CN106511812A - Medicine for treating common cold and preparation method of medicine - Google Patents

Medicine for treating common cold and preparation method of medicine Download PDF

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CN106511812A
CN106511812A CN201611149267.2A CN201611149267A CN106511812A CN 106511812 A CN106511812 A CN 106511812A CN 201611149267 A CN201611149267 A CN 201611149267A CN 106511812 A CN106511812 A CN 106511812A
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董中昌
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/287Chrysanthemum, e.g. daisy
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • A61K36/355Lonicera (honeysuckle)
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    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
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    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/534Mentha (mint)
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/538Schizonepeta
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/60Moraceae (Mulberry family), e.g. breadfruit or fig
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Abstract

The invention discloses a medicine for treating a common cold and a preparation method of the medicine. The medicine is mainly prepared from radix platycodi, herba menthae, licorice root, herba schizonepetae, honeysuckle flowers, fructus arctii, fermented soybean, fructus forsythiae, herba lophatheri, folium mori and ramulus uncariae cum uncis at a certain weight ratio. The medicine has the functions of clearing away heat and toxic materials, ventilating the inhibited lung qi, effusing the exterior and dispelling the wind, eliminating phlegm and expelling pus, dispelling wind and eliminating heat, as well as moistening lung and eliminating toxins, and is rapid in taking effect and good in curative effects when used for treating the common cold, and no relapse of the common cold occurs.

