CN102526223A - Chinese medicinal composition having liver-protecting and gallbladder-benefiting functions and preparation method thereof - Google Patents
Chinese medicinal composition having liver-protecting and gallbladder-benefiting functions and preparation method thereof Download PDFInfo
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- CN102526223A CN102526223A CN2010105815000A CN201010581500A CN102526223A CN 102526223 A CN102526223 A CN 102526223A CN 2010105815000 A CN2010105815000 A CN 2010105815000A CN 201010581500 A CN201010581500 A CN 201010581500A CN 102526223 A CN102526223 A CN 102526223A
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Abstract
The invention relates to a Chinese medicinal composition having liver-protecting and gallbladder-benefiting functions. The Chinese medicinal composition consists of the following components in parts by weight: 20-40 parts of isatis root, 10-30 parts of rhubarb, 10-30 parts of baikal skullcap root, 10-30 parts of astragalus, 20-40 parts of honeysuckle flower and 5-10 parts of allicin. The Chinese medicinal composition has the advantages of liver-protecting and gallbladder-benefiting effects, scientific and reasonable formula composition, no toxic or side effect, no medicament residue, convenience for using, safety and reliability, and is a low-cost Chinese medicinal composition having liver-protecting and gallbladder-benefiting functions.
Description
Technical field
The invention belongs to field of veterinary, especially a kind of Chinese medicine composition and preparation method thereof with hepatic cholagogic function.
Background technology
Along with the fast development of China's freshwater aquaculture industry, cultured area and production-scale continuous expansion, intensification the improving constantly of degree, the rapid increase of cultured output, people also more and more pay attention to treatment the control of aquatic animal disease.
In recent years, the generation of fish diseases is serious day by day, and having occurred with liver and gall is the fish disease of principal character, i.e. liver and gall syndrome of fish.When the state of an illness was light, the fish body did not generally have tangible symptom, and fish body colour, the bodily form etc. do not have obviously and change, inappetence only, and it is unable to move about, restless sometimes, even the water surface of scurrying out, poor growth, mortality rate is not high; When being in a bad way, fish body colour blackout, color and luster is dark and gloomy, and the fish body has the edema sense, and scale is loosening to be prone to come off, and it is irregular to move about, disequilibrium, or be still in the water, appetite descends, and reacts dull, and dyspnea, even stupor upset are just dead soon.This disease is the higher a kind of breed disease of sickness rate in recent years, and hazardness is bigger, and adult fish of Ctenopharyngodon idellus, Mylopharyngodon piceus, Carassius auratus and fingerling all possibly take place; And treat than refractory; Yin Qichang is with symptoms such as gill rot, red skin, enteritis again, and mistaken diagnosis has easily caused the certain economic loss directly or indirectly.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicine composition with hepatic cholagogic function, this Chinese medicine composition has the hepatic cholagogic effect, and prescription is formed scientific and reasonable, has no side effect and drug residue, and easy to use, cost is lower.
Another object of the present invention is to provide a kind of method for preparing with Chinese medicine composition of hepatic cholagogic function.
The present invention realizes through following technical scheme:
A kind of Chinese medicine composition with hepatic cholagogic function, its Chinese medicinal composition and ratio of weight and number thereof are:
Radix Isatidis 20-40 part;
Radix Et Rhizoma Rhei 10-30 part;
Radix Scutellariae 10-30 part;
Radix Astragali 10-30 part;
Flos Lonicerae 20-40 part;
Garlicin 5-10 part.
A kind of method for preparing with Chinese medicine composition of hepatic cholagogic function, the step of its preparation method is:
(1). take by weighing Radix Scutellariae, Radix Isatidis, Radix Et Rhizoma Rhei according to proportioning and make solvent with 60-80% ethanol, flood and carry out percolation after 20-30 hour, it is 1.25 clear paste A that percolate reclaims ethanol to relative density, and temperature is controlled at 70～80 ℃;
(2). take by weighing Flos Lonicerae according to proportioning and make solvent with ethanol, flood and carry out percolation after 10-20 hour, percolate recovery ethanol to relative density is 1.31 clear paste B, and temperature is controlled at 70～80 ℃;
(3). take by weighing Radix Astragali decocte with water secondary according to proportioning, each 1-2 hour, collecting decoction; Filter; To be concentrated into relative density be 1.31 to filtrating, and temperature is controlled at 70～80 ℃, with clear paste A, clear paste B, garlicin is full and uniform mixes; Drying can obtain the Chinese medicine composition that finished product has the hepatic cholagogic function.
Advantage of the present invention and beneficial effect are:
1. the Radix Isatidis, Radix Et Rhizoma Rhei, Radix Scutellariae, the Flos Lonicerae that originally have the Chinese medicine composition of hepatic cholagogic function have heat-clearing and toxic substances removing, the curative effect of removing mass clots absorbing; The Radix Astragali has the effect of QI invigorating invigorating middle warmer, can strengthen the resistance against diseases of aquatic animal; Garlicin has the parasiticidal effect of detoxifcation, also plays the food calling effect simultaneously.
