CN104383068A - High-efficiency, antiviral and bacteriostatic traditional Chinese veterinary medicine - Google Patents
High-efficiency, antiviral and bacteriostatic traditional Chinese veterinary medicine Download PDFInfo
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- CN104383068A CN104383068A CN201410750121.8A CN201410750121A CN104383068A CN 104383068 A CN104383068 A CN 104383068A CN 201410750121 A CN201410750121 A CN 201410750121A CN 104383068 A CN104383068 A CN 104383068A
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Abstract
The invention discloses a high-efficiency, antiviral and bacteriostatic traditional Chinese veterinary medicine, which is composed of the following raw materials in parts by weight: 80-100 parts of dandelion, 100-150 parts of liquorice, 80-100 parts of isatis root, 80-150 parts of honeysuckle, 60-80 parts of rheum officinale, 70-80 parts of radix bupleuri, 50-80 parts of radix sophorae flavescentis, 40-60 parts of cortex phellodendri, 30-50 parts of gallnut, 20-30 parts of clove, 60-100 parts of artemisia apiacea, 20-30 parts of cassia twig, 50-90 parts of Chinese parsnip root, 50-100 parts of coptis chinensis, 80-150 parts of the root of Chinese pulsatilla, 80-180 parts of folium isatidis, and 60-120 parts of mangnolia officinalis. The high-efficiency, antiviral and bacteriostatic traditional Chinese veterinary medicine disclosed by the invention is prepared by weighing, crushing, sieving and mixing various bulk drugs. By adopting purely natural Chinese herbal medicines, the high-efficiency, antiviral and bacteriostatic traditional Chinese veterinary medicine disclosed by the invention is easy in obtaining of the bulk drugs, low in cost, safe, and free from residue and any toxic and side effect to bodies of livestock and poultry. The traditional Chinese veterinary medicine is simple in preparation method and convenient to use and is applicable to large-scale production, popularization and application.
Description
Technical field
The present invention relates to a kind of herbal medicine, be specifically related to a kind of highly efficient anti-virus, antibacterial herbal medicine.
Background technology
Animal viral disease endangers larger, a modal class disease in disease.It not only can cause the large quantities of death of poultry, and livestock and poultry production performance reduces, and Animal product quality declines and directly affects income and the foreign trade of the people, and some zoonosis also threatens human health.Because virus mostly is mixed infection, belong in strict cell and deposit, its propagation relies on the biosynthesis of host cell significantly; The virus virus that medicine must optionally destroy or T suppression cell is inside and outside when treating, does not affect its normal metabolic processes for healthy cell.In conjunction with noresidue, without the requirement endangered, a lot of research have selected herbal medicine, and Chinese veterinarian prevents and treats animal viral disease in recent years certain achievement.
Summary of the invention
The object of the present invention is to provide a kind of highly efficient anti-virus, antibacterial herbal medicine, have good therapeutical effect to animal viral disease, and drug residue free, nothing endanger.
The object of the invention is with following technical proposals realize:
Highly efficient anti-virus, an antibacterial herbal medicine, be made up of the raw material of following weight portion: Herba Taraxaci 80 parts ~ 100 parts, 100 parts ~ 150 parts, Radix Glycyrrhizae, Radix Isatidis 80 parts ~ 100 parts, Flos Lonicerae 80 parts ~ 150 parts, Radix Et Rhizoma Rhei 60 parts ~ 80 parts, Radix Bupleuri 70 parts ~ 80 parts, Radix Sophorae Flavescentis 50 parts ~ 80 parts, Cortex Phellodendri 40 parts ~ 60 parts, Galla Chinensis 30 parts ~ 50 parts, Flos Caryophylli 20 parts ~ 30 parts, Herba Artemisiae Annuae 60 parts ~ 100 parts, Ramulus Cinnamomi 20 parts ~ 30 parts, Radix Saposhnikoviae 50 parts ~ 90 parts, Rhizoma Coptidis 50 parts ~ 100 parts, the Radix Pulsatillae 80 parts ~ 150 parts, Folium Isatidis 80 parts ~ 180 parts, Cortex Magnoliae Officinalis 60 parts ~ 120 parts.
Above-mentioned herbal medicine is powder, and preparation method comprises the following steps: get each crude drug, pulverizes, sieves, mixes and get final product.
