Summary of the invention
Technical problem to be solved by this invention is to provide a kind of fishing Chinese medicine composition with Anti-bacterium effect.
Another technical problem to be solved by this invention is to provide the above-mentioned preparation method of the fishing of Anti-bacterium effect with Chinese medicine composition that have.
For solving the problems of the technologies described above, technical scheme of the present invention is:
A kind of fishing Chinese medicine composition with Anti-bacterium effect, mainly by the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Radix Et Rhizoma Rhei, Cortex Magnoliae Officinalis, Radix Isatidis, Radix Glycyrrhizae and Herba Taraxaci, formed, by its parts by weight, count Radix Astragali 30-36 part, Rhizoma Atractylodis Macrocephalae 10-16 part, Radix Et Rhizoma Rhei 10-16 part, Cortex Magnoliae Officinalis 4-10 part, Radix Isatidis 10-16 part, Radix Glycyrrhizae 4-10 part, Herba Taraxaci 10-16 part.
Preferably, the above-mentioned fishing Chinese medicine composition with Anti-bacterium effect, by its parts by weight Radix Astragali 32-34 part, Rhizoma Atractylodis Macrocephalae 12-15 part, Radix Et Rhizoma Rhei 12-14 part, Cortex Magnoliae Officinalis 5-7.8 part, Radix Isatidis 12-15 part, Radix Glycyrrhizae 5-8 part, Herba Taraxaci 12.5-15 part.
Preferably, the above-mentioned fishing Chinese medicine composition with Anti-bacterium effect, by 33.3 parts of its parts by weight Radixs Astragali, 14 parts of the Rhizoma Atractylodis Macrocephalaes, 13 parts of Radix Et Rhizoma Rhei, 6.6 parts of Cortex Magnoliae Officinalis, 13.8 parts of Radix Isatidis, 7 parts, Radix Glycyrrhizae, 14.5 parts of Herba Taraxacis.
Preferably, the above-mentioned fishing Chinese medicine composition with Anti-bacterium effect, also comprise phagostimulant, by its parts by weight, count Radix Astragali 30-36 part, Rhizoma Atractylodis Macrocephalae 10-16 part, Radix Et Rhizoma Rhei 10-16 part, Cortex Magnoliae Officinalis 4-10 part, Radix Isatidis 10-16 part, Radix Glycyrrhizae 4-10 part, Herba Taraxaci 10-16 part, phagostimulant 1-2 part.
Preferably, the above-mentioned fishing Chinese medicine composition with Anti-bacterium effect, described phagostimulant is allicin powder or betanin.
Preferably, the above-mentioned fishing Chinese medicine composition with Anti-bacterium effect, count 33 parts of the Radixs Astragali, 13 parts of the Rhizoma Atractylodis Macrocephalaes, 13.6 parts of Radix Et Rhizoma Rhei, 5.7 parts of Cortex Magnoliae Officinalis, 13 parts of Radix Isatidis, 6 parts, Radix Glycyrrhizae, 14 parts of Herba Taraxacis, 1.5 parts of betanins by its parts by weight.
The above-mentioned fishing with the Anti-bacterium effect preparation method of Chinese medicine composition, concrete preparation process is as follows:
(1) taking by weight Radix Astragali 30-36 part, Rhizoma Atractylodis Macrocephalae 10-16 part, Radix Et Rhizoma Rhei 10-16 part, Cortex Magnoliae Officinalis 4-10 part, Radix Isatidis 10-16 part, Radix Glycyrrhizae 4-10 part, Herba Taraxaci 10-16 part is raw material;
(2) each flavor Chinese medicine is cleaned, dried, micronizing is to 30-60 μ m, and mix homogeneously, obtain.
Preferably, the above-mentioned fishing with the Anti-bacterium effect preparation method of Chinese medicine composition, concrete preparation process is as follows:
(1) taking by weight Radix Astragali 30-36 part, Rhizoma Atractylodis Macrocephalae 10-16 part, Radix Et Rhizoma Rhei 10-16 part, Cortex Magnoliae Officinalis 4-10 part, Radix Isatidis 10-16 part, Radix Glycyrrhizae 4-10 part, Herba Taraxaci 10-16 part, phagostimulant 1-2 part is raw material;
(2) each flavor Chinese medicine is cleaned, dried, micronizing is to 30-60 μ m, and mix homogeneously, obtain.
