Summary of the invention
Technical problem to be solved by this invention is to provide a kind of fishing with antibacterial and anti-inflammation functions to use Chinese medicine composition.
Another technical problem to be solved by this invention is to provide above-mentioned method for preparing with fishing of antibacterial and anti-inflammation functions with Chinese medicine composition.
For solving the problems of the technologies described above, technical scheme of the present invention is:
Chinese medicine composition is used in a kind of fishing with antibacterial and anti-inflammation functions; Mainly form, count Radix Astragali 8.1-18.1 part, Rhizoma Atractylodis Macrocephalae 15-25 part, Radix Et Rhizoma Rhei 8.5-18.5 part, Cortex Magnoliae Officinalis 1.5-11.5 part, Radix Isatidis 28.5-38.5 part, Radix Glycyrrhizae 8.3-18.3 part by its parts by weight by the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Radix Et Rhizoma Rhei, Cortex Magnoliae Officinalis, Radix Isatidis and Radix Glycyrrhizae.
Preferably, Chinese medicine composition is used in above-mentioned fishing with antibacterial and anti-inflammation functions, by its parts by weight Radix Astragali 11-17 part, Rhizoma Atractylodis Macrocephalae 18-23 part, Radix Et Rhizoma Rhei 10-17 part, Cortex Magnoliae Officinalis 3-9 part, Radix Isatidis 30-37 part, Radix Glycyrrhizae 10-16 part.
Preferably, Chinese medicine composition is used in above-mentioned fishing with antibacterial and anti-inflammation functions, by 14 parts of its parts by weight Radixs Astragali, 20 parts of the Rhizoma Atractylodis Macrocephalaes, 14 parts of Radix Et Rhizoma Rhei, 7 parts of Cortex Magnoliae Officinalis, 33 parts of Radix Isatidis, 14 parts in Radix Glycyrrhizae.
Preferably; Chinese medicine composition is used in above-mentioned fishing with antibacterial and anti-inflammation functions; Also comprise phagostimulant, count Radix Astragali 8.1-18.1 part, Rhizoma Atractylodis Macrocephalae 15-25 part, Radix Et Rhizoma Rhei 8.5-18.5 part, Cortex Magnoliae Officinalis 1.5-11.5 part, Radix Isatidis 28.5-38.5 part, Radix Glycyrrhizae 8.3-18.3 part, phagostimulant 1-2 part by its parts by weight.
Preferably, Chinese medicine composition is used in above-mentioned fishing with antibacterial and anti-inflammation functions, and said phagostimulant is allicin powder or betanin.
Preferably, Chinese medicine composition is used in above-mentioned fishing with antibacterial and anti-inflammation functions, counts 14 parts of the Radixs Astragali, 21 parts of the Rhizoma Atractylodis Macrocephalaes, 14 parts of Radix Et Rhizoma Rhei, 7.5 parts of Cortex Magnoliae Officinalis, 35 parts of Radix Isatidis, 15 parts in Radix Glycyrrhizae, 1.5 parts of betanins by its parts by weight.
Above-mentioned method for preparing with fishing of antibacterial and anti-inflammation functions with Chinese medicine composition, concrete preparation process is following:
(1) taking by weighing Radix Astragali 8.1-18.1 part, Rhizoma Atractylodis Macrocephalae 15-25 part, Radix Et Rhizoma Rhei 8.5-18.5 part, Cortex Magnoliae Officinalis 1.5-11.5 part, Radix Isatidis 28.5-38.5 part, Radix Glycyrrhizae 8.3-18.3 part by weight is raw material;
(2) each flavor Chinese medicine is cleaned, dried, micronizing is to 30-60 μ m, and mix homogeneously promptly gets.