Description

It is a kind of to treat medicine of Common Cold and preparation method thereof
Technical field
The present invention relates to a kind of treat medicine of Common Cold and preparation method thereof, belong to the field of Chinese medicines.
Technical background
Common Cold is the flu caused because wind is suffered from cold, and the autumn and winter occur more.The traditional Chinese medical science is then considered that the heresy of wind and cold is outer Attack, caused by Lung Qi obstraction.Due to western medicine Common Cold large side effects, therefore Chinese medicine of the people to effectively treatment Common Cold There is great demand in medicine, up to now, it has not been found that with regard to the relevant report of the present invention.
The content of the invention
Research and the repeatedly checking of clinical trial of the present inventor according to theory of Chinese medical science, have found effectively treatment cold finally The medicine of flu, so as to complete the present invention.
It is an object of the invention to provide a kind of Chinese medicine composition of effectively treatment Common Cold.
Another object of the present invention just there is provided the preparation method of the Chinese medicine composition.
Medicine of the present invention be select Radix Platycodoniss, Herba Menthae, Radix Glycyrrhizae, Herba Schizonepetae, Flos Lonicerae, Fructus Arctii, Semen Sojae Preparatum, Fructus Forsythiae, Herba Lophatheri, Folium Mori, Ramulus Uncariae Cum Uncis, Flos Chrysanthemi, Rhizoma Cyperi medicine are combined preparation, cause each efficacy of drugs to produce collaboration these drug regimens and make With such that it is able to effectively treatment Common Cold.Its nature and flavor toil is because from Radix Platycodoniss, is put down, is entered lung, stomach, have out lung qi dispersing gas, The function of eliminating the phlegm evacuation of pus, controls exogenous cough, laryngopharynx swelling and pain, lung carbuncle pyemesis, fullness in the chest and hypochondriac pain, dysentery stomachache.It is because from Herba Menthae Its nature and flavor is pungent, cool, enters lung, Liver Channel, has dispelling wind, radiating, wards off dirty, and the function of removing toxic substances controls affection due to external wind and heat, headache, conjunctival congestion, swelling throat Bitterly, dyspepsia flatulence, aphtha, toothache, sore scabies, urticaria.Its property sweet taste is because from Radix Glycyrrhizae, enters spleen, stomach, lung meridian have with Emergency, lung moistening, removing toxic substances, the function of coordinating the actions of various ingredients in a prescription are processed with weakness of the spleen and stomach is controlled, and lack of appetite, loose stool of suffering from abdominal pain, overstrain heating, consumptive lung disease are coughed, Cardiopalmus, shy carbuncle, and raw with laryngopharynx swelling and pain is controlled, peptic ulcer, ulcer sores solve poison of drug and alimentary toxicosis.It is because from Herba Schizonepetae Its nature and flavor is pungent, temperature, enters lung, Liver Channel, delivers, wind-dispelling, the function for the treatment of blood disorderss, fries charcoal hemostasis, and cure cold heating, headache, swelling throat Bitterly, apoplexy locked mouth, spits blood, and epistaxis is had blood in stool, metrorrhagia, puerperal blood faintss, carbuncle, sore scabies, scrofula.Its property is because from Flos Lonicerae Sweet in the mouth, trembles with fear, enters lung, stomach, have heat clearing away, and the function of removing toxic substances controls warm disease heating, toxic-heat and blood stasis, carbuncle and ulcer, toxic swelling, scrofula, anal fistula. It is because that its nature and flavor is worked hard from Fructus Arctii, it is cool, enter lung, stomach, have dispelling wind and heat pathogens, lung qi dispersing rash, the function of subduing swelling and detoxicating are controlled Cough due to pathogenic wind-heat, laryngopharynx swelling and pain, macule are impermeable, and rubella is had an itch, carbuncle sore tumefacting virus.It is because that its nature and flavor is bitter from Semen Sojae Preparatum, trembles with fear, enter Lung, stomach, have and induce sweat, relieving restlessness, Xuan Yu, the function of removing toxic substances, control typhoid disease, and cold and heat, headache are fidgety, uncomfortable in chest.From Fructus Forsythiae it is Because its nature and flavor is bitter, cool, enter the heart, liver, gallbladder meridian have heat clearing away, detoxify, and eliminating stagnation, the function of detumescence control warm, erysipelas, macule, carbuncle Infectionss toxic swelling, scrofula, urine leaching closes.Its property slightly sweet flavor is because from Herba Lophatheri, is trembled with fear, enter the heart kidney two warp has clearing away heart-fire, relieving restlessness Heat, the function of diuresis, it is thirsty to control calentura, vexed, hot urination, stranguria with turbid discharge, erosion of the oral mucosa tongue boil, gingival swelling and pain.From Folium Mori be because For its nature and flavor bitter sweet, tremble with fear, enter lung, Liver Channel, have expelling wind and clearing away heat, the function of cooling blood for improving eyesight, dispelling the wind and dampness pathogens heating, headache, conjunctival congestion, mouth Yearningly, cough due to lung-heat, migratory arthralgia, urticaria, lower limb elephatiasis.It is because that its nature and flavor is bitter from Ramulus Uncariae Cum Uncis, cool, enter liver, heart channel have heat clearing away to put down Liver, the function of the arresting convulsion that relieves dizziness, high fever, infantile convulsions, epilepsy, etc. are controlled children and shy, and adult's slight Hypertension is dizzy, dizzy, Fu Renzi.From Flos Chrysanthemi be because It is for its nature and flavor sweetness and bitterness, cool, enter lung, Liver Channel has dispelling wind, and disappear heat, improving eyesight, the function of removing toxic substances, controls headache, and dizziness, conjunctival congestion, ambition are tired of Heat, furuncle, toxic swelling.It is because that the pungent slight bitter of its nature and flavor is done from Rhizoma Cyperi, puts down, enter liver, tri-jiao channel has Regulate the flow of vital energy Xie Yu, pain relieving regulating menstruation Function, control incoordination between the liver and stomach, depression of QI, chest and abdomen distending pain over the hypochondrium, phlegm retention feeling of fullness, menoxenia, bleeding not during menses.
Specific embodiment
The drug dose of instant component be also inventor through groping in a large number to summarize what is drawn, the consumption of each component is following heavy All there is in the range of amount preferable curative effect:
