CN105998938A - Feed additive for treating bacterial red skin disease of tilapia mossambica and preparation method therefor - Google Patents
Feed additive for treating bacterial red skin disease of tilapia mossambica and preparation method therefor Download PDFInfo
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- CN105998938A CN105998938A CN201610369906.XA CN201610369906A CN105998938A CN 105998938 A CN105998938 A CN 105998938A CN 201610369906 A CN201610369906 A CN 201610369906A CN 105998938 A CN105998938 A CN 105998938A
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- A61K36/18—Magnoliophyta (angiosperms)
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Abstract
The invention belongs to the technical field of aquaculture, relates to a feed additive for treating bacterial red skin disease of tilapia mossambica, and also relates to a preparation method for the feed additive for treating the bacterial red skin disease of tilapia mossambica. The feed additive for treating the bacterial red skin disease of tilapia mossambica comprises the following components in parts by mass: 30-37 parts of green tea aqueous extract, 24-32 parts of dysosma versipellis, 20-27 parts of herba cirsii, 20-27 parts of rosa roxburghii tratt root, 19-26 parts of herba houttuyniae, 18-26 parts of white poplar bark, 16-25 parts of indian epimeredi herb, 17-25 parts of glutinosae rice root, 14-21 parts of abrus precatorius, 11-18 parts of muskmelon seed, 4-9 parts of gypsum, 4-9 parts of radix paeoniae alba, 6-10 parts of fish oil, 6-10 parts of wild jujube, 12-20 parts of enteromorpha prolifera, 16-20 parts of spirogyra, 16-21 parts of euphausia superba powder and the like. The feed additive prepared by the invention is natural and environment-friendly and can effectively treat bacterial red skin disease of tilapia mossambica.
Description
Technical field
The invention belongs to technical field of aquaculture, particularly relate to a kind of tilapia bacillary erythroderma for the treatment of
Feed additive；The invention still further relates to the feed additive of a kind of above-mentioned bacillary erythroderma for the treatment of tilapia
Preparation method.
Background technology
Tilapia is former is distributed in temperate zone, subtropical zone and tropic countries and area.Tilapia has become as generation now
The cultured freshwater fish that the emphasis scientific research of boundary's aquatic products industry is cultivated, and it is described as the main of following animal protein
One of source.Tilapia originates in Africa, belongs to the tropic fishes of Family Cichlidae, similar with Lateolabrax japonicus (Cuvier et Va-lenciennes) (Lateolabracis), the most raw
Live in fresh water, also can move in the salt water of different salt content, can survive in lake, river, pond
Shallow water in, have the strongest adaptation ability, and the water that dissolved oxygen is less had extremely strong adaptability.The biggest portion
Dividing tilapia is omnivorousness, often eats aquatic plant and minces.Tilapia also can be numerous in the narrow and small waters of area
Grow.Even can grow in rice terrace.
Erythroderma also known as red skin pestilence, wipe skin pestilence etc., respectively breed fish area in China, have popular throughout the year,
But with during water temperature 25-30 DEG C as the time of popularity.The pathogen of erythroderma is Aeromonas, and disease symptom is:
Sick fish is slow in action, bradykinesia, weak, peel off and solely swim in the water surface；Body surface local or large-area hemorrhage are sent out
Inflammation, scale comes off, and particularly fish body both sides and abdominal part is the most obvious；Fin is congested, and afterbody rots, and forms " moth
Fin ", Hubei Province up and down of fish and gill cover part are congested, in block erythema；Sometimes the gill cover is rotten goes one piece, in roundlet
, there is blank in window-like；Depart from scale and often occur that fish molds is parasitic with fin ray rotten place, add severe disease
Gesture, morbidity after a few days will be dead.The main method for the treatment of erythroderma is for using norfloxacin (to use at present
Method is: every 1kg fish body weight is thrown something and fed 30mg every time, mixes to raise and throws something and feeds, 1 day 1 time, is used in conjunction use 3-6 days)
Or bactrim (using method is: every 1kg body weight is thrown something and fed 50mg every time, mixes to raise and throws something and feeds, 1 day 1 time,
Being used in conjunction use 5 days, consumption doubles first).But existing Therapeutic Method and medicine not only therapeutic effect have
Limit, and frequently use antibiotic and easily make Fish develop immunity to drugs, it is unfavorable for that the health of culture fishery can
Sustainable development.
Summary of the invention
An object of the present invention is to provide a kind of feed additive treating the bacillary erythroderma of tilapia, its
Raw material natural environmental-protective, and can effectively treat the bacillary erythroderma of tilapia.
In order to solve above-mentioned technical problem, the present invention by the following technical solutions: one treats tilapia antibacterial
The feed additive of property erythroderma, is made up of each component of following masses number: green tea infusion 30-37 part,
Radix et Rhizoma Dysosmatis 24-32 part, Herba Cirsii 20-27 part, Radix Rosae Normalis 20-27 part, Herba Houttuyniae 19-26 part, Cortex Populi dividianae
Skin 18-26 part, Herba Epimeredis Indicae 16-25 part, Radix Oryzae Glutinosae 17-25 part, Semen Abri Precatorii 14-21 part, Semen Melo 11-18
Part, Folium Isatidis 11-18 part, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 10-17 part, Fructus Hordei Germinatus 8-16 part, Herba Euphorbiae Helioscopiae 7-17 part, Herba Abutili 7-15
Part, phellodendron bark 6-15 part, Folium Mori 6-13 part, Herba Plantaginis 5-12 part, Gypsum Fibrosum 4-9 part, Radix Paeoniae Alba 4-9 part,
Fish oil 6-10 part, Ziziphi Spinosae 6-10 part, Entermorpha 12-20 part, water silk floss 16-20 part, euphausia superba powder 16-21
Part.
