CN106620408A - Medicine for treating malignant hydatid form moles and preparation method thereof - Google Patents
Medicine for treating malignant hydatid form moles and preparation method thereof Download PDFInfo
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- CN106620408A CN106620408A CN201710185876.1A CN201710185876A CN106620408A CN 106620408 A CN106620408 A CN 106620408A CN 201710185876 A CN201710185876 A CN 201710185876A CN 106620408 A CN106620408 A CN 106620408A
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Abstract
The invention discloses a medicine for treating malignant hydatid form moles and a preparation method thereof. The medicine is mainly prepared, on the basis of certain weight ratio, codonopsis pilosula, lithospermum erythrorhizon, herba leonuri, radix sophorae tonkinensis, rhubarb, oldenlandia diffusa, cassia twigs, licorice roots, pteris multifida, trogopterus dung, melia toosendan, red peony roots, sculellaria barbata, peach kernels, leaves of mahonia fortunei, solanum nigrum, moutan bark, poria cocos, flos carthami, fructus forsythia, rhizoma chuanxiong, trichosanthes kirilowii and coix seeds. The medicine has the effects of tonifying the middle to boost qi, engendering fluid, clearing heat and tonifying deficiency, activating blood to dispersing stasis, fortifying spleen and tonifying lung, and has quick and good effect when being used for treating the malignant hydatid form moles without relapse.
Description
Technical field
The present invention relates to a kind of treat medicine of chorioadenoma and preparation method thereof, belong to the field of Chinese medicines.
Background technology
Chorioadenoma refers to placental villi trophoblast hyperplasia after gestation, and interstitial is treating serious edema caused, is formed not of uniform size
Bubble, be connected bunchiness between bubble, shape such as grape, also known as hydatidiform mole（HM）.The traditional Chinese medical science then thinks chorioadenoma and deficiency of vital energy blood
The stasis of blood, lung yin is damaged relevant.Because western medicine large side effects, therefore people are deposited to the Chinese medicine of effectively treatment chorioadenoma
In great demand, up to now, it has not been found that with regard to the relevant report of the present invention.
The content of the invention
The present inventor have found effectively treatment pernicious finally according to the checking repeatedly of research and the clinical testing of theory of traditional Chinese medical science
The medicine of vesicular mole, so as to complete the present invention.
It is an object of the invention to provide a kind of Chinese medicine composition of effectively treatment chorioadenoma.
Another object of the present invention just there is provided the preparation method of the Chinese medicine composition.
Medicine of the present invention is to select Radix Codonopsis, Asian puccoon, motherwort, subprostrate sophora, rheum officinale, oldenlandia diffusa, cassia twig, Radix Glycyrrhizae, phoenix
Tail grass, excrementum pteropi, Fructus meliae toosendan, the radix paeoniae rubrathe, Sculellaria barbata, peach kernel, Chinese mahonia leaf, black nightshade, moutan bark, Poria cocos, safflower, the capsule of weeping forsythia, river
Rhizome of chuanxiong, Snakegourd Fruit, coix seed, the bighead atractylodes rhizome, cattail pollen are combined preparation, cause each efficacy of drugs to produce collaboration these drug regimens and make
With such that it is able to effectively treatment chorioadenoma.Wherein it is because that its nature and flavor is sweet from Radix Codonopsis, puts down, starts with, meridian of Foot-TAI YIN gas
Point, there is tonifying middle-Jiao and Qi, the function of promoting the production of body fluid controls weakness of the spleen and the stomach, and qi-blood deficiency, body is tired powerless, and deficiency of food is thirsty, chronic diarrhea, prolapse of the anus.Choosing
Its nature and flavor being because with Asian puccoon earnestly, being trembled with fear, enter percardium, Liver Channel, there is cool blood, invigorated blood circulation, clearing heat and detoxicating function controls warm spot
Rash, jaundice with damp-heat pathogen, purpura tells, is defeated in battle, hematuria, stranguria with turbid discharge, bloody flux, constipation with heat retention, burn, eczema, erysipelas, large carbuncle.From motherwort
It is because that its nature and flavor is worked hard, it is cool, enter pericardium, Liver Channel, there is promoting blood circulation, dissolving stasis, menstruation regulating, the function of the water that disappears controls irregular menstruation, controls Lou difficult
Produce, placenta retension, postpartum anemic fainting, abdominal pain due to blood stasis, metrorrhagia and metrostaxis, hematuria rushes down blood, carbuncle swells sore.It is because from subprostrate sophora