Preferably, above-mentioned method for preparing with fishing of antibacterial and anti-inflammation functions with Chinese medicine composition, concrete preparation process is following:
(1) taking by weighing Radix Astragali 8.1-18.1 part, Rhizoma Atractylodis Macrocephalae 15-25 part, Radix Et Rhizoma Rhei 8.5-18.5 part, Cortex Magnoliae Officinalis 1.5-11.5 part, Radix Isatidis 28.5-38.5 part, Radix Glycyrrhizae 8.3-18.3 part, phagostimulant 1-2 part by weight is raw material;
(2) each flavor Chinese medicine is cleaned, dried, micronizing is to 30-60 μ m, and mix homogeneously promptly gets.
Preferably, micronizing to 44 μ m in the above-mentioned method for preparing, said step (2) with fishing of antibacterial and anti-inflammation functions with Chinese medicine composition.
Above-mentioned fishing with antibacterial and anti-inflammation functions uses the consumption of Chinese medicine composition freely to eat in the normal feedstuff for according to the ratio of 1g/kg feedstuff said Chinese medicine composition being added to, and every day 2-3 time, logotype 3-5 days is a course of treatment.
The invention has the beneficial effects as follows:
Chinese medicine composition is used in above-mentioned fishing with antibacterial and anti-inflammation functions, with the Chinese medicine reasonable formula, has the effect of heat-clearing and toxic substances removing, anti-inflammation; Not only can effectively improve the individual resistance against diseases of fish and shrimp, inflammation-inhibiting takes place, and can strengthen the fish and shrimp immunologic function greatly simultaneously; And prescription is nontoxic, warm in nature and; Can in the fish and shrimp body, not produce residually, not produce drug resistance, can effectively be degraded by body; Its preparation method is simple, and cost is low, is fit to requirements of large-scale industrial production.
The specific embodiment
Below in conjunction with specific embodiment technical scheme according to the invention is further described.
Embodiment 1
Chinese medicine composition is used in a kind of fishing with antibacterial and anti-inflammation functions, is made up of the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Radix Et Rhizoma Rhei, Cortex Magnoliae Officinalis, Radix Isatidis and Radix Glycyrrhizae, and its weight is Radix Astragali 14kg, Rhizoma Atractylodis Macrocephalae 20kg, Radix Et Rhizoma Rhei 14kg, Cortex Magnoliae Officinalis 7kg, Radix Isatidis 33kg, Radix Glycyrrhizae 14kg.
Above-mentioned method for preparing with fishing of antibacterial and anti-inflammation functions with Chinese medicine composition, concrete preparation process is following:
(1) taking by weighing Radix Astragali 14kg, Rhizoma Atractylodis Macrocephalae 20kg, Radix Et Rhizoma Rhei 14kg, Cortex Magnoliae Officinalis 7kg, Radix Isatidis 33kg, Radix Glycyrrhizae 14kg is raw material;
(2) each flavor Chinese medicine is cleaned, dried, micronizing, smashing fineness is 44 μ m, mix homogeneously promptly gets.
Embodiment 2
Chinese medicine composition is used in a kind of fishing with antibacterial and anti-inflammation functions, is made up of the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Radix Et Rhizoma Rhei, Cortex Magnoliae Officinalis, Radix Isatidis and Radix Glycyrrhizae, and its weight is Radix Astragali 18.1kg, Rhizoma Atractylodis Macrocephalae 25kg, Radix Et Rhizoma Rhei 8.5kg, Cortex Magnoliae Officinalis 1.5kg, Radix Isatidis 28.5kg, Radix Glycyrrhizae 18.3kg.
Above-mentioned method for preparing with fishing of antibacterial and anti-inflammation functions with Chinese medicine composition, concrete preparation process is following:
(1) taking by weighing Radix Astragali 18.1kg, Rhizoma Atractylodis Macrocephalae 25kg, Radix Et Rhizoma Rhei 8.5kg, Cortex Magnoliae Officinalis 1.5kg, Radix Isatidis 28.5kg, Radix Glycyrrhizae 18.3kg is raw material;
(2) each flavor Chinese medicine is cleaned, dried, micronizing, smashing fineness is 30 μ m, mix homogeneously promptly gets.
