CN105995179A - Preparing method for traditional Chinese medicine feed additive in laying hen growing period - Google Patents

Preparing method for traditional Chinese medicine feed additive in laying hen growing period Download PDF

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CN105995179A
CN105995179A CN201610521543.7A CN201610521543A CN105995179A CN 105995179 A CN105995179 A CN 105995179A CN 201610521543 A CN201610521543 A CN 201610521543A CN 105995179 A CN105995179 A CN 105995179A
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chinese medicine
ethanol
feed additive
laying hen
preparation
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程磊
贾松涛
梁延朝
丁玉兰
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Abstract

The invention relates to a preparing method for a traditional Chinese medicine feed additive in the laying hen growing period. Traditional Chinese medicine honeysuckle flower, indigo naturalis, glossy privet fruit, herba leonuri, coptis chinensis, mexican tea herb, dried tangerine or orange peel, radix sophorae flavescentis, scorched hawthorn fruit, radix astragali, radix angelica sinensis, hyodeoxycholic acid and liquorice root are taken and smashed in a superfine mode, an ethanol solution is added and boiled with strong fire, soft fire is used for heat preservation, the mixed solution is cooled and filtered, filter liquor is concentrated, white sugar is added, the concentrated liquor is boiled, cooled to normal temperature and inoculated with lactobacillus, acetobacter xylinum and saccharomycetes, fermentation is carried out until white fungus blocks grow out, and fungus liquor is concentrated at low temperature; modified starch, Arabic gum, cyclodextrin and syrup are weighed and added into the concentrated fungus liquor in a stirred mode, after the mixture is mixed and stirred uniformly, high pressure homogenization and spray drying are carried out to obtain the traditional Chinese medicine feed additive. The traditional Chinese medicine feed additive has an obvious weight gaining effect, increases effective microbial community in the intestinal tract, improves the immunologic function and reduces collective prevention administration dosage. The age of the first egg is put ahead of time by 3-5 days compared with a control group, egg weight is increased by 2-4 g, feed is saved, cost is reduced, and economic benefits of breeding are increased.

Description

A kind of preparation method of laying hen finishing period Chinese medicine feed additive
Technical field
The invention belongs to field of feed, particularly relate to the preparation method of a kind of laying hen finishing period Chinese medicine feed additive.
Background technology
Development along with breeding layer chicken industry, requirement to egg feedstuff is more and more higher, especially laying hen is bred as the critical stage that feedstuff is the whole laying hen production cycle, and the quality of Chicks ' Growth is directly connected to regularity and the laying rate of Growing Chicken, thus affects the production performance of hen.Research shows: 10 week old body weight are proportionate with persistency of laying eggs, and O.82 correlation coefficient is；Being proportionate with 60 week old survival rates, correlation coefficient is 0.71.Laying chickling is in the moult for the first time of 4-10 week old stage, this stage Chicks ' Growth is rapid, the 85% of whole growth cycle is accounted for 8 week old skeleton developments, 6-10 week old is the important period of development of muscle, tendon, ligament, as can be seen here, meeting laying hen and be bred as the nutritional need in stage, the performance to laying hen lifetime performance is most important.
Feedstuff is healthy for laying hen chicken body and body weight increase be skeleton development etc. be extremely critical, in view of problems such as the prevention of disease in finishing period chicken growth course and controls in prior art, occur in that some feed additives, but these products add mainly hormone medicine or other additives, such as antibiotic, hormone, high copper additives etc., see it is to solve some problems in a short time, but actually result in Egg Quality drastically to decline, it is often more important that can be to the healthy public harm causing tool big of people；It addition, these additives of life-time service can cause the Drug resistance of chicken, and it is unfavorable for digesting and assimilating of chicken, the problems such as palatability is poor.
Chinese invention patent CN103349179A provides and discloses a kind of laying hen finishing period complete feed, it is made up of the component of following weight portion: Semen Maydis 350～450 parts, Semen Tritici aestivi 150～200 parts, bean cake 50～100 parts, Semen arachidis hypogaeae dregs 10～40 parts, cottonseed meal 30～40 parts, rapeseed cake 10～30 parts, maize gluten feed 40～60 parts, DDGS (distiller grains) 40～80 parts, rice bran meal 70～150 parts, stone powder 15～25 parts, bone meal 10～25 parts, Oleum Glycines 5～6 parts, calcium hydrogen phosphate 6～10 parts, Sal 2.5～3 parts, sodium sulfate 1～2 parts, choline 0.5～1 part, compound microelement 2 parts, lysine 2～5 parts, methionine 1～1.5 parts, additive 1.3 parts.The chicken finishing period complete feed of the present invention, low cost, after feeding laying hen, laying hen opens antenatal body weight and can reach or exceed breed standard, and body maturation is Tong Bu with sexual maturity.Add is all the feed additives such as conventional aminoacid, trace element and mineral, does not add Chinese medicine and probiotics, does not the most use Chinese medicine and carries out the incidence rate reaching to prevent to reduce disease of fermenting.
Chinese invention patent CN103689250A provides a kind of Pullet special feed, this feedstuff is prepared by the raw material of following percentage by weight: Semen Maydis 150-180 part, Sorghum vulgare Pers. wheat-middlings 35-40 part, bean cake 45-50 part, Oryza glutinosa 50-60 part, Testa oryzae 45-50 part, palm kernel dregs of rice 55-60 part, peanut straw 45-50 part, Os Sus domestica powder 2-3 part, zeolite 1-2 part, Semen Fructus Chaenomelis 3-4 part, pearl white 1-2 part, Kelp Powder 2-3 part, little Hemerocallis citrina Baroni cauliflower 4-5 part, Rhizoma Imperatae 4-5 part, Mulberry 5-6 part, dry Hemisalanx powder 2-3 part, butter 2-3 part, bean worm powder 2-3 part, Herba Sonchi Oleracei 3-4 part, proper amount of salt, phagostimulant 4-5 part.The egg feedstuff that the present invention provides, protein component and the equilibrium of energy component ratio, the composition containing several amino acids, vitamin and trace element such as the Semen Fructus Chaenomelis of interpolation, Kelp Powder, little Hemerocallis citrina Baroni cauliflower, Hemisalanx powder, butter, effectively avoid Pullet and overfertilization or the thinnest situation occur, ensure that the normal growth promoter of laying hen, the day laying rate of laying hen improves, and ovipository cycle extends.Simply various nutritional labelings are carried out proportioning, adds Semen Fructus Chaenomelis, Kelp Powder, little Hemerocallis citrina Baroni cauliflower, Hemisalanx powder, butter etc., the most do not use Chinese medicine, more Chinese medicine is not fermented through microorganism, reach the common effect of existing Chinese medicine and probiotic bacteria.
During intensive animal feeding, Chinese herbal medicine replaces antibiotic to effectively reduce drug residue problem during animal feeding, and the appearance of biofermentation traditional Chinese medicine technology, the drug effect making Chinese herbal medicine improves 4-20 times, and gradually shows more significantly effect at aspects such as prevention disease and raising production performances.
Accordingly, it would be desirable to a kind of growth promoter that can meet laying hen finishing period, good palatability, promoting laying hen finishing period healthy growth, can improve again survival rate and the uniformity of Growing Chicken, the new feedstuff that will not work the mischief health is to solve existing issue.
Summary of the invention
Present invention aims to the deficiency of above technology, solve current laying chickling survival rate, the uniformity and the problem of anti-stress, thering is provided the preparation method of a kind of laying hen finishing period feedstuff, the method is simple, it is easy to use to have, green safety, noresidue, pure ecology, viable bacteria content are high.
For reaching above-mentioned purpose, the technical solution used in the present invention is as follows:
nullA kind of preparation method of laying hen finishing period Chinese medicine feed additive，It is characterized in that: it is to prepare according to the following steps: one、Chinese medicine extract: weigh the Flos lonicerae 120-140 of following weight portion、Indigo Naturalis 120-140、Fructus Ligustri Lucidi 120-140、Herba Leonuri 120-140、Rhizoma Coptidis 100-120、Herba Chenopodii 100-120、Pericarpium Citri Reticulatae 100-120、Radix Sophorae Flavescentis 100-120、Fructus Crataegi (parched to brown) 80-100、Radix Astragali 80-100、Radix Angelicae Sinensis 80-100、Hyodeoxycholic Acid 60-80、Radix Glycyrrhizae 40-60，Each Study on Supermicro-pulverization of Traditional Chinese Drugs is added ethanol solution intense fire boil，Slow fire is incubated，Cold filtration，Concentrated filtrate，Add white sugar to boil，Cool down to inoculating lactobacillus after room temperature、Acetobacter xylinum and yeast，Through 96 ~ 120h fermentation to growing white truffle，By bacterium solution cryoconcentration；Two, microcapsule is coated: weigh the microcapsule wall material modified starch 45-55 of following weight portion, arabic gum 15-20, beta-schardinger dextrin-15-20, syrup 25-30, join in the bacterium solution that 400-500kg concentrates, stirring while adding, after mixing and stirring, high pressure homogenize, it is spray-dried, obtains laying hen finishing period Chinese medicine feed additive, add in laying hens essential ration by 4%-8%.
The preparation method of described a kind of laying hen finishing period Chinese medicine feed additive, it is characterized in that: weigh the Chinese medicine of weight portion in proportion, by its micronizing, the ethanol solution of 80%～the 90% of addition Chinese medicine gross weight 6～8 times amount, soak 30～60min, intense fire boils, slow fire insulation 30～60min, cools down Floor 12 filtered through gauze；Filtering residue adds 4～the ethanol solution of the 60% of 6 times amount～70% again, intense fire boils, slow fire insulation 30～60min, cooling Floor 12 filtered through gauze, merge twice filtrate, concentration and recovery ethanol, concentrates without stopping during ethanol with in ethanol detector detection concentrated solution, adds water and make every milliliter of water crude drug Han 0.25g in concentrated solution.
The preparation method of described a kind of laying hen finishing period Chinese medicine feed additive, it is characterized in that: in units of 100 Kg concentrated solutions, add white sugar 10～20Kg, and boil 3～5min, it is cooled to room temperature, inoculating lactobacillus, acetobacter xylinum and yeast (commercially available) preparation 20～25Kg, setting fermentation temperature 35～38 DEG C, standing for fermentation cultivates 96～120h, growing white truffle to pH5.5 ~ 6.5, cryoconcentration, make every gram containing 0.5 gram of crude drug.
The preparation method of described a kind of laying hen finishing period Chinese medicine feed additive, it is characterised in that: the pressure 10-20MPa of high pressure homogenize, time 3-5min.
The preparation method of described a kind of laying hen finishing period Chinese medicine feed additive, it is characterised in that: spraying feeding temperature 50-60 DEG C, feed rate 15-20L/min, inlet temperature 185-190 DEG C, leaving air temp 60-70 DEG C.
The preparation method of described a kind of laying hen finishing period Chinese medicine feed additive, it is characterised in that: step one is carried out in aseptic fermenting cellar.
Feedstuff of the present invention has profitable strain quantity in increase intestinal, improves immunologic function, strengthens chicken body anti-stress, premunition, increase egg production, improves the effects such as qualified egg rate, and preparation method is simple, easy to use, noresidue.Beneficial effects of the present invention is good to the prevention effect of Pullorum Disease and newcastle disease, and control rate reaches 95.0%, meanwhile, also has certain preventive effect and viable bacteria content high to coccidiosis, and content of microorganisms is 5.85 × 10 after measured9Cfu/g, the survival rate of the microorganism after high temperature granulating is more than 90%.
The viable bacteria content of the Chinese medicine feed additive probiotics of the present invention is high, the aseptic 0.1g preparation that weighs, and adds in 10ml diluent, fully shake up, make 10 times of serial dilutions, take last dilution factor 1ml, instill on selectivity agar culture plate, each dilution factor, make 3 plates, and with the coating of L-shaped glass rod uniformly, put and constant incubator is cultivated under the conditions of 37 DEG C 24～48h, cultivation expires and observes each plate colony growth situation, and counts.By the content of slaking test detection probiotic bacteria, determine optimal capsule diameter；After testing after fermentation, after dried, high temperature does not embeds granulation, high temperature embedding pelletize after, viable bacteria content after high temperature granulating commercially available, commercially available the results are shown in Table 1.
Table 1 viable bacteria content test results report
Group Viable count (cfu/g)
After fermentation 3.2×108cfu/g
After drying 3.5×1010cfu/g
High temperature does not embeds granulation 1.7×105cfu/g
High temperature embedding is pelletized 4.3×107cfu/g
Commercially available 1.3×1010cfu/g
After commercially available high temperature granulating 1.5×105cfu/g
After fermenting as can be seen from Table 2, medicinal liquid viable count content is 3.2 × 108Cfu/g, after low-temperature vacuum drying, viable bacteria content is 3.5 × 1010Cfu/g, this is consistent with dried yield (recovery rate 10%), does not embeds the viable count content after pelletizing 1.7 × 10 through high temperature5After cfu/g, with commercially available high temperature granulating, viable count is suitable, and the viable count after high temperature granulating after embedding is 2.1 × 107-4.3×107Cfu/g exceeds two orders of magnitude than the viable count not embedded, and reaches every gram of viable count more than million, thus, solve the commercial preparation unstable problem to high temperature.
