CN104257784A - Chinese herbal medicine formula for preventing and treating European foul brood of Apis cerana - Google Patents
Chinese herbal medicine formula for preventing and treating European foul brood of Apis cerana Download PDFInfo
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- CN104257784A CN104257784A CN201410499599.8A CN201410499599A CN104257784A CN 104257784 A CN104257784 A CN 104257784A CN 201410499599 A CN201410499599 A CN 201410499599A CN 104257784 A CN104257784 A CN 104257784A
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- foul brood
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- european foul
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/718—Coptis (goldthread)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/288—Taraxacum (dandelion)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/35—Caprifoliaceae (Honeysuckle family)
- A61K36/355—Lonicera (honeysuckle)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/536—Prunella or Brunella (selfheal)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
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- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
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Abstract
The invention discloses a Chinese herbal medicine formula for preventing and treating European foul brood of Apis cerana. The Chinese herbal medicine formula consists of the following components in percentage by mass: 22-27 percent of coptis chinensis, 21-25 percent of selfheal, 18-26 percent of astragalus polysaccharide, 18-22 percent of dandelion and 12-16 percent of honeysuckle, totaling 100 percent. The Chinese herbal medicine formula for preventing and treating European foul brood of Apis cerana disclosed by the invention has the effects of enhancing the stress resistance, obviously reducing the incidence rate and disease index and promoting the swarm development and reproduction. Meanwhile, the preparation is simple to prepare, easy to preserve, simple and feasible, and industrialized production can be realized.
Description
Technical field:
The invention belongs to Apis field of pest control, be specifically related to honeybee European foul brood control herbal prescription in one.
Background technology:
The pernicious infectious disease of bee larvae that European foul brood causes primarily of Bee venoms, honeybee in main harm; First this disease infects the Apis small grub of 1-2 age in days, after 2-3 days incubation periods, how dead when the non-capping of 3-4 age in days, has the feature of propagation and rapid onset.
In order to control European foul brood, tetracycline antibiotics is usually used in preventing and treating this disease.Because abuse abused by medicine, create resistance problems; And people start care and recognize food-safety problem, drug residue receives much concern; The countries such as Europe detect extremely strict to the drug residue of bee product; Have a strong impact on foreign exchange earning.Therefore, in the herbal control of natural green, honeybee European foul brood is imperative.
Summary of the invention:
The object of this invention is to provide the middle honeybee European foul brood control herbal prescription that a kind of centering honeybee European foul brood has obvious prevention effect.
Middle honeybee European foul brood control herbal prescription of the present invention, it is characterized in that, by mass fraction 100%, be made up of following component, Rhizoma Coptidis 22% ~ 27%, Spica Prunellae 21% ~ 25%, astragalus polysaccharides 18% ~ 26%, Herba Taraxaci 18% ~ 22% and Flos Lonicerae 12% ~ 16%.
Preferably, described middle honeybee European foul brood control herbal prescription, by mass fraction 100%, is made up of following component, Rhizoma Coptidis 25%, Spica Prunellae 20%, astragalus polysaccharides 20%, Herba Taraxaci 20% and Flos Lonicerae 15%.
The preparation method of middle honeybee European foul brood control herbal prescription of the present invention is: Chinese herbal medicine sterling is milled to Powdered, according to its ratio mix homogeneously.It is instant powder agent.Drug packages: 5.0g/ wraps.
The using method of middle honeybee European foul brood control herbal prescription of the present invention: add honeybee European foul brood control herbal prescription (5.0g/ bag) in a bag in first a small amount of warm water, then appropriate syrup (sugar: water=1:1 is added, common syrup) in, obtained medicated syrup; Secondly, time at dusk, medicated syrup is added in feeder, its Apis is freely taken food.Often bag medicine can be used for the bee colony use of 3 ~ 4 frame group gesture, specifically takes the circumstances into consideration increase and decrease according to group's gesture.Once a day, feed continuously 3 days; 3 days, interval, continues to feed; Circulation is fed 4 times continuously.
Prove by experiment, in employing, the bee colony of Tinea Apis Europe decaying disease in the control of honeybee European foul brood control herbal prescription, not only improves bee colony immunity, and effectively preventing European foul brood outburst and popular.
Middle honeybee European foul brood control herbal prescription of the present invention has enhancing resistance, obviously reduces sickness rate and disease index, promotes bee colony group gesture development breeding; Said preparation makes simply, is easy to preserve, be simple and easy to use simultaneously, can carry out industrialization production.
