CN102813850B - Traditional Chinese medicine composition for preventing and treating poultry coccidiosis and preparation method of traditional Chinese medicine composition - Google Patents
Traditional Chinese medicine composition for preventing and treating poultry coccidiosis and preparation method of traditional Chinese medicine composition Download PDFInfo
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Abstract
The invention relates to a traditional Chinese medicine composition for preventing and treating poultry coccidiosis and a preparation method of the traditional Chinese medicine composition. The medicine materials of the traditional Chinese medicine composition comprise antifebrile dichroa, radix sophorae flavescentis, flos chrysanthemi indici, garlic, cogongrass rhizome, carbonized sanguisorba root, hairyvein agrimony, golden cypress, dandelion, rhizoma atractylodis, fennel, astragalus mongholicus, coptis chinensis and radix bupleuri. By using the traditional Chinese medicine composition, the purpose of preventing and treating coccidiosis in chicken can be effectively achieved in the aspects of expelling parasite, preventing malaria, hemostasis, cooling blood, clearing heat, diminishing inflammation and nourishing. In addition, two technologies of extraction and superfine grinding are adopted in a manufacturing process so that the utilization rate and biological solubility of the traditional Chinese medicines are significantly improved. Water or mixed materials can be taken during administration so that the clinical application is more convenient. Furthermore, the traditional Chinese medicine composition is prepared from pure traditional Chinese medicines, has no drug residue and has no toxic and side effects on an organism.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition and preparation method thereof, specifically be a kind of Chinese medicine composition of preventing and treating birds coccidiosis and preparation method thereof.
Background technology
Along with China's aviculture is gradually to scale, intensive, modernization future development, large-scale raiser or the development of cultivation group are comparatively rapid, cultivation batch and density also more and more concentrated, economic benefit is larger, simultaneously, more be conducive to the concentrated prevention and control of disease, bacillary and viral disease is effectively controlled, but the harm of parasitic disease becomes increasingly conspicuous, for example: the white comb that leucocyte protozoon causes, the coccidiosis that all kinds of coccidiosiss cause etc., especially coccidiosis, not only cause the loss of nutritional labeling in poultry body, serious also can cause the death of large batch, the coccidium infection that particularly Eimeria Tenella and murder by poisoning eimeria tenella cause, sickness rate and the fatality rate of the young chicken of 10～30 Japanese instar chicklings or 35～60 ages in days can be up to 80%, economic loss is huge, be endanger at present avian production especially broiler produce in the most serious parasitic disease.
To so far, the medicine for the treatment of coccidiosis of domestic fowls on market is numerous, mainly with chemicals, be main greatly, due to the extensive application of these medicines, easily produce drug resistance and drug residue, had a strong impact on the foreign exchange earning of China's birds product, not only cause economic loss, and be detrimental to health, so it is little to seek a kind of safety, good effect, toxic and side effects, the micronizing tcm product that is difficult for producing drug resistance and can treats coccidiosis of domestic fowls is current aviculture problem anxious to be resolved.
Summary of the invention
The object of the invention is the deficiency for solving the problems of the technologies described above, a kind of Chinese medicine composition of preventing and treating birds coccidiosis and preparation method thereof is provided, this Chinese medicine composition composition formula forms scientific and reasonable, can effectively treat and prevent coccidiosis of domestic fowls, and easy to use, after medication, have no side effect and drug residue.
The present invention is the deficiency solving the problems of the technologies described above, the technical scheme adopting is: a kind of Chinese medicine composition of preventing and treating birds coccidiosis, its crude drug is comprised of Radix Dichroae, Radix Sophorae Flavescentis, Flos Chrysanthemi Indici, Bulbus Allii, Rhizoma Imperatae, charred Radix Sanguisorbae, Herba Agrimoniae, Cortex Phellodendri, Herba Taraxaci, Rhizoma Atractylodis, Fructus Foeniculi, the Radix Astragali, Rhizoma Coptidis and Radix Bupleuri, and the parts by weight of each crude drug are 5～20 parts.
