CN1692794A - Fish growth promoting prepn. made up of Chinese herb medicines - Google Patents
Fish growth promoting prepn. made up of Chinese herb medicines Download PDFInfo
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- CN1692794A CN1692794A CNA2004100240887A CN200410024088A CN1692794A CN 1692794 A CN1692794 A CN 1692794A CN A2004100240887 A CNA2004100240887 A CN A2004100240887A CN 200410024088 A CN200410024088 A CN 200410024088A CN 1692794 A CN1692794 A CN 1692794A
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- 239000003814 drug Substances 0.000 title claims description 29
- 229940079593 drugs Drugs 0.000 title description 15
- 230000001737 promoting Effects 0.000 title description 3
- 241000251468 Actinopterygii Species 0.000 claims abstract description 43
- 235000008599 Poria cocos Nutrition 0.000 claims abstract description 11
- 239000000843 powder Substances 0.000 claims abstract description 7
- 238000002360 preparation method Methods 0.000 claims description 16
- 241000411851 herbal medicine Species 0.000 claims description 12
- 241000132012 Atractylodes Species 0.000 claims description 10
- 235000016855 Biancospino Nutrition 0.000 claims description 10
- 241000756943 Codonopsis Species 0.000 claims description 10
- 241001092040 Crataegus Species 0.000 claims description 10
- 235000017181 Crataegus chrysocarpa Nutrition 0.000 claims description 10
- 235000004423 Crataegus monogyna Nutrition 0.000 claims description 10
- 239000009636 Huang Qi Substances 0.000 claims description 10
- 244000197580 Poria cocos Species 0.000 claims description 10
- 240000004980 Rheum officinale Species 0.000 claims description 10
- 235000008081 Rheum officinale Nutrition 0.000 claims description 10
- 241000207929 Scutellaria Species 0.000 claims description 10
- 239000010231 banlangen Substances 0.000 claims description 10
- 235000002313 hawthorn Nutrition 0.000 claims description 10
- 235000009444 hawthorn Nutrition 0.000 claims description 10
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- 235000009685 hawthorn Nutrition 0.000 claims description 10
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- 235000013214 hawthorn Nutrition 0.000 claims description 10
- 235000013246 hawthorn Nutrition 0.000 claims description 10
- 235000017423 hawthorn Nutrition 0.000 claims description 10
- 239000000796 flavoring agent Substances 0.000 claims description 6
- 235000019634 flavors Nutrition 0.000 claims description 6
- 238000002156 mixing Methods 0.000 claims description 4
- 239000000463 material Substances 0.000 abstract description 4
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- 229940107666 ASTRAGALUS ROOT Drugs 0.000 abstract 1
- 240000001754 Peltandra virginica Species 0.000 abstract 1
- 235000001188 Peltandra virginica Nutrition 0.000 abstract 1
- 241000270666 Testudines Species 0.000 abstract 1
- 201000010099 disease Diseases 0.000 description 18
- 241001482311 Trionychidae Species 0.000 description 16
- 230000000694 effects Effects 0.000 description 12
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- 235000019789 appetite Nutrition 0.000 description 5
- 230000002265 prevention Effects 0.000 description 5
- 241000196324 Embryophyta Species 0.000 description 4
- 210000002784 Stomach Anatomy 0.000 description 4
- 210000000538 Tail Anatomy 0.000 description 4
- 230000036039 immunity Effects 0.000 description 4
- XEEYBQQBJWHFJM-UHFFFAOYSA-N iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 4
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- 239000007789 gas Substances 0.000 description 1
- 230000001900 immune effect Effects 0.000 description 1
- 230000004301 light adaptation Effects 0.000 description 1
- 239000002075 main ingredient Substances 0.000 description 1
- 235000013372 meat Nutrition 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- MYMOFIZGZYHOMD-UHFFFAOYSA-N oxygen Chemical compound O=O MYMOFIZGZYHOMD-UHFFFAOYSA-N 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 238000006213 oxygenation reaction Methods 0.000 description 1
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- 230000000144 pharmacologic effect Effects 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
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- 238000007789 sealing Methods 0.000 description 1
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Classifications
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
- Y02A40/80—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in fisheries management
- Y02A40/81—Aquaculture, e.g. of fish
- Y02A40/818—Alternative feeds for fish, e.g. in aquacultures
Abstract
A Chinese-medicinal powder added in bait for fish, turtle, shrimp, etc, especially for eel, is prepared from 12 Chinese-medicinal materials including astragalus root, pilose asiabell root, tuckahoe, Chinese angelica root, etc.
