CN103656223B - A kind of Chinese medicine for the treatment of hepatic fibrosis - Google Patents
A kind of Chinese medicine for the treatment of hepatic fibrosis Download PDFInfo
- Publication number
- CN103656223B CN103656223B CN201310748927.9A CN201310748927A CN103656223B CN 103656223 B CN103656223 B CN 103656223B CN 201310748927 A CN201310748927 A CN 201310748927A CN 103656223 B CN103656223 B CN 103656223B
- Authority
- CN
- China
- Prior art keywords
- parts
- radix
- grams
- hepatic fibrosis
- herba
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 206010019668 Hepatic fibrosis Diseases 0.000 title claims abstract description 20
- 239000003814 drug Substances 0.000 title claims abstract description 15
- 235000013399 edible fruits Nutrition 0.000 claims abstract description 12
- 241000219495 Betulaceae Species 0.000 claims abstract description 9
- 241000759836 Cornus chinensis Species 0.000 claims abstract description 8
- 241000934856 Daphne Species 0.000 claims abstract description 8
- 240000002853 Nelumbo nucifera Species 0.000 claims abstract description 8
- 241001659736 Vicia unijuga Species 0.000 claims abstract description 8
- 241000522649 Zornia Species 0.000 claims abstract description 8
- 235000006508 Nelumbo nucifera Nutrition 0.000 claims abstract description 7
- 235000006510 Nelumbo pentapetala Nutrition 0.000 claims abstract description 7
- 230000007306 turnover Effects 0.000 claims abstract description 7
- 235000017166 Bambusa arundinacea Nutrition 0.000 claims abstract description 6
- 235000017491 Bambusa tulda Nutrition 0.000 claims abstract description 6
- 244000082204 Phyllostachys viridis Species 0.000 claims abstract description 6
- 235000015334 Phyllostachys viridis Nutrition 0.000 claims abstract description 6
- 239000011425 bamboo Substances 0.000 claims abstract description 6
- 239000012567 medical material Substances 0.000 claims abstract description 6
- 230000006870 function Effects 0.000 description 20
- 208000002193 Pain Diseases 0.000 description 8
- 208000014674 injury Diseases 0.000 description 8
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 8
- 206010011224 Cough Diseases 0.000 description 7
- 239000008280 blood Substances 0.000 description 7
- 210000004369 blood Anatomy 0.000 description 7
- 231100000614 poison Toxicity 0.000 description 7
- 239000003440 toxic substance Substances 0.000 description 7
- 230000008736 traumatic injury Effects 0.000 description 7
- 206010000087 Abdominal pain upper Diseases 0.000 description 6
- 206010012735 Diarrhoea Diseases 0.000 description 5
- 206010017553 Furuncle Diseases 0.000 description 5
- 201000010099 disease Diseases 0.000 description 5
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 5
- 210000004185 liver Anatomy 0.000 description 5
- 230000001737 promoting effect Effects 0.000 description 5
- 208000008035 Back Pain Diseases 0.000 description 4
- 208000008930 Low Back Pain Diseases 0.000 description 4
- 230000001684 chronic effect Effects 0.000 description 4
- 208000001848 dysentery Diseases 0.000 description 4
- 241000196324 Embryophyta Species 0.000 description 3
- 206010062717 Increased upper airway secretion Diseases 0.000 description 3
- 206010030113 Oedema Diseases 0.000 description 3
- 208000004880 Polyuria Diseases 0.000 description 3
- 230000017531 blood circulation Effects 0.000 description 3
- 239000002775 capsule Substances 0.000 description 3
- 230000007812 deficiency Effects 0.000 description 3
- 230000035619 diuresis Effects 0.000 description 3
- 208000002173 dizziness Diseases 0.000 description 3
- 239000000706 filtrate Substances 0.000 description 3
- 238000001914 filtration Methods 0.000 description 3
- 210000003734 kidney Anatomy 0.000 description 3
- 208000026435 phlegm Diseases 0.000 description 3
- 230000001105 regulatory effect Effects 0.000 description 3
- 210000000952 spleen Anatomy 0.000 description 3
- 230000008961 swelling Effects 0.000 description 3
- 208000024891 symptom Diseases 0.000 description 3
- 210000002435 tendon Anatomy 0.000 description 3
- 230000001225 therapeutic effect Effects 0.000 description 3
- 241001586439 Aconitum sinomontanum Species 0.000 description 2
- 201000000736 Amenorrhea Diseases 0.000 description 2
- 206010001928 Amenorrhoea Diseases 0.000 description 2