Preferably, the feed additive of the described treatment bacillary erythroderma of tilapia, by following masses number
Each component forms: green tea infusion 34 parts, Radix et Rhizoma Dysosmatis 27 parts, Herba Cirsii 24 parts, Radix Rosae Normalis 23 parts, fish
Raw meat grass 23 parts, Cortex Populi Davidianae 21 parts, Herba Epimeredis Indicae 20 parts, Radix Oryzae Glutinosae 20 parts, Semen Abri Precatorii 18 parts, Fructus Melo
Son 15 parts, Folium Isatidis 15 parts, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 13 parts, 12 parts of Fructus Hordei Germinatus, Herba Euphorbiae Helioscopiae 12 parts, Herba Abutili 11 parts,
Phellodendron bark 9 parts, 10 parts of Folium Mori, Herba Plantaginis 9 parts, 6 parts of Gypsum Fibrosum, the Radix Paeoniae Alba 7 parts, 8 parts of fish oil, Ziziphi Spinosae
9 parts, Entermorpha 15 parts, water continuous 18 parts, euphausia superba powder 19 parts.
Preferably, the feed additive of the described treatment bacillary erythroderma of tilapia, by following masses number
Each component forms: green tea infusion 33 parts, Radix et Rhizoma Dysosmatis 28 parts, Herba Cirsii 22 parts, Radix Rosae Normalis 24 parts, fish
Raw meat grass 22 parts, Cortex Populi Davidianae 22 parts, Herba Epimeredis Indicae 21 parts, Radix Oryzae Glutinosae 21 parts, Semen Abri Precatorii 18 parts, Fructus Melo
Son 14 parts, Folium Isatidis 14 parts, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 14 parts, 11 parts of Fructus Hordei Germinatus, Herba Euphorbiae Helioscopiae 12 parts, Herba Abutili 10 parts,
Phellodendron bark 9 parts, 9 parts of Folium Mori, Herba Plantaginis 8 parts, 7 parts of Gypsum Fibrosum, the Radix Paeoniae Alba 6 parts, 8 parts of fish oil, Ziziphi Spinosae 9
Part, Entermorpha 16 parts, water continuous 18 parts, euphausia superba powder 18 parts.
The feed additive of the treatment bacillary erythroderma of tilapia of the present invention, according to bacillary erythroderma
Etiopathogenesis, the suitable component of selection, prepare according to specific ratio and preparation method, can fully send out
Wave the synergistic function between each component, play the function of each component to greatest extent.In the present invention, green
Tea extract, Radix et Rhizoma Dysosmatis, Herba Cirsii, Radix Rosae Normalis, Herba Houttuyniae, Cortex Populi Davidianae, Herba Epimeredis Indicae, Radix Oryzae Glutinosae, phase
Think son, Semen Melo, Folium Isatidis, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.), Fructus Hordei Germinatus, Herba Euphorbiae Helioscopiae, Herba Abutili, phellodendron bark, Folium Mori, Herba Plantaginis,
Pathogen gas unit cell when Gypsum Fibrosum and the Radix Paeoniae Alba are combined with above-mentioned specific proportioning, to tilapia erythroderma
Bacterium has significant bactericidal and bacteriostatic effect.Fish oil can be that tilapia supplements energy, and has tilapia
Food calling effect.Ziziphi Spinosae can appetite promoting and the spleen strengthening, promoting the production of body fluid to quench thirst, help digestion the most stagnant, can promote that tilapia ingests more
The feedstuff of the feed additive that with the addition of the present invention, and then make the nutritional labeling in feedstuff can be for Rofe
Fish preferably supplements the nutrients and muscle power, and makes in the feed additive of the present invention cause of disease to tilapia erythroderma
Bacterium has the composition of notable bactericidal and bacteriostatic effect and enters in tilapia body and play its respective action.Entermorpha and water
Silk floss is the most with low cost, and nutritious, and Appropriate application Entermorpha and water silk floss can reduce Entermorpha and water silk floss band
The environment come and ecological pressure, turn waste into wealth.And Entermorpha and water silk floss not only have food calling effect to tilapia,
And containing abundant nutrition.Euphausia superba powder is nutritious, delicious flavour, also can improve exempting from of tilapia
Epidemic disease power.Additionally, in the present invention, tilapia is had by the tender euphausia superba powder of fish oil, Ziziphi Spinosae, Entermorpha, water
The effect of collaborative food calling, the tender euphausia superba powder of fish oil, Ziziphi Spinosae, Entermorpha, water compounds with above-mentioned special ratios
After, the mouthfeel of feed additive can be improved, energy food calling tilapia ingests and more with the addition of the feedstuff of the present invention
The feedstuff of additive, and then make the nutritional labeling entrance tilapia body in feedstuff interior and utilized by tilapia, also
The pathogen Aeromonas to tilapia erythroderma in feed additive is made to have notable bactericidal and bacteriostatic effect
Composition entrance tilapia body is interior and plays its respective action.
