CN103599328B - Traditional Chinese medicine for treatment of pulmonary alveolar proteinosis - Google Patents
Traditional Chinese medicine for treatment of pulmonary alveolar proteinosis Download PDFInfo
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Abstract
The invention relates to a traditional Chinese medicine for treatment of pulmonary alveolar proteinosis. The traditional Chinese medicine is made from the following medicinal materials by weight: 15 parts of spirea, 12 parts of Porana racemosa, 12 parts of Sedum lineare, 10 parts of Anemone dichotoma roots, 10 parts of gambier, 12 parts of Cayratia japonica, 14 parts of Pyrethrum tatsienense, 18 parts of suberect spatholobus stems, 8 parts of Rhizoma Dioscoreae Hypoglaucae, 22 parts of Clerodendrum yunnanense flowers, 20 parts of stems and leaves of Viburnum taitoense Hayata, 16 parts of Dicranum majus, 15 parts of Cissus assamica (Laws.) Craib, 10 parts of straightstalk alpine meadowrue roots, 14 parts of Panax pseudo-ginseng var. bipinnatifidus, 16 parts of Calystegia hederacea, and 12 parts of Coprinus sterqulinus Fr. Clinical experiments prove that the traditional Chinese medicine provided by the invention is safe and effective for treatment of pulmonary alveolar proteinosis.
Description
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine for the treatment of pulmonary alveolar proteinosis.
Background technology
Pulmonary alveolar proteinosis (PAP) is the not bright Uncommon Diseases of a kind of reason.Be characterized in there is the rich phospholipoprotein deposition of insolubility in alveolar, clinical symptoms main manifestations is for breathing hard, coughing and expectoration.Chest x-ray is in two lung diffusivity pulmonary infiltrates shade.Pathological examination is to be filled with the protein-like substance of periodic acid snow husband (PAS) stained positive for feature in alveolar.The clinical manifestation of primary disease is widely different, and what have without any clinical symptoms, only can find when health check-up; The patient about having 1/5 then with Secondary cases pulmonary infection symptom for First presentation, have cough, heating, chest uncomfortable; Separately have an appointment 1/2 patient hiddenly attack onset, show as cough, dyspnea, weak, minority case can have low grade fever and spitting of blood, and respiratory symptom and the pulmonary lesion scope of getting involved have certain relation.
The effective medicine of generally recognized as safe is still lacked at present for pulmonary alveolar proteinosis.
Involved by Chinese medicine of the present invention, the present Research of medical material is as follows:
Ramulus et Folium Spiraeae Salicifolia [source] Rosaceae Spiraea light leaf Ramulus et Folium Spiraeae Salicifolia, is used as medicine with root and tender leaf.The whole year adopts root, cleans and dries; Tender leaf is adopted summer.[function cures mainly] heat-clearing and toxic substances removing.For conjunctival congestion and swelling pain, headache, toothache, cough due to lung-heat; Wound hemorrhage is controlled in external.
Moth rattan [source] Convolvulaceae moth rattan Porana racemosa Roxb., with all herbal medicine.[function cures mainly] delivers, it is long-pending to help digestion.Cure mainly Common Cold, food stagnation does not disappear.
The stem and leaf that Herba Sedi Linearis [source] is crassulaceae plants Herba Sedi Linearis.Using fresh herb is with adopting; Or the summer, Qiu Liangji, extract Herb, clean, decontrol in water and scald, pick up, to dry or a heatable brick bed is done.[function cures mainly] heat-clearing and toxic substances removing; Dampness removing; Hemostasis.Main laryngopharynx swelling and pain; Conjunctival congestion toxic swelling; Pyretic toxicity carbuncle; Furuncle; Erysipelas; Herpes zoster; Burn and scald; Venom; Jaundice; Damp-heat dysentery; Have blood in stool; Metrorrhagia; Traumatic hemorrhage; Verruca plana.
The rhizome that two discrimination Anemone cathayensis Kitag. roots [source] are ranunculaceae plant two discrimination Anemone cathayensis Kitag..Autumn excavates, and dries.[function cures mainly] relaxing muscles and tendons to promote blood circulation; Heat-clearing and toxic substances removing.Main traumatic injury; Rheumatic arthritis; Dysentery; Carbuncle sore.
