CN105943963A - Medicine for treating pig pneumonia - Google Patents

Medicine for treating pig pneumonia Download PDF

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CN105943963A
CN105943963A CN201610462583.9A CN201610462583A CN105943963A CN 105943963 A CN105943963 A CN 105943963A CN 201610462583 A CN201610462583 A CN 201610462583A CN 105943963 A CN105943963 A CN 105943963A
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parts
radix
medicine
herba
brown
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蒙焕文
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A61K36/8998Hordeum (barley)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/287Chrysanthemum, e.g. daisy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/34Campanulaceae (Bellflower family)
    • A61K36/346Platycodon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/42Cucurbitaceae (Cucumber family)
    • A61K36/428Trichosanthes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/483Gleditsia (locust)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539Scutellaria (skullcap)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/65Paeoniaceae (Peony family), e.g. Chinese peony
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/68Plantaginaceae (Plantain Family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/734Crataegus (hawthorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/86Violaceae (Violet family)

Abstract

The invention discloses a medicine for treating pig pneumonia. The medicine is prepared from the following components in parts by weight: 16-38 parts of rhizoma decumbentis, 16-38 parts of spina gleditsiae, 16-38 parts of wild chrysanthemum flowers, 16-38 parts of viola, 16-38 parts of scutellaria baicalensis, 16-38 parts of platycodon grandiflorum, 16-38 parts of charred fructus crataegi, 16-38 parts of brown malts, 16-38 parts of prepared liquorice roots, 28-55 parts of radix angelicae dahuricae, 28-55 parts of akebia stems, 28-55 parts of tetrapanax papyriferus, 28-55 parts of radix paeoniae rubra, 28-55 parts of fructus trichosanthis, 28-55 parts of abrus herb, 28-55 parts of longhairy antenoron herb and 28-55 parts of plantain herb. The medicine can promote blood of pig lungs to flow and dredge bronchus, so that previous elasticity of alveolus pulmonis is recovered and the pig pneumonia can be effectively and rapidly treated; and the medicine is safe and has no toxic or side effect and no residues.

Description

A kind of medicine treating hyopneumoniae
Technical field
The present invention relates to livestock medicine field, be specifically related to a kind of medicine treating hyopneumoniae.
Background technology
Hyopneumoniae is the common frdquently encountered disease of pig, and the cause of disease mainly has: 1, pig house humidity is unclean, and swinery is crowded without winter protection equipment, Resistance declines;2, lack of skill during perfusion, causes medicine to enter lung tissue induction foreign body pneumonia through trachea;3, some passes Catch an illness, parasitic disease cause pneumonia.
Hyopneumoniae cardinal symptom has: heating, lack of appetite, and cough, diminished breath sound, nasal cavity stream mucus, expired gas has corrupt gas Taste etc..Hyopneumoniae badly influences the growth of pig, there will be death time serious, brings serious economic damage to pig-breeding family Lose.
The Western medicine such as current antibiotic remain the main method for the treatment of hyopneumoniae, such as penicillin, aminophenazone, sulfadiazine Although the Western medicine such as sodium have good therapeutic effect to hyopneumoniae, but Western medicine is difficult to excrete, and produces drug residue, and body can be made to produce Raw Drug resistance, the normal growth affecting pig is grown.Along with people's growing interest to food safety, western medicine hyopneumoniae faces Huge pressure.
Summary of the invention
For above deficiency, the present invention provides a kind of instant effect, low cost, the treatment that has no drug resistance, have no side effect The medicine of hyopneumoniae.
For solving the problems referred to above, the present invention is achieved through the following technical solutions:
A kind of medicine treating hyopneumoniae, is made up of the component of following weight portion: Radix et Rhizoma Thalictri 16~38 parts, Spina Gleditsiae 16~ 38 parts, Flos Chrysanthemi Indici 16~38 parts, Herba Violae 16~38 parts, Radix Scutellariae 16~38 parts, Radix Platycodonis 16~38 parts, Fructus Crataegi (parched to brown) 16~38 parts, Jiao Fructus Hordei Germinatus 16~38 parts, Radix Glycyrrhizae Preparata 16~38 parts, the Radix Angelicae Dahuricae 28~55 parts, Caulis Akebiae 28~55 parts, Medulla Tetrapanacis 28~55 parts, Radix Paeoniae Rubra 28~55 Part, Fructus Trichosanthis 28~55 parts, Herba Abri 28~55 parts, Herba Lysimachiae 28~55 parts, Herba Plantaginis 28~55 parts.
