CN107375552A - A kind of preventing and treating composition of bee European foul brood and preparation method thereof - Google Patents
A kind of preventing and treating composition of bee European foul brood and preparation method thereof Download PDFInfo
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- CN107375552A CN107375552A CN201710619633.4A CN201710619633A CN107375552A CN 107375552 A CN107375552 A CN 107375552A CN 201710619633 A CN201710619633 A CN 201710619633A CN 107375552 A CN107375552 A CN 107375552A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/86—Violaceae (Violet family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/19—Acanthaceae (Acanthus family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/288—Taraxacum (dandelion)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/46—Ingredients of undetermined constitution or reaction products thereof, e.g. skin, bone, milk, cotton fibre, eggshell, oxgall or plant extracts
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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Abstract
The invention discloses a kind of preventing and treating composition of bee European foul brood, including 1 ~ 5 part of 1 ~ 5 part of Chinese violet, 1 ~ 5 part of radix tarxaci and Herba Andrographitis；Comprise the following steps preparation：Step 1: crush：Chinese violet, radix tarxaci and Herba Andrographitis are crushed and fragmentated；Step 2: cleaning：Fragment is put into clear water, it is standby after cleaning；Step 3: decoct：Fragment after step 2 is cleaned is put into 75 ~ 400 times of water, and small fire obtains Traditional Chinese medicine pulp after decocting 4 ~ 5h；Step 4: mixing：By the Traditional Chinese medicine pulp of step 3 according to 1:1 ratio is mixed to get preventing and treating composition with the syrup that concentration is 60 ~ 70%.The preventing and treating composition of the bee European foul brood of the present invention, pass through Chinese violet, the combination of three kinds of Chinese medicines of radix tarxaci and Herba Andrographitis, feed metainfective honeybee 2 ~ 4 days, it can reach the purpose cured completely, cure rate is more than 95%, and time length is quick, for can not treating bee European foul brood completely compared to one-component, just there is positive meaning.
Description
Technical field
The present invention relates to bee raising technical field, and in particular to a kind of preventing and treating composition of bee European foul brood
And preparation method thereof.
Background technology
Bee European foul brood, abbreviation Europe children sick (European foulbrood, EFB) is the one of the bee larva phase
Kind of contagious disease, the small grub below the age in days of main infection 2, the disease belong to worldwide disease, the disease in 1885 first
Report, betides almost all of beekeeping state of the world extensively at present.China in early 1950s in Guangdong Province first
It was found that disease occur in succession in all provinces in south at the beginning of the sixties, then sprawling is national.Not only apis mellifera infects the disease, Eastern bee
Especially middle honeybee also easy infection, and it is much more serious than apis mellifera to infect sequela.General only infection is less than the larva of 2 ages in days,
Usual disease pest is dead in 4-5 ages in days.After illness, polypide discoloration, fat figure is lost.It is changed into faint yellow, yellow from white as pearl
It is color, light brown, or even dark brown.When just having become brown, pass through the tracheal system of the high-visible larva of epidermis.With discoloration, larva
Collapse, it appears that be twisted, finally in lair bottom rot, dry up, turn into viscosity, the scale of easy-clear.Polypide is in distress when rotting
The acid smell of news.
In face of international severe situation, the relevant rule according to OIE to animal serious infectious diseases Quarantine Techniques
It is fixed, researched to developed with reference to China's actual conditions and meet the bee European foul brood quarantine code of international rule and have become and work as
Business is anxious.As prior art CN104257784A discloses a kind of middle honeybee European foul brood preventing and treating herbal prescription.It is pressed
Mass fraction 100% is counted, and is made up of following component, and the coptis 22%~27%, selfheal 21%~25%, astragalus polyose 18%~
26%th, dandelion 18%~22% and honeysuckle 12%~16%.The middle honeybee European foul brood preventing and treating Chinese herbal medicine of the present invention
Prescription has enhancing resistance, hence it is evident that reduces the incidence of disease and disease index, promotes the development breeding of bee colony group gesture；But said preparation needs
5 kinds of raw materials are wanted, and astragalus polyose therein can only could be bought in large-scale pharmacy, the peasant household typically raised bees is put in intermountain
Support, and due to honeybee morbidity infection and dead excessive velocities, therefore if being made up a prescription by astragalus polyose, will come on the time
It is too late, cause great loss, and the cure rate of the preventing and treating herbal prescription is 80% or so, and treatment time is longer, typically exists
One week or so.