Described grit number is excessively 60-100 order.
The present invention adopts Radix Glycyrrhizae, Radix Isatidis, Flos Lonicerae, Radix Et Rhizoma Rhei, Radix Bupleuri, Radix Sophorae Flavescentis, Cortex Phellodendri, Galla Chinensis, Flos Caryophylli, Herba Artemisiae Annuae, Ramulus Cinnamomi, Radix Saposhnikoviae, Rhizoma Coptidis, the Radix Pulsatillae, Folium Isatidis, Herba Taraxaci, Cortex Magnoliae Officinalis 17 taste Chinese herbal medicine to form a kind of highly efficient anti-virus, antibacterial herbal medicine.The present invention is pure natural Chinese herbal medicine, according to monarch principle composition of prescription.Radix Isatidis, Radix Glycyrrhizae, Radix Et Rhizoma Rhei in side are monarch drug, and energy heat-clearing and toxic substances removing, damp eliminating are except dry; Flos Lonicerae, Radix Bupleuri, Rhizoma Coptidis, Radix Sophorae Flavescentis, Cortex Phellodendri, Galla Chinensis are ministerial drug, energy anti-inflammation, removing pathogenic heat from blood and toxic substance from the body; Herba Artemisiae Annuae, Ramulus Cinnamomi, Radix Saposhnikoviae, the Radix Pulsatillae, Folium Isatidis, Herba Taraxaci, Cortex Magnoliae Officinalis for making medicine, can and middle emergency, lung moistening, removing toxic substances, coordinating the actions of various ingredients in a prescription; All medicines share, and play effect of anti-inflammation, heat-clearing and toxic substances removing, immunity moderation altogether; Wherein three taste medicine couplings are had synergistic corrosion virus effect by Radix Isatidis, Radix Glycyrrhizae, Rhizoma Coptidis all antibacterial, antiviral of energy.This medicine component is wide with the use of reaching antiviral scope, and bacteriostasis is strong, the effects such as therapeutic effect is good.
The present invention adopts pure natural Chinese herbal medicine, and crude drug is easy to get, cheap and safety, noresidue, without any side effects to poultry body.Herbal medicine preparation method of the present invention is simple, easy to use, is suitable for large-scale production and applies.
Detailed description of the invention
embodiment 1
Highly efficient anti-virus, an antibacterial herbal medicine, be made up of the raw material of following weight portion: Herba Taraxaci 80 parts ~ 100 parts, 100 parts ~ 150 parts, Radix Glycyrrhizae, Radix Isatidis 80 parts ~ 100 parts, Flos Lonicerae 80 parts ~ 150 parts, Radix Et Rhizoma Rhei 60 parts ~ 80 parts, Radix Bupleuri 70 parts ~ 80 parts, Radix Sophorae Flavescentis 50 parts ~ 80 parts, Cortex Phellodendri 40 parts ~ 60 parts, Galla Chinensis 30 parts ~ 50 parts, Flos Caryophylli 20 parts ~ 30 parts, Herba Artemisiae Annuae 60 parts ~ 100 parts, Ramulus Cinnamomi 20 parts ~ 30 parts, Radix Saposhnikoviae 50 parts ~ 90 parts, Rhizoma Coptidis 50 parts ~ 100 parts, the Radix Pulsatillae 80 parts ~ 150 parts, Folium Isatidis 80 parts ~ 180 parts, Cortex Magnoliae Officinalis 60 parts ~ 120 parts.
Above-mentioned herbal medicine is powder, and preparation method comprises the following steps: get each crude drug, pulverizes, and crosses 60-100 mesh sieve, mix homogeneously and get final product.
Certainly, highly efficient anti-virus of the present invention, antibacterial herbal medicine can adopt other conventional medicine preparation methoies to make other dosage form, as tablet, solution.
Wherein, Radix Isatidis: bitter in the mouth, cold, GUIXIN, lung.Liver, stomach warp; Energy heat clearing away, removing toxic substances, removing heat from blood, sore-throat relieving; Cure mainly anemopyretic cold, influenza, epidemic encephalitis, encephalitis b, major part pestilence, scarlet fever, wait disease separately; Modern pharmacology proves that Radix Isatidis has antibacterium, antiviral, antiendotoxin, the effect such as anticancer, has regulating action to immune system simultaneously.