Preferably, the component of the following weight portion of medicine of described treatment hyopneumoniae is made: Radix et Rhizoma Thalictri 20~35 parts, Spina Gleditsiae 20~35 parts, Flos Chrysanthemi Indici 20~35 parts, Herba Violae 20~35 parts, Radix Scutellariae 20~35 parts, Radix Platycodonis 20~35 parts, Fructus Crataegi (parched to brown) 20~35 Part, Fructus Hordei Germinatus (parched to brown) 20~35 parts, Radix Glycyrrhizae Preparata 20~35 parts, the Radix Angelicae Dahuricae 40~50 parts, Caulis Akebiae 40~50 parts, Medulla Tetrapanacis 40~50 parts, Radix Paeoniae Rubra 40~50 parts, Fructus Trichosanthis 40~50 parts, Herba Abri 40~50 parts, Herba Lysimachiae 40~50 parts, Herba Plantaginis 40~50 parts.
It is further preferred that the medicine of above-mentioned treatment hyopneumoniae is made up of the component of following weight portion: Radix et Rhizoma Thalictri 30 parts, soap Fructus Gleditsia acupuncture 30 parts, Flos Chrysanthemi Indici 30 parts, Herba Violae 30 parts, Radix Scutellariae 30 parts, Radix Platycodonis 30 parts, Fructus Crataegi (parched to brown) 30 parts, Fructus Hordei Germinatus (parched to brown) 30 parts, Radix Glycyrrhizae Preparata 30 Part, the Radix Angelicae Dahuricae 45 parts, Caulis Akebiae 45 parts, Medulla Tetrapanacis 45 parts, Radix Paeoniae Rubra 45 parts, Fructus Trichosanthis 45 parts, Herba Abri 45 parts, Herba Lysimachiae 45 parts, Herba Plantaginis 45 parts.
In such scheme, described Spina Gleditsiae is Fructus Gleditsia obtained by 45%~75% ethanol solution impregnation process for using concentration Thorn.
In such scheme, the pharmaceutical dosage form of described treatment hyopneumoniae can be in powder, granule, pill, tablet, decoction Any one.
Each tcm components pharmacology that the present invention uses is specific as follows:
Radix et Rhizoma Thalictri, for Ranunculaceae thalictrum spp leafy Thalictrum aquilegifolium L. var. sibiricum Regel Thalictrum foliolosum DC. and plateau Thalictrum aquilegifolium L. var. sibiricum Regel T.cultratum Wall.T.deciternatum Boiv, is used as medicine with root.Effect: 1. " detailed outline lifts something lost ": " peeling In film outer and the pathogenic heat of grain, children's's cold and pox section use." 2. " Chinese herbal medicine is commonly used in Tibet ": " heat-clearing and toxic substances removing, dispel the wind removing heat from blood, disappears Scorching dysentery relieving.Control conjunctivitis, infectious hepatitis, carbuncle furuncle, dysentery.Leaf, flower curing arthritis." 3. " Chinese Herbal Medicine in Xinjiang handbook): " heat clearing and damp drying." cure mainly: heat clearing and damp drying, removing toxic substances.Control dysentery, enteritis, infectious hepatitis, flu, measles, carbuncle furuncle, conjunctiva Scorching.
Spina Gleditsiae, for the dry Spina jujubae of leguminous plant Fructus Gleditsia Gleditsia sinensis Lam..There is detumescence poison holding, Evacuation of pus, effect of parasite killing.Be usually used in carbuncle from the beginning of or difficulty in discharging of pus;External treatment scabies leprosy.
Flos Chrysanthemi Indici (formal name used at school: Dendranthema indicum) is Compositae herbaceos perennial, Flos Chrysanthemi Indici cold nature, tool Dispelling wind and heat pathogens, subduing swelling and detoxicating.The diseases such as furuncle carbuncle, laryngopharynx swelling and pain, wind-fire acute conjunctivitis, headache dizziness can be treated.