Nature and flavor are bitter, tremble with fear, and enter the heart, lung, the Jing of large intestine three relieve inflammation or internal heat, and removing toxic substances, detumescence, the function of pain relieving controls retropharyngeal abscess, sore-throat, larynx numbness, gum
Swell and ache, breathe heavily full heat and cough, jaundice, diarrhea, haemorrhoids, heat is swollen, the favus of the scalp, mange, snake, worm, dog bite.Its nature and flavor is because from rheum officinale
It is bitter, cold, enter stomach, large intestine, liver footpath, there is the poison that purges heat, break stagnant, the function of row hemostasis controls real heat constipation, and delirious speech is gone mad, dyspepsia ruffian
It is full, dysentery from the beginning of, tenesmus, stasis of blood menopause Bi ， lumps in the chest and abdomen, when the hot epidemic disease of row, sudden and violent swelling ophthalmalgia spits blood, bleeding from five sense organs or subcutaneous tissue, yang jaundice, oedema,
Stranguria with turbid discharge, urinates red, large carbuncle pyogenic infections, furunculosis, burn.Its nature and flavor bitter sweet is because from oldenlandia diffusa, is trembled with fear, enter the heart, liver, spleen three
Jing, there is a heat-clearing, dampness removing, the function of removing toxic substances, controls dyspnea and cough due to lung-heat, tonsillitis, sphagitis, appendicitis, dysentery, jaundice, pelvic infecton,
Adnexitis, carbuncle swells furunculosis, venomous snake bite.Its property acrid-sweet flavor is because from cassia twig, temperature enters bladder, the heart, lung channel, there is sweating solution
Flesh, the function of warming meridians and promoting circulation of qi controls exterior syndrome due to wind-cold, shoulder back of the body podomere ache, obstruction of qi in the chest phlegm and retained fluid, Jing Bi Disorder lumps in the abdomen.It is because from Radix Glycyrrhizae
Nature and flavor are sweet, put down, and enter spleen, stomach, lung channel, have and middle emergency, moistening lung, detoxify, and the function of coordinating the drug actions of a prescription is processed use, controls weakness of the spleen and the stomach, eat
It is few, loose stool of suffering from abdominal pain, overstrain heating, consumptive lung disease cough, palpitaition ， Jing Epilepsy；It is raw to use, control abscess of throat, peptic ulcer, ulcer sores,
Antidote poison and food poisoning.The light slight bitter of its nature and flavor is because from phoenix-tail fern, is trembled with fear, enter kidney, the Jing of stomach two, there is clearing heat and promoting diuresis, cool blood
Hemostasis, the function of subdhing swelling and detoxicating controls icteric hepatitis, and enteritis, bacillary dysentery, stranguria with turbid discharge, under band is spitted blood, and bleeding from five sense organs or subcutaneous tissue is had blood in stool, hematuria, almond
Body is scorching, parotitis, carbuncle sore tumefacting virus, eczema.Its nature and flavor bitter sweet is because from excrementum pteropi, temperature, enter liver, the spleen channel are raw with there is promoting circulation of blood
The function of pain relieving, controls all pains of trusted subordinate's vim and vigour, and women's Amenorrhea, postpartum blood stasis are had a pain；Snake, scorpion, centipde-bite are controlled outward, and stir-fry is stopped blooding,
Metrorrhagia is controlled, menorrhagia, leukorrhea with bloody discharge is without cease.It is because that its nature and flavor is bitter from Fructus meliae toosendan, trembles with fear, poisonous, enter liver, stomach, small intestinl channel,
There is wet down heat, clearing away the liver-fire, pain relieving, the function of desinsection controls pyretic epigastralgia, hypochondriac pain, colic, abdominal pain due to enterositosis.It is because from the radix paeoniae rubrathe
Its nature and flavor is bitter, is slightly cold, and return liver warp has clearing heat and cooling blood, and the function of blood stasis removing analgesic is controlled warm poison and gone mad, hematemesis and epistaxis, red eye, swell pain,
Liver-depressed hypochondrium pain, Amenorrhea dysmenorrhoea ， Epilepsy lump in the abdomen stomachache, injury from falling down, carbuncle swells sore.It is because that its nature and flavor is bitter from Sculellaria barbata, trembles with fear have clear
Heat, the function of removing toxic substances controls abscess of throat, scalds, traumatic injury, wet sore.Its nature and flavor bitter sweet is because from peach kernel, is put down, enter the heart,
Liver, large intestine channel, there is the blood-breaking row stasis of blood, moisturize sliding Jing functions, and controlling through closing ， Disorder lumps in the abdomen, pyreticosis stores blood, blood-arthralgia, malaria, traumatic injury, the stasis of blood