15-25 gram of Radix Platycodoniss, 15-25 gram of Herba Menthae, 5-15 gram of Radix Glycyrrhizae, 15-25 gram of Herba Schizonepetae, 15-25 gram of Flos Lonicerae, Fructus Arctii 5-15 Gram, 10-20 gram of Semen Sojae Preparatum, 5-15 gram of Fructus Forsythiae, 5-15 gram of Herba Lophatheri, 15-25 gram of Folium Mori, 5-15 gram of Ramulus Uncariae Cum Uncis, 15-25 gram of Flos Chrysanthemi, 5-15 gram of Rhizoma Cyperi.
Preferably:
20 grams of Radix Platycodoniss, 20 grams of Herba Menthae, 10 grams of Radix Glycyrrhizae, 20 grams of Herba Schizonepetae, 20 grams of Flos Lonicerae, 10 grams of Fructus Arctii, 15 grams of Semen Sojae Preparatum, Fructus Forsythiae 10 grams, 10 grams of Herba Lophatheri, 20 grams of Folium Mori, 10 grams of Ramulus Uncariae Cum Uncis, 20 grams of Flos Chrysanthemi, 10 grams of Rhizoma Cyperi.
The preparation method of medicine of the present invention is as follows
First, get the raw materials ready
1st, Radix Platycodoniss:Net impurity is picked, except removing LU, is cleaned and is pulled out, cut into slices after running through, dry;
2nd, Herba Menthae:Pick net impurity, remove undesirable root, first by leaf tremble it is lower separately put, stem is sprayed into clear water then, rear cutting is run through, is dried, Again with leaf and even;
3rd, Radix Glycyrrhizae:Pick impurity, clean, be soaked in water to eighty per cant it is saturating when, pull out, run through, cut into slices, dry;
4th, Herba Schizonepetae:Net impurity is picked, is slightly steeped with water, pull cutting out, dried;
5th, Flos Lonicerae:Silt is weeded out, net impurity is picked;
6th, Fructus Arctii:Impurity is picked, spare is weeded out;
7th, Semen Sojae Preparatum:Original is used as medicine;
8th, Fructus Forsythiae:Net impurity is picked, stranding is opened, except discarding stalk;
9th, Herba Lophatheri:Impurity and root are picked, cutting is dried;
10th, Folium Mori:Impurity is picked, is rubbed broken with the hands, is winnowed with a dustpan destemming, weed out spare;
11st, Ramulus Uncariae Cum Uncis:Old stalk, impurity are picked, is cleaned, is dried;
12nd, Flos Chrysanthemi:Pick net leaf stalk, anthocaulus and spare impurity;
13rd, Rhizoma Cyperi:Impurity is picked, particle is ground into, winnow with a dustpan fine, soft fur and smalls.
2nd, prepare
1. by the Radix Platycodoniss for cooking, Herba Menthae, Radix Glycyrrhizae, Herba Schizonepetae, Flos Lonicerae, Fructus Arctii, Semen Sojae Preparatum, Fructus Forsythiae, Herba Lophatheri, Folium Mori, hook Rattan, Flos Chrysanthemi, Rhizoma Cyperi are put in decocting container and add water to cook secondary, add water for the first time 8 times and measure, and decoct 1.5 hours, add water for the second time 6 times of amounts are decocted 1 hour, are merged decoction liquor twice, are filtered to get filtrate;
2. filtrate is condensed into into the extractum that proportion is 1.35, extractum plus 90%-95% ethanol is carried out into precipitate with ethanol, recovery ethanol is simultaneously dense Contracting, is dried at 45-50 DEG C, and dry extract is obtained;
3. dry extract is broken into into fine powder, adds adjuvant to make granule, it is tabletted, per 0.5 gram of piece.
Flos Lonicerae heat-clearing and toxic substances removing in prescription, controls warm disease heating for monarch drug;Radix Platycodoniss open lung qi dispersing gas, and eliminating the phlegm evacuation of pus, Herba Schizonepetae are delivered, Wind-dispelling, treating blood disorderss, the two is ministerial drug, and three taste medicines play jointly heat-clearing and toxic substances removing, open lung qi dispersing gas, delivers wind-dispelling, the effect of eliminating the phlegm evacuation of pus, Treatment Common Cold effect comprehensively, and with heat-clearing and toxic substances removing, opens lung qi dispersing gas, and delivering wind-dispelling master can effect a permanent cure, and Flos Chrysanthemi has dispelling wind, and disappear heat, Improving eyesight, the function of removing toxic substances is adjuvant drug, Radix Glycyrrhizae and middle emergency, lung moistening, removing toxic substances, and to make medicine, all medicines are to take stopgap measures to coordinating the actions of various ingredients in a prescription with being left.
Medicine of the present invention has heat-clearing and toxic substances removing, opens lung qi dispersing gas, delivers wind-dispelling, eliminating the phlegm evacuation of pus, and dispelling wind disappears heat, lung moistening removing toxic substances Function, for treating Common Cold, short treating period, instant effect, non-relapse after healing.
Specific embodiment:
The beneficial effect of medicine of the present invention is expanded on further below by way of test example, these test examples include medicine of the present invention The animal toxicity test report of thing and clinical observation on the therapeutic effect data.
The animal toxicity test report of [test example 1] medicine of the present invention:
Rabbit 30 is taken, male and female dual-purpose, 2.0 2.5kg of body weight are divided to two groups, 15 per group, one of which is tested for overdose Group, another group is normal amount test group.Super quantity group oral tablet be 0.1g/kg, normal amount group be 0.05g/kg, administering mode To dilute administration by gavage administration, twice daily, 7 days are serve on, as a result the reaction of observation administration daily shows two groups of rabbit activities, diet Normally, medicine is without bad toxic and side effects.
The clinical observation on the therapeutic effect of [test example 2] medicine of the present invention
1st, physical data
Accept Common Cold out-patient totally 31 for medical treatment.
2nd, diagnostic criteria
The symptom of Common Cold is nasal obstruction, watery nasal discharge, sneeze, cough, aversion to cold, heating or tired, general malaise etc..
3rd, Therapeutic Method
From above-mentioned medicament, take to patient, each take 2 grams of tablet, it is early, middle and late daily respectively to take 1 time, treat for one within 5 days Journey, continuously takes 1 course for the treatment of.
4th, efficacy assessment standard
It is effective:Common Cold symptom disappears, and body constitution gradually recovers normal, fully recovers;
Take a turn for the better:Patient's nasal obstruction watery nasal discharge, fever with aversion to cold take a turn for the better;The phenomenons such as tired, general malaise mitigate;
It is invalid:Improvement standard person is not reached.
5th, therapeutic outcome(See the table below)
In above-mentioned treatment, with Drug therapy cold patient of the present invention 31, as a result effective 25, obvious effective rate is 80.65%, take a turn for the better 5, improvement rate is 16.13%, and invalid 1, total effective rate is 96.78%.