- 241000159155 Cipadessa baccifera Species 0.000 description 2
- 206010010774 Constipation Diseases 0.000 description 2
- 208000008454 Hyperhidrosis Diseases 0.000 description 2
- 241000219050 Polygonaceae Species 0.000 description 2
- 208000009205 Tinnitus Diseases 0.000 description 2
- 206010053476 Traumatic haemorrhage Diseases 0.000 description 2
- 231100000540 amenorrhea Toxicity 0.000 description 2
- 230000004087 circulation Effects 0.000 description 2
- 208000019425 cirrhosis of liver Diseases 0.000 description 2
- 238000001035 drying Methods 0.000 description 2
- 201000006549 dyspepsia Diseases 0.000 description 2
- 235000013305 food Nutrition 0.000 description 2
- 239000008187 granular material Substances 0.000 description 2
- 230000023597 hemostasis Effects 0.000 description 2
- 241000411851 herbal medicine Species 0.000 description 2
- 208000019423 liver disease Diseases 0.000 description 2
- 201000004792 malaria Diseases 0.000 description 2
- 210000003205 muscle Anatomy 0.000 description 2
- 239000000047 product Substances 0.000 description 2
- 238000011084 recovery Methods 0.000 description 2
- 230000002040 relaxant effect Effects 0.000 description 2
- 230000004206 stomach function Effects 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 231100000886 tinnitus Toxicity 0.000 description 2
- 231100000331 toxic Toxicity 0.000 description 2
- 230000002588 toxic effect Effects 0.000 description 2
- 239000002435 venom Substances 0.000 description 2
- 210000001048 venom Anatomy 0.000 description 2
- 231100000611 venom Toxicity 0.000 description 2
- 206010002383 Angina Pectoris Diseases 0.000 description 1
- 241000208340 Araliaceae Species 0.000 description 1
- 206010003445 Ascites Diseases 0.000 description 1
- 206010007247 Carbuncle Diseases 0.000 description 1
- 235000008495 Chrysanthemum leucanthemum Nutrition 0.000 description 1
- 244000192528 Chrysanthemum parthenium Species 0.000 description 1
- 235000000604 Chrysanthemum parthenium Nutrition 0.000 description 1
- 241000142975 Cornaceae Species 0.000 description 1
- 206010011878 Deafness Diseases 0.000 description 1
- 201000004624 Dermatitis Diseases 0.000 description 1
- 229920001353 Dextrin Polymers 0.000 description 1
- 239000004375 Dextrin Substances 0.000 description 1
- 241001148765 Dryopteridaceae Species 0.000 description 1
- 208000005171 Dysmenorrhea Diseases 0.000 description 1
- 206010013935 Dysmenorrhoea Diseases 0.000 description 1
- 241001632410 Eleutherococcus senticosus Species 0.000 description 1
- 241000160765 Erebia ligea Species 0.000 description 1
- 206010019233 Headaches Diseases 0.000 description 1
- 208000032843 Hemorrhage Diseases 0.000 description 1
- 206010019799 Hepatitis viral Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 241001226158 Lastreopsis Species 0.000 description 1
- 241000612162 Maesa Species 0.000 description 1
- 241000738807 Maesa japonica Species 0.000 description 1
- 208000019255 Menstrual disease Diseases 0.000 description 1
- 206010050031 Muscle strain Diseases 0.000 description 1
- 241000209477 Nymphaeaceae Species 0.000 description 1
- 241000233855 Orchidaceae Species 0.000 description 1
- 240000005373 Panax quinquefolius Species 0.000 description 1
- 235000003140 Panax quinquefolius Nutrition 0.000 description 1
- 241001527087 Panax vietnamensis Species 0.000 description 1
- 235000017726 Panax vietnamensis Nutrition 0.000 description 1
- 201000005702 Pertussis Diseases 0.000 description 1
- 241001529246 Platymiscium Species 0.000 description 1
- 206010035664 Pneumonia Diseases 0.000 description 1
- 244000292697 Polygonum aviculare Species 0.000 description 1
- 235000006386 Polygonum aviculare Nutrition 0.000 description 1
- 241001226483 Polystichum deltodon Species 0.000 description 1
- 206010036790 Productive cough Diseases 0.000 description 1
- 241000675470 Pronephrium penangianum Species 0.000 description 1
- 208000003251 Pruritus Diseases 0.000 description 1
- 206010040943 Skin Ulcer Diseases 0.000 description 1
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 description 1
- 240000002915 Solanum macrocarpon Species 0.000 description 1
- 241001148746 Thelypteridaceae Species 0.000 description 1
- 206010053615 Thermal burn Diseases 0.000 description 1
- 206010047601 Vitamin B1 deficiency Diseases 0.000 description 1