Herba Violae, (formal name used at school: Corydalis bungeana Turcz.), another name: Herba corydalis edulis (Plants of Beijing will, Inner Mongol plant Will), Peng Shi Herba corydalis edulis (Plants of Beijing will), Bu Shi Herba Violae (northeast medicinal plants figure will) etc..For perennial herb, with dry herb Hyoscine, has effect of heat-clearing and toxic substances removing, cures mainly the diseases such as carbuncle, furuncle, anemopyretic cold, bronchitis, hepatitis, enteritis.
Radix Scutellariae (Classification system: Scutellaria baicalensis Georgi), calls Radix Scutellariae, tsuchikane tea root, is Labiatae Scutellaria herbaceos perennial.The root of Radix Scutellariae is used as medicine, bitter in the mouth, cold in nature, has heat clearing and damp drying, eliminating fire and detoxication, stops blooding, pacifies The effects such as tire.Cure mainly epidemic febrile disease, upper respiratory tract infection, cough due to lung-heat, damp and hot jaundice, pneumonia, dysentery, hemoptysis, conjunctival congestion, fetal movement not The diseases such as peace, hypertension, carbuncle furuncle.The clinical antibiotic property of Radix Scutellariae is better than Rhizoma Coptidis, and does not develops immunity to drugs.
Radix Platycodonis (Platycodon grandiflorus), another name burden flower, Radix Platycodonis, mitral flower, be that perennial herb is planted Thing, its root can be used as medicine, and has the effects such as eliminating phlegm and stopping cough, lung qi dispersing, evacuation of pus.
Fructus Crataegi (parched to brown), effect: promoting digestion and invigorating the stomach, circulation of qi promoting dissipating blood stasis.For meat stagnation, gastral cavilty distension, dysentery stomachache, blood stasis warp Close, postpartum stagnation, trusted subordinate's twinge, hernia pain;Hyperlipemia.
Fructus Hordei Germinatus (parched to brown), effect: 1, digestion-aid effect: this product contains α and beta amylase.And that starch is amylose with amylopectin is mixed Compound.The glucose molecule of composition amylose is connected with α-Isosorbide-5-Nitrae glycoside key, and arranges in straight chain.Amylopectin is short directly by several Chain polyglucose cross arrangement.Branched amylopectin molecules also has in addition to α-Isosorbide-5-Nitrae glycoside key α-1,6 glycoside keys.α and beta amylase can water Solving α-Isosorbide-5-Nitrae glycoside key, to α-1,6 glycoside keys are without effect.Amylose complete hydrolysis can be become maltose, alpha amylase to be then allowed to by beta amylase Resolving into short straight key polyglucose (i.e. dextrin), the latter can be hydrolyzed into maltose for beta amylase again.Therefore starch forms sediment at α and β Maltose and dextrin it is decomposed under the effect of powder enzyme.Gastric acid and pepsic secretion are seemingly had and slightly promote to make by Fructus Hordei Germinatus decoct With.2, hypoglycemic activity: Fructus Hordei Germinatus preserved material is oral can make rabbit reduce with normal person's blood glucose.Grain water extract-alcohol precipitation highly finished product are made 5% injection inject 200mg to rabbit, can make blood glucose reduce by 40% or more, the most just recover.3, antifungal Effect: hordenine A and B contained by this product has antifungal activity.4, suppression prolactin antagonist is released into: Fructus Hordei Germinatus decoct 100-200g/d mouth Clothes, when Healthy People sleep or paspertin metoclopramide can be made to test, prolactin antagonist release peak is suppressed, and this may take Fructus Hordei Germinatus with women Soup delactation functions is relevant, to simple galactorrhea patient, galactorrhea can be made to disappear or alleviate, but paspertin metoclopramide test reaction peak is the most suppressed System, to the amenorrhea having Prolactinoma in Pituitary organic disease--galactorrhea syndromes is invalid.5, other effect: the Fructus Hordei Vulgaris contained by this product Its pharmacological action of alkali is similar to ephedrine.1.0mg/kg dosage can strengthen anxiety and the motion in Cavia porcellus uterus, and with the increase of dosage And increase.The cat bronchospasm causing neostigmine, can be allowed to expand, and effective dose is 0.5-1.0mg/kg, but aligns Often the effect of cat is the least.Also have radioactive protective action.
