CN106387514A - Traditional Chinese medicine feed additive for fish and preparation method thereof - Google Patents

Traditional Chinese medicine feed additive for fish and preparation method thereof Download PDF

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Publication number
CN106387514A
CN106387514A CN201611032264.0A CN201611032264A CN106387514A CN 106387514 A CN106387514 A CN 106387514A CN 201611032264 A CN201611032264 A CN 201611032264A CN 106387514 A CN106387514 A CN 106387514A
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parts
chinese medicine
feed additive
fish
radix
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CN201611032264.0A
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何祥英
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Fangchenggang Municipal Bureau Of Oceanography
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Fangchenggang Municipal Bureau Of Oceanography
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    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/80Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in fisheries management
    • Y02A40/81Aquaculture, e.g. of fish
    • Y02A40/818Alternative feeds for fish, e.g. in aquacultures

Abstract

The invention belongs to the technical field of research and development of a feed additive and especially relates to a traditional Chinese medicine feed additive for fish and a preparation method thereof. The traditional Chinese medicine feed additive for fish comprises the following components in parts by weight: 10-30 parts of angelica sinensis, 8-16 parts of polygonum multiflorum, 9-18 parts of nutmeg, 7-21 parts of chrysanthemum, 15-30 parts of ephedra, 8-15 parts of notopterygium roots, 25-35 parts of radix bupleuri, 10-25 parts of immature citron fruits and 6-15 parts of olibanum. The traditional Chinese medicine components in the traditional Chinese medicine feed additive for fish have synergic effects. The prepared traditional Chinese medicine feed additive can prevent grass carps from falling ill, can increase the survival rate of the grass carps and can improve the activity level of lysozyme, superoxide dismutase, catalase and alkaline phosphatase in the body of the grass carps.

Description

A kind of Fish Chinese medicine feed additive and preparation method thereof
Technical field
The invention belongs to feed additive research and development technology field, particularly to a kind of Fish Chinese medicine feed additive and its system Preparation Method.
Background technology
Ctenopharyngodon idellus are one of China four large Chinese carps, are also the main Freshwater Fish of China, Ctenopharyngodon idellus cultivation have feed cost low, The advantages of economic benefit is obvious.But the erythroderma being easily subject in breeding process due to Ctenopharyngodon idellus, gill rot, enteritis disease and bleeding Disease is referred to as the infringement of " Ctenopharyngodon idellus four disease ", and fish production is made a big impact.Prevent and treat problem in order to solve Ctenopharyngodon idellus " four disease ", Need conscientiously to improve the immune function of Ctenopharyngodon idellus.
Chinese herbal medicine is that one kind is preferably natural, environment-friendly medicine, have efficiently, toxic and side effects little, safe, residual Many advantages, such as stay few, and wide material sources, low cost.Improve the immunity of aquatic animal by the administration of Chinese herbal medicine, improve fish Class premunition, the sickness rate reducing aquatic animal is the focus studied in recent years.At present comprehensively advocate healthy aquaculture new shape Under gesture, improve fish immunity function using Chinese herbal medicine, be extremely important.
Application No. 201310630290.3《For improving the immune formulation of Ctenopharyngodon idellus immune function》Patent of invention public Opened a kind of immune formulation for improving Ctenopharyngodon idellus immune function it is characterised in that:Crude drug is by Polyporus, Radix Et Caulis Acanthopanacis Senticosi, the Rhizoma Atractylodis Macrocephalae, people Rhizoma panacis majoris, Herba Houttuyniae, the Cortex Eucommiae, Herba Ecliptae, Rhizoma Drynariae, Ramulus Cinnamomi, Radix Isatidis, Fructus Crataegi, Endothelium Corneum Gigeriae Galli, Flos Campsiss, Rhizoma Dioscoreae, Caulis Spatholobi, soap Fructus Gleditsia acupuncture, Fructus Corni, Ramulus Persicae, Fructus Cnidii, Fructus Jujubae, the Radix Stemonae, Semen Euryaless, Fructus Galangae, Semen Arecae, pittosporm root and Conyza canadensis (L.) Cronq. are constituted.From entirety See, this formula biases toward spleen reinforcing and supports kidney, adjusts gastrointestinal function, and for enteritis disease effect still, but this patent is not given enough Data illustrates that this kind of immune formulation has ideal effect for the preventing and treating of Ctenopharyngodon idellus viral disease, bacterial disease.