2. the method for preparing of Chinese medicine composition that originally has the hepatic cholagogic function is simple, and cost is lower, and its effective ingredient is absorbed by aquatic animal easily, short, instant effect of time.
3. the present invention has the hepatic cholagogic effect, and prescription is formed scientific and reasonable, has no side effect and drug residue, and is easy to use, safe and reliable, is a kind of lower-cost Chinese medicine composition with hepatic cholagogic function.
The specific embodiment
The present invention further details through following examples.Need to prove: following embodiment is illustrative, is not determinate, can not limit protection scope of the present invention with following embodiment.
Radix Isatidis in the component of the present invention, Radix Et Rhizoma Rhei, Radix Scutellariae, the Radix Astragali, Flos Lonicerae, garlicin all can be bought on market and obtain.
Embodiment 1
A kind of Chinese medicine composition with hepatic cholagogic function, its Chinese medicinal composition and weight thereof are respectively: Radix Isatidis 20g, Radix Et Rhizoma Rhei 10g, Radix Scutellariae 10g, Radix Astragali 10g, Flos Lonicerae 40g, garlicin 10g.
A kind of method for preparing with Chinese medicine composition of hepatic cholagogic function, the step of its preparation method is:
(1). take by weighing Radix Scutellariae, Radix Isatidis, Radix Et Rhizoma Rhei according to proportioning and make solvent with 60-80% ethanol, flood and carry out percolation after 20-30 hour, it is 1.25 clear paste A that percolate reclaims ethanol to relative density, and temperature is controlled at 70～80 ℃;
(2). take by weighing Flos Lonicerae according to proportioning and make solvent with ethanol, flood and carry out percolation after 10-20 hour, percolate recovery ethanol to relative density is 1.31 clear paste B, and temperature is controlled at 70～80 ℃;
(3). take by weighing Radix Astragali decocte with water secondary according to proportioning, each 1-2 hour, collecting decoction; Filter; To be concentrated into relative density be 1.31 to filtrating, and temperature is controlled at 70～80 ℃, with clear paste A, clear paste B, garlicin is full and uniform mixes; Drying can obtain the Chinese medicine composition that finished product has the hepatic cholagogic function.
Embodiment 2
A kind of Chinese medicine composition with hepatic cholagogic function, its Chinese medicinal composition and weight thereof are respectively: Radix Isatidis 20g, Radix Et Rhizoma Rhei 30g, Radix Scutellariae 10g, Radix Astragali 10g, Flos Lonicerae 20g, garlicin 10g.
The step of its preparation method is with embodiment 1.
Embodiment 3
A kind of Chinese medicine composition with hepatic cholagogic function, its Chinese medicinal composition and weight thereof are respectively: Radix Isatidis 20g, Radix Et Rhizoma Rhei 10g, Radix Scutellariae 10g, Radix Astragali 30g, Flos Lonicerae 25g, garlicin 5g.
The step of its preparation method is with embodiment 1.
Embodiment 4
A kind of Chinese medicine composition with hepatic cholagogic function, its Chinese medicinal composition and weight thereof are respectively: Radix Isatidis 40g, Radix Et Rhizoma Rhei 10g, Radix Scutellariae 10g, Radix Astragali 10g, Flos Lonicerae 20g, garlicin 10g.
The step of its preparation method is with embodiment 1.
Embodiment 5
A kind of Chinese medicine composition with hepatic cholagogic function, its Chinese medicinal composition and weight thereof are respectively: Radix Isatidis 20g, Radix Et Rhizoma Rhei 10g, Radix Scutellariae 30g, Radix Astragali 10g, Flos Lonicerae 25g, garlicin 5g.
The step of its preparation method is with embodiment 1.
When the present invention used, adding Chinese medicine composition of the present invention in every 100kg aquatic animal feed was 5kg.Described aquatic animal feedstuff can be for buying fish meal, shrimp feedstuff and the Eriocheir sinensis feedstuff that obtains on the market, present embodiment is a fish meal.
Clinical trial
Select 6 net cages, each net cage 200 tail Ctenopharyngodon idellus is divided into two groups at random; Promptly 3 net cages are daily raising group, and three net cages are experimental group, and daily raising group is carried out daily raising; Experimental group adds the present invention in feedstuff; Test period is two months, has carried out clinical pharmacodynamics test of the present invention, result of the test such as following table:
Result of the test shows that experimental group mortality rate sickness rate all is starkly lower than daily raising group, and total survival rate reaches 91%.With SPSS11.0 statistics software analysis, motility rate significant difference (p＜0.05) is formed in experimental group and daily raising.
