CN106540157A - A kind of cabrilla composite Chinese herbal immunostimulant - Google Patents

A kind of cabrilla composite Chinese herbal immunostimulant Download PDF

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Publication number
CN106540157A
CN106540157A CN201610914263.2A CN201610914263A CN106540157A CN 106540157 A CN106540157 A CN 106540157A CN 201610914263 A CN201610914263 A CN 201610914263A CN 106540157 A CN106540157 A CN 106540157A
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powder
cabrilla
radix
immunostimulant
herba
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谢钦铭
徐远彬
何文辉
孔江红
周义明
饶泽坤
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Jimei University
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Jimei University
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/287—Chrysanthemum, e.g. daisy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/255—Esters, e.g. nitroglycerine, selenocyanates of sulfoxy acids or sulfur analogues thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/722—Chitin, chitosan
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/02—Algae
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/238—Saposhnikovia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284—Atractylodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/35—Caprifoliaceae (Honeysuckle family)
    • A61K36/355—Lonicera (honeysuckle)
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481—Astragalus (milkvetch)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/535—Perilla (beefsteak plant)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
    • A61K36/605—Morus (mulberry)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/78—Saururaceae (Lizard's-tail family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/898—Orchidaceae (Orchid family)
    • A61K36/8984—Dendrobium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/90—Smilacaceae (Catbrier family), e.g. greenbrier or sarsaparilla
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/904—Stemonaceae (Stemona family), e.g. croomia
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/80—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in fisheries management
    • Y02A40/81—Aquaculture, e.g. of fish
    • Y02A40/818—Alternative feeds for fish, e.g. in aquacultures

Abstract

The invention discloses a kind of cabrilla composite Chinese herbal immunostimulant, in percentage by weight, is made up of following raw material：Flos Chrysanthemi powder 8～10%, mountain Soviet Union powder 8～10%, Sargassum powder 8～10%, powder of Folium Mori 8～10%, Radix Dauci Sativae powder 8～10%, moringa powder 8～10%, Herba Agrimoniae 5～7%, Folium Perillae 5～7%, the Radix Astragali 5～7%, Rhizoma Smilacis Glabrae 3～5%, Herba Houttuyniae 3～5%, the Radix Stemonae 3～5%, Flos Lonicerae 3～5%, the Rhizoma Atractylodis Macrocephalae 3～5%, Radix Saposhnikoviae 3～5%, garlicin 1～3%, low shitosan 0.5～1.5%, Herba Dendrobii 0.5～1.5%.Instant component collocation is reasonable, while drug effect is strengthened, does not have toxicity to cabrilla, has two attribute of nutrition and medicine concurrently, quite notable to improving cabrilla immunity effect；It is added in normal feedstuff with the amount of normal feedstuff weight 0.8～3%, addition is few, with low cost, easy to use.

