CN112544796A - Compound feed for preventing and treating liver and gall syndrome of grass carps and preparation method thereof - Google Patents
Compound feed for preventing and treating liver and gall syndrome of grass carps and preparation method thereof Download PDFInfo
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- A23K20/10—Organic substances
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- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/20—Inorganic substances, e.g. oligoelements
- A23K20/24—Compounds of alkaline earth metals, e.g. magnesium
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/19—Acanthaceae (Acanthus family)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
- A61K36/315—Isatis, e.g. Dyer's woad
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/35—Caprifoliaceae (Honeysuckle family)
- A61K36/355—Lonicera (honeysuckle)
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/539—Scutellaria (skullcap)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/708—Rheum (rhubarb)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/756—Phellodendron, e.g. corktree
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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Abstract
A compound feed for preventing and treating liver and gall syndrome of grass carp and a preparation method thereof comprise the following raw materials in parts by weight: high protein soybean meal: 25-45 parts; flour: 15-30 parts; instant noodle dregs: 3-6 parts; vinasse: 3-8 parts; the compound Chinese herbal medicine comprises the following components: 2-5 parts; chicken powder: 2-4 parts; soybean oil: 1-3 parts; fine stone powder: 0.8-1.5 parts; choline chloride: 0.02-0.05 part; lysine hydrochloride salt: 0.1-0.3 part; methionine: 0.1-0.3 part; threonine: 0.1-0.3 part; VC grease: 0.1-0.3 part; calcium dihydrogen phosphate: 8-15 parts; 1-5 parts of multi-mineral premix for fish and 0.5-2 parts of multi-vitamin premix for fish. The feed can prevent and treat liver and gall syndrome of the grass carp, improve survival rate, increase growth speed and reduce feed coefficient.
Description
Technical Field
The invention relates to the technical field of feed production, in particular to a compound feed for preventing and treating liver and gall syndrome of grass carp and a preparation method thereof.
Background
The reason for inducing the liver and gall syndrome of the grass carp is that the weather suddenly changes greatly, the problems of insufficient oxygen supply and excessive feeding are caused, the water body is deteriorated, the alga community is unbalanced, harmful substances such as nitrite and ammonia nitrogen in the water body are increased, the liver and gall load of the grass carp body is continuously increased, the physique of the grass carp is reduced, and the liver and gall syndrome is finally induced. In addition, after the water environment is changed, a large amount of parasites and harmful bacteria in the water can be propagated, so that enteritis, gill rot and the like of the grass carps can be caused. Therefore, the liver and gall bladder of fish can be damaged due to deterioration of water body environment, excessive feeding, drug abuse, feed deterioration, lack of trace elements and the like, so that hepatobiliary syndrome occurs, and the occurrence of hepatobiliary syndrome brings great negative effects on aquaculture. There are also ways of adding antibiotics, such as sulfonamides, to feed, which has proven to be one of the causes of liver damage in fish.
Disclosure of Invention
The invention aims to solve the problems and provides a compound feed for preventing and treating liver and gall syndrome of grass carps and a preparation method thereof.
The technical scheme adopted by the invention is as follows:
a compound feed for preventing and treating liver and gall syndrome of grass carps comprises the following raw materials in parts by weight:
high protein soybean meal: 25-45 parts; flour: 15-30 parts; instant noodle dregs: 3-6 parts; vinasse: 3-8 parts; the compound Chinese herbal medicine comprises the following components: 2-5 parts; chicken powder: 2-4 parts; soybean oil: 1-3 parts; fine stone powder: 0.8-1.5 parts; choline chloride: 0.02-0.05 part; lysine hydrochloride salt: 0.1-0.3 part; methionine: 0.1-0.3 part; threonine: 0.1-0.3 part; VC grease: 0.1-0.3 part; calcium dihydrogen phosphate: 8-15 parts; 1-5 parts of multi-mineral premix for fish and 0.5-2 parts of multi-vitamin premix for fish.
The compound Chinese herbal medicine comprises the components of liquorice, rhubarb, honeysuckle, isatis root, phellodendron and scutellaria.