The content of the invention
In order to overcome astragalus polyose in prior art bee European foul brood preventing and treating herbal prescription to be not easy to obtain, and
A kind of the problem of composition cure rate is low, there is provided preventing and treating composition of brand-new bee European foul brood.
The technical scheme is that：A kind of preventing and treating composition of bee European foul brood, including with parts by weight
The following raw material of meter：1 ~ 5 part of 1 ~ 5 part of Chinese violet, 1 ~ 5 part of radix tarxaci and Herba Andrographitis.
As scheme it is further preferred that the parts by weight of each raw material are：2 ~ 3 parts of Chinese violet, 2 ~ 3 parts of radix tarxaci and
2 ~ 3 parts of Herba Andrographitis.
Further walked as scheme preferably, the parts by weight of each raw material are：2 parts of Chinese violet, 2 parts of radix tarxaci and punching
2 parts of lotus.
Still further preferably, the parts by weight of each raw material are：3 parts of 2 parts of Chinese violet, 3 parts of radix tarxaci and Herba Andrographitis.
The working principle and beneficial effect of the present invention：The raw material of the present invention includes three kinds of Chinese herbal medicines, Chinese violet, dandelion
Root and Herba Andrographitis, wherein Chinese violet (Viola yedoensis) are that Violaceae (Violaceae) Viola (Viola L.) is more
Year raw herbaceous plant, also known as light calyx violet, viola japonica, Bunge Corydalis Herb and Herba Violae etc., taste bitter, acrid, cold.The thoughts of returning home, lung channel.With clear
Thermal detoxification, cool blood detumescence, the effect of clearing heat and promoting diuresis, cure mainly furunculosis, carbuncle swells, scrofula, jaundice, dysentery, diarrhoea, hot eyes, larynx numbness, poison
Snake bite.Modern pharmacology research finds that it has preferable antiviral, anti-inflammatory, antibacterial and antitumor activity.Clinically use
In treatment furuncle swelling toxin, urinary tract infections, cellulitis, mammitis, pharyngitis, dysentery, jaundice, red eye, swell pain etc..
Dandelion is called " grandmother's fourth ", Chinese violet, sowthistle-leaf ixeris seedling, and Dandelion composite family perennial herb thing is planted, dandelion bitter,
It is sweet, it is cold in nature, have clearing heat and detoxicating, inducing diuresis to remove edema, dissipating bind disappear carbuncle the effect of.Modern chemical analysis shows that radix tarxaci is public containing Pu
The Multiple components such as English alcohol, dandelion match acid, β-amyrin, stigmasterol, choline, organic acid, glycoside.Modern pharmacological research
Also indicate that, dandelion has broad-spectrum antibacterial action, has certain inhibitory action for Escherichia coli, staphylococcus etc..It also has
Antitumor, liver protection, cholagogic, antiendotoxin and diuresis, it can be with the guarantor of the immunocompetence of excitating organism, especially dandelion
Liver effect is very strong.Clinically, dandelion can treat acute mastitis, adenolymphitis, scrofula, boil poisonous soreness, acute conjunctiva
Inflammation, cold, fever, acute tonsillitis, acute bronchitis, gastritis, hepatitis, cholecystitis, urinary tract infections, osteomyelitis etc. are a variety of
Illness.
Herba Andrographitis, also known as Chun Lianqiuliu, Banlangen, Euphorbia, andrographis paniculata, golden vanilla, golden tack, India's grass, eel grass etc.,
For acanthaceous plant Herba Andrographitis Andrographis Paniculata (Burm.f.) Nees dry aerial parts.Originate in print
There is cultivation in degree, the area such as China East China, Central-South.Property it is bitter, tremble with fear, the thoughts of returning home, lung, large intestine, bladder warp.With clearing heat and detoxicating, cool blood,
Swelling and pain relieving and other effects.Clinic is mainly used in cold, fever, abscess of throat, aphthae, pertussis overstrain cough, dysentery, heat gonorrhea
The diseases such as puckery pain, carbuncle swells sore, venomous snake bite.