Description

A kind of cabrilla composite Chinese herbal immunostimulant
Technical field
The present invention relates to field of feed additive technology, specifically a kind of cabrilla composite Chinese herbal immunostimulant.
Background technology
Cabrilla, as the most famous and precious economic fish of sea-farming, especially in Southeast Asia, Japan and Hongkong and Macro market, is a kind of High-grade marine product.In recent years, with cabrilla artificial cultivation industry development, the disease incidence of cabrilla also substantially on Rise, often because the originals such as disease thus result in massive mortality, the economic loss of heaviness is caused to vast cultivation dealer.These problems Outlet and the fanning economics of China's cabrilla are had a strong impact on.
With the expansion of intensive culture Grouper cultivating scale, the immunity degradation of cabrilla is caused and has caused a disease harmful drawing Play dead phenomenon.In order to reduce the sickness rate of cabrilla, improve cultivation survival rate, the economy damage that disease takes place frequently brought is prevented Lose, people can only widely use various sterilizing medicines in breeding process and antibiosis is usually prevented and treated, and these medicines Thing（Including antibiotic）A large amount of uses certainly will cause the appearance of Resistant strain, inevitably remain in fish body, to fish The injury of class internal organs is serious, and produced drug residue and diffusion problem in the environment have had a strong impact on food peace Complete and environment public health security.Therefore, the immunity of cabrilla body how is improved, the invasion of disease is effective against, is reduced Morbidity and mortality rate, become the point of penetration that people prevent and treat cabrilla pest and disease damage.Chinese herbal medicine is used as a kind of green non-pollution Resource has been widely applied in the research and development of Medicines in Aquaculture, is had broad application prospects, but so far, be yet there are no specially Door is applied to the relevant report of the Chinese medicine formula for improving cabrilla immunity.
The content of the invention
It is an object of the invention to provide a kind of cabrilla of pure natural, drug residue free composite Chinese herbal immunostimulant Agent.
For achieving the above object, the present invention provides following technical scheme：
A kind of cabrilla composite Chinese herbal immunostimulant, in percentage by weight, is made up of following raw material：Flos Chrysanthemi powder 8 ～10%, mountain Soviet Union powder 8～10%, Sargassum powder 8～10%, powder of Folium Mori 8～10%, Radix Dauci Sativae powder 8～10%, moringa powder 8～10%, red crowned crane Grass 5～7%, Folium Perillae 5～7%, the Radix Astragali 5～7%, Rhizoma Smilacis Glabrae 3～5%, Herba Houttuyniae 3～5%, the Radix Stemonae 3～5%, Flos Lonicerae 3～5%, in vain Art 3～5%, Radix Saposhnikoviae 3～5%, garlicin 1～3%, low shitosan 0.5～1.5%, Herba Dendrobii 0.5～1.5%.
As further scheme of the invention：In percentage by weight, it is made up of following raw material：Flos Chrysanthemi powder 9%, mountain Soviet Union Powder 9%, Sargassum powder 9%, powder of Folium Mori 9%, Radix Dauci Sativae powder 9%, moringa powder 9%, Herba Agrimoniae 6%, Folium Perillae 6%, the Radix Astragali 6%, Rhizoma Smilacis Glabrae 4%, fish Raw meat grass 4%, the Radix Stemonae 4%, Flos Lonicerae 4%, the Rhizoma Atractylodis Macrocephalae 4%, Radix Saposhnikoviae 4%, garlicin 2%, low shitosan 1%, Herba Dendrobii 1%.
As further scheme of the invention：Described Flos Chrysanthemi powder, mountain Soviet Union powder, Sargassum powder, powder of Folium Mori, Radix Dauci Sativae powder, Moringa Powder, Herba Agrimoniae, Folium Perillae, the Radix Astragali, Rhizoma Smilacis Glabrae, Herba Houttuyniae, the Radix Stemonae, Flos Lonicerae, the Rhizoma Atractylodis Macrocephalae, Radix Saposhnikoviae, garlicin, low shitosan, iron sheet Herba Dendrobii is 150～200 mesh siftage.
As further scheme of the invention：By using cooperatively with epinephelus feed, with epinephelus feed during use Proportioning is：Add 8～30g cabrillas composite Chinese herbal immunostimulant, i.e., 0.8～3% addition in 1kg epinephelus feeds Amount.