In view of the defect of prior art, a kind of Chinese medicine fodder interpolation for improving Ctenopharyngodon idellus immune function of present invention proposition Agent, its have efficiently, have no toxic side effect, safe, noresidue many advantages, such as, and wide material sources, low cost, to Fish Immune system carries out across-the-board regulation, improves resistances against diseases and the immune function that Aquatic product moves, thus preventing and curing of fish disease.
The information being disclosed in this background section is merely intended to increase the understanding of the general background to the present invention, and should not Recognize when being considered or imply in any form that this information structure has been the prior art well known to persons skilled in the art.
Content of the invention
For deficiency above-mentioned present in prior art, the present invention provides a kind of Fish Chinese medicine feed additive and its preparation Method, this Chinese medicine feed additive reasonable recipe, preparation are simply, effect is obvious, have no toxic side effect, have no drug resistance and medicine is residual Stay, Ctenopharyngodon idellus immune function can be effectively improved.
To achieve these goals, the present invention is to employ the following technical solutions realization:
A kind of Fish Chinese medicine feed additive, by being made up of following components by weight:Radix Angelicae Sinensis 10-30 part, Radix Polygoni Multiflori 8- 16 parts, Semen Myristicae 9-18 part, Flos Chrysanthemi 7-21 part, Herba Ephedrae 15-30 part, Rhizoma Et Radix Notopterygii 8-15 part, Radix Bupleuri 25-35 part, Fructus Aurantii Immaturus 10-25 part and Olibanum 6-15 part.
Preferably, described Fish Chinese medicine feed additive, by being made up of following components by weight:20 parts of Radix Angelicae Sinensis, 12 parts of Radix Polygoni Multiflori, 15 parts of Semen Myristicae, 12 parts of Flos Chrysanthemi, 25 parts of Herba Ephedrae, 11 parts of Rhizoma Et Radix Notopterygii, 30 parts of Radix Bupleuri, 20 parts of Fructus Aurantii Immaturus and 10 parts of Olibanum.
In addition, present invention also offers the preparation method of described Fish Chinese medicine feed additive, comprising the following steps:
(1) weigh by weight Radix Angelicae Sinensis in formula, Radix Polygoni Multiflori, Semen Myristicae, Flos Chrysanthemi, Herba Ephedrae, Rhizoma Et Radix Notopterygii, Radix Bupleuri, Fructus Aurantii Immaturus, Olibanum, is cleaned and dries, after being pulverized and mixed by pulverizer, add the tap water of its 3-4 times of weight, first boil slow fire again by intense fire and endure 0.5-1h, obtains first filtrate, adds the tap water of its weight 2-3 times toward medicinal residues, boil rear slow fire by intense fire and endure 0.5h, after filtration Go out second filtrate, merge and be concentrated to give herb liquid study after filtrate twice;
(2) add the dehydrated alcohol of its volume 3-5 times in the herb liquid study of step (1) gained, stirring and dissolving dilutes, Flow back at a temperature of 85-95 DEG C 2.5-3.5h, obtains refined herb liquid;
(3) take the refined herb liquid of step (2) gained, after decompression recycling ethanol, by herb liquid low-temperature evaporation, obtain latex shape Middle medicinal substances, glue milky substance are put in drying machine and are dried, and inlet temperature is 130-150 DEG C, and leaving air temp is 75-90 DEG C, Obtain powdered rubber, powdered rubber is crushed to 120 mesh, obtains Chinese medicinal powder;
(4) Chinese medicinal powder of step (3) gained is admixed the Semen Maydis powder of its quality 2-3 times, mix, carry out expanded, temperature Control at 85-90 DEG C, expanded time 1-2min, subsequent pelletize, cooling, treat that particulate component is cooled to 20-25 DEG C, packaging, obtain final product Fish Chinese medicine feed additive.
