CN108096434B

CN108096434B - Plant additive for pig feed and preparation method and application thereof

Info

Publication number: CN108096434B
Application number: CN201711270235.2A
Authority: CN
Inventors: 廖海标; 李城丰
Original assignee: Guangzhou Baiyunshan Baoshen Animal Health Products Co ltd
Current assignee: Guangzhou Baiyunshan Baoshen Animal Health Products Co ltd
Priority date: 2017-12-05
Filing date: 2017-12-05
Publication date: 2021-03-12
Anticipated expiration: 2037-12-05
Also published as: CN108096434A

Abstract

The invention discloses a plant additive for pig feed and a preparation method and application thereof, and belongs to the technical field of feed additives. In order to eliminate the common immunosuppression problem of the swinery and further improve and enhance the vaccine immune effect. The invention discloses a plant additive of pig feed, which comprises the following raw materials in parts by weight: 1-60 parts of honeysuckle, 1-45 parts of houttuynia cordata, 1-60 parts of rhizoma anemarrhenae, 1-45 parts of red paeony root, 6-45 parts of cortex lycii radicis, 5-60 parts of astragalus membranaceus, 5-60 parts of bighead atractylodes rhizome, 5-60 parts of codonopsis pilosula, 5-60 parts of radix paeoniae alba, 1-60 parts of angelica sinensis, 1-90 parts of polygonum multiflorum, 1-60 parts of rhizoma cyperi, 6-60 parts of orange peel, 4-60 parts of fructus aurantii, 1-40 parts of trifoliate orange stems and 1-60 parts of liquorice. The plant additive of the pig feed can eliminate the common immunosuppression problem of the swinery, enhance the immune function of the swinery, improve the disease resistance of the organism, and enable the swinery to be in a healthy state, so as to achieve the purpose of further improving and enhancing the vaccine immune effect.

Description

Plant additive for pig feed and preparation method and application thereof

Technical Field

The invention relates to the technical field of feed additives, in particular to a plant additive for pig feed and a preparation method and application thereof.

Background

The pig industry is the traditional industry in China and has a long history of six to seven thousand years. For over half a century, the pig industry in China has drawn attention. According to statistics, the number of live pigs in stock is 4.74 hundred million and the number of live pigs in stock is 7.16 hundred million in 2013, which accounts for more than half of the total number of pigs raised all over the world and becomes the first major country for pork production and consumption. However, as the pig raising production mode gradually develops from the traditional decentralized mode to the modernization, intensification, standardization, scale and intellectualization direction, the technical level of the whole pig raising in China at present is far from the difference of the national areas developed in Europe and America. Therefore, the pig raising production in China is only one pig raising production and consumption country, and is not a pig raising strong country.

According to the data, the region in the middle of Europe in Germany has the territorial area of 35.7 ten thousand square kilometers and the population 8220 ten thousand, which is the country with the highest economic development level in Europe. Half of the land in the country is used for agricultural production, mainly raising pigs, cattle and sheep and also used in the nutrition and planting industry. The German pig raising is the third pig raising country following China and the United states, the pig raising production mode is moderate large-scale production and operation mainly based on family farms, and more than 25 weaned live Piglets (PSY) can be provided for breeding sows every year on average. Danish is a typical agricultural country, a country with only 4.3 million square kilometers and over 500 million people, and 225 people live and consume with less than 4% of the total population of agricultural workers. The danish animal husbandry is well developed, and particularly, the pig raising technology is ahead of the world. For example, about 100 million sows are kept in the Danish market in 2014, 3000 million commercial pigs are sold in the market every year, 30 weaned live Piglets (PSY) can be provided for each sow in average every year, and the PSY in China is only 18, which is 60 percent of the production score of Danish.

According to analysis, the reason for causing the great difference between the pig raising production in China and the foreign countries or regions developed in Europe and America is that: the main reasons of the method are low epidemic disease prevention and control level and poor follow-up except for variety, feed, climate, personnel quality, management level, market and other factors. On one hand, the concept of preventing and treating animal epidemic diseases is old, the prevention and treatment technology is backward, and the overall technical level and quality of veterinarians are not high; the other side is that the current swine herd immunosuppression problem is ubiquitous. When the pig herd is attacked, the problems of secondary infection of various pathogens, virus strain variation, enhanced drug resistance of bacteria and the like are mainly presented, so that clinical pathogen diversification and complicated disease symptoms are presented, and great difficulty is brought to diagnosis and treatment of the pig diseases. Therefore, currently, prevention and control of swine diseases urgently need to be carried out on swine fever, porcine reproductive and respiratory syndrome (PRRS, commonly called porcine reproductive and respiratory syndrome, blue ear for short), porcine circovirus type 2 (PCV2, circular ring for short) and other porcine viral diseases so as to eliminate the common problem of immunosuppression of swine herds, enhance the immune function of the swine herds, improve the antibody level of vaccines, enhance the infection capacity of organisms against viruses, germs and the like, and achieve good prevention and control effects.

