
| Treatment group | 86 | 20（23.2%） | 48（55.8%) | 18（20.9%) | 79% | 0 |
| Blank group | 33 | 0 | 6（18.2%） | 27（81.8%） | 18.2% | 0 |
Visible, the medicine that the present invention obtains can safe and effective treatment anaphy lactoid purpura nephritis.
Detailed description of the invention
In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
specific embodiment 1
Take: Radix Dendropanacis 10 grams, Radix Indigoferae Teysmannii 14 grams, Ocimum Basilicum 14 grams, great Ye south Soviet Union 12 grams, Herba speranskiae tuberculatae 10 grams, Antidesma ghaesembilla Gaerth. 12 grams, Herba Senecionis Oldhamiani 20 grams, sudden blue 14 grams, Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.) 16 grams, phalaenopsis 22 grams, Flos Artemisiae finitae 8 grams, tongue spray 15 grams, blue 14 grams of Spica piperis betlis, Radix Seu Flos Koelreuteriae Bipinnatae 10 grams, to raw polystichun 14 grams, Flos Musellae Lasiocarpae 16 grams, Radix premnae ligustroidis 12 grams, Herba sedi kamtschatici 10 grams, Rhizoma Pinelliae Preparatum 16 grams, Yunnan Herba Plantaginis 12 grams, Radix Zanthoxyli multijugi 16 grams, Radix Aristolochiae Tagalae 15 grams, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, incapsulate shell, the capsule of adult normal's 1 day consumption must be met.
Be used for the treatment of anaphy lactoid purpura nephritis.Oral, every bu is taken for twice sooner or later.
specific embodiment 2
Take: Radix Dendropanacis 10 grams, Radix Indigoferae Teysmannii 14 grams, Ocimum Basilicum 14 grams, great Ye south Soviet Union 12 grams, Herba speranskiae tuberculatae 10 grams, Antidesma ghaesembilla Gaerth. 12 grams, Herba Senecionis Oldhamiani 20 grams, sudden blue 14 grams, Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.) 16 grams, phalaenopsis 22 grams, Flos Artemisiae finitae 8 grams, tongue spray 15 grams, blue 14 grams of Spica piperis betlis, Radix Seu Flos Koelreuteriae Bipinnatae 10 grams, to raw polystichun 14 grams, Flos Musellae Lasiocarpae 16 grams, Radix premnae ligustroidis 12 grams, Herba sedi kamtschatici 10 grams, Rhizoma Pinelliae Preparatum 16 grams, Yunnan Herba Plantaginis 12 grams, Radix Zanthoxyli multijugi 16 grams, Radix Aristolochiae Tagalae 15 grams, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, pulverize, the powder of adult normal's 1 day consumption must be met.
Be used for the treatment of anaphy lactoid purpura nephritis.Oral, every bu is taken for twice sooner or later.
specific embodiment 3
Take: Radix Dendropanacis 10 grams, Radix Indigoferae Teysmannii 14 grams, Ocimum Basilicum 14 grams, great Ye south Soviet Union 12 grams, Herba speranskiae tuberculatae 10 grams, Antidesma ghaesembilla Gaerth. 12 grams, Herba Senecionis Oldhamiani 20 grams, sudden blue 14 grams, Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.) 16 grams, phalaenopsis 22 grams, Flos Artemisiae finitae 8 grams, tongue spray 15 grams, blue 14 grams of Spica piperis betlis, Radix Seu Flos Koelreuteriae Bipinnatae 10 grams, to raw polystichun 14 grams, Flos Musellae Lasiocarpae 16 grams, Radix premnae ligustroidis 12 grams, Herba sedi kamtschatici 10 grams, Rhizoma Pinelliae Preparatum 16 grams, Yunnan Herba Plantaginis 12 grams, Radix Zanthoxyli multijugi 16 grams, Radix Aristolochiae Tagalae 15 grams, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, then add appropriate dextrin and correctives, granulate according to this area common process, packaging, can obtain the granule meeting adult normal's 1 day consumption.
Be used for the treatment of anaphy lactoid purpura nephritis.Oral, every bu is taken for twice sooner or later.
Claims (1)
1. treat the Chinese medicine of anaphy lactoid purpura nephritis for one kind, it is characterized in that, be prepared from by the medical material of following weight proportion: Radix Dendropanacis 10 parts, Radix Indigoferae Teysmannii 14 parts, Ocimum Basilicum 14 parts, great Ye south Soviet Union 12 parts, Herba speranskiae tuberculatae 10 parts, Antidesma ghaesembilla Gaerth. 12 parts, Herba Senecionis Oldhamiani 20 parts, sudden blue 14 parts, Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.) 16 parts, phalaenopsis 22 parts, Flos Artemisiae finitae 8 parts, tongue spray 15 parts, blue 14 parts of Spica piperis betlis, Radix Seu Flos Koelreuteriae Bipinnatae 10 parts, to raw polystichun 14 parts, Flos Musellae Lasiocarpae 16 parts, Radix premnae ligustroidis 12 parts, Herba sedi kamtschatici 10 parts, Rhizoma Pinelliae Preparatum 16 parts, Yunnan Herba Plantaginis 12 parts, Radix Zanthoxyli multijugi 16 parts, Radix Aristolochiae Tagalae 15 parts.
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1279961A (en) * | 2000-06-29 | 2001-01-17 | 耿铁 | Kidneg recovery pill |
| CN1682982A (en) * | 2005-02-22 | 2005-10-19 | 黄资源 | A Chinese medicinal pill for treating chronic nephropathy and renal insufficiency |
| CN102836393A (en) * | 2012-10-15 | 2012-12-26 | 赵如风 | Medicament for treating chronic nephritis through permeation and kidney-activating cell regeneration therapy |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1279961A (en) * | 2000-06-29 | 2001-01-17 | 耿铁 | Kidneg recovery pill |
| CN1682982A (en) * | 2005-02-22 | 2005-10-19 | 黄资源 | A Chinese medicinal pill for treating chronic nephropathy and renal insufficiency |
| CN102836393A (en) * | 2012-10-15 | 2012-12-26 | 赵如风 | Medicament for treating chronic nephritis through permeation and kidney-activating cell regeneration therapy |
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