The compound Chinese herbal medicine comprises the following components in parts by weight of 2:2:2: 2: 1: 1.
the vitamin premix comprises vitamin A, vitamin D3, vitamin k3, vitamin E, B, vitamins, nicotinamide, calcium pantothenate, folic acid, biotin and inositol;
the vitamin premix comprises the components of vitamin A, vitamin D3, vitamin k3 and vitamin E; the weight portion ratio of the B group vitamin to the nicotinamide to the calcium pantothenate to the folic acid to the biotin to the inositol is 10-15:15-25:15-25:20-30:5-10:5-10:5-10:5-15:5-10: 1-5.
The mineral premix comprises ferric sulfate, copper sulfate, manganese sulfate, zinc sulfate, calcium iodate and sodium selenite.
The mineral premix comprises the following components, by weight, 15-30 parts of ferric sulfate, 20-40 parts of copper sulfate, manganese sulfate, zinc sulfate, calcium iodate and sodium selenite, 15-20 parts of 5-10 parts of 1-5 parts of sodium selenite.
A preparation method of a compound feed for preventing and treating liver and gall syndrome of grass carps comprises the following steps:
(1) weighing the raw materials according to the proportion;
(2) mixing twice and crushing twice according to the production process requirements, performing primary crushing after the primary mixing, wherein the crushing fineness is that 85 percent of the mixture passes through 65 meshes, adding choline chloride, lysine hydrochloride, methionine, threonine and calcium dihydrogen phosphate into a mixer to perform secondary mixing, performing secondary crushing with the fineness of 80 meshes and 97 percent of the mixture passes through, blending, and performing puffing and granulation.
The invention has the beneficial effects that: the feed can prevent and treat liver and gall syndrome of the grass carp, improve survival rate, increase growth speed and reduce feed coefficient.
Detailed Description
A compound feed for preventing and treating liver and gall syndrome of grass carps comprises the following raw materials in parts by weight:
high protein soybean meal: 25-45 parts; flour: 15-30 parts; instant noodle dregs: 3-6 parts; vinasse: 3-8 parts; the compound Chinese herbal medicine comprises the following components: 2-5 parts; chicken powder: 2-4 parts; soybean oil: 1-3 parts; fine stone powder: 0.8-1.5 parts; choline chloride: 0.02-0.05 part; lysine hydrochloride salt: 0.1-0.3 part; methionine: 0.1-0.3 part; threonine: 0.1-0.3 part; VC grease: 0.1-0.3 part; calcium dihydrogen phosphate: 8-15 parts; 1-5 parts of multi-mineral premix for fish and 0.5-2 parts of multi-vitamin premix for fish.
The compound Chinese herbal medicine comprises the components of liquorice, rhubarb, honeysuckle, isatis root, phellodendron and scutellaria.
The compound Chinese herbal medicine comprises the following components in parts by weight of 2:2:2: 2: 1: 1.
the vitamin premix comprises the components of 10-15:15-25:15-25:20-30:5-10:5-10:5-10:5-15:5-10:1-5 in parts by weight.
The mineral premix comprises the following components, by weight, 15-30 parts of ferric sulfate, 20-40 parts of copper sulfate, manganese sulfate, zinc sulfate, calcium iodate and sodium selenite, 15-20 parts of 5-10 parts of 1-5 parts of sodium selenite.
A preparation method of a compound feed for preventing and treating liver and gall syndrome of grass carps comprises the following steps:
(1) weighing the raw materials according to the proportion;
(2) mixing twice and crushing twice according to the production process requirements, performing primary crushing after the primary mixing, wherein the crushing fineness is that 85 percent of the mixture passes through 65 meshes, adding choline chloride, lysine hydrochloride, methionine, threonine and calcium dihydrogen phosphate into a mixer to perform secondary mixing, performing secondary crushing with the fineness of 80 meshes and 97 percent of the mixture passes through, blending, and performing puffing and granulation.
The present invention will be described in detail with reference to specific examples.
Example 1
A compound feed for preventing and treating liver and gall syndrome of grass carps comprises the following raw materials in parts by weight:
high protein soybean meal: 25 parts of (1); flour: 15 parts of (1); instant noodle dregs: 3 parts of a mixture; vinasse: 3 parts of a mixture; the compound Chinese herbal medicine comprises the following components: 2 parts of (1); chicken powder: 2 parts of (1); soybean oil: 1 part; fine stone powder: 0.8 part; choline chloride: 0.02 part; lysine hydrochloride salt: 0.1 part; methionine: 0.1 part; threonine: 0.1 part; VC grease: 0.1 part; calcium dihydrogen phosphate: 8 parts of a mixture; 1 part of multi-mineral premix for fish and 0.5 part of multi-vitamin premix for fish.