The present invention controlling experiment to infected chicken Hakuri: experimental chicken is Luo Man brown shell layer 200 plumage, body weight 600～800g, Salmonella merit poison 150 plumages, 4 groups are divided at random by it, it is divided into positive controls, negative control group, antibiotic matched group (oxytetracycline), feedstuff group of the present invention, often organizing each 50 plumages, experimental period is 5 days；Antibiotic matched group oxytetracycline soluble powder adds in feedstuff by 0.2%, feminine gender and positive controls other components in addition to feedstuff of the present invention, it is used in conjunction 5 days, Continuous Observation 5 days, during test, each group feeding and management condition is the most identical, observes the clinical symptoms of each group of chicken, searches for food, drinks water, the situation such as spirit, feces, curative effect determinate standard is: spirit, diet, defecation recover normal, and symptom is wholly absent and is judged to cure；Spirit, diet, defecation take a favorable turn, and symptom substantially alleviates, and are judged to effectively；Symptom is even dead without taking a turn for the better, and cuts open inspection, and it is invalid to be judged to, and the results are shown in Table 2.
The table 2 feedstuff of the present invention therapeutic effect to artificial challenge's Pullorum Disease
Group Quantity (plumage) Cure number (plumage) Significant figure (plumage) Death toll (plumage) Cure rate (%)
Feedstuff group of the present invention 50 48 49 0 96.0
Antibiotic matched group 50 49 49 1 98.0
Positive controls 50 14 21 29 28.0
Negative control group 50 100 100 0 100.0
As can be seen from Table 2: feedstuff group of the present invention and antibiotic matched group be not more notable (P < 0.05) than difference.Illustrate that this feedstuff has preferable preventive and therapeutic effect to Pullorum Disease, Pullorum Disease can be prevented and treated with substitute antibiotics, solve the drug resistance problems of antibiotic.And easy to use, economical and practical, environmental protection.Chinese prescription of the present invention has the functions such as bacteriostasis and sterilization, eliminating pathogenic heat from blood to cure dysentery, damp eliminating, anti-stress, modern pharmacology shows: in Fang, Flos Lonicerae, Rhizoma Coptidis have the most antibacterial and bactericidal action, Indigo Naturalis has stronger antivirus action, the tissue injury caused by virus infection can be treated, increase the pharmacological action of bile secretion, Fructus Crataegi (parched to brown), Pericarpium Citri Reticulatae, Massa Medicata Fermentata, the Radix Astragali, Radix Angelicae Sinensis have anti-stress effect, Fructus Ligustri Lucidi, Herba Leonuri, Radix Angelicae Sinensis have enhancing human body immunity power, improve the resistance against diseases of chicken body, Radix Glycyrrhizae is to make medicine, make all medicines return through effect.
Beneficial effects of the present invention alleviates salpingitis tubal reaction to a certain extent, has good repair, tumor necrosis factor TNF-alpha and epidermal growth factor EGFR to reduce 43.62% and 18.59% compared with matched group respectively the damage of laying chickling fallopian tube.
TNF-α and the impact of EGFR content in present invention laying hen brown on Luo Man oviduct tissue, experimental chicken is Luo Man brown shell layer 400 plumage, body weight 700～800g, 4 groups are divided at random by it, it is divided into matched group, 4% interpolation group, 5% interpolation group, 6% interpolation group, often organize each 100 plumages, experimental period from the beginning of within 6 weeks, feeding, until terminate for 8 weeks.8 week old ends, respectively repeat to randomly draw 5 chickens and carry out cuing open killing, aseptic separation oviduct tissue, accurately weigh oviduct tissue 1g, add 2mlPBS solution, after ice bath homogenate, and 4 DEG C of 12000r/min, centrifugal 10min, take supernatant standby.Use ELISA kit to measure TNF-α and EGFR content in oviduct tissue, the results are shown in Table 3.
TNF-α and the impact of EGFR content in table 3 feedstuff of the present invention laying hen brown on Luo Man oviduct tissue
Index Matched group 4% interpolation group 5% interpolation group 6% interpolation group
TNF-α 52.78±3.08 42.78±5.16 29.76±3.53 40.66±3.64
EGFR 189.73±5.63 171.23±6.24 156.45±5.83 162.56±8.73
Whether the health of laying chickling oviduct tissue directly affects adult laying rate of laying hen and Egg Quality.Being a kind of commonly encountered diseases of laying hen by bacterial hens salpingitis such as escherichia coli, result shows, has the infiltration of substantial amounts of neutrophilic granulocyte and lymphocyte, cell damage, there occurs inflammatory reaction in matched group laying hen oviduct tissue.Test group layer diets adds the feedstuff of 5% present invention reduce inflammation to a certain extent reaction, especially preferable with 5% group of effect, after using this compound preparation, the damage of laying hen fallopian tube there is is good repair.
The present invention has the beneficial effects that Age at first laying relatively matched group shifts to an earlier date 3-5d respectively, and egg size increases 2-4g respectively, saved feedstuff, reduce cost, improves fanning economics.Present invention test is carried out in breeding layer chicken field, the Huaibei.Select Luo Man brown shell layer 200 plumage that 18 and 20 week old are healthy, identical week old laying hen is randomly divided into test group and matched group, often organize 100 plumages, test group uses the pellet of present invention preparation, oneself formula feed of control group fed chicken house, 20 days experimental periods, the open raising of full staged chicken coop is used in confined poultry house, carrying out artificial breeding, morning and afternoon every day respectively feeds a feedstuff, freely drinks water.Artificial lighting every day 18h, average house temperature 26 DEG C, medial humidity 65%, intensity of illumination average out to 14lx, exhaust ventilation in house.Recording egg number, egg size, feed consumption rate every day, calculate average egg weight, feedstuff-egg ratio, result of the test is shown in Table 4.
Average egg weight on Luo Man brown shell layer of table 4, the present invention, the impact of feedstuff-egg ratio
As can be seen from Table 4,2 groups of laying rate and egg size difference is not notable (P > 0.05), and test group egg size, than matched group 2.66g and 3.23g, illustrates that the present invention is fine to oviducal protected effect, reduces the inflammation damage to oviduct tissue.
Detailed description of the invention
Embodiment 1
A kind of preparation method of laying hen finishing period Chinese medicine feed additive, comprise the following steps: one, Chinese medicine extract: weigh the Flos lonicerae 120 of following weight portion, Indigo Naturalis 120, Fructus Ligustri Lucidi 120, Herba Leonuri 120, Rhizoma Coptidis 100, Herba Chenopodii 100, Pericarpium Citri Reticulatae 100, Radix Sophorae Flavescentis 100, Fructus Crataegi (parched to brown) 80, the Radix Astragali 80, Radix Angelicae Sinensis 80, Hyodeoxycholic Acid 60, Radix Glycyrrhizae 40, by the ethanol solution of the 80% of each Study on Supermicro-pulverization of Traditional Chinese Drugs addition Chinese medicine gross weight 6 times amount, soak 30min, intense fire boils, slow fire insulation 30min, cools down Floor 12 filtered through gauze；Filtering residue adds the ethanol solution of the 60% of 4 times amount again, and intense fire boils, slow fire insulation 30min, cooling Floor 12 filtered through gauze, merges twice filtrate, concentration and recovery ethanol, concentrate without stopping during ethanol with in ethanol detector detection concentrated solution, add water in concentrated solution and make every milliliter of water crude drug Han 0.25g.White sugar 10Kg is added in units of 100 Kg concentrated solutions, and boil 3min, it is cooled to room temperature, inoculating lactobacillus, acetobacter xylinum and yeast (commercially available) preparation 20Kg, setting fermentation temperature 35 DEG C, standing for fermentation cultivates 96h, growing white truffle to pH5.5, cryoconcentration, makes every gram containing 0.5 gram of crude drug.Two, microcapsule is coated: weigh the microcapsule wall material modified starch 45 of following weight portion, arabic gum 15, beta-schardinger dextrin-15, syrup 25, joins 400kg and concentrates in bacterium solution, stirring while adding, after mixing and stirring, high pressure homogenize, pressure 10MPa, time 3min, is spray-dried, and sets feeding temperature 50 DEG C, feed rate 15L/min, inlet temperature 185 DEG C, leaving air temp 60 DEG C, cool, obtain laying hen finishing period Chinese medicine feed additive, by 4% basal diet adding laying hen to.
Embodiment 2
A kind of preparation method of laying hen finishing period Chinese medicine feed additive, comprise the following steps: one, Chinese medicine extract: weigh the Flos lonicerae 120 of following weight portion, Indigo Naturalis 120, Fructus Ligustri Lucidi 120, Herba Leonuri 120, Rhizoma Coptidis 100, Herba Chenopodii 100, Pericarpium Citri Reticulatae 100, Radix Sophorae Flavescentis 100, Fructus Crataegi (parched to brown) 80, the Radix Astragali 80, Radix Angelicae Sinensis 80, Hyodeoxycholic Acid 60, Radix Glycyrrhizae 40, by the ethanol solution of the 80% of each Study on Supermicro-pulverization of Traditional Chinese Drugs addition Chinese medicine gross weight 6 times amount, soak 60min, intense fire boils, slow fire insulation 30min, cools down Floor 12 filtered through gauze；Filtering residue adds the ethanol solution of the 70% of 4 times amount again, and intense fire boils, slow fire insulation 60min, cooling Floor 12 filtered through gauze, merges twice filtrate, concentration and recovery ethanol, concentrate without stopping during ethanol with in ethanol detector detection concentrated solution, add water in concentrated solution and make every milliliter of water crude drug Han 0.25g.White sugar 12Kg is added in units of 100 Kg concentrated solutions, and boil 4min, it is cooled to room temperature, inoculating lactobacillus, acetobacter xylinum and yeast (commercially available) preparation 21Kg, setting fermentation temperature 36 DEG C, standing for fermentation cultivates 108h, growing white truffle to pH6.0, cryoconcentration, makes every gram containing 0.5 gram of crude drug.Two, microcapsule is coated: weigh the microcapsule wall material modified starch 48 of following weight portion, arabic gum 16, beta-schardinger dextrin-16, syrup 26, joins 410kg and concentrates in bacterium solution, stirring while adding, after mixing and stirring, high pressure homogenize, pressure 11MPa, time 3min, is spray-dried, and sets feeding temperature 51 DEG C, feed rate 16L/min, inlet temperature 186 DEG C, leaving air temp 61 DEG C, cool, obtain laying hen finishing period Chinese medicine feed additive, by 5% basal diet adding laying hen to.
Embodiment 3
A kind of preparation method of laying hen finishing period Chinese medicine feed additive, comprise the following steps: one, Chinese medicine extract: weigh the Flos lonicerae 120 of following weight portion, Indigo Naturalis 120, Fructus Ligustri Lucidi 120, Herba Leonuri 120, Rhizoma Coptidis 100, Herba Chenopodii 100, Pericarpium Citri Reticulatae 100, Radix Sophorae Flavescentis 100, Fructus Crataegi (parched to brown) 80, the Radix Astragali 80, Radix Angelicae Sinensis 80, Hyodeoxycholic Acid 60, Radix Glycyrrhizae 40, by the ethanol solution of the 80% of each Study on Supermicro-pulverization of Traditional Chinese Drugs addition Chinese medicine gross weight 6 times amount, soak 30min, intense fire boils, slow fire insulation 60min, cools down Floor 12 filtered through gauze；Filtering residue adds the ethanol solution of the 60% of 5 times amount again, and intense fire boils, slow fire insulation 30min, cooling Floor 12 filtered through gauze, merges twice filtrate, concentration and recovery ethanol, concentrate without stopping during ethanol with in ethanol detector detection concentrated solution, add water in concentrated solution and make every milliliter of water crude drug Han 0.25g.White sugar 14Kg is added in units of 100 Kg concentrated solutions, and boil 5min, it is cooled to room temperature, inoculating lactobacillus, acetobacter xylinum and yeast (commercially available) preparation 22Kg, setting fermentation temperature 37 DEG C, standing for fermentation cultivates 110h, growing white truffle to pH6.5, cryoconcentration, makes every gram containing 0.5 gram of crude drug.Two, microcapsule is coated: weigh the microcapsule wall material modified starch 47 of following weight portion, arabic gum 17, beta-schardinger dextrin-17, syrup 27, adds 420kg and concentrates in bacterium solution, stirring while adding, after mixing and stirring, high pressure homogenize, pressure 14MPa, time 5min, is spray-dried, and sets feeding temperature 55 DEG C, feed rate 17L/min, inlet temperature 187 DEG C, leaving air temp 70 DEG C, cool, obtain laying hen finishing period Chinese medicine feed additive, by 6% basal diet adding laying hen to.
