CN106511873A - Traditional Chinese medicine feed additive and preparing method thereof - Google Patents
Traditional Chinese medicine feed additive and preparing method thereof Download PDFInfo
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- CN106511873A CN106511873A CN201610917565.5A CN201610917565A CN106511873A CN 106511873 A CN106511873 A CN 106511873A CN 201610917565 A CN201610917565 A CN 201610917565A CN 106511873 A CN106511873 A CN 106511873A
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- A—HUMAN NECESSITIES
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9064—Amomum, e.g. round cardamom
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- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/32—Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
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- A61K35/56—Materials from animals other than mammals
- A61K35/58—Reptiles
- A61K35/586—Turtles; Tortoises, e.g. terrapins
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- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/076—Poria
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Abstract
The invention belongs to the technical field of feed additive research and development and particularly relates to a traditional Chinese medicine feed additive and a preparing method thereof. The traditional Chinese medicine feed additive is prepared from, by weight, 7-28 parts of honeysuckle flower, 8-15 parts of Radix et Rhizoma Rhei, 15-30 parts of Rhizoma Curculiginis, 8-15 parts of rhizoma coptidis, 6-12 parts of liquorice root, 6-15 parts of eucommia barks, 10-20 parts of rhizoma alismatis, 10-30 parts of poria cocos, 15-30 parts of medicine terminalia fruits, 9-15 parts of dwarf lilyturf roots, 7-14 parts of herba epimedii, 8-20 parts of acanthopanax root, 15-35 parts of velvet antler, 10-30 parts of semen cuscutae, 15-23 parts of fructus evodiae, 9-18 parts of tortoise-plastron glue, 9-18 parts of herba cistanches, 20-35 parts of radix ophiopogonis, 6-20 parts of Rhizoma Atractylodis Macrocephalae, 3-6 parts of radix aconiti lateralis preparata, 10-26 parts of herba houttuyniae, 8-16 parts of fructus amomi and 9-20 parts of fructus rubi. The traditional Chinese medicine feed additive has the effects of astringing, detoxifying, spleen strengthening, kidney nourishing and digestion promoting; grass carps can be protected against diseases; the survival rate of the grass carps is increased, and activity of lysozyme and superoxide dismutase in grass carp bodies are improved.
Description
Technical field
The invention belongs to feed additive research and development technology field, more particularly to a kind of Chinese medicine feeding for improving Ctenopharyngodon idellus resistances against diseases
Feed additives and preparation method thereof.
Background technology
In recent years, Ctenopharyngodon idellus were one of four large Chinese carps of China, and the Freshwater Fish that China is main, and Ctenopharyngodon idellus cultivation is with feedstuff
The advantages of low cost, obvious economic benefit, and because piercing liking for less and extremely consumer between its fine and tender taste, individual big, flesh,
Develop into the govern-house-variety of China's freshwater aquiculture.But the erythroderma that is easily subject in breeding process due to Ctenopharyngodon idellus, gill rot,
Enteritis disease and hemorrhagic disease are referred to as the infringement of " Ctenopharyngodon idellus four are sick ", and fish production is made a big impact.In order to solve Ctenopharyngodon idellus " four
The immune function prevented and treated problem, need raising Ctenopharyngodon idellus conscientiously of disease ".
Chinese herbal medicine is a kind of preferably natural, environment-friendly medicine, little, safe, residual with efficient, toxic and side effects
Many advantages, such as staying few, and wide material sources, low cost.The immunity of aquatic animal is improved by the administration of Chinese herbal medicine, improves dynamic
Thing premunition, the sickness rate for reducing aquatic animal is the focus studied in recent years.In the new shape for advocating healthy aquaculture at present comprehensively
Under gesture, herbal control fish diseasess are promoted, is extremely important.
