Summary of the invention
Technical problem to be solved by this invention is to provide a kind of fishing Chinese medicine composition with antibacterial and anti-inflammation functions.
Another technical problem to be solved by this invention is to provide the above-mentioned preparation method of the fishing of antibacterial and anti-inflammation functions with Chinese medicine composition that have.
For solving the problems of the technologies described above, technical scheme of the present invention is:
A kind of fishing Chinese medicine composition with antibacterial and anti-inflammation functions, mainly by the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Radix Et Rhizoma Rhei, Cortex Magnoliae Officinalis, Radix Isatidis and Radix Glycyrrhizae, formed, by its parts by weight, count Radix Astragali 8.1-18.1 part, Rhizoma Atractylodis Macrocephalae 15-25 part, Radix Et Rhizoma Rhei 8.5-18.5 part, Cortex Magnoliae Officinalis 1.5-11.5 part, Radix Isatidis 28.5-38.5 part, Radix Glycyrrhizae 8.3-18.3 part.
Preferably, the above-mentioned fishing Chinese medicine composition with antibacterial and anti-inflammation functions, by its parts by weight Radix Astragali 11-17 part, Rhizoma Atractylodis Macrocephalae 18-23 part, Radix Et Rhizoma Rhei 10-17 part, Cortex Magnoliae Officinalis 3-9 part, Radix Isatidis 30-37 part, Radix Glycyrrhizae 10-16 part.
Preferably, the above-mentioned fishing Chinese medicine composition with antibacterial and anti-inflammation functions, by 14 parts of its parts by weight Radixs Astragali, 20 parts of the Rhizoma Atractylodis Macrocephalaes, 14 parts of Radix Et Rhizoma Rhei, 7 parts of Cortex Magnoliae Officinalis, 33 parts of Radix Isatidis, 14 parts, Radix Glycyrrhizae.
Preferably, the above-mentioned fishing Chinese medicine composition with antibacterial and anti-inflammation functions, also comprise phagostimulant, by its parts by weight, count Radix Astragali 8.1-18.1 part, Rhizoma Atractylodis Macrocephalae 15-25 part, Radix Et Rhizoma Rhei 8.5-18.5 part, Cortex Magnoliae Officinalis 1.5-11.5 part, Radix Isatidis 28.5-38.5 part, Radix Glycyrrhizae 8.3-18.3 part, phagostimulant 1-2 part.
Preferably, the above-mentioned fishing Chinese medicine composition with antibacterial and anti-inflammation functions, described phagostimulant is allicin powder or betanin.
Preferably, the above-mentioned fishing Chinese medicine composition with antibacterial and anti-inflammation functions, count 14 parts of the Radixs Astragali, 21 parts of the Rhizoma Atractylodis Macrocephalaes, 14 parts of Radix Et Rhizoma Rhei, 7.5 parts of Cortex Magnoliae Officinalis, 35 parts of Radix Isatidis, 15 parts, Radix Glycyrrhizae, 1.5 parts of betanins by its parts by weight.
The above-mentioned fishing with antibacterial and anti-inflammation functions preparation method of Chinese medicine composition, concrete preparation process is as follows:
(1) taking by weight Radix Astragali 8.1-18.1 part, Rhizoma Atractylodis Macrocephalae 15-25 part, Radix Et Rhizoma Rhei 8.5-18.5 part, Cortex Magnoliae Officinalis 1.5-11.5 part, Radix Isatidis 28.5-38.5 part, Radix Glycyrrhizae 8.3-18.3 part is raw material;
(2) each flavor Chinese medicine is cleaned, dried, micronizing is to 30-60 μ m, and mix homogeneously, obtain.