Flos Lonicerae: have another name called Flos Lonicerae, Flos Lonicerae, Flos Lonicerae.Property, cold; Taste is bitter; Heat-clearing and toxic substances removing, eliminating pathogenic heat from blood to cure dysentery.With " heat clearing away of Flos Lonicerae energy and detoxify ", the wind heat of the clear part of the body cavity above the diaphragm housing the heart and lungs, removing summer-heat pyretic toxicity, cooling blood for hemostasis, for controlling pyretic toxicity key medicine just.Flos Lonicerae is containing luteolin lonicerin, cyclohexanhexanol etc. in addition, all has remarkable inhibitory action to various pathogens and influenza virus.
The Radix Pulsatillae: bitter in the mouth, cold in nature, main containing the composition such as buttercup glycoside protoanemonin and triterpene saponin pulchinenoside.Heat clearing and damp drying, removing pathogenic heat from blood and toxic substance from the body, cures mainly toxic-heat and blood stasis, tenesmus, damp-heat vaginal discharge, pyrexial malaria cold and heat." book on Chinese herbal medicine converges and says " records its energy " removing heat from blood, repercussive separate noxious dampness ".
Rhizoma Coptidis: be the rhizome of Rhizoma Imperatae section coptis plant Rhizoma Coptidis, Coptis deltoidea C.Y.Cheng et Hsiao or Coptis teeta; Containing alkaloids as various active compositions such as berberine, coptisine, epiberberine, obacunone; Rhizoma Coptidis nature and flavor are bitter, cold, GUIXIN, liver, stomach, large intestine channel; Energy clearing away heat-fire, dampness, removing toxic substances; Cure mainly the high heat that calentura heresy enters heart channel, irritated, the damp and hot feeling of stuffiness in chest, has loose bowels, dysentery, the vexed insomnia of hyperactivity of heart-fire, gastropyretic vomiting, rapid digestion of food and polyorexia, liver-fire conjunctival congestion and swelling pain, and pathopyretic ulcer, furunculosis septicemia, gingival swelling and pain, aphtha of the mouth and tongue, hemorrhoidal bleeding, eczema, scalds; Modern pharmacology proves that Rhizoma Coptidis has an impact to blood circulation, nervous system, also has the effects such as antimicrobial, protozoacide, antiulcer, antiviral, antiinflammatory, antitumor, blood sugar lowering, anticoagulant.
Radix Glycyrrhizae: be the root and rhizome of pulse family glycyrrhiza genus Radix Glycyrrhizae, smooth bark Radix Glycyrrhizae, Glycyrrhiza inflata Bat.; Containing triterpene saponin as glycyrrhizin, Glycyrrhiza uralensis Fisch. saponin A, B etc., flavone compound is as 4',7-Dihydroxyflavanone, liquirtin etc., coumarin kind compound is as glycycoumarin, glycyol etc., alkaloids is as quinolines, iloquinoline derivative etc., polysaccharide, as Radix Glycyrrhizae glucosan GBW, Angelica Polysaccharide UA, UB, UC etc., also contains the plurality of active ingredients such as Radix Glycyrrhizae benzofuran, n-tricosane; Nature and flavor are sweet, flat, return spleen, stomach, the heart, lung meridian; Can and middle emergency, lung moistening, removing toxic substances, coordinating the actions of various ingredients in a prescription; Process with controlling weakness of the spleen and stomach, asthenia lack of appetite, stomachache loose stool, the anxious pain of extremity contraction, cardiopalmus, hysteria, consumptive lung disease cough, raw with controlling laryngopharynx swelling and pain, carbuncle pyogenic infections from tumour or sore, infantile carbuncle and medicine, alimentary toxicosis etc.; Modern pharmacology proves the effects such as Radix Glycyrrhizae has antimicrobial, antiinflammatory, antitussive, eliminates the phlegm, antitumor, mutation, antioxidation, has regulating action to digestive system, cardiovascular system, reproductive system and brain, renal function etc.