- 206010051373 Wound haemorrhage Diseases 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 201000009361 ascariasis Diseases 0.000 description 1
- 208000006673 asthma Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 208000002894 beriberi Diseases 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- 230000023555 blood coagulation Effects 0.000 description 1
- 238000009835 boiling Methods 0.000 description 1
- 206010006451 bronchitis Diseases 0.000 description 1
- 208000013116 chronic cough Diseases 0.000 description 1
- 208000019902 chronic diarrheal disease Diseases 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 210000002808 connective tissue Anatomy 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 231100000895 deafness Toxicity 0.000 description 1
- 206010061428 decreased appetite Diseases 0.000 description 1
- 230000006735 deficit Effects 0.000 description 1
- 235000019425 dextrin Nutrition 0.000 description 1
- 206010013990 dysuria Diseases 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 210000003414 extremity Anatomy 0.000 description 1
- 230000001605 fetal effect Effects 0.000 description 1
- 235000008384 feverfew Nutrition 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 235000021022 fresh fruits Nutrition 0.000 description 1
- 235000021472 generally recognized as safe Nutrition 0.000 description 1
- 231100000869 headache Toxicity 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 208000016354 hearing loss disease Diseases 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 230000037315 hyperhidrosis Effects 0.000 description 1
- 238000007654 immersion Methods 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 206010022437 insomnia Diseases 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 210000003127 knee Anatomy 0.000 description 1
- 210000000629 knee joint Anatomy 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 201000007227 lymph node tuberculosis Diseases 0.000 description 1
- 208000004396 mastitis Diseases 0.000 description 1
- 210000004914 menses Anatomy 0.000 description 1
- 230000002175 menstrual effect Effects 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 230000027939 micturition Effects 0.000 description 1
- 230000017074 necrotic cell death Effects 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- 230000007170 pathology Effects 0.000 description 1
- 239000000902 placebo Substances 0.000 description 1
- 229940068196 placebo Drugs 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 201000003068 rheumatic fever Diseases 0.000 description 1
- 201000005404 rubella Diseases 0.000 description 1
- 238000007665 sagging Methods 0.000 description 1
- 231100000019 skin ulcer Toxicity 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 230000002269 spontaneous effect Effects 0.000 description 1
- 208000024794 sputum Diseases 0.000 description 1
- 210000003802 sputum Anatomy 0.000 description 1
- 230000035900 sweating Effects 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 208000004371 toothache Diseases 0.000 description 1
- 230000008733 trauma Effects 0.000 description 1
- 201000001862 viral hepatitis Diseases 0.000 description 1
- 239000011800 void material Substances 0.000 description 1
- 210000002268 wool Anatomy 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The present invention relates to a kind of Chinese medicine for the treatment of hepatic fibrosis, be prepared from by the medical material of following weight proportion: northeast alder 14 parts, great Ye south Soviet Union 12 parts, Bai Ye do not turn over 10 parts, Herba Polygoni polystachyi 12 parts, Herba Polystichi Braunii 14 parts, raw polystichun 15 parts, Radix Daphnes altaicae 12 parts, the lotus base of a fruit 10 parts, flat bamboo joined 12 parts, Radix Solani Torvi 12 parts, Cornus chinensis 8 parts, Changuienia amoena Chien 10 parts, Abacopteris penangiana (Hook.) Ching 14 parts, Radix Maesae Japonicae 12 parts, Radix aconiti sinomontani 10 parts, Radix Zornia Diphyllae 14 parts, Vicia unijuga 12 parts, Herba Polygoni Runcinati 14 parts, Radix seu folium cipakessae cinerascentis 10 parts, Radix Et Caulis Acanthopanacis Senticosi 12 parts.Clinical trial certificate, the present invention can safe and effective treatment hepatic fibrosis.