Embodiment 4
A kind of preparation method of laying hen finishing period Chinese medicine feed additive, comprise the following steps: one, Chinese medicine extract: weigh the Flos lonicerae 120 of following weight portion, Indigo Naturalis 120, Fructus Ligustri Lucidi 120, Herba Leonuri 120, Rhizoma Coptidis 100, Herba Chenopodii 100, Pericarpium Citri Reticulatae 100, Radix Sophorae Flavescentis 100, Fructus Crataegi (parched to brown) 80, the Radix Astragali 80, Radix Angelicae Sinensis 80, Hyodeoxycholic Acid 60, Radix Glycyrrhizae 40, by the ethanol solution of the 80% of each Study on Supermicro-pulverization of Traditional Chinese Drugs addition Chinese medicine gross weight 6 times amount, soak 60min, intense fire boils, slow fire insulation 30min, cools down Floor 12 filtered through gauze；Filtering residue adds the ethanol solution of the 70% of 5 times amount again, and intense fire boils, slow fire insulation 60min, cooling Floor 12 filtered through gauze, merges twice filtrate, concentration and recovery ethanol, concentrate without stopping during ethanol with in ethanol detector detection concentrated solution, add water in concentrated solution and make every milliliter of water crude drug Han 0.25g.White sugar 16Kg is added in units of 100 Kg concentrated solutions, and boil 3min, it is cooled to room temperature, inoculating lactobacillus, acetobacter xylinum and yeast (commercially available) preparation 23Kg, setting fermentation temperature 38 DEG C, standing for fermentation cultivates 120h, growing white truffle to pH6.5, cryoconcentration, makes every gram containing 0.5 gram of crude drug.Two, microcapsule is coated: weighs the microcapsule wall material modified starch 48 of following weight portion, arabic gum 18, beta-schardinger dextrin-18, syrup 28, adds purified water 430kg, adds Chinese medicine extract 108kg while stirring, after mixing and stirring, high pressure homogenize, pressure 16MPa Time 3-5min, is spray-dried, and sets feeding temperature 60 DEG C, feed rate 18L/min, inlet temperature 188 DEG C, leaving air temp 70 DEG C, cools, obtain laying hen finishing period Chinese medicine feed additive, by 7% basal diet adding laying hen to.
Embodiment 5
A kind of preparation method of laying hen finishing period Chinese medicine feed additive, comprise the following steps: one, Chinese medicine extract: weigh the Flos lonicerae 120 of following weight portion, Indigo Naturalis 120, Fructus Ligustri Lucidi 120, Herba Leonuri 120, Rhizoma Coptidis 100, Herba Chenopodii 100, Pericarpium Citri Reticulatae 100, Radix Sophorae Flavescentis 100, Fructus Crataegi (parched to brown) 80, the Radix Astragali 80, Radix Angelicae Sinensis 80, Hyodeoxycholic Acid 60, Radix Glycyrrhizae 40, by the ethanol solution of the 80% of each Study on Supermicro-pulverization of Traditional Chinese Drugs addition Chinese medicine gross weight 6 times amount, soak 60min, intense fire boils, slow fire insulation 60min, cools down Floor 12 filtered through gauze；Filtering residue adds the ethanol solution of the 60% of 6 times amount again, and intense fire boils, slow fire insulation 60min, cooling Floor 12 filtered through gauze, merges twice filtrate, concentration and recovery ethanol, concentrate without stopping during ethanol with in ethanol detector detection concentrated solution, add water in concentrated solution and make every milliliter of water crude drug Han 0.25g.White sugar 18Kg is added in units of 100 Kg concentrated solutions, and boil 4min, it is cooled to room temperature, inoculating lactobacillus, acetobacter xylinum and yeast (commercially available) preparation 24Kg, setting fermentation temperature 35 DEG C, standing for fermentation cultivates 96h, growing white truffle to pH5.5, cryoconcentration, makes every gram containing 0.5 gram of crude drug.Two, microcapsule is coated: weigh the microcapsule wall material modified starch 49 of following weight portion, arabic gum 19, beta-schardinger dextrin-19, syrup 29, joins 450kg and concentrates in bacterium solution, stirring while adding, after mixing and stirring, high pressure homogenize, pressure 18MPa, time 4min, is spray-dried, and sets feeding temperature 60 DEG C, feed rate 20L/min, inlet temperature 189 DEG C, leaving air temp 68 DEG C, cool, obtain laying hen finishing period Chinese medicine feed additive, add in laying hens essential ration by 8%.
Embodiment 6
A kind of preparation method of laying hen finishing period Chinese medicine feed additive, comprise the following steps: one, Chinese medicine extract: weigh the Flos lonicerae 120 of following weight portion, Indigo Naturalis 120, Fructus Ligustri Lucidi 120, Herba Leonuri 120, Rhizoma Coptidis 100, Herba Chenopodii 100, Pericarpium Citri Reticulatae 100, Radix Sophorae Flavescentis 100, Fructus Crataegi (parched to brown) 80, the Radix Astragali 80, Radix Angelicae Sinensis 80, Hyodeoxycholic Acid 60, Radix Glycyrrhizae 40, by the ethanol solution of the 80% of each Study on Supermicro-pulverization of Traditional Chinese Drugs addition Chinese medicine gross weight 6 times amount, soak 60min, intense fire boils, slow fire insulation 30min, cools down Floor 12 filtered through gauze；Filtering residue adds the ethanol solution of the 70% of 6 times amount again, and intense fire boils, slow fire insulation 60min, cooling Floor 12 filtered through gauze, merges twice filtrate, concentration and recovery ethanol, concentrate without stopping during ethanol with in ethanol detector detection concentrated solution, add water in concentrated solution and make every milliliter of water crude drug Han 0.25g.White sugar 20Kg is added in units of 100 Kg concentrated solutions, and boil 5min, it is cooled to room temperature, inoculating lactobacillus, acetobacter xylinum and yeast (commercially available) preparation 25Kg, setting fermentation temperature 36 DEG C, standing for fermentation cultivates 96h, growing white truffle to pH6.0, cryoconcentration, makes every gram containing 0.5 gram of crude drug.Two, microcapsule is coated: weigh the microcapsule wall material modified starch 50 of following weight portion, arabic gum 20, beta-schardinger dextrin-20, syrup 30, joins 460kg and concentrates in bacterium solution, stirring while adding, after mixing and stirring, high pressure homogenize, pressure 20MPa, time 5min, is spray-dried, and sets feeding temperature 60 DEG C, feed rate 20L/min, inlet temperature 190 DEG C, leaving air temp 70 DEG C, cool, obtain laying hen finishing period Chinese medicine feed additive, add in laying hens essential ration by 4%.
Embodiment 7
A kind of preparation method of laying hen finishing period Chinese medicine feed additive, comprise the following steps: one, Chinese medicine extract: weigh the Flos lonicerae 120 of following weight portion, Indigo Naturalis 120, Fructus Ligustri Lucidi 120, Herba Leonuri 120, Rhizoma Coptidis 100, Herba Chenopodii 100, Pericarpium Citri Reticulatae 100, Radix Sophorae Flavescentis 100, Fructus Crataegi (parched to brown) 80, the Radix Astragali 80, Radix Angelicae Sinensis 80, Hyodeoxycholic Acid 60, Radix Glycyrrhizae 40, by the ethanol solution of the 90% of each Study on Supermicro-pulverization of Traditional Chinese Drugs addition Chinese medicine gross weight 8 times amount, soak 60min, intense fire boils, slow fire insulation 30min, cools down Floor 12 filtered through gauze；Filtering residue adds the ethanol solution of the 60% of 4 times amount again, and intense fire boils, slow fire insulation 60min, cooling Floor 12 filtered through gauze, merges twice filtrate, concentration and recovery ethanol, concentrate without stopping during ethanol with in ethanol detector detection concentrated solution, add water in concentrated solution and make every milliliter of water crude drug Han 0.25g.White sugar 12Kg is added in units of 100 Kg concentrated solutions, and boil 3min, it is cooled to room temperature, inoculating lactobacillus, acetobacter xylinum and yeast (commercially available) preparation 20Kg, setting fermentation temperature 37 DEG C, standing for fermentation cultivates 108h, growing white truffle to pH6.5, cryoconcentration, makes every gram containing 0.5 gram of crude drug.Two, microcapsule is coated: weigh the microcapsule wall material modified starch 51 of following weight portion, arabic gum 15, beta-schardinger dextrin-15, syrup 25, joins 470kg and concentrates in bacterium solution, stirring while adding, after mixing and stirring, high pressure homogenize, pressure 10MPa, time 3min, is spray-dried, and sets feeding temperature 50 DEG C, feed rate 15L/min, inlet temperature 185 DEG C, leaving air temp 60 DEG C, cool, obtain laying hen finishing period Chinese medicine feed additive, add in laying hens essential ration by 5%.
Embodiment 8
A kind of preparation method of laying hen finishing period Chinese medicine feed additive, comprise the following steps: one, Chinese medicine extract: weigh the Flos lonicerae 120 of following weight portion, Indigo Naturalis 120, Fructus Ligustri Lucidi 120, Herba Leonuri 120, Rhizoma Coptidis 100, Herba Chenopodii 100, Pericarpium Citri Reticulatae 100, Radix Sophorae Flavescentis 100, Fructus Crataegi (parched to brown) 80, the Radix Astragali 80, Radix Angelicae Sinensis 80, Hyodeoxycholic Acid 60, Radix Glycyrrhizae 40, by the ethanol solution of the 90% of each Study on Supermicro-pulverization of Traditional Chinese Drugs addition Chinese medicine gross weight 8 times amount, soak 60min, intense fire boils, slow fire insulation 30min, cools down Floor 12 filtered through gauze；Filtering residue adds the ethanol solution of the 70% of 4 times amount again, and intense fire boils, slow fire insulation 60min, cooling Floor 12 filtered through gauze, merges twice filtrate, concentration and recovery ethanol, concentrate without stopping during ethanol with in ethanol detector detection concentrated solution, add water in concentrated solution and make every milliliter of water crude drug Han 0.25g.White sugar 14Kg is added in units of 100 Kg concentrated solutions, and boil 4min, it is cooled to room temperature, inoculating lactobacillus, acetobacter xylinum and yeast (commercially available) preparation 20Kg, setting fermentation temperature 38 DEG C, standing for fermentation cultivates 120h, growing white truffle to pH6.5, cryoconcentration, makes every gram containing 0.5 gram of crude drug.Two, microcapsule is coated: weigh the microcapsule wall material modified starch 52 of following weight portion, arabic gum 16, beta-schardinger dextrin-15-20, syrup 26, join 480kg and concentrate in bacterium solution, stirring while adding, after mixing and stirring, high pressure homogenize, pressure 18MPa, time 4min, is spray-dried, and sets feeding temperature 54 DEG C, feed rate 16L/min, inlet temperature 186 DEG C, leaving air temp 62 DEG C, cool, obtain laying hen finishing period Chinese medicine feed additive, by 6% basal diet adding laying hen to.
Embodiment 9
A kind of preparation method of laying hen finishing period Chinese medicine feed additive, comprise the following steps: one, Chinese medicine extract: weigh the Flos lonicerae 120 of following weight portion, Indigo Naturalis 120, Fructus Ligustri Lucidi 120, Herba Leonuri 120, Rhizoma Coptidis 100, Herba Chenopodii 100, Pericarpium Citri Reticulatae 100, Radix Sophorae Flavescentis 100, Fructus Crataegi (parched to brown) 80, the Radix Astragali 80, Radix Angelicae Sinensis 80, Hyodeoxycholic Acid 60, Radix Glycyrrhizae 40, by the ethanol solution of the 90% of each Study on Supermicro-pulverization of Traditional Chinese Drugs addition Chinese medicine gross weight 8 times amount, soak 60min, intense fire boils, slow fire insulation 60min, cools down Floor 12 filtered through gauze；Filtering residue adds the ethanol solution of the 60% of 5 times amount again, and intense fire boils, slow fire insulation 30min, cooling Floor 12 filtered through gauze, merges twice filtrate, concentration and recovery ethanol, concentrate without stopping during ethanol with in ethanol detector detection concentrated solution, add water in concentrated solution and make every milliliter of water crude drug Han 0.25g.White sugar 16Kg is added in units of 100 Kg concentrated solutions, and boil 5min, it is cooled to room temperature, inoculating lactobacillus, acetobacter xylinum and yeast (commercially available) preparation 22Kg, setting fermentation temperature 35 DEG C, standing for fermentation cultivates 96h, growing white truffle to pH5.5, cryoconcentration, makes every gram containing 0.5 gram of crude drug.Two, microcapsule is coated: weigh the microcapsule wall material modified starch 53 of following weight portion, arabic gum 17, beta-schardinger dextrin-17, syrup 27, joins 490kg and concentrates in bacterium solution, stirring while adding, after mixing and stirring, high pressure homogenize, pressure 20MPa, time 5min, is spray-dried, and sets feeding temperature 60 DEG C, feed rate 120L/min, inlet temperature 190 DEG C, leaving air temp 70 DEG C, cool, obtain laying hen finishing period Chinese medicine feed additive, add in laying hens essential ration by 7%.