embodiment 2
Highly efficient anti-virus, an antibacterial herbal medicine, be made up of the raw material of following weight portion: Herba Taraxaci 80 parts, 150 parts, Radix Glycyrrhizae, Radix Isatidis 100 parts, Flos Lonicerae 80 parts, Radix Et Rhizoma Rhei 70, Radix Bupleuri 70, Radix Sophorae Flavescentis 50 parts, Cortex Phellodendri 45 parts, Galla Chinensis 30 parts, Flos Caryophylli 30 parts, Herba Artemisiae Annuae 60 parts, Ramulus Cinnamomi 30 parts, Radix Saposhnikoviae 50 parts, Rhizoma Coptidis 50 parts, the Radix Pulsatillae 80 parts, Folium Isatidis 80 parts, Cortex Magnoliae Officinalis 60 parts.Preparation method comprises the following steps: accurately get each taste crude drug according to parts by weight, pulverizes, and crosses 60 mesh sieves and get final product.
embodiment 3
Highly efficient anti-virus, an antibacterial herbal medicine, be made up of the raw material of following weight portion: Herba Taraxaci 100 parts, 120 parts, Radix Glycyrrhizae, Radix Isatidis 80 parts, Flos Lonicerae 100 parts, Radix Et Rhizoma Rhei 80 parts, Radix Bupleuri 70 parts, Radix Sophorae Flavescentis 60 parts, Cortex Phellodendri 40 parts, Galla Chinensis 50 parts, Flos Caryophylli 20 parts, Herba Artemisiae Annuae 80 parts, Ramulus Cinnamomi 30 parts, Radix Saposhnikoviae 70 parts, Rhizoma Coptidis 100 parts, the Radix Pulsatillae 120 parts, Folium Isatidis 150 parts, Cortex Magnoliae Officinalis 100 parts.Preparation method comprises the following steps: accurately get each taste crude drug according to parts by weight, pulverizes, and crosses 80 mesh sieves and get final product.
embodiment 4
Highly efficient anti-virus, an antibacterial herbal medicine, be made up of the raw material of following weight portion: Herba Taraxaci 100,100 parts, Radix Glycyrrhizae, Radix Isatidis 90 parts, Flos Lonicerae 150 parts, Radix Et Rhizoma Rhei 60 parts, Radix Bupleuri 80 parts, Radix Sophorae Flavescentis 80 parts, Cortex Phellodendri 60 parts, Galla Chinensis 30 parts, Flos Caryophylli 30 parts, Herba Artemisiae Annuae 100 parts, Ramulus Cinnamomi 20 parts, Radix Saposhnikoviae 90 parts, Rhizoma Coptidis 150 parts, the Radix Pulsatillae 150 parts, Folium Isatidis 180 parts, Cortex Magnoliae Officinalis 120 parts.Preparation method comprises the following steps: accurately get each taste crude drug according to parts by weight, pulverizes, 100 sieves and get final product of looking over so as to check.
In herbal medicine embodiment 5-15 of the present invention, each raw material weight number is in table 1, and in embodiment 16-26, each raw material weight number is in table 2, the other the same as in Example 2.
each raw material weight number table in table 1 herbal medicine of the present invention embodiment 5-15
each raw material weight number table in table 2 herbal medicine of the present invention embodiment 16-26
test example 1
Use concrete description of test effect of the present invention below:
Test material: the animal in spite of illness randomly drawing bacteriological infection, gets pathological material of disease and makes for examination bacterium liquid, trial drug: the herbal medicine, the commercially available antibacterial and antiviral drug (astragalus polysaccharides powder, 100g/ bag, Yi, a legendary monarch of Youqiong State in the xia Dynasty pharmacy behind Zhengzhou) that obtain according to embodiment 2-4.
Test method
Filter paper enzyme measures bacteriostasis: the circular filter paper sheet of diameter 6mm, put into above four kinds of medicines 16 hours, at 121 DEG C, moist heat sterilization is for subsequent use.Get and respectively get 0.5ml for examination bacterium liquid, get agar culture medium, superclean bench is made containing bacterium dull and stereotyped, the filter paper got containing leachate is attached on flat board by suitable spacing, and every ware pastes 5, operation repetitive 4 times.37 DEG C of constant incubators cultivate 48 hours, and after mensuration 24h, 48h, the diameter of the inhibition zone of filter paper, compares fungistatic effect in table 3.
