CN103316132B - A kind of compound medicine preventing and treating liver and gall syndrome of fish - Google Patents
A kind of compound medicine preventing and treating liver and gall syndrome of fish Download PDFInfo
- Publication number
- CN103316132B CN103316132B CN201310237846.2A CN201310237846A CN103316132B CN 103316132 B CN103316132 B CN 103316132B CN 201310237846 A CN201310237846 A CN 201310237846A CN 103316132 B CN103316132 B CN 103316132B
- Authority
- CN
- China
- Prior art keywords
- parts
- fish
- compound medicine
- liver
- vitamin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Abstract
A kind of compound medicine preventing and treating liver and gall syndrome of fish, it is characterized in that, become by following raw material medicaments in part by weight array: Herba Andrographis 20 parts, Fructus Gardeniae 12.5 parts, Herba Artemisiae Scopariae 15 parts, Radix Et Rhizoma Rhei 15 parts, Cortex Phellodendri 10 parts, berberine 1 part, 7.5 parts, Radix Glycyrrhizae, vitamin C 4 parts, vitamin E 0.5 part, choline chloride 0.75 part, glucuronolatone 4 parts, bentonite 10 parts, by said components Homogeneous phase mixing, super micron mill is used to pulverize, smashing fineness reaches 8 ~ 20 μm, and mixing, stirs.
Description
Technical field
The invention belongs to aquaculture modern agriculture field, in particular to the preparation method of control liver and gallbladder syndrome medicine, particularly a kind of compound medicine and preparation method of preventing and treating liver and gall syndrome of fish.
Background technology
In recent years, along with popularizing of Fish intensive culture technology, its cultured output improves constantly, but the meanwhile generation of Fish diseases related is also day by day serious.It is wherein the fish disease (being commonly called as " liver and gall syndrome of fish ") of principal character with hepatobiliary disease, it is one of fish diseases that in nowadays fish culture production, sickness rate more and more high (severe patient can reach 100%), influence surface more and more wider (generally popular in all parts of the country) and epidemic season extend day by day, as inappropriate medication, its mortality rate can reach 50% ~ 60%, even can reach 60% ~ 90%, seriously have impact on the economic benefit of aquaculture.Chinese scholars has carried out some researchs to this disease, but these research reports concentrate on the aspects such as the dissection observation of symptoms to liver and gall syndrome of fish, possible etiological analysis and prophylactico-therapeutic measures mostly, and really adopt Chinese medicine formula to remove to study the report to the prevention effect of liver and gall syndrome of fish, still rare so far.Therefore, how to adopt Chinese medicine formula to carry out therapeutic test to Fish liver and gall diseases, check this compound preparation to be this area technical problem urgently to be resolved hurrily to the effectiveness that liver and gall syndrome of fish is prevented and treated.
Summary of the invention
The invention provides a kind of compound medicine and preparation method of preventing and treating liver and gall syndrome of fish.Compound medicine of the present invention is by weight by meeting the commercially available Herba Andrographis of " Chinese veterinary pharmacopoeia " version standard in 2005, Fructus Gardeniae, Herba Artemisiae Scopariae, Radix Et Rhizoma Rhei, Cortex Phellodendri, berberine, Radix Glycyrrhizae; VC, VE, choline chloride, glucuronolatone, bentonite are formed.Compound medicine of the present invention can be effective to the control of liver and gall syndrome of fish, is particularly useful for the control of the liver and gallbladder syndrome such as liver and gall pathological changes that Fish cause by bacterial disease and nutritional fatty liver, liver and gall enlargement, flower liver.Mix bait by aquatic animal to take orally, conditioning liver and gall, make the liver and gall of pathological changes recover normal.Have evident in efficacy, the feature had no side effect.This pharmaceutical composition adopts superfine communication technique preparation, and powder diameter is little, is evenly distributed, quality is homogeneous, can reduce drug use dosage, saves herb resource, reduces costs.
