CN103432242A - Medicine composition for treating giant freshwater prawn white body disease and preparation method thereof - Google Patents

Medicine composition for treating giant freshwater prawn white body disease and preparation method thereof Download PDF

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CN103432242A
CN103432242A CN2013103427682A CN201310342768A CN103432242A CN 103432242 A CN103432242 A CN 103432242A CN 2013103427682 A CN2013103427682 A CN 2013103427682A CN 201310342768 A CN201310342768 A CN 201310342768A CN 103432242 A CN103432242 A CN 103432242A
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herba
weight
medicine composition
pharmaceutical composition
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CN103432242B (en
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房元喧
王松刚
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TAIZHOU CITY CHUNDA ANIMAL PHARMACEUTICAL FEED CO Ltd
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TAIZHOU CITY CHUNDA ANIMAL PHARMACEUTICAL FEED CO Ltd
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Abstract

The invention discloses medicine composition for treating a giant freshwater prawn white body disease, and the medicine composition comprises the following raw materials in parts by weight: 30-40 parts of humifuse euphorbia herb, 15-35 parts of gallnut, 25-35 parts of radix astragali, 23-30 parts of eucalyptus robusta, 20-30 parts of common andrographis herb, 25-35 parts of garden burnet, 25-35 parts of rhizoma menispermi and 13-20 parts of acalypha australis. The invention further discloses a preparation method of the medicine composition. The medicine composition, disclosed by the invention, is reasonable in formula design, fully utilizes the advantages of all raw materials, enhances the effect of bacteria resistance and bacteriostasis, and can effectively treat the giant freshwater prawn white body disease; the contained raw materials are low-toxic traditional Chinese medicines; the cure rate reaches 100%; the provided preparation method is simple and practical; the medicine composition is convenient to feed and suitable for large-scale production.