It is a further object of the present invention to provide the feed additive of a kind of above-mentioned bacillary erythroderma for the treatment of tilapia
Preparation method, it comprises the following steps:
(1) being mixed with the mass ratio of 1:20 with purified water by green tea, 60-70 DEG C is soaked 30min-40min,
Filter to obtain green tea infusion；
(2) Radix et Rhizoma Dysosmatis, Herba Cirsii, Radix Rosae Normalis, Herba Houttuyniae, Cortex Populi Davidianae, Radix Saposhnikoviae are weighed respectively according to proportioning
Grass, Radix Oryzae Glutinosae, Semen Abri Precatorii, Semen Melo, Folium Isatidis, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.), Fructus Hordei Germinatus, Herba Euphorbiae Helioscopiae, Herba Abutili, phellodendron bark,
Folium Mori, Herba Plantaginis, Gypsum Fibrosum, the Radix Paeoniae Alba, Ziziphi Spinosae, Entermorpha, the tender euphausia superba powder of water, on load weighted
State each component mix homogeneously and load ball mill grinding, crossing 80 mesh sieves, obtain grounds travel；
(3) fish oil is weighed according to proportioning；
(4) the green tea infusion of step (1) gained is weighed according to proportioning；
(5) grounds travel that load weighted fish oil, green tea infusion obtain with step (2) is mixed homogeneously also
Drying to moisture less than 5%, micropowder is broken to below mean diameter 50 μm, obtains object.
Usage and dosage: every 1kg fish body weight adds the feed additive of the 15-20mg present invention every time, mixes and raises throwing
Hello, 1 day 1 time, it is used in conjunction use 3-5 days.
In preparation method, by green tea purified water 60-70 DEG C soak 30min-40min purpose be by green tea
In effective ingredient fully leach.By Radix et Rhizoma Dysosmatis, Herba Cirsii, Radix Rosae Normalis, Herba Houttuyniae, Cortex Populi Davidianae, Radix Saposhnikoviae
Grass, Radix Oryzae Glutinosae, Semen Abri Precatorii, Semen Melo, Folium Isatidis, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.), Fructus Hordei Germinatus, Herba Euphorbiae Helioscopiae, Herba Abutili, phellodendron bark,
Folium Mori, Herba Plantaginis, Gypsum Fibrosum, the Radix Paeoniae Alba, Ziziphi Spinosae, Entermorpha, the tender euphausia superba powder of water grind purpose be by
Above-mentioned each component is pulverized, is improved its utilization rate.
Additionally, the component of the feed additive of the treatment bacillary erythroderma of tilapia of the present invention is green ring
Protecting raw material, preparation method is nontoxic to environment, does not contains chemical drugs or antibiotic, after edible recovery from illness
Human body will not be brought injury by tilapia, is also beneficial to the sustainable health development of culture fishery；And this
The curative effect of the feed additive erythroderma bacillary to tilapia of invention is good, and cure rate is high, makes ill
The survival rate of tilapia is to more than 90%, and after medication 2-3 days, tilapia " moth fin " phenomenon disappears, fin
Congested and upper and lower Hubei Province, gill cover part hyperemia phenomenon disappear, and scale stops dropping, and the state of an illness is controlled.This
Invention uses safer, and little to tilapia damage, the treatment tilapia using the present invention is bacillary red
After the feed additive that skin is sick, tilapia Health restoration is fast, throws something and feeds 2-4 days, and tilapia can recover normal
Activity, idle fund is strong and vigorous, and wound progressively heals, and ingests and progressively recovers normal.
Compared with prior art, the invention has the beneficial effects as follows:
(1) feed additive of the treatment bacillary erythroderma of tilapia of the present invention, is according to bacillary red skin
Sick etiopathogenesis, the suitable component of selection, prepare according to specific ratio and preparation method, Ke Yichong
The synergistic function between each component is waved in distribution, plays the function of each component to greatest extent.In the present invention,
Green tea infusion, Radix et Rhizoma Dysosmatis, Herba Cirsii, Radix Rosae Normalis, Herba Houttuyniae, Cortex Populi Davidianae, Herba Epimeredis Indicae, Radix Oryzae Glutinosae,
Semen Abri Precatorii, Semen Melo, Folium Isatidis, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.), Fructus Hordei Germinatus, Herba Euphorbiae Helioscopiae, Herba Abutili, phellodendron bark, Folium Mori, Herba Plantaginis
When grass, Gypsum Fibrosum and the Radix Paeoniae Alba are combined with above-mentioned specific proportioning, the pathogen gas to tilapia erythroderma
Zymomonas mobilis has significant bactericidal and bacteriostatic effect.Fish oil can be that tilapia supplements energy, and to tilapia
There is food calling effect.Ziziphi Spinosae can appetite promoting and the spleen strengthening, promoting the production of body fluid to quench thirst, help digestion the most stagnant, can promote that tilapia ingests
More with the addition of the feedstuff of the feed additive of the present invention, and then make the nutritional labeling in feedstuff to be
Tilapia preferably supplements the nutrients and muscle power, and makes in the feed additive of the present invention tilapia erythroderma
Pathogen Aeromonas has the composition of notable bactericidal and bacteriostatic effect and enters in tilapia body and play it and make accordingly
With.Entermorpha and water silk floss are the most with low cost, and nutritious, and Appropriate application Entermorpha and water silk floss can reduce
Environment that Entermorpha and water silk floss bring and ecological pressure, turn waste into wealth.And Entermorpha and water silk floss are not only to Rofe fishing gear
There is food calling effect, and containing abundant nutrition.Euphausia superba powder is nutritious, delicious flavour, also can carry
The immunity of high tilapia.Additionally, in the present invention, the tender euphausia superba powder of fish oil, Ziziphi Spinosae, Entermorpha, water
Have the effect of collaborative food calling to tilapia, the tender euphausia superba powder of fish oil, Ziziphi Spinosae, Entermorpha, water is with above-mentioned
After special ratios is compounding, can improve the mouthfeel of feed additive, energy food calling tilapia ingests and more with the addition of
The feedstuff of the feed additive of the present invention, and then in making nutritional labeling in feedstuff enter tilapia body and by sieve
Non-fish utilizes, and also makes the pathogen Aeromonas to tilapia erythroderma in feed additive have and significantly kills
The composition entrance tilapia body of bacterium fungistatic effect is interior and plays its respective action.