The present invention is exactly on this basis, to propose a kind of Chinese medicine feed additive for improving Ctenopharyngodon idellus resistances against diseases, its
With efficiently, have no toxic side effect, safe, noresidue many advantages, such as, and wide material sources, low cost, the immunity to Fish
System is adjusted, and improves the dynamic resistances against diseases of Aquatic product and immune function, so as to preventing and curing of fish disease.
The information for being disclosed in the background section is merely intended to increase the understanding of the general background to the present invention, and should not
When the prior art for being considered to recognize or imply the information structure in any form well known to persons skilled in the art.
The content of the invention
For above-mentioned deficiency present in prior art, the present invention provides a kind of Chinese medicine feed additive and its preparation side
Method, the Chinese medicine feed additive reasonable recipe, prepare simple, effect substantially, have no toxic side effect, have no drug resistance and drug residue,
Ctenopharyngodon idellus resistances against diseases can be effectively improved.
To achieve these goals, the present invention is to employ the following technical solutions realization：
A kind of Chinese medicine feed additive, by being made up of following components by weight：Flos Lonicerae 7-28 parts, Radix Et Rhizoma Rhei 8-15 parts,
Rhizoma Curculiginises 15-30 parts, Rhizoma Coptidis 8-15 parts, Radix Glycyrrhizae 6-12 parts, Cortex Eucommiae 6-15 part, Rhizoma Alismatis 10-20 parts, Poria 10-30 parts, Fructus Chebulae 15-
30 parts, Radix Ophiopogonis 9-15 parts, Herba Epimedii 7-14 parts, Radix Et Caulis Acanthopanacis Senticosi 8-20 parts, Cornu Cervi Pantotrichum 15-35 parts, Semen Cuscutae 10-30 parts, Fructus Evodiae
15-23 parts, Colla Plastri Testudiniss 9-18 parts, Herba Cistanches 9-18 parts, 20-35 parts Radix Ophiopogonis, what art 6-20 part, Radix Aconiti Lateralis Preparata 3-6 parts, Herba Houttuyniae
10-26 parts, Fructus Amomi 8-16 parts and Fructus Rubi 9-20 parts.
Preferably, described Chinese medicine feed additive, by being made up of following components by weight：It is 25 parts of Flos Lonicerae, big
Yellow 10 parts, 20 parts of Rhizoma Curculiginises, 11 parts of Rhizoma Coptidis, 10 parts of Radix Glycyrrhizae, 12 parts of the Cortex Eucommiae, 15 parts of Rhizoma Alismatis, 20 parts of Poria, 21 parts of Fructus Chebulae, Radix Ophiopogonis
12 parts, 10 parts of Herba Epimedii, 12 parts of Radix Et Caulis Acanthopanacis Senticosi, 30 parts of Cornu Cervi Pantotrichum, 20 parts of Semen Cuscutae, 20 parts of Fructus Evodiae, 13 parts of Colla Plastri Testudiniss, Herba Cistanches 13
15 parts of part, 30 parts of Radix Ophiopogonis, 10 parts of what art, 5 parts of Radix Aconiti Lateralis Preparata, 20 parts of Herba Houttuyniae, 12 parts of Fructus Amomi and Fructus Rubi.