Hemotoncus pain, the dry constipation of blood.It is because that its nature and flavor is bitter from Chinese mahonia leaf, it is cool, enter lung channel, there is heat-clearing qi-restoratives, it is relieving cough and reducing sputum
Function, control tuberculosis hemoptysis, osteopyrexia and fever, dizziness and tinnitus, waist soreness is vexed, hot eyes.Its nature and flavor is because from black nightshade
Hardship, trembles with fear, and has heat-clearing, detoxifies, and promoting blood circulation, the function of detumescence controls furunculosis, carbuncle swells, erysipelas, osteopatia sprain, chronic bronchitis, acute kidney
It is scorching.It is because that its nature and flavor is worked hard from moutan bark, cool, enter the heart, liver and kidney channel have heat-clearing, cool blood, and blood, and the function of disappear the stasis of blood is controlled
Heat invading xuefen, sends out spot ， Jing Epilepsy, tells, is defeated in battle, has blood in stool, and hectic fever due to yin labor heat, Amenorrhea ， Disorder lumps in the abdomen, large carbuncle flutters damage.Its property is because from Poria cocos
Slightly sweet flavor, puts down, and enter the heart, spleen, lung channel have eliminating dampness and diuresis, and beneficial spleen and stomach, the function of antitoxic heart-soothing and sedative controls difficult urination oedema distending pain,
Phlegm and retained fluid coughs inverse, the sound of vomiting of vomitting, and has loose bowels, seminal emission, stranguria with turbid discharge, and palpitation with fear is forgetful.It is because that its nature and flavor is pungent from safflower, temperature, enter the heart, Liver Channel have
Invigorate blood circulation, the function of stasis eliminatings pain relieving, controlling through closing ， Disorder lumps in the abdomen, difficult labour, stillborn foetus, disease that postpartum lochia can't go, hemostasis is had a pain, and carbuncle swells are fallen and flutterred
Damage.It is because that its nature and flavor is bitter from the capsule of weeping forsythia, cool, enter the heart, liver, gallbladder channel have heat-clearing, detoxifies, dissipating bind, the function of detumescence controls temperature
Heat, erysipelas, macula, large carbuncle pyogenic infections, scrofula, urine leaching closes.It is because that its nature and flavor is pungent from Ligusticum wallichii, temperature, enter liver, gallbladder channel have row
Gas opens strongly fragrant, dispels pathogenic wind and remove dampness, the function of promoting blood circulation and stopping pain, controls air-cooled headache rotation and swoons, and hypochondriac pain abdomen pain, arthritis muscle contraction, Amenorrhea, difficult labour is produced
Afterwards stasis blocking block pain, ulcer sores.It is because that its nature and flavor is sweet, slight bitter from Snakegourd Fruit, trembles with fear, return lung, stomach, large intestine channel has clearing away heat and eliminating phlegm,
Relieving stuffiness of the chest by dispersing aggregation of pathogens, the function of moisturize laxation controls cough with lung heat, and the turbid Huang of phlegm is thick, chest impediment and cardialgia, accumulation of pathogens in chest feeling of fullness, acute mastitis, acute appendicitis, stool
It is constipated.Its property slightly sweet flavor is because from coix seed, it is cool, enter spleen, lung, kidney channel, there is an invigorating the spleen, tonifying lung, heat-clearing, the function of dampness removing,
Control and have loose bowels, arthritis with fixed pain caused by dampness, muscle arteries and veins contraction, joint stuffiness, oedema, tinea pedis, consumptive lung disease, lung carbuncle, acute appendicitis, stranguria with turbid discharge, leukorrhea.From the bighead atractylodes rhizome be because
For its nature and flavor bitter sweet, temperature enters spleen, stomach, there is a tonifying spleen, beneficial stomach, eliminating dampness, and in function, control deficient QI of the spleen and stomach, do not feel like eating is tired
Idle few gas, it is empty swollen, to have loose bowels, phlegm and retained fluid, oedema, jaundice, arthritis with fixed pain caused by dampness, difficult urination is dizzy, and spontaneous perspiration, nausea is uneasy.From cattail pollen be because
Sweet arduous, cool, enter liver, the heart channel of Hang-Shaoyin for its nature and flavor, there is cooling blood and hemostasis, and the function of activating blood circulation and dissipating blood stasis, raw controlling through closing is suffered from abdominal pain, postpartum stasis
Have a pain, fall vexed, sore furuncle poison of flutterring blood, fry black antiemetic blood, blood is rushed down in bleeding from five sense organs or subcutaneous tissue, uterine bleeding, and hematuria, bloody flux, under band controls outward double tongue, mouth
Sore, Ting discharging ear, bleeding in ear, uncontrolled urination.
