CN103550513A - Traditional Chinese medicine for treating cholestatic hepatitis - Google Patents

Traditional Chinese medicine for treating cholestatic hepatitis Download PDF

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CN103550513A
CN103550513A CN201310504683.XA CN201310504683A CN103550513A CN 103550513 A CN103550513 A CN 103550513A CN 201310504683 A CN201310504683 A CN 201310504683A CN 103550513 A CN103550513 A CN 103550513A
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herba
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chinese medicine
cholestatic hepatitis
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CN103550513B (en
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陈英娣
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Wang Guanjun
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Abstract

The invention relates to a traditional Chinese medicine for treating cholestatic hepatitis. The traditional Chinese medicine for treating the cholestatic hepatitis is prepared from the following medicinal materials in parts by weight: 14 parts of piper cubeba, 12 parts of elsholtzia, 8 parts of Himalayan horsegentian herb, 10 parts of melilot, 14 parts of pleione saxicola, 14 parts of lacebark pine cone, 16 parts of bodinier caper, 8 parts of altingia chingii metc., 14 parts of auricled hedyotis herb, 13 parts of cantonese speranskia, 16 parts of tamarindus, 15 parts of coriaria sinica, 12 parts of buddleja asiatica, 14 parts of combretum leaf, 8 parts of hemiboea subcapitata, 10 parts of codonopsis convolvulacea and 12 parts of lowdaphne stringbush flower and leaf. A clinical experiment proves that the traditional Chinese medicine for treating the cholestatic hepatitis can be used for safely and effectively treating the cholestatic hepatitis.

