CN102309564A - Anti-stress drug used for aquatic livestock and its preparation method - Google Patents
Anti-stress drug used for aquatic livestock and its preparation method Download PDFInfo
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- CN102309564A CN102309564A CN201110185494A CN201110185494A CN102309564A CN 102309564 A CN102309564 A CN 102309564A CN 201110185494 A CN201110185494 A CN 201110185494A CN 201110185494 A CN201110185494 A CN 201110185494A CN 102309564 A CN102309564 A CN 102309564A
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Abstract
The invention relates to an anti-stress drug used for aquatic livestock and its preparation method, the drug comprises the following raw medicines by weight: 5-15 parts of seed of wild jujube, 10-30 parts of acanthopanax, 5-15 parts of shizandra berry, 5-15 parts of liquorice and 25-75 parts of carriers. The preparation method of anti-stress drug used for aquatic livestock comprises the following steps: crushing the raw medicines and screening by a sieve of 20-80 meshes, weighting 5-15 parts of seed of wild jujube, 10-30 parts of acanthopanax, 5-15 parts of shizandra berry, 5-15 parts of liquorice and 25-75 parts of carriers according to weight parts, uniformly mixing to obtain the drug. The anti-stress drug used for aquatic livestock are organically combined and supplement each other, not only has anti-stress effect, but also can improve the ingestion rate of the aquatic livestock, promote the growth of the aquatic livestock, and greatly improve the immunity of aquatic animal organisms. The anti-stress drug has the advantages of reasonable formula, simple preparation, low cost, convenient use, wide application scope and obvious effect.
Description
Technical field
The present invention relates to a kind of aquatic animal institute medicament and preparation method thereof, particularly a kind of aquatic animal is with anti-stress medicine and preparation method thereof.
Background technology
At present; In the aquaculture process, breed objects such as fish shrimp crab will be faced with the stimulus effects of more and more stressors unavoidably, like water pollution, the cold and hot sudden change of weather, long-distance transport etc.; These stress in various degree; The normal growth that not only can directly influence aquatic animal is grown, and the decline of the immunity of organisms of serious caused fish shrimp crab, induces an illness even death.Therefore; Reduce or eliminate the stressors of culturing fish and shrimp; Except carrying out the scientific feeding management; Also should be as the case may be, in bait, add relevant anti-stress feed addictive, utilizing Chinese herbal medicine to strengthen aquatic animal body anti allergic reaction is one of this field scientific research technical staff important difficult problem of being badly in need of solving.
Summary of the invention
The objective of the invention is to overcome deficiency of the prior art, but the aquatic animal that a kind of not only external but also oral administration be provided is with anti-stress medicine and preparation method thereof.
For realizing above-mentioned purpose, the technical scheme that the present invention adopted is following:
Anti-stress medicine is used in a kind of aquatic animal, it is characterized in that being formed by following portions by weight proportion raw material medicine mixed preparing: 5～15 parts of Semen Ziziphi Spinosaes, 10～30 parts of Radix Et Caulis Acanthopanacis Senticosis, 5～15 parts of Fructus Schisandrae Chinensis, 5～15 parts in Radix Glycyrrhizae, 25～75 parts in carrier.
Said carrier is more than one in starch, zeolite powder, the glucose.
This process for preparing medicine carries out as follows:
Following various crude drug are pulverized 20～80 mesh sieves, took by weighing 5～15 parts of Semen Ziziphi Spinosaes by weight, 10～30 parts of Radix Et Caulis Acanthopanacis Senticosis, 5～15 parts of Fructus Schisandrae Chinensis, 5～15 parts in Radix Glycyrrhizae, 25～75 parts in carrier, uniform mixing.
The various crude drug characteristics that the present invention adopts are following:
Semen Ziziphi Spinosae: nature and flavor are sweet, and are flat, GUIXIN, liver, gallbladder meridian.Belong to calm, calm the nerves, convulsion class Chinese herbal medicine.It contains volume fatty oil, protein and volume vitamin C.Semen Ziziphi Spinosae can improve body to anoxybiotic tolerance, with the Fructus Schisandrae Chinensis compatibility also the deferrable Burn shock in rats generation and prolong the time-to-live.
Radix Et Caulis Acanthopanacis Senticosi: nature and flavor are hot, bitter, little sweet; Warm in nature.Return Liver Channel; Kidney channel.QI invigorating class Chinese herbal medicine thorn contains through researching and analysing Main Ingredients and Appearance: the carotene of multiple carbohydrate, aminoacid, fatty acid, vitamin A, B1, B2 and volume; Other contains sesamin, sterol, coumarin, flavone, suberone, non-armaticity unsaturated organic acid and multiple trace mineral etc.Radix Et Caulis Acanthopanacis Senticosi can change the pathological process of body to stress, can also prolong the opposing phase to stress simultaneously.