Embodiment 10
A kind of preparation method of laying hen finishing period Chinese medicine feed additive, comprise the following steps: one, Chinese medicine extract: weigh the Flos lonicerae 120 of following weight portion, Indigo Naturalis 120, Fructus Ligustri Lucidi 120, Herba Leonuri 120, Rhizoma Coptidis 100, Herba Chenopodii 100, Pericarpium Citri Reticulatae 100, Radix Sophorae Flavescentis 100, Fructus Crataegi (parched to brown) 80, the Radix Astragali 80, Radix Angelicae Sinensis 80, Hyodeoxycholic Acid 60, Radix Glycyrrhizae 40, by the ethanol solution of the 90% of each Study on Supermicro-pulverization of Traditional Chinese Drugs addition Chinese medicine gross weight 8 times amount, soak 30min, intense fire boils, slow fire insulation 60min, cools down Floor 12 filtered through gauze；Filtering residue adds the ethanol solution of the 70% of 5 times amount again, and intense fire boils 60min, cools down Floor 12 filtered through gauze, merge twice filtrate, concentration and recovery ethanol, concentrates without stopping during ethanol with in ethanol detector detection concentrated solution, adds water and make every milliliter of water crude drug Han 0.25g in concentrated solution.White sugar 16Kg is added in units of 100 Kg concentrated solutions, and boil 3min, it is cooled to room temperature, inoculating lactobacillus, acetobacter xylinum and yeast (commercially available) preparation 23Kg, setting fermentation temperature 36 DEG C, standing for fermentation cultivates 120h, growing white truffle to pH6.5, cryoconcentration, makes every gram containing 0.5 gram of crude drug.Two, microcapsule is coated: weigh the microcapsule wall material modified starch 55 of following weight portion, arabic gum 18, beta-schardinger dextrin-18, syrup 27, joins 490kg and concentrates in bacterium solution, stirring while adding, after mixing and stirring, high pressure homogenize, pressure 14MPa, time 3min, is spray-dried, and sets feeding temperature 60 DEG C, feed rate 20L/min, inlet temperature 190 DEG C, leaving air temp 70 DEG C, cool, obtain laying hen finishing period Chinese medicine feed additive, add in laying hens essential ration by 8%.
Embodiment 11
A kind of preparation method of laying hen finishing period Chinese medicine feed additive, comprise the following steps: one, Chinese medicine extract: weigh the Flos lonicerae 120 of following weight portion, Indigo Naturalis 120, Fructus Ligustri Lucidi 120, Herba Leonuri 120, Rhizoma Coptidis 100, Herba Chenopodii 100, Pericarpium Citri Reticulatae 100, Radix Sophorae Flavescentis 100, Fructus Crataegi (parched to brown) 80, the Radix Astragali 80, Radix Angelicae Sinensis 80, Hyodeoxycholic Acid 60, Radix Glycyrrhizae 40, by the ethanol solution of the 90% of each Study on Supermicro-pulverization of Traditional Chinese Drugs addition Chinese medicine gross weight 8 times amount, soak 360min, intense fire boils, slow fire insulation 60min, cools down Floor 12 filtered through gauze；Filtering residue adds the ethanol solution of the 60% of 6 times amount again, and intense fire boils, slow fire insulation 30min, cooling Floor 12 filtered through gauze, merges twice filtrate, concentration and recovery ethanol, concentrate without stopping during ethanol with in ethanol detector detection concentrated solution, add water in concentrated solution and make every milliliter of water crude drug Han 0.25g.White sugar 18Kg is added in units of 100 Kg concentrated solutions, and boil 4min, it is cooled to room temperature, inoculating lactobacillus, acetobacter xylinum and yeast (commercially available) preparation 24Kg, setting fermentation temperature 37 DEG C, standing for fermentation cultivates 1080h, growing white truffle to pH6.0, cryoconcentration, makes every gram containing 0.5 gram of crude drug.Two, microcapsule is coated: weigh the microcapsule wall material modified starch 55 of following weight portion, arabic gum 20, beta-schardinger dextrin-20, syrup 30, joins 500kg and concentrates in bacterium solution, stirring while adding, after mixing and stirring, high pressure homogenize, pressure 20MPa, time 4min, is spray-dried, and sets feeding temperature 60 DEG C, feed rate 19L/min, inlet temperature 186 DEG C, leaving air temp 70 DEG C, cool, obtain laying hen finishing period Chinese medicine feed additive, add in laying hens essential ration by 4%.
Embodiment 12
A kind of preparation method of laying hen finishing period Chinese medicine feed additive, comprise the following steps: one, Chinese medicine extract: weigh the Flos lonicerae 120 of following weight portion, Indigo Naturalis 120, Fructus Ligustri Lucidi 120, Herba Leonuri 120, Rhizoma Coptidis 100, Herba Chenopodii 100, Pericarpium Citri Reticulatae 100, Radix Sophorae Flavescentis 100, Fructus Crataegi (parched to brown) 80, the Radix Astragali 80, Radix Angelicae Sinensis 80, Hyodeoxycholic Acid 60, Radix Glycyrrhizae 40, by the ethanol solution of the 90% of each Study on Supermicro-pulverization of Traditional Chinese Drugs addition Chinese medicine gross weight 8 times amount, soak 30min, intense fire boils, slow fire insulation 60min, cools down Floor 12 filtered through gauze；Filtering residue adds the ethanol solution of the 70% of 6 times amount again, and intense fire boils, slow fire insulation 60min, cooling Floor 12 filtered through gauze, merges twice filtrate, concentration and recovery ethanol, concentrate without stopping during ethanol with in ethanol detector detection concentrated solution, add water in concentrated solution and make every milliliter of water crude drug Han 0.25g.White sugar 20Kg is added in units of 100 Kg concentrated solutions, and boil 5min, it is cooled to room temperature, inoculating lactobacillus, acetobacter xylinum and yeast (commercially available) preparation 25Kg, setting fermentation temperature 38 DEG C, standing for fermentation cultivates 96h, growing white truffle to pH6.5, cryoconcentration, makes every gram containing 0.5 gram of crude drug.Two, microcapsule is coated: weigh the microcapsule wall material modified starch 55 of following weight portion, arabic gum 20, beta-schardinger dextrin-20, syrup 30, joins 400kg and concentrates in bacterium solution, stirring while adding, after mixing and stirring, high pressure homogenize, pressure 20MPa, time 3min, is spray-dried, and sets feeding temperature 60 DEG C, feed rate 20L/min, inlet temperature 190 DEG C, leaving air temp 70 DEG C, cool, obtain laying hen finishing period Chinese medicine feed additive, add in laying hens essential ration by 5%.
Embodiment 13
A kind of preparation method of laying hen finishing period Chinese medicine feed additive, comprise the following steps: one, Chinese medicine extract: weigh the Flos lonicerae 140 of following weight portion, Indigo Naturalis 140, Fructus Ligustri Lucidi 140, Herba Leonuri 140, Rhizoma Coptidis 120, Herba Chenopodii 120, Pericarpium Citri Reticulatae 120, Radix Sophorae Flavescentis 120, Fructus Crataegi (parched to brown) 100, the Radix Astragali 100, Radix Angelicae Sinensis 100, Hyodeoxycholic Acid 80, Radix Glycyrrhizae 60, by the ethanol solution of the 80% of each Study on Supermicro-pulverization of Traditional Chinese Drugs addition Chinese medicine gross weight 6 times amount, soak 30min, intense fire boils, slow fire insulation 30min, cools down Floor 12 filtered through gauze；Filtering residue adds the ethanol solution of the 60% of 4 times amount again, and intense fire boils, slow fire insulation 30min, cooling Floor 12 filtered through gauze, merges twice filtrate, concentration and recovery ethanol, concentrate without stopping during ethanol with in ethanol detector detection concentrated solution, add water in concentrated solution and make every milliliter of water crude drug Han 0.25g.White sugar 10Kg is added in units of 100 Kg concentrated solutions, and boil 3min, it is cooled to room temperature, inoculating lactobacillus, acetobacter xylinum and yeast (commercially available) preparation 20Kg, setting fermentation temperature 35 DEG C, standing for fermentation cultivates 96h, growing white truffle to pH5.5, cryoconcentration, makes every gram containing 0.5 gram of crude drug.Two, microcapsule is coated: weigh the microcapsule wall material modified starch 45 of following weight portion, arabic gum 15, beta-schardinger dextrin-15, syrup 25, joins 410kg and concentrates in bacterium solution, stirring while adding, after mixing and stirring, high pressure homogenize, pressure 10MPa, time 3min, is spray-dried, and sets feeding temperature 50 DEG C, feed rate 15L/min, inlet temperature 185 DEG C, leaving air temp 60 DEG C, cool, obtain laying hen finishing period Chinese medicine feed additive, add in laying hens essential ration by 6%.
Embodiment 14
A kind of preparation method of laying hen finishing period Chinese medicine feed additive, comprise the following steps: one, Chinese medicine extract: weigh the Flos lonicerae 140 of following weight portion, Indigo Naturalis 140, Fructus Ligustri Lucidi 140, Herba Leonuri 140, Rhizoma Coptidis 120, Herba Chenopodii 120, Pericarpium Citri Reticulatae 120, Radix Sophorae Flavescentis 120, Fructus Crataegi (parched to brown) 100, the Radix Astragali 100, Radix Angelicae Sinensis 100, Hyodeoxycholic Acid 80, Radix Glycyrrhizae 60, by the ethanol solution of the 80% of each Study on Supermicro-pulverization of Traditional Chinese Drugs addition Chinese medicine gross weight 6 times amount, soak 60min, intense fire boils, slow fire insulation 60min, cools down Floor 12 filtered through gauze；Filtering residue adds the ethanol solution of the 70% of 4 times amount again, and intense fire boils, slow fire insulation 60min, cooling Floor 12 filtered through gauze, merges twice filtrate, concentration and recovery ethanol, concentrate without stopping during ethanol with in ethanol detector detection concentrated solution, add water in concentrated solution and make every milliliter of water crude drug Han 0.25g.White sugar 12Kg is added in units of 100 Kg concentrated solutions, and boil 4min, it is cooled to room temperature, inoculating lactobacillus, acetobacter xylinum and yeast (commercially available) preparation 21Kg, setting fermentation temperature 36 DEG C, standing for fermentation cultivates 110h, growing white truffle to pH6.0, cryoconcentration, makes every gram containing 0.5 gram of crude drug.Two, microcapsule is coated: weigh the microcapsule wall material modified starch 46 of following weight portion, arabic gum 16, beta-schardinger dextrin-16, syrup 26, joins 420kg and concentrates in bacterium solution, stirring while adding, after mixing and stirring, high pressure homogenize, pressure 12MPa, time 4min, is spray-dried, and sets feeding temperature 52 DEG C, feed rate 16L/min, inlet temperature 186 DEG C, leaving air temp 62 DEG C, cool, obtain laying hen finishing period Chinese medicine feed additive, add in laying hens essential ration by 7%.
Embodiment 15
A kind of preparation method of laying hen finishing period Chinese medicine feed additive, comprise the following steps: one, Chinese medicine extract: weigh the Flos lonicerae 140 of following weight portion, Indigo Naturalis 140, Fructus Ligustri Lucidi 140, Herba Leonuri 140, Rhizoma Coptidis 120, Herba Chenopodii 120, Pericarpium Citri Reticulatae 120, Radix Sophorae Flavescentis 120, Fructus Crataegi (parched to brown) 100, the Radix Astragali 100, Radix Angelicae Sinensis 100, Hyodeoxycholic Acid 80, Radix Glycyrrhizae 60, by the ethanol solution of the 80% of each Study on Supermicro-pulverization of Traditional Chinese Drugs addition Chinese medicine gross weight 6 times amount, soak 30min, intense fire boils, slow fire insulation 60min, cools down Floor 12 filtered through gauze；Filtering residue adds the ethanol solution of the 60% of 5 times amount again, and intense fire boils, slow fire insulation 60min, cooling Floor 12 filtered through gauze, merges twice filtrate, concentration and recovery ethanol, concentrate without stopping during ethanol with in ethanol detector detection concentrated solution, add water in concentrated solution and make every milliliter of water crude drug Han 0.25g.White sugar 14Kg is added in units of 100 Kg concentrated solutions, and boil 5min, it is cooled to room temperature, inoculating lactobacillus, acetobacter xylinum and yeast (commercially available) preparation 22Kg, setting fermentation temperature 37 DEG C, standing for fermentation cultivates 120h, growing white truffle to pH6.5, cryoconcentration, makes every gram containing 0.5 gram of crude drug.Two, microcapsule is coated: weigh the microcapsule wall material modified starch 47 of following weight portion, arabic gum 17, beta-schardinger dextrin-17, syrup 27, joins 430kg and concentrates in bacterium solution, stirring while adding, after mixing and stirring, high pressure homogenize, pressure 14MPa, time 5min, is spray-dried, and sets feeding temperature 54 DEG C, feed rate 17L/min, inlet temperature 187 DEG C, leaving air temp 64 DEG C, cool, obtain laying hen finishing period Chinese medicine feed additive, add in laying hens essential ration by 8%.