Compared with prior art, the present invention has the advantages that:
(1) there is synergistic function, in preparing between each Chinese medicine ingredients of Fish Chinese medicine feed additive of the present invention Medicine feed additive has functions that kidney, digestion promoting are supported in convergence removing toxic substances, spleen invigorating, the immune system of Fish is adjusted, improves The anti-stress ability of Ctenopharyngodon idellus and immune function, are prevented from Ctenopharyngodon idellus illness, improve Ctenopharyngodon idellus survival rate, improve bacteriolyze in Ctenopharyngodon idellus body Enzyme, superoxide dismutase, catalase, the activity level of alkali phosphatase.
(2) the Fish Chinese medicine feed additive raw material of the present invention is pure natural raw material, without any chemical classes medicine, makes Preparation Method is simple, and this Chinese medicine feed additive residual rate is low, toxicity is low, does not affect the quality of Ctenopharyngodon idellus, is not detrimental to health.
(3) the Fish Chinese medicine feed additive preparation method of the present invention simple it is easy to large-scale promotion and application.
Specific embodiment
With reference to specific embodiment, the specific embodiment of the present invention is described in detail, it is to be understood that the present invention Protection domain do not limited by specific embodiment.
Embodiment 1
A kind of Fish Chinese medicine feed additive, by being made up of following components by weight:10 parts of Radix Angelicae Sinensis, 8 parts of Radix Polygoni Multiflori, meat 9 parts of Fructus Amomi Rotunduss, 7 parts of Flos Chrysanthemi, 15 parts of Herba Ephedrae, 8 parts of Rhizoma Et Radix Notopterygii, 25 parts of Radix Bupleuri, 10 parts of Fructus Aurantii Immaturus and 6 parts of Olibanum.
The preparation method of described Fish Chinese medicine feed additive, comprises the following steps:
(1) weigh by weight Radix Angelicae Sinensis in formula, Radix Polygoni Multiflori, Semen Myristicae, Flos Chrysanthemi, Herba Ephedrae, Rhizoma Et Radix Notopterygii, Radix Bupleuri, Fructus Aurantii Immaturus, Olibanum, is cleaned and dries, after being pulverized and mixed by pulverizer, add the tap water of its 3 times of weight, first boil slow fire again by intense fire and endure 0.5h, after filtration first filtrate, add the tap water of 2 times of its weight toward medicinal residues, boil rear slow fire by intense fire and endure 0.5h, pour out the Secondary filtrate, merges and is concentrated to give herb liquid study after filtrate twice;
(2) add the dehydrated alcohol of 3 times of its volume in the herb liquid study of step (1) gained, stirring and dissolving dilutes, Flow back at a temperature of 85 DEG C 2.5h, obtains refined herb liquid;
(3) take the refined herb liquid of step (2) gained, after decompression recycling ethanol, by herb liquid low-temperature evaporation, obtain latex shape Middle medicinal substances, glue milky substance are put in drying machine and are dried, and inlet temperature is 130 DEG C, and leaving air temp is 75 DEG C, obtains powder Material, powdered rubber is crushed to 120 mesh, obtains Chinese medicinal powder;
(4) Chinese medicinal powder of step (3) gained is admixed the Semen Maydis powder of 2 times of its quality, mix, carry out expanded, temperature control Make at 85 DEG C, expanded time 1min, subsequent pelletize, cooling, treat that particulate component is cooled to 20 DEG C, packaging, obtain final product Fish Chinese medicine and raise Feed additives.
Embodiment 2
A kind of Fish Chinese medicine feed additive, by being made up of following components by weight:30 parts of Radix Angelicae Sinensis, 16 parts of Radix Polygoni Multiflori, 18 parts of Semen Myristicae, 21 parts of Flos Chrysanthemi, 30 parts of Herba Ephedrae, 15 parts of Rhizoma Et Radix Notopterygii, 35 parts of Radix Bupleuri, 25 parts of Fructus Aurantii Immaturus and 15 parts of Olibanum.