Embodiment 3
Chinese medicine composition is used in a kind of fishing with antibacterial and anti-inflammation functions, is made up of the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Radix Et Rhizoma Rhei, Cortex Magnoliae Officinalis, Radix Isatidis and Radix Glycyrrhizae, and its weight is Radix Astragali 8.1kg, Rhizoma Atractylodis Macrocephalae 15kg, Radix Et Rhizoma Rhei 18.5kg, Cortex Magnoliae Officinalis 11.5kg, Radix Isatidis 38.5kg, Radix Glycyrrhizae 8.3kg.
Above-mentioned method for preparing with fishing of antibacterial and anti-inflammation functions with Chinese medicine composition, concrete preparation process is following:
(1) taking by weighing Radix Astragali 8.1kg, Rhizoma Atractylodis Macrocephalae 15kg, Radix Et Rhizoma Rhei 18.5kg, Cortex Magnoliae Officinalis 11.5kg, Radix Isatidis 38.5kg, Radix Glycyrrhizae 8.3kg is raw material;
(2) each flavor Chinese medicine is cleaned, dried, micronizing, smashing fineness is 60 μ m, mix homogeneously promptly gets.
Embodiment 4
Chinese medicine composition is used in a kind of fishing with antibacterial and anti-inflammation functions, is made up of the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Radix Et Rhizoma Rhei, Cortex Magnoliae Officinalis, Radix Isatidis and Radix Glycyrrhizae, and its weight is Radix Astragali 11kg, Rhizoma Atractylodis Macrocephalae 23kg, Radix Et Rhizoma Rhei 17kg, Cortex Magnoliae Officinalis 3kg, Radix Isatidis 30kg, Radix Glycyrrhizae 10kg.
Above-mentioned method for preparing with fishing of antibacterial and anti-inflammation functions with Chinese medicine composition, concrete preparation process is following:
(1) taking by weighing Radix Astragali 11kg, Rhizoma Atractylodis Macrocephalae 23kg, Radix Et Rhizoma Rhei 17kg, Cortex Magnoliae Officinalis 3kg, Radix Isatidis 30kg, Radix Glycyrrhizae 10kg is raw material;
(2) each flavor Chinese medicine is cleaned, dried, micronizing, smashing fineness is 52 μ m, mix homogeneously promptly gets.
Embodiment 5
Chinese medicine composition is used in a kind of fishing with antibacterial and anti-inflammation functions, is made up of the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Radix Et Rhizoma Rhei, Cortex Magnoliae Officinalis, Radix Isatidis and Radix Glycyrrhizae, and its weight is Radix Astragali 17kg, Rhizoma Atractylodis Macrocephalae 18kg, Radix Et Rhizoma Rhei 10kg, Cortex Magnoliae Officinalis 9kg, Radix Isatidis 37kg, Radix Glycyrrhizae 16kg.
Above-mentioned method for preparing with fishing of antibacterial and anti-inflammation functions with Chinese medicine composition, concrete preparation process is following:
(1) taking by weighing Radix Astragali 17kg, Rhizoma Atractylodis Macrocephalae 18kg, Radix Et Rhizoma Rhei 10kg, Cortex Magnoliae Officinalis 9kg, Radix Isatidis 37kg, Radix Glycyrrhizae 16kg is raw material;
(2) each flavor Chinese medicine is cleaned, dried, micronizing, smashing fineness is 35 μ m, mix homogeneously promptly gets.
Embodiment 6
Chinese medicine composition is used in a kind of fishing with antibacterial and anti-inflammation functions; Be made up of the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Radix Et Rhizoma Rhei, Cortex Magnoliae Officinalis, Radix Isatidis, Radix Glycyrrhizae and betanin, its weight is Radix Astragali 14kg, Rhizoma Atractylodis Macrocephalae 21kg, Radix Et Rhizoma Rhei 14kg, Cortex Magnoliae Officinalis 7.5kg, Radix Isatidis 35kg, Radix Glycyrrhizae 15kg, betanin 1.5kg.