Description

A kind of Chinese medicine for the treatment of cholestatic hepatitis
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine for the treatment of cholestatic hepatitis.
Background technology
Cholestatic hepatitis be because of many reasons cause hepatocyte and (or) bile capillary paracholia, cause partially or completely the retardance of property bile flow.Multiple be born in acute hepatitis morbidity several weeks after.Cholestatic hepatitis be because of many reasons cause hepatocyte and (or) bile capillary paracholia, causing partially or completely the retardance of property bile flow is the syndrome of feature, accounts for 2~8% of icterohepatitis.
For cholestatic hepatitis, still lack at present the effective medicine of generally recognized as safe.
The present Research of the related medical material of Chinese medicine of the present invention is as follows:
Fructus Litseae [source] this product is Lauraceae Litsea plant cubeb litsen tree Litsea cubeba (Lour.) Pers., with fruit, root and leaf.Gather during fruit maturation autumn, and root, leaf can be adopted the whole year, remove impurity, dry.[function cures mainly] warming spleen and stomach for dispelling cold, promoting the circulation of QI to relieve pain.Root: for cold syndrome of the stomach vomiting, coldness and pain in the epigastrium, colic of cold type stomachache, stagnancy of cold-damp, turbid urine.
Herba Moslae [source] is the wounded in the battle herb of labiate elsholtzia splendens.[function cures mainly] diaphoresis expelling summer-heat, row water wet dissipation, during stomach warming is adjusted.Control Xia Yue sense cold fluid-retention cold, have a headache and fever, aversion to cold is lossless, feeling of stuffiness in chest stomachache, vomiting and diarrhoea, edema, beriberi.
Herba Triostei himalayani [source] the Caprifoliaceae stem of a herb Fischer platymiscium punching stem of a herb sugarcane Triosteum himalayanum Wall.[T.fargesii Franch.], with whole herb with root, be used as medicine.Xia Qiu excavates, and cleans and dries.[function cures mainly] inducing diuresis to remove edema, promoting blood flow to regulate menstruation.For edema, dysuria, menoxenia.
Herba meliloti [source] pulse family melilot Herba Meliloti officinalis Melilotus officinalis (L.) Desr., with all herbal medicine.Adopt summer, cleans and dry.[function cures mainly] relieving spasm to stop pain.For asthma, bronchitis, intestinal colic; Wound is controlled in external, and lymph node swells and ache.
The beautiful phoenix flower of the beautiful phoenix flower plant of twoflower rattlesnake plantain [source] the orchid family Pluma Anseris domestica Habenaria dentata (Swartz) Schlecht. (Habenaria miersiana Champ.), is used as medicine with tuber.Autumn and winter excavate, and clean steaming, dry or using fresh herb.[function cures mainly] tonifying the lung kidney, diuresis.For lumbago due to renal deficiency, body is empty after being ill, impotence due to deficiency of the kidney, colicky, stomachache, pulmonary tuberculosis cough, orchitis, urinary tract infection.
The cone of the Strobilus Pini [source] Pinaceae pine genus plant lacebark pine (Periostracum Serpentis pine, Budgerigar loose) Pinus bungeana Zucc..[function cures mainly] eliminates the phlegm, and cough-relieving is relievingd asthma.Chronic tracheitis, asthma, cough with copious phlegm.
Cortex capparis Bodinieri radicis [source] Capparidaceae Chinese lime platymiscium Cortex capparis Bodinieri radicis, is used as medicine with Herb, root bark.Autumn and winter gather, and clean section, dry.[function cures mainly] relaxing muscles and tendons and activating QI and blood in the collateral, heat-clearing and toxic substances removing.Herb: for rheumatalgia, traumatic injury; Root bark: tonsillitis, toothache.
Ramulus et Folium Semiliquidambaris cathayensis [source] is Hamamelidaceae Altingia plant Ramulus et Folium Semiliquidambaris cathayensis Altingia chingii Metc, with root or branch, leaf is used as medicine.Can adopt the whole year, dries respectively standby.[function cures mainly] expelling wind and removing dampness, relaxing muscles and tendons to promote blood circulation.For rheumatic arthritis, rheumatoid arthritis, lumbar muscle strain, chronic lambago and skelalgia, hemiplegia, traumatic injury, bruise; External is controlled on cutter hemorrhage.
The herb of Auricled Hedyotis Herb [source] Rubiaceae plants of Hedyotis Auricled Hedyotis Herb Hedyotis auricularia L..Can adopt the whole year, cleans using fresh herb or dry.[function cures mainly] heat-clearing and toxic substances removing, removing heat from blood detumescence.For cold, fever, cough due to lung-heat, laryngalgia, acute conjunctivitis, enteritis, dysentery; Venom is controlled in external, traumatic injury, carbuncle pyogenic infections from tumour or sore, mastitis, eczema.