The preparation method of described Fish Chinese medicine feed additive, comprises the following steps:
(1) weigh by weight Radix Angelicae Sinensis in formula, Radix Polygoni Multiflori, Semen Myristicae, Flos Chrysanthemi, Herba Ephedrae, Rhizoma Et Radix Notopterygii, Radix Bupleuri, Fructus Aurantii Immaturus, Olibanum, is cleaned and dries, after being pulverized and mixed by pulverizer, add the tap water of its 4 times of weight, first boil slow fire again by intense fire and endure 1h, obtains first filtrate, adds the tap water of 3 times of its weight toward medicinal residues, boil rear slow fire by intense fire and endure 0.5h, pour out second after filtration Secondary filtrate, merges and is concentrated to give herb liquid study after filtrate twice;
(2) add the dehydrated alcohol of 5 times of its volume in the herb liquid study of step (1) gained, stirring and dissolving dilutes, Flow back at a temperature of 95 DEG C 3.5h, obtains refined herb liquid;
(3) take the refined herb liquid of step (2) gained, after decompression recycling ethanol, by herb liquid low-temperature evaporation, obtain latex shape Middle medicinal substances, glue milky substance are put in drying machine and are dried, and inlet temperature is 150 DEG C, and leaving air temp is 90 DEG C, obtains powder Material, powdered rubber is crushed to 120 mesh, obtains Chinese medicinal powder;
(4) Chinese medicinal powder of step (3) gained is admixed the Semen Maydis powder of 3 times of its quality, mix, carry out expanded, temperature control Make at 90 DEG C, expanded time 2min, subsequent pelletize, cooling, treat that particulate component is cooled to 25 DEG C, packaging, obtain final product Fish Chinese medicine and raise Feed additives.
Embodiment 3
A kind of Fish Chinese medicine feed additive, by being made up of following components by weight:20 parts of Radix Angelicae Sinensis, 12 parts of Radix Polygoni Multiflori, 15 parts of Semen Myristicae, 14 parts of Flos Chrysanthemi, 25 parts of Herba Ephedrae, 12 parts of Rhizoma Et Radix Notopterygii, 30 parts of Radix Bupleuri, 20 parts of Fructus Aurantii Immaturus and 9 parts of Olibanum.
The preparation method of described Fish Chinese medicine feed additive, comprises the following steps:
(1) weigh by weight Radix Angelicae Sinensis in formula, Radix Polygoni Multiflori, Semen Myristicae, Flos Chrysanthemi, Herba Ephedrae, Rhizoma Et Radix Notopterygii, Radix Bupleuri, Fructus Aurantii Immaturus, Olibanum, is cleaned and dries, after being pulverized and mixed by pulverizer, add the tap water of its 3.5 times of weight, first boil slow fire again by intense fire and endure 0.8h, obtains first filtrate, adds the tap water of 2.5 times of its weight toward medicinal residues, boil rear slow fire by intense fire and endure 0.5h, pour out after filtration Second filtrate, merges and is concentrated to give herb liquid study after filtrate twice;
(2) add the dehydrated alcohol of 4 times of its volume in the herb liquid study of step (1) gained, stirring and dissolving dilutes, Flow back at a temperature of 90 DEG C 3.0h, obtains refined herb liquid;
(3) take the refined herb liquid of step (2) gained, after decompression recycling ethanol, by herb liquid low-temperature evaporation, obtain latex shape Middle medicinal substances, glue milky substance are put in drying machine and are dried, and inlet temperature is 140 DEG C, and leaving air temp is 80 DEG C, obtains powder Material, powdered rubber is crushed to 120 mesh, obtains Chinese medicinal powder;
(4) Chinese medicinal powder of step (3) gained is admixed the Semen Maydis powder of 2.5 times of its quality, mix, carry out expanded, temperature Control at 88 DEG C, expanded time 1-2min, subsequent pelletize, cooling, treat that particulate component is cooled to 22 DEG C, packaging, obtain final product in Fish Medicine feed additive.