The described cabrilla preparation method of composite Chinese herbal immunostimulant, concretely comprises the following steps：By Flos Chrysanthemi powder, mountain Soviet Union Powder, Sargassum powder, powder of Folium Mori, Radix Dauci Sativae powder, moringa powder, Herba Agrimoniae, Folium Perillae, the Radix Astragali, Rhizoma Smilacis Glabrae, Herba Houttuyniae, the Radix Stemonae, Flos Lonicerae, in vain Art, Radix Saposhnikoviae, garlicin, low shitosan, Herba Dendrobii cross 150～200 mesh sieves after carrying out Crushing of Ultrafine, stir according to proportioning Afterwards, pelletize is carried out using bed spray technology：Particle diameter is 0.1～0.5mm, and subpackage, sealing after cooling obtains final product cabrilla with again Close Chinese medicine immunity enhancer.Feed by stirring with epinephelus feed during use.
Compared with prior art, the invention has the beneficial effects as follows：
（1）Component scientific compatibility, collocation are reasonable, formulation principle of the raw material according to Chinese herbal medicine, while drug effect is strengthened, to lithosporic Fish does not have toxicity, i.e., do not result in injury to the internal organs of cabrilla, has two attribute of nutrition and medicine concurrently, exempts to improving cabrilla Epidemic disease power effect is quite notable；
（2）Without medicine, degradable, has no toxic side effect pure natural under field conditions (factors), does not interfere with the orthobiosiss of cabrilla, Noresidue in cabrilla body；
（3）It is added in normal feedstuff with the amount of normal feedstuff weight 0.8～3%, addition is few, easy to use；
（4）Raw materials used wide material sources and stablize, cheap, simple production process.
Specific embodiment
Below in conjunction with the embodiment of the present invention, the technical scheme in the embodiment of the present invention is clearly and completely described, Obviously, described embodiment is only a part of embodiment of the invention, rather than the embodiment of whole.Based in the present invention Embodiment, the every other embodiment obtained under the premise of creative work is not made by those of ordinary skill in the art, all Belong to the scope of protection of the invention.
Embodiment 1
In the embodiment of the present invention, a kind of cabrilla composite Chinese herbal immunostimulant, in percentage by weight, by following original Material composition：Flos Chrysanthemi powder 8%, mountain Soviet Union powder 10%, Sargassum powder 8%, powder of Folium Mori 10%, Radix Dauci Sativae powder 8%, moringa powder 10%, Herba Agrimoniae 7% are purple Soviet Union 5%, the Radix Astragali 7%, Rhizoma Smilacis Glabrae 3%, Herba Houttuyniae 5%, the Radix Stemonae 3%, Flos Lonicerae 5%, the Rhizoma Atractylodis Macrocephalae 3%, Radix Saposhnikoviae 5%, garlicin 1%, low shitosan 1.5%, Herba Dendrobii 0.5%；Its preparation process is：By Flos Chrysanthemi powder, mountain Soviet Union powder, Sargassum powder, powder of Folium Mori, Radix Dauci Sativae powder, moringa powder, Herba Agrimoniae, Folium Perillae, the Radix Astragali, Rhizoma Smilacis Glabrae, Herba Houttuyniae, the Radix Stemonae, Flos Lonicerae, the Rhizoma Atractylodis Macrocephalae, Radix Saposhnikoviae, garlicin, low shitosan, Herba Dendrobii Filtered with 150～200 mesh Microfilters after crushing respectively, mixed according to proportioning extracting screen underflow, after stirring, sprayed using fluid bed Mist technology carries out pelletize：Particle diameter is 0.1～0.5mm, and subpackage, sealing after cooling obtains final product cabrilla composite Chinese herbal immunostimulant Agent.The cabrilla composite Chinese herbal immunostimulant is added in the commercial diet of cabrilla, is added in 1kg epinephelus feeds Plus 10g, the granule that particle diameter is 3mm is made after mixing with minitype fodder-pelleting machine.
Embodiment 2
In the embodiment of the present invention, a kind of cabrilla composite Chinese herbal immunostimulant, in percentage by weight, by following original Material composition：Flos Chrysanthemi powder 9%, mountain Soviet Union powder 9%, Sargassum powder 9%, powder of Folium Mori 9%, Radix Dauci Sativae powder 9%, moringa powder 9%, Herba Agrimoniae 6%, Folium Perillae 6%, the Radix Astragali 6%, Rhizoma Smilacis Glabrae 4%, Herba Houttuyniae 4%, the Radix Stemonae 4%, Flos Lonicerae 4%, the Rhizoma Atractylodis Macrocephalae 4%, Radix Saposhnikoviae 4%, garlicin 2%, low shitosan 1%, Herba Dendrobii 1%；Its preparation process is：By Flos Chrysanthemi powder, mountain Soviet Union powder, Sargassum powder, powder of Folium Mori, Radix Dauci Sativae powder, moringa powder, red crowned crane