To achieve these goals, technical scheme of the present invention is:
Prevent and treat compound medicine and the preparation method of liver and gall syndrome of fish, take following crude drug by weight: Herba Andrographis 20 parts, Fructus Gardeniae 12.5 parts, Herba Artemisiae Scopariae 15 parts, Radix Et Rhizoma Rhei 15 parts, Cortex Phellodendri 10 parts, berberine 1 part, 7.5 parts, Radix Glycyrrhizae; By said components Homogeneous phase mixing, the broken machine of YSC-715 type Chinese herbal medicine ultra-fine powder using the Yanshan Mountain, Beijing Zheng De plant equipment company limited to produce is pulverized, and smashing fineness can reach 8 ~ 20 μm; Take vitamin C 4 parts, vitamin E 0.5 part, choline chloride 0.75 part, glucuronolatone 4 parts, bentonite 10 parts by weight; They mixed with the micro-powder of Chinese herbs pulverized, stir, admix in 40kg feedstuff by the herbal mixture 100g of preparation, then to throw something and feed Ctenopharyngodon idellus by 5% daily ration, feeding quantity, every day at upper and lower noon each bait throwing in 1 time, is used in conjunction 15d.
Detailed description of the invention
Below will be described in detail the preferred embodiments of the present invention; Should be appreciated that preferred embodiment only in order to the present invention is described, instead of in order to limit the scope of the invention.
Embodiment 1
This test is raised peasant household's aquaculture pond scattered in Nanchang City, Jiangxi Province Nanchang County and is carried out, Ctenopharyngodon idellus, long (10 ± 0.2) cm of body; The surperficial a lot of fish that dies of illness of wafing of the visible pond waters of field observation, the modes such as scene hands touch and perusal detect morbidity fish or dying fish finds Ctenopharyngodon idellus external symptom and random dissection inspection 10 tail fish internal sympton, all show significantly ill (liver and gallbladder syndrome) feature.
Take following crude drug by weight: Herba Andrographis 20 parts, Fructus Gardeniae 12.5 parts, Herba Artemisiae Scopariae 15 parts, Radix Et Rhizoma Rhei 15 parts, Cortex Phellodendri 10 parts, berberine 1 part, 7.5 parts, Radix Glycyrrhizae; By said components Homogeneous phase mixing, the broken machine of YSC-715 type Chinese herbal medicine ultra-fine powder using the Yanshan Mountain, Beijing Zheng De plant equipment company limited to produce is pulverized, and smashing fineness can reach 8 ~ 20 μm; Take vitamin C 4 parts, vitamin E 0.5 part, choline chloride 0.75 part, glucuronolatone 4 parts, bentonite 10 parts by weight; They are mixed with the micro-powder of Chinese herbs pulverized, stirs.
Admix in 40kg feedstuff by the herbal mixture 100g of above-mentioned preparation, then to throw something and feed Ctenopharyngodon idellus by 5% daily ration, feeding quantity, every day at upper and lower noon each bait throwing in 1 time, is used in conjunction 15d.
The surperficial a lot of fish that dies of illness of wafing of the visible pond waters of field observation, according to fisherman's introduction, every day, dead fish quantity was all more than 100 tails, the sick fish of perusal, find fish body blackout, become thin, tail fin turns black, gill filament edema, turns white or rotten silk, mostly peels off and solely swims in the water surface, bank or lower air port place.Not material feeding during bait throwing in.Cut abdominal part open, liver is khaki, and color is thin out or pale, in graniphyric.Pinch with hands frangible, put into water and easily scatter.Gollbladder dilation, gallbladder wall is thinning, and bile is blackish green, inflammatory bowel, without food or few food in intestinal, and is full of yellow mucus.
After continuous use 15d, find that fish quantity of dying of illness obviously reduces, every day can see 1 ~ 2 tail at most, and the survival rate of Ctenopharyngodon idellus significantly improves.Throw something and feed after compound medicine, carry out anatomic observation to Ctenopharyngodon idellus, body colour, the epidermal mucus of discovery fish have recovered normal, and reaction is quick, and dorsal fin and tail fin color recover normal; Gill portion mucus obviously reduces, and gill portion congestion, congested phenomenon disappear; Liver morphology, color and luster, quality and gallbladder volume and bile color recover normal, and enteritis disappears.
The above, it is only preferred embodiment of the present invention, not any pro forma restriction is done to the present invention, although the present invention with preferred embodiment openly as above, but, and be not used to limit the present invention, any those skilled in the art, do not departing within the scope of technical solution of the present invention, certainly the technology contents of announcement can be utilized to make a little change or modification, become the Equivalent embodiments of equivalent variations, in every case be the content not departing from technical solution of the present invention, according to any simple modification that technical spirit of the present invention is done above embodiment, equivalent variations and modification, all belong in the scope of technical solution of the present invention.