Description
Affiliated technical field the present invention relates to a kind of Chinese herbal and crude drugs preparations, particularly a kind of Chinese herbal medicine powder of the fish use stage of fattening.
Background technology in recent years, development along with culture fishery, popularizing of intensive culture mode, though the research of aquatic products disease and aquatic products disease prevention and cure technology have obtained very big development and raising, but fish disease and epidemic situation are not controlled completely and are eliminated, and have occurred many new fish diseases on the contrary again.Particularly in recent years, the Europe eel is in a large amount of breed in Fujian, and reasons such as frequently-occurring disease and poor growth have had a strong impact on the economic benefit of eel field.On the other hand, because the abuse of Western medicine makes many fish disease pathogenic bacteria produce the resistance to the action of a drug, caused new difficulty to clinical treatment.In addition, Western medicine residual in aquatic products meat, also the health of human body in serious harm.The resources of medicinal plant of China is abundant, adopts the with a long history of herbal control people, animal disease, uses in the stage of fattening that research adopts Chinese herbal medicine to prevent and treat fish disease and fish as fish feed additive in recent years, obtains certain effect.
" Laiyang Agricultural College journal " the 4th phase in 2000 has been delivered the article " Chinese herbal feed additive improves the experimental study of the production performance of soft-shelled turtle " of Wu Defeng etc., introduced with the disease-resistant weightening finish additive of Chinese prescription as soft-shelled turtle, this Chinese prescription is the Radix Astragali, Radix Codonopsis, the bighead atractylodes rhizome, Poria cocos, Radix Angelicae Sinensis, Divine Comedy, hawthorn, radix scrophulariae, rheum officinale, the root of large-flowered skullcap, Radix Isatidis and Radix Glycyrrhizae.All medicines close the solarization dry grinding, cross 50 mesh sieves, and add in the daily ration with 2%, 3% ratio respectively.
" Fujian Agricultural Univeristy's journal " the 1st phase of calendar year 2001 has been delivered the article " Chinese herbal feed additive is to the influence of Europe eel culture efficiency " of Wu Defeng etc., introduced with the disease-resistant weightening finish additive of Chinese prescription as the Europe eel, this Chinese prescription is the Radix Astragali, Radix Codonopsis, the bighead atractylodes rhizome, Poria cocos, Radix Angelicae Sinensis, Divine Comedy, hawthorn, radix scrophulariae, rheum officinale, the root of large-flowered skullcap, Radix Isatidis and Radix Glycyrrhizae.All medicines close the solarization dry grinding, cross 50 mesh sieves, add in the bait with 2% ratio.
Summary of the invention the objective of the invention is to develop a kind of body resistivity, multiple acute and chronic infectious disease of prevention that can strengthen fish, can promote the Chinese herbal and crude drugs preparations that sashimi (raw fish) is long again.
The fertile fish preparation of a kind of Chinese herbal medicine of the present invention is a kind of Chinese herbal medicine powder, is flaxen powder, the little perfume (or spice) of gas, sweet and slightly bitter taste.The present invention selects the Radix Astragali, Radix Codonopsis, the bighead atractylodes rhizome, Poria cocos, Radix Angelicae Sinensis, Divine Comedy, hawthorn, radix scrophulariae, rheum officinale, the root of large-flowered skullcap, Radix Isatidis, Radix Glycyrrhizae to make up, and the shared percentage of each medicine of distinguishing the flavor of is as follows:
Radix Astragali 12%-15% Radix Codonopsis 10%-12% bighead atractylodes rhizome 8%-10% Poria cocos 5%-8%
Radix Angelicae Sinensis 10%-12% Divine Comedy 6%-8% hawthorn 6%-8% radix scrophulariae 6%-8%
Rheum officinale 6%-8% root of large-flowered skullcap 6%-8% Radix Isatidis 6%-8% Radix Glycyrrhizae 4%-6%
The preparation method of the fertile fish preparation of a kind of Chinese herbal medicine of the present invention with above 12 flavor medicine oven dry, chopping, was ground into the powder of 50 mesh sieves, and by described percentage mixing.