(2), in preparation method, by green tea purified water in the purpose that 60-70 DEG C is soaked 30min-40min it is
Effective ingredient in green tea is fully leached.By Radix et Rhizoma Dysosmatis, Herba Cirsii, Radix Rosae Normalis, Herba Houttuyniae, Cortex Populi Davidianae,
Herba Epimeredis Indicae, Radix Oryzae Glutinosae, Semen Abri Precatorii, Semen Melo, Folium Isatidis, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.), Fructus Hordei Germinatus, Herba Euphorbiae Helioscopiae, Herba Abutili, Huang
The mesh that cypress skin, Folium Mori, Herba Plantaginis, Gypsum Fibrosum, the Radix Paeoniae Alba, Ziziphi Spinosae, Entermorpha, the tender euphausia superba powder of water are ground
Be by above-mentioned each component pulverize, improve its utilization rate.
(3) component of the feed additive of the treatment bacillary erythroderma of tilapia of the present invention is environmental protection
Raw material, preparation method is nontoxic to environment, does not contains chemical drugs or antibiotic, sieve after edible recovery from illness
Human body will not be brought injury by non-fish, is also beneficial to the sustainable health development of culture fishery；And this
The curative effect of bright feed additive erythroderma bacillary to tilapia is good, and cure rate is high, makes ill sieve
The survival rate of non-fish is to more than 90%, and after medication 2-3 days, tilapia " moth fin " phenomenon disappears, and fin fills
Blood and up and down Hubei Province, gill cover part hyperemia phenomenon disappear, and scale stops dropping, and the state of an illness is controlled.This
Bright use safer, to tilapia damage little, use the present invention the bacillary red skin for the treatment of tilapia
After sick feed additive, tilapia Health restoration is fast, throws something and feeds 2-4 days, and tilapia can recover normal and live
Dynamic, idle fund is strong and vigorous, and wound progressively heals, and ingests and progressively recovers normal.
Detailed description of the invention
Below example facilitates a better understanding of the present invention, but does not limit the present invention.In following embodiment
Experimental technique, if no special instructions, be conventional method.
Embodiment 1
A kind of feed additive treating the bacillary erythroderma of tilapia, by each component group of following masses number
Become: green tea infusion 30 parts, Radix et Rhizoma Dysosmatis 25 parts, Herba Cirsii 21 parts, Radix Rosae Normalis 20 parts, Herba Houttuyniae 19 parts,
Cortex Populi Davidianae 18 parts, Herba Epimeredis Indicae 18 parts, Radix Oryzae Glutinosae 17 parts, Semen Abri Precatorii 14 parts, Semen Melo 11 parts, big
Folium Isatidis 11 parts, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 10 parts, 8 parts of Fructus Hordei Germinatus, Herba Euphorbiae Helioscopiae 7 parts, Herba Abutili 7 parts, phellodendron bark 6 parts, Mulberry
6 parts of leaf, Herba Plantaginis 5 parts, 4 parts of Gypsum Fibrosum, the Radix Paeoniae Alba 4 parts, 6 parts of fish oil, Ziziphi Spinosae 9 parts, Entermorpha 12 parts,
Water continuous 16 parts, euphausia superba powder 17 parts.
The preparation method of the feed additive of the above-mentioned bacillary erythroderma for the treatment of tilapia comprises the following steps:
(1) being mixed with the mass ratio of 1:20 with purified water by green tea, 60-70 DEG C is soaked 30min-40min,
Filter to obtain green tea infusion；
(2) Radix et Rhizoma Dysosmatis, Herba Cirsii, Radix Rosae Normalis, Herba Houttuyniae, Cortex Populi Davidianae, Radix Saposhnikoviae are weighed respectively according to proportioning
Grass, Radix Oryzae Glutinosae, Semen Abri Precatorii, Semen Melo, Folium Isatidis, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.), Fructus Hordei Germinatus, Herba Euphorbiae Helioscopiae, Herba Abutili, phellodendron bark,
Folium Mori, Herba Plantaginis, Gypsum Fibrosum, the Radix Paeoniae Alba, Ziziphi Spinosae, Entermorpha, the tender euphausia superba powder of water, on load weighted
State each component mix homogeneously and load ball mill grinding, crossing 80 mesh sieves, obtain grounds travel；
(3) fish oil is weighed according to proportioning；
(4) the green tea infusion of step (1) gained is weighed according to proportioning；
(5) grounds travel that load weighted fish oil, green tea infusion obtain with step (2) is mixed homogeneously also
Drying to moisture less than 5%, micropowder is broken to below mean diameter 50 μm, obtains object.