Fructus Schisandrae Chinensis: warm in nature, sour, sweet; Return lung, the heart, kidney channel.Belong to nourishing YIN and supplementing blood class Chinese herbal medicine.Chemical constituent has schizandrin, deoxyschisandrin, newly son element, schisandrol, schizantherin etc. simply.Fructus Schisandrae Chinensis aqueous solution lumbar injection can obviously prolong the normal pressure anoxia enduring time-to-live of mice.
Radix Glycyrrhizae: property is flat, and sweet in the mouth is returned 12 warps.Belong to QI invigorating class Chinese herbal medicine, the main chemical compositions glycyrrhizic acid.Recent study shows that glycyrrhizic acid and its esters glycyrrhizin have effects such as antiinflammatory, antiviral, the influence to the mouse liver cell apoptosis, immunomodulating and blood fat reducing.
Starch: mainly play binding agent at this.
Zeolite powder: zeolite has unique mineral structure, and its structure is three-dimensional silicon-oxy tetrahedron and three-dimensional aluminum-oxygen tetrahedron, and these tetrahedrons are arranged in the crystalline framework with definite shape according to certain rules.The mineral skeleton of zeolite is one open, has a lot of uniform passage and cavity, in these holes and passage, is adsorbing metal cation and hydrone, the adhesion between these cationes and hydrone and anion frame a little less than.This special construction of zeolite has determined its peculiar performance.The inner hole of zeolite crystal accounts for the over half of crystal cumulative volume with the volume of passage, in hole and passage, has many zeolite waters, and warp heats the moisture mistake of can escaping.Zeolite after the dehydration has formed the very big hole of surface area, and the internal surface area of a gram zeolite hole and passage can reach 500～1000 square metres.It has very strong adsorptivity this loose structure decision.Adsorbable a large amount of polar molecule (like ammonia, carbon dioxide, hydrogen sulfide etc.) that has, every mu of depth of water is used zeolite powder (200 order) 50kg for 1 meter, can remove ammonia nitrogen 95% in the water, purifies water, and alleviating changes the water phenomenon.When TAN in the shrimp pond surpass to allow one times of content, promptly reach 1.2mg/L, use zeolite 16mg/L to handle after, can make pond water ammonia-nitrogen content reduce to safe concentration.
Glucose: directly through the aquatic animal gill and body surface makeup energy and nutrition; Enhancing body vigor and premunition are improved because of stress such as loss of appetite that multiple reason such as water quality deterioration or drug side effect causes, anorexia, refusing to eat, the unknown cause trip pools effectively.Detoxify, analyse poison, enhancing human body immunity power is accelerated body recovery, replenishes the required carbon source of body growth, enhances metabolism, and reduces the bait consumption, improves survival rate.
The beneficial effect that the present invention had: medicine of the present invention complements each other above-mentioned each composition organic assembling, can bring into play the function of each composition to greatest extent; Can external oral administration again; Prevent and treat aquatic animal at the symptoms of stress that draws in the net, occurs in the transportation, environmental catastrophe process; Improve the grazing rate of aquatic animal; Promote growth, improve the immunity of aquatic animal body greatly simultaneously, but also the harm of having avoided drug residue that human health is caused; Reasonable recipe of the present invention, preparation is simple, and with low cost, easy to use, the Application and Development curative effect is certain, and toxic and side effects is little, and applied range, and obvious application effect has vast market prospect.
The specific embodiment
Below in conjunction with preferred embodiment, to details are as follows according to the specific embodiment provided by the invention:
Embodiment 1: (every part by 1kg)
The raw material medicaments in part by weight of crossing 20～80 mesh sieves after pulverizing is counted proportioning take by weighing Semen Ziziphi Spinosae 5kg, Radix Et Caulis Acanthopanacis Senticosi 10kg, Fructus Schisandrae Chinensis 5kg, Radix Glycyrrhizae 5kg, starch 75kg, mixing and stirring is promptly processed this aquatic animal and is used anti-stress medicine then.
The various crude drug that adopt among the present invention are pharmaceutical grade.
