CN102626499B - Traditional Chinese medicinal composition used as both food and medicine for treating porcine respiratory tract infection, and preparation method thereof - Google Patents
Traditional Chinese medicinal composition used as both food and medicine for treating porcine respiratory tract infection, and preparation method thereof Download PDFInfo
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Abstract
The invention relates to a traditional Chinese medicinal composition used as both food and medicine for treating porcine respiratory tract infection, and a preparation method thereof. The medicinal composition comprises, by weight, 100 to 120 parts of cordate houttuynia, 40 to 60 parts of pyrrosia leaf, 40 to 60 parts of perilla fruit, 120 to 140 parts of gypsum, 40 to 60 parts of white mustard seed, 15 to 35 parts of licorice, 40 to 60 parts of aster, 40 to 60 parts of radix stemonae, 40 to 60 parts of platycodon grandiflorum, 100 to 120 parts of semen raphani, and 15 to 35 parts of herba ephedrae. All the above raw materials are prepared according to the weight proportion, and ground into fine powder to be mixed in pig feed to feed pigs. The traditional Chinese medicinal composition provided by the invention mainly cures diseases with the main symptoms of cough and asthma caused by porcine respiratory tract infection, has the advantages of fast curative effect, short course of treatment, no recurrence, and no toxic side effect, and the total effective rate is more than 99%.
Description
Technical field
The invention belongs to treatment animal disease medicine, particularly relate to a kind of with the Chinese herbal medicine be feedstock production be used for the treatment of Chinese medicine powder of respiratory tract infection of pigs and preparation method thereof.
Technical background
Swine enzootic pneumonia belongs to commonly encountered diseases, frequently-occurring disease at veterinary clinic, is to cause one of pig main causes of death.Due to mainly being infected by mycoplasma, antibacterial etc.; This condition of disease causes that the inappetence of pig, the price of deed reduce, growth retardation.Clinically antibiotic is used in the treatment of this disease usually, as: medicines such as kanamycin, streptomycin, oxytetracycline, lincomycin, ivermectin; And the propagation of encountered pathogenic bacteria fastbacteria makes a lot of antibiotic DeGrain when the treatment relevant disease, the normal wrong treatment behavior that causes people's overdose, cause bacterial drug resistance to strengthen or a large amount of appearance of dissociant and increased the weight of the propagation of cause of disease fastbacteria, cause tremendous influence and serious threat the healthy of people to animal husbandry production; Have with antibiotic therapy swine enzootic pneumonia existing questions: the one, easily produce drug resistance, toxicity and take effect recovery slowly, the 2nd, the medicine valency is higher, is difficult to apply.For this reason, the treatment by Chinese herbs swine enzootic pneumonia is attempted to use in this area, but the Chinese medicine great majority that can treat asthma up to now are Chinese medicine and western medicine mixing medicines, though certain curative effect is arranged clinically, but curative effect is low and what really play conclusive effect is Chinese medicine or Western medicine on earth, still lack at present the examination of scientific and precise, because all combination medicines all can direct or indirect Zhichuan in its prescription.As: publication number CN101690758A, denomination of invention " compound datura flower asthma relieving powder and the preparation method that are used for the treatment of respiratory tract infection of pigs ".The prescription that has in addition can only merely be used for the treatment of the asthma of pig, can not be used for the treatment of other reasons asthma and cough, so range of application clinically is restricted.
At present this type of disease of control in, Western medicine product often all be lay particular stress on treat and effect single, though also can solve some problems, but balance and the rapport of having ignored the endo globality of disease and relevant organ dysfunction, and therefore cover other problems or even question of substance, and then cause more serious consequence easily.
Summary of the invention
At above-mentioned deficiency, the invention provides a kind of pure Chinese prescription, the asthma and cough that a variety of causes is caused all has the medicinal and edible Chinese medicine composition and method of making the same of the treatment respiratory tract infection of pigs of significant curative effect.