Herba speranskiae cantonensis [source] Euphorbiaceae Speranskia plant tumor fruit speranskia tuberculata Speranskia cantoniensis (Hance) Px et Hoffm., with all herbal medicine.Gather herb autumn, dry.[function cures mainly] dispels wind and removes dampness, promoting blood flow to regulate menstruation, pain relieving.For flu, cough due to consumptive disease, tuberculous lymphadenitis, rheumatic arthritis, sciatica, traumatic injury, menoxenia, leucorrhea.
Tamarind [source] pulse family tamarind platymiscium tamarind Tamarindus indica L., with fruit medicine.Adopt spring, removes seed, dries.[function cures mainly] clearing away summer-heat, promoting digestion and removing stagnation.For heatstroke, inappetence, infantile malnutrition, vomiting during pregnancy, constipation.
Coriaria sinica [source] Coriariaceae Coriaria plant Coriaria sinica Coriaria sinica Maxim., is used as medicine with root, leaf.Root is excavated winter, scrapes off crust, dries; Leaf is adopted summer, dries.[function cures mainly] expelling wind and removing dampness, analgesia, parasite killing.Root: for tuberculous lymphadenitis, traumatic injury, lyssodexis, rheumatic arthritis; Leaf: burn and scald is controlled in external, tinea capitis, eczema, sore swollen toxin.
Herba Gendarussae (Caulis et Folium Gendarussae vulgaris) [source] is wrapped up in hedge firewood platymiscium for Acanthaceae and is wrapped up in hedge firewood Gendarussa vulgaris Nees[Justicia gendarussa L.F.] with Herb, be used as medicine.Can adopt the whole year, cleans and dry or using fresh herb.[function cures mainly] reunion of fractured tendons and bones, reducing swelling and alleviating pain.For fracture, bruise, rheumatic arthritis.
The sub-Combretum alfredii of Folium Combreti Alferedii [source] Combretum Racemosum Combretum plant windmill Hance, is used as medicine with root, leaf.Autumn and winter adopt, and clean using fresh herb or dry in the shade.[function cures mainly] root: heat clearing away, function of gallbladder promoting.For icterohepatitis.Leaf: anthelmintic.For ascariasis, trichuriasis.The bright leaf of external is controlled burn and scald.
Herba Hemiboeae [source] Gesneriaceae Hemiboea plant Herba Hemiboeae Hemiboea subcapitara Clarke, with all herbal medicine.Adopt after autumn, clean and dry.[function cures mainly] removing toxic substances.For venom, furuncle.
The plant Radix Codonopsis Convolvulaceae Codonopsis convolvulacea Kurz. of Radix Codonopsis Convolvulaceae [source] campanulaceae Codonopsis, is used as medicine with root.Excavate autumn, cleans and dry.[function cures mainly] invigorating QI and blood, the lung moistening and production of body fluid promoting.For anemia, spontaneous perspiration, deficiency of lung-YIN cough, neurasthenia.
The alabastrum of Flos wikstroemiae chamaedaphnes (Flos et follium wikstroemiae chamaedaphnis) [source] thymelaeceae Flos Wikstroemiae Dolichanthae platymiscium Wikstroemia chamaedaphne (Bge.) Meisn. Wikstroemia chamaedaphne Meisn., leaf also can be used as medicine.Pick flowers early autumn flower bud and leaf, dry in the shade or dry.[function cures mainly] removing water retention by purgation, relieving constipation.For edema distension, phlegm retention is gathered, cough with dyspnea dyspnea with fullness of the chest, acute and chronic infectious hepatitis, schizophrenia, epilepsy.
Summary of the invention
The present invention aims to provide a kind of Chinese medicine for the treatment of cholestatic hepatitis, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective healing cholestatic hepatitis.
In order to achieve the above object, the present invention is by the following technical solutions:
A kind of Chinese medicine for the treatment of cholestatic hepatitis, it is characterized in that, by the medical material of following weight proportion, be prepared from: 14 parts of Fructus Litseae, 12 parts of Herba Moslaes, 8 parts of Herba Triostei himalayani, 10 parts of herba melilotis, 14 parts of twoflower rattlesnake plantains, 14 parts of the Strobilus Pinis, 16 parts of Cortex capparis Bodinieri radiciss, 8 parts of Ramulus et Folium Semiliquidambaris cathayensis, 14 parts of Auricled Hedyotis Herbs, 13 parts of Herba speranskiae cantonensiss, 16 parts of tamarinds, 15 parts of Coriaria sinicas, 12 parts of Herba Gendarussae (Caulis et Folium Gendarussae vulgaris)s, 14 parts of Folium Combreti Alferediis, 8 parts of Herba Hemiboeaes, 10 parts of Radix Codonopsis Convolvulaceaes, 12 parts of Flos wikstroemiae chamaedaphnes (Flos et follium wikstroemiae chamaedaphnis)s.