Embodiment 2
A kind of feed additive treating the bacillary erythroderma of tilapia, by each component group of following masses number
Become: green tea infusion 33 parts, Radix et Rhizoma Dysosmatis 24 parts, Herba Cirsii 20 parts, Radix Rosae Normalis 21 parts, Herba Houttuyniae 20 parts,
Cortex Populi Davidianae 18 parts, Herba Epimeredis Indicae 16 parts, Radix Oryzae Glutinosae 17 parts, Semen Abri Precatorii 14 parts, Semen Melo 14 parts, big
Folium Isatidis 11 parts, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 10 parts, 9 parts of Fructus Hordei Germinatus, Herba Euphorbiae Helioscopiae 7 parts, Herba Abutili 8 parts, phellodendron bark 6 parts, Mulberry
7 parts of leaf, Herba Plantaginis 5 parts, 5 parts of Gypsum Fibrosum, the Radix Paeoniae Alba 4 parts, 7 parts of fish oil, Ziziphi Spinosae 6 parts, Entermorpha 15 parts,
Water continuous 16 parts, euphausia superba powder 16 parts.
The preparation method of the feed additive of the treatment bacillary erythroderma of tilapia of the present embodiment is with embodiment 1.
Embodiment 3
A kind of feed additive treating the bacillary erythroderma of tilapia, by each component group of following masses number
Become: green tea infusion 37 parts, Radix et Rhizoma Dysosmatis 32 parts, Herba Cirsii 27 parts, Radix Rosae Normalis 25 parts, Herba Houttuyniae 22 parts,
Cortex Populi Davidianae 26 parts, Herba Epimeredis Indicae 25 parts, Radix Oryzae Glutinosae 25 parts, Semen Abri Precatorii 21 parts, Semen Melo 18 parts, big
Folium Isatidis 18 parts, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 17 parts, 16 parts of Fructus Hordei Germinatus, Herba Euphorbiae Helioscopiae 17 parts, Herba Abutili 15 parts, phellodendron bark 12 parts,
13 parts of Folium Mori, Herba Plantaginis 12 parts, 9 parts of Gypsum Fibrosum, the Radix Paeoniae Alba 9 parts, 10 parts of fish oil, Ziziphi Spinosae 10 parts, waterside
Tongue 20 parts, water continuous 20 parts, euphausia superba powder 18 parts.
The preparation method of the feed additive of the treatment bacillary erythroderma of tilapia of the present embodiment is with embodiment 1.
Embodiment 4
A kind of feed additive treating the bacillary erythroderma of tilapia, by each component group of following masses number
Become: green tea infusion 35 parts, Radix et Rhizoma Dysosmatis 32 parts, Herba Cirsii 26 parts, Radix Rosae Normalis 27 parts, Herba Houttuyniae 26 parts,
Cortex Populi Davidianae 26 parts, Herba Epimeredis Indicae 24 parts, Radix Oryzae Glutinosae 24 parts, Semen Abri Precatorii 21 parts, Semen Melo 14 parts, big
Folium Isatidis 18 parts, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 15 parts, 10 parts of Fructus Hordei Germinatus, Herba Euphorbiae Helioscopiae 14 parts, Herba Abutili 14 parts, phellodendron bark 15 parts,
13 parts of Folium Mori, Herba Plantaginis 12 parts, 8 parts of Gypsum Fibrosum, the Radix Paeoniae Alba 9 parts, 9 parts of fish oil, Ziziphi Spinosae 9 parts, Entermorpha
20 parts, water continuous 20 parts, euphausia superba powder 21 parts.
The preparation method of the feed additive of the treatment bacillary erythroderma of tilapia of the present embodiment is with embodiment 1.
Embodiment 5
A kind of feed additive treating the bacillary erythroderma of tilapia, by each component group of following masses number
Become: green tea infusion 34 parts, Radix et Rhizoma Dysosmatis 27 parts, Herba Cirsii 24 parts, Radix Rosae Normalis 23 parts, Herba Houttuyniae 23 parts,
Cortex Populi Davidianae 21 parts, Herba Epimeredis Indicae 20 parts, Radix Oryzae Glutinosae 20 parts, Semen Abri Precatorii 18 parts, Semen Melo 15 parts, big
Folium Isatidis 15 parts, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 13 parts, 12 parts of Fructus Hordei Germinatus, Herba Euphorbiae Helioscopiae 12 parts, Herba Abutili 11 parts, phellodendron bark 9 parts,
10 parts of Folium Mori, Herba Plantaginis 9 parts, 6 parts of Gypsum Fibrosum, the Radix Paeoniae Alba 7 parts, 8 parts of fish oil, Ziziphi Spinosae 9 parts, Entermorpha 15
Part, water continuous 18 parts, euphausia superba powder 19 parts.
The preparation method of the feed additive of the treatment bacillary erythroderma of tilapia of the present embodiment is with embodiment 1.