The fertile fish preparation of a kind of Chinese herbal medicine of the present invention adopts the Radix Astragali, Radix Codonopsis tonifying middle-Jiao and Qi, solid table to break even and be main ingredient, and the bighead atractylodes rhizome, Poria cocos tonifying spleen are good for the stomach, the taste function of conditioning fish; Chinese Angelica blood replonishing is invigorated blood circulation, separate stiff vigorous blood circulation, Divine Comedy, hawthorn promotion appetite, help digestion and stomach, the cool blood of radix scrophulariae, rheum officinale, the root of large-flowered skullcap, clearing heat and detoxicating, the antibiotic diseases prevention of Radix Isatidis, strengthen function of immune system, Radix Glycyrrhizae reason lung and in, all medicines in full side complement each other, play altogether invigorate the spleen and benefit qi, promoting digestion, clearing heat and detoxicating merit, so vigorous taste of energy and blood circulation function promote to digest and assimilate, and reach the weightening finish purpose of fattening.
At the physilogical characteristics of fish and clinical disease performance, with tonifying spleen be good for the stomach, promoting digestion, cooling and activating blood be the rules of treatment and prescription, not only can promote growth, weightening finish obviously, and can strengthen the body resistivity, prevents multiple acute and chronic infectious disease.For three class seedlings in the eel (being commonly called as iron nail eel, stiff eel and old man eel), diagnosis and treatment based on an overall analysis of the illness and the patient's condition according to tcm theory, think that the formation of three class seedlings is that dysfunction of the spleen, stomach are received deficiency, the blood clotting stagnation of the circulation of vital energy causes that qi and blood twoly loses, yin-yang all loss, according to the tcm theory of " the spleen being the foundation of acquired constitution " and " excessive disease located in Yangming; deficient disease located in Taiyin ",, suitably nurse one's health based on the strong fortune of tonifying spleen, vigorous blood follows, promotes appetite, reaches the purpose of separating stiff weightening finish.Prescription cooperates rigorous, does not have the incompatibility of eighteen incompatibilities, nineteen counteraction, experimental results show that to be the safety non-toxic preparation, is specially adapted to the eel weightening finish of fattening of (comprising Europe eel, Japanese eel, Chinese local eel), promotes growth.
Use the drug cost of Chinese herbal and crude drugs preparations low, nontoxic, nuisanceless, have no side effect, prevent and treat disease and immunologic function is strong, can not develop immunity to drugs, the gaining effect of fish is obvious.The said herbal medicine preparation makes an addition in the bait of eel, the eel skin Lightening of medication group, and glossiness and brightness all are better than control group, and protein, dry, ash content and amino acid content are also than the control group height.For weak and sickly or be in the plant in epidemic-stricken area, and stop empty, poor, the poky eel of appetite after being ill, the diseases prevention gaining effect is more obvious.The function that growth promotion, enhancing immunity are arranged too for soft-shelled turtle, shrimp and other fish in addition.
The specific embodiment is following further sets forth fertile fish preparation of a kind of Chinese herbal medicine of the present invention and result of use thereof by testing example.
Embodiment: the fertile fish preparation----" natural fertile fish health " of a kind of Chinese herbal medicine
" natural fertile fish health " is made up of the Radix Astragali, Radix Codonopsis, the bighead atractylodes rhizome, Poria cocos, Radix Angelicae Sinensis, Divine Comedy, hawthorn, radix scrophulariae, rheum officinale, the root of large-flowered skullcap, Radix Isatidis, Radix Glycyrrhizae, and the shared percentage of each medicine of distinguishing the flavor of is as follows:
The Radix Astragali 15% Radix Codonopsis 11% bighead atractylodes rhizome 9% Poria cocos 7%
Radix Angelicae Sinensis 11% Divine Comedy 7% hawthorn 7% radix scrophulariae 7%
Rheum officinale 7% root of large-flowered skullcap 7% Radix Isatidis 7% Radix Glycyrrhizae 5%
The preparation method of " natural fertile fish health " with above 12 flavor medicines oven dry, chopping, was ground into the powder of 50 mesh sieves, and by described weight mixing, was distributed into bag by 500 gram/bags or 250 gram/bags then, and lucifuge, sealing, kept dry are standby.
Function: blood yiqi, invigorating the spleen protect the liver, clearing heat and detoxicating, the weightening finish of fattening, strengthen immunity.
Cure mainly: poor, the weak and sickly and poor growth of the appetite of soft-shelled turtle, eel and multiple fish.
Usage and consumption: add according to 2% of bait dry weight, feed after mixing thoroughly.
Below be the safety test of " natural fertile fish health " and the clinical trial result of Europe eel and soft-shelled turtle.