Description
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine for the treatment of hepatic fibrosis.
Background technology
Hepatic fibrosis refers to the over-deposit of hepatic fibrosis connective tissue, is the unbalanced result of fibroplasia and fiber hydrolization.Fibroplasia is body for the one reparation reaction of damage, and caused by the various cause of disease repeatedly or the Chronic Liver parenchyma inflammation continued, necrosis can cause the continual fibroplasia of liver and form hepatic fibrosis.Develop from the clinical pathology of many chronic hepatopathys, particularly chronic viral hepatitis, hepatic fibrosis be chronic hepatopathy develop into liver cirrhosis must through stage.Now think that hepatic fibrosis still has to reverse to normal possibility, liver cirrhosis is then no.
The effective medicine of generally recognized as safe is still lacked at present for hepatic fibrosis.
Involved by Chinese medicine of the present invention, the present Research of medical material is as follows:
The fruit that northeast alder [source] is Betulaceae northeast alder or bark.Spring, summer, autumn all can adopt bark.Adopt lower infructescence after autumn, win fruit, dry.[function cures mainly] heat-clearing and toxic substances removing; Restrain astringent or styptic treatment for spontaneous sweating.Main diarrhoea; Traumatic hemorrhage.
The Herb that large Ye Nansu [source] is the large Ye Nansu of aroid.The whole year all can gather, and clean, cutting is dried or using fresh herb.[function cures mainly] eliminating stasis to stop pain; Relaxing muscles and tendons and activating QI and blood in the collateral; Nourishing the lung to arrest cough.Main angina pectoris; Treating swelling and pain by traumatic injury; Fracture; Rheumatalgia; Numb limbs and tense tendons; Bronchitis; Pertussis.
Bai Ye does not turn over [source] for feverfew hook bud Herba Leibnitziae root.Autumn, winter excavate, and clean, dry.[function cures mainly] removing heat-phlegm; Removing food stagnancy kills early.Main flu; Cough and asthma; Dysentery; Stomachache; Dyspepsia; Ascariasis; Traumatic hemorrhage.
The herb that Herba Polygoni polystachyi [source] is polygonaceae plant Herba Polygoni polystachyi.Gather for 6 ~ October herb, binding is dried.[function cures mainly] heat-clearing and toxic substances removing; Expelling wind and removing dampness.Main dysentery; Have loose bowels; Infantile dyspepsia; Rheumatism swells and ache; Traumatic injury.
The herb that Herba Polystichi Braunii [source] is shield-fern kind of plant Herba Polystichi Braunii.8 ~ JIUYUE is excavated, cutting, dries.[function cures mainly] heat-clearing and toxic substances removing.To cure the disease malicious dermexanthesis.
To raw polystichun [source] fern Dryopteridaceae to raw polystichun Polystichum deltodon (Bak.) Diels, with all herbal medicine.[function cures mainly] promoting blood circulation and stopping pain, detumescence, diuresis, preventing cold; Traumatic injury is controlled in external, venom.
Radix Daphnes altaicae [source] medical material Ji Yuan: be root and the Herb of thymelaeceae Radix Daphnes altaicae.[function cures mainly] expelling wind and cold; Expelling phlegm for arresting cough; Promoting the circulation of QI to relieve pain.Main anemofrigid cold; Cough with copious phlegm; Energy-stagnation stomachache.
The lotus base of a fruit [source] this product is the blade that the nearly stalk place of Folium Nelumbinis central authorities of nymphaeaceae plant lotus Nelumbo nucifera Gaertn. cuts.[function cures mainly] stomach function regulating is antiabortive, hemostasis leukorrhagia stopping.Can be used for the disease such as frequent fetal movement and bleeding not during menses.There is the merit of elevate a turnable ladder, can be used for again the diseases such as the sagging chronic diarrhea proctoptosis of clearing heat in QI system.