Embodiment 6
A kind of feed additive treating the bacillary erythroderma of tilapia, by each component group of following masses number
Become: green tea infusion 33 parts, Radix et Rhizoma Dysosmatis 28 parts, Herba Cirsii 22 parts, Radix Rosae Normalis 24 parts, Herba Houttuyniae 22 parts,
Cortex Populi Davidianae 22 parts, Herba Epimeredis Indicae 21 parts, Radix Oryzae Glutinosae 21 parts, Semen Abri Precatorii 18 parts, Semen Melo 14 parts, big
Folium Isatidis 14 parts, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 14 parts, 11 parts of Fructus Hordei Germinatus, Herba Euphorbiae Helioscopiae 12 parts, Herba Abutili 10 parts, phellodendron bark 9 parts,
9 parts of Folium Mori, Herba Plantaginis 8 parts, 7 parts of Gypsum Fibrosum, the Radix Paeoniae Alba 6 parts, 8 parts of fish oil, Ziziphi Spinosae 9 parts, Entermorpha 16
Part, water continuous 18 parts, euphausia superba powder 18 parts.
The preparation method of the feed additive of the treatment bacillary erythroderma of tilapia of the present embodiment is with embodiment 1.
Experimental result
In order to verify the therapeutic effect of the present invention, the tilapia suffering from bacillary erythroderma is being carried out treatment effect
The inspection of fruit, each experimental group and matched group be respectively provided with two repetition, and the standard that sick fish is fully recovered is tilapia
" moth fin " phenomenon disappears, and the congested and upper and lower Hubei Province of fin, gill cover part hyperemia phenomenon disappear, and scale stops
Dropping, the state of an illness is controlled, and the process of experimental group and matched group is as follows:
The process of matched group is as follows: every 1kg fish body weight is thrown something and fed 50mg bactrim every time, mixes to raise and throws something and feeds, and 1
It 1 time, consumption doubles first, is used in conjunction use until sick fish is fully recovered.
The process of experiment A group is as follows: every 1kg fish body weight is added the feedstuff of the 18mg embodiment of the present invention 1 every time and added
Agent, mixes to raise and throws something and feeds, 1 day 1 time, until sick fish recovery from illness.
The process of experiment B group is as follows: every 1kg fish body weight is added the feedstuff of the 18mg embodiment of the present invention 2 every time and added
Agent, mixes to raise and throws something and feeds, 1 day 1 time, until sick fish recovery from illness.
The process of experiment C group is as follows: every 1kg fish body weight is added the feedstuff of the 18mg embodiment of the present invention 3 every time and added
Agent, mixes to raise and throws something and feeds, 1 day 1 time, until sick fish recovery from illness.
The process of experiment D group is as follows: every 1kg fish body weight is added the feedstuff of the 18mg embodiment of the present invention 4 every time and added
Agent, mixes to raise and throws something and feeds, 1 day 1 time, until sick fish recovery from illness.
The process of experiment E group is as follows: every 1kg fish body weight is added the feedstuff of the 18mg embodiment of the present invention 5 every time and added
Agent, mixes to raise and throws something and feeds, 1 day 1 time, until sick fish recovery from illness.
The process of experiment F group is as follows: every 1kg fish body weight is added the feedstuff of the 18mg embodiment of the present invention 6 every time and added
Agent, mixes to raise and throws something and feeds, 1 day 1 time, until sick fish recovery from illness.
Experimental result is shown in Table 1:
The feed additive therapeutic effect of the treatment bacillary erythroderma of tilapia of table 1 present invention
In the present invention, green tea infusion, Radix et Rhizoma Dysosmatis, Herba Cirsii, Radix Rosae Normalis, Herba Houttuyniae, Cortex Populi Davidianae, anti-
Wind grass, Radix Oryzae Glutinosae, Semen Abri Precatorii, Semen Melo, Folium Isatidis, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.), Fructus Hordei Germinatus, Herba Euphorbiae Helioscopiae, Herba Abutili, Cortex Phellodendri
When skin, Folium Mori, Herba Plantaginis, Gypsum Fibrosum and the Radix Paeoniae Alba are combined with above-mentioned specific proportioning, red to tilapia
The pathogen Aeromonas of skin disease has significant bactericidal and bacteriostatic effect.Fish oil can be that tilapia supplements energy,
And tilapia is had food calling effect.Ziziphi Spinosae can appetite promoting and the spleen strengthening, promoting the production of body fluid to quench thirst, help digestion the most stagnant, can promote
Enter tilapia to ingest the feedstuff of the feed additive that more with the addition of the present invention, and then make the battalion in feedstuff
Form point and can preferably supplement the nutrients for tilapia and muscle power, and make in the feed additive of the present invention sieve
The pathogen Aeromonas of non-red skin has the composition of notable bactericidal and bacteriostatic effect and enters in tilapia body also
Play its respective action.Entermorpha and water silk floss are the most with low cost, and nutritious, Appropriate application Entermorpha and
Water silk floss can reduce Entermorpha and water silk floss brings environment and ecological pressure, turn waste into wealth.And Entermorpha and water silk floss are not
Only tilapia is had food calling effect, and containing abundant nutrition.Euphausia superba powder is nutritious, taste
Deliciousness, also can improve the immunity of tilapia.Additionally, in the present invention, fish oil, Ziziphi Spinosae, Entermorpha, water are continuous
With the effect that euphausia superba powder has collaborative food calling to tilapia, the tender South Pole of fish oil, Ziziphi Spinosae, Entermorpha, water
After krill meal compounds with above-mentioned special ratios, the mouthfeel of feed additive can be improved, can ingest by food calling tilapia
More with the addition of the feedstuff of the feed additive of the present invention, and then make the nutritional labeling in feedstuff enter Rofe
In fish body and utilized by tilapia, also make the pathogen gas unit cell to tilapia erythroderma in feed additive
Bacterium has the composition of notable bactericidal and bacteriostatic effect and enters in tilapia body and play its respective action.