The preventing and treating composition of the bee European foul brood of the present invention, passes through Chinese violet, radix tarxaci and Herba Andrographitis
The combination of three kinds of Chinese medicines, wherein, Chinese violet is monarch drug in a prescription, and dandelion is ministerial drug, and Herba Andrographitis is to make medicine, based on monarch drug in a prescription, ministerial drug
With make supplemented by medicine, the taraxol contained in radix tarxaci and dandelion match acid and the andrographolide contained in Herba Andrographitis are effective
Strengthen sterilization, anti-inflammatory and the antiphlogistic effects of flavones and its glycoside in Chinese violet, feed metainfective honeybee 2 ~ 4 days, you can reach
To the purpose cured completely, cure rate is more than 95%, and time length is quick, and honeybee can not be treated completely compared to one-component
For European foul brood, just there is positive meaning.
The preparation method of the preventing and treating composition of bee European foul brood, comprises the following steps：
Step 1: crush：Chinese violet, radix tarxaci and Herba Andrographitis are collected, crushes fragmentate in proportion；
Step 2: cleaning：The fragment of step 1 is put into clear water, it is standby after cleaning；
Step 3: decoct：Fragment after step 2 is cleaned is put into 75 ~ 80 times of water, and small fire obtains Chinese medicine after decocting 4 ~ 5h
Slurry；
Step 4: mixing：By the Traditional Chinese medicine pulp of step 3 according to 1:3 ratio is mixed to get preventing and treating with the syrup that concentration is 60 ~ 70%
Composition.
Preferable as scheme, the syrup is hydromel.
The beneficial effect of the inventive method：The preparation method of the present invention by the way that the Chinese medicine of three kinds of scientific compatibilities is decocted,
It is mixed to prepare to the preventing and treating composition of bee European foul brood with syrup again, this method is simple and easily operated, simultaneously
Small fire, which decocts, makes the drug effect of medicinal material slowly discharge, and is dissolved in composition, the beneficiating ingredient in composition is merged into each other and is wrapped
Cover, after being mixed with syrup by medicine slurry parcel wherein, reduce the bitter taste of composition, increase its palatability, so as to supplement infection honey
Nutriment and the property of medicine needed for honeybee, and then play maximum drug effect.
Further, the Chinese violet, radix tarxaci and Herba Andrographitis before crushing first will processing 20 at -10 ~ -5 DEG C ~
30min.Chinese medicine freezing processing, is first influenceed into composition to honeybee at destruction when avoiding crushing to drug ingedient before crushing
The therapeutic effect of European foul brood.
Embodiment
The technical method of the present invention is described in detail with reference to specific embodiment：
The composition material proportioning of the present invention is as shown in the table：
Note：1 part is 10g.
To prepare embodiment 1 to illustrate, comprise the following steps：
Step 1: crush：20g Chinese violet, 20g radix tarxaci and 20g Herba Andrographitis is collected, is freezed at -10 ~ -5 DEG C
30min, crushing fragmentate；
Step 2: cleaning：The fragment of step 1 is put into clear water, it is standby after cleaning；
Step 3: decoct：The decocting of fragment and 1450g after step 2 is cleaned is cooked into Traditional Chinese medicine pulp：
Step 4: mixing：The hydromel of the Traditional Chinese medicine pulp of step 3 and 3000g is mixed to get the anti-of bee European foul brood
Control composition.
Experimental verification：The composition of 1 ~ embodiment of the embodiment of the present invention 4 is arranged to experimental group, the hydromel of same concentration
For blank control group, CN104257784A composition is the control group of prior art, is fed at dusk, every by this dosage
It is secondary to feed the frame honeybee of honeybee 10 ~ 15, the drinking-water of cleaning is arranged on around bee farm during feeding, continuous feeding 2 days, observes and draw following table：
As can be seen from the table, only feeding hydromel, for cure rate 10% or so, the ratio is the recovery from illness of honeybee itself resistance,
It is that can not treat bee European foul brood that pure hydromel, which can be drawn, is compared with the prior art, embodiments of the invention 1
~ 4 treatment time is respectively less than prior art, while its cure rate is also far above prior art, therefore the composition of the present invention is more
Meets the needs of beekeeper.
Above-described is only embodiments of the invention, and the general knowledge such as known concrete structure and characteristic is not made herein in scheme
Excessive description., without departing from the structure of the invention, can be with it should be pointed out that for those skilled in the art
Several modifications and improvements are made, these should also be considered as protection scope of the present invention, and these are implemented all without the influence present invention
Effect and practical applicability.The scope of protection required by this application should be based on the content of the claims, in specification
The records such as embodiment can be used for the content for explaining claim.
