CN103316132A - Compound medicine for preventing and treating fish liver-gall syndrome - Google Patents
Compound medicine for preventing and treating fish liver-gall syndrome Download PDFInfo
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- CN103316132A CN103316132A CN2013102378462A CN201310237846A CN103316132A CN 103316132 A CN103316132 A CN 103316132A CN 2013102378462 A CN2013102378462 A CN 2013102378462A CN 201310237846 A CN201310237846 A CN 201310237846A CN 103316132 A CN103316132 A CN 103316132A
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Abstract
The invention discloses a compound medicine for preventing and treating fish liver-gall syndrome. The compound medicine is characterized by being composed of the following raw material medicines in parts by weight: 20 parts of andrographis paniculata, 12.5 parts of cape jasmine, 15 parts of oriental wormwood, 15 parts of rheum officinale, 10 parts of golden cypress, 1 part of berberine, 7.5 parts of liquorice, 4 parts of Vitamin C, 0.5 part of Vitamin E, 0.75 part of choline chloride, 4 parts of glucurolactone, and 10 parts of bentonite, wherein the components aforementioned are uniformly mixed, crushed by an ultrafine crusher and with a crushing finesses of 8-20 microns, mixed, and uniformly stirred.
Description
Technical field
The invention belongs to aquaculture modern agriculture field, in particular to the preparation method of control liver and gallbladder syndrome medicine, particularly a kind of compound medicine and preparation method of preventing and treating liver and gall syndrome of fish.
Background technology
In recent years, along with popularizing of Fish intensive culture technology, its cultured output improves constantly, but the meanwhile generation of Fish diseases related is also day by day serious.The fish disease take hepatobiliary disease as principal character (being commonly called as " liver and gall syndrome of fish ") wherein, it is more and more one of fish diseases of day by day prolonging of wide (generally popular in all parts of the country) and epidemic season of sickness rate more and more high (severe patient can reach 100%) during nowadays fish culture is produced, influence surface, such as inappropriate medication, its mortality rate can reach 50%～60%, even can reach 60%～90%, seriously affected the economic benefit of aquaculture.Chinese scholars has been carried out some researchs to this disease, but these research reports concentrate on the aspects such as dissection observation of symptoms to liver and gall syndrome of fish, possible etiological analysis and prophylactico-therapeutic measures mostly, and the appropriate adoption Chinese medicine formula removes to study the report to the prevention effect of liver and gall syndrome of fish, and is still rare so far.Therefore, how to adopt Chinese medicine formula that the Fish liver and gall diseases is carried out therapeutic test, checking this compound preparation is the technical problem that this area needs to be resolved hurrily to the effectiveness of liver and gall syndrome of fish control.
Summary of the invention
The invention provides a kind of compound medicine and preparation method of preventing and treating liver and gall syndrome of fish.Compound medicine of the present invention is by weight by the commercially available Herba Andrographis, Fructus Gardeniae, Herba Artemisiae Scopariae, Radix Et Rhizoma Rhei, Cortex Phellodendri, berberine, the Radix Glycyrrhizae that meet " Chinese veterinary pharmacopoeia " version standard in 2005; VC, VE, choline chloride, glucuronolatone, bentonite consist of.Compound medicine of the present invention can be effective to the control of liver and gall syndrome of fish, is particularly useful for the control of the liver and gallbladder syndrome such as liver and gall pathological changes that Fish cause by bacterial disease and nutritional fatty liver, liver and gall enlargement, flower liver.Mix bait by aquatic animal for oral administration, the conditioning liver and gall make the liver and gall of pathological changes recover normal.Have evident in efficacy, the characteristics that have no side effect.This pharmaceutical composition adopts superfine communication technique preparation, and powder diameter is little, is evenly distributed, the quality homogeneous, can reduce drug use dosage, saves herb resource, reduces cost.
To achieve these goals, technical scheme of the present invention is:
A kind of compound medicine and preparation method of preventing and treating liver and gall syndrome of fish takes by weighing following crude drug by weight: 20 parts of Herba Andrographis, 12.5 parts of Fructus Gardeniaes, 15 parts of Herba Artemisiae Scopariaes, 15 parts of Radix Et Rhizoma Rhei, 10 parts of Cortex Phellodendris, 1 part of berberine, 7.5 parts in Radix Glycyrrhizae; Said components is evenly mixed, use the YSC-715 type Chinese herbal medicine super micron mill of the Yanshan Mountain, Beijing positive moral plant equipment company limited production to pulverize, smashing fineness can reach 8～20 μ m; Take by weighing by weight 4 parts of vitamin Cs, 0.5 part of vitamin E, 0.75 part of choline chloride, 4 parts of glucuronolatone, 10 parts of bentonite; Their are mixed with micro-powder of Chinese herbs of pulverizing, stir, the herbal mixture 100g of preparation is admixed in the 40kg feedstuff, then by the 5% daily ration, feeding quantity Ctenopharyngodon idellus of throwing something and feeding, each bait throwing in of every day at upper and lower noon 1 time is used in conjunction 15d.