Description

A kind of pharmaceutical composition for the treatment of Macrobrachium rosenbergii lean type disease and preparation method thereof
Technical field
The present invention relates to treat the field of Chinese medicines of shrimps disease, be specifically related to a kind of pharmaceutical composition for the treatment of Macrobrachium rosenbergii lean type disease and preparation method thereof.
Background technology
The symptom of Macrobrachium rosenbergii lean type disease: sick shrimp body colour is turned white, and especially the tail fan position, progressively extend to forward the position except head.All parts of turning white, muscle is all downright bad, the carapace deliquescing, dead before cephalothorax and abdominal section from.The lighter affects growth, severe one whole heavy water and dead within the time of about 1 week.
Because this disease is just popular in China in recent years, though the research of cause of disease has obtained certain progress, also there is no the supply of commodity diagnostic kit.Mainly rule of thumb reach in production to observe and find disease, usually in breeding spand, at the bottom of the shrimp Seedling of generation nebulousurine disease and pond, form obvious contrast and more easily discovery.Treatment about the lean type disease at present also needs collaborative treatment of Chinese and western medicines, but Western medicine obviously has injury to fish itself, and can cause the food safety hidden danger in later stage.
Goal of the invention: in order to overcome the deficiencies in the prior art, the invention provides a kind of pharmaceutical composition for the treatment of Macrobrachium rosenbergii lean type disease and preparation method thereof.
Technical scheme: in order to solve the problems of the technologies described above, the invention provides a kind of pharmaceutical composition for the treatment of Macrobrachium rosenbergii lean type disease, the raw material by following parts by weight is prepared from: 30 ~ 40 parts of Herba Euphorbiae Humifusaes, 15 ~ 35 parts of Galla Chinensiss, 25 ~ 35 parts of Radix Astragali, 23 ~ 30 parts of Folium Eucalypti Robustae, 20 ~ 30 parts of Herba Andrographis, 25 ~ 35 parts of Radix Sanguisorbaes, 25 ~ 35 parts of Rhizoma Menispermis, 13 ~ 20 parts of Herba Acalyphaes.
Preferably, the raw material by following parts by weight is prepared from: 35 ~ 40 parts of Herba Euphorbiae Humifusaes, 25 ~ 35 parts of Galla Chinensiss, 27 ~ 35 parts of Radix Astragali, 25 ~ 30 parts of Folium Eucalypti Robustae, 25 ~ 30 parts of Herba Andrographis, 28 ~ 35 parts of Radix Sanguisorbaes, 29 ~ 35 parts of Rhizoma Menispermis, 16 ~ 20 parts of Herba Acalyphaes.
Preferably, the raw material by following parts by weight is prepared from: 35 parts of Herba Euphorbiae Humifusaes, 25 parts of Galla Chinensiss, 27 parts of Radix Astragali, 25 parts of Folium Eucalypti Robustae, 25 parts of Herba Andrographis, 28 parts of Radix Sanguisorbaes, 29 parts of Rhizoma Menispermis, 16 parts of Herba Acalyphaes.
The preparation method of the pharmaceutical composition of described treatment Macrobrachium rosenbergii lean type disease comprises the following steps:
1) take each crude drug by above-mentioned parts by weight, and pulverized 400 mesh sieves with super micron mill, make powder;
2) by adding the water of 35 times of powder weight in the powder after pulverizing, add in the pot that is used as medicine and decoct and within 45 minutes, obtain liquid medicine, flame-out;
While 3) being cooled to 25 ℃, according to the weight ratio of liquid medicine: prawn feed=1:30, prawn feed is immersed in liquid medicine 35 minutes, and mixing and stirring, make the hybrid particles of medicine and feedstuff.
Preferably, the particle diameter of described hybrid particles is 1.2 ~ 1.7mm.
The feeding method that contains the pharmaceutical composition that above-mentioned raw materials makes provided by the invention is: at the sick morbidity season of Macrobrachium rosenbergii lean type, aforementioned pharmaceutical compositions is thrown something and fed continuously and thrown something and fed continuously 40 ~ 60 days.
Beneficial effect: pharmaceutical composition recipe design of the present invention is reasonable, and contained drug is low toxicity Chinese medicine, and said composition takes full advantage of the advantage of each medicine, has strengthened the effect of antibacterial bacteriostatic, can effectively treat Macrobrachium rosenbergii lean type disease, and cure rate reaches 100%.Preparation method provided by the invention is simple, the convenience of throwing something and feeding, and is applicable to large-scale production.
The specific embodiment
Below in conjunction with embodiment, the present invention is further described.
embodiment 1:
A kind of pharmaceutical composition for the treatment of Macrobrachium rosenbergii lean type disease, the raw material by following parts by weight is prepared from: 30 parts of Herba Euphorbiae Humifusaes, 15 parts of Galla Chinensiss, 25 parts of Radix Astragali, 23 parts of Folium Eucalypti Robustae, 20 parts of Herba Andrographis, 25 parts of Radix Sanguisorbaes, 25 parts of Rhizoma Menispermis, 13 parts of Herba Acalyphaes.
The preparation method of the pharmaceutical composition of described treatment Macrobrachium rosenbergii lean type disease comprises the following steps:
1) take each crude drug by above-mentioned parts by weight, and pulverized 400 mesh sieves with super micron mill, make powder;
2) by adding the water of 35 times of powder weight in the powder after pulverizing, add in the pot that is used as medicine and decoct and within 45 minutes, obtain liquid medicine, flame-out;
While 3) being cooled to 25 ℃, according to the weight ratio of liquid medicine: prawn feed=1:30, prawn feed is immersed in liquid medicine 35 minutes, and mixing and stirring, make the hybrid particles of medicine and feedstuff.
The particle diameter of described hybrid particles is 1.2mm.
embodiment 2:
A kind of pharmaceutical composition for the treatment of Macrobrachium rosenbergii lean type disease, the raw material by following parts by weight is prepared from: 40 parts of Herba Euphorbiae Humifusaes, 35 parts of Galla Chinensiss, 35 parts of Radix Astragali, 30 parts of Folium Eucalypti Robustae, 30 parts of Herba Andrographis, 35 parts of Radix Sanguisorbaes, 35 parts of Rhizoma Menispermis, 20 parts of Herba Acalyphaes.
The preparation method of the pharmaceutical composition of described treatment Macrobrachium rosenbergii lean type disease comprises the following steps:
1) take each crude drug by above-mentioned parts by weight, and pulverized 400 mesh sieves with super micron mill, make powder;
2) by adding the water of 35 times of powder weight in the powder after pulverizing, add in the pot that is used as medicine and decoct and within 45 minutes, obtain liquid medicine, flame-out;
While 3) being cooled to 25 ℃, according to the weight ratio of liquid medicine: prawn feed=1:30, prawn feed is immersed in liquid medicine 35 minutes, and mixing and stirring, make the hybrid particles of medicine and feedstuff.
The particle diameter of described hybrid particles is 1.7mm.
embodiment 3:
A kind of pharmaceutical composition for the treatment of Macrobrachium rosenbergii lean type disease, the raw material by following parts by weight is prepared from: 35 parts of Herba Euphorbiae Humifusaes, 25 parts of Galla Chinensiss, 27 parts of Radix Astragali, 25 parts of Folium Eucalypti Robustae, 25 parts of Herba Andrographis, 28 parts of Radix Sanguisorbaes, 29 parts of Rhizoma Menispermis, 16 parts of Herba Acalyphaes.
The preparation method of the pharmaceutical composition of described treatment Macrobrachium rosenbergii lean type disease comprises the following steps:
1) take each crude drug by above-mentioned parts by weight, and pulverized 400 mesh sieves with super micron mill, make powder;
2) by adding the water of 35 times of powder weight in the powder after pulverizing, add in the pot that is used as medicine and decoct and within 45 minutes, obtain liquid medicine, flame-out;
While 3) being cooled to 25 ℃, according to the weight ratio of liquid medicine: prawn feed=1:30, prawn feed is immersed in liquid medicine 35 minutes, and mixing and stirring, make the hybrid particles of medicine and feedstuff.
The particle diameter of described hybrid particles is 1.5mm.
The embodiment of the present invention 1 ~ 3 any one pharmaceutical composition usage and consumption: at the sick morbidity season of Macrobrachium rosenbergii lean type, aforementioned pharmaceutical compositions is thrown something and fed continuously and is thrown something and fed continuously 40 ~ 60 days.
Feeding method: cause shrimp death or stop eating when the sick morbidity of lean type appears in the shrimp pool, aforementioned pharmaceutical compositions is thrown something and fed 55 days continuously.
Result of the test: 30 ~ 90 days later treatment phase, shrimp death or the phenomenon of stopping eating do not occur, cure rate 100%.
The above is only the preferred embodiment of the present invention; be noted that for those skilled in the art; under the premise without departing from the principles of the invention, can also make some improvements and modifications, these improvements and modifications also should be considered as protection scope of the present invention.