Claims (3)

1. a kind of medicine for treating Common Cold, it is characterised in that:It is made up of the crude drug in following weight range:
15-25 gram of Radix Platycodoniss, 15-25 gram of Herba Menthae, 5-15 gram of Radix Glycyrrhizae, 15-25 gram of Herba Schizonepetae, 15-25 gram of Flos Lonicerae, Fructus Arctii 5-15 Gram, 10-20 gram of Semen Sojae Preparatum, 5-15 gram of Fructus Forsythiae, 5-15 gram of Herba Lophatheri, 15-25 gram of Folium Mori, 5-15 gram of Ramulus Uncariae Cum Uncis, 15-25 gram of Flos Chrysanthemi, 5-15 gram of Rhizoma Cyperi.
2. medicine according to claim 1, wherein the consumption of each crude drug is:
20 grams of Radix Platycodoniss, 20 grams of Herba Menthae, 10 grams of Radix Glycyrrhizae, 20 grams of Herba Schizonepetae, 20 grams of Flos Lonicerae, 10 grams of Fructus Arctii, 15 grams of Semen Sojae Preparatum, Fructus Forsythiae 10 grams, 10 grams of Herba Lophatheri, 20 grams of Folium Mori, 10 grams of Ramulus Uncariae Cum Uncis, 20 grams of Flos Chrysanthemi, 10 grams of Rhizoma Cyperi.
3. the preparation method of medicine according to claim 1 or claim 2, it comprises the following steps:
(One)Get the raw materials ready
(1)Radix Platycodoniss:Net impurity is picked, except removing LU, is cleaned and is pulled out, cut into slices after running through, dry;
(2)Herba Menthae:Pick net impurity, remove undesirable root, first by leaf tremble it is lower separately put, stem is sprayed into clear water then, rear cutting is run through, is shone It is dry, then with leaf and even;
(3)Radix Glycyrrhizae:Pick impurity, clean, be soaked in water to eighty per cant it is saturating when, pull out, run through, cut into slices, dry;
(4)Herba Schizonepetae:Net impurity is picked, is slightly steeped with water, pull cutting out, dried;
(5)Flos Lonicerae:Silt is weeded out, net impurity is picked;
(6)Fructus Arctii:Impurity is picked, spare is weeded out;
(7)Semen Sojae Preparatum:Original is used as medicine;
(8)Fructus Forsythiae:Net impurity is picked, stranding is opened, except discarding stalk;
(9)Herba Lophatheri:Impurity and root are picked, cutting is dried;
(10)Folium Mori:Impurity is picked, is rubbed broken with the hands, is winnowed with a dustpan destemming, weed out spare;
(11)Ramulus Uncariae Cum Uncis:Old stalk, impurity are picked, is cleaned, is dried;
(12)Flos Chrysanthemi:Pick net leaf stalk, anthocaulus and spare impurity;
(13)Rhizoma Cyperi:Impurity is picked, particle is ground into, winnow with a dustpan fine, soft fur and smalls;
(Two)Prepare
1. by the Radix Platycodoniss for cooking, Herba Menthae, Radix Glycyrrhizae, Herba Schizonepetae, Flos Lonicerae, Fructus Arctii, Semen Sojae Preparatum, Fructus Forsythiae, Herba Lophatheri, Folium Mori, hook Rattan, Flos Chrysanthemi, Rhizoma Cyperi are put in decocting container and add water to cook secondary, add water for the first time 8 times and measure, and decoct 1.5 hours, add water for the second time 6 times of amounts are decocted 1 hour, are merged decoction liquor twice, are filtered to get filtrate;
2. filtrate is condensed into into the extractum that proportion is 1.35, extractum plus 90%-95% ethanol is carried out into precipitate with ethanol, recovery ethanol is simultaneously dense Contracting, is dried at 45-50 DEG C, and dry extract is obtained;
3. dry extract is broken into into fine powder, adds adjuvant to make granule, it is tabletted, per 0.5 gram of piece.
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107582791A (en) * 2017-10-29 2018-01-16 杨小丽 A kind of medicine for treating amenorrhoea and preparation method thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
中华人民共和国卫生部药典委员会: "《中华人民共和国卫生部药品标准中药成方制剂(第十一册)》", 31 December 1996 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107582791A (en) * 2017-10-29 2018-01-16 杨小丽 A kind of medicine for treating amenorrhoea and preparation method thereof

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