Minimum inhibitory concentration (Mic) measures: preparation agar culture medium, accurately measure 9ml and divide threading test tube, accurately add 8%, 4%, 2%, 1%, 0.5%, 0.25% medicine series concentration 1ml, be made into serial culture base, 121 DEG C of high pressure moist heat sterilizations, every series of vaccinations one group of bacterium liquid after cold preservation, every series does 3 repetitions, and 37 DEG C of constant incubators cultivate 48 hours, observes growth situation, there is no the least concentration of bacteria growing completely for minimum inhibitory concentration, in table 4.
Herbal medicine prepared by table 3 the present invention is to the inhibition for examination strain
Herbal medicine minimum inhibitory concentration prepared by table 4 the present invention
Above-mentioned the pharmacological results shows that Chinese medicine composition of the present invention has stronger bacteriostasis, and embodiment 3 effect is best.
test example 2
1. the test of pair infectious laryngotracheitis of chicken
Certain chicken farm, there is chicken group Depression of spirits in 40 age in days chickens, feather pine is random, son of haveing loose bowels, catchbreath, mortality rate 8%, being judged to infectious laryngotracheitis of chicken through cuing open inspection, taking herbal medicine prepared by the embodiment of the present invention 3, being used in conjunction 5 days, mortality rate reduces, mental restoration is normal, and respiratory symptom is alleviated, and illustrates that herbal medicine of the present invention plays good therapeutic effect.
2. the test of pair Porcine Circovirus
Certain pig farm, 12 week age, there is appetite and reduces in grower pigs, body temperature raises, dyspnea, part pig generation subcutaneous dropsy, there is aubergine pathological changes speckle in skin, turns out to be Porcine Circovirus infection through cuing open inspection, take herbal medicine prepared by the embodiment of the present invention 3, be used in conjunction 5 days, the appetite mental status takes a turn for the better, and body temperature is normal, subcutaneous redness and speckle disappear, and illustrate that herbal medicine of the present invention plays good therapeutic effect.
Claims (4)
1. highly efficient anti-virus, an antibacterial herbal medicine, is characterized in that: be made up of the raw material of following weight portion: Herba Taraxaci 80 parts ~ 100 parts, 100 parts ~ 150 parts, Radix Glycyrrhizae, Radix Isatidis 80 parts ~ 100 parts, Flos Lonicerae 80 parts ~ 150 parts, Radix Et Rhizoma Rhei 60 parts ~ 80 parts, Radix Bupleuri 70 parts ~ 80 parts, Radix Sophorae Flavescentis 50 parts ~ 80 parts, Cortex Phellodendri 40 parts ~ 60 parts, Galla Chinensis 30 parts ~ 50 parts, Flos Caryophylli 20 parts ~ 30 parts, Herba Artemisiae Annuae 60 parts ~ 100 parts, Ramulus Cinnamomi 20 parts ~ 30 parts, Radix Saposhnikoviae 50 parts ~ 90 parts, Rhizoma Coptidis 50 parts ~ 100 parts, the Radix Pulsatillae 80 parts ~ 150 parts, Folium Isatidis 80 parts ~ 180 parts, Cortex Magnoliae Officinalis 60 parts ~ 120 parts.
2. highly efficient anti-virus, antibacterial herbal medicine as claimed in claim 1, is characterized in that: its dosage form is powder.
3. the preparation method of highly efficient anti-virus as claimed in claim 1 or 2, antibacterial herbal medicine, is characterized in that comprising the following steps: get each crude drug, pulverizes, sieves, mixes and get final product.
4. the preparation method of highly efficient anti-virus as claimed in claim 3, antibacterial herbal medicine, is characterized in that: crossing grit number is 60-100 order.
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| CN104383068B (en) | 2017-11-21 |
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Address after: 451164 eastern side of Donggang Avenue, Zhengzhou airport economic comprehensive test area, Henan Applicant after: Henan Hou Yi Industry Group Co., Ltd. Address before: 451100 Xingang, Henan, Xinzheng Port Road East Side Applicant before: Zhengzhou Houyi Pharmaceutical Co., Ltd. |
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Effective date of registration: 20211216 Address after: 463000 Zhumadian Industrial Park, Henan Province Patentee after: HENAN HOUYI PHARMACY CO.,LTD. Address before: 451164 east side of Donggang Avenue, airport economic comprehensive experimental zone, Zhengzhou City, Henan Province Patentee before: HENAN HOUYI INDUSTRIAL GROUP CO.,LTD. |