Claims (7)
- A kind of 1. preventing and treating composition of bee European foul brood, it is characterised in that：Including the following original in terms of parts by weight Material：1 ~ 5 part of 1 ~ 5 part of Chinese violet, 1 ~ 5 part of radix tarxaci and Herba Andrographitis.
- 2. the preventing and treating composition of bee European foul brood according to claim 1, it is characterised in that the weight of each raw material Measuring number is：2 ~ 3 parts of 2 ~ 3 parts of Chinese violet, 2 ~ 3 parts of radix tarxaci and Herba Andrographitis.
- 3. the preventing and treating composition of bee European foul brood according to claim 1, it is characterised in that the weight of each raw material Measuring number is：2 parts of 2 parts of Chinese violet, 2 parts of radix tarxaci and Herba Andrographitis.
- 4. the preventing and treating composition of bee European foul brood according to claim 1, it is characterised in that the weight of each raw material Measuring number is：3 parts of 2 parts of Chinese violet, 3 parts of radix tarxaci and Herba Andrographitis.
- 5. according to the preparation method of the preventing and treating composition of any described bee European foul brood of claim 1 ~ 4, it is special Sign is, comprises the following steps：Step 1: crush：Chinese violet, radix tarxaci and Herba Andrographitis are collected, crushes fragmentate in proportion；Step 2: cleaning：The fragment of step 1 is put into clear water, it is standby after cleaning；Step 3: decoct：Fragment after step 2 is cleaned is put into 75 ~ 400 times of water, and small fire obtains Chinese medicine after decocting 4 ~ 5h Slurry；Step 4: mixing：By the Traditional Chinese medicine pulp of step 3 according to 1:3 ratio is mixed to get preventing and treating with the syrup that concentration is 60 ~ 70% Composition.
- 6. the preparation method of the preventing and treating composition of bee European foul brood according to claim 5, it is characterised in that The syrup is hydromel.
- 7. the preparation method of the preventing and treating composition of bee European foul brood according to claim 6, it is characterised in that The Chinese violet, radix tarxaci and Herba Andrographitis first will handle 20 ~ 30min before crushing at -10 ~ -5 DEG C.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710619633.4A CN107375552A (en) | 2017-07-26 | 2017-07-26 | A kind of preventing and treating composition of bee European foul brood and preparation method thereof |
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| CN201710619633.4A CN107375552A (en) | 2017-07-26 | 2017-07-26 | A kind of preventing and treating composition of bee European foul brood and preparation method thereof |
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| CN107375552A true CN107375552A (en) | 2017-11-24 |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107714986A (en) * | 2017-11-27 | 2018-02-23 | 安徽省甘泉养蜂专业合作社 | A kind of protective agents of Chinese honeybee European foul brood and preparation method thereof |
| CN109045134A (en) * | 2018-09-20 | 2018-12-21 | 中国农业科学院蜜蜂研究所 | Application of the madder in prevention and treatment Bee venoms |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104257784A (en) * | 2014-09-25 | 2015-01-07 | 广东省昆虫研究所 | Chinese herbal medicine formula for preventing and treating European foul brood of Apis cerana |
-
2017
- 2017-07-26 CN CN201710619633.4A patent/CN107375552A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104257784A (en) * | 2014-09-25 | 2015-01-07 | 广东省昆虫研究所 | Chinese herbal medicine formula for preventing and treating European foul brood of Apis cerana |
Non-Patent Citations (1)
| Title |
|---|
| 杨冠煌: "《中华蜜蜂的保护和利用》", 31 August 2013, 北京：科学技术文献出版社 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107714986A (en) * | 2017-11-27 | 2018-02-23 | 安徽省甘泉养蜂专业合作社 | A kind of protective agents of Chinese honeybee European foul brood and preparation method thereof |
| CN109045134A (en) * | 2018-09-20 | 2018-12-21 | 中国农业科学院蜜蜂研究所 | Application of the madder in prevention and treatment Bee venoms |
| CN109045134B (en) * | 2018-09-20 | 2021-05-28 | 中国农业科学院蜜蜂研究所 | Application of madder in preventing and treating bee-brood cocci |
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