Embodiment 16
A kind of preparation method of laying hen finishing period Chinese medicine feed additive, comprise the following steps: one, Chinese medicine extract: weigh the Flos lonicerae 140 of following weight portion, Indigo Naturalis 140, Fructus Ligustri Lucidi 140, Herba Leonuri 140, Rhizoma Coptidis 120, Herba Chenopodii 120, Pericarpium Citri Reticulatae 120, Radix Sophorae Flavescentis 120, Fructus Crataegi (parched to brown) 100, the Radix Astragali 100, Radix Angelicae Sinensis 100, Hyodeoxycholic Acid 80, Radix Glycyrrhizae 60, by the ethanol solution of the 80% of each Study on Supermicro-pulverization of Traditional Chinese Drugs addition Chinese medicine gross weight 6 times amount, soak 60min, intense fire boils, slow fire insulation 30min, cools down Floor 12 filtered through gauze；Filtering residue adds the ethanol solution of the 70% of 5 times amount again, and intense fire boils, slow fire insulation 60min, cooling Floor 12 filtered through gauze, merges twice filtrate, concentration and recovery ethanol, concentrate without stopping during ethanol with in ethanol detector detection concentrated solution, add water in concentrated solution and make every milliliter of water crude drug Han 0.25g.White sugar 16Kg is added in units of 100 Kg concentrated solutions, and boil 3min, it is cooled to room temperature, inoculating lactobacillus, acetobacter xylinum and yeast (commercially available) preparation 23Kg, setting fermentation temperature 38 DEG C, standing for fermentation cultivates 96h, growing white truffle to pH5.5, cryoconcentration, makes every gram containing 0.5 gram of crude drug.Two, microcapsule is coated: weigh the microcapsule wall material modified starch 48 of following weight portion, arabic gum 18, beta-schardinger dextrin-18, syrup 28, joins 450kg and concentrates in bacterium solution, stirring while adding, after mixing and stirring, high pressure homogenize, pressure 16MPa, time 4min, is spray-dried, and sets feeding temperature 56 DEG C, feed rate 18L/min, inlet temperature 188 DEG C, leaving air temp 60 DEG C, cool, obtain laying hen finishing period Chinese medicine feed additive, add in laying hens essential ration by 4%.
Embodiment 17
A kind of preparation method of laying hen finishing period Chinese medicine feed additive, comprise the following steps: one, Chinese medicine extract: weigh the Flos lonicerae 140 of following weight portion, Indigo Naturalis 140, Fructus Ligustri Lucidi 140, Herba Leonuri 140, Rhizoma Coptidis 120, Herba Chenopodii 120, Pericarpium Citri Reticulatae 120, Radix Sophorae Flavescentis 120, Fructus Crataegi (parched to brown) 100, the Radix Astragali 100, Radix Angelicae Sinensis 100, Hyodeoxycholic Acid 80, Radix Glycyrrhizae 60, by the ethanol solution of the 80% of each Study on Supermicro-pulverization of Traditional Chinese Drugs addition Chinese medicine gross weight 6 times amount, soak 60min, intense fire boils, slow fire insulation 60min, cools down Floor 12 filtered through gauze；Filtering residue adds the ethanol solution of the 60% of 6 times amount again, and intense fire boils, slow fire insulation 60min, cooling Floor 12 filtered through gauze, merges twice filtrate, concentration and recovery ethanol, concentrate without stopping during ethanol with in ethanol detector detection concentrated solution, add water in concentrated solution and make every milliliter of water crude drug Han 0.25g.White sugar 18Kg is added in units of 100 Kg concentrated solutions, and boil 4min, it is cooled to room temperature, inoculating lactobacillus, acetobacter xylinum and yeast (commercially available) preparation 24Kg, setting fermentation temperature 35 DEG C, standing for fermentation cultivates 120h, growing white truffle to pH6.5, cryoconcentration, makes every gram containing 0.5 gram of crude drug.Two, microcapsule is coated: weigh the microcapsule wall material modified starch 49 of following weight portion, arabic gum 19, beta-schardinger dextrin-19, syrup 29, joins 460kg and concentrates in bacterium solution, stirring while adding, after mixing and stirring, high pressure homogenize, pressure 18MPa, time 4min, is spray-dried, and sets feeding temperature 60 DEG C, feed rate 20L/min, inlet temperature 190 DEG C, leaving air temp 70 DEG C, cool, obtain laying hen finishing period Chinese medicine feed additive, add in laying hens essential ration by 5%.
Embodiment 18
A kind of preparation method of laying hen finishing period Chinese medicine feed additive, comprise the following steps: one, Chinese medicine extract: weigh the Flos lonicerae 140 of following weight portion, Indigo Naturalis 140, Fructus Ligustri Lucidi 140, Herba Leonuri 140, Rhizoma Coptidis 120, Herba Chenopodii 120, Pericarpium Citri Reticulatae 120, Radix Sophorae Flavescentis 120, Fructus Crataegi (parched to brown) 100, the Radix Astragali 100, Radix Angelicae Sinensis 100, Hyodeoxycholic Acid 80, Radix Glycyrrhizae 60, by the ethanol solution of the 80% of each Study on Supermicro-pulverization of Traditional Chinese Drugs addition Chinese medicine gross weight 6 times amount, soak 30min, intense fire boils, slow fire insulation 60min, cools down Floor 12 filtered through gauze；Filtering residue adds the ethanol solution of the 70% of 6 times amount again, and intense fire boils, slow fire insulation 30min, cooling Floor 12 filtered through gauze, merges twice filtrate, concentration and recovery ethanol, concentrate without stopping during ethanol with in ethanol detector detection concentrated solution, add water in concentrated solution and make every milliliter of water crude drug Han 0.25g.White sugar 20Kg is added in units of 100 Kg concentrated solutions, and boil 5min, it is cooled to room temperature, inoculating lactobacillus, acetobacter xylinum and yeast (commercially available) preparation 25Kg, setting fermentation temperature 38 DEG C, standing for fermentation cultivates 108h, growing white truffle to pH6.0, cryoconcentration, makes every gram containing 0.5 gram of crude drug.Two, microcapsule is coated: weigh the microcapsule wall material modified starch 50 of following weight portion, arabic gum 20, beta-schardinger dextrin-20, syrup 30, joins 470kg and concentrates in bacterium solution, stirring while adding, after mixing and stirring, high pressure homogenize, pressure 20MPa, time 5min, is spray-dried, and sets feeding temperature 60 DEG C, feed rate 20L/min, inlet temperature 190 DEG C, leaving air temp 70 DEG C, cool, obtain laying hen finishing period Chinese medicine feed additive, add in laying hens essential ration by 6%.
Embodiment 19
A kind of preparation method of laying hen finishing period Chinese medicine feed additive, comprise the following steps: one, Chinese medicine extract: weigh the Flos lonicerae 140 of following weight portion, Indigo Naturalis 140, Fructus Ligustri Lucidi 140, Herba Leonuri 140, Rhizoma Coptidis 120, Herba Chenopodii 120, Pericarpium Citri Reticulatae 120, Radix Sophorae Flavescentis 120, Fructus Crataegi (parched to brown) 100, the Radix Astragali 100, Radix Angelicae Sinensis 100, Hyodeoxycholic Acid 80, Radix Glycyrrhizae 60, by the ethanol solution of the 90% of each Study on Supermicro-pulverization of Traditional Chinese Drugs addition Chinese medicine gross weight 8 times amount, soak 60min, intense fire boils, slow fire insulation 30min, cools down Floor 12 filtered through gauze；Filtering residue adds the ethanol solution of the 60% of 4 times amount again, and intense fire boils, slow fire insulation 60min, cooling Floor 12 filtered through gauze, merges twice filtrate, concentration and recovery ethanol, concentrate without stopping during ethanol with in ethanol detector detection concentrated solution, add water in concentrated solution and make every milliliter of water crude drug Han 0.25g.White sugar 10Kg is added in units of 100 Kg concentrated solutions, and boil 3min, it is cooled to room temperature, inoculating lactobacillus, acetobacter xylinum and yeast (commercially available) preparation 20Kg, setting fermentation temperature 35 DEG C, standing for fermentation cultivates 120h, growing white truffle to pH6.5, cryoconcentration, makes every gram containing 0.5 gram of crude drug.Two, microcapsule is coated: weigh the microcapsule wall material modified starch 54 of following weight portion, arabic gum 15, beta-schardinger dextrin-15, syrup 25, joins 480kg and concentrates in bacterium solution, stirring while adding, after mixing and stirring, high pressure homogenize, pressure 10MPa, time 5min, is spray-dried, and sets feeding temperature 60 DEG C, feed rate 20L/min, inlet temperature 190 DEG C, leaving air temp 70 DEG C, cool, obtain laying hen finishing period Chinese medicine feed additive, add in laying hens essential ration by 7%.
Embodiment 20
A kind of preparation method of laying hen finishing period Chinese medicine feed additive, comprise the following steps: one, Chinese medicine extract: weigh the Flos lonicerae 140 of following weight portion, Indigo Naturalis 140, Fructus Ligustri Lucidi 140, Herba Leonuri 140, Rhizoma Coptidis 120, Herba Chenopodii 120, Pericarpium Citri Reticulatae 120, Radix Sophorae Flavescentis 120, Fructus Crataegi (parched to brown) 100, the Radix Astragali 100, Radix Angelicae Sinensis 100, Hyodeoxycholic Acid 80, Radix Glycyrrhizae 60, by the ethanol solution of the 90% of each Study on Supermicro-pulverization of Traditional Chinese Drugs addition Chinese medicine gross weight 8 times amount, soak 30min, intense fire boils, slow fire insulation 30min, cools down Floor 12 filtered through gauze；Filtering residue adds the ethanol solution of the 70% of 4 times amount again, and intense fire boils, slow fire insulation 60min, cooling Floor 12 filtered through gauze, merges twice filtrate, concentration and recovery ethanol, concentrate without stopping during ethanol with in ethanol detector detection concentrated solution, add water in concentrated solution and make every milliliter of water crude drug Han 0.25g.White sugar 12Kg is added in units of 100 Kg concentrated solutions, and boil 3min, it is cooled to room temperature, inoculating lactobacillus, acetobacter xylinum and yeast (commercially available) preparation 22Kg, setting fermentation temperature 38 DEG C, standing for fermentation cultivates 96h, growing white truffle to pH5.5, cryoconcentration, makes every gram containing 0.5 gram of crude drug.Two, microcapsule is coated: weigh the microcapsule wall material modified starch 52 of following weight portion, arabic gum 17, beta-schardinger dextrin-17, syrup 27, joins 480kg and concentrates in bacterium solution, stirring while adding, after mixing and stirring, high pressure homogenize, pressure 14MPa, time 5min, is spray-dried, and sets feeding temperature 50 DEG C, feed rate 15L/min, inlet temperature 185 DEG C, leaving air temp 60 DEG C, cool, obtain laying hen finishing period Chinese medicine feed additive, add in laying hens essential ration by 8%.
Embodiment 21
A kind of preparation method of laying hen finishing period Chinese medicine feed additive, comprise the following steps: one, Chinese medicine extract: weigh the Flos lonicerae 140 of following weight portion, Indigo Naturalis 140, Fructus Ligustri Lucidi 140, Herba Leonuri 140, Rhizoma Coptidis 120, Herba Chenopodii 120, Pericarpium Citri Reticulatae 120, Radix Sophorae Flavescentis 120, Fructus Crataegi (parched to brown) 100, the Radix Astragali 100, Radix Angelicae Sinensis 100, Hyodeoxycholic Acid 80, Radix Glycyrrhizae 60, by the ethanol solution of the 90% of each Study on Supermicro-pulverization of Traditional Chinese Drugs addition Chinese medicine gross weight 8 times amount, soak 30min, intense fire boils, slow fire insulation 30min, cools down Floor 12 filtered through gauze；Filtering residue adds the ethanol solution of the 60% of 5 times amount again, and intense fire boils, slow fire insulation 30min, cooling Floor 12 filtered through gauze, merges twice filtrate, concentration and recovery ethanol, concentrate without stopping during ethanol with in ethanol detector detection concentrated solution, add water in concentrated solution and make every milliliter of water crude drug Han 0.25g.White sugar 16Kg is added in units of 100 Kg concentrated solutions, and boil 5min, it is cooled to room temperature, inoculating lactobacillus, acetobacter xylinum and yeast (commercially available) preparation 23Kg, setting fermentation temperature 35 DEG C, standing for fermentation cultivates 118h, growing white truffle to pH6.5, cryoconcentration, makes every gram containing 0.5 gram of crude drug.Two, microcapsule is coated: weigh the microcapsule wall material modified starch 53 of following weight portion, arabic gum 18, beta-schardinger dextrin-18, syrup 28, joins 490kg and concentrates in bacterium solution, stirring while adding, after mixing and stirring, high pressure homogenize, pressure 20MPa, time 3min, is spray-dried, and sets feeding temperature 60 DEG C, feed rate 20L/min, inlet temperature 190 DEG C, leaving air temp 70 DEG C, cool, obtain laying hen finishing period Chinese medicine feed additive, add in laying hens essential ration by 4%.