Preferably, the above-mentioned fishing with antibacterial and anti-inflammation functions preparation method of Chinese medicine composition, concrete preparation process is as follows:
(1) taking by weight Radix Astragali 8.1-18.1 part, Rhizoma Atractylodis Macrocephalae 15-25 part, Radix Et Rhizoma Rhei 8.5-18.5 part, Cortex Magnoliae Officinalis 1.5-11.5 part, Radix Isatidis 28.5-38.5 part, Radix Glycyrrhizae 8.3-18.3 part, phagostimulant 1-2 part is raw material;
(2) each flavor Chinese medicine is cleaned, dried, micronizing is to 30-60 μ m, and mix homogeneously, obtain.
Preferably, the above-mentioned fishing with antibacterial and anti-inflammation functions preparation method of Chinese medicine composition, micronizing to 44 μ m in described step (2).
The above-mentioned fishing with antibacterial and anti-inflammation functions freely eats for according to the ratio of 1g/kg feedstuff, described Chinese medicine composition being added in normal feedstuff with the consumption of Chinese medicine composition, and every day 2-3 time, being used in conjunction 3-5 days is a course for the treatment of.
The invention has the beneficial effects as follows:
The above-mentioned fishing Chinese medicine composition with antibacterial and anti-inflammation functions, by the Chinese medicine reasonable formula, effect with heat-clearing and toxic substances removing, anti-inflammation, not only can effectively improve the resistance against diseases of fish and shrimp individuality, inflammation-inhibiting occurs, and can greatly strengthen the fish and shrimp immunologic function simultaneously, and prescription is nontoxic, warm in nature and, can in the fish and shrimp body, not produce residually, not produce drug resistance, can effectively be degraded by body; Its preparation method is simple, and cost is low, is applicable to the needs that large-scale industrial is produced.
The specific embodiment
Below in conjunction with specific embodiment, technical scheme of the present invention is further described.
Embodiment 1
A kind of fishing Chinese medicine composition with antibacterial and anti-inflammation functions, be comprised of the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Radix Et Rhizoma Rhei, Cortex Magnoliae Officinalis, Radix Isatidis and Radix Glycyrrhizae, and its weight is Radix Astragali 14kg, Rhizoma Atractylodis Macrocephalae 20kg, Radix Et Rhizoma Rhei 14kg, Cortex Magnoliae Officinalis 7kg, Radix Isatidis 33kg, Radix Glycyrrhizae 14kg.
The above-mentioned fishing with antibacterial and anti-inflammation functions preparation method of Chinese medicine composition, concrete preparation process is as follows:
(1) take Radix Astragali 14kg, Rhizoma Atractylodis Macrocephalae 20kg, Radix Et Rhizoma Rhei 14kg, Cortex Magnoliae Officinalis 7kg, Radix Isatidis 33kg, Radix Glycyrrhizae 14kg are raw material;
(2) each flavor Chinese medicine is cleaned, dried, micronizing, smashing fineness is 44 μ m, mix homogeneously, obtain.
Embodiment 2
A kind of fishing Chinese medicine composition with antibacterial and anti-inflammation functions, be comprised of the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Radix Et Rhizoma Rhei, Cortex Magnoliae Officinalis, Radix Isatidis and Radix Glycyrrhizae, and its weight is Radix Astragali 18.1kg, Rhizoma Atractylodis Macrocephalae 25kg, Radix Et Rhizoma Rhei 8.5kg, Cortex Magnoliae Officinalis 1.5kg, Radix Isatidis 28.5kg, Radix Glycyrrhizae 18.3kg.
The above-mentioned fishing with antibacterial and anti-inflammation functions preparation method of Chinese medicine composition, concrete preparation process is as follows:
(1) take Radix Astragali 18.1kg, Rhizoma Atractylodis Macrocephalae 25kg, Radix Et Rhizoma Rhei 8.5kg, Cortex Magnoliae Officinalis 1.5kg, Radix Isatidis 28.5kg, Radix Glycyrrhizae 18.3kg are raw material;
(2) each flavor Chinese medicine is cleaned, dried, micronizing, smashing fineness is 30 μ m, mix homogeneously, obtain.