In addition, present invention also offers the preparation method of described Chinese medicine feed additive, comprises the following steps：
(1) Flos Lonicerae in formula, Radix Et Rhizoma Rhei is weighed by weight, Rhizoma Curculiginises, Rhizoma Coptidis, Radix Glycyrrhizae, the Cortex Eucommiae, Rhizoma Alismatis, Poria, scolded
Son, Radix Ophiopogonis, Herba Epimedii, Radix Et Caulis Acanthopanacis Senticosi, Cornu Cervi Pantotrichum, Semen Cuscutae, Fructus Evodiae, Colla Plastri Testudiniss, Herba Cistanches, Radix Ophiopogonis, what art, Radix Aconiti Lateralis Preparata, fish
Raw meat grass, Fructus Amomi, Fructus Rubi, Cornu Cervi Pantotrichum, Colla Plastri Testudiniss this two tastes are first crushed and shelve standby, and remaining is cleaned and dries, except Fructus Evodiae, fish raw meat
Outside grass, Fructus Amomi, the tap water of its 3-4 times of weight after being pulverized and mixed by pulverizer, is added, slow fire again is first boiled by intense fire and is endured 0.5-
1h, after filtration first filtrate, add the tap water of its weight 2-3 times toward medicinal residues, boil rear slow fire by intense fire and endure 0.5h and add
Fructus Evodiae, Herba Houttuyniae, Fructus Amomi are continuous to endure 5-10min, pours out second filtrate, is concentrated to give herb liquid study after merging filtrate twice；
(2) in the herb liquid study obtained by step (1), add the dehydrated alcohol of its volume 2-6 times, stirring and dissolving to dilute,
Flow back at a temperature of 85-95 DEG C 2.5-3.5h, obtains refined herb liquid；
(3) the refined herb liquid obtained by step (2) is taken, after decompression recycling ethanol, by herb liquid low-temperature evaporation, latex shape is obtained
Middle medicinal substances, glue milky substance are put in drying machine and are dried, and inlet temperature is 140-160 DEG C, and leaving air temp is 75-90 DEG C,
Powdered rubber is obtained, step (1) is then added and is shelved standby Cornu Cervi Pantotrichum, Colla Plastri Testudiniss powder, mixed, be crushed to 120 mesh, stirred
Uniformly, obtain Chinese medicinal powder；
(4) Chinese medicinal powder obtained by step (3) is admixed the parching to brown Semen Glycines powder of its quality 2-3 times, is mixed, carry out expanded, temperature
At 85-90 DEG C, expanded time 1-2min, subsequent pelletize, cooling treat that particulate component is cooled to 20-25 DEG C, pack, i.e., for degree control
Obtain Chinese medicine feed additive.
Compared with prior art, the present invention has the advantages that：
(1) Chinese medicine feed additive of the invention has functions that kidney, digestion promoting are supported in convergence removing toxic substances, spleen invigorating, is prevented from
Ctenopharyngodon idellus are ill, improve Ctenopharyngodon idellus survival rate, improve the vigor of lysozyme and superoxide dismutase in Ctenopharyngodon idellus body.
(2) Chinese medicine feed additive raw material of the invention is pure natural raw material, without any chemical classes medicine, preparation side
Method is simple, and the Chinese medicine feed additive residual rate is low, toxicity is low, does not affect the quality of Ctenopharyngodon idellus, is not detrimental to health.
(3) Chinese medicine feed additive preparation method of the invention is simple, it is easy to large-scale promotion and application.
Specific embodiment
The specific embodiment of the present invention is described in detail with reference to specific embodiment, it is to be understood that of the invention
Protection domain do not limited by specific embodiment.
Embodiment 1：
A kind of Chinese medicine feed additive, by being made up of following components by weight：7 parts of Flos Lonicerae, 8 parts of Radix Et Rhizoma Rhei, Rhizoma Curculiginises 15
Part, 8 parts of Rhizoma Coptidis, 6 parts of Radix Glycyrrhizae, 6 parts of the Cortex Eucommiae, 10 parts of Rhizoma Alismatis, 10 parts of Poria, 15 parts of Fructus Chebulae, 9 parts of Radix Ophiopogonis, 7 parts of Herba Epimedii, thorn
8 parts of slender acanthopanax, 15 parts of Cornu Cervi Pantotrichum, 10 parts of Semen Cuscutae, 15 parts of Fructus Evodiae, 9 parts of Colla Plastri Testudiniss, 9 parts of Herba Cistanches, 20 parts of Radix Ophiopogonis, 6 parts of what art,
9 parts of 3 parts of Radix Aconiti Lateralis Preparata, 10 parts of Herba Houttuyniae, 8 parts of Fructus Amomi and Fructus Rubi.