The compound Chinese herbal medicine comprises the following components in parts by weight of 2:2:2: 2: 1: 1.
the vitamin premix comprises the components of vitamin A, vitamin D3, vitamin k3, vitamin E, B, vitamin E, nicotinamide, calcium pantothenate, folic acid, biotin and inositol in parts by weight of 10:15:15:20:5:5:5:5:5: 1.
The mineral premix comprises the components of ferric sulfate, copper sulfate, manganese sulfate, zinc sulfate, calcium iodate and sodium selenite in parts by weight of 15:20:15:15:5: 1.
A preparation method of a compound feed for preventing and treating liver and gall syndrome of grass carps comprises the following steps:
(1) weighing the raw materials according to the proportion;
(2) mixing twice and crushing twice according to the production process requirements, performing primary crushing after the primary mixing, wherein the crushing fineness is that 85 percent of the mixture passes through 65 meshes, adding choline chloride, lysine hydrochloride, methionine, threonine and calcium dihydrogen phosphate into a mixer to perform secondary mixing, performing secondary crushing with the fineness of 80 meshes and 97 percent of the mixture passes through, blending, and performing puffing and granulation.
Example 2
A compound feed for preventing and treating liver and gall syndrome of grass carps comprises the following raw materials in parts by weight:
high protein soybean meal: 45 parts of (1); flour: 30 parts of (1); instant noodle dregs: 6 parts of (1); vinasse: 8 parts of a mixture; the compound Chinese herbal medicine comprises the following components: 5 parts of a mixture; chicken powder: 4 parts of a mixture; soybean oil: 3 parts of a mixture; fine stone powder: 1.5 parts; choline chloride: 0.05 part; lysine hydrochloride salt: 0.3 part; methionine: 0.3 part; threonine: 0.3 part; VC grease: 0.3 part; calcium dihydrogen phosphate: 15 parts of (1); 5 parts of multi-mineral premix for fish and 2 parts of multi-vitamin premix for fish.
The compound Chinese herbal medicine comprises the following components in parts by weight of 2:2:2: 2: 1: 1.
the vitamin premix comprises the components of vitamin A, vitamin D3, vitamin k3, vitamin E, B, vitamin E, nicotinamide, calcium pantothenate, folic acid, biotin and inositol in a weight ratio of 3:5:5:6:2:2:2:3:2: 1.
The mineral premix comprises the components of ferric sulfate, copper sulfate, manganese sulfate, zinc sulfate, calcium iodate and sodium selenite in parts by weight of 6:8:4:4:2: 1.
A preparation method of a compound feed for preventing and treating liver and gall syndrome of grass carps comprises the following steps:
(1) weighing the raw materials according to the proportion;
(2) mixing twice and crushing twice according to the production process requirements, performing primary crushing after the primary mixing, wherein the crushing fineness is that 85 percent of the mixture passes through 65 meshes, adding choline chloride, lysine hydrochloride, methionine, threonine and calcium dihydrogen phosphate into a mixer to perform secondary mixing, performing secondary crushing with the fineness of 80 meshes and 97 percent of the mixture passes through, blending, and performing puffing and granulation.
Example 3
A compound feed for preventing and treating liver and gall syndrome of grass carps comprises the following raw materials in parts by weight:
high protein soybean meal: 35 parts of (B); flour: 20 parts of (1); instant noodle dregs: 4 parts of a mixture; vinasse: 5 parts of a mixture; the compound Chinese herbal medicine comprises the following components: 4 parts of a mixture; chicken powder: 3 parts of a mixture; soybean oil: 2 parts of (1); fine stone powder: 1 part; choline chloride: 0.03 part; lysine hydrochloride salt: 0.2 part; methionine: 0.2 part; threonine: 0.2 part; VC grease: 0.2 part; calcium dihydrogen phosphate: 10 parts of (A); 3 parts of multi-mineral premix for fish and 1 part of multi-vitamin premix for fish.