Preferably, the above-mentioned fishing with the Anti-bacterium effect preparation method of Chinese medicine composition, micronizing to 44 μ m in described step (2).
The above-mentioned fishing with Anti-bacterium effect freely eats in 1 ‰ ratio, described Chinese medicine composition being added in normal feedstuff with the consumption of Chinese medicine composition, and every day 2-3 time, being used in conjunction 3-5 days is a course for the treatment of.
The invention has the beneficial effects as follows:
The above-mentioned fishing Chinese medicine composition with Anti-bacterium effect, by the Chinese medicine reasonable formula, there is the effect of holding up empty revisal, regulating negative and positive, heat-clearing and toxic substances removing, anti-inflammation, when improving the fish and shrimp immunocompetence, greatly improve the ability of its Anti-bacterium, thereby effectively protect the fish and shrimp individuality, and prescription is nontoxic, warm in nature and, can in the fish and shrimp body, not produce residually, not produce drug resistance, can effectively be degraded by body; Its preparation method is simple, and cost is low, is applicable to the needs that large-scale industrial is produced.
The specific embodiment
Below in conjunction with specific embodiment, technical scheme of the present invention is further described.
Embodiment 1
A kind of fishing Chinese medicine composition with Anti-bacterium effect, the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Radix Et Rhizoma Rhei, Cortex Magnoliae Officinalis, Radix Isatidis, Radix Glycyrrhizae and Herba Taraxaci, consist of, its weight is Radix Astragali 33.3kg, Rhizoma Atractylodis Macrocephalae 14kg, Radix Et Rhizoma Rhei 13kg, Cortex Magnoliae Officinalis 6.6kg, Radix Isatidis 13.8kg, Radix Glycyrrhizae 7kg, Herba Taraxaci 14.5kg.
The above-mentioned fishing with the Anti-bacterium effect preparation method of Chinese medicine composition, concrete preparation process is as follows:
(1) take Radix Astragali 33.3kg, Rhizoma Atractylodis Macrocephalae 14kg, Radix Et Rhizoma Rhei 13kg, Cortex Magnoliae Officinalis 6.6kg, Radix Isatidis 13.8kg, Radix Glycyrrhizae 7kg, Herba Taraxaci 14.5kg is raw material;
(2) each flavor Chinese medicine is cleaned, dried, micronizing, smashing fineness is 44 μ m, mix homogeneously, obtain.
Embodiment 2
A kind of fishing Chinese medicine composition with Anti-bacterium effect, the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Radix Et Rhizoma Rhei, Cortex Magnoliae Officinalis, Radix Isatidis, Radix Glycyrrhizae and Herba Taraxaci, consist of, its weight is Radix Astragali 32kg, Rhizoma Atractylodis Macrocephalae 15kg, Radix Et Rhizoma Rhei 12kg, Cortex Magnoliae Officinalis 5kg, Radix Isatidis 12kg, Radix Glycyrrhizae 8kg, Herba Taraxaci 15kg.
The above-mentioned fishing with the Anti-bacterium effect preparation method of Chinese medicine composition, concrete preparation process is as follows:
(1) take Radix Astragali 32kg, Rhizoma Atractylodis Macrocephalae 15kg, Radix Et Rhizoma Rhei 12kg, Cortex Magnoliae Officinalis 5kg, Radix Isatidis 12kg, Radix Glycyrrhizae 8kg, Herba Taraxaci 15kg is raw material;
(2) each flavor Chinese medicine is cleaned, dried, micronizing, smashing fineness is 30 μ m, mix homogeneously, obtain.
