CN102885901A - Traditional Chinese medicine composition for preventing and treating black gill disease of fishes - Google Patents
Traditional Chinese medicine composition for preventing and treating black gill disease of fishes Download PDFInfo
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- CN102885901A CN102885901A CN2011102034422A CN201110203442A CN102885901A CN 102885901 A CN102885901 A CN 102885901A CN 2011102034422 A CN2011102034422 A CN 2011102034422A CN 201110203442 A CN201110203442 A CN 201110203442A CN 102885901 A CN102885901 A CN 102885901A
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Abstract
The invention relates to a traditional Chinese medicine composition for preventing and treating a black gill disease of fishes, wherein the traditional Chinese medicine composition comprises the following components by weight: 5 to 30 parts of rheum officinale, 10 to 30 parts of radix scutellariae, 10 to 30 parts of radix isatidis, 10 to 30 parts of flos lonicerae, 5 to 25 parts of polygonum cuspidatum, and 5 to 25 parts of herba ecliptae. A formula provided by the invention is scientific and reasonable in constitution, takes effect quickly, and has the effects of good broad spectrum antibiosis and antivirus, and is capable of improving immunity, free from toxic and side effects and medicinal residues, low in production cost and convenient to use.
Description
Technical field
The invention belongs to field of veterinary, especially a kind of Chinese medicine composition of preventing and treating the fish rotten cheek and preparation method thereof.
Background technology
China is fishery big country, the aquatic products total amount accounts for 1/3 of world's total amount, the aquaculture amount occupies first place in the world, account for global 2/3, national aquatic products total amount reached 4,570 ten thousand tons in 2002, the cultivation amount reaches more than 2,600 ten thousand tons, and breeding way trends towards intensive, modernization, but when following economic liftoff, various disadvantages also come one after another, such as how precious fish event in 2006, and exceed standard etc. the appearance of problem of the malachite green vestigial in the Siniperca chuatsi body, allow people more pay attention to the safety of food, the health of self, moreover, the series of side effects that antibiotic etc causes is also having a strong impact on the outlet of China's aquatic products, part Anguillar japonica such as Chinese exports Japan of 1998 and 1999 is returned goods because drug residue exceeds standard, and Chinese exports was returned goods because detecting chloromycetin to the Procambarus clarkii of European Union in 2002.Aquatic products are refused example and had both been brought economic loss to country, have also damaged the international image of China Water product simultaneously.Popularization along with the green non-pollution cultural technique, make culture fishery health, sustainable development, the exploitation toxic and side effects is little, noresidue, the Chinese herbal medicine that pathogen is difficult for developing immunity to drugs becomes the emphasis of current Aquatic product drug research, uses Chinese herbal medicine to have advantages of that many chemical substances can not match in excellence or beauty in cultivation and feedstuff.Chinese herbal medicine extracting is in nature and preserved its natural structure and bioactive natural materials, had multiple nutritional components and bioactive substance, low-residual, toxic and side effects be little, multi-functional, can reconcile the physiological function of body comprehensively, has the dual function of nutrient substance and medicine concurrently.Can improve water body environment, improve drug effect, control pathogenic microorganism, thereby the generation of minimizing disease, in recent years, Chinese herbal and crude drugs preparations has obtained increasingly extensive application, is expected to become an in the future new direction of the aquaculture prevention and control of plant diseases, pest control.
Summary of the invention
The object of the invention is to overcome the deficiencies in the prior art, a kind of Chinese medicine composition of preventing and treating the fish rotten cheek is provided, this Chinese medicine composition composition formula forms scientific and reasonable, instant effect, have preferably broad-spectrum antiseptic, antivirus action, and can Effective Raise immunity, have no side effect and drug residue, production cost is lower, and is easy to use.
Another object of the present invention is to provide a kind of preparation method of preventing and treating the Chinese medicine composition of fish rotten cheek.
The present invention is achieved by the following technical solutions:
A kind of Chinese medicine composition of preventing and treating the fish rotten cheek, the component of its Chinese medicine composition and ratio of weight and number thereof are:
Radix Et Rhizoma Rhei 5-30 part;
Radix Scutellariae 10-30 part;
Radix Isatidis 10-30 part;
Flos Lonicerae 10-30 part;
Rhizoma Polygoni Cuspidati 5-25 part;
Herba Ecliptae 5-25 part.