Embodiment 4:The Fish Chinese medicine feed additive of the present invention is tested to survival rate
Experimental animal:Test Ctenopharyngodon idellus are purchased from Nanning City fish farm, are juvenile fish, body weight 80-86g/ tail, selected test fry Number is 4000 tails, and health is strong, and male and female all have.4000 tail Ctenopharyngodon idellus are randomly divided into four groups:Test group 1-3 and matched group, every group Containing juvenile fish 1000 tail.
Test feed:The test group 1-3 Chinese medicine feed additive mixed fodder that respectively prepared by feeding embodiment of the present invention 1-3 (will 150g above-described embodiment 1-3 preparation Chinese medicine feed additive, 80g soybean cake, 350g wheat flour, 35g crab shell powder, 60g shrimp Powder, 10g Sal, 160g Semen Maydis powder, 30g fish oil, 15g glycine betaine, 2g dalcium biphosphate, 2g ferric citrate, 40g compound vitamin B, 30g yeast, 20g threonine, 20g lysine, mix homogeneously);The feedstuff of matched group feeding is with the difference of test group:Make Replace the Chinese medicine feed additive that the present invention uses with bambermycin 20mg/kg.
Feeding method:Date of test is 8 days-October 22 May in 2015.Ctenopharyngodon idellus cultivate in fish pond, stocking density 1 Bar/20L.Fish pond area 1500m2(long 50m × wide 30m), deep 80cm, with bamboo fence, (water can pass through, and fish can not be by for marking Accurate) all separate and block into 375m24 blockages;Whole average 16 DEG C of fish pond coolant-temperature gage (wherein 24-29 DEG C of summer, average 25.5 DEG C), pH value 6.5 ± 0.2, water quality meets fishery standard.
3-5% is quantitatively of fixed place and time feeds by fry weight for feedstuff day feeding volume, feeds 2 times/d, every 10d dosage 1 time.Adjust Look into the survival rate of Ctenopharyngodon idellus, the results are shown in Table 1.
The impact to Ctenopharyngodon idellus survival rate for the Fish Chinese medicine feed additive of table 1 present invention
Group Survival number (tail) Death toll (tail) Survival rate (%)
Test group 1 986 14 98.6
Test group 2 989 11 98.9
Test group 3 980 20 98.0
Matched group 810 180 81.0
As it can be seen from table 1 using the Chinese medicine feed additive feeding Ctenopharyngodon idellus of present invention preparation, its ill probability fall Low, survival rate is significantly higher than matched group.
The description of the aforementioned specific illustrative embodiment to the present invention illustrate that and illustration purpose.These descriptions It is not wishing to limit the invention to disclosed precise forms, and it will be apparent that according to above-mentioned teaching, can much be changed And change.The purpose of selecting and describing the exemplary embodiment is that explaining that the certain principles of the present invention and its reality should With so that those skilled in the art be capable of and utilize the present invention various different exemplary and Various different selections and change.The scope of the present invention is intended to be limited by claims and its equivalents.

Claims (3)

1. a kind of Fish Chinese medicine feed additive is it is characterised in that by being made up of following components by weight:Radix Angelicae Sinensis 10-30 part, Radix Polygoni Multiflori 8-16 part, Semen Myristicae 9-18 part, Flos Chrysanthemi 7-21 part, Herba Ephedrae 15-30 part, Rhizoma Et Radix Notopterygii 8-15 part, Radix Bupleuri 25-35 part, Fructus Aurantii Immaturus 10-25 part and Olibanum 6-15 part.
2. Fish Chinese medicine feed additive according to claim 1 is it is characterised in that by by weight by following components system Become:20 parts of Radix Angelicae Sinensis, 12 parts of Radix Polygoni Multiflori, 15 parts of Semen Myristicae, 12 parts of Flos Chrysanthemi, 25 parts of Herba Ephedrae, 11 parts of Rhizoma Et Radix Notopterygii, 30 parts of Radix Bupleuri, Fructus Aurantii Immaturus 20 Part and 10 parts of Olibanum.