Radix Glycyrrhizae Preparata, Radix Glycyrrhizae Preparata is the Radix Glycyrrhizae baked with honey, modern study, and Radix Glycyrrhizae Preparata contains glycyrrhizin, enoxolone, sweet The multiple chemical composition such as grass polysaccharide, has antiinflammatory and anti-allergy action, scalable body's immunity, antitumor and pain relieving Effect.Therefore the primary efficacy of Radix Glycyrrhizae Preparata is and middle emergency, lung moistening, removing toxic substances, coordinating the actions of various ingredients in a prescription.Being usually used in weakness of the spleen and stomach, asthenia is weary Power, severe palpitation, irregularly intermittent and regularly intermittent pulse, Radix Aconiti Lateralis Preparata poison can be solved.
The Radix Angelicae Dahuricae, is used as medicine with root, the function such as the dehumidifying that gets rid of illness, evacuation of pus granulation promoting, promoting blood circulation and stopping pain.Cure mainly anemofrigid cold, headache, nose Scorching, toothache.The diseases such as leucorrhea with red and white discharge, bitterly furuncle and phyma poison, also can make spice.
Caulis Akebiae, cures mainly: for stranguria, edema, vexed dark coloured urine, aphtha of the mouth and tongue, amenorrhea breast is few, damp and hot arthralgia pain.
Medulla Tetrapanacis (Tetrapanax papyriferus), another name bandit is de-, from business, flowers and plants etc. southern, alive, partial, for Araliaceae The stem pith of plant rice-paper plant.Supplement to the Herbal: rice-paper plant, raw versant.Leaf like Bi fiber crops, have in the heart flesh, the most lovely, woman worker take with Jewelry." elegant " cloud takes off also from southern, alive.One cloud medicinal herbs, the raw south of the River, main parasitosis, modern custom also name Medulla Tetrapanacis.Medulla Tetrapanacis is promoting diuresis to clear away damp pathogen Chinese medicine, cures mainly: the puckery pain of hygropyrexia dark coloured urine, gonorrhea, edema oliguria, agalactia.
Radix Paeoniae Rubra, for ranunculaceae plant Radix Paeoniae Rubra or the dry root of river Radix Paeoniae Rubra.Spring, season in autumn two excavate, and remove rhizome, fibrous root and mud Sand, dries.Hardship, is slightly cold.Return Liver Channel.There is clearing away heat and cooling blood, effect of blood circulation promoting and blood stasis dispelling.
Fructus Trichosanthis, have another name called melon building, medicine melon, pharmacological action: antibacterial, antitumaous effect.Fructus Trichosanthis is in vitro to escherichia coli, Song Nei Shi Dysentery bacterium, Bacillus proteus etc. have some inhibitory action.Some dermatophytes is also had in various degree by infusion (1:2) in vitro Inhibitory action.In vitro in test, whole Fructus Trichosanthis decoct (20% decoct) has lethal effect to ascites cells.
Herba Abri, for the dry Herb of leguminous plant abrus cantoniensis Hance.Hardship sweet, micro-, cool.There is a dampness removing jaundice eliminating, heat-clearing and toxic substances removing, Effect of dispersing the depressed liver-QI for alleviating pain.Being usually used in damp and hot yellow cellulitis, side of body rib does not relaxes, and epigastric distending pain, acute mastitis swells and ache.
Herba Lysimachiae, for Ofthe Primulaceae, another name: Lysimachia christinae Hance, Drymoglossum subcordatum, Cui Pingcao, lotus bud grass, Boiled small dumplings with pork grass, Jin Suo Spoon, Herba Glechomae, to seat grass, leaf Herba Lysimachiae, Qian Yecao, Qian Qianjin etc..Herb hyoscine, has clearing away heat and promoting diuresis, wind-expelling pain-stopping, hemostasis Granulation promoting, eliminating inflammation and expelling toxin, the merit of parasite killing.Can treating acute and chronic hepatitis, icterohepatitis, cholecystitis, nephritis, urinary system infection, almond Adenitis, stomatitis and carbuncle furuncle treat poison, venom, acute mastitis, dysentery, malaria, pneumorrhagia etc..
Herba Plantaginis, sweet in the mouth, cold in nature.There is diuresis, heat clearing away, improving eyesight, effect of eliminating the phlegm.Cure mainly urinary obstruction, stranguria with turbid discharge, band Under, hematuria, jaundice, edema, hematodiarrhoea, have loose bowels, epistaxis, conjunctival congestion and swelling pain, sore throat, cough, skin ulcer etc..