The technical solution used in the present invention is: a kind of Chinese medicine composition for the treatment of the medicine-food two-purpose of respiratory tract infection of pigs, the component of said composition and each composition weight umber are: Herba Houttuyniae 100-120 part, Folium Pyrrosiae 40-60 part, Fructus Perillae 40-60 part, Gypsum Fibrosum 120-140 part, Semen Sinapis Albae 40-60 part, Radix Glycyrrhizae 15-35 part, Radix Asteris 40-60 part, Radix Stemonae 40-60 part, Radix Platycodonis 40-60 part, Semen Raphani 100-120 part, Herba Ephedrae 15-35 part.
A kind of preparation method of Chinese medicine composition of medicine-food two-purpose for the treatment of respiratory tract infection of pigs may further comprise the steps:
(1) choose the measured crude drug of matter by said components, the water content in the crude drug is lower than 10%, and by weight the crude drug of choosing is weighed up, and is standby;
(2) crude drug that weighs up is mixed;
(3) batch mixing that mixes is put into pulverizer and pulverizes, be ground into can be all coarse powder by the 100-120 mesh sieve;
(4) mix with mixer, the medicine that mixes is carried out drying;
(5) with dried drug packages, airtight preservation.
Chinese medicinal ingredients pharmacology of the present invention is: Herba Houttuyniae, Gypsum Fibrosum, Radix Glycyrrhizae have the effect of heat-clearing and toxic substances removing, lung qi dispersing relieving cough and resolving phlegm, and be effective to various bacteria, the mycoplasma that causes respiratory tract infection of pigs; Folium Pyrrosiae, Fructus Perillae, the Radix Stemonae have that clearing away lung-heat to relieve cough is relievingd asthma, therapeutic method to keep the adverse QI flowing downwards expectorant, treating acute and chronic tracheitis, bronchitis, pneumonia; Semen Sinapis Albae, Herba Ephedrae have warming the lung to eliminate phlegm, expelling pathogenic factors from muscles for clearing heat, removing obstruction in the collateral to relieve pain, cure mainly that rapid breathing, cough are breathed hard, diseases such as fullness in the chest vexedly expands, the twinge of the breast side of body, asthma; Radix Asteris,, Radix Platycodonis, Semen Raphani has clearing away heat from the throat and easing the chest, lowering the adverse-rising QI to relieve dyspnea, cures mainly that laryngopharynx swelling and pain, hypochondriac pain uncomfortable in chest, lung abscess are coughed and told, the feeling of fullness QI rising in reverse order.
Chinese veterinarian's polarization: this disease belongs to due to visceral-qi weakness, exopathogen invasion, attack of pathogenic warmth in the lung, improper diet, the disorder of emotion etc.; Attack of pathogenic warmth in the lung, then dyspnea, cough panted or is irregular breathing.
Chinese medicine composition of the present invention has been broken and traditional has been controlled the Therapeutic Method of breathing heavily to breathe heavily, and equilibrium between yin and yang and the histotrophic nutrition situation by regulating body, improve natural endowment deficiency, impairment of purifying and descending function of the lung and air flue contraction are anxious etc. reaches the purpose of heat-clearing and toxic substances removing, warming the lung to eliminate phlegm, lung heat clearing Zhichuan, removing obstruction in the collateral to relieve pain, clearing away heat from the throat and easing the chest, lowering the adverse-rising QI to relieve dyspnea.This Chinese medicine composition reaches more than 99% the effective percentage of swine enzootic pneumonia, uses this medicine and can exempt to be particularly useful for the case of antibiotic therapy DeGrain with other all antibacterials.Demonstrated fully organic conception and the advantage of Chinese medicine, made drug effect and function more comprehensive and treating both the principal and secondary aspects of a disease is debated concrete intension and the range of application that disease executing controlled thereby opened up out Chinese medicine.
Chinese medicine is abundant in china natural resources, applicating history is long, cheap, and has many-sided effect such as antibiotic, antiviral, antitoxin, immunomodulating and raising fertility performance, and toxic and side effects is little, aspect the treatment swine enzootic pneumonia, can match in excellence or beauty with antibiotic with the advantage of its many-sided effect, there is not the drug resistance problem.In animal husbandry is produced as antibiotic succedaneum, at nutrition, health care, raising immunity, anti-stress, antioxidation with improve many-sided application such as livestock products quality and more and more be subject to people's attention.And traditional piglet is arrested injection, not only labor intensity is big, also easily sick pig is caused various stress; Chinese medicine is fed the easy saving of labor of dispensing, safety material benefit, short treating period, curative effect height, protective rate height, has been overcome the difficulty of the perfusion of having an injection, and is easy to promote aborning.