GAMBIER [source] decocts the dry extract that juice concentrates for Maguireothamnus speciosus Uncaria gambier Roxb. band leaf twig.For Maguireothamnus speciosus Uncaria gambier Roxb. band leaf twig decocts the dry extract that juice concentrates.
The rhizome that Abacopteris penangiana (Hook.) Ching [source] is Thelypteridaceae plant Pronephrium penangianum and herb.Autumn gathers.[function cures mainly] dissipating blood stasis blood, dehumidifying.Control lumbago due to trauma, the blood clotting stagnation of QI.
The head inflorescence that Flos Pyrethri tatsienensis [source] is feverfew Flos Pyrethri tatsienensis.8 ~ JIUYUE is picked flowers, and dries in the shade.[function cures mainly] invigorates blood circulation, damp eliminating, antiinflammatory, pain relieving.Control traumatic injury, damp-heat syndrome.
The rattan that Kadsura interior [source] is Schisandraceae Plant Kadsura interior or Kadsura heteroclita.Autumn gathers, and cleans and dries use, or endures cream use.[function cures mainly] hemopoietic and blood; Regulating menstruation seed.Main deficient qi and blood; The paralysis of limb fiber crops; Rheumatic arthralgia; Deficient sterile; Seminal emission nebulousurine; Menoxenia; Leucorrhea with red and white discharge.
Rhizoma Dioscoreae Hypoglaucae [source] this product is the dry rhizome of Dioscoreaceae Plant Powder back of the body Rhizoma Dioscoreae Dioscorea hypoglauca Palibin.Autumn, season in winter two excavate, and removing fibrous root, cleans, and section, dries.[function cures mainly] dampness removing goes turbid, wind expelling stagnation removing.For stranguria marked by chyluria, nebulousurine, leukorrhagia, rheumatic arthralgia, articular instability, lumbocrural pain.
The flower that Radix clerodendri yunnanensis flower [source] is Verbenaceae Radix clerodendri yunnanensis.The 4-7 month gathers when blooming, and dries.[function cures mainly] stops blooding; Leukorrhagia stopping.Main metrorrhagia; Leukorrhagia.
To the stem and leaf of leaf oil Folium Cannabis [source] for Radix Ophiopogonis plant platform Dong Caulis Viburni Dilatati.Spring, summer gather, using fresh herb.[function cures mainly] eliminating stasis to stop pain; Relieving constipation.Main traumatic injury; Constipation.
The plant that bent tail moss [source] of many capsules is the bent tail moss of the many capsules of Dicranaceae plant.Summer, autumn gather, and clean, dry.[function cures mainly] clearing away lung-heat to relieve cough.Main cough due to lung-heat.
Fan blade rattan [source] Vitaceae fan blade rattan Cissus assamica (Laws.) Craib, is used as medicine with root.[function cures mainly] draws out the pus detumescence, eliminating stasis to stop pain.Cure mainly traumatic injury, sprain, Fengshi Guanjie pain, fracture, carbuncle pyogenic infections from tumour or sore.Formula is with still controlling osteomyelitis.Also nourishing agent can be made.
The root that Radix Thalictri elati [source] is ranunculaceae plant compound leaf Herba Veratri Taliensis.Autumn, winter gather, and clean and dry.[function cures mainly] heat clearing and damp drying, removing pathogenic heat from blood and toxic substance from the body.Control dysphoria with smothery sensation thirsty, vomiting uncomfortable in chest, hematemesis and epistaxis, damp-heat dysentery, conjunctival congestion aphtha, carbuncle furunculosis, jaundice caused by damp-heat.
Rhizoma Panacis bipinnatifidi [source] is araliaceae ginseng plant's Rhizoma Panacis bipinnatifidi Panax bipinnatifidus Seem., is used as medicine with root stock.Autumn end excavates, clean dry for subsequent use.[function cures mainly] strengthening by means of tonics, eliminating stasis to stop pain, hemostasis.For weak after being ill, hemoptysis of pulmonary tuberculosis, epistaxis, amenorrhea, puerperal abdominal pain due to blood stasis, arthralgia due to cold-dampnes, traumatic injury.