Grass, Folium Perillae, the Radix Astragali, Rhizoma Smilacis Glabrae, Herba Houttuyniae, the Radix Stemonae, Flos Lonicerae, the Rhizoma Atractylodis Macrocephalae, Radix Saposhnikoviae, garlicin, low shitosan, Herba Dendrobii difference Filtered with 150～200 mesh Microfilters after crushing, mixed according to proportioning extracting screen underflow, after stirring, using bed spray skill Art carries out pelletize：Particle diameter is 0.1～0.5mm, and subpackage, sealing after cooling obtains final product cabrilla composite Chinese herbal immunostimulant. The cabrilla composite Chinese herbal immunostimulant is added in the commercial diet of cabrilla, is added in 1kg epinephelus feeds 10g, makes the granule that particle diameter is 3mm with minitype fodder-pelleting machine after mixing.
Embodiment 3
In the embodiment of the present invention, a kind of cabrilla composite Chinese herbal immunostimulant, in percentage by weight, by following original Material composition：Flos Chrysanthemi powder 10%, mountain Soviet Union powder 8%, Sargassum powder 10%, powder of Folium Mori 8%, Radix Dauci Sativae powder 10%, moringa powder 8%, Herba Agrimoniae 5% are purple Soviet Union 7%, the Radix Astragali 5%, Rhizoma Smilacis Glabrae 5%, Herba Houttuyniae 3%, the Radix Stemonae 5%, Flos Lonicerae 3%, the Rhizoma Atractylodis Macrocephalae 5%, Radix Saposhnikoviae 3%, garlicin 3%, low shitosan 0.5%, Herba Dendrobii 1.5%；Its preparation process is：By Flos Chrysanthemi powder, mountain Soviet Union powder, Sargassum powder, powder of Folium Mori, Radix Dauci Sativae powder, moringa powder, Herba Agrimoniae, Folium Perillae, the Radix Astragali, Rhizoma Smilacis Glabrae, Herba Houttuyniae, the Radix Stemonae, Flos Lonicerae, the Rhizoma Atractylodis Macrocephalae, Radix Saposhnikoviae, garlicin, low shitosan, Herba Dendrobii Filtered with 150～200 mesh Microfilters after crushing respectively, mixed according to proportioning extracting screen underflow, after stirring, sprayed using fluid bed Mist technology carries out pelletize：Particle diameter is 0.1～0.5mm, and subpackage, sealing after cooling obtains final product cabrilla composite Chinese herbal immunostimulant Agent.The cabrilla composite Chinese herbal immunostimulant is added in the commercial diet of cabrilla, is added in 1kg epinephelus feeds Plus 10g, the granule that particle diameter is 3mm is made after mixing with minitype fodder-pelleting machine.
According to feedstuff feeding cabrilla 45 days made by the composition of raw materials in embodiment 1～3, test in 4 groups of indoor temperature controls Carry out in circulating water chennel, per tank, cultivation cabrilla is each 50, wherein 3 tanks feed respectively Material, another set only throw normal feedstuff for matched group.
Feeding effect and salivary lysozyme measurement result are as shown in table 1 below.
1 Grouper cultivating result of the test of table
As a result show：Cabrilla composite Chinese herbal immunostimulant of the present invention is added in normal diet and feeds cabrilla, The feed coefficient of cabrilla does not reduce 11～15% than control component, and survival rate improves 11～17%.And embodiment 1～3 is supported The cabrilla items nonspecific immunity power average index grown（WBC, AKP, serum lysozyme level and SOD）It is all remarkably higher than control Group.
It is obvious to a person skilled in the art that the invention is not restricted to the details of above-mentioned one exemplary embodiment, Er Qie In the case of spirit or essential attributes without departing substantially from the present invention, the present invention can be realized in other specific forms.Therefore, no matter From the point of view of which point, embodiment all should be regarded as exemplary, and be nonrestrictive, the scope of the present invention is by appended power Profit is required rather than described above is limited, it is intended that all in the implication and scope of the equivalency of claim by falling Change is included in the present invention.
Moreover, it will be appreciated that although this specification is been described by according to embodiment, not each embodiment is only wrapped Containing an independent technical scheme, this narrating mode of description is only that those skilled in the art should for clarity Using description as an entirety, the technical scheme in each embodiment can also Jing it is appropriately combined, form those skilled in the art Understandable other embodiment.