The specific embodiment
Embodiment 1
A kind of medicinal and edible Chinese medicine compositions for the treatment of respiratory tract infection of pigs, its medical material is formed and percentage by weight is: 100 parts of Herba Houttuyniae, 40 parts of Folium Pyrrosiaes, 40 parts of Fructus Perillaes, 120 parts of Gypsum Fibrosum, 40 parts of Semen Sinapis Albaes, 15 parts in Radix Glycyrrhizae, 40 parts of Radix Asteriss, 40 parts of the Radixs Stemonae, 40 parts of Radix Platycodoniss, 100 parts of Semen Raphanis, 15 parts in Herba Ephedrae.
The preparation technology of this enforcement is: choose the measured crude drug of above-mentioned matter, the water content in the crude drug is lower than 10%, and by weight percentage the crude drug of choosing is weighed up, and is standby.Then the crude drug that weighs up is mixed and puts into pulverizer and pulverize, be ground into can be all coarse powder by 100 mesh sieves; And with the mixer mixing, again the medicine that mixes is carried out drying; With dried drug packages, airtight preservation pack.
Embodiment 2
A kind of medicinal and edible Chinese medicine compositions for the treatment of respiratory tract infection of pigs, its medical material is formed and percentage by weight is: 110 parts of Herba Houttuyniae, 50 parts of Folium Pyrrosiaes, 50 parts of Fructus Perillaes, 130 parts of Gypsum Fibrosum, 50 parts of Semen Sinapis Albaes, 20 parts in Radix Glycyrrhizae, 50 parts of Radix Asteriss, 50 parts of the Radixs Stemonae, 50 parts of Radix Platycodoniss, 110 parts of Semen Raphanis, 20 parts in Herba Ephedrae.
The preparation technology of this enforcement is: choose the measured crude drug of above-mentioned matter, the water content in the crude drug is lower than 10%, and by weight percentage the crude drug of choosing is weighed up, and is standby.Then the crude drug that weighs up is mixed and puts into pulverizer and pulverize, be ground into can be all coarse powder by 110 mesh sieves; And with the mixer mixing, again the medicine that mixes is carried out drying; With dried drug packages, airtight preservation pack.
Embodiment 3
A kind of medicinal and edible Chinese medicine compositions for the treatment of respiratory tract infection of pigs, its medical material is formed and percentage by weight is: 115 parts of Herba Houttuyniae, 55 parts of Folium Pyrrosiaes, 55 parts of Fructus Perillaes, 135 parts of Gypsum Fibrosum, 55 parts of Semen Sinapis Albaes, 30 parts in Radix Glycyrrhizae, 55 parts of Radix Asteriss, 55 parts of the Radixs Stemonae, 55 parts of Radix Platycodoniss, 115 parts of Semen Raphanis, 30 parts in Herba Ephedrae.
The preparation technology of this enforcement is: choose the measured crude drug of above-mentioned matter, the water content in the crude drug is lower than 10%, and by weight percentage the crude drug of choosing is weighed up, and is standby.Then the crude drug that weighs up is mixed and puts into pulverizer and pulverize, be ground into can be all coarse powder by 115 mesh sieves; And with the mixer mixing, again the medicine that mixes is carried out drying; With dried drug packages, airtight preservation pack.
Embodiment 4
A kind of medicinal and edible Chinese medicine compositions for the treatment of respiratory tract infection of pigs, its medical material is formed and percentage by weight is: 120 parts of Herba Houttuyniae, 60 parts of Folium Pyrrosiaes, 60 parts of Fructus Perillaes, 140 parts of Gypsum Fibrosum, 60 parts of Semen Sinapis Albaes, 35 parts in Radix Glycyrrhizae, 60 parts of Radix Asteriss, 60 parts of the Radixs Stemonae, 60 parts of Radix Platycodoniss, 120 parts of Semen Raphanis, 35 parts in Herba Ephedrae.