Embodiment 3
A kind of fishing Chinese medicine composition with antibacterial and anti-inflammation functions, be comprised of the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Radix Et Rhizoma Rhei, Cortex Magnoliae Officinalis, Radix Isatidis and Radix Glycyrrhizae, and its weight is Radix Astragali 8.1kg, Rhizoma Atractylodis Macrocephalae 15kg, Radix Et Rhizoma Rhei 18.5kg, Cortex Magnoliae Officinalis 11.5kg, Radix Isatidis 38.5kg, Radix Glycyrrhizae 8.3kg.
The above-mentioned fishing with antibacterial and anti-inflammation functions preparation method of Chinese medicine composition, concrete preparation process is as follows:
(1) take Radix Astragali 8.1kg, Rhizoma Atractylodis Macrocephalae 15kg, Radix Et Rhizoma Rhei 18.5kg, Cortex Magnoliae Officinalis 11.5kg, Radix Isatidis 38.5kg, Radix Glycyrrhizae 8.3kg are raw material;
(2) each flavor Chinese medicine is cleaned, dried, micronizing, smashing fineness is 60 μ m, mix homogeneously, obtain.
Embodiment 4
A kind of fishing Chinese medicine composition with antibacterial and anti-inflammation functions, be comprised of the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Radix Et Rhizoma Rhei, Cortex Magnoliae Officinalis, Radix Isatidis and Radix Glycyrrhizae, and its weight is Radix Astragali 11kg, Rhizoma Atractylodis Macrocephalae 23kg, Radix Et Rhizoma Rhei 17kg, Cortex Magnoliae Officinalis 3kg, Radix Isatidis 30kg, Radix Glycyrrhizae 10kg.
The above-mentioned fishing with antibacterial and anti-inflammation functions preparation method of Chinese medicine composition, concrete preparation process is as follows:
(1) take Radix Astragali 11kg, Rhizoma Atractylodis Macrocephalae 23kg, Radix Et Rhizoma Rhei 17kg, Cortex Magnoliae Officinalis 3kg, Radix Isatidis 30kg, Radix Glycyrrhizae 10kg are raw material;
(2) each flavor Chinese medicine is cleaned, dried, micronizing, smashing fineness is 52 μ m, mix homogeneously, obtain.
Embodiment 5
A kind of fishing Chinese medicine composition with antibacterial and anti-inflammation functions, be comprised of the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Radix Et Rhizoma Rhei, Cortex Magnoliae Officinalis, Radix Isatidis and Radix Glycyrrhizae, and its weight is Radix Astragali 17kg, Rhizoma Atractylodis Macrocephalae 18kg, Radix Et Rhizoma Rhei 10kg, Cortex Magnoliae Officinalis 9kg, Radix Isatidis 37kg, Radix Glycyrrhizae 16kg.
The above-mentioned fishing with antibacterial and anti-inflammation functions preparation method of Chinese medicine composition, concrete preparation process is as follows:
(1) take Radix Astragali 17kg, Rhizoma Atractylodis Macrocephalae 18kg, Radix Et Rhizoma Rhei 10kg, Cortex Magnoliae Officinalis 9kg, Radix Isatidis 37kg, Radix Glycyrrhizae 16kg are raw material;
(2) each flavor Chinese medicine is cleaned, dried, micronizing, smashing fineness is 35 μ m, mix homogeneously, obtain.
Embodiment 6
A kind of fishing Chinese medicine composition with antibacterial and anti-inflammation functions, the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Radix Et Rhizoma Rhei, Cortex Magnoliae Officinalis, Radix Isatidis, Radix Glycyrrhizae and betanin, consist of, its weight is Radix Astragali 14kg, Rhizoma Atractylodis Macrocephalae 21kg, Radix Et Rhizoma Rhei 14kg, Cortex Magnoliae Officinalis 7.5kg, Radix Isatidis 35kg, Radix Glycyrrhizae 15kg, betanin 1.5kg.