The specific embodiment
Below will be described in detail the preferred embodiments of the present invention; Should be appreciated that preferred embodiment only for the present invention is described, rather than in order to limit protection scope of the present invention.
Embodiment 1
This test is raised peasant household's aquaculture pond scattered in Nanchang County, Nanchang City, Jiangxi Province and is carried out Ctenopharyngodon idellus, long (10 ± 0.2) cm of body; The visible pond waters of field observation surface a lot of fish that dies of illness of wafing, on-the-spot touch and the mode such as perusal detects the morbidity fish or dying fish is found Ctenopharyngodon idellus external symptom and the random inspection 10 tail fish internal symptons of dissecting all to show significantly ill (liver and gallbladder syndrome) feature with hands.
Take by weighing by weight following crude drug: 20 parts of Herba Andrographis, 12.5 parts of Fructus Gardeniaes, 15 parts of Herba Artemisiae Scopariaes, 15 parts of Radix Et Rhizoma Rhei, 10 parts of Cortex Phellodendris, 1 part of berberine, 7.5 parts in Radix Glycyrrhizae; Said components is evenly mixed, use the YSC-715 type Chinese herbal medicine super micron mill of the Yanshan Mountain, Beijing positive moral plant equipment company limited production to pulverize, smashing fineness can reach 8～20 μ m; Take by weighing by weight 4 parts of vitamin Cs, 0.5 part of vitamin E, 0.75 part of choline chloride, 4 parts of glucuronolatone, 10 parts of bentonite; They are mixed with the micro-powder of Chinese herbs of pulverizing, stir.
The herbal mixture 100g of above-mentioned preparation is admixed in the 40kg feedstuff, and then by the 5% daily ration, feeding quantity Ctenopharyngodon idellus of throwing something and feeding, each bait throwing in of every day at upper and lower noon 1 time is used in conjunction 15d.
The visible pond waters of field observation surface a lot of fish that dies of illness of wafing, according to fisherman's introduction, every day dead fish quantity all more than 100 tails, the sick fish of perusal, find fish body blackout, become thin, the tail fin blackout, gill filament edema is turned white or mashed silk, mostly peels off solely to swim in the water surface, bank or place, lower air port.Not material feeding during bait throwing in.Cut abdominal part open, liver is khaki, and color is thin out or pale, is graniphyric.Pinch frangiblely with hands, put into water and easily scatter.The gallbladder enlargement, the attenuation of gallbladder wall, it is blackish green that bile is, nothing food or few food in the inflammatory bowel, intestinal, and be full of yellow mucus.
After using 15d continuously, the fish quantity of finding to die of illness obviously reduces, and can see 1～2 tail every day at most, and the survival rate of Ctenopharyngodon idellus obviously improves.Throw something and feed after the compound medicine, Ctenopharyngodon idellus is carried out anatomic observation, find that body colour, the epidermal mucus of fish recovered normally, reaction is quick, and dorsal fin and tail fin color restoration are normal; Gill section mucus obviously reduces, and gill section congestion, congested phenomenon disappear; Liver form, color and luster, quality and gallbladder size and bile color restoration are normal, and enteritis disappears.
The above, it only is preferred embodiment of the present invention, be not that the present invention is done any pro forma restriction, although the present invention with preferred embodiment openly as above, yet, be not to limit the present invention, any those skilled in the art, within not breaking away from the technical solution of the present invention scope, certainly can utilize the technology contents of announcement to make a little change or modification, become the equivalent embodiment of equivalent variations, be the content that does not break away from technical solution of the present invention in every case, any simple modification that foundation technical spirit of the present invention is done above embodiment, equivalent variations and modification all belong in the scope of technical solution of the present invention.
Claims (2)
1. compound medicine of preventing and treating liver and gall syndrome of fish, it is characterized in that, become by following raw material medicaments in part by weight array: 20 parts of Herba Andrographis, 12.5 parts of Fructus Gardeniaes, 15 parts of Herba Artemisiae Scopariaes, 15 parts of Radix Et Rhizoma Rhei, 10 parts of Cortex Phellodendris, 1 part of berberine, 7.5 parts in Radix Glycyrrhizae, 4 parts of vitamin Cs, 0.5 part of vitamin E, 0.75 part of choline chloride, 4 parts of glucuronolatone, 10 parts of bentonite, said components is evenly mixed, use super micron mill to pulverize, smashing fineness 8～20 μ m mix, and stir.