One, the safety (toxicity) of " natural fertile fish health " Chinese herbal and crude drugs preparations test
1,1. experimental animal of test material: healthy Europe eel 750 tails
2. trial drug: " natural fertile fish health "
2, test method
Healthy Europe eel 750 tails are divided into five groups, every group of each 150 tail are raised respectively in five aquariums, and the water temperature of aquarium is controlled at 25 ℃, make an addition in the feed by the various dose of " natural fertile fish health ", addition is 2%, 3%, 5%, 10% and control group 0%.Through 20 days feeding experiments, examine feed intake, the state of mind, active situation and death or the incidence of Europe eel.
3, result of the test (seeing table 1 for details)
4, conclusion: result of the test shows that during medication, control group is compared with test group, and the feed intake and the state of mind do not have too big variation, and body condition is normal, and 2% group of the addition of test group is the same with 3% group of effect.But consumption is unsuitable excessive, and consumption is 5% and 10% o'clock, when just beginning feed intake and the state of mind have influenced, but just adaptation gradually after 10 days.Illustrate that this preparation is fit to eel and takes, and safe, nontoxic.
The safety test result of table 1 " natural fertile fish health "
Annotate: the state of mind of "+" expression Europe eel in the table, "+" multilist more shows that the state of mind is good more, the grazing rate computational methods are the percentage of Europe eel daily ingestion amount and Europe eel body weight.
Two, Europe eel clinical application effect:
1, clinical testing
(1) 1. experimental animal of test material: choose about 180 ages in days, every tail average weight 100 grams, Europe eel 800 tails under normal raising condition.2. trial drug: " natural fertile fish health ".
(2) test method
To be divided into four groups at Europe eel 800 tails under the normal raising condition, every group 200 tail raised respectively in four aquariums, and the water temperature of aquarium is controlled at 20-25 ℃, make an addition in the feed by " natural fertile fish health " various dose, addition be respectively 2%, 3%, 5% and control group 0%.Through 90 days clinical feeding experiments, examine grazing rate, body condition, weightening finish and the death state of Europe eel.
(3) result of the test (seeing table 2 for details)
Table 2 " natural fertile fish health " is to the clinical trial result of Europe eel
Annotate: the dosage that 1 group of Europe eel of test is added " Fei Yukang " in the table is 2%, and the dosage of testing 2 groups of Europe eels interpolations is 3%, and the dosage of testing 3 groups of Europe eels interpolations is 5%, and control group Europe eel is not added.Before on-test, 4 groups Europe eel body weight is similar, average about 100 grams, and raising condition (comprising feed, water temperature, oxygenation) test group is the same with control group.
From clinical test results as can be seen, the Europe eel is had good gaining effect, in 90 days of experimental period, test group is compared with control group, and every tail fish weightening finish difference is 22.54 ± 8.57 (p＜0.05), and difference is very remarkable.Also can find out from result of the test, 3 kinds of additions of test group all have effect of gain in various degree, but the result differs little from weightening finish, and add 5% test group effect on the contrary not as 2% and 3% test group, and from economic benefit, the test group benefit of interpolation 2% is best, thinks that thus the optimum addition of " natural fertile fish health " should be 2%.
2, clinical expanding test
Result according to clinical testing and pharmacological testing, with " natural fertile fish health " successively in Xiapu, plants such as Putian, Longhai City, Foochow, Yongtai amount to 300,000 tail Europe eels and carry out expanding test, these plants reflect that generally the growth promotion weightening finish to the Europe eel has good effect, not only can promote appetite, weightening finish is fattened, can also strengthen immunity of organisms, multiple disease all there is the excellent prevention effect, particularly support three little class seedlings for those, be commonly called as iron nail eel, stiff eel and old man eel, the growth promotion gaining effect is more remarkable.
Three, the clinical application effect of soft-shelled turtle:
1, clinical testing
(1) 1. experimental animal of test material: choose 6000 of soft-shelled turtles on average only weighing 900 grams, put in a suitable place to breed in 180 square metres soft-shelled turtle pond,, be numbered A, B, C, D, E respectively for examination soft-shelled turtle Chi5Kou.1200 of soft-shelled turtles are being supported in every mouthful of soft-shelled turtle pond approximately.2. trial drug: " natural fertile fish health ".