The above-mentioned fishing with antibacterial and anti-inflammation functions preparation method of Chinese medicine composition, concrete preparation process is as follows:
(1) take Radix Astragali 14kg, Rhizoma Atractylodis Macrocephalae 21kg, Radix Et Rhizoma Rhei 14kg, Cortex Magnoliae Officinalis 7.5kg, Radix Isatidis 35kg, Radix Glycyrrhizae 15kg, betanin 1.5kg is raw material;
(2) each flavor Chinese medicine is cleaned, dried, micronizing, smashing fineness is 47 μ m, mix homogeneously, obtain.
Embodiment 7
A kind of fishing Chinese medicine composition with antibacterial and anti-inflammation functions, the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Radix Et Rhizoma Rhei, Cortex Magnoliae Officinalis, Radix Isatidis, Radix Glycyrrhizae and allicin powder, consist of, its weight is Radix Astragali 15kg, Rhizoma Atractylodis Macrocephalae 24kg, Radix Et Rhizoma Rhei 15kg, Cortex Magnoliae Officinalis 11kg, Radix Isatidis 30kg, Radix Glycyrrhizae 18kg, allicin powder 1.4kg.
The above-mentioned fishing with antibacterial and anti-inflammation functions preparation method of Chinese medicine composition, concrete preparation process is as follows:
(1) take Radix Astragali 15kg, Rhizoma Atractylodis Macrocephalae 24kg, Radix Et Rhizoma Rhei 15kg, Cortex Magnoliae Officinalis 11kg, Radix Isatidis 30kg, Radix Glycyrrhizae 18kg, allicin powder 1.4kg is raw material;
(2) each flavor Chinese medicine is cleaned, dried, micronizing, smashing fineness is 39 μ m,, mix homogeneously, obtain.
Embodiment 8
A kind of fishing Chinese medicine composition with antibacterial and anti-inflammation functions, the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Radix Et Rhizoma Rhei, Cortex Magnoliae Officinalis, Radix Isatidis, Radix Glycyrrhizae and betanin, consist of, its weight is Radix Astragali 15kg, Rhizoma Atractylodis Macrocephalae 21kg, Radix Et Rhizoma Rhei 9kg, Cortex Magnoliae Officinalis 2kg, Radix Isatidis 38kg, Radix Glycyrrhizae 9kg, betanin 1kg.
The above-mentioned fishing with antibacterial and anti-inflammation functions preparation method of Chinese medicine composition, concrete preparation process is as follows:
(1) take Radix Astragali 15kg, Rhizoma Atractylodis Macrocephalae 21kg, Radix Et Rhizoma Rhei 9kg, Cortex Magnoliae Officinalis 2kg, Radix Isatidis 38kg, Radix Glycyrrhizae 9kg, betanin 1kg is raw material;
(2) each flavor Chinese medicine is cleaned, dried, micronizing, smashing fineness is 56 μ m,, mix homogeneously, obtain.
Each amounts of components of the described Chinese crude drug of one of embodiment 1-8 is increased or reduces according to same ratio, and the parts by weight relation of each component of gained all belongs to protection scope of the present invention.
The described Chinese crude drug of embodiment 1-8 all meets " Chinese veterinary pharmacopoeia " version two ministerial standards in 2005.