Disclosure of Invention

The invention aims to provide the plant additive of the pig feed, which can prevent and treat various virus diseases of pigs, enhance the immune function of the pigs, improve the disease resistance of organisms, eliminate the common problem of immunosuppression of swinery and further improve and enhance the immune effect of vaccines.

The invention also aims to provide a specific preparation method of the plant additive of the pig feed.

The invention also aims to provide the application of the plant additive of the pig feed.

The invention is suitable for all growth stages of the domestic livestock, including a young stage, a growth stage and a breeding stage.

The invention is realized by the following technical scheme: a plant additive for pig feed comprises the following raw materials in parts by weight:

1-60 parts of honeysuckle, 1-45 parts of houttuynia cordata, 1-60 parts of rhizoma anemarrhenae, 1-45 parts of red paeony root, 6-45 parts of cortex lycii radicis, 5-60 parts of astragalus membranaceus, 5-60 parts of bighead atractylodes rhizome, 5-60 parts of codonopsis pilosula, 5-60 parts of radix paeoniae alba, 1-60 parts of angelica sinensis, 1-90 parts of polygonum multiflorum, 1-60 parts of rhizoma cyperi, 6-60 parts of orange peel, 4-60 parts of fructus aurantii, 1-40 parts of trifoliate orange stems and 1-60 parts of liquorice.

The traditional Chinese medicines are all commonly used in clinic, the medicine parts of the traditional Chinese medicines are all well known by technical personnel in the field, and the plant additive of the pig feed can prevent and treat viral diseases such as porcine reproductive and respiratory syndrome, swine fever, porcine circovirus disease and the like, can improve the meat quality and flavor of pork, and can improve the commercial value of the pork. According to the prevention and treatment effect of the traditional Chinese medicine composition on the pig diseases, the inventor prefers on the basis of the traditional Chinese medicine composition, and the traditional Chinese medicine composition is prepared from the following raw materials in parts by weight:

12 parts of honeysuckle, 12 parts of houttuynia cordata, 15 parts of rhizoma anemarrhenae, 15 parts of red peony root, 15 parts of cortex lycii radicis, 20 parts of astragalus membranaceus, 15 parts of bighead atractylodes rhizome, 20 parts of codonopsis pilosula, 15 parts of radix paeoniae alba, 15 parts of angelica sinensis, 15 parts of polygonum multiflorum, 15 parts of rhizoma cyperi, 10 parts of orange peel, 12 parts of fructus aurantii, 10 parts of poncirus trifoliata stems and 15 parts of liquorice.

The natural medicinal plant contains various organic components including medicinal effective components such as alkaloid, glycoside, terpenoid, tannin, organic acids and volatile oil, and nutritional components (medicinal ineffective components) such as saccharide, protein, amino acid and inorganic salt. The saccharides in turn comprise monosaccharides, oligosaccharides and polysaccharides. Polysaccharides commonly found in natural plants include starch, cellulose, mucilaginous matter, pectin, gum, inulin, chitin, and the like, which have been considered to be biologically inactive and are generally removed as impurities. In modern biological science research, polysaccharides mainly affect the reticuloendothelial system, macrophages, lymphocytes, leukocytes, RNA, DNA, protein synthesis, antibody production, cAMP and cGMP content, complement production to induce interferon, and the like. Therefore, the polysaccharide is an immunopotentiator, and can enhance the immune function of the organism and improve the disease resistance. The main chemical components and the pharmacology of the traditional Chinese medicine are as follows:

honeysuckle flower: the main components comprise volatile oil (linalool, cis-linalool oxide, eugenol, carvacrol, etc.), chlorogenic acid, isochlorogenic acid, ginkgolic acid, etc. Sweet in nature and taste and cold in nature. Enters lung, stomach and large intestine meridians. Clearing away heat and toxic material.

Houttuynia cordata: the main components are saccharide, protein, fat, crude fiber, ascorbic acid, etc. Pungent and cool in nature and taste. Enter the lung meridian. Clearing away heat and toxic material.

Rhizoma anemarrhenae: the main components comprise various steroid saponins, flavonoid glycosides and the like. Bitter, sweet and cold in nature. Enter lung, stomach and kidney meridians. Clear heat and reduce fire, nourish yin and moisten dryness.