The herb that flat bamboo ginseng [source] is liliaceous plant crutch Rhizoma Bergeniae purpurascentis.Summer, autumn gather, and clean, dry.[function cures mainly] invigorating spleen to remove dampness stomach function regulating; Promoting blood circulation and detumescence.Main wet Sheng is insufficiency of the spleen; Diarrhoea; Edema; Dysuria; Food stagnation is had a stomachache; Dizziness and tinnitus; Menoxenia; Traumatic injury; Rubella; Infantile pneumonia.
Radix Solani Torvi [source] Solanaceae nightshade Radix Solani Torvi, is used as medicine with root.The whole year can adopt, and cleans and dries.[function cures mainly] dissipating blood stasis, stimulates the menstrual flow, detumescence, pain relieving, cough-relieving.Root: for traumatic injury stasis of blood pain, lumbar muscle strain, stomachache, toothache, amenorrhea, chronic cough.Fresh leaf: mash external application and can control innominate toxic swelling.
The fruit that Cornus chinensis [source] is Cornaceae plant Cornus chinensis.Fruit in autumn is plucked by ripe fruit in batches, is put in boiling water by fresh fruit and boils 10-15min, pull immersion cold water in time out, extrude seed while hot, get sarcocarp and dry or dry.[function cures mainly] the liver and the kidney tonifying; Convergence is solid de-.Main caused by liver and kidney deficiency; Have a dizzy spell; Deafness and tinnitus; Soreness of the waist and knees; Seminal emission; Frequent micturition; The empty hyperhidrosis of body.
The pseudobulb that Changuienia amoena Chien [source] is orchid Herba Changnieniae amoenae and herb.Summer, autumn gather, and clean, dry or using fresh herb.[function cures mainly] heat clearing away; Removing heat from blood; Removing toxic substances.Main cough; Sputum mixed with blood; Furuncle furuncle.
The rhizome that Abacopteris penangiana (Hook.) Ching [source] is Thelypteridaceae plant Pronephrium penangianum and herb.Autumn gathers.[function cures mainly] dissipating blood stasis blood, dehumidifying.Control lumbago due to trauma, the blood clotting stagnation of QI.
Radix Maesae Japonicae [source] Myrsinacea Maesa plant Radix Maesae Japonicae Maesa japonica (Thunb.) Moritzi, is used as medicine with root, leaf.The whole year can adopt, and cleans and dries.[function cures mainly] dispels the wind diuresis, hemostasis, detumescence.Root: headache, lumbago, edema, ascites; Leaf: wound hemorrhage is controlled in external.
Radix aconiti sinomontani [source] Ranunculaceae aconitum plant Aconitum sinomontanum Nakai Aconitum sinomontanum Nakai, is used as medicine with root.Xia Qiu gathers, and dries.[function cures mainly] expelling wind and removing dampness, eliminating stasis to stop pain.For lumbago, skelalgia of rheumatism, peratodynia, traumatic injury.
The root of Radix Zornia Diphyllae [source] leguminous plant Herba Zornia Diphyllae.[function cures mainly] heat clearing away, removing toxic substances.Control carbuncle, treat skin ulcer, beriberi edema, scrofula.
Vicia unijuga [source] pulse family Vetch plant Vicia unijuga Vicia unijuga A.Brown, with all herbal medicine.Xia Qiu gathers, and dries.[function cures mainly] tonify deficiency adjusts liver, regulating QI to relieve pain, clearing away heat and promoting diuresis.For dizziness, body is impractical swollen, stomachache; Furuncle furuncle is controlled in external.
The herb that Herba Polygoni Runcinati [source] is polygonaceae plant Herba Polygoni Runcinati and scarce waist leaf knotweed.Summer, autumn gather, and binding is dried or using fresh herb.[function cures mainly] heat-clearing and toxic substances removing; Relaxing muscles and tendons to promote blood circulation.Main dysentery; Have loose bowels; Leucorrhea with red and white discharge; Amenorrhea; Dysmenorrhea; Acute mastitis; Furuncle; Innominate toxic swelling; Venom; Traumatic injury; Impairment caused by overstrain lumbago.