A kind of preparation method of preventing and treating the Chinese medicine composition of fish rotten cheek, the step of its preparation method is:
(1), take by weighing respectively Radix Et Rhizoma Rhei, Radix Scutellariae, Radix Isatidis, Flos Lonicerae, Rhizoma Polygoni Cuspidati, Herba Ecliptae according to weight proportion and pulverize, and with every kind of raw material respectively all by 80～100 mesh sieves;
(2), will cross Radix Et Rhizoma Rhei, Radix Scutellariae, Radix Isatidis, Flos Lonicerae, Rhizoma Polygoni Cuspidati, Herba Ecliptae mix homogeneously behind 80～100 mesh sieves, namely obtain the Chinese medicine composition of finished product control fish rotten cheek.
Advantage of the present invention and beneficial effect are:
1. the Radix Et Rhizoma Rhei of the Chinese medicine composition of this control fish rotten cheek, Radix Scutellariae, Radix Isatidis, Flos Lonicerae, Rhizoma Polygoni Cuspidati, Herba Ecliptae have the effect of heat-clearing and toxic substances removing, cooling blood for hemostasis, removing mass clots absorbing.
2. the preparation method of the Chinese medicine composition of this control fish rotten cheek is simple, and cost is lower, and its effective ingredient can easily be absorbed by the fish body, short, instant effect of time.
3. the present invention fills a prescription and forms scientific and reasonablely, and instant effect has preferably broad-spectrum antiseptic, antivirus action, and can Effective Raise immunity, has no side effect and drug residue, and production cost is lower, and is easy to use.
The specific embodiment
The present invention is described in further detail by following examples.Need to prove: following embodiment is illustrative, is not determinate, can not limit protection scope of the present invention with following embodiment.
Radix Et Rhizoma Rhei in the component of the present invention, Radix Scutellariae, Radix Isatidis, Flos Lonicerae, Rhizoma Polygoni Cuspidati, Herba Ecliptae all can be bought in market and obtain.
Embodiment 1
A kind of Chinese medicine composition of preventing and treating the fish rotten cheek, component and the weight thereof of its Chinese medicine composition are respectively: Radix Et Rhizoma Rhei 12g, Radix Scutellariae 27g, Radix Isatidis 27g, Flos Lonicerae 27g, Rhizoma Polygoni Cuspidati 5g, Herba Ecliptae 5g.
A kind of preparation method of preventing and treating the Chinese medicine composition of fish rotten cheek, the step of its preparation method is:
(1), take by weighing respectively Radix Et Rhizoma Rhei, Radix Scutellariae, Radix Isatidis, Flos Lonicerae, Rhizoma Polygoni Cuspidati, Herba Ecliptae according to weight proportion and pulverize, and with every kind of raw material respectively all by 80 mesh sieves;
(2), will cross Radix Et Rhizoma Rhei, Radix Scutellariae, Radix Isatidis, Flos Lonicerae, Rhizoma Polygoni Cuspidati, Herba Ecliptae mix homogeneously behind 80 mesh sieves, namely obtain the Chinese medicine composition of finished product control fish rotten cheek.
Embodiment 2
A kind of Chinese medicine composition of preventing and treating the fish rotten cheek, component and the weight thereof of its Chinese medicine composition are respectively: Radix Et Rhizoma Rhei 26g, Radix Scutellariae 30g, Radix Isatidis 30g, Flos Lonicerae 30g, Rhizoma Polygoni Cuspidati 16g, Herba Ecliptae 16g.
The step of its preparation method is with embodiment 1.
Embodiment 3
A kind of Chinese medicine composition of preventing and treating the fish rotten cheek, component and the weight thereof of its Chinese medicine composition are respectively: Radix Et Rhizoma Rhei 17g, Radix Scutellariae 21g, Radix Isatidis 21g, Flos Lonicerae 21g, Rhizoma Polygoni Cuspidati 8g, Herba Ecliptae 8g.
The step of its preparation method is with embodiment 1.
Embodiment 4
A kind of Chinese medicine composition of preventing and treating the fish rotten cheek, component and the weight thereof of its Chinese medicine composition are respectively: Radix Et Rhizoma Rhei 5g, Radix Scutellariae 10g, Radix Isatidis 10g, Flos Lonicerae 10g, Rhizoma Polygoni Cuspidati 15g, Herba Ecliptae 15g.
The step of its preparation method is with embodiment 1.
Embodiment 5
A kind of Chinese medicine composition of preventing and treating the fish rotten cheek, component and the weight thereof of its Chinese medicine composition are respectively: Radix Et Rhizoma Rhei 10g, Radix Scutellariae 15g, Radix Isatidis 15g, Flos Lonicerae 15g, Rhizoma Polygoni Cuspidati 20g, Herba Ecliptae 20g.
The step of its preparation method is with embodiment 1.
The present invention in use can stir the present invention in feedstuff, and is edible for fish after fully mixing, and adds Chinese medicine composition 5kg～30kg of the present invention in every 100Kg fish meal.