Embodiment 3
A kind of fishing Chinese medicine composition with Anti-bacterium effect, the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Radix Et Rhizoma Rhei, Cortex Magnoliae Officinalis, Radix Isatidis, Radix Glycyrrhizae and Herba Taraxaci, consist of, its weight is Radix Astragali 34kg, Rhizoma Atractylodis Macrocephalae 12kg, Radix Et Rhizoma Rhei 14kg, Cortex Magnoliae Officinalis 7.8kg, Radix Isatidis 15kg, Radix Glycyrrhizae 5kg, Herba Taraxaci 12.5kg.
The above-mentioned fishing with the Anti-bacterium effect preparation method of Chinese medicine composition, concrete preparation process is as follows:
(1) take Radix Astragali 34kg, Rhizoma Atractylodis Macrocephalae 12kg, Radix Et Rhizoma Rhei 14kg, Cortex Magnoliae Officinalis 7.8kg, Radix Isatidis 15kg, Radix Glycyrrhizae 5kg, Herba Taraxaci 12.5kg is raw material;
(2) each flavor Chinese medicine is cleaned, dried, micronizing, smashing fineness is 60 μ m, mix homogeneously, obtain.
Embodiment 4
A kind of fishing Chinese medicine composition with Anti-bacterium effect, the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Radix Et Rhizoma Rhei, Cortex Magnoliae Officinalis, Radix Isatidis, Radix Glycyrrhizae and Herba Taraxaci, consist of, its weight is Radix Astragali 36kg, Rhizoma Atractylodis Macrocephalae 10kg, Radix Et Rhizoma Rhei 10kg, Cortex Magnoliae Officinalis 10kg, Radix Isatidis 16kg, Radix Glycyrrhizae 4kg, Herba Taraxaci 16kg.
The above-mentioned fishing with the Anti-bacterium effect preparation method of Chinese medicine composition, concrete preparation process is as follows:
(1) take Radix Astragali 36kg, Rhizoma Atractylodis Macrocephalae 10kg, Radix Et Rhizoma Rhei 10kg, Cortex Magnoliae Officinalis 10kg, Radix Isatidis 16kg, Radix Glycyrrhizae 4kg, Herba Taraxaci 16kg is raw material;
(2) each flavor Chinese medicine is cleaned, dried, micronizing, smashing fineness is 52 μ m, mix homogeneously, obtain.
Embodiment 5
A kind of fishing Chinese medicine composition with Anti-bacterium effect, the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Radix Et Rhizoma Rhei, Cortex Magnoliae Officinalis, Radix Isatidis, Radix Glycyrrhizae and Herba Taraxaci, consist of, its weight is Radix Astragali 33kg, Rhizoma Atractylodis Macrocephalae 13kg, Radix Et Rhizoma Rhei 14kg, Cortex Magnoliae Officinalis 7kg, Radix Isatidis 14kg, Radix Glycyrrhizae 8kg, Herba Taraxaci 14kg.
The above-mentioned fishing with the Anti-bacterium effect preparation method of Chinese medicine composition, concrete preparation process is as follows:
(1) take Radix Astragali 33kg, Rhizoma Atractylodis Macrocephalae 13kg, Radix Et Rhizoma Rhei 14kg, Cortex Magnoliae Officinalis 7kg, Radix Isatidis 14kg, Radix Glycyrrhizae 8kg, Herba Taraxaci 14kg is raw material;
(2) each flavor Chinese medicine is cleaned, dried, micronizing, smashing fineness is 35 μ m, mix homogeneously, obtain.
Embodiment 6
A kind of fishing Chinese medicine composition with Anti-bacterium effect, the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Radix Et Rhizoma Rhei, Cortex Magnoliae Officinalis, Radix Isatidis, Radix Glycyrrhizae, Herba Taraxaci and betanin, consist of, its weight is Radix Astragali 33kg, Rhizoma Atractylodis Macrocephalae 13kg, Radix Et Rhizoma Rhei 13.6kg, Cortex Magnoliae Officinalis 5.7kg, Radix Isatidis 13kg, Radix Glycyrrhizae 6kg, Herba Taraxaci 14kg, betanin 1.5kg.