The composition principle of Chinese medicine composition of the present invention is: Radix Astragali sweet in the mouth is warm in nature, is important QI invigorating Chinese medicine, has the effect of QI invigorating benefit table, detoxification granulation promoting, wherein contain the plurality of active ingredients such as polysaccharide, osajin and Saponin class, the energy anticoagulant, reduce blood viscosity and coagulability, strengthen plasmin activity, relaxing smooth muscle, expansion lung, the heart, cerebrovascular, reduce vascular resistance, improve blood circulation, especially improve microcirculation, thereby improve cardio-pulmonary function, promote pulmonary ventilation, organization aeration; The Radix Astragali can effectively reduce lipid peroxidation, reduces the generation of malonaldehyde, and the effect of stronger removing free radical is arranged, and the effective ingredient astragaloside of the Radix Astragali has the effects such as antiinflammatory, calmness, analgesia; The Radix Astragali and Cortex Magnoliae Officinalis, the Rhizoma Atractylodis Macrocephalae, Radix Isatidis four flavor Chinese medicines have the tonify deficiency righting, regulate the effect of negative and positive; The Radix Astragali and Radix Glycyrrhizae, Radix Et Rhizoma Rhei three flavor Chinese medicines have the effect of heat-clearing and toxic substances removing, anti-inflammation.Full side's Synergistic, effect with anti-inflammation, improve culturing fish and shrimp body nonspecific immunity function simultaneously, improve its Anti-bacterium ability, and dosage is little, be applicable to the control of fish and shrimp common bacteria virosis, especially adopt the described proportioning control of embodiment 1 liver and gallbladder syndrome, adopt the effect of the described proportioning control of embodiment 6 bacterial enteritis very remarkable.
The clinical trial example:
Adopt the described Chinese medicine composition of embodiment 1 to do test when participating in the cintest in Hunan plant, be used for the treatment of the syndromic effect observation of speckle fork-tail silver xenocypris liver and gall.
, there is the speckle fork-tail silver xenocypris phase secondary disease of more than 30 mouthful of cage culture in June, 2011, their early stage, and the external sight of fish, than compared with normal, examines visible tail fin edge transparent, is commonly called as " fringing "; Fish swimming is undesired, dissect that visible gallbladder is bigger than normal, bile is denseer, liver enlargement, red and white, be graniphyric or bleach, and, with symptomes complices such as enteritis, hemorrhage, ulcer, the fish hepatic necrosis abscess of falling ill serious or be bean curd slag specimen pathological changes, be liver and gall syndrome of fish after diagnosing.
The mode that the described Chinese medicine composition of the embodiment of the present invention 1 is added to the 1g Chinese medicine composition with the per kilogram feedstuff is added in fish normal feedstuff (purchased from Tianjin rainbow feed corporation,Ltd), throw something and feed every day 3 times, using continuously 3 days is a course for the treatment of, after medication, the silver xenocypris fish is dead obviously reduces, from starting dead 60 tails of every mouthful of net cage every day, reduce in ten tails, use a course for the treatment of after the phenomena of mortality stop.Interval one Zhou Houzai throws something and feeds a course for the treatment of, and the after treatment effect strengthens the Fish Abwehrkraft des Koepers, and this type of disease does not occur in net cage then again, has played good prevention effect.
Piglet s colibacillosis:
In Tianjin, Piglet s colibacillosis is done by plant, is used for the treatment of the bacterial enteritis of fish, and main clinic symptoms shows as: slow in action, do not ingest, and abdominal distension, anus is outstanding, red and swollen etc.Get the sick fish of equivalent and tested, the described Chinese medicine composition of the embodiment of the present invention 6 and norfloxacin in treatment are used respectively in test.
The mode that the Chinese medicine composition group is added the 1g Chinese medicine composition with the per kilogram feedstuff is added in fish normal feedstuff (purchased from Tianjin rainbow feed corporation,Ltd), every fish daily ration of throwing something and feeding 3 times every day, and dosage, used 3 days continuously first; Norfloxacin (10%) group is thrown something and fed 3 times (300mg/d) every day, uses continuously 3 days.
After the course for the treatment of, use Chinese medicine composition group effective percentage to reach 94.3%, cure rate reaches 81.5%; Norfloxacin (10%) experimental group effective percentage is 71%, and cure rate is 66.2%.
Above-mentioned detailed description of this kind of fishing with antibacterial and anti-inflammation functions being carried out with Chinese medicine composition and preparation method thereof with reference to embodiment; illustrative rather than determinate; can list several embodiment according to institute's limited range; therefore in the variation and the modification that do not break away under general plotting of the present invention, within should belonging to protection scope of the present invention.