Specific embodiment
The drug dose of instant component is also that inventor summarizes what is drawn through groping in a large number, and the consumption of each component is following heavy
All there is preferable curative effect in the range of amount：
15-25 gram of Radix Codonopsis, 15-20 gram of Asian puccoon, 10-20 gram of motherwort, 15-20 gram of subprostrate sophora, 10-20 gram of rheum officinale, oldenlandia
Careless 15-20 gram, 10-20 gram of cassia twig, 10-15 gram of Radix Glycyrrhizae, 15-25 gram of phoenix-tail fern, 10-15 gram of excrementum pteropi, 10-20 gram of Fructus meliae toosendan,
5-10 gram of the radix paeoniae rubrathe, 15-25 gram of Sculellaria barbata, 10-20 gram of peach kernel, 15-25 gram of Chinese mahonia leaf, 10-20 gram of black nightshade, moutan bark 10-
20 grams, 10-15 gram of Poria cocos, 10-20 gram of safflower, 10-20 gram of the capsule of weeping forsythia, 5-10 gram of Ligusticum wallichii, 15-25 gram of Snakegourd Fruit, coix seed 10-20
Gram, 10-15 gram of the bighead atractylodes rhizome, 5-10 gram of cattail pollen.
Preferably：
20 grams of Radix Codonopsis, 18 grams of Asian puccoon, 15 grams of motherwort, 18 grams of subprostrate sophora, 15 grams of rheum officinale, 18 grams of oldenlandia diffusa, 15 grams of cassia twig,
12 grams of Radix Glycyrrhizae, 20 grams of phoenix-tail fern, 12 grams of excrementum pteropi, 15 grams of Fructus meliae toosendan, 8 grams of the radix paeoniae rubrathe, 20 grams of Sculellaria barbata, 15 grams of peach kernel, ten big work(
20 grams of labor leaf, 15 grams of black nightshade, 15 grams of moutan bark, 12 grams of Poria cocos, 15 grams of safflower, 15 grams of the capsule of weeping forsythia, 8 grams of Ligusticum wallichii, 20 grams of Snakegourd Fruit, Job's tears
15 grams of benevolence, 12 grams of the bighead atractylodes rhizome, 8 grams of cattail pollen.