DAWANHUA [source] is Convolvulaceae calystegia plant DAWANHUA Calystegin hederacea Wall., is used as medicine with root stock and flower.Autumn digs root stock, cleans and dries or using fresh herb.Xia Qiu picks flowers using fresh herb.[function cures mainly] invigorating the spleen and benefiting QI, diuresis, regulating menstruation, leukorrhagia stopping; For insufficiency of the spleen dyspepsia, menoxenia, leucorrhea, milk is rare.Pain relieving; Toothache is controlled in external.
Excrement ghost umbrella [source] Mycophyta Basidiomycetes Agaricales Agaricaceae excrement ghost umbrella Coprinus sterquilinus Fr., is used as medicine with sporophore.[function cures mainly] beneficial the intestines and stomach, phlegm-eliminiating and qi-regulating, removing toxic substances, detumescence.Often eating can be aid digestion, eliminates the phlegm, and controls innominate toxic swelling and other carbuncle sore.
Summary of the invention
The present invention aims to provide a kind of Chinese medicine for the treatment of pulmonary alveolar proteinosis, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective healing pulmonary alveolar proteinosis.
In order to achieve the above object, the present invention is by the following technical solutions:
A kind of Chinese medicine for the treatment of pulmonary alveolar proteinosis, it is characterized in that, be prepared from by the medical material of following weight proportion: Ramulus et Folium Spiraeae Salicifolia 15 parts, 12 parts, moth rattan, Herba Sedi Linearis 12 parts, two discrimination Anemone cathayensis Kitag. roots 10 parts, GAMBIER 10 parts, Abacopteris penangiana (Hook.) Ching 12 parts, Flos Pyrethri tatsienensis 14 parts, Kadsura interior 18 parts, Rhizoma Dioscoreae Hypoglaucae 8 parts, Radix clerodendri yunnanensis spend 22 parts, to leaf oil Folium Cannabis 20 parts, the bent tail moss 16 parts of many capsules, 15 parts, fan blade rattan, Radix Thalictri elati 10 parts, Rhizoma Panacis bipinnatifidi 14 parts, DAWANHUA 16 parts, excrement ghost 12 parts, umbrella.
Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:
1, physical data
Inventor's in JIUYUE, 2010 collects the out-patient of 98 routine pulmonary alveolar proteinosises altogether between in November ,-2012, age 31-58 year, course of disease 1-4.Be divided at random: treatment group 91 example, blank group 27 example.The two groups of data such as age, state of an illness there was no significant differences, have comparability.
2, test method
The capsule that the oral the present invention of 2.1 treatment group obtains according to specific embodiment 1, sooner or later respectively once.30 days courses for the treatment of.
2.2 blank group oral placebo capsules, sooner or later respectively once.30 days courses for the treatment of.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
Recovery from illness: clinical symptoms all disappears, test chamber inspection is normal, observes having no recurrence in three months more afterwards.Take a turn for the better: clinical symptom relief, the state of an illness is controlled, lab testing improvement or normal.Invalid: clinical symptoms is without being clearly better or increasing the weight of.
3.2 treatment statistical results are in table 1.
Table 1 liang group comparitive study
| Group | n | Recovery from illness | Take a turn for the better | Invalid | Total effective rate (%) | Untoward reaction example |
| Treatment group | 91 | 31（34.1%） | 37（40.6%) | 23（25.3%) | 74.7% | 0 |
| Blank group | 27 | 1(3.7%) | 3（11.1%） | 23（85.2%） | 14.8% | 0 |
Visible, the medicine that the present invention obtains can safe and effective treatment pulmonary alveolar proteinosis.
Detailed description of the invention
In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
specific embodiment 1
Take: Ramulus et Folium Spiraeae Salicifolia 15 grams, 12 grams, moth rattan, Herba Sedi Linearis 12 grams, two discrimination Anemone cathayensis Kitag. roots 10 grams, GAMBIER 10 grams, Abacopteris penangiana (Hook.) Ching 12 grams, Flos Pyrethri tatsienensis 14 grams, Kadsura interior 18 grams, Rhizoma Dioscoreae Hypoglaucae 8 grams, Radix clerodendri yunnanensis spend 22 grams, to leaf oil Folium Cannabis 20 grams, the bent tail moss 16 grams of many capsules, 15 grams, fan blade rattan, Radix Thalictri elati 10 grams, Rhizoma Panacis bipinnatifidi 14 grams, DAWANHUA 16 grams, excrement ghost 12 grams, umbrella, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, incapsulate shell, the capsule of adult normal's 1 day consumption must be met.
