CN102934740B - Composite immunopotentiator for garrupa - Google Patents
Composite immunopotentiator for garrupa Download PDFInfo
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- CN102934740B CN102934740B CN 201210481496 CN201210481496A CN102934740B CN 102934740 B CN102934740 B CN 102934740B CN 201210481496 CN201210481496 CN 201210481496 CN 201210481496 A CN201210481496 A CN 201210481496A CN 102934740 B CN102934740 B CN 102934740B
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- parts
- powder
- immunopotentiator
- garrupa
- feed
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- 239000002131 composite material Substances 0.000 title claims abstract description 14
- 230000000091 immunopotentiator Effects 0.000 title claims abstract description 14
- 239000000843 powder Substances 0.000 claims abstract description 27
- 241000132012 Atractylodes Species 0.000 claims abstract description 9
- 240000001432 Calendula officinalis Species 0.000 claims abstract description 9
- 235000009917 Crataegus X brevipes Nutrition 0.000 claims abstract description 9
- 235000013204 Crataegus X haemacarpa Nutrition 0.000 claims abstract description 9
- 235000009685 Crataegus X maligna Nutrition 0.000 claims abstract description 9
- 235000009444 Crataegus X rubrocarnea Nutrition 0.000 claims abstract description 9
- 235000009486 Crataegus bullatus Nutrition 0.000 claims abstract description 9
- 235000017181 Crataegus chrysocarpa Nutrition 0.000 claims abstract description 9
- 235000009682 Crataegus limnophila Nutrition 0.000 claims abstract description 9
- 235000004423 Crataegus monogyna Nutrition 0.000 claims abstract description 9
- 235000002313 Crataegus paludosa Nutrition 0.000 claims abstract description 9
- 235000009840 Crataegus x incaedua Nutrition 0.000 claims abstract description 9
- 235000009811 Momordica charantia Nutrition 0.000 claims abstract description 9
- 240000000171 Crataegus monogyna Species 0.000 claims abstract 3
- 241001417495 Serranidae Species 0.000 claims description 24
- 235000005881 Calendula officinalis Nutrition 0.000 claims description 8
- 241000208688 Eucommia Species 0.000 claims description 8
- 244000302512 Momordica charantia Species 0.000 claims description 8
- 235000009812 Momordica cochinchinensis Nutrition 0.000 claims description 8
- 235000018365 Momordica dioica Nutrition 0.000 claims description 8
- 239000012744 reinforcing agent Substances 0.000 claims description 8
- 239000009636 Huang Qi Substances 0.000 claims description 4
- 241000411851 herbal medicine Species 0.000 abstract description 9
- 230000036039 immunity Effects 0.000 abstract description 7
- 201000010099 disease Diseases 0.000 abstract description 6
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract description 6
- 238000000034 method Methods 0.000 abstract description 5
- 230000004083 survival effect Effects 0.000 abstract description 5
- 230000000694 effects Effects 0.000 abstract description 4
- 239000003674 animal food additive Substances 0.000 abstract description 3
- 239000002994 raw material Substances 0.000 abstract description 3
- 230000003115 biocidal effect Effects 0.000 abstract description 2
- 238000004519 manufacturing process Methods 0.000 abstract description 2
- 235000019629 palatability Nutrition 0.000 abstract description 2
- 244000078912 Trichosanthes cucumerina Species 0.000 abstract 1
- 235000008322 Trichosanthes cucumerina Nutrition 0.000 abstract 1
- 229940107666 astragalus root Drugs 0.000 abstract 1
- 239000004615 ingredient Substances 0.000 abstract 1
- 230000003014 reinforcing effect Effects 0.000 abstract 1
- 231100000331 toxic Toxicity 0.000 abstract 1
- 230000002588 toxic effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 description 9
- 241001092040 Crataegus Species 0.000 description 6
- 241000545442 Radix Species 0.000 description 4
- 241000357439 Epinephelus Species 0.000 description 3
- 241000607479 Yersinia pestis Species 0.000 description 3
- 241000251468 Actinopterygii Species 0.000 description 2
- 230000015556 catabolic process Effects 0.000 description 2
- 238000006731 degradation reaction Methods 0.000 description 2
- 206010067482 No adverse event Diseases 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 239000003653 coastal water Substances 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000003031 feeding effect Effects 0.000 description 1
- 235000021393 food security Nutrition 0.000 description 1