The preparation technology of this enforcement is: choose the measured crude drug of above-mentioned matter, the water content in the crude drug is lower than 10%, and by weight percentage the crude drug of choosing is weighed up, and is standby.Then the crude drug that weighs up is mixed and puts into pulverizer and pulverize, be ground into can be all coarse powder by 120 mesh sieves; And with the mixer mixing, again the medicine that mixes is carried out drying; With dried drug packages, airtight preservation pack.
Embodiment 5
A kind of medicinal and edible Chinese medicine compositions for the treatment of respiratory tract infection of pigs, its medical material is formed and percentage by weight is: 105 parts of Herba Houttuyniae, 45 parts of Folium Pyrrosiaes, 45 parts of Fructus Perillaes, 125 parts of Gypsum Fibrosum, 45 parts of Semen Sinapis Albaes, 25 parts in Radix Glycyrrhizae, 45 parts of Radix Asteriss, 45 parts of the Radixs Stemonae, 45 parts of Radix Platycodoniss, 105 parts of Semen Raphanis, 25 parts in Herba Ephedrae.
The preparation technology of this enforcement is: choose the measured crude drug of above-mentioned matter, the water content in the crude drug is lower than 10%, and by weight percentage the crude drug of choosing is weighed up, and is standby.Then the crude drug that weighs up is mixed and puts into pulverizer and pulverize, be ground into can be all coarse powder by 105 mesh sieves; And with the mixer mixing, again the medicine that mixes is carried out drying; With dried drug packages, airtight preservation pack.
Embodiment 6
A kind of medicinal and edible Chinese medicine compositions for the treatment of respiratory tract infection of pigs, its medical material is formed and percentage by weight is: 110 parts of Herba Houttuyniae, 50 parts of Folium Pyrrosiaes, 45 parts of Fructus Perillaes, 130 parts of Gypsum Fibrosum, 45 parts of Semen Sinapis Albaes, 30 parts in Radix Glycyrrhizae, 45 parts of Radix Asteriss, 45 parts of the Radixs Stemonae, 50 parts of Radix Platycodoniss, 110 parts of Semen Raphanis, 30 parts in Herba Ephedrae.
The preparation technology of this enforcement is: choose the measured crude drug of above-mentioned matter, the water content in the crude drug is lower than 10%, and by weight percentage the crude drug of choosing is weighed up, and is standby.Then the crude drug that weighs up is mixed and puts into pulverizer and pulverize, be ground into can be all coarse powder by 110 mesh sieves; And with the mixer mixing, again the medicine that mixes is carried out drying; With dried drug packages, airtight preservation pack.
Usage and dosage of the present invention: when giving the pig medicine feed, feed by the 1.5-2% spice of forage volume, be used in conjunction 2-4 days, 2 times on the one.
Below further set forth the beneficial effect of medicine of the present invention by testing example, these are tested examples and comprise that clinical observation on the therapeutic effect of the present invention tests and pharmacodynamics test.
The clinical efficacy test of (test example 1) medicine of the present invention
The clinical efficacy standard: fully recovering, asthma symptom disappears in three days, breathes clinical symptoms such as normal, feed intake and recovers normal; Clinical symptom disappearance in effective three days, the breathing character is normal, and it is relatively poor that appetite is recovered; Clinical symptoms does not disappear in invalid three days, and appetite is poor, and the state of an illness is also in constantly development, variation even dead.
Clinical treatment method: mix in pig feed with powdered composition of the present invention and to give the pig feeding, feed by the 1.5-2% spice of forage volume, be used in conjunction 2-4 days, 2 times on the one.