The parts by weight of each crude drug are: 17 parts of Radix Dichroaes, 8 parts of Radix Sophorae Flavescentiss, 9 parts of Flos Chrysanthemi Indicis, 5 parts, Bulbus Allii, 8 parts of Rhizoma Imperataes, 7 parts of charred Radix Sanguisorbae, 7 parts of Herba Agrimoniaes, 5 parts of Cortex Phellodendris, 5 parts of Herba Taraxacis, 6 parts of Rhizoma Atractylodis, 5 parts of Fructus Foeniculi, 8 parts of the Radixs Astragali, 5 parts of Rhizoma Coptidis, 5 parts of Radix Bupleuri.
A preparation method of preventing and treating the Chinese medicine composition of birds coccidiosis, comprises the following steps:
(1), get by weight each 5～20 parts of Radix Dichroae, Radix Sophorae Flavescentis, Flos Chrysanthemi Indici, Bulbus Allii, Rhizoma Imperatae, charred Radix Sanguisorbae, Herba Agrimoniae, Cortex Phellodendri, Herba Taraxaci, Rhizoma Atractylodis, Fructus Foeniculi, the Radix Astragali, Rhizoma Coptidis and Radix Bupleuri, by above-mentioned raw material of Chinese medicine, rinsing is clean respectively, and to control temperature be 100 ℃, dry 1～1.5h;
(2), raw material of Chinese medicine dried in step (1) is pulverized respectively and crossed 24～80 mesh sieves, make each raw material of Chinese medicine coarse powder, standby;
(3), get Radix Dichroae coarse powder and add in extraction pot, and add the boiling water of 15～25 times of Radix Dichroae coarse powder weight, using lactic acid to adjust pH value is 6.5, then extraction pot is placed in to 100 ℃ of water-baths, stirs 2～3h, stir and finish rear filtration, obtain extracting solution one time, filtering residue takes out standby;
(4), filtering residue that step (3) is obtained adds extraction pot, according to the method for step (3), extracts once again, obtains secondary raffinate, extracting solution and secondary raffinate merged to concentrated, the dry Radix Dichroae dry powder that obtains;
(5), get after all the other Chinese medicine coarse powder except Radix Dichroae mix and again pulverize, cross 100 mesh sieves, obtain raw material of Chinese medicine fine powder;
(6), get the raw material of Chinese medicine fine powder mix homogeneously obtaining in Radix Dichroae dry powder that step (4) makes and step (5), pulverize and cross 100 mesh sieves, then carry out micronizing, after 325 mesh sieves, obtain Chinese medicine composition.
beneficial effect
(1) Radix Dichroae, in Chinese medicine composition composition formula of the present invention and Radix Sophorae Flavescentis, as principal agent, have and significantly kill coccidiosis effect; Rhizoma Imperatae, charred Radix Sanguisorbae, Herba Agrimoniae all have removing heat from blood, anastalsis, particularly Herba Agrimoniae and also have Blood clotting, and three's action compensating can obviously change the hemafecia number of coccidiosis chicken; Bulbus Allii has bactericidal antiphlogistic effect, can effectively alleviate the damage of disease chicken intestinal mucosa and without any side effects; Cortex Phellodendri, Herba Taraxaci, Rhizoma Coptidis, Radix Bupleuri all have heat-clearing and toxic substances removing, the effect of soothing liver-QI yang invigorating, particularly Herba Taraxaci also has the effect of inducing diuresis for treating stranguria syndrome, Cortex Phellodendri, Herba Taraxaci, Rhizoma Coptidis, Radix Bupleuri four taste Chinese medicines coordinate the recovery that can improve disease Intestinum Gallus domesticus road and liver digestive function on the one hand with Bulbus Allii, can strengthen the excretory function of kidney on the other hand, thereby recover chicken group's feed intake; Rhizoma Atractylodis, Fructus Foeniculi, the Radix Astragali have the effect of invigorating QI to consolidate the body surface resistance, stomach function regulating spleen invigorating, cold expelling granulation promoting, and three taste medicines cooperatively interact, and can effectively improve chicken coccidiosis treatment later stage chicken group's nutriture and the recovery of body constitution.Each prescription coordinates and can effectively realize the object of preventing and treating chicken coccidiosis from anthelmintic preventing the attack (or recurrence) of malaria, hemostasis removing heat from blood, heat clearing and inflammation relieving and nourishing aspect above.