The above-mentioned fishing with the Anti-bacterium effect preparation method of Chinese medicine composition, concrete preparation process is as follows:
(1) take Radix Astragali 33kg, Rhizoma Atractylodis Macrocephalae 13kg, Radix Et Rhizoma Rhei 13.6kg, Cortex Magnoliae Officinalis 5.7kg, Radix Isatidis 13kg, Radix Glycyrrhizae 6kg, Herba Taraxaci 14kg, betanin 1.5kg are raw material;
(2) each flavor Chinese medicine is cleaned, dried, micronizing, smashing fineness is 47 μ m, mix homogeneously, obtain.
Embodiment 7
A kind of fishing Chinese medicine composition with Anti-bacterium effect, the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Radix Et Rhizoma Rhei, Cortex Magnoliae Officinalis, Radix Isatidis, Radix Glycyrrhizae, Herba Taraxaci and allicin powder, consist of, its weight is Radix Astragali 30kg, Rhizoma Atractylodis Macrocephalae 16kg, Radix Et Rhizoma Rhei 16kg, Cortex Magnoliae Officinalis 4kg, Radix Isatidis 10kg, Radix Glycyrrhizae 10kg, Herba Taraxaci 10kg, allicin powder 2kg.
The above-mentioned fishing with the Anti-bacterium effect preparation method of Chinese medicine composition, concrete preparation process is as follows:
(1) take Radix Astragali 30kg, Rhizoma Atractylodis Macrocephalae 16kg, Radix Et Rhizoma Rhei 16kg, Cortex Magnoliae Officinalis 4kg, Radix Isatidis 10kg, Radix Glycyrrhizae 10kg, Herba Taraxaci 10kg, allicin powder 2kg are raw material;
(2) each flavor Chinese medicine is cleaned, dried, micronizing, smashing fineness is 39 μ m, mix homogeneously, obtain.
Embodiment 8
A kind of fishing Chinese medicine composition with Anti-bacterium effect, the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Radix Et Rhizoma Rhei, Cortex Magnoliae Officinalis, Radix Isatidis, Radix Glycyrrhizae, Herba Taraxaci and betanin, consist of, its weight is Radix Astragali 35kg, Rhizoma Atractylodis Macrocephalae 13kg, Radix Et Rhizoma Rhei 11kg, Cortex Magnoliae Officinalis 6kg, Radix Isatidis 13kg, Radix Glycyrrhizae 7kg, Herba Taraxaci 13.5kg, betanin 1kg.
The above-mentioned fishing with the Anti-bacterium effect preparation method of Chinese medicine composition, concrete preparation process is as follows:
(1) take Radix Astragali 35kg, Rhizoma Atractylodis Macrocephalae 13kg, Radix Et Rhizoma Rhei 11kg, Cortex Magnoliae Officinalis 6kg, Radix Isatidis 13kg, Radix Glycyrrhizae 7kg, Herba Taraxaci 13.5kg, betanin 1kg are raw material;
(2) each flavor Chinese medicine is cleaned, dried, micronizing, smashing fineness is 56 μ m, mix homogeneously, obtain.
Each amounts of components of the described Chinese crude drug of one of embodiment 1-8 is increased or reduces according to same ratio, and the parts by weight relation of each component of gained all belongs to protection scope of the present invention.
The described Chinese crude drug of embodiment 1-8 all meets " Chinese veterinary pharmacopoeia " version two ministerial standards in 2005.