By in recent years in the part in villages such as Yao Duo village, Heng Duo town, Taixing City, Jiangsu Province, seven surname villages, Tang Wan village, Qian Dang village, Heng Bei village, Guan Duo village is raised pigs the family nearly 1000 examples use medicine of the present invention to treat and observation of curative effect, wherein select 5 model cases, the results are shown in Table 1
Animal toleration and the toxic reaction test of (test example 2) medicine of the present invention
Test method: get 10 of white mice, about body weight 20g, male and female half and half, irritate stomach, dosage: 0.15g/kg with drug dilution liquid of the present invention every day; Get 10 of rat, about body weight 40g, male and female half and half, irritate stomach, dosage: 0.6g/kg with drug dilution liquid of the present invention every day.
The pharmacodynamics test standard: do not see clinical symptoms such as poisoning, death after the normal perfusion, every indexs such as the mental status, feed intake are normal; After the unusual perfusion vomiting, diarrhoea arranged, do not eat, unusual clinical symptoms such as spirit is depressed, excitement; Just "+" commonly used expression, unusual with "-" expression, the results are shown in Table 2
Result of the test shows: 1, medicine of the present invention has very definite and significant curative effect to the pig asthma and cough, is total to test of cure 5 examples, cure rate 99%; 2, the test of the animal toleration of medicine and toxic reaction shows: continuous use 6 days.The result has only 2 white mice (No. 1 with No. 7), and spiritual depressed symptom appears in 0.5h after medication, but after about 15min again recovering, all the other do not see toxic reaction and death, but see the phenomenon that dispensing back feed intake increases to some extent.
6, conclusion
The medicinal and edible Chinese medicine compositions for the treatment of swine enzootic pneumonia of the present invention; confirm through a large amount of clinical efficacy tests; aspect the treatment pig asthma and cough specially good effect is being arranged, be particularly useful for the antibiotic therapy DeGrain case and easy saving of labor, safety material benefit, short treating period, curative effect height, protective rate height, be difficult for recurring, having no side effect.
Claims (2)
1. Chinese medicine composition for the treatment of the medicine-food two-purpose of respiratory tract infection of pigs, it is characterized in that: the component of said composition and each composition weight umber are: Herba Houttuyniae 100-120 part, Folium Pyrrosiae 40-60 part, Fructus Perillae 40-60 part, Gypsum Fibrosum 120-140 part, Semen Sinapis Albae 40-60 part, Radix Glycyrrhizae 15-35 part, Radix Asteris 40-60 part, Radix Stemonae 40-60 part, Radix Platycodonis 40-60 part, Semen Raphani 100-120 part, Herba Ephedrae 15-35 part.
2. the preparation method of the Chinese medicine composition of a medicine-food two-purpose for the treatment of respiratory tract infection of pigs may further comprise the steps:
(1) choose the measured crude drug of matter by the described component of claim 1, the water content in the crude drug is lower than 10%, and by weight the crude drug of choosing is weighed up, and is standby;
(2) crude drug that weighs up is mixed;
(3) batch mixing that mixes is put into pulverizer and pulverizes, be ground into can be all coarse powder by the 100-120 mesh sieve;
(4) mix with mixer, the medicine that mixes is carried out drying;
(5) with dried drug packages, airtight preservation.
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| CN104138454A (en) * | 2014-07-19 | 2014-11-12 | 扬中牧乐药业有限公司 | Veterinary cough guard oral solution and preparation method thereof |
| CN105168993A (en) * | 2015-08-06 | 2015-12-23 | 钱峰 | Medicinal and edible Chinese herbal composition for treating chicken respiratory infections and its preparation method |
| CN105168994A (en) * | 2015-08-06 | 2015-12-23 | 钱峰 | Medicinal and edible Chinese herbal composition for treating chicken respiratory infections |
| CN106620266A (en) * | 2016-12-05 | 2017-05-10 | 张明 | Traditional Chinese medicine composition for treating mycoplasmal pneumonia of swine |
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Application publication date: 20120808 Assignee: Xuzhou Jinpai Pharmaceutical Co., Ltd. Assignor: Qian Feng Contract record no.: 2015320000164 Denomination of invention: Traditional Chinese medicinal composition used as both food and medicine for treating porcine respiratory tract infection, and preparation method thereof Granted publication date: 20130807 License type: Exclusive License Record date: 20150413 |
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