It is former that the component of the feed additive of the treatment bacillary erythroderma of tilapia of the present invention is environmental protection
Material, preparation method is nontoxic to environment, does not contains chemical drugs or antibiotic, the Rofe after edible recovery from illness
Human body will not be brought injury by fish, is also beneficial to the sustainable health development of culture fishery.Experimental result table
Bright, the curative effect of the feed additive of present invention erythroderma bacillary to tilapia is good, and cure rate is high, makes
The survival rate of ill tilapia is to more than 90%, and after medication 2-3 days, tilapia " moth fin " phenomenon disappears,
Congested and the upper and lower Hubei Province of fin, gill cover part hyperemia phenomenon disappear, and scale stops dropping, and the state of an illness is controlled.
The present invention uses safer, and little to tilapia damage, the treatment tilapia using the present invention is bacillary
After the feed additive of erythroderma, tilapia Health restoration is fast, throws something and feeds 2-4 days, and tilapia can recover normal
Activity, idle fund is strong and vigorous, and wound progressively heals, and ingests and progressively recovers normal.
Bacteriostatic test checks
With bactrim as matched group, the treatment tilapia of embodiment of the present invention 1-embodiment 6 is bacillary red
The feed additive of skin disease is that experimental group carries out antibacterial inspection contrast.
Culture medium: LB culture medium.
Strain is: Aeromonas.
Matched group antibacterial liquid is prepared: is dissolved in sterile deionized water by bactrim, makes the new promise of compound recipe
Bright content is 0.02mg/ml.
Experimental group antibacterial liquid is prepared: by the bacillary erythroderma for the treatment of tilapia of embodiment of the present invention 1-embodiment 6
Feed additive be dissolved in respectively in sterile deionized water, being diluted to concentration respectively is 0.02mg/ml.
Observe and record experimental result:
Represent with "-" without inhibition zone；
Antibacterial circle diameter ＜ 10mm is the most antibacterial, with "+" represent；
Antibacterial circle diameter 10～14mm is that moderate is antibacterial, represents with " ++ "；
Antibacterial circle diameter ＞ 14mm is that height is antibacterial, represents with " +++ "；The fungistatic effect of Aeromonas is shown in
Table 2:
The bactericidal and bacteriostatic effect of the feed additive of the treatment bacillary erythroderma of tilapia of table 2 present invention
From table 2, the feed additive of the treatment bacillary erythroderma of tilapia of the present invention is to bacillary red skin
Sick pathogen Aeromonas, has good bactericidal and bacteriostatic effect.
The above is only the preferred embodiment of the present invention, it should be pointed out that: common for the art
For technical staff, under the premise without departing from the principles of the invention, it is also possible to make some improvement, these change
Enter to should be regarded as protection scope of the present invention.
Claims (4)
1. the feed additive treating the bacillary erythroderma of tilapia, it is characterised in that: by following masses
Number each component composition: green tea infusion 30-37 part, Radix et Rhizoma Dysosmatis 24-32 part, Herba Cirsii 20-27 part,
Radix Rosae Normalis 20-27 part, Herba Houttuyniae 19-26 part, Cortex Populi Davidianae 18-26 part, Herba Epimeredis Indicae 16-25 part, glutinous
Rice root 17-25 part, Semen Abri Precatorii 14-21 part, Semen Melo 11-18 part, Folium Isatidis 11-18 part, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.)
10-17 part, Fructus Hordei Germinatus 8-16 part, Herba Euphorbiae Helioscopiae 7-17 part, Herba Abutili 7-15 part, phellodendron bark 6-15 part, Folium Mori
6-13 part, Herba Plantaginis 5-12 part, Gypsum Fibrosum 4-9 part, Radix Paeoniae Alba 4-9 part, fish oil 6-10 part, Ziziphi Spinosae 6-10
Part, Entermorpha 12-20 part, water silk floss 16-20 part, euphausia superba powder 16-21 part.
The feed additive of the treatment bacillary erythroderma of tilapia the most according to claim 1, its feature
It is: the feed additive of the described treatment bacillary erythroderma of tilapia, by each component of following masses number
Composition: green tea infusion 34 parts, Radix et Rhizoma Dysosmatis 27 parts, Herba Cirsii 24 parts, Radix Rosae Normalis 23 parts, Herba Houttuyniae 23
Part, Cortex Populi Davidianae 21 parts, Herba Epimeredis Indicae 20 parts, Radix Oryzae Glutinosae 20 parts, Semen Abri Precatorii 18 parts, Semen Melo 15 parts,
Folium Isatidis 15 parts, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 13 parts, 12 parts of Fructus Hordei Germinatus, Herba Euphorbiae Helioscopiae 12 parts, Herba Abutili 11 parts, phellodendron bark 9 parts,
10 parts of Folium Mori, Herba Plantaginis 9 parts, 6 parts of Gypsum Fibrosum, the Radix Paeoniae Alba 7 parts, 8 parts of fish oil, Ziziphi Spinosae 9 parts, Entermorpha 15
Part, water continuous 18 parts, euphausia superba powder 19 parts.