The preparation method of described Chinese medicine feed additive, comprises the following steps：
(1) Flos Lonicerae in formula, Radix Et Rhizoma Rhei is weighed by weight, Rhizoma Curculiginises, Rhizoma Coptidis, Radix Glycyrrhizae, the Cortex Eucommiae, Rhizoma Alismatis, Poria, scolded
Son, Radix Ophiopogonis, Herba Epimedii, Radix Et Caulis Acanthopanacis Senticosi, Cornu Cervi Pantotrichum, Semen Cuscutae, Fructus Evodiae, Colla Plastri Testudiniss, Herba Cistanches, Radix Ophiopogonis, what art, Radix Aconiti Lateralis Preparata, fish
Raw meat grass, Fructus Amomi, Fructus Rubi, Cornu Cervi Pantotrichum, Colla Plastri Testudiniss this two tastes are first crushed and shelve standby, and remaining is cleaned and dries, except Fructus Evodiae, fish raw meat
Outside grass, Fructus Amomi, the tap water of its 3 times of weight after being pulverized and mixed by pulverizer, is added, slow fire again is first boiled by intense fire and is endured 0.5h,
After filtration first filtrate, add the tap water of 2 times of its weight toward medicinal residues, boil rear slow fire by intense fire and endure 0.5h and add Wu Zhu
Cornel, Herba Houttuyniae, Fructus Amomi are continuous to endure 5min, pours out second filtrate, is concentrated to give herb liquid study after merging filtrate twice；
(2) in the herb liquid study obtained by step (1), add the dehydrated alcohol of 2 times of its volume, stirring and dissolving to dilute,
Flow back at a temperature of 85 DEG C 2.5h, obtains refined herb liquid；
(3) the refined herb liquid obtained by step (2) is taken, after decompression recycling ethanol, by herb liquid low-temperature evaporation, latex shape is obtained
Middle medicinal substances, glue milky substance are put in drying machine and are dried, and inlet temperature is 140 DEG C, and leaving air temp is 75 DEG C, obtains powder
Material, then adds step (1) and shelves standby Cornu Cervi Pantotrichum, Colla Plastri Testudiniss powder, mixing, is crushed to 120 mesh, stirs, obtains
Chinese medicinal powder；
(4) Chinese medicinal powder obtained by step (3) is admixed the parching to brown Semen Glycines powder of 2 times of its quality, is mixed, is carried out expanded, temperature
At 85 DEG C, expanded time 1min, subsequent pelletize, cooling treat that particulate component is cooled to 20 DEG C, pack, obtain final product Chinese medicine fodder for control
Additive.
Embodiment 2：
A kind of Chinese medicine feed additive, by being made up of following components by weight：28 parts of Flos Lonicerae, 15 parts of Radix Et Rhizoma Rhei, Rhizoma Curculiginises
30 parts, 15 parts of Rhizoma Coptidis, 12 parts of Radix Glycyrrhizae, 15 parts of the Cortex Eucommiae, 20 parts of Rhizoma Alismatis, 30 parts of Poria, 30 parts of Fructus Chebulae, 15 parts of Radix Ophiopogonis, Herba Epimedii
14 parts, 20 parts of Radix Et Caulis Acanthopanacis Senticosi, 35 parts of Cornu Cervi Pantotrichum, 30 parts of Semen Cuscutae, 23 parts of Fructus Evodiae, 18 parts of Colla Plastri Testudiniss, 18 parts of Herba Cistanches, Radix Ophiopogonis 35
Part, 20 parts of what art, 6 parts of Radix Aconiti Lateralis Preparata, 26 parts of Herba Houttuyniae, 16 parts of Fructus Amomi and 20 parts of Fructus Rubi.