Radix seu folium cipakessae cinerascentis [source] Meliaceae Cipadessa baecifera Miq platymiscium gray wool Cipadessa baecifera Miq., be used as medicine with root, leaf.Root can be adopted the whole year, and section is dried.Ye Xiaqiucai, using fresh herb or dry in the shade.[function cures mainly] heat-clearing and toxic substances removing, circulation of qi promoting relieving constipation, preventing the attack (or recurrence) of malaria.For flu, heating is not moved back, malaria, constipation, stomachache, dysentery, rheumatic arthritis; Children's's dermatitis is controlled in external, skin pruritus, burn and scald.
Radix Et Caulis Acanthopanacis Senticosi [source] this product is the drying of Araliaceae Radix Et Caulis Acanthopanacis Senticosi Acanthopanax senticosus (Rupr. et Maxim.) Harms, root and rhizome or stem.Spring, Qiu Erji gather, cleaning, drying.[function cures mainly] replenishing QI to invigorate the spleen, tonifying the kidney for tranquilization.For deficiency of spleen-YANG and kidneyYANG, body void is weak, inappetence, soreness of waist and knee joint, insomnia and dreamful sleep.
Summary of the invention
The present invention aims to provide a kind of Chinese medicine for the treatment of hepatic fibrosis, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective healing hepatic fibrosis.
In order to achieve the above object, the present invention is by the following technical solutions:
A kind of Chinese medicine for the treatment of hepatic fibrosis, it is characterized in that, be prepared from by the medical material of following weight proportion: northeast alder 14 parts, great Ye south Soviet Union 12 parts, Bai Ye do not turn over 10 parts, Herba Polygoni polystachyi 12 parts, Herba Polystichi Braunii 14 parts, raw polystichun 15 parts, Radix Daphnes altaicae 12 parts, the lotus base of a fruit 10 parts, flat bamboo joined 12 parts, Radix Solani Torvi 12 parts, Cornus chinensis 8 parts, Changuienia amoena Chien 10 parts, Abacopteris penangiana (Hook.) Ching 14 parts, Radix Maesae Japonicae 12 parts, Radix aconiti sinomontani 10 parts, Radix Zornia Diphyllae 14 parts, Vicia unijuga 12 parts, Herba Polygoni Runcinati 14 parts, Radix seu folium cipakessae cinerascentis 10 parts, Radix Et Caulis Acanthopanacis Senticosi 12 parts.
Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:
1, physical data
Inventor's in JIUYUE, 2011 collects the out-patient of 142 routine hepatic fibrosis altogether between in March ,-2013, age 23-57 year, course of disease 0.5-5.Be divided at random: treatment group 107 example, blank group 35 example.The two groups of data such as age, state of an illness there was no significant differences, have comparability.
2, test method
The capsule that the oral the present invention of 2.1 treatment group obtains according to specific embodiment 1, sooner or later respectively once.30 days courses for the treatment of.
2.2 blank group oral placebo capsules, sooner or later respectively once.30 days courses for the treatment of.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
Recovery from illness: clinical symptoms all disappears, test chamber inspection is normal, observes having no recurrence in three months more afterwards.Take a turn for the better: clinical symptom relief, the state of an illness is controlled, lab testing improvement or normal.Invalid: clinical symptoms is without being clearly better or increasing the weight of.
3.2 treatment statistical results are in table 1.
Table 1 liang group comparitive study
| Group | n | Recovery from illness | Take a turn for the better | Invalid | Total effective rate (%) | Untoward reaction example |
| Treatment group | 107 | 27（25.2%） | 72（67.3%) | 8（7.5%) | 92.5% | 0 |
| Blank group | 35 | 0 | 4（11.4%） | 31（88.6%） | 11.4% | 0 |
Visible, the medicine that the present invention obtains can safe and effective treatment hepatic fibrosis.