(2), the processing technology of Chinese medicine composition of the present invention adopts and extracts and two kinds of technology of micronizing, utilization rate and the biological solubility of Chinese medicine have been significantly improved, in medication process, can drink water or spice, in clinical practice more for convenience, and belong to pure Chinese medicine composition, without any drug residue, without any side effects to body.
The specific embodiment
Below specific embodiments of the invention:
embodiment 1
A preparation method of preventing and treating the Chinese medicine composition of birds coccidiosis, comprises the following steps:
(1), get by weight 17 parts of Radix Dichroaes, 8 parts of Radix Sophorae Flavescentiss, 9 parts of Flos Chrysanthemi Indicis, 5 parts, Bulbus Allii, 8 parts of Rhizoma Imperataes, 7 parts of charred Radix Sanguisorbae, 7 parts of Herba Agrimoniaes, 5 parts of Cortex Phellodendris, 5 parts of Herba Taraxacis, 6 parts of Rhizoma Atractylodis, 5 parts of Fructus Foeniculi, 8 parts of the Radixs Astragali, 5 parts of Rhizoma Coptidis, 5 parts of Radix Bupleuri, by above-mentioned raw material of Chinese medicine, rinsing is clean respectively, and to control temperature be 100 ℃, dry 1.5h;
(2), raw material of Chinese medicine dried in step (1) is pulverized respectively and crossed 24 mesh sieves, make raw material of Chinese medicine coarse powder;
(3), get Radix Dichroae coarse powder and add in extraction pot, and add the boiling water of 20 times of Radix Dichroae coarse powder weight, using lactic acid to adjust pH value is 6.5, then extraction pot is placed in to 100 ℃ of water-baths, stirs 2h, stir and finish rear filtration, obtain extracting solution one time, filtering residue takes out standby;
(4), filtering residue that step (3) is obtained adds extraction pot, the leaching process of repeating step (3), obtains secondary raffinate, extracting solution and secondary raffinate is merged to the concentrated Radix Dichroae dry powder that obtains;
(5), get after other Chinese medicine coarse powder except Radix Dichroae mixes and pulverize, cross 100 mesh sieves, obtain raw material of Chinese medicine fine powder;
(6), get the raw material of Chinese medicine fine powder mix homogeneously obtaining in Radix Dichroae dry powder that step (4) makes and step (5), pulverize and cross 100 mesh sieves, then carry out micronizing, after 325 mesh sieves, obtain Chinese medicine composition.
embodiment 2
A preparation method of preventing and treating the Chinese medicine composition of birds coccidiosis, comprises the following steps:
(1), get by weight 5 parts of Radix Dichroaes, 14 parts of Radix Sophorae Flavescentiss, 20 parts of Flos Chrysanthemi Indicis, 10 parts, Bulbus Allii, 14 parts of Rhizoma Imperataes, 5 parts of charred Radix Sanguisorbae, 20 parts of Herba Agrimoniaes, 20 parts of Cortex Phellodendris, 14 parts of Herba Taraxacis, 10 parts of Rhizoma Atractylodis, 10 parts of Fructus Foeniculi, 5 parts of the Radixs Astragali, 20 parts of Rhizoma Coptidis, 14 parts of Radix Bupleuri, by above-mentioned raw material of Chinese medicine, rinsing is clean respectively, and to control temperature be 100 ℃, dry 1h;
(2), raw material of Chinese medicine dried in step (1) is pulverized respectively and crossed 60 mesh sieves, make raw material of Chinese medicine coarse powder;
(3), get Radix Dichroae coarse powder and add in extraction pot, and add the boiling water of 14 times of Radix Dichroae coarse powder weight, using lactic acid to adjust pH value is 6.5, then extraction pot is placed in to 100 ℃ of water-baths, stirs 3h, stir and finish rear filtration, obtain extracting solution one time, filtering residue takes out standby;
(4), filtering residue that step (3) is obtained adds extraction pot, the leaching process of repeating step (3), obtains secondary raffinate, extracting solution and secondary raffinate is merged to the concentrated Radix Dichroae dry powder that obtains;
(5), get after other Chinese medicine coarse powder except Radix Dichroae mixes and pulverize, cross 100 mesh sieves, obtain raw material of Chinese medicine fine powder;
(6), get the raw material of Chinese medicine fine powder mix homogeneously obtaining in Radix Dichroae dry powder that step (4) makes and step (5), pulverize and cross 100 mesh sieves, then carry out micronizing, after 325 mesh sieves, obtain Chinese medicine composition.