Claims (5)

1. a pharmaceutical composition for the treatment of Macrobrachium rosenbergii lean type disease, it is characterized in that, the raw material by following parts by weight is prepared from: 30 ~ 40 parts of Herba Euphorbiae Humifusaes, 15 ~ 35 parts of Galla Chinensiss, 25 ~ 35 parts of Radix Astragali, 23 ~ 30 parts of Folium Eucalypti Robustae, 20 ~ 30 parts of Herba Andrographis, 25 ~ 35 parts of Radix Sanguisorbaes, 25 ~ 35 parts of Rhizoma Menispermis, 13 ~ 20 parts of Herba Acalyphaes.
2. pharmaceutical composition according to claim 1, it is characterized in that, the raw material by following parts by weight is prepared from: 35 ~ 40 parts of Herba Euphorbiae Humifusaes, 25 ~ 35 parts of Galla Chinensiss, 27 ~ 35 parts of Radix Astragali, 25 ~ 30 parts of Folium Eucalypti Robustae, 25 ~ 30 parts of Herba Andrographis, 28 ~ 35 parts of Radix Sanguisorbaes, 29 ~ 35 parts of Rhizoma Menispermis, 16 ~ 20 parts of Herba Acalyphaes.
3. pharmaceutical composition according to claim 1, it is characterized in that, the raw material by following parts by weight is prepared from: 35 parts of Herba Euphorbiae Humifusaes, 25 parts of Galla Chinensiss, 27 parts of Radix Astragali, 25 parts of Folium Eucalypti Robustae, 25 parts of Herba Andrographis, 28 parts of Radix Sanguisorbaes, 29 parts of Rhizoma Menispermis, 16 parts of Herba Acalyphaes.
4. the preparation method of the pharmaceutical composition of the described treatment Macrobrachium rosenbergii of claim 1 ~ 3 any one lean type disease, is characterized in that, comprises the following steps:
1) take each crude drug by above-mentioned parts by weight, and pulverized 400 mesh sieves with super micron mill, make powder;
2) by adding the water of 35 times of powder weight in the powder after pulverizing, add in the pot that is used as medicine and decoct and within 45 minutes, obtain liquid medicine, flame-out;
While 3) being cooled to 25 ℃, according to the weight ratio of liquid medicine: prawn feed=1:30, prawn feed is immersed in liquid medicine 35 minutes, and mixing and stirring, make the hybrid particles of medicine and feedstuff.
5. the preparation method of pharmaceutical composition according to claim 4, is characterized in that, the particle diameter of described hybrid particles is 1.2 ~ 1.7mm.
CN201310342768.2A 2013-08-08 2013-08-08 A kind of pharmaceutical composition for the treatment of Macrobrachium rosenbergii lean type disease and preparation method thereof Active CN103432242B (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106819637A (en) * 2016-12-28 2017-06-13 新昌县柏克动物饲料技术开发有限公司 Prevent and treat the feed and preparation method of giant freshwater prawn white body disease
CN107114608A (en) * 2017-05-25 2017-09-01 乐清益昌食品技术有限公司 One kind preventing and treating prawn white body disease feed and preparation method thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1742610A (en) * 2005-09-30 2006-03-08 苏州大学 Anti-stress health-care agent for shrimp and crab
CN102178101A (en) * 2011-04-29 2011-09-14 山东六和集团有限公司 Prawn feed additive, preparation method thereof and composite feed containing additive
CN102715105A (en) * 2012-05-21 2012-10-10 高雷 Industrialization cultivation method for shrimp seed of macrobrachium rosenbergii

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1742610A (en) * 2005-09-30 2006-03-08 苏州大学 Anti-stress health-care agent for shrimp and crab
CN102178101A (en) * 2011-04-29 2011-09-14 山东六和集团有限公司 Prawn feed additive, preparation method thereof and composite feed containing additive
CN102715105A (en) * 2012-05-21 2012-10-10 高雷 Industrialization cultivation method for shrimp seed of macrobrachium rosenbergii

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106819637A (en) * 2016-12-28 2017-06-13 新昌县柏克动物饲料技术开发有限公司 Prevent and treat the feed and preparation method of giant freshwater prawn white body disease
CN107114608A (en) * 2017-05-25 2017-09-01 乐清益昌食品技术有限公司 One kind preventing and treating prawn white body disease feed and preparation method thereof

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