Clinical trial
Test 1
Select 6 net cages, each net cage 200 tail Ctenopharyngodon idellus), be divided at random two groups, every group of 3 repetitions, one group is carried out daily raising, and another group is added the present invention in feedstuff, test period is two months, has carried out clinical pharmacodynamics test of the present invention, result of the test such as following table:
Result of the test shows, administration forms motility rate all apparently higher than daily raising group, and total survival rate reaches 95%.With SPSS11.0 statistics software analysis, of the present invention group and daily raising composition motility rate significant difference (p＜0.05).
Test 2
Outburst is tested for Xiqing District raiser Ctenopharyngodon idellus gill rot, every mouthful of pond 700 tail Ctenopharyngodon idellus, and wherein 3 mouthfuls of ponds take traditional method to treat, and 3 mouthfuls of ponds adopt the present invention to treat result of the test such as following table:
Result of the test shows, the present invention forms motility rate apparently higher than the traditional treatment group, and total survival rate reaches 90.8%. with SPSS11.0 statistics software analysis, and of the present invention group forms motility rate significant difference (P＜0.05) with daily raising.
The characteristic of component of the present invention:
Radix Et Rhizoma Rhei is conventional Chinese medicine, has purging heat and dredging bowels, removing pathogenic heat from blood and toxic substance from the body, the effect of eliminating blood stasis and inducing menstruation.Radix Et Rhizoma Rhei has the effects such as hepatic cholagogic to digestive system; Blood system had anastalsis, simultaneously hypercholesterolemia reducing, triglyceride, low density lipoprotein, LDL, very low density lipoprotein (VLDL) and lipid peroxide; Radix Et Rhizoma Rhei can affect enzyme system, anti-bacteria nucleic acid and protein synthesis, anti-bacteria biological oxidation enzyme system, the inducement interferon of folic acid, so played antibacterial action; Radix Et Rhizoma Rhei also has antiinflammatory, refrigeration function, and can regulate immune system.
Radix Isatidis has antibiosis and antiviral functions: the Isatis indigotica Fort. root has inhibitory action to various bacteria.Infusion is to bacillus subtilis, staphylococcus aureus, and sarcine, escherichia coli, Bacillus typhi, paratyphoid fever bacillus, dysentery (will Hayes, Fu Shi) bacillus, bacillus enteritidis etc. have inhibitory action; The acetone leachate also has similar effect, and to Hemolytic streptococcus effective (all using agar aperture flat band method).Also have Detoxication, also can improve immunity.
Radix Scutellariae can have inhibitory action to multiple gram positive bacteria, gram-negative bacteria, pathogenic dermatophytes, has antibiotic, antivirus action; Can suppress inflammatory mediator and produce, discharge, have antiinflammatory action; Improve body's immunity, analgesic.
The Flos Lonicerae heat-clearing and toxic substances removing, wind-heat dissipating.Be used for the carbuncle furuncle, sore throat, erysipelas, warm blood fulminant dysentery, anemopyretic cold, epidemic febrile disease heating.The Flos Lonicerae extract main component is chlorogenic acid, and chlorogenic acid is considered to the main effective ingredient of numerous medical materials and Chinese patent medicine antibacterial and detoxicating, anti-inflammatory and choleretic, usually is used as qualitative even quantitative index.It is reported, the main biological activity of chlorogenic acid has (1) to the inhibitory action of hyaluronidase and glucose～6～phosphatase; (2) to removing and the lipoid peroxidization resistant of free radical; (3) antimutagenesis; (4) hepatic cholagogic effect; (5) effect such as antibiotic, antiviral and spasmolytic.
Rhizoma Polygoni Cuspidati contains knotweed glycoside, organic acid, glycoside, polysaccharide etc.Has heat-clearing and toxic substances removing, promoting the function of the gallbladder to alleviate jaundice, expelling wind and removing dampness, dissipating blood stasis analgesic therapy, relieving cough and resolving phlegm.Be used for arthralgia, jaundice due to damp-heat, amenorrhea ， WEIJIA, cough with copious phlegm, burn due to hot liquid or fire, injury from falling down, carbuncle sore tumefacting virus.
Herba Ecliptae sweet in the mouth, acid, cold in nature.Return kidney, Liver Channel.Aerial parts for feverfew Eclipta prostrata Eclipta prostrasta L..Contain nicotine (nicotine), three thianthrene methanol (a-terthienylmethanol), three thianthrene formaldehyde (a-formyl-a-terthienyl), Saponin, tannin, amaroid, daidzin, wedelolactone etc.Nourishing the liver and kidney, cooling blood for hemostasis.Has anastalsis; Effect to cardiovascular system; . to central nervous system's effect.
