Summary of the invention
Object of the present invention is just to provide the Chinese herbal compound preparation of the concurrent syndrome of control Ctenopharyngodon idellus entomogenous fungi that a kind of using method is easy, drug effect is fast, safety is high.
The Chinese herbal compound preparation of the concurrent syndrome of control Ctenopharyngodon idellus entomogenous fungi of the present invention, is made up of the raw material of following weight portion: Herba polygoni hydropiperis 35-60 part, Nicotiana tabacum L. 5-60 part, Radix Et Rhizoma Rhei 5-15 part, Radix Artemisia ordosicae 0-20 part.
I type: Ctenopharyngodon idellus entomogenous fungi concurrent syndrome treatment medicine for external use, by its weight parts Herba polygoni hydropiperis, Nicotiana tabacum L., Radix Et Rhizoma Rhei.
II type: Ctenopharyngodon idellus entomogenous fungi concurrent syndrome treatment oral administration medicament, by its weight parts Herba polygoni hydropiperis, Nicotiana tabacum L., Radix Et Rhizoma Rhei, Radix Artemisia ordosicae.
The Chinese herbal compound preparation of the concurrent syndrome of above-mentioned control Ctenopharyngodon idellus entomogenous fungi, its preparation methods steps is as follows: 1, get Herba polygoni hydropiperis, Nicotiana tabacum L., Radix Et Rhizoma Rhei, Radix Artemisia ordosicae, dries rear for subsequent use; 2, Herba polygoni hydropiperis, Nicotiana tabacum L., Radix Et Rhizoma Rhei and Radix Artemisia ordosicae are carried out micronizing respectively; 3, by Herba polygoni hydropiperis, Nicotiana tabacum L., Radix Et Rhizoma Rhei and Radix Artemisia ordosicae powder mix homogeneously, sealing pack.
The Chinese herbal compound preparation of the concurrent syndrome of control Ctenopharyngodon idellus entomogenous fungi of the present invention, using method is as follows:
1, the I type medicine above-mentioned preparation method made, add 10-15 times of water gaging heated and boiled 10 minutes or soak 1 hour with the boiled water (temperature more than 90 DEG C) of 10-15 times amount, evenly splash in the full pond that adds water after cooling, consumption is 2 g/m
3.
2, the II type medicine above-mentioned preparation method made, soak 1 hour with the boiled water (temperature more than 90 DEG C) of 3-5 times amount, add Testa oryzae (or Testa Tritici, rapeseed cake etc.) after cooling to stir, make bait feeding, consumption is that II type medicine 50-100g mixed by every 1 kg bait.
Points for attention: before 1, treating the concurrent syndrome of Ctenopharyngodon idellus entomogenous fungi, Ctenopharyngodon idellus is stopped eating 1 day; 2, treating medication is first that I type, II type medicine sprinkle outward, conbined usage for oral administration, and rising next day can alone II type medicine, within 5-7 days, is a course for the treatment of.3, prevention can alone II type medicine, and pharmaceutical chemistry 1-2 time of monthly throwing something and feeding, is used in conjunction 3-5 days at every turn; 4, I type medicine full pool spilling head is after 24 hours, the new water or change water of should annotating in time.
The Chinese herbal compound preparation of the concurrent syndrome of control Ctenopharyngodon idellus entomogenous fungi of the present invention, by I type, II type Drug combination or be used alone, treatment or the concurrent syndrome of prevention Ctenopharyngodon idellus entomogenous fungi have remarkable result, can reduce disease fish mortality rate and cultivation risk.In addition, this medicine meets NY/T 755 " pollution-free food fisheries drug usage criteria " and NY 5071 " pollution-free food drugs used in aquiculture usage criteria ", can be used for the cultivation of nuisanceless aquatic products and green aquatic product, no drug residue risk.Medicine is cheap and easy to get, and using method is easy, and drug effect is fast, and safety is high, is easy to be accepted by basic unit fisherman, and spread significantly can reduce the economic loss because this disease causes, and its preparation method is simple, is applicable to the needs that large-scale industrial is produced.
The test report of Chinese herbal compound preparation of the present invention:
(1) crude drug basic research
In above-mentioned compound preparation, the result of study such as chemical composition, flavour of a drug performance, medicinal part, the test of pesticide effectiveness of Herba polygoni hydropiperis, Nicotiana tabacum L., Radix Et Rhizoma Rhei, Radix Artemisia ordosicae single medical material sees the following form,
(2) Chinese herbal compound preparation safety testing
get Chinese herbal compound preparation I type of the present invention, II type medicine carries out acute toxicity test, if test group and blank group (3 repeat), often organize 20 tail Ctenopharyngodon idellus.I type drug test was through 96 hours observed and recordeds, and trying to achieve I type safety of medicine concentration is 69, was 34.5 times for the treatment of concentration; II type drug test 5 test group (treatment consumption 1-5 doubly), does not all observe dead fish and toxic reaction phenomenon through cultivation in 10 days; Result of the test shows Chinese herbal compound preparation I type of the present invention, II type Drug safety is very high.