The mutually coordinated effect of the present invention each herbal component by using, makes the medicine prepared can promote Pulmonis Sus domestica portion blood Liquid stream moves, and dredges bronchus, helps to improve the active substance of alveolar surface, makes alveolar recover original elasticity, can be fast and effectively Treatment hyopneumoniae, and there is safe without toxic side effect, the advantage of noresidue.
Detailed description of the invention
Further illustrate the present invention below in conjunction with specific embodiment, but the present invention is not limited only to these embodiments following.
Embodiment 1
A kind of medicine treating hyopneumoniae, is made up of the component of following weight portion: Radix et Rhizoma Thalictri 16 parts, Spina Gleditsiae 38 parts, open country Flos Chrysanthemi 16 parts, Herba Violae 38 parts, Radix Scutellariae 16 parts, Radix Platycodonis 38 parts, Fructus Crataegi (parched to brown) 16 parts, Fructus Hordei Germinatus (parched to brown) 38 parts, Radix Glycyrrhizae Preparata 16 parts, the Radix Angelicae Dahuricae 55 Part, Caulis Akebiae 28 parts, Medulla Tetrapanacis 55 parts, Radix Paeoniae Rubra 28 parts, Fructus Trichosanthis 55 parts, Herba Abri 28 parts, Herba Lysimachiae 55 parts, Herba Plantaginis 28 parts.Wherein, Described Spina Gleditsiae is Spina Gleditsiae obtained by 45% ethanol solution impregnation process for using concentration.Described impregnation process is specifically, soak Take out after steeping 3 days and dry.
Process for preparing medicine in the present embodiment is: weighs above each raw material, boiling 3 times by proportional quantity, adds for the 1st time 7 times amount water, decoct 2 hours, add 4 times amount water for the 2nd time, decoct 1.5 hours, add 2 times amount water for the 3rd time, decoct 1 hour, merge and decoct Liquid, filters, and filtrate is concentrated into the extractum that relative density is 1.35 (surveying when 60 DEG C), adds the magnesium stearate adjuvant of conventional amount used, Technique makes the medicine of tablet, specification 0.5g/ sheet routinely.
Embodiment 2
A kind of medicine treating hyopneumoniae, is made up of the component of following weight portion: Radix et Rhizoma Thalictri 138 parts, Spina Gleditsiae 16 parts, open country Flos Chrysanthemi 38 parts, Herba Violae 16 parts, Radix Scutellariae 38 parts, Radix Platycodonis 16 parts, Fructus Crataegi (parched to brown) 38 parts, Fructus Hordei Germinatus (parched to brown) 16 parts, Radix Glycyrrhizae Preparata 38 parts, the Radix Angelicae Dahuricae 28 Part, Caulis Akebiae 55 parts, Medulla Tetrapanacis 28 parts, Radix Paeoniae Rubra 55 parts, Fructus Trichosanthis 28 parts, Herba Abri 55 parts, Herba Lysimachiae 28 parts, Herba Plantaginis 55 parts.Wherein, Described Spina Gleditsiae is Spina Gleditsiae obtained by 75% ethanol solution impregnation process for using concentration.Described impregnation process is specifically, soak Take out after steeping 3 days and dry.
Process for preparing medicine in the present embodiment is: weighs above each raw material, boiling 3 times by proportional quantity, adds for the 1st time 9 times amount water, decoct 2 hours, add 4 times amount water for the 2nd time, decoct 1.5 hours, add 2 times amount water for the 3rd time, decoct 0.5 hour, merge Decocting liquid, filters, and filtrate is concentrated into the extractum that relative density is 1.25 (surveying when 60 DEG C), adds the starch supplementary material of conventional amount used, presses Common process makes the medicine of granule.