Below in conjunction with clinical experiment data declaration beneficial effect of the present invention:
1, physical data
The out-patient that inventor collects 80 routine cholestatic hepatitiss between year December of JIUYUE-2012 in 2009 altogether, age 24-60 year, course of disease 1-7.Be divided at random: treatment group 55 examples, blank group 25 examples.The data there was no significant differences such as two groups of ages, the state of an illness, have comparability.
2, test method
The capsule that the oral the present invention of 2.1 treatment group makes according to specific embodiment 1, sooner or later respectively once.7 days courses for the treatment of.
2.2 blank group oral placebo capsules, sooner or later respectively once.7 days courses for the treatment of.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
Recovery from illness: clinical symptoms all disappears, and test chamber inspection is normal.Take a turn for the better: clinical symptom relief, the state of an illness is controlled, and lab testing improves or is normal.Invalid: clinical symptoms is without being clearly better or increasing the weight of.
3.2 treatment statistical results are in Table 1.
Table 1 liang group curative effect comparison
Group n Recovery from illness Take a turn for the better Invalid Untoward reaction example Total effective rate (%)
Treatment group 55 11(20%) 32(58.2%) 12(21.8%) 0 78.2%
Blank group 25 0 7(28%) 18(72%) 0 28%
Visible, the medicine that the present invention makes can safe and effectively be controlled cholestatic hepatitis.
The specific embodiment
In order to understand better and to implement the present invention, below in conjunction with specific embodiment, further illustrate the present invention.
Specific embodiment 1
Take: 14 grams of Fructus Litseae, 12 grams of Herba Moslaes, 8 grams of Herba Triostei himalayani, 10 grams of herba melilotis, 14 grams of twoflower rattlesnake plantains, 14 grams of the Strobilus Pinis, 16 grams of Cortex capparis Bodinieri radiciss, 8 grams of Ramulus et Folium Semiliquidambaris cathayensis, 14 grams of Auricled Hedyotis Herbs, 13 grams of Herba speranskiae cantonensiss, 16 grams of tamarinds, 15 grams of Coriaria sinicas, 12 grams of Herba Gendarussae (Caulis et Folium Gendarussae vulgaris)s, 14 grams of Folium Combreti Alferediis, 8 grams of Herba Hemiboeaes, 10 grams of Radix Codonopsis Convolvulaceaes, 12 grams of Flos wikstroemiae chamaedaphnes (Flos et follium wikstroemiae chamaedaphnis)s, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, incapsulate shell, must meet the capsule of 1 day consumption of normal adult.
Be used for the treatment of cholestatic hepatitis.Oral, every bu is taken for twice sooner or later.
Specific embodiment 2
Take: 14 grams of Fructus Litseae, 12 grams of Herba Moslaes, 8 grams of Herba Triostei himalayani, 10 grams of herba melilotis, 14 grams of twoflower rattlesnake plantains, 14 grams of the Strobilus Pinis, 16 grams of Cortex capparis Bodinieri radiciss, 8 grams of Ramulus et Folium Semiliquidambaris cathayensis, 14 grams of Auricled Hedyotis Herbs, 13 grams of Herba speranskiae cantonensiss, 16 grams of tamarinds, 15 grams of Coriaria sinicas, 12 grams of Herba Gendarussae (Caulis et Folium Gendarussae vulgaris)s, 14 grams of Folium Combreti Alferediis, 8 grams of Herba Hemiboeaes, 10 grams of Radix Codonopsis Convolvulaceaes, 12 grams of Flos wikstroemiae chamaedaphnes (Flos et follium wikstroemiae chamaedaphnis)s, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, pulverize, must meet the powder of 1 day consumption of normal adult.
Be used for the treatment of cholestatic hepatitis.Oral, every bu is taken for twice sooner or later.
Specific embodiment 3
Take: 14 grams of Fructus Litseae, 12 grams of Herba Moslaes, 8 grams of Herba Triostei himalayani, 10 grams of herba melilotis, 14 grams of twoflower rattlesnake plantains, 14 grams of the Strobilus Pinis, 16 grams of Cortex capparis Bodinieri radiciss, 8 grams of Ramulus et Folium Semiliquidambaris cathayensis, 14 grams of Auricled Hedyotis Herbs, 13 grams of Herba speranskiae cantonensiss, 16 grams of tamarinds, 15 grams of Coriaria sinicas, 12 grams of Herba Gendarussae (Caulis et Folium Gendarussae vulgaris)s, 14 grams of Folium Combreti Alferediis, 8 grams of Herba Hemiboeaes, 10 grams of Radix Codonopsis Convolvulaceaes, 12 grams of Flos wikstroemiae chamaedaphnes (Flos et follium wikstroemiae chamaedaphnis)s, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, then add appropriate dextrin and correctives, and according to this area common process, to granulate, packing, can make the granule that meets 1 day consumption of normal adult.
Be used for the treatment of cholestatic hepatitis.Oral, every bu is taken for twice sooner or later.