(2) test method
Test is carried out at production turtle-breeding field, control group and test group are except that medication is different, each project and raising term harmonizations such as the survey of water quality mirror, dissolved oxygen mensuration, pH value, duration of test, test group equates substantially with control group feed consumption, " the natural fertile fish health " in A, B pond pressed 2% interpolation of feed, and " the natural fertile fish health " in C, D pond pressed 3% of feed and added not medication of control group.
(3) result of the test
Deliver weighing results for sale after 90 days and show, used the soft-shelled turtle comparison of " natural fertile fish health " obvious according to the soft-shelled turtle weightening finish in pond.(seeing table 3 for details)
Table 3 " natural fertile fish health " is to the clinical trial result of soft-shelled turtle
| The medicine addition | Pond number | Throwing seedling number (only/pond) | Soft-shelled turtle is on average heavy before the medication | Medication was treated back 90 days | |
| Soft-shelled turtle survival number (only) | Average heavy (gram) | ||||
| 2％ | ?A | ??1204 | ??243±14.67 | ????1102 | ??525±5.08 |
| 2％ | ?B | ??1252 | ??240±6.42 | ????1128 | ??528±7.45 |
| 3％ | ?C | ??1153 | ??238±5.92 | ????1090 | ??534±5.72 |
| 3％ | ?D | ??1222 | ??241±5056 | ????1152 | ??538±6.51 |
| Control group | ?E | ??1182 | ??245±20.81 | ????860 | ??501±6.69 |
With the A, the B that cross " natural fertile fish health ", C, D pond deliver body weight and E pond for sale relatively, handle by biometrics, test data is through variance analysis, the duncan's new multiple range method multiple ratio more as can be seen: it is not remarkable respectively to organize difference before 1. testing, P＞0.05; 2. compare in test back A, B, C, D pond and E pond, and difference is all extremely remarkable, P＜0.01.
Claims (2)
1, the fertile fish preparation of a kind of Chinese herbal medicine, make up by the Radix Astragali, Radix Codonopsis, the bighead atractylodes rhizome, Poria cocos, Radix Angelicae Sinensis, Divine Comedy, hawthorn, radix scrophulariae, rheum officinale, the root of large-flowered skullcap, Radix Isatidis, Radix Glycyrrhizae, and dry, shred, be ground into powder, mixing then, the shared percentage of medicine that it is characterized in that respectively distinguishing the flavor of is as follows:
Radix Astragali 12%-15% Radix Codonopsis 10%-12% bighead atractylodes rhizome 8%-10% Poria cocos 5%-8%
Radix Angelicae Sinensis 10%-12% Divine Comedy 6%-8% hawthorn 6%-8% radix scrophulariae 6%-8%
Rheum officinale 6%-8% root of large-flowered skullcap 6%-8% Radix Isatidis 6%-8% Radix Glycyrrhizae 4%-6%
2, according to the fertile fish preparation of the described a kind of Chinese herbal medicine of claim, the shared percentage of medicine that it is characterized in that respectively distinguishing the flavor of is as follows:
The Radix Astragali 15% Radix Codonopsis 11% bighead atractylodes rhizome 9% Poria cocos 7%
Radix Angelicae Sinensis 11% Divine Comedy 7% hawthorn 7% radix scrophulariae 7%
Rheum officinale 7% root of large-flowered skullcap 7% Radix Isatidis 7% Radix Glycyrrhizae 5%
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| CNB2004100240887A CN1295982C (en) | 2004-05-09 | 2004-05-09 | Fish growth promoting prepn. made up of Chinese herb medicines |
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| CNB2004100240887A CN1295982C (en) | 2004-05-09 | 2004-05-09 | Fish growth promoting prepn. made up of Chinese herb medicines |
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| CN1692794A true CN1692794A (en) | 2005-11-09 |
| CN1295982C CN1295982C (en) | 2007-01-24 |
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| CN101961064A (en) * | 2010-09-28 | 2011-02-02 | 山东大学威海分校 | Preparation method and use of compound traditional Chinese medicinal preparation |
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| CN105010861A (en) * | 2015-07-20 | 2015-11-04 | 句容市郭庄镇南河农庄 | High immunity trionyx sinensis Chinese herbal medicine feed additive and preparation method and application thereof |
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Assignee: Fujian Zhengyuan Feed Co., Ltd. Assignor: Fujian Agricultural and Forestry University Contract fulfillment period: 2008.8.13 to 2013.9.12 contract change Contract record no.: 2008350000029 Denomination of invention: Fish growth promoting prepn. made up of Chinese herb medicines Granted publication date: 20070124 License type: Exclusive license Record date: 2008.9.18 |
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