Detailed description of the invention
In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
specific embodiment 1
Take: northeast alder 14 grams, great Ye south Soviet Union 12 grams, Bai Ye do not turn over 10 grams, Herba Polygoni polystachyi 12 grams, Herba Polystichi Braunii 14 grams, raw polystichun 15 grams, Radix Daphnes altaicae 12 grams, the lotus base of a fruit 10 grams, flat bamboo joined 12 grams, Radix Solani Torvi 12 grams, Cornus chinensis 8 grams, Changuienia amoena Chien 10 grams, Abacopteris penangiana (Hook.) Ching 14 grams, Radix Maesae Japonicae 12 grams, Radix aconiti sinomontani 10 grams, Radix Zornia Diphyllae 14 grams, Vicia unijuga 12 grams, Herba Polygoni Runcinati 14 grams, Radix seu folium cipakessae cinerascentis 10 grams, Radix Et Caulis Acanthopanacis Senticosi 12 grams, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, incapsulate shell, the capsule of adult normal's 1 day consumption must be met.
Be used for the treatment of hepatic fibrosis.Oral, every bu is taken for twice sooner or later.
specific embodiment 2
Take: northeast alder 14 grams, great Ye south Soviet Union 12 grams, Bai Ye do not turn over 10 grams, Herba Polygoni polystachyi 12 grams, Herba Polystichi Braunii 14 grams, raw polystichun 15 grams, Radix Daphnes altaicae 12 grams, the lotus base of a fruit 10 grams, flat bamboo joined 12 grams, Radix Solani Torvi 12 grams, Cornus chinensis 8 grams, Changuienia amoena Chien 10 grams, Abacopteris penangiana (Hook.) Ching 14 grams, Radix Maesae Japonicae 12 grams, Radix aconiti sinomontani 10 grams, Radix Zornia Diphyllae 14 grams, Vicia unijuga 12 grams, Herba Polygoni Runcinati 14 grams, Radix seu folium cipakessae cinerascentis 10 grams, Radix Et Caulis Acanthopanacis Senticosi 12 grams, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, pulverize, the powder of adult normal's 1 day consumption must be met.
Be used for the treatment of hepatic fibrosis.Oral, every bu is taken for twice sooner or later.
specific embodiment 3
Take: northeast alder 14 grams, great Ye south Soviet Union 12 grams, Bai Ye do not turn over 10 grams, Herba Polygoni polystachyi 12 grams, Herba Polystichi Braunii 14 grams, raw polystichun 15 grams, Radix Daphnes altaicae 12 grams, the lotus base of a fruit 10 grams, flat bamboo joined 12 grams, Radix Solani Torvi 12 grams, Cornus chinensis 8 grams, Changuienia amoena Chien 10 grams, Abacopteris penangiana (Hook.) Ching 14 grams, Radix Maesae Japonicae 12 grams, Radix aconiti sinomontani 10 grams, Radix Zornia Diphyllae 14 grams, Vicia unijuga 12 grams, Herba Polygoni Runcinati 14 grams, Radix seu folium cipakessae cinerascentis 10 grams, Radix Et Caulis Acanthopanacis Senticosi 12 grams, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, then add appropriate dextrin and correctives, granulate according to this area common process, packaging, can obtain the granule meeting adult normal's 1 day consumption.
Be used for the treatment of hepatic fibrosis.Oral, every bu is taken for twice sooner or later.
Claims (1)
1. treat the Chinese medicine of hepatic fibrosis for one kind, it is characterized in that, be prepared from by the medical material of following weight proportion: northeast alder 14 parts, great Ye south Soviet Union 12 parts, Bai Ye do not turn over 10 parts, Herba Polygoni polystachyi 12 parts, Herba Polystichi Braunii 14 parts, raw polystichun 15 parts, Radix Daphnes altaicae 12 parts, the lotus base of a fruit 10 parts, flat bamboo joined 12 parts, Radix Solani Torvi 12 parts, Cornus chinensis 8 parts, Changuienia amoena Chien 10 parts, Abacopteris penangiana (Hook.) Ching 14 parts, Radix Maesae Japonicae 12 parts, Radix aconiti sinomontani 10 parts, Radix Zornia Diphyllae 14 parts, Vicia unijuga 12 parts, Herba Polygoni Runcinati 14 parts, Radix seu folium cipakessae cinerascentis 10 parts, Radix Et Caulis Acanthopanacis Senticosi 12 parts.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310748927.9A CN103656223B (en) | 2013-12-31 | 2013-12-31 | A kind of Chinese medicine for the treatment of hepatic fibrosis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310748927.9A CN103656223B (en) | 2013-12-31 | 2013-12-31 | A kind of Chinese medicine for the treatment of hepatic fibrosis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103656223A CN103656223A (en) | 2014-03-26 |