2. the application method of the compound medicine of the control liver and gall syndrome of fish shown in claim 1 is admixed the herbal mixture 100g of preparation in the 40kg feedstuff, and then by the 5% daily ration, feeding quantity Ctenopharyngodon idellus of throwing something and feeding, each bait throwing in of every day at upper and lower noon 1 time is used in conjunction 15d.
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Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103610805A (en) * | 2013-11-13 | 2014-03-05 | 赵林斌 | Traditional Chinese medicinal composition for preventing and treating hepatobiliary syndrome of fish |
| CN104431368A (en) * | 2014-12-15 | 2015-03-25 | 中国水产科学研究院长江水产研究所 | Compound feed additive for promoting healthy growth of fishes and preparation method |
| CN104887748A (en) * | 2015-06-01 | 2015-09-09 | 扬中牧乐药业有限公司 | Compound preparation for preventing and treating liver and gall syndromes of aquatic animals |
| CN107661460A (en) * | 2017-11-27 | 2018-02-06 | 衡阳市日升娃娃鱼养殖基地 | Prevent and treat Chinese medicine extract of giant salamander liver and gall syndrome and preparation method thereof |
| CN108783112A (en) * | 2018-07-04 | 2018-11-13 | 珠海海龙生物科技有限公司 | Repair functional additive and the functional feed and its preparation method and application of jewfish liver cell enlargement |
| CN109349457A (en) * | 2018-10-26 | 2019-02-19 | 镇江市绿色农业科技有限公司 | A kind of hilsa herring liver-protection health-care product |
| CN112402493A (en) * | 2020-11-26 | 2021-02-26 | 湖南佳锐思丹维生物科技有限公司 | Preparation and application method of liver-protecting and growth-promoting compound Chinese herbal medicine preparation for micropterus salmoides |
| CN112544796A (en) * | 2020-12-23 | 2021-03-26 | 天津现代天骄水产饲料股份有限公司 | Compound feed for preventing and treating liver and gall syndrome of grass carps and preparation method thereof |
| CN115869362B (en) * | 2022-12-13 | 2023-09-15 | 山西农业大学 | Extraction process of total flavonoids and total physalin from calyx seu fructus physalis |
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| CN1706442A (en) * | 2005-05-30 | 2005-12-14 | 许建文 | Prepn process of medicine for treating icteric diseases and oral liquid containing the medicine |
| CN101002849A (en) * | 2007-01-30 | 2007-07-25 | 中国人民解放军第三○二医院 | Traditional Chinese medicine extractive or tablet for treating hepatitis, and its preparing method |
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Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103610805A (en) * | 2013-11-13 | 2014-03-05 | 赵林斌 | Traditional Chinese medicinal composition for preventing and treating hepatobiliary syndrome of fish |
| CN104431368A (en) * | 2014-12-15 | 2015-03-25 | 中国水产科学研究院长江水产研究所 | Compound feed additive for promoting healthy growth of fishes and preparation method |
| CN104887748A (en) * | 2015-06-01 | 2015-09-09 | 扬中牧乐药业有限公司 | Compound preparation for preventing and treating liver and gall syndromes of aquatic animals |
| CN107661460A (en) * | 2017-11-27 | 2018-02-06 | 衡阳市日升娃娃鱼养殖基地 | Prevent and treat Chinese medicine extract of giant salamander liver and gall syndrome and preparation method thereof |
| CN108783112A (en) * | 2018-07-04 | 2018-11-13 | 珠海海龙生物科技有限公司 | Repair functional additive and the functional feed and its preparation method and application of jewfish liver cell enlargement |
| CN109349457A (en) * | 2018-10-26 | 2019-02-19 | 镇江市绿色农业科技有限公司 | A kind of hilsa herring liver-protection health-care product |
| CN112402493A (en) * | 2020-11-26 | 2021-02-26 | 湖南佳锐思丹维生物科技有限公司 | Preparation and application method of liver-protecting and growth-promoting compound Chinese herbal medicine preparation for micropterus salmoides |
| CN112544796A (en) * | 2020-12-23 | 2021-03-26 | 天津现代天骄水产饲料股份有限公司 | Compound feed for preventing and treating liver and gall syndrome of grass carps and preparation method thereof |
| CN115869362B (en) * | 2022-12-13 | 2023-09-15 | 山西农业大学 | Extraction process of total flavonoids and total physalin from calyx seu fructus physalis |
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| CN103316132B (en) | 2015-10-21 |
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