Accompanying drawing illustrates:
Fig. 1 is drug use sequela rate situation of change figure, and wherein common syrup refers to and do not add middle honeybee European foul brood control herbal prescription, and during medicated syrup refers to and adds in common syrup, honeybee European foul brood control herbal prescription, lower same;
Fig. 2 is the disease index figure after bee colony medication;
Fig. 3 is feed common syrup and medicated syrup bee colony group gesture figure.
Detailed description of the invention:
Following examples further illustrate of the present invention, instead of limitation of the present invention.
Embodiment 1:
The middle honeybee European foul brood control herbal prescription of the present embodiment, by mass fraction 100%, is made up of following component, Rhizoma Coptidis 25%, Spica Prunellae 20%, astragalus polysaccharides 20%, Herba Taraxaci 20% and Flos Lonicerae 15%.
According to the mass ratio of above-mentioned each raw material, weigh each raw material respectively, more respectively each raw material grinding mill is broken into Powdered, then mix homogeneously, namely obtain the middle honeybee European foul brood control herbal prescription of the present embodiment.It is instant powder agent.Drug packages: 5.0g/ wraps.
Curative effect of medication is tested:
In plant disease epidemic season, clinical trial is carried out in Guangzhou Guangdong, first add middle honeybee European foul brood control herbal prescription (5.0g/ bag) of a bag the present embodiment in a small amount of warm water, then add appropriate syrup (sugar: water=1:1); Secondly, time at dusk, medicated syrup is added in feeder, its Apis is freely taken food.Often bag medicine can be used for the bee colony use of 3 ~ 4 frame group gesture, specifically takes the circumstances into consideration increase and decrease according to group's gesture.Once a day, feed continuously 3 days; 3 days, interval, continues to feed; Circulation is fed 4 times continuously.Medication is after 42 days, and (sickness rate was observed once from medication same day for every 6 days; The change of group's gesture is observed once for every 11 days from medication same day) disease index of medication treatment bee colony (30 groups), sickness rate and the change of bee colony group gesture, pole significant difference is had, the therapeutic effect that medicine tool is good compared with contrasting bee colony (common syrup of only feeding) with non-medication.The sickness rate of medication bee colony is by 70%, drop to 10% (Fig. 1), sick control effective percentage can reach more than 86%, from medication same day, (within every 11 days, observed once) disease index after diseased bee colonies (30 groups) medication four times drop to 0.05 (Fig. 2) by 0.38, the bee colony group gesture significant change of medication is better than the bee colony (Fig. 3) of non-medication.
As can be seen here, the middle honeybee European foul brood protective agents of the present embodiment has enhancing resistance, obviously reduces sickness rate and disease index, promotes bee colony group gesture development breeding.
Embodiment 2:
The middle honeybee European foul brood control herbal prescription of the present embodiment, by mass fraction 100%, is made up of following component, Rhizoma Coptidis 22%, Spica Prunellae 25%, astragalus polysaccharides 18%, Herba Taraxaci 22% and Flos Lonicerae 13%.
According to the mass ratio of above-mentioned each raw material, weigh each raw material respectively, more respectively each raw material grinding mill is broken into Powdered, then mix homogeneously, namely obtain the middle honeybee European foul brood control herbal prescription of the present embodiment.It is instant powder agent.Drug packages: 5.0g/ wraps.
Carry out the test of pesticide effectiveness according to the method for embodiment 1, result shows, the middle honeybee European foul brood protective agents of the present embodiment has enhancing resistance, obviously reduces sickness rate and disease index, promotes bee colony group gesture development breeding.
Embodiment 3:
The middle honeybee European foul brood control herbal prescription of the present embodiment, by mass fraction 100%, is made up of following component, Rhizoma Coptidis 27%, Spica Prunellae 21%, astragalus polysaccharides 22%, Herba Taraxaci 18% and Flos Lonicerae 12%.
According to the mass ratio of above-mentioned each raw material, weigh each raw material respectively, more respectively each raw material grinding mill is broken into Powdered, then mix homogeneously, namely obtain the middle honeybee European foul brood control herbal prescription of embodiment.It is instant powder agent.Drug packages: 5.0g/ wraps.
Carry out the test of pesticide effectiveness according to the method for embodiment 1, result shows, the middle honeybee European foul brood protective agents of the present embodiment has enhancing resistance, obviously reduces sickness rate and disease index, promotes bee colony group gesture development breeding.
Embodiment 4:
The middle honeybee European foul brood control herbal prescription of the present embodiment, by mass fraction 100%, is made up of following component, Rhizoma Coptidis 22%, Spica Prunellae 21%, astragalus polysaccharides 26%, Herba Taraxaci 15% and Flos Lonicerae 16%.