- 230000009545 invasion Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 235000013372 meat Nutrition 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 235000008935 nutritious Nutrition 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 230000001902 propagating effect Effects 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Fodder In General (AREA)
Abstract
The invention discloses a composite immunopotentiator for garrupa and belongs to the technical field of feed additives. The composite immunopotentiator is characterized by consisting of the following ingredients in parts by weight: 5-15 parts of potmarigold calendula rachis powder, 10-20 parts of folium cortex eucommiae powder, 5-10 parts of bitter gourd powder, 12-18 parts of radix bupleuri, 12-18 parts of astragalus root, 5-10 parts of dried old orange peel, 5-10 parts of bighead atractylodes rhizome, 12-18 parts of hawthorn and 5-10 parts of acanthopanax. The composite immunopotentiator disclosed by the invention is added in a garrupa mixed feed as a feed additive so as to completely replace antibiotic; the natural Chinese herbal medicine can be used for effectively reinforcing the immunity of the organism of the garrupa, improving the resistance on diseases and improving the rate of survival; the composite immunopotentiator is free from a toxic side effect and an untoward effect and is free from unfavorable effect on palatability of the feed; and the raw material source of the composite immunopotentiator disclosed by the invention is stable, the cost is low and the production technique is simple.
Description
Technical field
The invention belongs to field of feed additive technology, be specifically related to a kind of complex immunopotentiator for grouper.
background technology
Epinephelus fin section, Epinephelus are water warm coastal waters bottom rare fish classes.Meat is fertile fresh and tender, nutritious, deeply is subject to people's praise, and first-class delicacies is regarded as in live fish transportation and sales Hongkong and Macro market, and supply falls short of demand.It is expensive, and economic worth is high.In recent years, along with the development of culture fishery, grouper propagate the concern that more and more is subject to people artificially.
Along with the development of propagating industry artificially of grouper, its disease and pest also increases gradually, often some disease and pests can occur, and causes the immunity degradation of grouper, the phenomenon that the grouper immunity degradation is even dead occurs.Therefore, how to improve the immunity of grouper body, the effectively invasion of resist the disease, reduce morbidity and the death rate, becomes the point of penetration of people's prevention and treatment grouper disease and pest.Research is indicated, Chinese herbal medicine has the effect of regulating body health, strengthening immunity of organisms, and Chinese herbal medicine is various in style, the property of medicine is various, cheap, aboundresources, adopt Chinese herbal medicine to make immunopotentiator and not only contribute to improve immunity of organisms, and, because Chinese herbal medicine belongs to natural materials, pollute few, meet the requirement of green fishery, be conducive to the requirement of people to food security.
Summary of the invention
For problems of the prior art, the object of the invention is providing a kind of complex immunopotentiator for grouper.
The present invention is realized by the following technical programs:
Described complex immunopotentiator for grouper is characterized in that this composite immune reinforcing agent is comprised of the component of following parts by weight: pot marigold scape powder 5-15 part, Eucommia Leaf Powder 10-20 part, balsam pear powder 5-10 part, radix bupleuri 12-18 part, Radix Astragali 12-18 part, dried orange peel 5-10 part, bighead atractylodes rhizome 5-10 part, hawthorn 12-18 part, wilsonii 5-10 part.
Described complex immunopotentiator for grouper is characterized in that being comprised of the component of following parts by weight: pot marigold scape powder 10-15 part, Eucommia Leaf Powder 10-15 part, balsam pear powder 6-8 part, radix bupleuri 12-15 part, Radix Astragali 12-15 part, dried orange peel 6-8 part, bighead atractylodes rhizome 6-8 part, hawthorn 12-15 part, wilsonii 6-8 part.