Claims (1)

1. a Chinese medicine for the treatment of cholestatic hepatitis, it is characterized in that, by the medical material of following weight proportion, be prepared from: 14 parts of Fructus Litseae, 12 parts of Herba Moslaes, 8 parts of Herba Triostei himalayani, 10 parts of herba melilotis, 14 parts of twoflower rattlesnake plantains, 14 parts of the Strobilus Pinis, 16 parts of Cortex capparis Bodinieri radiciss, 8 parts of Ramulus et Folium Semiliquidambaris cathayensis, 14 parts of Auricled Hedyotis Herbs, 13 parts of Herba speranskiae cantonensiss, 16 parts of tamarinds, 15 parts of Coriaria sinicas, 12 parts of Herba Gendarussae (Caulis et Folium Gendarussae vulgaris)s, 14 parts of Folium Combreti Alferediis, 8 parts of Herba Hemiboeaes, 10 parts of Radix Codonopsis Convolvulaceaes, 12 parts of Flos wikstroemiae chamaedaphnes (Flos et follium wikstroemiae chamaedaphnis)s.
CN201310504683.XA 2013-10-23 2013-10-23 A kind of Chinese medicine treating cholestatic hepatitis Expired - Fee Related CN103550513B (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104940838A (en) * 2015-07-16 2015-09-30 王艳娣 Traditional Chinese medicine composition for treating cholestatic hepatitis
CN105597026A (en) * 2016-03-03 2016-05-25 青岛市黄岛区中医医院 Traditional Chinese medicine decoction for treating cholestatic hepatitis
CN105853806A (en) * 2016-05-27 2016-08-17 王德欣 Traditional Chinese medicine for treating cholestatic hepatitis and preparation method thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1539490A (en) * 2003-11-04 2004-10-27 向忠友 Chinese traditional medicine for curing cholestatic hepatitis and preparing method
CN1899572A (en) * 2006-07-21 2007-01-24 贺长青 Chinese medicine for treating hepatitis B and its preparing method
CN101152467A (en) * 2007-09-28 2008-04-02 天津飞鹰制药有限公司 Traditional Chinese medicine preparation for treating urgent and chronic hepatitis

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1539490A (en) * 2003-11-04 2004-10-27 向忠友 Chinese traditional medicine for curing cholestatic hepatitis and preparing method
CN1899572A (en) * 2006-07-21 2007-01-24 贺长青 Chinese medicine for treating hepatitis B and its preparing method
CN101152467A (en) * 2007-09-28 2008-04-02 天津飞鹰制药有限公司 Traditional Chinese medicine preparation for treating urgent and chronic hepatitis

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104940838A (en) * 2015-07-16 2015-09-30 王艳娣 Traditional Chinese medicine composition for treating cholestatic hepatitis
CN105597026A (en) * 2016-03-03 2016-05-25 青岛市黄岛区中医医院 Traditional Chinese medicine decoction for treating cholestatic hepatitis
CN105853806A (en) * 2016-05-27 2016-08-17 王德欣 Traditional Chinese medicine for treating cholestatic hepatitis and preparation method thereof

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