Above-mentioned method for preparing with fishing of antibacterial and anti-inflammation functions with Chinese medicine composition, concrete preparation process is following:
(1) taking by weighing Radix Astragali 14kg, Rhizoma Atractylodis Macrocephalae 21kg, Radix Et Rhizoma Rhei 14kg, Cortex Magnoliae Officinalis 7.5kg, Radix Isatidis 35kg, Radix Glycyrrhizae 15kg, betanin 1.5kg is raw material;
(2) each flavor Chinese medicine is cleaned, dried, micronizing, smashing fineness is 47 μ m, mix homogeneously promptly gets.
Embodiment 7
Chinese medicine composition is used in a kind of fishing with antibacterial and anti-inflammation functions; Be made up of the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Radix Et Rhizoma Rhei, Cortex Magnoliae Officinalis, Radix Isatidis, Radix Glycyrrhizae and allicin powder, its weight is Radix Astragali 15kg, Rhizoma Atractylodis Macrocephalae 24kg, Radix Et Rhizoma Rhei 15kg, Cortex Magnoliae Officinalis 11kg, Radix Isatidis 30kg, Radix Glycyrrhizae 18kg, allicin powder 1.4kg.
Above-mentioned method for preparing with fishing of antibacterial and anti-inflammation functions with Chinese medicine composition, concrete preparation process is following:
(1) taking by weighing Radix Astragali 15kg, Rhizoma Atractylodis Macrocephalae 24kg, Radix Et Rhizoma Rhei 15kg, Cortex Magnoliae Officinalis 11kg, Radix Isatidis 30kg, Radix Glycyrrhizae 18kg, allicin powder 1.4kg is raw material;
(2) each flavor Chinese medicine is cleaned, dried, micronizing, smashing fineness is 39 μ m,, mix homogeneously promptly gets.
Embodiment 8
Chinese medicine composition is used in a kind of fishing with antibacterial and anti-inflammation functions; Be made up of the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Radix Et Rhizoma Rhei, Cortex Magnoliae Officinalis, Radix Isatidis, Radix Glycyrrhizae and betanin, its weight is Radix Astragali 15kg, Rhizoma Atractylodis Macrocephalae 21kg, Radix Et Rhizoma Rhei 9kg, Cortex Magnoliae Officinalis 2kg, Radix Isatidis 38kg, Radix Glycyrrhizae 9kg, betanin 1kg.
Above-mentioned method for preparing with fishing of antibacterial and anti-inflammation functions with Chinese medicine composition, concrete preparation process is following:
(1) taking by weighing Radix Astragali 15kg, Rhizoma Atractylodis Macrocephalae 21kg, Radix Et Rhizoma Rhei 9kg, Cortex Magnoliae Officinalis 2kg, Radix Isatidis 38kg, Radix Glycyrrhizae 9kg, betanin 1kg is raw material;
(2) each flavor Chinese medicine is cleaned, dried, micronizing, smashing fineness is 56 μ m,, mix homogeneously promptly gets.
Each amounts of components of the said Chinese crude drug of one of embodiment 1-8 is increased or reduces according to same ratio, and the parts by weight relation of each component of gained all belongs to protection scope of the present invention.
The said Chinese crude drug of embodiment 1-8 all meets " Chinese veterinary drug allusion quotation " version two ministerial standards in 2005.