Embodiment 22
A kind of preparation method of laying hen finishing period Chinese medicine feed additive, comprise the following steps: one, Chinese medicine extract: weigh the Flos lonicerae 140 of following weight portion, Indigo Naturalis 140, Fructus Ligustri Lucidi 140, Herba Leonuri 140, Rhizoma Coptidis 120, Herba Chenopodii 120, Pericarpium Citri Reticulatae 120, Radix Sophorae Flavescentis 120, Fructus Crataegi (parched to brown) 100, the Radix Astragali 100, Radix Angelicae Sinensis 100, Hyodeoxycholic Acid 80, Radix Glycyrrhizae 60, by the ethanol solution of the 90% of each Study on Supermicro-pulverization of Traditional Chinese Drugs addition Chinese medicine gross weight 8 times amount, soak 30min, intense fire boils, slow fire insulation 60min, cools down Floor 12 filtered through gauze；Filtering residue adds the ethanol solution of the 70% of 5 times amount again, and intense fire boils, slow fire insulation 60min, cooling Floor 12 filtered through gauze, merges twice filtrate, concentration and recovery ethanol, concentrate without stopping during ethanol with in ethanol detector detection concentrated solution, add water in concentrated solution and make every milliliter of water crude drug Han 0.25g.White sugar 16Kg is added in units of 100 Kg concentrated solutions, and boil 3min, it is cooled to room temperature, inoculating lactobacillus, acetobacter xylinum and yeast (commercially available) preparation 23Kg, setting fermentation temperature 36 DEG C, standing for fermentation cultivates 110h, growing white truffle to pH6.0, cryoconcentration, makes every gram containing 0.5 gram of crude drug.Two, microcapsule is coated: weigh the microcapsule wall material modified starch 55 of following weight portion, arabic gum 18, beta-schardinger dextrin-18, syrup 28, joins 500kg and concentrates in bacterium solution, stirring while adding, after mixing and stirring, high pressure homogenize, pressure 20MPa, time 3min, is spray-dried, and sets feeding temperature 60 DEG C, feed rate 20L/min, inlet temperature 190 DEG C, leaving air temp 70 DEG C, cool, obtain laying hen finishing period Chinese medicine feed additive, add in laying hens essential ration by 5%.
Embodiment 23
A kind of preparation method of laying hen finishing period Chinese medicine feed additive, comprise the following steps: one, Chinese medicine extract: weigh the Chinese medicine Flos lonicerae 140 of following weight portion, Indigo Naturalis 140, Fructus Ligustri Lucidi 140, Herba Leonuri 140, Rhizoma Coptidis 120, Herba Chenopodii 120, Pericarpium Citri Reticulatae 120, Radix Sophorae Flavescentis 120, Fructus Crataegi (parched to brown) 100, the Radix Astragali 100, Radix Angelicae Sinensis 100, Hyodeoxycholic Acid 80, Radix Glycyrrhizae 60, by the ethanol solution of the 90% of each Study on Supermicro-pulverization of Traditional Chinese Drugs addition Chinese medicine gross weight 8 times amount, soak 30min, intense fire boils, slow fire insulation 60min, cools down Floor 12 filtered through gauze；Filtering residue adds the ethanol solution of the 60% of 6 times amount again, and intense fire boils, slow fire insulation 60min, cooling Floor 12 filtered through gauze, merges twice filtrate, concentration and recovery ethanol, concentrate without stopping during ethanol with in ethanol detector detection concentrated solution, add water in concentrated solution and make every milliliter of water crude drug Han 0.25g.White sugar 18Kg is added in units of 100 Kg concentrated solutions, and boil 4min, it is cooled to room temperature, inoculating lactobacillus, acetobacter xylinum and yeast (commercially available) preparation 24Kg, setting fermentation temperature 37 DEG C, standing for fermentation cultivates 110h, growing white truffle to pH6.0, cryoconcentration, makes every gram containing 0.5 gram of crude drug.Two, microcapsule is coated: weigh the microcapsule wall material modified starch 45 of following weight portion, arabic gum 19, beta-schardinger dextrin-19, syrup 29, joins 400kg and concentrates in bacterium solution, stirring while adding, after mixing and stirring, high pressure homogenize, pressure 18MPa, time 4min, is spray-dried, and sets feeding temperature 60 DEG C, feed rate 18L/min, inlet temperature 190 DEG C, leaving air temp 70 DEG C, cool, obtain laying hen finishing period Chinese medicine feed additive, add in laying hens essential ration by 6%.
Embodiment 24
A kind of preparation method of laying hen finishing period Chinese medicine feed additive, comprise the following steps: one, Chinese medicine extract: weigh the Flos lonicerae 140 of following weight portion, Indigo Naturalis 140, Fructus Ligustri Lucidi 140, Herba Leonuri 140, Rhizoma Coptidis 120, Herba Chenopodii 120, Pericarpium Citri Reticulatae 120, Radix Sophorae Flavescentis 120, Fructus Crataegi (parched to brown) 100, the Radix Astragali 100, Radix Angelicae Sinensis 100, Hyodeoxycholic Acid 80, Radix Glycyrrhizae 60, by the ethanol solution of the 90% of each Study on Supermicro-pulverization of Traditional Chinese Drugs addition Chinese medicine gross weight 8 times amount, soak 60min, intense fire boils, slow fire insulation 30min, cools down Floor 12 filtered through gauze；Filtering residue adds the ethanol solution of the 70% of 6 times amount again, and intense fire boils, slow fire insulation 60min, cooling Floor 12 filtered through gauze, merges twice filtrate, concentration and recovery ethanol, concentrate without stopping during ethanol with in ethanol detector detection concentrated solution, add water in concentrated solution and make every milliliter of water crude drug Han 0.25g.White sugar 20Kg is added in units of 100 Kg concentrated solutions, and boil 5min, it is cooled to room temperature, inoculating lactobacillus, acetobacter xylinum and yeast (commercially available) preparation 25Kg, setting fermentation temperature 38 DEG C, standing for fermentation cultivates 96h, growing white truffle to pH5.5, cryoconcentration, makes every gram containing 0.5 gram of crude drug.Two, microcapsule is coated: weigh the microcapsule wall material modified starch 47 of following weight portion, arabic gum 20, beta-schardinger dextrin-20, syrup 30, joins 440kg and concentrates in bacterium solution, stirring while adding, after mixing and stirring, high pressure homogenize, pressure 16MPa, time 4min, is spray-dried, and sets feeding temperature 60 DEG C, feed rate 20L/min, inlet temperature 190 DEG C, leaving air temp 70 DEG C, cool, obtain laying hen finishing period Chinese medicine feed additive, add in laying hens essential ration by 7%.
Embodiment 25
A kind of preparation method of laying hen finishing period Chinese medicine feed additive, comprise the following steps: one, Chinese medicine extract: weigh the Flos lonicerae 130 of following weight portion, Indigo Naturalis 130, Fructus Ligustri Lucidi 130, Herba Leonuri 130, Rhizoma Coptidis 110, Herba Chenopodii 110, Pericarpium Citri Reticulatae 110, Radix Sophorae Flavescentis 110, Fructus Crataegi (parched to brown) 90, the Radix Astragali 90, Radix Angelicae Sinensis 90, Hyodeoxycholic Acid 70, Radix Glycyrrhizae 50, by the ethanol solution of the 80% of each Study on Supermicro-pulverization of Traditional Chinese Drugs addition Chinese medicine gross weight 7 times amount, soak 60min, intense fire boils, slow fire insulation 60min, cools down Floor 12 filtered through gauze；Filtering residue adds the ethanol solution of the 65% of 4 times amount again, and intense fire boils, slow fire insulation 40min, cooling Floor 12 filtered through gauze, merges twice filtrate, concentration and recovery ethanol, concentrate without stopping during ethanol with in ethanol detector detection concentrated solution, add water in concentrated solution and make every milliliter of water crude drug Han 0.25g.White sugar 11Kg is added in units of 100 Kg concentrated solutions, and boil 3.5min, it is cooled to room temperature, inoculating lactobacillus, acetobacter xylinum and yeast (commercially available) preparation 25Kg, setting fermentation temperature 35 DEG C, standing for fermentation cultivates 120h, growing white truffle to pH5.8, cryoconcentration, makes every gram containing 0.5 gram of crude drug.Two, microcapsule is coated: weigh the microcapsule wall material modified starch 50 of following weight portion, arabic gum 20, beta-schardinger dextrin-20, syrup 30, joins 450kg and concentrates in bacterium solution, stirring while adding, after mixing and stirring, high pressure homogenize, pressure 11MPa, time 3.5min, is spray-dried, and sets feeding temperature 53 DEG C, feed rate 16L/min, inlet temperature 185 DEG C, leaving air temp 63 DEG C, cool, obtain laying hen finishing period Chinese medicine feed additive, add in laying hens essential ration by 8%.
Embodiment 26
A kind of preparation method of laying hen finishing period Chinese medicine feed additive, comprise the following steps: one, Chinese medicine extract: weigh the Flos lonicerae 130 of following weight portion, Indigo Naturalis 130, Fructus Ligustri Lucidi 130, Herba Leonuri 130, Rhizoma Coptidis 110, Herba Chenopodii 110, Pericarpium Citri Reticulatae 110, Radix Sophorae Flavescentis 110, Fructus Crataegi (parched to brown) 90, the Radix Astragali 90, Radix Angelicae Sinensis 90, Hyodeoxycholic Acid 70, Radix Glycyrrhizae 50, by the ethanol solution of the 90% of each Study on Supermicro-pulverization of Traditional Chinese Drugs addition Chinese medicine gross weight 7 times amount, soak 60min, intense fire boils, slow fire insulation 60min, cools down Floor 12 filtered through gauze；Filtering residue adds the ethanol solution of the 70% of 5 times amount again, and intense fire boils, slow fire insulation 60min, cooling Floor 12 filtered through gauze, merges twice filtrate, concentration and recovery ethanol, concentrate without stopping during ethanol with in ethanol detector detection concentrated solution, add water in concentrated solution and make every milliliter of water crude drug Han 0.25g.White sugar 20Kg is added in units of 100 Kg concentrated solutions, and boil 5min, it is cooled to room temperature, inoculating lactobacillus, acetobacter xylinum and yeast (commercially available) preparation 25Kg, setting fermentation temperature 37 DEG C, standing for fermentation cultivates 110h, growing white truffle to pH6.2, cryoconcentration, makes every gram containing 0.5 gram of crude drug.Two, microcapsule is coated: weigh the microcapsule wall material modified starch 49 of following weight portion, arabic gum 19, beta-schardinger dextrin-19, syrup 27, joins 470kg and concentrates in bacterium solution, stirring while adding, after mixing and stirring, high pressure homogenize, pressure 17MPa, time 4.5min, is spray-dried, and sets feeding temperature 53 DEG C, feed rate 17L/min, inlet temperature 187 DEG C, leaving air temp 65 DEG C, cool, obtain laying hen finishing period Chinese medicine feed additive, add in laying hens essential ration by 8%.