Claims (4)

1. a kind of cabrilla composite Chinese herbal immunostimulant, it is characterised in that in percentage by weight, by following raw material Composition：Flos Chrysanthemi powder 8～10%, mountain Soviet Union powder 8～10%, Sargassum powder 8～10%, powder of Folium Mori 8～10%, Radix Dauci Sativae powder 8～10%, moringa powder 8～10%, Herba Agrimoniae 5～7%, Folium Perillae 5～7%, the Radix Astragali 5～7%, Rhizoma Smilacis Glabrae 3～5%, Herba Houttuyniae 3～5%, the Radix Stemonae 3～5%, gold silver Spend 3～5%, the Rhizoma Atractylodis Macrocephalae 3～5%, Radix Saposhnikoviae 3～5%, garlicin 1～3%, low shitosan 0.5～1.5%, Herba Dendrobii 0.5～1.5%.
2. cabrilla according to claim 1 composite Chinese herbal immunostimulant, it is characterised in that according to weight percent Than meter, it is made up of following raw material：Flos Chrysanthemi powder 9%, mountain Soviet Union powder 9%, Sargassum powder 9%, powder of Folium Mori 9%, Radix Dauci Sativae powder 9%, moringa powder 9% are celestial Crane grass 6%, Folium Perillae 6%, the Radix Astragali 6%, Rhizoma Smilacis Glabrae 4%, Herba Houttuyniae 4%, the Radix Stemonae 4%, Flos Lonicerae 4%, the Rhizoma Atractylodis Macrocephalae 4%, Radix Saposhnikoviae 4%, garlicin 2%, low shitosan 1%, Herba Dendrobii 1%.
3. according to the arbitrary described cabrilla composite Chinese herbal immunostimulant of claim 1～2, it is characterised in that described Flos Chrysanthemi powder, mountain Soviet Union powder, Sargassum powder, powder of Folium Mori, Radix Dauci Sativae powder, moringa powder, Herba Agrimoniae, Folium Perillae, the Radix Astragali, Rhizoma Smilacis Glabrae, Herba Houttuyniae, The Radix Stemonae, Flos Lonicerae, the Rhizoma Atractylodis Macrocephalae, Radix Saposhnikoviae, garlicin, low shitosan, Herba Dendrobii are 150～200 mesh siftage.
4. cabrilla according to claim 3 composite Chinese herbal immunostimulant, it is characterised in that by with cabrilla Feed formulation is used, and during use with the proportioning of epinephelus feed is：Add 8～30g cabrillas in 1kg epinephelus feeds and use compound Chinese medicine immunity enhancer.
CN201610914263.2A 2016-10-20 2016-10-20 A kind of cabrilla composite Chinese herbal immunostimulant Pending CN106540157A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107211958A (en) * 2017-07-07 2017-09-29 宣汉县蜀宣花牛养殖专业合作社 A kind of another name for Sichuan Province a surname flower ox cow concentrates method for breeding
CN107691901A (en) * 2017-11-29 2018-02-16 衡阳县福茂农林生态有限公司 Feed addictive, preparation method and application for crucian
CN108783007A (en) * 2018-07-20 2018-11-13 广东天地本草饲料科技股份有限公司 A kind of fishes and shrimps feed addictive and its preparation method and application

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Publication number Priority date Publication date Assignee Title
CN102934740A (en) * 2012-11-23 2013-02-20 浙江海洋学院 Composite immunopotentiator for garrupa

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102934740A (en) * 2012-11-23 2013-02-20 浙江海洋学院 Composite immunopotentiator for garrupa

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107211958A (en) * 2017-07-07 2017-09-29 宣汉县蜀宣花牛养殖专业合作社 A kind of another name for Sichuan Province a surname flower ox cow concentrates method for breeding
CN107691901A (en) * 2017-11-29 2018-02-16 衡阳县福茂农林生态有限公司 Feed addictive, preparation method and application for crucian
CN108783007A (en) * 2018-07-20 2018-11-13 广东天地本草饲料科技股份有限公司 A kind of fishes and shrimps feed addictive and its preparation method and application

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Application publication date: 20170329