According to the mass ratio of above-mentioned each raw material, weigh each raw material respectively, more respectively each raw material grinding mill is broken into Powdered, then mix homogeneously, namely obtain the middle honeybee European foul brood control herbal prescription of embodiment.It is instant powder agent.Drug packages: 5.0g/ wraps.
Carry out the test of pesticide effectiveness according to the method for embodiment 1, result shows, the middle honeybee European foul brood protective agents of the present embodiment has enhancing resistance, obviously reduces sickness rate and disease index, promotes bee colony group gesture development breeding.
Claims (2)
1. honeybee European foul brood control herbal prescription in a kind, it is characterized in that, by mass fraction 100%, be made up of following component, Rhizoma Coptidis 22% ~ 27%, Spica Prunellae 21% ~ 25%, astragalus polysaccharides 18% ~ 26%, Herba Taraxaci 18% ~ 22% and Flos Lonicerae 12% ~ 16%.
2. middle honeybee European foul brood control herbal prescription according to claim 1, is characterized in that, by mass fraction 100%, be made up of following component, Rhizoma Coptidis 25%, Spica Prunellae 20%, astragalus polysaccharides 20%, Herba Taraxaci 20% and Flos Lonicerae 15%.
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| CN201410499599.8A CN104257784B (en) | 2014-09-25 | 2014-09-25 | A kind of middle honeybee European foul brood preventing and treating herbal prescription |
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| CN201410499599.8A CN104257784B (en) | 2014-09-25 | 2014-09-25 | A kind of middle honeybee European foul brood preventing and treating herbal prescription |
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| CN104257784B CN104257784B (en) | 2017-10-27 |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107375552A (en) * | 2017-07-26 | 2017-11-24 | 贵州务川麻阳河蜂业开发有限公司 | A kind of preventing and treating composition of bee European foul brood and preparation method thereof |
| CN109045134A (en) * | 2018-09-20 | 2018-12-21 | 中国农业科学院蜜蜂研究所 | Application of the madder in prevention and treatment Bee venoms |
| CN110124003A (en) * | 2019-06-26 | 2019-08-16 | 袁风格 | A kind of Chinese herbal medicine and preparation method thereof for preventing and treating the rotten young disease of Chinese bee |
Citations (3)
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| CN102356821A (en) * | 2011-09-21 | 2012-02-22 | 广东省昆虫研究所 | Apis cerana cerana health care feed |
| CN102379950A (en) * | 2010-08-27 | 2012-03-21 | 蒋春辉 | Preparation method of bee larva recuperated medicine |
| CN103301208A (en) * | 2013-05-28 | 2013-09-18 | 福建农林大学 | Chinese herbal medicinal preparation for preventing and treating Chinese sacbrood |
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2014
- 2014-09-25 CN CN201410499599.8A patent/CN104257784B/en active Active
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| CN102356821A (en) * | 2011-09-21 | 2012-02-22 | 广东省昆虫研究所 | Apis cerana cerana health care feed |
| CN103301208A (en) * | 2013-05-28 | 2013-09-18 | 福建农林大学 | Chinese herbal medicinal preparation for preventing and treating Chinese sacbrood |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107375552A (en) * | 2017-07-26 | 2017-11-24 | 贵州务川麻阳河蜂业开发有限公司 | A kind of preventing and treating composition of bee European foul brood and preparation method thereof |
| CN109045134A (en) * | 2018-09-20 | 2018-12-21 | 中国农业科学院蜜蜂研究所 | Application of the madder in prevention and treatment Bee venoms |
| CN109045134B (en) * | 2018-09-20 | 2021-05-28 | 中国农业科学院蜜蜂研究所 | Application of madder in preventing and treating bee-brood cocci |
| CN110124003A (en) * | 2019-06-26 | 2019-08-16 | 袁风格 | A kind of Chinese herbal medicine and preparation method thereof for preventing and treating the rotten young disease of Chinese bee |
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| Publication number | Publication date |
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| CN104257784B (en) | 2017-10-27 |
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Address after: 510260 Xingang West Road, Guangdong, Guangzhou, No. 105, No. Applicant after: Guangdong Institute of biological resources application Address before: 510260 Xingang West Road, Guangdong, Guangzhou, No. 105, No. Applicant before: Guangdong Entomological Institute |
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Address after: 510260 No. 105 West Xingang Road, Guangzhou, Guangdong, Haizhuqu District Patentee after: Institute of zoology, Guangdong Academy of Sciences Address before: 510260 No. 105 West Xingang Road, Guangzhou, Guangdong, Haizhuqu District Patentee before: Guangdong Institute of Applied Biological Resources |
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