Embodiment 3
A kind of medicine treating hyopneumoniae, is made up of the component of following weight portion: Radix et Rhizoma Thalictri 27 parts, Spina Gleditsiae 27 parts, open country Flos Chrysanthemi 27 parts, Herba Violae 27 parts, Radix Scutellariae 27 parts, Radix Platycodonis 27 parts, Fructus Crataegi (parched to brown) 27 parts, Fructus Hordei Germinatus (parched to brown) 27 parts, Radix Glycyrrhizae Preparata 27 parts, the Radix Angelicae Dahuricae 47 Part, Caulis Akebiae 47 parts, Medulla Tetrapanacis 47 parts, Radix Paeoniae Rubra 47 parts, Fructus Trichosanthis 47 parts, Herba Abri 47 parts, Herba Lysimachiae 47 parts, Herba Plantaginis 47 parts.Wherein, Described Spina Gleditsiae is Spina Gleditsiae obtained by 50% ethanol solution impregnation process for using concentration.Described impregnation process is specifically, soak Take out after steeping 3 days and dry.
Process for preparing medicine in the present embodiment is: weighs above each raw material, boiling 3 times by proportional quantity, adds for the 1st time 8 times amount water, decoct 6 hours, add 5 times amount water for the 2nd time, decoct 2 hours, add 2 times amount water for the 3rd time, decoct 1 hour, collecting decoction, Filter, obtain the medicine of decoction.
Embodiment 4
A kind of medicine treating hyopneumoniae, is made up of the component of following weight portion: Radix et Rhizoma Thalictri 20 parts, Spina Gleditsiae 35 parts, open country Flos Chrysanthemi 20 parts, Herba Violae 35 parts, Radix Scutellariae 20 parts, Radix Platycodonis 35 parts, Fructus Crataegi (parched to brown) 20 parts, Fructus Hordei Germinatus (parched to brown) 35 parts, Radix Glycyrrhizae Preparata 20 parts, the Radix Angelicae Dahuricae 50 Part, Caulis Akebiae 40 parts, Medulla Tetrapanacis 50 parts, Radix Paeoniae Rubra 40 parts, Fructus Trichosanthis 50 parts, Herba Abri 40 parts, Herba Lysimachiae 50 parts, Herba Plantaginis 40 parts.Wherein, Described Spina Gleditsiae is Spina Gleditsiae obtained by 55% ethanol solution impregnation process for using concentration.Described impregnation process is specifically, soak Take out after steeping 3 days and dry.
Process for preparing medicine in the present embodiment is: weigh above each raw material, cleans and dries, and co-grinding crosses 100 mesh sieves, Obtain the medicine of powder.
Embodiment 5
A kind of medicine treating hyopneumoniae, is made up of the component of following weight portion: Radix et Rhizoma Thalictri 35 parts, Spina Gleditsiae 20 parts, open country Flos Chrysanthemi 35 parts, Herba Violae 20 parts, Radix Scutellariae 35 parts, Radix Platycodonis 20 parts, Fructus Crataegi (parched to brown) 35 parts, Fructus Hordei Germinatus (parched to brown) 20 parts, Radix Glycyrrhizae Preparata 35 parts, the Radix Angelicae Dahuricae 40 Part, Caulis Akebiae 50 parts, Medulla Tetrapanacis 40 parts, Radix Paeoniae Rubra 50 parts, Fructus Trichosanthis 40 parts, Herba Abri 50 parts, Herba Lysimachiae 40 parts, Herba Plantaginis 50 parts.Wherein, Described Spina Gleditsiae is Spina Gleditsiae obtained by 60% ethanol solution impregnation process for using concentration.Described impregnation process is specifically, soak Take out after steeping 3 days and dry.
Process for preparing medicine in the present embodiment is: weigh above each raw material, cleans and dries, and co-grinding crosses 125 mesh sieves, Add dextrin, prepare the medicine of granule.
Embodiment 6
A kind of medicine treating hyopneumoniae, is made up of the component of following weight portion: Radix et Rhizoma Thalictri 33 parts, Spina Gleditsiae 33 parts, open country Flos Chrysanthemi 33 parts, Herba Violae 33 parts, Radix Scutellariae 33 parts, Radix Platycodonis 33 parts, Fructus Crataegi (parched to brown) 33 parts, Fructus Hordei Germinatus (parched to brown) 33 parts, Radix Glycyrrhizae Preparata 33 parts, the Radix Angelicae Dahuricae 44 Part, Caulis Akebiae 44 parts, Medulla Tetrapanacis 44 parts, Radix Paeoniae Rubra 44 parts, Fructus Trichosanthis 44 parts, Herba Abri 44 parts, Herba Lysimachiae 44 parts, Herba Plantaginis 44 parts.Wherein, Described Spina Gleditsiae is Spina Gleditsiae obtained by 70% ethanol solution impregnation process for using concentration.Described impregnation process is specifically, soak Take out after steeping 3 days and dry.