The compound Chinese herbal medicine comprises the following components in parts by weight of 2:2:2: 2: 1: 1.
the vitamin premix comprises the components of vitamin A, vitamin D3, vitamin k3, vitamin E, B, vitamin E, nicotinamide, calcium pantothenate, folic acid, biotin and inositol in parts by weight of 12:18:20: 8:8:8:10:8: 4.
The mineral premix comprises the following components, by weight, 15-30 parts of ferric sulfate, 20-40 parts of copper sulfate, manganese sulfate, zinc sulfate, calcium iodate and sodium selenite, 15-20 parts of 5-10 parts of 1-5 parts of sodium selenite.
A preparation method of a compound feed for preventing and treating liver and gall syndrome of grass carps comprises the following steps:
(1) weighing the raw materials according to the proportion;
(2) mixing twice and crushing twice according to the production process requirements, performing primary crushing after the primary mixing, wherein the crushing fineness is that 85 percent of the mixture passes through 65 meshes, adding choline chloride, lysine hydrochloride, methionine, threonine and calcium dihydrogen phosphate into a mixer to perform secondary mixing, performing secondary crushing with the fineness of 80 meshes and 97 percent of the mixture passes through, blending, and performing puffing and granulation.
In order to verify the control effect of the feed, the following experiments prove that:
in a grass carp culture pond, about 30g of 1200 tails of grass carps with sound physique and almost consistent specifications are selected and randomly divided into four groups, namely a control group, an experimental group 1, an experimental group 2 and an experimental group 3, each group is repeated for 3, 100 tails of each group of grass carps are fed with grass carp feed sold in the market, the experimental group 1 feeds the formula feed in the embodiment 1 of the invention, the experimental group 2 feeds the formula feed in the embodiment 2 of the invention, the experimental group 3 feeds the formula feed in the embodiment 3 of the invention, the grass carps are continuously fed for 100 days, the grass carps are fed for 3 times every day, the grass carps are weighed after the experiment begins and ends, and the weight gain rate and the survival rate are calculated, and the results are shown in the following table.
| Mantissa | Initial average weight (g) | Average weight of powder (g) | Weight gainPercentage (%) | Incidence (%) | |
| Control group | 300 | 30.21 | 96.55 | 219.60 | 3.2 |
| Experimental group 1 | 300 | 30.33 | 114.45 | 277.35 | 1.3 |
| Experimental group 2 | 300 | 30.65 | 121.43 | 296.18 | 1.1 |
| Experimental group 3 | 300 | 30.24 | 119.89 | 296.46 | 1.2 |
As can be seen from the table above, compared with the control group, the weight gain rate of the experimental group is obviously higher, and the survival rate is higher, so that the feed disclosed by the invention has better food calling property and immunity.
The embodiments of the present invention have been described in detail, but the description is only for the preferred embodiments of the present invention and should not be construed as limiting the scope of the present invention. All equivalent changes and modifications made within the scope of the present invention shall fall within the scope of the present invention.
Claims (8)
1. The compound feed for preventing and treating liver and gall syndrome of the grass carps is characterized by comprising the following raw materials in parts by weight:
high protein soybean meal: 25-45 parts; flour: 15-30 parts; instant noodle dregs: 3-6 parts; vinasse: 3-8 parts; the compound Chinese herbal medicine comprises the following components: 2-5 parts; chicken powder: 2-4 parts; soybean oil: 1-3 parts; fine stone powder: 0.8-1.5 parts; choline chloride: 0.02-0.05 part; lysine hydrochloride salt: 0.1-0.3 part; methionine: 0.1-0.3 part; threonine: 0.1-0.3 part; VC grease: 0.1-0.3 part; calcium dihydrogen phosphate: 8-15 parts; 1-5 parts of multi-mineral premix for fish and 0.5-2 parts of multi-vitamin premix for fish.
2. The compound feed for preventing and treating liver and gall syndrome of grass carp as claimed in claim 1, wherein the compound Chinese herbal medicine components are licorice, rhubarb, honeysuckle, isatis root, phellodendron bark and scutellaria baicalensis.