The feed additive of the treatment bacillary erythroderma of tilapia the most according to claim 1, its feature
It is: the feed additive of the described treatment bacillary erythroderma of tilapia, by each component of following masses number
Composition: green tea infusion 33 parts, Radix et Rhizoma Dysosmatis 28 parts, Herba Cirsii 22 parts, Radix Rosae Normalis 24 parts, Herba Houttuyniae 22
Part, Cortex Populi Davidianae 22 parts, Herba Epimeredis Indicae 21 parts, Radix Oryzae Glutinosae 21 parts, Semen Abri Precatorii 18 parts, Semen Melo 14 parts,
Folium Isatidis 14 parts, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 14 parts, 11 parts of Fructus Hordei Germinatus, Herba Euphorbiae Helioscopiae 12 parts, Herba Abutili 10 parts, phellodendron bark 9 parts,
9 parts of Folium Mori, Herba Plantaginis 8 parts, 7 parts of Gypsum Fibrosum, the Radix Paeoniae Alba 6 parts, 8 parts of fish oil, Ziziphi Spinosae 9 parts, Entermorpha 16
Part, water continuous 18 parts, euphausia superba powder 18 parts.
4. the feedstuff of the treatment bacillary erythroderma of tilapia according to any one of claim 1-3 adds
The preparation method of agent, it is characterised in that: comprise the following steps:
(1) being mixed with the mass ratio of 1:20 with purified water by green tea, 60-70 DEG C is soaked 30min-40min,
Filter to obtain green tea infusion；
(2) Radix et Rhizoma Dysosmatis, Herba Cirsii, Radix Rosae Normalis, Herba Houttuyniae, Cortex Populi Davidianae, Radix Saposhnikoviae are weighed respectively according to proportioning
Grass, Radix Oryzae Glutinosae, Semen Abri Precatorii, Semen Melo, Folium Isatidis, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.), Fructus Hordei Germinatus, Herba Euphorbiae Helioscopiae, Herba Abutili, phellodendron bark,
Folium Mori, Herba Plantaginis, Gypsum Fibrosum, the Radix Paeoniae Alba, Ziziphi Spinosae, Entermorpha, the tender euphausia superba powder of water, on load weighted
State each component mix homogeneously and load ball mill grinding, crossing 80 mesh sieves, obtain grounds travel；
(3) fish oil is weighed according to proportioning；
(4) the green tea infusion of step (1) gained is weighed according to proportioning；
(5) grounds travel that load weighted fish oil, green tea infusion obtain with step (2) is mixed homogeneously also
Drying to moisture less than 5%, micropowder is broken to below mean diameter 50 μm, obtains object.
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| CN201610369906.XA CN105998938A (en) | 2016-05-30 | 2016-05-30 | Feed additive for treating bacterial red skin disease of tilapia mossambica and preparation method therefor |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106490402A (en) * | 2016-10-28 | 2017-03-15 | 青岛海之星生物科技有限公司 | A kind of feed addictive for treating colored perch red skin disease and preparation method thereof |
| CN107047962A (en) * | 2017-05-16 | 2017-08-18 | 广东海因特生物技术集团有限公司 | It is a kind of to prevent and treat feed addictive that bream red skin disease becomes and its preparation method and application |
| CN109122424A (en) * | 2018-09-17 | 2019-01-04 | 海南儋州翔泰养殖有限公司 | A kind of control method of Tilapia mossambica bacterial infection |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105396110A (en) * | 2015-12-22 | 2016-03-16 | 青岛海之源智能技术有限公司 | Powder used for preventing branchiomycosis of tilapia and preparation method thereof |
| CN105412670A (en) * | 2015-12-22 | 2016-03-23 | 青岛海之源智能技术有限公司 | Immunopotentiator for preventing and treating tilapia branchiomycosis and preparation method thereof |
-
2016
- 2016-05-30 CN CN201610369906.XA patent/CN105998938A/en not_active Withdrawn
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105396110A (en) * | 2015-12-22 | 2016-03-16 | 青岛海之源智能技术有限公司 | Powder used for preventing branchiomycosis of tilapia and preparation method thereof |
| CN105412670A (en) * | 2015-12-22 | 2016-03-23 | 青岛海之源智能技术有限公司 | Immunopotentiator for preventing and treating tilapia branchiomycosis and preparation method thereof |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106490402A (en) * | 2016-10-28 | 2017-03-15 | 青岛海之星生物科技有限公司 | A kind of feed addictive for treating colored perch red skin disease and preparation method thereof |
| CN107047962A (en) * | 2017-05-16 | 2017-08-18 | 广东海因特生物技术集团有限公司 | It is a kind of to prevent and treat feed addictive that bream red skin disease becomes and its preparation method and application |
| CN107047962B (en) * | 2017-05-16 | 2020-03-13 | 广东海大集团股份有限公司 | Feed additive for preventing and treating red skin lesion of bream and preparation method and application thereof |
| CN109122424A (en) * | 2018-09-17 | 2019-01-04 | 海南儋州翔泰养殖有限公司 | A kind of control method of Tilapia mossambica bacterial infection |
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