With existing preparation, compare, the present invention has the following advantages:
(1) as feed addictive, in grouper compound feed, use, in order to replace antibiotic;
(2) effectively strengthen the immunity of organisms of grouper, improve the resistance to disease, improve survival rate;
(3) have no side effect and bad reaction, have no adverse effects for the palatability of feed;
(4) the raw materials used steady sources of the present invention, cheap, production technology is simple.
The specific embodiment
By following specific embodiment, the invention will be further described.
Embodiment 1
Get 5 parts, pot marigold scape powder, 20 parts of Eucommia Leaf Powders, 5 parts of balsam pear powders, 12 parts of radix bupleuri, 18 parts of the Radixs Astragali, 10 parts of dried orange peels, 5 parts of the bighead atractylodes rhizomes, 15 parts of hawthorn, 10 parts of wilsoniis, adopt routine techniques to grind to form fine powder the said herbal medicine composition, cross 120 mesh sieves, then mix in mixer and be composite immune reinforcing agent of the present invention, the amount of adding in the grouper mixed fodder is 0.1%.
Embodiment 2
Get 10 parts, pot marigold scape powder, 15 parts of Eucommia Leaf Powders, 8 parts of balsam pear powders, 15 parts of radix bupleuri, 15 parts of the Radixs Astragali, 8 parts of dried orange peels, 10 parts of the bighead atractylodes rhizomes, 12 parts of hawthorn, 7 parts of wilsoniis, adopt routine techniques to grind to form fine powder the said herbal medicine composition, cross 120 mesh sieves, then mix in mixer and be composite immune reinforcing agent of the present invention, the amount of adding in the grouper mixed fodder is 0.1%.
Embodiment 3
Get 15 parts, pot marigold scape powder, 13 parts of Eucommia Leaf Powders, 6 parts of balsam pear powders, 18 parts of radix bupleuri, 13 parts of the Radixs Astragali, 9 parts of dried orange peels, 6 parts of the bighead atractylodes rhizomes, 14 parts of hawthorn, 6 parts of wilsoniis, adopt routine techniques to grind to form fine powder the said herbal medicine composition, cross 120 mesh sieves, then mix in mixer and be composite immune reinforcing agent of the present invention, the amount of adding in the grouper mixed fodder is 0.15%.
Embodiment 4
Get 9 parts, pot marigold scape powder, 18 parts of Eucommia Leaf Powders, 10 parts of balsam pear powders, 16 parts of radix bupleuri, 12 parts of the Radixs Astragali, 6 parts of dried orange peels, 8 parts of the bighead atractylodes rhizomes, 13 parts of hawthorn, 8 parts of wilsoniis, adopt routine techniques to grind to form fine powder the said herbal medicine composition, cross 120 mesh sieves, then mix in mixer and be composite immune reinforcing agent of the present invention, the amount of adding in the grouper mixed fodder is 0.2%.
The composite immune reinforcing agent of making according to the composition of raw materials in above-described embodiment 1-4, add in the grouper mixed fodder grouper 11 months fed to, and feeding effect is in Table 1.
Table 1 grouper cage culture experimental result (raising 11 months)
| ? | Control group | Embodiment 1 | Embodiment 2 | Embodiment 3 | Embodiment 4 |
| Net cage number (only) | 50 | 50 | 50 | 50 | 50 |
| The mean feed | 1.59 | 1.38 | 1.40 | 1.35 | 1.36 |
| Feed coefficient reduces (%) | ? | 13.2 | 11.9 | 15.1 | 14.5 |
| Average survival | 78% | 87% | 89% | 86% | 92% |
| Survival rate improves (%) | ? | 11.5 | 14.1 | 10.3 | 17.9 |
Experimental result shows: in the cycle of grouper cage culture, use this composite immune reinforcing agent as grouper mixed fodder additive, epinephelus feed coefficient ratio control group has reduced respectively 13.2%, 11.9%, 15.1% and 14.5%; Survival rate has improved respectively 11.5%, 14.1%, 10.3% and 17.9%.