The process for preparing medicine of the treatment sow chronic mammitis in the present embodiment is same as in Example 1.
Embodiment 7
A kind of medicine treating hyopneumoniae, is made up of the component of following weight portion: Radix et Rhizoma Thalictri 30 parts, Spina Gleditsiae 30 parts, open country Flos Chrysanthemi 30 parts, Herba Violae 30 parts, Radix Scutellariae 30 parts, Radix Platycodonis 30 parts, Fructus Crataegi (parched to brown) 30 parts, Fructus Hordei Germinatus (parched to brown) 30 parts, Radix Glycyrrhizae Preparata 30 parts, the Radix Angelicae Dahuricae 45 Part, Caulis Akebiae 45 parts, Medulla Tetrapanacis 45 parts, Radix Paeoniae Rubra 45 parts, Fructus Trichosanthis 45 parts, Herba Abri 45 parts, Herba Lysimachiae 45 parts, Herba Plantaginis 45 parts, wherein, Described Spina Gleditsiae is Spina Gleditsiae obtained by 65% ethanol solution impregnation process for using concentration.Described impregnation process is specifically, soak Take out after steeping 3 days and dry.
The process for preparing medicine of the treatment sow chronic mammitis in the present embodiment is same as in Example 2.
Experimental example: the medicine that the present invention the prepares clinical efficacy to hyopneumoniae.
1) experimental technique: select body weight 90 kilograms, is diagnosed as pig 120 (symptom: spirit is depressed, the food of pneumonia through veterinary Few, cough, diminished breath sound, nasal cavity stream mucus, expired gas has corrupt abnormal smells from the patient), it is equally divided into 6 groups, often group 20, is designated as respectively A, B, C, D, E, F group, often 2 courses for the treatment of of group treatment, wherein
A group is western medicine group, every day 2 times, the penicillin of pig sick to A group every injection 1,000,000 units and 1,000,000 units Streptomycin, 10 days 1 courses for the treatment of;
B group is blank group, every day 2 times, pig sick to B group every 35 milliliters of normal saline of injection, 10 days 1 courses for the treatment of;
C group is filled in the ratio of 0.2g tablet/1kg body weight and feeds the medicine of the present invention (tablet) prepared by embodiment 1, every day 2 Secondary, 10 days 1 courses for the treatment of;
D group group is filled in the ratio of 0.2g granule/1kg body weight and feeds the medicine of the present invention (granule) prepared by embodiment 2, Every day 2 times, 10 days 1 courses for the treatment of;
E group is filled in the ratio of 2ml decoction/1kg body weight and feeds the medicine of the present invention (decoction) prepared by embodiment 3, every day 2 Secondary, 10 days 1 courses for the treatment of;
F group is filled in the ratio of 0.2g powder/1kg body weight and feeds the medicine of the present invention (powder) prepared by embodiment 4, every day 2 Secondary, 10 days 1 courses for the treatment of;
2) efficacy determination
It is as the criterion according to clinical symptom disappearance, is divided into recovery from illness, effective, effective, invalid.
Recovery from illness: after treatment, physical function recovers normal completely.
Effective: after treatment, spirit takes a turn for the better, respiratory murmur is normal, and appetite is clearly better, and occurs cough once in a while, and nasal cavital mucus is significantly Reduce.
Effective: the mucus amount that treatment posterula flows out reduces, the corrupt reduced odor of exhaled gas, cough reduces.
Invalid: after treatment, symptom is without significant change, even occur cough increase the weight of, the symptom such as dyspnea.
3) curative effect is summed up
The therapeutic outcome of each experimental group such as table 1 below:
Table 1
Being not difficult to find out from the result of above-mentioned table 1, the medicine that the present invention prepares is the most remote to effective percentage and the cure rate of hyopneumoniae Being much better than Western medicine, curative effect of medication of the present invention is good, has no side effect, and does not produce drug resistance.