The composition principle of Chinese medicine composition according to the invention is: Radix Astragali sweet in the mouth is warm in nature, is important QI invigorating Chinese medicine, has the effect of QI invigorating benefit table, detoxification granulation promoting, wherein contains plurality of active ingredients such as polysaccharide, osajin and Saponin class; The ability anticoagulant reduces blood viscosity and coagulability, strengthens plasmin activity, relaxing smooth muscle; Expansion lung, the heart, cerebrovascular reduce vascular resistance, improve blood circulation; Especially microcirculation improvement, thus cardio-pulmonary function improved, promote pulmonary ventilation, organization aeration; The Radix Astragali can effectively reduce lipid peroxidation, reduces the generation of malonaldehyde, and the effect of stronger removing free radical is arranged, and the effective ingredient astragaloside of the Radix Astragali has effects such as antiinflammatory, calmness, analgesia; The Radix Astragali and Cortex Magnoliae Officinalis, the Rhizoma Atractylodis Macrocephalae, Radix Isatidis four flavor Chinese medicines have the effect that negative and positive were set upright, regulated to tonify deficiency; The Radix Astragali and Radix Glycyrrhizae, Radix Et Rhizoma Rhei three flavor Chinese medicines have the effect of heat-clearing and toxic substances removing, anti-inflammation.Full side's Synergistic; Effect with anti-inflammation; Improve culturing fish and shrimp body nonspecific immunity function simultaneously, improve its disease-resistant bacterium ability, and dosage is little, is applicable to the control of fish and shrimp common bacteria virosis; Especially adopt embodiment 1 said proportioning control liver and gallbladder syndrome, adopt the effect of embodiment 6 said proportioning control bacterial enteritiss very remarkable.
The clinical trial example:
Adopt embodiment 1 said Chinese medicine composition in the Hunan plant do test when participating in the cintest, be used to treat the syndromic effect observation of speckle fork-tail silver xenocypris liver and gall.
Have the speckle fork-tail silver xenocypris phase secondary disease of more than 30 mouthful of cage culture in June, 2011, their early stage, and the external sight of fish is more normal, and it is transparent to examine visible tail fin edge, is commonly called as " fringing "; Fish swimming is undesired; Dissect that visible gallbladder is bigger than normal, bile is denseer, the liver enlargement, red and white, be graniphyric or bleach; And with symptomes complices such as enteritis, hemorrhage, ulcer, the serious fish hepatic necrosis abscess of falling ill or be bean curd slag specimen pathological changes is liver and gall syndrome of fish after diagnosing.
The embodiment of the invention 1 said Chinese medicine composition is added in the fish normal feedstuff (available from Tianjin rainbow feed corporation,Ltd) with the mode that the per kilogram feedstuff adds the 1g Chinese medicine composition; Throw something and feed every day 3 times; Using 3 days continuously is a course of treatment; The silver xenocypris fish is dead after the medication obviously reduces, and reduces in ten tails from dead 60 tails of beginning every mouthful of net cage every day, use a course of treatment after the phenomena of mortality stop.A Zhou Houzai throws something and feeds a course of treatment at interval, and the after treatment effect strengthens the Fish Abwehrkraft des Koepers, and this type of disease does not take place in the net cage then once more, has played good prevention effect.
The effect comparison test:
Effect comparison test is done by plant in Tianjin, the bacterial enteritis that is used to treat fish, and main clinic symptoms shows as: slow in action, do not ingest, abdominal distension, anus is outstanding, redness etc.Get the sick fish of equivalent and make an experiment, the embodiment of the invention 6 said Chinese medicine composition and norfloxacin in treatment are used in test respectively.
The Chinese medicine composition group is added in the fish normal feedstuff (available from Tianjin rainbow feed corporation,Ltd) with the mode that the per kilogram feedstuff adds the 1g Chinese medicine composition, every fish daily ration of throwing something and feeding 3 times every day, and dosage used 3 days continuously first; Norfloxacin (10%) group is thrown something and fed 3 times (300mg/d) every day, uses continuously 3 days.
Use Chinese medicine composition group effective percentage to reach 94.3% after the course of treatment, cure rate reaches 81.5%; Norfloxacin (10%) experimental group effective percentage is 71%, and cure rate is 66.2%.
Above-mentioned detailed description of this a kind of fishing with antibacterial and anti-inflammation functions being carried out with Chinese medicine composition and preparation method thereof with reference to embodiment; Be illustrative rather than determinate; Can enumerate out several embodiment according to institute's limited range; Therefore in the variation and the modification that do not break away under the general plotting of the present invention, should belong within protection scope of the present invention.