3. The compound feed for preventing and treating liver and gall syndrome of grass carp as claimed in claim 2, wherein the compound Chinese herbal medicine comprises licorice, rhubarb, honeysuckle, isatis root, phellodendron bark and scutellaria baicalensis in a weight ratio of 2:2:2: 2: 1: 1.
4. the compound feed for preventing and treating liver and gall syndrome of grass carp as claimed in claim 1, wherein said vitamin premix comprises vitamin A, vitamin D3, vitamin k3, vitamin E, B, vitamins of the vitamin group, nicotinamide, calcium pantothenate, folic acid, biotin and inositol.
5. The compound feed for preventing and treating liver and gall syndrome of grass carp as claimed in claim 4, wherein said vitamin premix comprises vitamin A, vitamin D3, vitamin k3, vitamin E; the weight portion ratio of the B group vitamin to the nicotinamide to the calcium pantothenate to the folic acid to the biotin to the inositol is 10-15:15-25:15-25:20-30:5-10:5-10:5-10:5-15:5-10: 1-5.
6. The compound feed for preventing and treating liver and gall syndrome of grass carp as claimed in claim 1, wherein the mineral premix comprises ferric sulfate, copper sulfate, manganese sulfate, zinc sulfate, calcium iodate and sodium selenite.
7. The compound feed for preventing and treating liver and gall syndrome of grass carp as claimed in claim 6, wherein the weight portion ratio of each component of the mineral premix, namely ferric sulfate, copper sulfate, manganese sulfate, zinc sulfate, calcium iodate and sodium selenite, is 15-30:20-40:15-20:15-20:5-10: 1-5.
8. A preparation method of a compound feed for preventing and treating liver and gall syndrome of grass carps is characterized by comprising the following steps:
(1) weighing the raw materials according to the proportion;
(2) mixing twice and crushing twice according to the production process requirements, performing primary crushing after the primary mixing, wherein the crushing fineness is that 85 percent of the mixture passes through 65 meshes, adding choline chloride, lysine hydrochloride, methionine, threonine and calcium dihydrogen phosphate into a mixer to perform secondary mixing, performing secondary crushing with the fineness of 80 meshes and 97 percent of the mixture passes through, blending, and performing puffing and granulation.
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| CN202011538244.7A CN112544796A (en) | 2020-12-23 | 2020-12-23 | Compound feed for preventing and treating liver and gall syndrome of grass carps and preparation method thereof |
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| CN202011538244.7A CN112544796A (en) | 2020-12-23 | 2020-12-23 | Compound feed for preventing and treating liver and gall syndrome of grass carps and preparation method thereof |
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101590140A (en) * | 2008-05-30 | 2009-12-02 | 北京大北农动物保健科技有限责任公司 | A kind of compound medicament composition of preventing and treating liver and gall syndrome of fish and preparation method thereof |
| CN103316132A (en) * | 2013-06-03 | 2013-09-25 | 山西农业大学 | Compound medicine for preventing and treating fish liver-gall syndrome |
| CN104855708A (en) * | 2015-04-30 | 2015-08-26 | 宁夏大北农科技实业有限公司 | Feed for preventing and treating liver and gall syndrome of grass carps and preparation method therefor |
| CN109645254A (en) * | 2018-12-27 | 2019-04-19 | 天津现代天骄水产饲料股份有限公司 | A kind of Micropterus salmonoides puffing material |
-
2020
- 2020-12-23 CN CN202011538244.7A patent/CN112544796A/en not_active Withdrawn
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101590140A (en) * | 2008-05-30 | 2009-12-02 | 北京大北农动物保健科技有限责任公司 | A kind of compound medicament composition of preventing and treating liver and gall syndrome of fish and preparation method thereof |
| CN103316132A (en) * | 2013-06-03 | 2013-09-25 | 山西农业大学 | Compound medicine for preventing and treating fish liver-gall syndrome |
| CN104855708A (en) * | 2015-04-30 | 2015-08-26 | 宁夏大北农科技实业有限公司 | Feed for preventing and treating liver and gall syndrome of grass carps and preparation method therefor |
| CN109645254A (en) * | 2018-12-27 | 2019-04-19 | 天津现代天骄水产饲料股份有限公司 | A kind of Micropterus salmonoides puffing material |
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Application publication date: 20210326 |