The preparation method of described Chinese medicine feed additive, comprises the following steps：
(1) Flos Lonicerae in formula, Radix Et Rhizoma Rhei is weighed by weight, Rhizoma Curculiginises, Rhizoma Coptidis, Radix Glycyrrhizae, the Cortex Eucommiae, Rhizoma Alismatis, Poria, scolded
Son, Radix Ophiopogonis, Herba Epimedii, Radix Et Caulis Acanthopanacis Senticosi, Cornu Cervi Pantotrichum, Semen Cuscutae, Fructus Evodiae, Colla Plastri Testudiniss, Herba Cistanches, Radix Ophiopogonis, what art, Radix Aconiti Lateralis Preparata, fish
Raw meat grass, Fructus Amomi, Fructus Rubi, Cornu Cervi Pantotrichum, Colla Plastri Testudiniss this two tastes are first crushed and shelve standby, and remaining is cleaned and dries, except Fructus Evodiae, fish raw meat
Outside grass, Fructus Amomi, the tap water of its 4 times of weight after being pulverized and mixed by pulverizer, is added, slow fire again is first boiled by intense fire and is endured 1h, mistake
After filter first filtrate, add the tap water of 3 times of its weight toward medicinal residues, boil by intense fire rear slow fire endure 0.5h add Fructus Evodiae,
Herba Houttuyniae, Fructus Amomi are continuous to endure 10min, pours out second filtrate, is concentrated to give herb liquid study after merging filtrate twice；
(2) in the herb liquid study obtained by step (1), add the dehydrated alcohol of 6 times of its volume, stirring and dissolving to dilute,
Flow back at a temperature of 95 DEG C 3.5h, obtains refined herb liquid；
(3) the refined herb liquid obtained by step (2) is taken, after decompression recycling ethanol, by herb liquid low-temperature evaporation, latex shape is obtained
Middle medicinal substances, glue milky substance are put in drying machine and are dried, and inlet temperature is 160 DEG C, and leaving air temp is 90 DEG C, obtains powder
Material, then adds step (1) and shelves standby Cornu Cervi Pantotrichum, Colla Plastri Testudiniss powder, mixing, is crushed to 120 mesh, stirs, obtains
Chinese medicinal powder；
(4) Chinese medicinal powder obtained by step (3) is admixed the parching to brown Semen Glycines powder of 3 times of its quality, is mixed, is carried out expanded, temperature
At 90 DEG C, expanded time 2min, subsequent pelletize, cooling treat that particulate component is cooled to 25 DEG C, pack, obtain final product Chinese medicine fodder for control
Additive.
Embodiment 3：
A kind of Chinese medicine feed additive, by being made up of following components by weight：15 parts of Flos Lonicerae, 10 parts of Radix Et Rhizoma Rhei, Rhizoma Curculiginises
20 parts, 12 parts of Rhizoma Coptidis, 10 parts of Radix Glycyrrhizae, 9 parts of the Cortex Eucommiae, 15 parts of Rhizoma Alismatis, 20 parts of Poria, 20 parts of Fructus Chebulae, 12 parts of Radix Ophiopogonis, Herba Epimedii 10
Part, 15 parts of Radix Et Caulis Acanthopanacis Senticosi, 25 parts of Cornu Cervi Pantotrichum, 20 parts of Semen Cuscutae, 20 parts of Fructus Evodiae, 13 parts of Colla Plastri Testudiniss, 12 parts of Herba Cistanches, 30 parts of Radix Ophiopogonis,
15 parts of 10 parts of what art, 5 parts of Radix Aconiti Lateralis Preparata, 20 parts of Herba Houttuyniae, 12 parts of Fructus Amomi and Fructus Rubi.