The preparation method of medicine of the present invention is as follows
First, get the raw materials ready
1st, Radix Codonopsis：Reed, section or segment are run through after clean silt, is dried；
2nd, Asian puccoon：Clean, run through, cut into slices, dry；
3rd, motherwort：Impurity is picked, is cleaned, run through, segment is dried；
4th, subprostrate sophora：Net impurity is picked, thickness stepping is soaked in water, pulls out, cut into slices after running through, dried；
5th, rheum officinale：Net impurity is picked, size stepping, vexed profit to inside and outside humidity is uniform, cuts into slices or is cut into small pieces, dries；
6th, oldenlandia diffusa：Crude drug is taken, impurity is removed, wash quickly is net, slightly dries in the air, segment is dried, and weeds out grey bits；
7th, cassia twig：Slightly soaked with water, pulled out, it is vexed to moisten to saturating, section, dry, weed out bits；
8th, Radix Glycyrrhizae：Pick impurity, clean, be soaked in water to eighty per cant it is saturating when, pull out, run through section, dry；
9th, phoenix-tail fern：The soil on surface is removed after adopting, is cleaned, dried；
10th, excrementum pteropi：Net impurity is picked, grey bits are smashed or weed out；
11st, Fructus meliae toosendan：Impurity is picked, is cleaned, drying or is split into two halves at grating；
12nd, the radix paeoniae rubrathe：Crude drug is taken, impurity is removed, size stepping is cleaned, run through, shave, is dried, and weeds out chip；
13rd, Sculellaria barbata：Impurity is removed, is cleaned, slightly moistened, segment, be dried；
14th, peach kernel：Duricrust impurity is removed, is put in boiling water pot and is boiled to crust microcreping, pulled out, in immersion cold water, kind of a skin is removed in stranding, is shone
It is dry, winnow with a dustpan net；
15th, Chinese mahonia leaf：Autumn harvests, and picks net impurity, dries；
16th, black nightshade：Crude drug is taken, old stalk, impurity is removed, is cleaned, slightly moistened, segment, be dried；
17th, moutan bark：Impurity is picked, core is removed, is cleaned, run through, cut into slices, dried；
18th, Poria cocos：Be soaked in water, clean pull out, it is vexed after, cut into slices, dry；
19th, safflower：Net impurity is picked, cauline leaf, base of a fruit head is removed, is dried；
20th, the capsule of weeping forsythia：Net impurity is picked, stranding is opened, except discarding stalk；
21st, Ligusticum wallichii：Impurity is picked, separates large and small, be soaked in water, solarization is dried in the air, cut into slices after vexed profit, be dried；
22nd, Snakegourd Fruit：Crude drug, removing impurity and carpopodium, clean, flattening, chopping or fritter are taken, is dried；
23rd, coix seed：Crude drug is taken, residual cot, impurity is removed；
24th, the bighead atractylodes rhizome：Net impurity is picked, is soaked in water, pulled out after bubble, run through, cut into slices, dried；
25th, cattail pollen：Broken caking is rubbed, is sieved, remove impurity.
2nd, prepare
1st, by the Radix Codonopsis of the weight, Asian puccoon, motherwort, subprostrate sophora, rheum officinale, oldenlandia diffusa, cassia twig, Radix Glycyrrhizae, phoenix-tail fern, five
Clever fat, Fructus meliae toosendan, the radix paeoniae rubrathe, Sculellaria barbata, peach kernel, Chinese mahonia leaf, black nightshade, moutan bark, Poria cocos, safflower, the capsule of weeping forsythia, Ligusticum wallichii, Snakegourd Fruit,
Coix seed, the bighead atractylodes rhizome, cattail pollen are put in decocting container, are added water for the first time 8 times and are measured, and after soaking 100 minutes, are fried by intense fire to boil and are risen, then
With being cooked by slow fire 20 minutes, first time decoction liquor is filtered to obtain, first time decoction liquor is poured in container；
2nd, the dregs of a decoction of filtration are added water 6 times and is measured, boiled by intense fire, then with being cooked by slow fire 20 minutes, filter to obtain second decoction liquor；
3rd, will decoction liquor mixing and stirring twice, be divided into 3 doses and take.
Radix Codonopsis has tonifying middle-Jiao and Qi in prescription, and the function of promoting the production of body fluid is monarch drug in a prescription；Chinese mahonia leaf heat-clearing qi-restoratives is relieving cough and reducing sputum；Pu
Huang has a cooling blood and hemostasis, the function of activating blood circulation and dissipating blood stasis, and the two is ministerial drug, and three taste medicines play tonifying middle-Jiao and Qi, promote the production of body fluid jointly, heat-clearing qi-restoratives,
Promoting blood circulation disappears silts, relieving cough and reducing sputum effect, and treatment chorioadenoma effect is comprehensive, and with clearing heat and promoting fluid, can control based on middle benefit gas promoting the circulation of qi
This, Radix Glycyrrhizae has and middle emergency, moistening lung, removing toxic substances, and the function of coordinating the drug actions of a prescription is adjutant, and coix seed has invigorating the spleen, tonifying lung, heat-clearing, dampness removing
Function to make medicine, all medicines are to take stopgap measures with being left.