(3) pond treatment and prophylactic tria
1998 so far, and inventor, according to the Ministry of Agriculture " fisheries drug clinical trial technical specification ", applies this Chinese herbal compound preparation and carried out the concurrent syndrome test of 232 pond treatment Ctenopharyngodon idellus entomogenous fungis, the concurrent syndrome test of 28 pond prevention Ctenopharyngodon idellus entomogenous fungis.Administrated method is described above, and efficacy assessment standard is that administration stops dead for 10 days afterwards or only has minority death for effective, and administration stops death toll being obviously reduced to effectively for 10 days afterwards, and it is invalid that administration stops death toll not reducing even aggravation for 10 days afterwards.Test pond quantity and curative effect statistical result in table 1, by following formulae discovery effective percentage (%):
Table 1 Chinese herbal compound preparation pond of the present invention treatment and prophylactic tria result
*
Method |
Pool mouth sum |
Effective pool mouth number |
Effective pool mouth number |
Invalid pool mouth number |
Effective percentage |
Obvious effective rate |
Treatment |
232 |
126 |
92 |
14 |
93.97% |
54.31% |
Prevention |
28 |
22 |
5 |
1 |
96.43% |
78.57% |
* case reason of failing to respond to any medical treatment mainly contains: 1, treatment time is too late, and sick fish has a delicate constitution and do not eat food; 2, pond water quality worsens; 3, concurrent other fish diseases (as research of hemorrhage of grass carp, enteritis disease etc.).
As fully visible, the concurrent syndrome safety of Chinese herbal compound preparation of the present invention treatment Ctenopharyngodon idellus entomogenous fungi, effectively, by the associating of I type, II type medicine or be used alone, prevention or the concurrent syndrome for the treatment of Ctenopharyngodon idellus entomogenous fungi all have remarkable result.
Detailed description of the invention
Embodiment 1
A kind of Chinese herbal compound preparation preventing and treating the concurrent syndrome of Ctenopharyngodon idellus entomogenous fungi, be made up of Herba polygoni hydropiperis, Nicotiana tabacum L., Radix Et Rhizoma Rhei and Radix Artemisia ordosicae, I type medicine is by its weight parts Herba polygoni hydropiperis 35 parts, 60 parts, Nicotiana tabacum L., Radix Et Rhizoma Rhei 5 parts, and II type medicine is by its weight parts Herba polygoni hydropiperis 60 parts, 5 parts, Nicotiana tabacum L., Radix Et Rhizoma Rhei 15 parts, Radix Artemisia ordosicae 20 parts.
Its preparation method: get Herba polygoni hydropiperis, Nicotiana tabacum L., Radix Et Rhizoma Rhei, Radix Artemisia ordosicae dry rear micronizing, by the drug ratio requirement of I type, II type, by Herba polygoni hydropiperis, Nicotiana tabacum L., Radix Et Rhizoma Rhei and Radix Artemisia ordosicae powder mix homogeneously, make stock of drugs after sealing pack.
Its using method: treating medication is first that I type, II type medicine sprinkle outward, conbined usage for oral administration; I type medicine adds 10-15 times of water gaging heated and boiled 10 minutes or soaks 1 hour with the boiled water (temperature more than 90 DEG C) of 10-15 times amount, and evenly splash in the full pond that adds water after cooling, consumption is 2 g/m
3; The II type medicine boiled water (temperature more than 90 DEG C) of 3-5 times amount soaks 1 hour, and add Testa oryzae (or Testa Tritici, rapeseed cake etc.) after cooling and stir, make bait feeding, consumption is that II type medicine 50-100g mixed by every 1 kg bait; Rising next day can alone II type medicine, within 5-7 days, is a course for the treatment of.
Embodiment 2
Prevent and treat a Chinese herbal compound preparation for the concurrent syndrome of Ctenopharyngodon idellus entomogenous fungi, be made up of Herba polygoni hydropiperis, Nicotiana tabacum L., Radix Et Rhizoma Rhei and Radix Artemisia ordosicae, II type medicine is by its weight parts Herba polygoni hydropiperis 50 parts, 25 parts, Nicotiana tabacum L., Radix Et Rhizoma Rhei 10 parts, Radix Artemisia ordosicae 15 parts.
Its preparation method: with embodiment as identical.
Its using method: the boiled water (temperature more than 90 DEG C) getting II type medicine 3-5 times amount soaks 1 hour, and add Testa oryzae (or Testa Tritici, rapeseed cake etc.) after cooling and stir, make bait feeding, consumption is that II type medicine 50-100g mixed by every 1 kg bait; Make pharmaceutical chemistry with II type medicine, pharmaceutical chemistry 1-2 time of monthly throwing something and feeding, is used in conjunction 3-5 days at every turn.