The preparation method of described Chinese medicine feed additive, comprises the following steps：
(1) Flos Lonicerae in formula, Radix Et Rhizoma Rhei is weighed by weight, Rhizoma Curculiginises, Rhizoma Coptidis, Radix Glycyrrhizae, the Cortex Eucommiae, Rhizoma Alismatis, Poria, scolded
Son, Radix Ophiopogonis, Herba Epimedii, Radix Et Caulis Acanthopanacis Senticosi, Cornu Cervi Pantotrichum, Semen Cuscutae, Fructus Evodiae, Colla Plastri Testudiniss, Herba Cistanches, Radix Ophiopogonis, what art, Radix Aconiti Lateralis Preparata, fish
Raw meat grass, Fructus Amomi, Fructus Rubi, Cornu Cervi Pantotrichum, Colla Plastri Testudiniss this two tastes are first crushed and shelve standby, and remaining is cleaned and dries, except Fructus Evodiae, fish raw meat
Outside grass, Fructus Amomi, the tap water of its 3.5 times of weight after being pulverized and mixed by pulverizer, is added, slow fire again is first boiled by intense fire and is endured
0.8h, after filtration first filtrate, add the tap water of 2.5 times of its weight toward medicinal residues, boil rear slow fire by intense fire and endure 0.5h and add again
Enter that Fructus Evodiae, Herba Houttuyniae, Fructus Amomi are continuous to endure 8min, pour out second filtrate, after merging filtrate twice, be concentrated to give herb liquid study；
(2) in the herb liquid study obtained by step (1), add the dehydrated alcohol of 4 times of its volume, stirring and dissolving to dilute,
Flow back at a temperature of 90 DEG C 3.0h, obtains refined herb liquid；
(3) the refined herb liquid obtained by step (2) is taken, after decompression recycling ethanol, by herb liquid low-temperature evaporation, latex shape is obtained
Middle medicinal substances, glue milky substance are put in drying machine and are dried, and inlet temperature is 150 DEG C, and leaving air temp is 80 DEG C, obtains powder
Material, then adds step (1) and shelves standby Cornu Cervi Pantotrichum, Colla Plastri Testudiniss powder, mixing, is crushed to 120 mesh, stirs, obtains
Chinese medicinal powder；
(4) Chinese medicinal powder obtained by step (3) is admixed the parching to brown Semen Glycines powder of 2.5 times of its quality, is mixed, carry out expanded, temperature
At 88 DEG C, expanded time 1.5min, subsequent pelletize, cooling treat that particulate component is cooled to 23 DEG C, pack, obtain final product Chinese medicine for degree control
Feed additive.
Embodiment 4：The Chinese medicine feed additive of the present invention is tested to survival rate and resistances against diseases
Experimental animal：Test Ctenopharyngodon idellus are purchased from Nanning City fish farm, are juvenile fish, body weight 80-86g/ tail, selected test fry
Number is 4000 tails, and healthy strong, male and female have.4000 tail Ctenopharyngodon idellus are randomly divided into into four groups：Test group 1-3 and matched group, per group
Containing 1000 tail of juvenile fish.
Test feed：Chinese medicine feed additive mixed fodder prepared by test group 1-3 difference feeding embodiment of the present invention 1-3
(will 150g above-described embodiment 1-3 Chinese medicine feed additives, 80g soybean cakes, 350g wheat flours, 35g crab shell powders, 60g shrimp meals, 10g
Sal, 160g Semen Maydis powder, 30g fish oil, 15g glycine betaines, 2g dalcium biphosphates, 2g ferric citrates, 40g compound vitamin Bs, 30g
Yeast, 20g threonine, 20g lysines, mix homogeneously)；The feedstuff of matched group feeding with the difference of test group is：Using Huang
Mycin 20mg/kg replaces the Chinese medicine feed additive that the present invention is used.
Feeding method：Date of test is 8 days-October 22 May in 2015.Ctenopharyngodon idellus are cultivated in fish pond, stocking density 1
Bar/20L.Fish pond area 1500m2(long 50m × wide 30m), deep 80cm, with bamboo fence, (water can pass through, and fish can not be by being mark
It is accurate) separate and block into 375m24 blockages；Fish pond coolant-temperature gage it is whole it is average 16 DEG C (wherein 24-29 DEG C of summer, average 25.5
DEG C), pH value 6.5 ± 0.2, water quality meet fishery standard.