Embodiment 2: (every part by 1kg)
The raw material medicaments in part by weight of crossing 20～80 mesh sieves after pulverizing is counted proportioning take by weighing Semen Ziziphi Spinosae 15kg; Radix Et Caulis Acanthopanacis Senticosi 30kg; Fructus Schisandrae Chinensis 15kg, Radix Glycyrrhizae 15kg, starch, zeolite powder, glucose be one or more any proportioning 25kg wherein; Mixing and stirring is promptly processed this aquatic animal and is used anti-stress medicine then.
The various crude drug that adopt among the present invention are pharmaceutical grade.
Embodiment 3: (every part by 1kg)
The raw material medicaments in part by weight of crossing 20～80 mesh sieves after pulverizing is counted proportioning take by weighing Semen Ziziphi Spinosae 10kg, Radix Et Caulis Acanthopanacis Senticosi 20kg, Fructus Schisandrae Chinensis 12kg, Radix Glycyrrhizae 12kg, starch 46kg, mixing and stirring is promptly processed this aquatic animal and is used anti-stress medicine then.
The various crude drug that adopt among the present invention are pharmaceutical grade.
The clinical practice experiment is given an example:
The Tianjin Hangu District is the Chinese prawn cultivation base; The breeding density here reaches 10～150,000/mu. and rice belongs to high-density breeding, because of changing the water inconvenience; After temperature raises to June; Onset peak arrives, and adds that water environment is quite abominable, and series reaction such as inappetence, the trip pool, anorexia, sickness rate increase appear in prawn.The raiser is culturing middle and late stage, in feedstuff, adds anti-stress medicine of the present invention (add 3～5 grams in the per kilogram feedstuff and feed, took every month 5～7 days) and liver and gall health and comes the liver protecting, improves the body constitution of aquatic animal, strengthens anti-stress ability.The Penaeus vannamei food of culturing in the breeding process in 7～JIUYUE is normal, and neighbour pond is not added the shrimp pond of anti-stress medicine of the present invention and compared, and feed coefficient reduces by 3%, finds phenomenons such as the trip pool, refusing to eat, obvious application effect.
Above-mentioned detailed description of this aquatic animal being carried out with anti-stress medicine and preparation method thereof with reference to embodiment; Be illustrative rather than determinate; Can enumerate out several embodiment according to institute's limited range; Therefore in the variation and the modification that do not break away under the general plotting of the present invention, should belong within protection scope of the present invention.
Claims (3)
1. anti-stress medicine is used in an aquatic animal, it is characterized in that being formed by following portions by weight proportion raw material medicine mixed preparing: 5～15 parts of Semen Ziziphi Spinosaes, 10～30 parts of Radix Et Caulis Acanthopanacis Senticosis, 5～15 parts of Fructus Schisandrae Chinensis, 5～15 parts in Radix Glycyrrhizae, 25～75 parts in carrier.
2. anti-stress medicine is used in aquatic animal according to claim 1, it is characterized in that said carrier is more than one in starch, zeolite powder, the glucose.
3. an aquatic animal according to claim 1 and 2 is characterized in that carrying out as follows with the method for preparing of anti-stress medicine:
Following various crude drug are pulverized 20～80 mesh sieves, took by weighing 5～15 parts of Semen Ziziphi Spinosaes by weight, 10～30 parts of Radix Et Caulis Acanthopanacis Senticosis, 5～15 parts of Fructus Schisandrae Chinensis, 5～15 parts in Radix Glycyrrhizae, 25～75 parts in carrier, uniform mixing.