Embodiment 27
A kind of preparation method of laying hen finishing period Chinese medicine feed additive, comprise the following steps: one, Chinese medicine extract: weigh the Flos lonicerae 130 of following weight portion, Indigo Naturalis 130, Fructus Ligustri Lucidi 130, Herba Leonuri 130, Rhizoma Coptidis 110, Herba Chenopodii 110, Pericarpium Citri Reticulatae 110, Radix Sophorae Flavescentis 110, Fructus Crataegi (parched to brown) 90, the Radix Astragali 90, Radix Angelicae Sinensis 90, Hyodeoxycholic Acid 70, Radix Glycyrrhizae 50, by the ethanol solution of the 80% of each Study on Supermicro-pulverization of Traditional Chinese Drugs addition Chinese medicine gross weight 7 times amount, soak 30min, intense fire boils, slow fire insulation 60min, cools down Floor 12 filtered through gauze；Filtering residue adds the ethanol solution of the 70% of 6 times amount again, and intense fire boils, slow fire insulation 60min, cooling Floor 12 filtered through gauze, merges twice filtrate, concentration and recovery ethanol, concentrate without stopping during ethanol with in ethanol detector detection concentrated solution, add water in concentrated solution and make every milliliter of water crude drug Han 0.25g.White sugar 17Kg is added in units of 100 Kg concentrated solutions, and boil 5min, it is cooled to room temperature, inoculating lactobacillus, acetobacter xylinum and yeast (commercially available) preparation 24Kg, setting fermentation temperature 38 DEG C, standing for fermentation cultivates 120h, growing white truffle to pH6.5, cryoconcentration, makes every gram containing 0.5 gram of crude drug.Two, microcapsule is coated: weigh the microcapsule wall material modified starch 52 of following weight portion, arabic gum 18, beta-schardinger dextrin-19, syrup 30, joins 500kg and concentrates in bacterium solution, stirring while adding, after mixing and stirring, high pressure homogenize, pressure 20MPa, time 5min, is spray-dried, and sets feeding temperature 60 DEG C, feed rate 20L/min, inlet temperature 190 DEG C, leaving air temp 70 DEG C, cool, obtain laying hen finishing period Chinese medicine feed additive, add in laying hens essential ration by 7%.
Embodiment 28
A kind of preparation method of laying hen finishing period Chinese medicine feed additive, comprise the following steps: one, Chinese medicine extract: weigh the Flos lonicerae 130 of following weight portion, Indigo Naturalis 130, Fructus Ligustri Lucidi 130, Herba Leonuri 130, Rhizoma Coptidis 110, Herba Chenopodii 110, Pericarpium Citri Reticulatae 110, Radix Sophorae Flavescentis 110, Fructus Crataegi (parched to brown) 90, the Radix Astragali 90, Radix Angelicae Sinensis 90, Hyodeoxycholic Acid 70, Radix Glycyrrhizae 50, by the ethanol solution of the 85% of each Study on Supermicro-pulverization of Traditional Chinese Drugs addition Chinese medicine gross weight 7 times amount, soak 60min, intense fire boils, slow fire insulation 60min, cools down Floor 12 filtered through gauze；Filtering residue adds the ethanol solution of the 65% of 5 times amount again, and intense fire boils, slow fire insulation 60min, cooling Floor 12 filtered through gauze, merges twice filtrate, concentration and recovery ethanol, concentrate without stopping during ethanol with in ethanol detector detection concentrated solution, add water in concentrated solution and make every milliliter of water crude drug Han 0.25g.White sugar 16Kg is added in units of 100 Kg concentrated solutions, and boil 4.5min, it is cooled to room temperature, inoculating lactobacillus, acetobacter xylinum and yeast (commercially available) preparation 25Kg, setting fermentation temperature 38 DEG C, standing for fermentation cultivates 114h, growing white truffle to pH6.5, cryoconcentration, makes every gram containing 0.5 gram of crude drug.Two, microcapsule is coated: weigh the microcapsule wall material modified starch 55 of following weight portion, arabic gum 17, beta-schardinger dextrin-18, syrup 28, joins 450kg and concentrates in bacterium solution, stirring while adding, after mixing and stirring, high pressure homogenize, pressure 20MPa, time 5min, is spray-dried, and sets feeding temperature 55 DEG C, feed rate 17L/min, inlet temperature 187 DEG C, leaving air temp 65 DEG C, cool, obtain laying hen finishing period Chinese medicine feed additive, add in laying hens essential ration by 6%.
Embodiment 29
A kind of preparation method of laying hen finishing period Chinese medicine feed additive, comprise the following steps: one, Chinese medicine extract: weigh the Flos lonicerae 130 of following weight portion, Indigo Naturalis 130, Fructus Ligustri Lucidi 130, Herba Leonuri 130, Rhizoma Coptidis 110, Herba Chenopodii 110, Pericarpium Citri Reticulatae 110, Radix Sophorae Flavescentis 110, Fructus Crataegi (parched to brown) 90, the Radix Astragali 90, Radix Angelicae Sinensis 90, Hyodeoxycholic Acid 70, Radix Glycyrrhizae 50, by the ethanol solution of the 85% of each Study on Supermicro-pulverization of Traditional Chinese Drugs addition Chinese medicine gross weight 7 times amount, soak 60min, intense fire boils, slow fire insulation 60min, cools down Floor 12 filtered through gauze；Filtering residue adds the ethanol solution of the 70% of 5 times amount again, and intense fire boils, slow fire insulation 60min, cooling Floor 12 filtered through gauze, merges twice filtrate, concentration and recovery ethanol, concentrate without stopping during ethanol with in ethanol detector detection concentrated solution, add water in concentrated solution and make every milliliter of water crude drug Han 0.25g.White sugar 20Kg is added in units of 100 Kg concentrated solutions, and boil 5min, it is cooled to room temperature, inoculating lactobacillus, acetobacter xylinum and yeast (commercially available) preparation 25Kg, setting fermentation temperature 38 DEG C, standing for fermentation cultivates 96h, growing white truffle to pH5.6, cryoconcentration, makes every gram containing 0.5 gram of crude drug.Two, microcapsule is coated: weigh the microcapsule wall material modified starch 52 of following weight portion, arabic gum 20, beta-schardinger dextrin-20, syrup 30, joins 480kg and concentrates in bacterium solution, stirring while adding, after mixing and stirring, high pressure homogenize, pressure 17MPa, time 4.5min, is spray-dried, and sets feeding temperature 57 DEG C, feed rate 17L/min, inlet temperature 188 DEG C, leaving air temp 63 DEG C, cool, obtain laying hen finishing period Chinese medicine feed additive, add in laying hens essential ration by 6%.
Embodiment 30
A kind of preparation method of laying hen finishing period Chinese medicine feed additive, comprise the following steps: one, Chinese medicine extract: weigh the Flos lonicerae 130 of following weight portion, Indigo Naturalis 130, Fructus Ligustri Lucidi 130, Herba Leonuri 130, Rhizoma Coptidis 110, Herba Chenopodii 110, Pericarpium Citri Reticulatae 110, Radix Sophorae Flavescentis 110, Fructus Crataegi (parched to brown) 90, the Radix Astragali 90, Radix Angelicae Sinensis 90, Hyodeoxycholic Acid 70, Radix Glycyrrhizae 50, by the ethanol solution of the 85% of each Study on Supermicro-pulverization of Traditional Chinese Drugs addition Chinese medicine gross weight 7 times amount, soak 50min, intense fire boils, slow fire insulation 40min, cools down Floor 12 filtered through gauze；Filtering residue adds the ethanol solution of the 65% of 5 times amount again, and intense fire boils, slow fire insulation 50min, cooling Floor 12 filtered through gauze, merges twice filtrate, concentration and recovery ethanol, concentrate without stopping during ethanol with in ethanol detector detection concentrated solution, add water in concentrated solution and make every milliliter of water crude drug Han 0.25g.White sugar 17Kg is added in units of 100 Kg concentrated solutions, and boil 3.5min, it is cooled to room temperature, inoculating lactobacillus, acetobacter xylinum and yeast (commercially available) preparation 23Kg, setting fermentation temperature 38 DEG C, standing for fermentation cultivates 96h, growing white truffle to pH5.5, cryoconcentration, makes every gram containing 0.5 gram of crude drug.Two, microcapsule is coated: weigh the microcapsule wall material modified starch 45 of following weight portion, arabic gum 20, beta-schardinger dextrin-20, syrup 25, join 455kg and concentrate in bacterium solution, stirring while adding, after mixing and stirring, high pressure homogenize, pressure 12.5MPa, time 4.5min, is spray-dried, and sets feeding temperature 53 DEG C, feed rate 16L/min, inlet temperature 187 DEG C, leaving air temp 63 DEG C, cool, obtain laying hen finishing period Chinese medicine feed additive, add in laying hens essential ration by 4%.
Embodiment 31
A kind of preparation method of Egg Production of Laying Hens early stage Chinese medicine feed additive, comprise the following steps: one, Chinese medicine extract: weigh the Flos lonicerae 130 of following weight portion, Indigo Naturalis 130, Fructus Ligustri Lucidi 130, Herba Leonuri 130, Rhizoma Coptidis 110, Herba Chenopodii 110, Pericarpium Citri Reticulatae 110, Radix Sophorae Flavescentis 110, Fructus Crataegi (parched to brown) 90, the Radix Astragali 90, Radix Angelicae Sinensis 90, Hyodeoxycholic Acid 70, Radix Glycyrrhizae 50, by the ethanol solution of the 85% of each Study on Supermicro-pulverization of Traditional Chinese Drugs addition Chinese medicine gross weight 7 times amount, soak 60min, intense fire boils, slow fire insulation 60min, cools down Floor 12 filtered through gauze；Filtering residue adds the ethanol solution of the 65% of 5 times amount again, intense fire boils, slow fire insulation 35min, cooling Floor 12 filtered through gauze, merge twice filtrate, concentration and recovery ethanol, concentrate without stopping during ethanol with in ethanol detector detection concentrated solution, add water in concentrated solution and make every milliliter of water crude drug Han 0.25g, white sugar 18Kg is added in units of 100 Kg concentrated solutions, and boil 4.5min, it is cooled to room temperature, inoculating lactobacillus, acetobacter xylinum and yeast (commercially available) preparation 22.5Kg, set fermentation temperature 38 DEG C, standing for fermentation cultivates 96h, growing white truffle to pH5.5, cryoconcentration, make every gram containing 0.5 gram of crude drug.Two, microcapsule is coated: weigh the microcapsule wall material modified starch 48 of following weight portion, arabic gum 18, beta-schardinger dextrin-20, syrup 30, joins in the bacterium solution that 460kg concentrates, stirring while adding, after mixing and stirring, the pressure 15MPa of high pressure homogenize, time 3.5min, feeding temperature 53 DEG C of spraying, feed rate 18L/min, inlet temperature 188 DEG C, leaving air temp 65 DEG C, cool, obtain Egg Production of Laying Hens early stage Chinese medicine feed additive, add in laying hens essential ration by 5%.
Embodiment 32
A kind of preparation method of Egg Production of Laying Hens early stage Chinese medicine feed additive, comprise the following steps: one, Chinese medicine extract: weigh the Flos lonicerae 130 of following weight portion, Indigo Naturalis 130, Fructus Ligustri Lucidi 130, Herba Leonuri 130, Rhizoma Coptidis 110, Herba Chenopodii 110, Pericarpium Citri Reticulatae 110, Radix Sophorae Flavescentis 110, Fructus Crataegi (parched to brown) 90, the Radix Astragali 90, Radix Angelicae Sinensis 90, Hyodeoxycholic Acid 70, Radix Glycyrrhizae 50, by the ethanol solution of the 90% of each Study on Supermicro-pulverization of Traditional Chinese Drugs addition Chinese medicine gross weight 6 times amount, soak 35min, intense fire boils, slow fire insulation 55min, cools down Floor 12 filtered through gauze；Filtering residue adds the ethanol solution of the 70% of 6 times amount again, intense fire boils, slow fire insulation 60min, cooling Floor 12 filtered through gauze, merge twice filtrate, concentration and recovery ethanol, concentrate without stopping during ethanol with in ethanol detector detection concentrated solution, add water in concentrated solution and make every milliliter of water crude drug Han 0.25g, white sugar 16Kg is added in units of 100 Kg concentrated solutions, and boil 4.5min, it is cooled to room temperature, inoculating lactobacillus, acetobacter xylinum and yeast (commercially available) preparation 22.5Kg, set fermentation temperature 37 DEG C, standing for fermentation cultivates 108h, growing white truffle to pH6.5, cryoconcentration, make every gram containing 0.5 gram of crude drug.Two, microcapsule is coated: weigh the microcapsule wall material modified starch 55 of following weight portion, arabic gum 15, beta-schardinger dextrin-15, syrup 25, joins in the bacterium solution that 460kg concentrates, stirring while adding, after mixing and stirring, the pressure 17MPa of high pressure homogenize, time 3.5min, feeding temperature 51 DEG C of spraying, feed rate 16L/min, inlet temperature 190 DEG C, leaving air temp 60 DEG C, cool, obtain Egg Production of Laying Hens early stage Chinese medicine feed additive, add in laying hens essential ration by 7%.