Feedstuff day feeding volume by fry weight 3-5% it is quantitative it is of fixed place and time feed, feed 2 times/d, every 10d dosages 1 time.Adjust
Look into the survival rate of Ctenopharyngodon idellus.
Fish is put to death, with buffer (pH value 7.5,0.25mol/ sucrose, 0.025mol/L Tris-HCL, 0.1mmol/L
EDTA-2Na solution) rinse, then surface moisture is sucked with absorbent paper, remove bone parts, leave the groups such as heart, liver and gonad
Knit homogenate.Tissue 0.30g is accurately weighed, 9 times of buffer ice bath homogenate, 3000r/min low-temperature and high-speed centrifuges is added
10-15min, takes supernatant 2mL and determines lysozyme and superoxide dismutase vigor.
Test data represents that using means standard deviation (x ± s) two sample averages compare to be checked with t, and two samples constitute ratio
With chi-square criterion, P<0.05 has significance for difference.
As a result：Impact of the Chinese medicine feed additive to Ctenopharyngodon idellus survival rate, is shown in Table 1；Chinese medicine feed additive to lysozyme and
The impact of superoxide dismutase vigor, the results are shown in Table 2.
Impact of the Chinese medicine feed additive of 1 present invention of table to Ctenopharyngodon idellus survival rate
As it can be seen from table 1 the feedstuff feeding Ctenopharyngodon idellus prepared using the present invention, its ill probability reduction, survival rate
It is significantly higher than matched group.
Impact of the Chinese medicine feed additive of 2 present invention of table to lysozyme and superoxide dismutase vigor
| Group | Lysozyme (U mL-1) | Superoxide dismutase (U mL-1) |
| Test group 1 | 475±14.12 | 188±10.15 |
| Test group 2 | 488±11.47 | 180±11.91 |
| Test group 3 | 486±11.21 | 183±11.74 |
| Matched group | 361±10.02 | 121±2.01 |
From table 2 it can be seen that using lysozyme and super oxygen in the Ctenopharyngodon idellus body of the Chinese medicine feed additive feeding of the present invention
Thing dismutase levels are significantly improved, and so as to prove which has preferably defence disease, antiviral and antibacterial ability, immune level is more
It is high.
It is aforementioned to the present invention specific illustrative embodiment description be in order to illustrate and illustration purpose.These descriptions
It is not wishing to limit the invention to disclosed precise forms, and it will be apparent that according to above-mentioned teaching, much can be changed
And change.The purpose of selecting and describing the exemplary embodiment is that explaining that the certain principles and its reality of the present invention should
With so that those skilled in the art can realize and using the present invention a variety of exemplaries and
A variety of selections and change.The scope of the present invention is intended to be limited by claims and its equivalents.
Claims (3)
1. a kind of Chinese medicine feed additive, it is characterised in that by being made up of following components by weight：It is Flos Lonicerae 7-28 parts, big
Yellow 8-15 parts, Rhizoma Curculiginises 15-30 parts, Rhizoma Coptidis 8-15 parts, Radix Glycyrrhizae 6-12 parts, Cortex Eucommiae 6-15 part, Rhizoma Alismatis 10-20 parts, Poria 10-30
Part, Fructus Chebulae's 15-30 parts, Radix Ophiopogonis 9-15 parts, Herba Epimedii 7-14 parts, Radix Et Caulis Acanthopanacis Senticosi 8-20 parts, Cornu Cervi Pantotrichum 15-35 parts, Semen Cuscutae 10-30
Part, Fructus Evodiae 15-23 parts, Colla Plastri Testudiniss 9-18 parts, Herba Cistanches 9-18 parts, 20-35 parts Radix Ophiopogonis, what art 6-20 part, Radix Aconiti Lateralis Preparata 3-6
Part, Herba Houttuyniae 10-26 parts, Fructus Amomi 8-16 parts and Fructus Rubi 9-20 parts.