Claims (5)

1. the medicine treating hyopneumoniae, it is characterised in that be made up of the component of following weight portion: Radix et Rhizoma Thalictri 16~38 parts, Spina Gleditsiae 16~38 parts, Flos Chrysanthemi Indici 16~38 parts, Herba Violae 16~38 parts, Radix Scutellariae 16~38 parts, Radix Platycodonis 16~38 parts, Fructus Crataegi (parched to brown) 16 ~38 parts, Fructus Hordei Germinatus (parched to brown) 16~38 parts, Radix Glycyrrhizae Preparata 16~38 parts, the Radix Angelicae Dahuricae 28~55 parts, Caulis Akebiae 28~55 parts, Medulla Tetrapanacis 28~55 parts, Radix Paeoniae Rubra 28~55 parts, Fructus Trichosanthis 28~55 parts, Herba Abri 28~55 parts, Herba Lysimachiae 28~55 parts, Herba Plantaginis 28~55 parts.
The medicine for the treatment of hyopneumoniae the most according to claim 1, it is characterised in that be made up of the component of following weight portion: Radix et Rhizoma Thalictri 20~35 parts, Spina Gleditsiae 20~35 parts, Flos Chrysanthemi Indici 20~35 parts, Herba Violae 20~35 parts, Radix Scutellariae 20~35 parts, Radix Platycodonis 20 ~35 parts, Fructus Crataegi (parched to brown) 20~35 parts, Fructus Hordei Germinatus (parched to brown) 20~35 parts, Radix Glycyrrhizae Preparata 20~35 parts, the Radix Angelicae Dahuricae 40~50 parts, Caulis Akebiae 40~50 Part, Medulla Tetrapanacis 40~50 parts, Radix Paeoniae Rubra 40~50 parts, Fructus Trichosanthis 40~50 parts, Herba Abri 40~50 parts, Herba Lysimachiae 40~50 parts, Herba Plantaginis Grass 40~50 parts.
The medicine for the treatment of hyopneumoniae the most according to claim 1, it is characterised in that be made up of the component of following weight portion: Radix et Rhizoma Thalictri 30 parts, Spina Gleditsiae 30 parts, Flos Chrysanthemi Indici 30 parts, Herba Violae 30 parts, Radix Scutellariae 30 parts, Radix Platycodonis 30 parts, Fructus Crataegi (parched to brown) 30 parts, Fructus Hordei Germinatus (parched to brown) 30 parts, Radix Glycyrrhizae Preparata 30 parts, the Radix Angelicae Dahuricae 45 parts, Caulis Akebiae 45 parts, Medulla Tetrapanacis 45 parts, Radix Paeoniae Rubra 45 parts, Fructus Trichosanthis 45 parts, Herba Abri 45 parts, money Grass 45 parts, Herba Plantaginis 45 parts.
4. according to the medicine of the treatment hyopneumoniae described in any one of claims 1 to 3, it is characterised in that: described Spina Gleditsiae is for adopting It is Spina Gleditsiae obtained by 45%~75% ethanol solution impregnation process by concentration.
5. according to the medicine of the treatment hyopneumoniae described in any one of claims 1 to 3, it is characterised in that: described treatment sow is slow The pharmaceutical dosage form of property mastitis is any one in powder, granule, pill, tablet, decoction.
CN201610462583.9A 2016-06-22 2016-06-22 Medicine for treating pig pneumonia Pending CN105943963A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106266732A (en) * 2016-10-12 2017-01-04 扬中牧乐药业有限公司 A kind of Chinese medicine preparation treating hyopneumoniae
CN108142683A (en) * 2016-12-03 2018-06-12 灵丘县动物疫病预防控制中心 A kind of swine plague epidemic-prevention fodder and preparation method
CN110074271A (en) * 2019-03-12 2019-08-02 河北科星药业有限公司 For treating feed additive and its application of pig pneumonia

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103432374A (en) * 2013-09-10 2013-12-11 周冠旻 Medicine for treating pneumonia of pig

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103432374A (en) * 2013-09-10 2013-12-11 周冠旻 Medicine for treating pneumonia of pig

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106266732A (en) * 2016-10-12 2017-01-04 扬中牧乐药业有限公司 A kind of Chinese medicine preparation treating hyopneumoniae
CN108142683A (en) * 2016-12-03 2018-06-12 灵丘县动物疫病预防控制中心 A kind of swine plague epidemic-prevention fodder and preparation method
CN110074271A (en) * 2019-03-12 2019-08-02 河北科星药业有限公司 For treating feed additive and its application of pig pneumonia

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