Claims (1)
1. prevent and treat the compound medicine of liver and gall syndrome of fish for one kind, it is characterized in that, become by following raw material medicaments in part by weight array: Herba Andrographis 20 parts, Fructus Gardeniae 12.5 parts, Herba Artemisiae Scopariae 15 parts, Radix Et Rhizoma Rhei 15 parts, Cortex Phellodendri 10 parts, berberine 1 part, 7.5 parts, Radix Glycyrrhizae, vitamin C 4 parts, vitamin E 0.5 part, choline chloride 0.75 part, glucuronolatone 4 parts, bentonite 10 parts, by said components Homogeneous phase mixing, super micron mill is used to pulverize, smashing fineness 8 ~ 20 μm, mixing, stir, the compound medicine 100g of preparation is admixed in 40kg feedstuff, then to throw something and feed Ctenopharyngodon idellus by 5% daily ration, feeding quantity, every the sky, each bait throwing in 1 time in afternoon, be used in conjunction 15d.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310237846.2A CN103316132B (en) | 2013-06-03 | 2013-06-03 | A kind of compound medicine preventing and treating liver and gall syndrome of fish |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310237846.2A CN103316132B (en) | 2013-06-03 | 2013-06-03 | A kind of compound medicine preventing and treating liver and gall syndrome of fish |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103316132A CN103316132A (en) | 2013-09-25 |
| CN103316132B true CN103316132B (en) | 2015-10-21 |
Family
ID=49185365
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310237846.2A Expired - Fee Related CN103316132B (en) | 2013-06-03 | 2013-06-03 | A kind of compound medicine preventing and treating liver and gall syndrome of fish |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103316132B (en) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103610805A (en) * | 2013-11-13 | 2014-03-05 | 赵林斌 | Traditional Chinese medicinal composition for preventing and treating hepatobiliary syndrome of fish |
| CN104431368A (en) * | 2014-12-15 | 2015-03-25 | 中国水产科学研究院长江水产研究所 | Compound feed additive for promoting healthy growth of fishes and preparation method |
| CN104887748A (en) * | 2015-06-01 | 2015-09-09 | 扬中牧乐药业有限公司 | Compound preparation for preventing and treating liver and gall syndromes of aquatic animals |
| CN107661460A (en) * | 2017-11-27 | 2018-02-06 | 衡阳市日升娃娃鱼养殖基地 | Prevent and treat Chinese medicine extract of giant salamander liver and gall syndrome and preparation method thereof |
| CN108783112A (en) * | 2018-07-04 | 2018-11-13 | 珠海海龙生物科技有限公司 | Repair functional additive and the functional feed and its preparation method and application of jewfish liver cell enlargement |
| CN109349457A (en) * | 2018-10-26 | 2019-02-19 | 镇江市绿色农业科技有限公司 | A kind of hilsa herring liver-protection health-care product |
| CN112402493A (en) * | 2020-11-26 | 2021-02-26 | 湖南佳锐思丹维生物科技有限公司 | Preparation and application method of liver-protecting and growth-promoting compound Chinese herbal medicine preparation for micropterus salmoides |
| CN112544796A (en) * | 2020-12-23 | 2021-03-26 | 天津现代天骄水产饲料股份有限公司 | Compound feed for preventing and treating liver and gall syndrome of grass carps and preparation method thereof |
| CN115869362B (en) * | 2022-12-13 | 2023-09-15 | 山西农业大学 | Extraction process of total flavonoids and total physalin from calyx seu fructus physalis |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1706442A (en) * | 2005-05-30 | 2005-12-14 | 许建文 | Prepn process of medicine for treating icteric diseases and oral liquid containing the medicine |
| CN101002849A (en) * | 2007-01-30 | 2007-07-25 | 中国人民解放军第三○二医院 | Traditional Chinese medicine extractive or tablet for treating hepatitis, and its preparing method |
| CN101590140A (en) * | 2008-05-30 | 2009-12-02 | 北京大北农动物保健科技有限责任公司 | A kind of compound medicament composition of preventing and treating liver and gall syndrome of fish and preparation method thereof |
| WO2012094832A1 (en) * | 2011-01-14 | 2012-07-19 | 广东药学院 | Compound chinese medicine extract used for preventing and treating arteriosclerosis and preparation method thereof |
| CN102697936A (en) * | 2012-06-28 | 2012-10-03 | 天津生机集团股份有限公司 | Chinese medicinal oral liquid for treating grass carp hemorrhage, and preparation method thereof |
-
2013