embodiment 3
A preparation method of preventing and treating the Chinese medicine composition of birds coccidiosis, comprises the following steps:
(1), get by weight 8 parts of Radix Dichroaes, 20 parts of Radix Sophorae Flavescentiss, 14 parts of Flos Chrysanthemi Indicis, 20 parts, Bulbus Allii, 5 parts of Rhizoma Imperataes, 14 parts of charred Radix Sanguisorbae, 14 parts of Herba Agrimoniaes, 14 parts of Cortex Phellodendris, 20 parts of Herba Taraxacis, 15 parts of Rhizoma Atractylodis, 14 parts of Fructus Foeniculi, 15 parts of the Radixs Astragali, 14 parts of Rhizoma Coptidis, 20 parts of Radix Bupleuri, by above-mentioned raw material of Chinese medicine, rinsing is clean respectively, and to control temperature be 100 ℃, dry 1.5h;
(2), raw material of Chinese medicine dried in step (1) is pulverized respectively and crossed 80 mesh sieves, make raw material of Chinese medicine coarse powder;
(3), get Radix Dichroae coarse powder and add in extraction pot, and add the boiling water of 25 times of Radix Dichroae coarse powder weight, using lactic acid to adjust pH value is 6.5, then extraction pot is placed in to 100 ℃ of water-baths, stirs 2h, stir and finish rear filtration, obtain extracting solution one time, filtering residue takes out standby;
(4), filtering residue that step (3) is obtained adds extraction pot, the leaching process of repeating step (3), obtains secondary raffinate, extracting solution and secondary raffinate is merged to the concentrated Radix Dichroae dry powder that obtains;
(5), get after other Chinese medicine coarse powder except Radix Dichroae mixes and pulverize, cross 100 mesh sieves, obtain raw material of Chinese medicine fine powder;
(6), get the raw material of Chinese medicine fine powder mix homogeneously obtaining in Radix Dichroae dry powder that step (4) makes and step (5), pulverize and cross 100 mesh sieves, then carry out micronizing, after 325 mesh sieves, obtain Chinese medicine composition.