Claims (2)
1. Chinese medicine composition with hepatic cholagogic function, it is characterized in that: this Chinese medicinal composition and ratio of weight and number thereof are:
Radix Isatidis 20-40 part;
Radix Et Rhizoma Rhei 10-30 part;
Radix Scutellariae 10-30 part;
Radix Astragali 10-30 part;
Flos Lonicerae 20-40 part;
Garlicin 5-10 part.
2. method for preparing with Chinese medicine composition of hepatic cholagogic function, it is characterized in that: the step of this method for preparing is:
(1). take by weighing Radix Scutellariae, Radix Isatidis, Radix Et Rhizoma Rhei according to proportioning and make solvent with 60-80% ethanol, flood and carry out percolation after 20-30 hour, it is 1.25 clear paste A that percolate reclaims ethanol to relative density, and temperature is controlled at 70～80 ℃;
(2). take by weighing Flos Lonicerae according to proportioning and make solvent with ethanol, flood and carry out percolation after 10-20 hour, percolate recovery ethanol to relative density is 1.31 clear paste B, and temperature is controlled at 70～80 ℃;
(3). take by weighing Radix Astragali decocte with water secondary according to proportioning, each 1-2 hour, collecting decoction; Filter; To be concentrated into relative density be 1.31 to filtrating, and temperature is controlled at 70～80 ℃, with clear paste A, clear paste B, garlicin is full and uniform mixes; Drying can obtain the Chinese medicine composition that finished product has the hepatic cholagogic function.
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| CN2010105815000A CN102526223A (en) | 2010-12-09 | 2010-12-09 | Chinese medicinal composition having liver-protecting and gallbladder-benefiting functions and preparation method thereof |
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| CN2010105815000A CN102526223A (en) | 2010-12-09 | 2010-12-09 | Chinese medicinal composition having liver-protecting and gallbladder-benefiting functions and preparation method thereof |
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Cited By (9)
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|---|---|---|---|---|
| CN103610805A (en) * | 2013-11-13 | 2014-03-05 | 赵林斌 | Traditional Chinese medicinal composition for preventing and treating hepatobiliary syndrome of fish |
| CN104366037A (en) * | 2014-01-17 | 2015-02-25 | 海一（厦门）生物科技有限公司 | Aquatic product liver and gallbladder syndrome control feed additive and preparation method thereof |
| CN104886353A (en) * | 2015-07-06 | 2015-09-09 | 诸葛渭航 | Anglerfish feed for preventing liver and gallbladder syndrome and preparation method of anglerfish feed |
| CN105053702A (en) * | 2015-08-28 | 2015-11-18 | 新昌县大成生物科技有限公司 | Health-care feed for anglerfish |
| CN105055965A (en) * | 2015-08-28 | 2015-11-18 | 新昌县大成生物科技有限公司 | Chinese herb composition for treating anglerfish liver and gall syndrome |
| CN105168454A (en) * | 2015-08-28 | 2015-12-23 | 新昌县大成生物科技有限公司 | Traditional Chinese medicine composition for treating anglerfish liver and gall syndromes |
| CN105166479A (en) * | 2015-08-28 | 2015-12-23 | 新昌县大成生物科技有限公司 | Health care feed for anglerfishes |
| CN105166478A (en) * | 2015-08-28 | 2015-12-23 | 新昌县大成生物科技有限公司 | Feed for preventing liver-gallbladder syndrome of anglerfishes |
| CN107469013A (en) * | 2017-09-21 | 2017-12-15 | 胡边文 | A kind of medicament and preparation method for being used to prevent and treat aquatic livestock disease in the liver and gallbladder |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104366037A (en) * | 2014-01-17 | 2015-02-25 | 海一（厦门）生物科技有限公司 | Aquatic product liver and gallbladder syndrome control feed additive and preparation method thereof |
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| CN105053702A (en) * | 2015-08-28 | 2015-11-18 | 新昌县大成生物科技有限公司 | Health-care feed for anglerfish |
| CN105055965A (en) * | 2015-08-28 | 2015-11-18 | 新昌县大成生物科技有限公司 | Chinese herb composition for treating anglerfish liver and gall syndrome |
| CN105168454A (en) * | 2015-08-28 | 2015-12-23 | 新昌县大成生物科技有限公司 | Traditional Chinese medicine composition for treating anglerfish liver and gall syndromes |
| CN105166479A (en) * | 2015-08-28 | 2015-12-23 | 新昌县大成生物科技有限公司 | Health care feed for anglerfishes |
| CN105166478A (en) * | 2015-08-28 | 2015-12-23 | 新昌县大成生物科技有限公司 | Feed for preventing liver-gallbladder syndrome of anglerfishes |
| CN107469013A (en) * | 2017-09-21 | 2017-12-15 | 胡边文 | A kind of medicament and preparation method for being used to prevent and treat aquatic livestock disease in the liver and gallbladder |
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Application publication date: 20120704 |