Red peony root: the main components comprise paeoniflorin, benzoylpaeoniflorin, alkaloid, etc. Bitter in property and slightly cold in nature. Enter liver and spleen meridians. Clear heat and cool blood, dispel stasis and alleviate pain.

Cortex lycii radicis: the main components comprise betaine, B-sitosterol, linoleic acid, cinnamic acid, various phenols and the like. Sweet, bland and cold in nature and taste. Enter lung, liver and kidney meridians. Cool blood, relieve steaming, clear lung-heat and purge fire.

Astragalus root: the main components comprise astragalus polysaccharide, alkaloid, nicotinic acid, nicotinoyl acid and the like. Sweet in nature and taste, slightly warm. Enter spleen and lung meridians. Tonify middle-jiao and Qi, strengthen superficies, check sweating, induce diuresis to alleviate edema, support sores and discharge pus.

White atractylodes rhizome: the main ingredients comprise volatile oil (atractylenolide, eucalyptol, and atractylenol), atractylenolide, and scopoletin. Sweet in nature, bitter and warm in taste. Enter spleen and stomach meridians. Tonify spleen and qi, dry dampness and induce diuresis, strengthen superficies to check sweating.

Codonopsis pilosula: the main components comprise saponin, alkaloid, etc. Sweet in nature and taste and mild in nature. Enter spleen and lung meridians. Tonify middle warmer, replenish qi, and promote fluid production.

White peony root: the main components comprise paeoniflorin, hydroxy paeoniflorin, albiflorin, etc. Bitter, sour and slightly cold in nature. Enter liver meridian. Nourish blood and astringe yin, soften liver and alleviate pain.

Chinese angelica: the main components comprise volatile oil (ligustilide, etc.), fatty oil, palmitic acid, etc. Sweet in nature, pungent and warm in flavor. Enter heart, liver and spleen meridians. Enrich blood and nourish blood, activate blood and alleviate pain, moisten intestines to relieve constipation.

Polygonum multiflorum: the main components comprise anthraquinone (chrysophanol, emodin, etc.), starch, crude fat, lecithin, etc. Sweet, bitter and astringent in nature and taste, and slightly warm. Enter heart, liver and kidney meridians. He shou Wu tonifies liver and kidney, and benefits essence and blood. The prescription is prepared from 1-90 parts of fleece-flower root.

Rhizoma cyperi: the main ingredient rhizome contains patchouli ketene, cyperolone, volatile oil, etc. Pungent, slightly bitter, slightly sweet and mild in nature. Enter liver, spleen and triple energizer meridians. Regulate qi, relieve depression, dissipate stagnation and alleviate pain.

Orange peel: mainly contains volatile oil (limonene, etc.), flavone sweet (hesperidin, etc.), nobilene, etc. Pungent, bitter and warm in nature. Enter spleen and lung meridians. Regulate qi to invigorate spleen, dry dampness and resolve phlegm.

Fructus aurantii: mainly contains volatile oil, hesperidin, etc. Bitter in property and slightly cold in nature. Enter spleen and stomach meridians. Breaking qi and removing food retention.

Balloon flower: the main component contains saponin, etc. Bitter, pungent and mild in nature. Enter the lung meridian. Disperse lung qi to stop cough, clear throat and relieve sore throat, dispel phlegm and expel pus.

Licorice root: the main components comprise liquiritigenin, multiple flavones, etc. Sweet in nature and taste and mild in nature. Enter heart, lung, spleen and stomach meridians. Tonify spleen and qi, moisten lung and relieve cough, clear heat and remove toxicity, and harmonize property of the drugs.

In order to further improve the function and the effect of the formula, 1 to 120 portions of gypsum with the moisture content not more than 8 percent and 500 portions of sodium humate 150-. Specifically, the gypsum is 30 parts, and the sodium humate is 391.5 parts.

Gypsum is the sulfate mineral Gypsum, is widely distributed, is mainly produced in Hubei, Gansu, Sichuan and other places, and is preferably produced in Hubei and Anhui. After digging out, remove soil and miscellaneous stones, and crush them, unprocessed. The main component is calcium sulfate, etc. Pungent, sweet and cold in nature. Enter lung and stomach meridians. Clear heat and purge fire, astringe and promote granulation.