embodiment 4
A preparation method of preventing and treating the Chinese medicine composition of birds coccidiosis, comprises the following steps:
(1), get by weight 14 parts of Radix Dichroaes, 5 parts of Radix Sophorae Flavescentiss, 5 parts of Flos Chrysanthemi Indicis, 14 parts, Bulbus Allii, 20 parts of Rhizoma Imperataes, 20 parts of charred Radix Sanguisorbae, 5 parts of Herba Agrimoniaes, 10 parts of Cortex Phellodendris, 20 parts of Herba Taraxacis, 20 parts of Rhizoma Atractylodis, 20 parts of Fructus Foeniculi, 20 parts of the Radixs Astragali, 10 parts of Rhizoma Coptidis, 10 parts of Radix Bupleuri, by above-mentioned raw material of Chinese medicine, rinsing is clean respectively, and to control temperature be 100 ℃, dry 1h;
(2), raw material of Chinese medicine dried in step (1) is pulverized respectively and crossed 70 mesh sieves, make raw material of Chinese medicine coarse powder;
(3), get Radix Dichroae coarse powder and add in extraction pot, and add the boiling water of 20 times of Radix Dichroae coarse powder weight, using lactic acid to adjust pH value is 6.5, then extraction pot is placed in to 100 ℃ of water-baths, stirs 2h, stir and finish rear filtration, obtain extracting solution one time, filtering residue takes out standby;
(4), filtering residue that step (3) is obtained adds extraction pot, the leaching process of repeating step (3), obtains secondary raffinate, extracting solution and secondary raffinate is merged to the concentrated Radix Dichroae dry powder that obtains;
(5), get after other Chinese medicine coarse powder except Radix Dichroae mixes and pulverize, cross 100 mesh sieves, obtain raw material of Chinese medicine fine powder;
(6), get the raw material of Chinese medicine fine powder mix homogeneously obtaining in Radix Dichroae dry powder that step (4) makes and step (5), pulverize and cross 100 mesh sieves, then carry out micronizing, after 325 mesh sieves, obtain Chinese medicine composition.
animal experiment
Test method is: 15 age in days healthy chickens are moved into experimental animal room, divide at random 5 groups, every group of 3 cages, 10 of every cage mounteds, body weight difference ± 5g between each cage.
Processing method is respectively organized in test: test group 1 spice adds Chinese medicine of the present invention, and every 200 ㎏ feedstuffs add Chinese medicine 1 ㎏ of the present invention; Test group 2 drinking-water add Chinese medicine of the present invention, and every 800 ㎏ drinking-water add Chinese medicine 1 ㎏ of the present invention; 0.5% diclazuril pre-mixing agent (Henan Krona Kang Di feed corporation,Ltd prepares and provides) is provided test group 3, and every 1 ㎏ feedstuff adds 0.2g diclazuril pre-mixing agent, mixed feeding administration; Test group 4, for infecting matched group, only infects not administration, feeds and does not contain normal feedstuff and the drinking-water of medicine; Test group 5 is normal healthy controls group, and not infecting feeds simultaneously does not contain normal feedstuff and the drinking-water of medicine.Test group 1,2 and 3, all since 16 age in days administrations, continuous 7 days, is fed afterwards and is not contained normal feedstuff and the drinking-water of medicine.
During 18 age in days, except normal healthy controls group, after toxicity test, other respectively organize every chicken peroral infection Eimeria Tenella Sporulated Oocysts 6 * 10
4individual contamination.
Process of the test: after 18 ages in days contaminations, Continuous Observation 7 days, every day observed and recorded chicken incidence, hemafecia and death toll etc.The feces of collecting every group of chicken during 25 age in days carries out egg capsule counting, during 26 age in days, each component another name weighs and all cuts open and kill, the weightening finish of observed and recorded test chicken and caecum lesion situation, the egg sac number (OPG) with Maxwell method calculating cecal content, calculates egg capsule value by field, angle therapy for clearing away heat.According to indexs such as survival rate, the relative weight gain rate, pathological changes value, anticoccidial index (ACI), egg capsule values, evaluate the curative effect of respectively organizing medicine.
The Chinese medicine composition that uses the embodiment of the present invention 1 to make carries out zoopery, and therapeutic effect is as shown in table 1:
The Chinese medicine composition that uses the embodiment of the present invention 2 to make carries out zoopery, and therapeutic effect is as shown in table 2:
The Chinese medicine composition that uses the embodiment of the present invention 3 to make carries out zoopery, and therapeutic effect is as shown in table 3:
The Chinese medicine composition that uses the embodiment of the present invention 4 to make carries out zoopery, and therapeutic effect is as shown in table 4:
By above-mentioned four result of the tests, all can find out: use 2 group survival rates of Chinese medicine composition of the present invention higher, body weight is also significantly increased; pathological changes value has obvious reduction; and the egg capsule of cecal content kills except more thorough; and anticoccidial index is all greater than 180; belong to efficient medicine, is better than diclazuril group.