Medicine of the present invention has tonifying middle-Jiao and Qi, promotes the production of body fluid, heat-clearing qi-restoratives, the silt that disappears of invigorating blood circulation, the function of strengthening the spleen and tonifying the lung, for treating
Chorioadenoma, short treating period, instant effect, non-relapse after healing.
The beneficial effect of medicine of the present invention is expanded on further below by way of test example, these test examples are including this
The animal toxicity test report of bright medicine and clinical observation on the therapeutic effect data.
The animal toxicity test report of [test example 1] medicine of the present invention：
Rabbit 30 is taken, male and female dual-purpose, 2.0-2.5kg of body weight is divided to two groups, and 15 per group, one of which is overdose test
Group, another group is normal amount test group.Super quantity group is 20ml/kg, and normal amount is 10ml/kg, and administering mode is given for administration by gavage
Medicine, twice daily, serve on 7 days, the reaction of observation administration daily, as a result shows that two groups of rabbit activities, diet are normal, and medicine is without bad
Toxic and side effect.
The clinical observation on the therapeutic effect of [test example 2] medicine of the present invention
1st, physical data
Accept chorioadenoma out-patient totally 17 for medical treatment.
2nd, diagnostic criteria
Classical symptom is amenorrhoea, colporrhagia, uterus increase, stomachache, spitting of blood, gestosis, anaemia and infection.
3rd, treatment method
From above-mentioned medicament, take to patient, each take 1 dose, early daily, evening respectively takes 1 time, be within 7 days a course for the treatment of, continuously clothes
With 2 courses for the treatment of.
4th, efficacy assessment standard
It is effective：Chorioadenoma symptom disappears, recovery from illness；
Take a turn for the better：The phenomenon of patient's amenorrhoea, colporrhagia, uterus increase, stomachache, spitting of blood, gestosis, anaemia and infection mitigates,
Progressively recover normal；
It is invalid：Improvement standard person is not reached.
5th, treatment results（See the table below）
In above-mentioned treatment, with drug therapy chorioadenoma patient 17 of the present invention, as a result effective 13, obvious effective rate is
76.47%, take a turn for the better 3, improvement rate is 17.64%, and invalid 1, total effective rate is 94.11%.
Claims (3)
1. a kind of medicine for treating chorioadenoma, it is characterised in that：It is made up of the bulk drug in following weight range：
15-25 gram of Radix Codonopsis, 15-20 gram of Asian puccoon, 10-20 gram of motherwort, 15-20 gram of subprostrate sophora, 10-20 gram of rheum officinale, oldenlandia
Careless 15-20 gram, 10-20 gram of cassia twig, 10-15 gram of Radix Glycyrrhizae, 15-25 gram of phoenix-tail fern, 10-15 gram of excrementum pteropi, 10-20 gram of Fructus meliae toosendan,
5-10 gram of the radix paeoniae rubrathe, 15-25 gram of Sculellaria barbata, 10-20 gram of peach kernel, 15-25 gram of Chinese mahonia leaf, 10-20 gram of black nightshade, moutan bark 10-
20 grams, 10-15 gram of Poria cocos, 10-20 gram of safflower, 10-20 gram of the capsule of weeping forsythia, 5-10 gram of Ligusticum wallichii, 15-25 gram of Snakegourd Fruit, coix seed 10-20
Gram, 10-15 gram of the bighead atractylodes rhizome, 5-10 gram of cattail pollen.
2. medicine according to claim 1, wherein the consumption of each bulk drug is：
20 grams of Radix Codonopsis, 18 grams of Asian puccoon, 15 grams of motherwort, 18 grams of subprostrate sophora, 15 grams of rheum officinale, 18 grams of oldenlandia diffusa, 15 grams of cassia twig,
12 grams of Radix Glycyrrhizae, 20 grams of phoenix-tail fern, 12 grams of excrementum pteropi, 15 grams of Fructus meliae toosendan, 8 grams of the radix paeoniae rubrathe, 20 grams of Sculellaria barbata, 15 grams of peach kernel, ten big work(
20 grams of labor leaf, 15 grams of black nightshade, 15 grams of moutan bark, 12 grams of Poria cocos, 15 grams of safflower, 15 grams of the capsule of weeping forsythia, 8 grams of Ligusticum wallichii, 20 grams of Snakegourd Fruit, Job's tears
15 grams of benevolence, 12 grams of the bighead atractylodes rhizome, 8 grams of cattail pollen.