- 2013-06-03 CN CN201310237846.2A patent/CN103316132B/en not_active Expired - Fee Related
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1706442A (en) * | 2005-05-30 | 2005-12-14 | 许建文 | Prepn process of medicine for treating icteric diseases and oral liquid containing the medicine |
| CN101002849A (en) * | 2007-01-30 | 2007-07-25 | 中国人民解放军第三○二医院 | Traditional Chinese medicine extractive or tablet for treating hepatitis, and its preparing method |
| CN101590140A (en) * | 2008-05-30 | 2009-12-02 | 北京大北农动物保健科技有限责任公司 | A kind of compound medicament composition of preventing and treating liver and gall syndrome of fish and preparation method thereof |
| WO2012094832A1 (en) * | 2011-01-14 | 2012-07-19 | 广东药学院 | Compound chinese medicine extract used for preventing and treating arteriosclerosis and preparation method thereof |
| CN102697936A (en) * | 2012-06-28 | 2012-10-03 | 天津生机集团股份有限公司 | Chinese medicinal oral liquid for treating grass carp hemorrhage, and preparation method thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN103316132A (en) | 2013-09-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103316132B (en) | A kind of compound medicine preventing and treating liver and gall syndrome of fish | |
| Pu et al. | Research progress in the application of Chinese herbal medicines in aquaculture: a review | |
| CN101579043B (en) | Chinese medicinal herb additive for promoting the growth of piglet and application thereof | |
| CN102319309B (en) | Traditional Chinese medicine preparation for treating chicken coccidiosis | |
| CN103125756A (en) | Traditional Chinese medicine feed additive for preventing fish disease | |
| CN101829211B (en) | Fish compound traditional Chinese medicinal preparation and preparation method thereof | |
| CN101744924B (en) | Multiple-effect Chinese herbal medicine compound of bacterial diseases of turbot | |
| CN105168588B (en) | A kind of Chinese medicine composition and preparation method thereof eaten for fish, application | |
| CN103830628A (en) | Traditional Chinese medicine feed additive for preventing and treating piglet diarrhea and preparation method thereof | |
| CN105395665A (en) | Chinese herbal medicine composition capable of preventing and treating fish and shrimp white stool | |
| CN103283959A (en) | Chinese herbal ultra-fine powder feed additive and its application in culture | |
| CN104491154A (en) | Traditional Chinese medicine ultra-fine powder for treating hemorragic disease of grass carp | |
| CN104814272B (en) | The application of infructescence of Platycarya strobilacea Sieb.et Zucc. Extract | |
| CN104474007B (en) | A kind of antipyretic sweet wormwood licorice root particles for animals and soluble powder preparation and preparation method thereof | |
| CN107088221B (en) | Chinese herbal medicine and medicinal bait for preventing and treating fish trichodiniasis and preparation method thereof | |
| CN103055075B (en) | Pure Chinese medicine composition for the treatment of fishing line parasitosis and taeniasis and preparation method thereof | |
| CN103054985A (en) | Pure Chinese medicinal composition for treating red fin disease of eels and preparation method of pure Chinese medicinal composition | |
| CN107875229B (en) | Composite plant extract for preventing liver and gall syndrome of aquatic animals and preparation method thereof | |
| CN103393891B (en) | Antiviral compound traditional Chinese medicine for animals, and preparation method and use thereof | |
| CN105981921A (en) | Chinese herbal medicinal compound premix for laying hens and manufacturing method thereof | |
| CN1899566A (en) | Medicine for preventing and controlling chicken's infectious rhinitis | |
| CN104273372A (en) | Traditional Chinese herbal feed capable of promoting growth of geese | |
| CN109156610A (en) | A kind of rotten shell disease Chinese herbal feed additive of prevention and treatment Procambius clarkii and the preparation method and application thereof | |
| CN103432242A (en) | Medicine composition for treating giant freshwater prawn white body disease and preparation method thereof | |
| CN101912449B (en) | Medicament for treating hepatitis and preparation technology thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20151021 Termination date: 20160603 |