Clinical trial example 1:
In August, 2011, on the occasion of high temperature and rainy, wet damp season, more than 7000 chicken of Mengjin County broiler breeding factory 20 ages in days, approximately there are 1600 morbidities, main clinic symptoms: sick Chicken Wings is sagging, feather is fluffy and disorderly, inappetence, cockscomb are pale, the unable paralysis of bipod does not play, sinks into sleep state, hides a necking down, closes one's eyes.Sick Sanguis Gallus domesticus just, have loose bowels, the dry rare normally slightly a small amount of blood of feces during beginning, the band blood of having loose bowels subsequently, cloacal aperture feather around by liquid discharges pollute, adhesion, suffer from chicken and become thin gradually, indivedual sick Chicken Wings generation paresis, anemia.
Cuing open inspection changes: the night blindness intestinal wall of dying of illness thickens, pale, inside has purulence content; In caecum, have blood clot, intestinal wall has a large amount of chicken coccidiosis tuberositys red and white.Indivedual sick chickens are cutd open inspection and see caecum chap, swelling, air-blowing, severe haemorrhage, and intestinal mucosa is hemorrhage and downright bad, and intestinal contents blood sample includes the mucosa that necrosis is stripped off, or is mixed with the cheesy solidifying bolt of blood.
Microscopy is observed: get disease chicken stool examination, find coccidian oocyst, further be diagnosed as the Caecum Coccidiosis of chicken, use Chinese medicine composition of the present invention, adopt spice administration, within front 1-3 days, by this Chinese medicine composition spice of 1 ㎏ 150 ㎏, treat, within rear 4-7 days, press this Chinese medicine composition spice of 1 ㎏ 250 ㎏, be used in conjunction 7.Through observing, by the 4th day, most of sick chicken mental restoration is normal, and hemafecia phenomenon is obviously alleviated, and sick chicken death phenomenon is basic controlling also, in the time of the 7th day, jumpbogroup chicken manure just recovers normal, substantially without hemafecia phenomenon, meanwhile, the chicken appetite of mining massively obviously increases, as can be seen here, this chicken group's coccidiosis is thoroughly controlled.
Clinical trial example 2:
In July, 2011, little Miao town, Feixi County, Hefei ,Anhui blue or green foot chicken cultivation factory, the blue or green foot chicken of the normal livestock on hand 70,000 plumage commodity of this factory, the 15-25 age in days that cause because of small intestinal coccidiosis or caecum coccidiosis annual summer and the chicken group of 35-42 age in days are broken out coccidiosis, cause every batch of death to reach 15%, postpone listing age in days, the price of deed reduces, low in economic efficiency, and spend a large amount of expensess for medicine for this reason, the coccidiosis medicine expenditure of about 0.35 yuan (every chicken) but to improve effect general; Entered chickling 50,000 plumages on July 3, and start to admix this invention Chinese medicine composition at 10 ages in days in complete feedstuff, by every 1000 kilograms of feedstuffs, add 1.5 kilograms of the present compositions, use continuously, uninterrupted, when delivering for sale, there is not coccidium infection, and in whole breeding cycle, do not add any Western medicine anticoccidial drug, and the expense expenditure of this invention compositions is lower, and economic benefit is very obvious.