3. the preparation method of medicine according to claim 1 or claim 2, it comprises the following steps：
（One）Get the raw materials ready
（1）Radix Codonopsis：Reed, section or segment are run through after clean silt, is dried；
（2）Asian puccoon：Clean, run through, cut into slices, dry；
（3）Motherwort：Impurity is picked, is cleaned, run through, segment is dried；
（4）Subprostrate sophora：Net impurity is picked, thickness stepping is soaked in water, pulls out, cut into slices after running through, dried；
（5）Rheum officinale：Net impurity is picked, size stepping, vexed profit to inside and outside humidity is uniform, cuts into slices or is cut into small pieces, dries；
（6）Oldenlandia diffusa：Crude drug is taken, impurity is removed, wash quickly is net, slightly dries in the air, segment is dried, and weeds out grey bits；
（7）Cassia twig：Slightly soaked with water, pulled out, it is vexed to moisten to saturating, section, dry, weed out bits；
（8）Radix Glycyrrhizae：Pick impurity, clean, be soaked in water to eighty per cant it is saturating when, pull out, run through section, dry；
（9）Phoenix-tail fern：The soil on surface is removed after adopting, is cleaned, dried；
（10）Excrementum pteropi：Net impurity is picked, grey bits are smashed or weed out；
（11）Fructus meliae toosendan：Impurity is picked, is cleaned, drying or is split into two halves at grating；
（12）The radix paeoniae rubrathe：Crude drug is taken, impurity is removed, size stepping is cleaned, run through, shave, is dried, and weeds out chip；
（13）Sculellaria barbata：Impurity is removed, is cleaned, slightly moistened, segment, be dried；
（14）Peach kernel：Duricrust impurity is removed, is put in boiling water pot and is boiled to crust microcreping, pulled out, in immersion cold water, kind of a skin is removed in stranding, is shone
It is dry, winnow with a dustpan net；
（15）Chinese mahonia leaf：Autumn harvests, and picks net impurity, dries；
（16）Black nightshade：Crude drug is taken, old stalk, impurity is removed, is cleaned, slightly moistened, segment, be dried；
（17）Moutan bark：Impurity is picked, core is removed, is cleaned, run through, cut into slices, dried；
（18）Poria cocos：Be soaked in water, clean pull out, it is vexed after, cut into slices, dry；
（19）Safflower：Net impurity is picked, cauline leaf, base of a fruit head is removed, is dried；
（20）The capsule of weeping forsythia：Net impurity is picked, stranding is opened, except discarding stalk；
（21）Ligusticum wallichii：Impurity is picked, separates large and small, be soaked in water, solarization is dried in the air, cut into slices after vexed profit, be dried；
（22）Snakegourd Fruit：Crude drug, removing impurity and carpopodium, clean, flattening, chopping or fritter are taken, is dried；
（23）Coix seed：Crude drug is taken, residual cot, impurity is removed；
（24）The bighead atractylodes rhizome：Net impurity is picked, is soaked in water, pulled out after bubble, run through, cut into slices, dried；
（25）Cattail pollen：Broken caking is rubbed, is sieved, remove impurity；
（Two）Prepare
（1）By the Radix Codonopsis of the weight, Asian puccoon, motherwort, subprostrate sophora, rheum officinale, oldenlandia diffusa, cassia twig, Radix Glycyrrhizae, phoenix-tail fern,
Excrementum pteropi, Fructus meliae toosendan, the radix paeoniae rubrathe, Sculellaria barbata, peach kernel, Chinese mahonia leaf, black nightshade, moutan bark, Poria cocos, safflower, the capsule of weeping forsythia, Ligusticum wallichii, melon
Beach wormwood, coix seed, the bighead atractylodes rhizome, cattail pollen are put in decocting container, are added water 8 times and are measured, and after immersion 100 minutes, are fried by intense fire to boil and are risen, then with text
Fire is decocted 20 minutes, filters to obtain first time decoction liquor, and first time decoction liquor is poured in container；
（2）The dregs of a decoction of filtration are added water 6 times and is measured, boiled by intense fire, then with being cooked by slow fire 20 minutes, filter to obtain second decoction liquor；
（3）Decoction liquor mixing and stirring twice is incited somebody to action, is divided into 3 doses and is taken.
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