Claims (2)
1. complex immunopotentiator for grouper, is characterized in that this composite immune reinforcing agent is comprised of the component of following parts by weight: pot marigold scape powder 5-15 part, Eucommia Leaf Powder 10-20 part, balsam pear powder 5-10 part, radix bupleuri 12-18 part, Radix Astragali 12-18 part, dried orange peel 5-10 part, bighead atractylodes rhizome 5-10 part, hawthorn 12-18 part, wilsonii 5-10 part.
2. complex immunopotentiator for grouper according to claim 1, is characterized in that being comprised of the component of following parts by weight: pot marigold scape powder 10-15 part, Eucommia Leaf Powder 10-15 part, balsam pear powder 6-8 part, radix bupleuri 12-15 part, Radix Astragali 12-15 part, dried orange peel 6-8 part, bighead atractylodes rhizome 6-8 part, hawthorn 12-15 part, wilsonii 6-8 part.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201210481496 CN102934740B (en) | 2012-11-23 | 2012-11-23 | Composite immunopotentiator for garrupa |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201210481496 CN102934740B (en) | 2012-11-23 | 2012-11-23 | Composite immunopotentiator for garrupa |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102934740A CN102934740A (en) | 2013-02-20 |
| CN102934740B true CN102934740B (en) | 2013-12-18 |
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| CN 201210481496 Expired - Fee Related CN102934740B (en) | 2012-11-23 | 2012-11-23 | Composite immunopotentiator for garrupa |
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Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103300258B (en) * | 2013-07-11 | 2014-05-07 | 曾勇 | Special feed additive for fattened cattle |
| CN104095153B (en) * | 2014-04-23 | 2016-01-27 | 浙江省海洋开发研究院 | A kind of red grouper special immune reinforcing agent |
| CN104095154B (en) * | 2014-04-23 | 2016-04-20 | 浙江省海洋开发研究院 | A kind of Cynoglossus semilaevis special immune reinforcing agent |
| CN104273377A (en) * | 2014-09-29 | 2015-01-14 | 浙江海洋学院 | Immunopotentiator for siganidae |
| CN104938869B (en) * | 2015-07-23 | 2018-07-17 | 上海海洋大学 | A kind of innate immunity reinforcing agent that protection grouper larvae is encroached on from nervous necrosis virus |
| CN105146077A (en) * | 2015-08-05 | 2015-12-16 | 贾红琴 | Chinese herbal medicine additive for aquaculture and application thereof |
| CN105724766A (en) * | 2016-02-28 | 2016-07-06 | 山东新希望六和集团有限公司 | Additive of grouper feed and preparation method of additive |
| CN106135081A (en) * | 2016-06-22 | 2016-11-23 | 温州雏鹰科技有限公司 | A kind of intensive culture method of cabrilla |
| CN106540157A (en) * | 2016-10-20 | 2017-03-29 | 集美大学 | A kind of cabrilla composite Chinese herbal immunostimulant |
| CN108669382B (en) * | 2018-08-06 | 2021-11-09 | 华南师范大学 | Application of bupleurum extract as feed additive for grouper |
| CN117322559B (en) * | 2023-09-28 | 2024-09-13 | 广东粤猪宝农牧科技有限公司 | Disease-resistant growth-promoting feed additive for sea fish and preparation method thereof |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
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| JP2005269913A (en) * | 2004-03-23 | 2005-10-06 | Daicho Kikaku:Kk | Fish feed additive, and fish feed |
| CN101406262B (en) * | 2008-11-17 | 2011-07-20 | 莆田市生物工程研究所 | Ecological type compound feed for juvenile Centropristis striata |
| CN101480436B (en) * | 2008-11-19 | 2011-05-25 | 广东海洋大学 | Compound Chinese herbal medicine immunopotentiator for grouper |
| KR101060312B1 (en) * | 2009-06-16 | 2011-08-30 | 전라남도 | Pig Feed Additives for Increased Weight using Herbal Medicine |
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