| CN103656223B true CN103656223B (en) | 2015-09-02 |
Family
ID=50295781
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310748927.9A Active CN103656223B (en) | 2013-12-31 | 2013-12-31 | A kind of Chinese medicine for the treatment of hepatic fibrosis |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103656223B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104857306A (en) * | 2015-05-31 | 2015-08-26 | 白薇 | Drug for curing liver fibrosis |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101015668A (en) * | 2007-01-16 | 2007-08-15 | 李卓伦 | Fatty liver treating medicine |
| CN101040894B (en) * | 2007-04-16 | 2010-05-19 | 黄仁彬 | Preparing and application of Yulangsan extract |
-
2013
- 2013-12-31 CN CN201310748927.9A patent/CN103656223B/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CN103656223A (en) | 2014-03-26 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103800650B (en) | A kind of Chinese medicine for the treatment of removing heat from the lung and dissipating phlegm | |
| CN103341009B (en) | Traditional Chinese medicine for treating posthepatitic cirrhosis | |
| CN103656223B (en) | A kind of Chinese medicine for the treatment of hepatic fibrosis | |
| CN103316252B (en) | A kind of Chinese medicine for the treatment of hepatic fibrosis | |
| CN103610931B (en) | A kind of Chinese medicine for the treatment of tuberculous pleuritis | |
| CN103800759B (en) | One treats person in middle and old age's rheumatism, rheumatoid Chinese medicine | |
| CN103610822A (en) | Traditional Chinese medicine for treating nodular panniculitis | |
| CN103623227B (en) | A kind of Chinese medicine for the treatment of boil of the nose | |
| CN103610989B (en) | A kind of Chinese medicine for the treatment of acute pyogenic cholangitis | |
| CN103690715A (en) | Traditional Chinese medicine for treating ischemic colitis | |
| CN103610928B (en) | A kind of Chinese medicine for the treatment of anaphy lactoid purpura nephritis | |
| CN103599335B (en) | Traditional Chinese medicine for treatment of chronic colitis | |
| CN103520325B (en) | Traditional Chinese medicine for treating alcohol type fatty liver | |
| CN103623273B (en) | A kind of Chinese medicine for the treatment of Henoch Schonlein purpura nephritis | |
| CN103520397B (en) | Traditional Chinese medicine for treating pityriasis rubra pilaris | |
| CN103623187B (en) | A kind of Chinese medicine for the treatment of angle closure glaucoma | |
| CN103784749B (en) | A kind of Chinese medicine for the treatment of juvenile rheumatoid arthritis | |
| CN103860778A (en) | Traditional Chinese medicament for treating middle and old aged rheumatism arthralgia syndrome | |
| CN103705819B (en) | A kind of Chinese medicine treating intestinal Behcet disease | |
| CN103623332B (en) | Traditional Chinese medicine for treating perinephritis | |
| CN103550659B (en) | Traditional Chinese medicine for treating abdominal migraine syndrome | |
| CN103520460B (en) | Traditional Chinese medicine for treating chronic bronchitis | |
| CN103599378B (en) | Traditional Chinese medicine for treating sciatica | |
| CN103610979B (en) | A kind of Chinese medicine for the treatment of colitis | |
| CN103690858B (en) | A kind of Chinese medicine treating benign biliary stricture |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20191120 Address after: 215422 laozha West Street, Jinlang Town, Fuqiao Town, Taicang City, Suzhou City, Jiangsu Province Patentee after: Taicang Qiujing Plastic Mould Co., Ltd. Address before: 264000 Yu Huang Ding hospital, 20 Yu Dong Road, Zhifu District, Shandong, Yantai Patentee before: Zhang Fengrong |
|
| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20201012 Address after: Room 308, No.6 office building, No.1, Lugong Road, Port Development Zone, Fuqiao Town, Taicang City, Jiangsu Province, 215400 Patentee after: Suzhou Zhilue Intellectual Property Operation Co., Ltd Address before: 215422 laozha West Street, Jinlang Town, Fuqiao Town, Taicang City, Suzhou City, Jiangsu Province Patentee before: TAICANG QIUJING PLASTIC MOULD Co.,Ltd. |