The sodium humate is obtained by pulverizing peat, brown coal or weathered coal, reacting with sodium hydroxide solution to obtain supernatant, concentrating, and drying, or further refining by granulating, wherein the content of soluble humic acid is not less than 55%, and the content of water is not more than 12%. The natural mineral humic acid is mainly a product obtained by chemically and microbially degrading organic matters in animal and plant remains, and mainly comprises polysaccharides, proteins, amino acids, alkaloids, terpenes, steroids, inorganic minerals and other compounds. The functional group of humic acid mainly comprises carboxyl, phenolic hydroxyl, quinonyl, and then-OH, -OCH 3, non-quinonyl, amino and other multifunctional groups. Therefore, humic acid contains various bioactive substances and has wide biological functions and pharmacological actions of enhancing immunity, resisting virus, bacteria, fungi and the like.

The plant additive of the pig feed provided by the invention is powder and granules.

The preparation method of the plant additive of the pig feed comprises the following steps:

(1) accurately weighing raw traditional Chinese medicinal materials which are processed and have impurities removed according to the weight part ratio of the formula;

(2) respectively micronizing the Chinese medicinal materials, and sieving with 80-120 mesh sieve;

(3) dividing the Chinese medicinal materials into 3-5 groups according to the proportion weight, and dividing the Chinese medicinal materials with the same or similar parts by weight into one group, wherein each group contains 2-8 parts of Chinese medicinal material powder;

(4) respectively mixing the grouped traditional Chinese medicine powder to obtain the traditional Chinese medicine premixed powder of each group;

(5) micronizing gypsum, and sieving with 80-120 mesh sieve;

(6) preparing sodium humate, carrying out superfine grinding on the sodium humate, and sieving the sodium humate by a sieve of 80-120 meshes;

(7) weighing 30 parts of gypsum powder and 391.5 parts of sodium humate powder, and mixing and stirring the gypsum powder and the 391.5 parts of sodium humate powder for 15-20 minutes to obtain a mixed material;

(8) adding the premixed powder of the Chinese medicinal materials into the mixed material prepared in the step (7) according to the weight parts, wherein when the premixed powder of the Chinese medicinal materials is added, the stirring is carried out for 5-6 minutes, and when the premixed powder of the last group of the Chinese medicinal materials is added, the stirring is carried out for 10-15 minutes, so as to obtain a semi-finished product;

(9) adjusting the uniformity and the moisture of the semi-finished product to ensure that the uniformity CV is less than or equal to 5 percent and the moisture content is less than or equal to 10 percent to obtain a finished powder product; or adjusting the granularity of the semi-finished product according to the requirement to prepare a finished granule product.

According to the raw material proportion and the technical requirements of the production process of the product, qualified and high-quality traditional Chinese medicinal materials are selected. The specific requirements for each raw material component are as follows:

honeysuckle flower: is dried flower bud of Lonicera japonica Thunb. Produced in most areas of the country.

Houttuynia cordata: is whole plant of Houttuynia cordata Thunb of Saururaceae. The plants can be harvested when the flowers bloom in the same year. The next year, the corn can be harvested 2 times. Cutting stem and leaf, cleaning, removing root, and fresh or sun drying.

Rhizoma anemarrhenae: is dried rhizome of Anemarrhena asphodeloides bge. Collected in spring and autumn, removed stem and root, dried in the sun to obtain rhizoma anemarrhenae; rhizoma anemarrhenae meat is obtained by peeling off the outer skin and drying in the sun. Sliced, unprocessed, stir-baked with salt or wine.

Red peony root: is root of Paeonia lactiflora Pall (wild), Paeonia herbacea P.obovataMaxim. or Paeonia veitchii Lynch. Collected in autumn, removed stems, reed heads and fibrous roots, scraped to remove rough skin and dried in the sun. Sliced and unprocessed.

Cortex lycii radicis: is dried root bark of Lycium chinense Mill or Lycium barbarum L of Lycium of Solanaceae. Is distributed in the north and south of China. Collected in early spring or after autumn, stripped off root bark, dried in the sun, and cut into pieces.

Astragalus root: is root of Astragalus membranaceus Bge Astragalus membranaceus (Fisch.) Bge. of Leguminosae and Astragalus membranaceus Bge. Var. mongholicus (Bge.) Hsiao. Collected in spring and autumn, and collected in autumn with better quality. Removing aerial parts and fibrous roots, and sun drying. And (6) moistening and slicing. Unprocessed or stir-baked with honey.

White atractylodes rhizome: is dried rhizome of Atractylodes macrocephala Koidz of Compositae. Collected in autumn, cleaned soil and overground part, dried in the sun or baked. The soft slices are soaked in water. Unprocessed or stir-baked with bran.

Codonopsis pilosula: is dried root of Codonopsis pilosula Codonopsis (Franch.) Nannf. Collected in spring and autumn, preferably in autumn. Digging out root, removing silt and stem seedling, sun drying while rubbing to make bark part tightly contact with xylem part, sun drying, and cutting.