Embodiment 33
A kind of preparation method of Egg Production of Laying Hens early stage Chinese medicine feed additive, comprise the following steps: one, Chinese medicine extract: weigh the Flos lonicerae 130 of following weight portion, Indigo Naturalis 130, Fructus Ligustri Lucidi 130, Herba Leonuri 130, Rhizoma Coptidis 110, Herba Chenopodii 110, Pericarpium Citri Reticulatae 110, Radix Sophorae Flavescentis 110, Fructus Crataegi (parched to brown) 90, the Radix Astragali 90, Radix Angelicae Sinensis 90, Hyodeoxycholic Acid 70, Radix Glycyrrhizae 50, by the ethanol solution of the 85% of each Study on Supermicro-pulverization of Traditional Chinese Drugs addition Chinese medicine gross weight 7 times amount, soak 30min, intense fire boils, slow fire insulation 60min, cools down Floor 12 filtered through gauze；Filtering residue adds the ethanol solution of the 70% of 6 times amount again, intense fire boils, slow fire insulation 45min, cooling Floor 12 filtered through gauze, merge twice filtrate, concentration and recovery ethanol, concentrate without stopping during ethanol with in ethanol detector detection concentrated solution, add water in concentrated solution and make every milliliter of water crude drug Han 0.25g, white sugar 20Kg is added in units of 100 Kg concentrated solutions, and boil 5min, it is cooled to room temperature, inoculating lactobacillus, acetobacter xylinum and yeast (commercially available) preparation 25Kg, set fermentation temperature 35 DEG C, standing for fermentation cultivates 114h, growing white truffle to pH6.5, cryoconcentration, make every gram containing 0.5 gram of crude drug.Two, microcapsule is coated: weigh the microcapsule wall material modified starch 49 of following weight portion, arabic gum 19, beta-schardinger dextrin-20, syrup 30, joins in the bacterium solution that 500kg concentrates, stirring while adding, after mixing and stirring, the pressure 20MPa of high pressure homogenize, time 3.5min, feeding temperature 57 DEG C of spraying, feed rate 18L/min, inlet temperature 189 DEG C, leaving air temp 65 DEG C, cool, obtain Egg Production of Laying Hens early stage Chinese medicine feed additive, add in laying hens essential ration by 8%.
Embodiment 34
A kind of preparation method of Egg Production of Laying Hens early stage Chinese medicine feed additive, comprise the following steps: one, Chinese medicine extract: weigh the Flos lonicerae 130 of following weight portion, Indigo Naturalis 130, Fructus Ligustri Lucidi 130, Herba Leonuri 130, Rhizoma Coptidis 110, Herba Chenopodii 110, Pericarpium Citri Reticulatae 110, Radix Sophorae Flavescentis 110, Fructus Crataegi (parched to brown) 90, the Radix Astragali 90, Radix Angelicae Sinensis 90, Hyodeoxycholic Acid 70, Radix Glycyrrhizae 50, by the ethanol solution of the 90% of each Study on Supermicro-pulverization of Traditional Chinese Drugs addition Chinese medicine gross weight 8 times amount, soak 60min, intense fire boils, slow fire insulation 60min, cools down Floor 12 filtered through gauze；Filtering residue adds the ethanol solution of the 70% of 4 times amount again, intense fire boils, slow fire insulation 30～60min, cooling Floor 12 filtered through gauze, merge twice filtrate, concentration and recovery ethanol, concentrate without stopping during ethanol with in ethanol detector detection concentrated solution, add water in concentrated solution and make every milliliter of water crude drug Han 0.25g, white sugar 20Kg is added in units of 100 Kg concentrated solutions, and boil 4.5min, it is cooled to room temperature, inoculating lactobacillus, acetobacter xylinum and yeast (commercially available) preparation 25Kg, set fermentation temperature 38 DEG C, standing for fermentation cultivates 96h, growing white truffle to pH6.5, cryoconcentration, make every gram containing 0.5 gram of crude drug.Two, microcapsule is coated: weigh the microcapsule wall material modified starch 49 of following weight portion, arabic gum 17, beta-schardinger dextrin-16, syrup 28, joins in the bacterium solution that 500kg concentrates, stirring while adding, after mixing and stirring, the pressure 20MPa of high pressure homogenize, time 5min, feeding temperature 60 DEG C of spraying, feed rate 20L/min, inlet temperature 190 DEG C, leaving air temp 70 DEG C, cool, obtain Egg Production of Laying Hens early stage Chinese medicine feed additive, add in laying hens essential ration by 7%.
Embodiment 35
A kind of preparation method of Egg Production of Laying Hens early stage Chinese medicine feed additive, comprise the following steps: one, Chinese medicine extract: weigh the Flos lonicerae 130 of following weight portion, Indigo Naturalis 130, Fructus Ligustri Lucidi 130, Herba Leonuri 130, Rhizoma Coptidis 110, Herba Chenopodii 110, Pericarpium Citri Reticulatae 110, Radix Sophorae Flavescentis 110, Fructus Crataegi (parched to brown) 90, the Radix Astragali 90, Radix Angelicae Sinensis 90, Hyodeoxycholic Acid 70, Radix Glycyrrhizae 50, by the ethanol solution of the 85% of each Study on Supermicro-pulverization of Traditional Chinese Drugs addition Chinese medicine gross weight 7 times amount, soak 60min, intense fire boils, slow fire insulation 30min, cools down Floor 12 filtered through gauze；Filtering residue adds the ethanol solution of the 65% of 5 times amount again, intense fire boils, slow fire insulation 45min, cooling Floor 12 filtered through gauze, merge twice filtrate, concentration and recovery ethanol, concentrate without stopping during ethanol with in ethanol detector detection concentrated solution, add water in concentrated solution and make every milliliter of water crude drug Han 0.25g, white sugar 17Kg is added in units of 100 Kg concentrated solutions, and boil 3.5min, it is cooled to room temperature, inoculating lactobacillus, acetobacter xylinum and yeast (commercially available) preparation 25Kg, set fermentation temperature 38 DEG C, standing for fermentation cultivates 96h, growing white truffle to pH5.5, cryoconcentration, make every gram containing 0.5 gram of crude drug.Two, microcapsule is coated: weigh the microcapsule wall material modified starch 55 of following weight portion, arabic gum 20, beta-schardinger dextrin-20, syrup 30, joins in the bacterium solution that 500kg concentrates, stirring while adding, after mixing and stirring, the pressure 19MPa of high pressure homogenize, time 4.5min, feeding temperature 60 DEG C of spraying, feed rate 20L/min, inlet temperature 190 DEG C, leaving air temp 70 DEG C, cool, obtain Egg Production of Laying Hens early stage Chinese medicine feed additive, add in laying hens essential ration by 6%.
Embodiment 36
A kind of preparation method of Egg Production of Laying Hens early stage Chinese medicine feed additive, comprise the following steps: one, Chinese medicine extract: weigh the Flos lonicerae 130 of following weight portion, Indigo Naturalis 130, Fructus Ligustri Lucidi 130, Herba Leonuri 130, Rhizoma Coptidis 110, Herba Chenopodii 110, Pericarpium Citri Reticulatae 110, Radix Sophorae Flavescentis 110, Fructus Crataegi (parched to brown) 90, the Radix Astragali 90, Radix Angelicae Sinensis 90, Hyodeoxycholic Acid 70, Radix Glycyrrhizae 50, by the ethanol solution of the 90% of each Study on Supermicro-pulverization of Traditional Chinese Drugs addition Chinese medicine gross weight 8 times amount, soak 30min, intense fire boils, slow fire insulation 60min, cools down Floor 12 filtered through gauze；Filtering residue adds the ethanol solution of the 65% of 5 times amount again, intense fire boils, slow fire insulation 45min, cooling Floor 12 filtered through gauze, merge twice filtrate, concentration and recovery ethanol, concentrate without stopping during ethanol with in ethanol detector detection concentrated solution, add water in concentrated solution and make every milliliter of water crude drug Han 0.25g, white sugar 20Kg is added in units of 100 Kg concentrated solutions, and boil 5min, it is cooled to room temperature, inoculating lactobacillus, acetobacter xylinum and yeast (commercially available) preparation 22.5Kg, set fermentation temperature 38 DEG C, standing for fermentation cultivates 96h, growing white truffle to pH5.5, cryoconcentration, make every gram containing 0.5 gram of crude drug.Two, microcapsule is coated: weigh the microcapsule wall material modified starch 55 of following weight portion, arabic gum 20, beta-schardinger dextrin-20, syrup 30, joins in the bacterium solution that 450kg concentrates, stirring while adding, after mixing and stirring, the pressure 17MPa of high pressure homogenize, time 3.5min, feeding temperature 55 DEG C of spraying, feed rate 16L/min, inlet temperature 187 DEG C, leaving air temp 65 DEG C, cool, obtain Egg Production of Laying Hens early stage Chinese medicine feed additive, add in laying hens essential ration by 8%.
The above; being only the detailed description of the invention of the present invention, but protection scope of the present invention is not limited thereto, any those familiar with the art is in the technical scope that the invention discloses; change can be readily occurred in or replace, all should contain within protection scope of the present invention.

Claims (6)

  1. null1. the preparation method of a laying hen finishing period Chinese medicine feed additive，It is characterized in that: it is to prepare according to the following steps: one、Chinese medicine extract: Flos lonicerae 120-140、Indigo Naturalis 120-140、Fructus Ligustri Lucidi 120-140、Herba Leonuri 120-140、Rhizoma Coptidis 100-120、Herba Chenopodii 100-120、Pericarpium Citri Reticulatae 100-120、Radix Sophorae Flavescentis 100-120、Fructus Crataegi (parched to brown) 80-100、Radix Astragali 80-100、Radix Angelicae Sinensis 80-100、Hyodeoxycholic Acid 60-80、Radix Glycyrrhizae 40-60，Each Study on Supermicro-pulverization of Traditional Chinese Drugs is added ethanol solution intense fire boil，Slow fire is incubated，Cold filtration，Concentrated filtrate，Add white sugar to boil，Cool down to inoculating lactobacillus after room temperature、Acetobacter xylinum and yeast，Through 96 ~ 120h fermentation to growing white truffle，By bacterium solution cryoconcentration；Two, microcapsule is coated: weigh the microcapsule wall material modified starch 45-55 of following weight portion, arabic gum 15-20, beta-schardinger dextrin-15-20, syrup 25-30, join in the bacterium solution that 400-500kg concentrates, stirring while adding, after mixing and stirring, high pressure homogenize, it is spray-dried, obtains laying hen finishing period Chinese medicine feed additive, add in laying hens essential ration by 4%-8%.
  2. The preparation method of a kind of laying hen finishing period Chinese medicine feed additive the most according to claim 1, it is characterized in that: weigh the Chinese medicine of weight portion in proportion, by its micronizing, the ethanol solution of 80%～the 90% of addition Chinese medicine gross weight 6～8 times amount, soak 30～60min, intense fire boils, slow fire insulation 30～60min, cools down Floor 12 filtered through gauze；Filtering residue adds 4～the ethanol solution of the 60% of 6 times amount～70% again, intense fire boils, slow fire insulation 30～60min, cooling Floor 12 filtered through gauze, merge twice filtrate, concentration and recovery ethanol, concentrates without stopping during ethanol with in ethanol detector detection concentrated solution, adds water and make every milliliter of water crude drug Han 0.25g in concentrated solution.
  3. The preparation method of a kind of laying hen finishing period Chinese medicine feed additive the most according to claim 1, it is characterized in that: in units of 100 Kg concentrated solutions, add white sugar 10～20Kg, and boil 3～5min, it is cooled to room temperature, inoculating lactobacillus, acetobacter xylinum and yeast (commercially available) preparation 20～25Kg, setting fermentation temperature 35～38 DEG C, standing for fermentation cultivates 96～120h, growing white truffle to pH5.5 ~ 6.5, cryoconcentration, make every gram containing 0.5 gram of crude drug.
  4. The preparation method of a kind of laying hen finishing period Chinese medicine feed additive the most according to claim 1, it is characterised in that: the pressure 10-20MPa of high pressure homogenize, Time 3-5min.
  5. The preparation method of a kind of laying hen finishing period Chinese medicine feed additive the most according to claim 1, it is characterised in that: spraying feeding temperature 50-60 DEG C, feed rate 15-20L/min, inlet temperature 185-190 DEG C, leaving air temp 60-70 DEG C.
  6. The preparation method of a kind of laying hen finishing period Chinese medicine feed additive the most according to claim 1, it is characterised in that: step one is carried out in aseptic fermenting cellar.
CN201610521543.7A 2016-07-05 2016-07-05 Preparing method for traditional Chinese medicine feed additive in laying hen growing period Pending CN105995179A (en)

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CN106819536A (en) * 2016-12-27 2017-06-13 广东杨氏农业有限公司 Green nourishing feed for producing just raw egg laying hen
CN107149050A (en) * 2017-06-21 2017-09-12 沭阳益客食品有限公司 Chinese herbal feed additive for laying hen health care and preparation method thereof
CN107183398A (en) * 2017-04-28 2017-09-22 陕西师范大学 A kind of feed for improving chicken egg productivity and preparation method thereof
CN107198055A (en) * 2017-07-06 2017-09-26 胡友军 Improve the premix of Layer Production Performance with improving Egg Quality and its preparation method and application

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CN106819536A (en) * 2016-12-27 2017-06-13 广东杨氏农业有限公司 Green nourishing feed for producing just raw egg laying hen
CN107183398A (en) * 2017-04-28 2017-09-22 陕西师范大学 A kind of feed for improving chicken egg productivity and preparation method thereof
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