3. the preparation method of Fish Chinese medicine feed additive according to claim 1 and 2 is it is characterised in that include following Step:
(1) Radix Angelicae Sinensis in formula, Radix Polygoni Multiflori, Semen Myristicae, Flos Chrysanthemi, Herba Ephedrae, Rhizoma Et Radix Notopterygii, Radix Bupleuri, Fructus Aurantii Immaturus, breast are weighed by weight Perfume (or spice), is cleaned and dries, after being pulverized and mixed by pulverizer, add the tap water of its 3-4 times of weight, first boil slow fire again by intense fire and endure 0.5-1h, obtains first filtrate, adds the tap water of its weight 2-3 times toward medicinal residues, boil rear slow fire by intense fire and endure 0.5h, after filtration Go out second filtrate, merge and be concentrated to give herb liquid study after filtrate twice;
(2) add the dehydrated alcohol of its volume 3-5 times in the herb liquid study of step (1) gained, stirring and dissolving dilutes, Flow back at a temperature of 85-95 DEG C 2.5-3.5h, obtains refined herb liquid;
(3) take the refined herb liquid of step (2) gained, after decompression recycling ethanol, by herb liquid low-temperature evaporation, obtain latex shape Chinese medicine Material, glue milky substance is put in drying machine and is dried, and inlet temperature is 130-150 DEG C, and leaving air temp is 75-90 DEG C, obtains Powdered rubber, powdered rubber is crushed to 120 mesh, obtains Chinese medicinal powder;
(4) Chinese medicinal powder of step (3) gained is admixed the Semen Maydis powder of its quality 2-3 times, mix, carry out expanded, temperature control At 85-90 DEG C, expanded time 1-2min, subsequent pelletize, cooling, treat that particulate component is cooled to 20-25 DEG C, packaging, obtain final product Fish Chinese medicine feed additive.
CN201611032264.0A 2016-11-22 2016-11-22 Traditional Chinese medicine feed additive for fish and preparation method thereof Pending CN106387514A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107242372A (en) * 2017-06-26 2017-10-13 宁国市仙之居家庭农场 A kind of Chinese medicine fodder and preparation method of piglet growth phase
CN107549468A (en) * 2017-10-26 2018-01-09 覃远梅 A kind of fish Chinese herbal feed additive and preparation method thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101124945A (en) * 2007-09-27 2008-02-20 天津农学院 Special-purpose traditional Chinese medicinal composition for fresh water fish infectious diseases
CN104054973A (en) * 2014-07-08 2014-09-24 明光市永言水产食品有限公司 Feed used for improving immune function of carp
CN104171725A (en) * 2014-08-15 2014-12-03 徐州福润禽业食品有限公司 Traditional Chinese medicine hen feed capable of improving egg quality and processing method of feed
CN106071351A (en) * 2016-06-03 2016-11-09 开县千山科技开发有限公司 A kind of feed of grass carp and preparation method thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101124945A (en) * 2007-09-27 2008-02-20 天津农学院 Special-purpose traditional Chinese medicinal composition for fresh water fish infectious diseases
CN104054973A (en) * 2014-07-08 2014-09-24 明光市永言水产食品有限公司 Feed used for improving immune function of carp
CN104171725A (en) * 2014-08-15 2014-12-03 徐州福润禽业食品有限公司 Traditional Chinese medicine hen feed capable of improving egg quality and processing method of feed
CN106071351A (en) * 2016-06-03 2016-11-09 开县千山科技开发有限公司 A kind of feed of grass carp and preparation method thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107242372A (en) * 2017-06-26 2017-10-13 宁国市仙之居家庭农场 A kind of Chinese medicine fodder and preparation method of piglet growth phase
CN107549468A (en) * 2017-10-26 2018-01-09 覃远梅 A kind of fish Chinese herbal feed additive and preparation method thereof

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Application publication date: 20170215