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| CN201110185494A CN102309564A (en) | 2011-07-05 | 2011-07-05 | Anti-stress drug used for aquatic livestock and its preparation method |
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Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102894210A (en) * | 2012-08-27 | 2013-01-30 | 广东海大集团股份有限公司 | Anti-stress Chinese herbal medicine composite feedstuff additive specially used for penaeus vannamei |
| CN102987164A (en) * | 2012-12-26 | 2013-03-27 | 中国水产科学研究院淡水渔业研究中心 | Megalobrama amblycephala compound Chinese medicinal herb anti-stress preparation, and preparation method and use method thereof |
| CN103610778A (en) * | 2013-12-05 | 2014-03-05 | 山西省农业科学院畜牧兽医研究所 | Anti-chicken heat stress Chinese medicinal preparation and preparation method thereof |
| CN104666809A (en) * | 2013-11-28 | 2015-06-03 | 天津瑞贝特科技发展有限公司 | Traditional Chinese medicine composition with anti-stress effect and preparation method thereof |
| CN105012686A (en) * | 2015-08-18 | 2015-11-04 | 梧州市景泰养鳖专业合作社 | Medicinal preparation for treating stress-related diseases of Chinese soft-shelled turtles and preparing method thereof |
| CN105055857A (en) * | 2015-08-18 | 2015-11-18 | 梧州市景泰养鳖专业合作社 | Traditional Chinese medicine preparation for treating stress diseases of Chinese softshell turtles and preparation method of preparation |
| CN105533269A (en) * | 2015-12-17 | 2016-05-04 | 雷春生 | Preparation method of composite type green pollution-free anti-stress agent for aquaculture |
| CN106417125A (en) * | 2016-09-13 | 2017-02-22 | 中国水产科学研究院淡水渔业研究中心 | Method for improving acid stress resistance of procambarus clarkii |
| CN113598094A (en) * | 2021-08-09 | 2021-11-05 | 四川省农业科学院水产研究所(四川省水产研究所) | Breeding method for improving anti-stress response capability of fishes |
| CN116870091A (en) * | 2023-07-13 | 2023-10-13 | 华南农业大学 | Traditional Chinese medicine compound for resisting LPS stress of broiler chickens as well as preparation and application thereof |
-
2011
- 2011-07-05 CN CN201110185494A patent/CN102309564A/en active Pending
Cited By (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102894210A (en) * | 2012-08-27 | 2013-01-30 | 广东海大集团股份有限公司 | Anti-stress Chinese herbal medicine composite feedstuff additive specially used for penaeus vannamei |
| CN102987164A (en) * | 2012-12-26 | 2013-03-27 | 中国水产科学研究院淡水渔业研究中心 | Megalobrama amblycephala compound Chinese medicinal herb anti-stress preparation, and preparation method and use method thereof |
| CN102987164B (en) * | 2012-12-26 | 2014-05-28 | 中国水产科学研究院淡水渔业研究中心 | Megalobrama amblycephala compound Chinese medicinal herb anti-stress preparation, and preparation method and use method thereof |
| CN104666809A (en) * | 2013-11-28 | 2015-06-03 | 天津瑞贝特科技发展有限公司 | Traditional Chinese medicine composition with anti-stress effect and preparation method thereof |
| CN103610778A (en) * | 2013-12-05 | 2014-03-05 | 山西省农业科学院畜牧兽医研究所 | Anti-chicken heat stress Chinese medicinal preparation and preparation method thereof |
| CN103610778B (en) * | 2013-12-05 | 2015-07-15 | 山西省农业科学院畜牧兽医研究所 | Anti-chicken heat stress Chinese medicinal preparation and preparation method thereof |
| CN105055857B (en) * | 2015-08-18 | 2018-07-13 | 梧州市景泰养鳖专业合作社 | Treat the Chinese medicine preparation and preparation method thereof of Shelled Turtle Trionyx Sinensis stress disease |
| CN105012686A (en) * | 2015-08-18 | 2015-11-04 | 梧州市景泰养鳖专业合作社 | Medicinal preparation for treating stress-related diseases of Chinese soft-shelled turtles and preparing method thereof |
| CN105055857A (en) * | 2015-08-18 | 2015-11-18 | 梧州市景泰养鳖专业合作社 | Traditional Chinese medicine preparation for treating stress diseases of Chinese softshell turtles and preparation method of preparation |
| CN105012686B (en) * | 2015-08-18 | 2018-08-31 | 梧州市景泰养鳖专业合作社 | A kind of pharmaceutical preparation and preparation method thereof for treating Shelled Turtle Trionyx Sinensis stress disease |
| CN105533269A (en) * | 2015-12-17 | 2016-05-04 | 雷春生 | Preparation method of composite type green pollution-free anti-stress agent for aquaculture |
| CN106417125A (en) * | 2016-09-13 | 2017-02-22 | 中国水产科学研究院淡水渔业研究中心 | Method for improving acid stress resistance of procambarus clarkii |
| CN113598094A (en) * | 2021-08-09 | 2021-11-05 | 四川省农业科学院水产研究所(四川省水产研究所) | Breeding method for improving anti-stress response capability of fishes |
| CN113598094B (en) * | 2021-08-09 | 2022-12-06 | 四川省农业科学院水产研究所(四川省水产研究所) | Breeding method for improving anti-stress response capability of fishes |
| CN116870091A (en) * | 2023-07-13 | 2023-10-13 | 华南农业大学 | Traditional Chinese medicine compound for resisting LPS stress of broiler chickens as well as preparation and application thereof |
| CN116870091B (en) * | 2023-07-13 | 2024-04-12 | 华南农业大学 | Traditional Chinese medicine compound for resisting LPS stress of broiler chickens as well as preparation and application thereof |
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Application publication date: 20120111 |