Claims (2)
1. Chinese medicine composition of preventing and treating the fish rotten cheek, it is characterized in that: the component of this Chinese medicine composition and ratio of weight and number thereof are:
Radix Et Rhizoma Rhei 5-30 part;
Radix Scutellariae 10-30 part;
Radix Isatidis 10-30 part;
Flos Lonicerae 10-30 part;
Rhizoma Polygoni Cuspidati 5-25 part;
Herba Ecliptae 5-25 part.
2. the preparation method of the Chinese medicine composition of a control as claimed in claim 1 fish rotten cheek, it is characterized in that: the step of this preparation method is:
(1), take by weighing respectively Radix Et Rhizoma Rhei, Radix Scutellariae, Radix Isatidis, Flos Lonicerae, Rhizoma Polygoni Cuspidati, Herba Ecliptae according to weight proportion and pulverize, and with every kind of raw material respectively all by 80～100 mesh sieves;
(2), will cross Radix Et Rhizoma Rhei, Radix Scutellariae, Radix Isatidis, Flos Lonicerae, Rhizoma Polygoni Cuspidati, Herba Ecliptae mix homogeneously behind 80～100 mesh sieves, namely obtain the Chinese medicine composition of finished product control fish rotten cheek.
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| CN2011102034422A CN102885901A (en) | 2011-07-20 | 2011-07-20 | Traditional Chinese medicine composition for preventing and treating black gill disease of fishes |
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| CN2011102034422A CN102885901A (en) | 2011-07-20 | 2011-07-20 | Traditional Chinese medicine composition for preventing and treating black gill disease of fishes |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103432261A (en) * | 2013-08-08 | 2013-12-11 | 泰州市春达动物药业饲料有限公司 | Medicine composition for treating fish gill rot disease and preparation method thereof |
| CN104257812A (en) * | 2014-09-29 | 2015-01-07 | 浙江海洋学院 | Fish medicine for treating branchiomycosis |
| CN104435292A (en) * | 2014-12-29 | 2015-03-25 | 杨成胜 | Chinese herbal medicine preparation for preventing leech ulcer disease |
| CN105250406A (en) * | 2015-11-11 | 2016-01-20 | 郑州后羿制药有限公司 | Chinese herbal medicine fermentation extract liquid for preventing and treating viral diseases of freshwater fish and preparation method thereof |
| CN105434706A (en) * | 2016-01-18 | 2016-03-30 | 张嗣喜 | Traditional Chinese medicine composition for treating gill rote disease of fish |
| CN106509486A (en) * | 2016-10-24 | 2017-03-22 | 广西智宝科技有限公司 | Crucian carp feed capable of preventing and treating branchia hyperemia disease and preparation method of crucian carp feed |
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| CN101933981A (en) * | 2010-08-30 | 2011-01-05 | 天津瑞贝特科技发展有限公司 | Traditional Chinese medicinal composition for treating syndrome of liver and gall of aquatic animals and preparation method thereof |
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2011
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101933981A (en) * | 2010-08-30 | 2011-01-05 | 天津瑞贝特科技发展有限公司 | Traditional Chinese medicinal composition for treating syndrome of liver and gall of aquatic animals and preparation method thereof |
Non-Patent Citations (1)
| Title |
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| 于秀清，等: "鱼菌清对鲫鱼烂鳃、烂鳍和肠炎病的临床疗效试验", 《天津农学院学报》 * |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103432261A (en) * | 2013-08-08 | 2013-12-11 | 泰州市春达动物药业饲料有限公司 | Medicine composition for treating fish gill rot disease and preparation method thereof |
| CN103432261B (en) * | 2013-08-08 | 2016-05-11 | 泰州市春达动物药业饲料有限公司 | A kind of pharmaceutical composition for the treatment of fish gill-rot diseases and preparation method thereof |
| CN104257812A (en) * | 2014-09-29 | 2015-01-07 | 浙江海洋学院 | Fish medicine for treating branchiomycosis |
| CN104435292A (en) * | 2014-12-29 | 2015-03-25 | 杨成胜 | Chinese herbal medicine preparation for preventing leech ulcer disease |
| CN105250406A (en) * | 2015-11-11 | 2016-01-20 | 郑州后羿制药有限公司 | Chinese herbal medicine fermentation extract liquid for preventing and treating viral diseases of freshwater fish and preparation method thereof |
| CN105434706A (en) * | 2016-01-18 | 2016-03-30 | 张嗣喜 | Traditional Chinese medicine composition for treating gill rote disease of fish |
| CN106509486A (en) * | 2016-10-24 | 2017-03-22 | 广西智宝科技有限公司 | Crucian carp feed capable of preventing and treating branchia hyperemia disease and preparation method of crucian carp feed |
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Application publication date: 20130123 |