Claims (2)
1. a preparation method of preventing and treating the Chinese medicine composition of birds coccidiosis, is characterized in that: comprise the following steps:
(1), get by weight each 5～20 parts of Radix Dichroae, Radix Sophorae Flavescentis, Flos Chrysanthemi Indici, Bulbus Allii, Rhizoma Imperatae, charred Radix Sanguisorbae, Herba Agrimoniae, Cortex Phellodendri, Herba Taraxaci, Rhizoma Atractylodis, Fructus Foeniculi, the Radix Astragali, Rhizoma Coptidis and Radix Bupleuri, by above-mentioned raw material of Chinese medicine, rinsing is clean respectively, and to control temperature be 100 ℃, dry 1～1.5h;
(2), raw material of Chinese medicine dried in step (1) is pulverized respectively and crossed 24～80 mesh sieves, make each raw material of Chinese medicine coarse powder, standby;
(3), get Radix Dichroae coarse powder and add in extraction pot, and add the boiling water of 15～25 times of Radix Dichroae coarse powder weight, using lactic acid to adjust pH value is 6.5, then extraction pot is placed in to 100 ℃ of water-baths, stirs 2～3h, stir and finish rear filtration, obtain extracting solution one time, filtering residue takes out standby;
(4), filtering residue that step (3) is obtained adds extraction pot, according to the method for step (3), extracts once again, obtains secondary raffinate, extracting solution and secondary raffinate merged to concentrated, the dry Radix Dichroae dry powder that obtains;
(5), get after all the other Chinese medicine coarse powder except Radix Dichroae mix and again pulverize, cross 100 mesh sieves, obtain raw material of Chinese medicine fine powder;
(6), get the raw material of Chinese medicine fine powder mix homogeneously obtaining in Radix Dichroae dry powder that step (4) makes and step (5), pulverize and cross 100 mesh sieves, then carry out micronizing, after 325 mesh sieves, obtain Chinese medicine composition.
2. a kind of preparation method of preventing and treating the Chinese medicine composition of birds coccidiosis as claimed in claim 1, is characterized in that: comprise the following steps:
(1), get by weight 5 parts of 17 parts of Radix Dichroaes, 8 parts of Radix Sophorae Flavescentiss, 9 parts of Flos Chrysanthemi Indicis, 5 parts, Bulbus Allii, 8 parts of Rhizoma Imperataes, 7 parts of charred Radix Sanguisorbae, 7 parts of Herba Agrimoniaes, 5 parts of Cortex Phellodendris, 5 parts of Herba Taraxacis, 6 parts of Rhizoma Atractylodis, 5 parts of Fructus Foeniculi, 8 parts of the Radixs Astragali, 5 parts of Rhizoma Coptidis and Radix Bupleuri, by above-mentioned raw material of Chinese medicine, rinsing is clean respectively, and to control temperature be 100 ℃, dry 1～1.5h;
(2), raw material of Chinese medicine dried in step (1) is pulverized respectively and crossed 24～80 mesh sieves, make each raw material of Chinese medicine coarse powder, standby;
(3), get Radix Dichroae coarse powder and add in extraction pot, and add the boiling water of 15～25 times of Radix Dichroae coarse powder weight, using lactic acid to adjust pH value is 6.5, then extraction pot is placed in to 100 ℃ of water-baths, stirs 2～3h, stir and finish rear filtration, obtain extracting solution one time, filtering residue takes out standby;
(4), filtering residue that step (3) is obtained adds extraction pot, according to the method for step (3), extracts once again, obtains secondary raffinate, extracting solution and secondary raffinate merged to concentrated, the dry Radix Dichroae dry powder that obtains;
(5), get after all the other Chinese medicine coarse powder except Radix Dichroae mix and again pulverize, cross 100 mesh sieves, obtain raw material of Chinese medicine fine powder;
(6), get the raw material of Chinese medicine fine powder mix homogeneously obtaining in Radix Dichroae dry powder that step (4) makes and step (5), pulverize and cross 100 mesh sieves, then carry out micronizing, after 325 mesh sieves, obtain Chinese medicine composition.
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| CN104666788A (en) * | 2013-11-26 | 2015-06-03 | 天津嘉瑞生物科技有限公司 | Traditional Chinese medicine decoction for preventing and treating chicken coccocidiosis and preparation method thereof |
| CN109588571A (en) * | 2018-12-28 | 2019-04-09 | 红河县沣圃园养殖有限责任公司 | Utilize the method for Chinese herbal medicine raising chicken |
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| CN101961066A (en) * | 2009-07-22 | 2011-02-02 | 吉林农业大学 | Anti-chicken coccidiosis feed additive |
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