Be used for the treatment of pulmonary alveolar proteinosis.Oral, every bu is taken for twice sooner or later.
specific embodiment 2
Take: Ramulus et Folium Spiraeae Salicifolia 15 grams, 12 grams, moth rattan, Herba Sedi Linearis 12 grams, two discrimination Anemone cathayensis Kitag. roots 10 grams, GAMBIER 10 grams, Abacopteris penangiana (Hook.) Ching 12 grams, Flos Pyrethri tatsienensis 14 grams, Kadsura interior 18 grams, Rhizoma Dioscoreae Hypoglaucae 8 grams, Radix clerodendri yunnanensis spend 22 grams, to leaf oil Folium Cannabis 20 grams, the bent tail moss 16 grams of many capsules, 15 grams, fan blade rattan, Radix Thalictri elati 10 grams, Rhizoma Panacis bipinnatifidi 14 grams, DAWANHUA 16 grams, excrement ghost 12 grams, umbrella, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, pulverize, the powder of adult normal's 1 day consumption must be met.
Be used for the treatment of pulmonary alveolar proteinosis.Oral, every bu is taken for twice sooner or later.
specific embodiment 3
Take: Ramulus et Folium Spiraeae Salicifolia 15 grams, 12 grams, moth rattan, Herba Sedi Linearis 12 grams, two discrimination Anemone cathayensis Kitag. roots 10 grams, GAMBIER 10 grams, Abacopteris penangiana (Hook.) Ching 12 grams, Flos Pyrethri tatsienensis 14 grams, Kadsura interior 18 grams, Rhizoma Dioscoreae Hypoglaucae 8 grams, Radix clerodendri yunnanensis spend 22 grams, to leaf oil Folium Cannabis 20 grams, the bent tail moss 16 grams of many capsules, 15 grams, fan blade rattan, Radix Thalictri elati 10 grams, Rhizoma Panacis bipinnatifidi 14 grams, DAWANHUA 16 grams, excrement ghost 12 grams, umbrella, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, then add appropriate dextrin and correctives, granulate according to this area common process, packaging, can obtain the granule meeting adult normal's 1 day consumption.
Be used for the treatment of pulmonary alveolar proteinosis.Oral, every bu is taken for twice sooner or later.
Claims (1)
1. treat the Chinese medicine of pulmonary alveolar proteinosis for one kind, it is characterized in that, be prepared from by the medical material of following weight proportion: Ramulus et Folium Spiraeae Salicifolia 15 parts, 12 parts, moth rattan, Herba Sedi Linearis 12 parts, two discrimination Anemone cathayensis Kitag. roots 10 parts, GAMBIER 10 parts, Abacopteris penangiana (Hook.) Ching 12 parts, Flos Pyrethri tatsienensis 14 parts, Kadsura interior 18 parts, Rhizoma Dioscoreae Hypoglaucae 8 parts, Radix clerodendri yunnanensis spend 22 parts, to leaf oil Folium Cannabis 20 parts, the bent tail moss 16 parts of many capsules, 15 parts, fan blade rattan, Radix Thalictri elati 10 parts, Rhizoma Panacis bipinnatifidi 14 parts, DAWANHUA 16 parts, excrement ghost 12 parts, umbrella.
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| CN201310649387.9A CN103599328B (en) | 2013-12-06 | 2013-12-06 | Traditional Chinese medicine for treatment of pulmonary alveolar proteinosis |
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| CN201310649387.9A CN103599328B (en) | 2013-12-06 | 2013-12-06 | Traditional Chinese medicine for treatment of pulmonary alveolar proteinosis |
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| CN1736435A (en) * | 2005-09-12 | 2006-02-22 | 陈沙 | Chinese medicinal preparation for treating rhinitis and preparation process thereof |
| CN103301210A (en) * | 2013-06-24 | 2013-09-18 | 周国生 | Traditional Chinese medicine for treating varicosity |
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