2. Chinese medicine feed additive according to claim 1, it is characterised in that by being made up of following components by weight：
25 parts of Flos Lonicerae, 10 parts of Radix Et Rhizoma Rhei, 20 parts of Rhizoma Curculiginises, 11 parts of Rhizoma Coptidis, 10 parts of Radix Glycyrrhizae, 12 parts of the Cortex Eucommiae, 15 parts of Rhizoma Alismatis, 20 parts of Poria, scold
21 parts of son, 12 parts of Radix Ophiopogonis, 10 parts of Herba Epimedii, 12 parts of Radix Et Caulis Acanthopanacis Senticosi, 30 parts of Cornu Cervi Pantotrichum, 20 parts of Semen Cuscutae, 20 parts of Fructus Evodiae, Colla Plastri Testudiniss
15 parts of 13 parts, 13 parts of Herba Cistanches, 30 parts of Radix Ophiopogonis, 10 parts of what art, 5 parts of Radix Aconiti Lateralis Preparata, 20 parts of Herba Houttuyniae, 12 parts of Fructus Amomi and Fructus Rubi.
3. the preparation method of Chinese medicine feed additive according to claim 1 and 2, it is characterised in that comprise the following steps：
(1) weigh by weight Flos Lonicerae in formula, Radix Et Rhizoma Rhei, Rhizoma Curculiginises, Rhizoma Coptidis, Radix Glycyrrhizae, the Cortex Eucommiae, Rhizoma Alismatis, Poria, Fructus Chebulae,
Radix Ophiopogonis, Herba Epimedii, Radix Et Caulis Acanthopanacis Senticosi, Cornu Cervi Pantotrichum, Semen Cuscutae, Fructus Evodiae, Colla Plastri Testudiniss, Herba Cistanches, Radix Ophiopogonis, what art, Radix Aconiti Lateralis Preparata, fish raw meat
Grass, Fructus Amomi, Fructus Rubi, Cornu Cervi Pantotrichum, Colla Plastri Testudiniss this two tastes are first crushed and shelve standby, and remaining is cleaned and dries, except Fructus Evodiae, Herba Houttuyniae,
The tap water of its 3-4 times of weight outside Fructus Amomi, after being pulverized and mixed by pulverizer, is added, slow fire again is first boiled by intense fire and is endured 0.5-1h,
After filtration first filtrate, add the tap water of its weight 2-3 times toward medicinal residues, boil rear slow fire by intense fire and endure 0.5h and add Wu Zhu
Cornel, Herba Houttuyniae, Fructus Amomi are continuous to endure 5-10min, pours out second filtrate, is concentrated to give herb liquid study after merging filtrate twice；
(2) in the herb liquid study obtained by step (1), add the dehydrated alcohol of its volume 2-6 times, stirring and dissolving to dilute,
Flow back at a temperature of 85-95 DEG C 2.5-3.5h, obtains refined herb liquid；
(3) the refined herb liquid obtained by step (2) is taken, after decompression recycling ethanol, by herb liquid low-temperature evaporation, latex shape Chinese medicine is obtained
Material, glue milky substance is put in drying machine and is dried, and inlet temperature is 140-160 DEG C, and leaving air temp is 75-90 DEG C, is obtained
Powdered rubber, then adds step (1) and shelves standby Cornu Cervi Pantotrichum, Colla Plastri Testudiniss powder, mixing, is crushed to 120 mesh, and stirring is equal
It is even, obtain Chinese medicinal powder；
(4) Chinese medicinal powder obtained by step (3) is admixed the parching to brown Semen Glycines powder of its quality 2-3 times, is mixed, is carried out expanded, temperature control
At 85-90 DEG C, expanded time 1-2min, subsequent pelletize, cooling treat that particulate component is cooled to 20-25 DEG C to system, pack, in obtaining final product
Medicine feed additive.
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Application publication date: 20170322 |