The composition principle of Chinese medicine composition of the present invention is: Radix Astragali sweet in the mouth is warm in nature, is important QI invigorating Chinese medicine, has the effect of QI invigorating benefit table, detoxification granulation promoting, wherein contain the plurality of active ingredients such as polysaccharide, osajin and Saponin class, the energy anticoagulant, reduce blood viscosity and coagulability, strengthen plasmin activity, relaxing smooth muscle, expansion lung, the heart, cerebrovascular, reduce vascular resistance, improve blood circulation, especially improve microcirculation, thereby improve cardio-pulmonary function, promote pulmonary ventilation, organization aeration; The Radix Astragali can effectively reduce lipid peroxidation, reduces the generation of malonaldehyde, and the effect of stronger removing free radical is arranged, and the effective ingredient astragaloside of the Radix Astragali has the effects such as antiinflammatory, calmness, analgesia; The Radix Astragali and Cortex Magnoliae Officinalis, the Rhizoma Atractylodis Macrocephalae, Radix Isatidis four flavor Chinese medicines have the tonify deficiency righting, regulate the effect of negative and positive; The Radix Astragali and Radix Glycyrrhizae, Radix Et Rhizoma Rhei, Herba Taraxaci four flavor Chinese medicines have the effect of heat-clearing and toxic substances removing, anti-inflammation.Full side's Synergistic, there are the characteristics such as improve culturing fish and shrimp body nonspecific immunity function, improve its Anti-bacterium ability, dosage is little, be applicable to the control of fish and shrimp common bacteria virosis, especially adopt embodiment 1 and the described proportioning of embodiment 6, very remarkable for the effect of preventing and treating bacterial enteritis.
Clinical trial example 1:
Adopt the described Chinese medicine composition of embodiment 1 to do test when participating in the cintest in Tianjin plant.
Be used for the treatment of the flower silver carp bacterial enteritis comprehensively sick, sick fish performance: slow in action, do not ingest, abdominal distension, anus is outstanding, red and swollen.Press abdominal part with have gentle hands, have yellow mucus to flow out from anus.Open the abdominal cavity of disease fish, visible intestinal wall hyperemia, be bronzing, and enteral does not have food, only has much flaxen mucus, and the fishpond mortality rate is 5%.
The described Chinese medicine composition of the embodiment of the present invention 1 is added in the fish normal feedstuff purchased from Tianjin rainbow feed corporation,Ltd with 1 ‰ addition, throw something and feed every day 3 times, use continuously 3 days, after the course for the treatment of, treated effect reaches 85-90%, dead fish phenomenon do not occur.
Clinical trial example 2:
For the fish body of suffering from the Ietalurus Punetaus virosis, sick fish performance: sick fish skin skin and fin base portion are hemorrhage, abdominal distension, and faint yellow transudate (ascites) is arranged.The gill is pale or hemorrhage, a side or bilateral exophthalmos.Dissect inspection and can see that muscular tissue, liver, kidney and spleen have hemorrhage district.Spleen is light red and enlargement; Stomach expands mucosa shape secretions.The intestinal canescence, without food, the sick fish mortality rate in fishpond is 9%.
The described Chinese medicine composition of the embodiment of the present invention 1 is added in the fish normal feedstuff purchased from Tianjin rainbow feed corporation,Ltd with 1 ‰ addition, throw something and feed every day 3 times, use continuously 3 days, after the course for the treatment of, mortality rate no longer increases, the basic controlling state of an illness.
Piglet s colibacillosis:
In Tianjin, Piglet s colibacillosis is done by plant, is used for the treatment of the bacterial enteritis of fish, and main clinic symptoms shows as: slow in action, do not ingest, and abdominal distension, anus is outstanding, red and swollen etc.Get the sick fish of equivalent and tested, the described Chinese medicine composition of the embodiment of the present invention 6 and norfloxacin in treatment are used respectively in test.
The Chinese medicine composition group is added in the fish normal feedstuff purchased from Tianjin rainbow feed corporation,Ltd with 1 ‰ addition, every fish daily ration of throwing something and feeding 3 times every day, and dosage, used 3 days continuously first; Norfloxacin (10%) group is thrown something and fed 3 times (300mg/d) every day, uses continuously 3 days.
After the course for the treatment of, use Chinese medicine composition group effective percentage to reach 91.2%, cure rate reaches 79%; Norfloxacin (10%) experimental group effective percentage is 70%, and cure rate is 63.2%.
Above-mentioned detailed description of this kind of fishing with Anti-bacterium effect being carried out with Chinese medicine composition and preparation method thereof with reference to embodiment; illustrative rather than determinate; can list several embodiment according to institute's limited range; therefore in the variation and the modification that do not break away under general plotting of the present invention, within should belonging to protection scope of the present invention.