White peony root: is dried root of Paeonia lactiflora pall. Collected in summer and autumn, cleaned soil and fibrous root, peeled, soaked in boiling water or slightly boiled until heated uniformly, and dried in the sun. Sliced, unprocessed, stir-baked with wine or stir-baked.

Chinese angelica: is dried root of Angelica sinensis (Oliv) Diels) belonging to Umbelliferae. Collected in late autumn, removed fibrous root and silt, bundled into small handle after water is slightly evaporated, and smoked by slow fire or sulfur smoke. Divided into head, body and tail, sliced, unprocessed or stir-baked with wine.

Polygonum multiflorum: is dried root tuber of Polygonum multiflorum Thunb of Polygonaceae. The product is produced in most areas of the country. Digging root tuber of stem and leaf when withered or before sprouting at the end of the next year after autumn, cleaning, slicing, and drying in the sun or slightly drying to obtain radix Polygoni Multiflori; if the black bean is boiled and steamed, the black bean becomes black after being dried in the sun, and the black bean is called the tuber fleeceflower root.

Rhizoma cyperi: is dried tuber of Cyperus rotundus L. of Cyperaceae family of perennial herbaceous plant Cyperus rotundus L. Unprocessed, stir-baked with vinegar or stir-baked to charcoal. Its root and stem are attached continuously and can be made into perfume, so its name is. The distribution is very wide in China and the yield is very large. Harvesting in 9-10 months per year, digging out rhizome, washing, drying in the sun, and burning off fibrous root. Unprocessed, stir-baked with vinegar or stir-baked to charcoal.

Orange peel: is mature pericarp of citrus reticulata blanco, citrus reticulata. Mainly produced in the south provinces of the Yangtze river.

Fructus aurantii: is a nearly ripe fruit of the rutaceae plant Citrus aurantium, Citus aurantium L. and Citrus tamaka, Wilsonii tanaka. Harvesting every 9-10 months, removing pulp, flattening, and slicing. Unprocessed or stir-baked with wheat.

Balloon flower: is dried root of Platycodon grandiflorus (Jacq) A.D.C. Collected in spring and autumn, preferably in autumn. Removing seedling stem, cleaning, removing embolus, sun drying, and slicing.

Licorice root: is dried rhizome of Glycyrrhiza uralensis Fisch. Collected in autumn, cleaned, cut into sections of appropriate length, sun-dried to half dry, bundled into small bundles, and sun-dried to full dryness. Sliced, unprocessed or stir-baked with honey.

In order to better implement the preparation method of the present invention, further, the time for premixing the herbal powders in each group in the step (4) is 5 to 15 minutes.

In order to better realize the preparation method of the invention, the step (6) of preparing the sodium humate is to crush peat, brown coal or weathered coal, and then fully react with sodium hydroxide solution to obtain supernatant, and then the supernatant is concentrated and dried to obtain a finished product, or the finished product is further refined by granulation and other processes, wherein the soluble humic acid is not less than 55 percent, and the water content is not more than 12 percent.

The plant additive of the pig feed is applied to preparing medicaments for preventing and treating porcine viral diseases such as porcine reproductive and respiratory syndrome, swine plague and the like, and high fever mixed feeling syndrome of pigs. The porcine virus disease is a porcine virus disease caused by single or mixed infection of porcine circovirus disease, porcine reproductive and respiratory syndrome and swine fever; the swine high fever mixed infection syndrome is a swine high fever mixed infection disease caused by virus, mycoplasma or bacteria mixed infection.

The plant additive of the pig feed is applied to preparing the medicine for eliminating the pig herd immunosuppression.

Compared with the prior art, the invention has the following advantages and beneficial effects:

(1) the plant additive of the pig feed can eliminate the common immunosuppression problem of the swinery, enhance the immune function of the swinery, improve the disease resistance of an organism and enable the swinery to be in a healthy state, thereby realizing the enhancement of the immune effect of the vaccine;

(2) the plant additive of the pig feed can prevent various pig diseases, has a remarkable prevention effect, ensures higher survival rate of piglets, greatly reduces economic loss of pig raising merchants caused by the pig diseases, and ensures the economic benefit of the merchants for raising pigs;

(3) the plant additive of the pig feed can also play a role in treating some pig diseases, is combined with the theory of traditional Chinese medicine and western medicine, takes the latest culture concept of 'green, organic, safe and pollution-free' as guidance, and is used for dispensing medicine components, wherein the components contain multiple medicine components, have multiple action targets, and have the advantages of quick response, long action time, no toxic or side effect and no drug resistance compared with the existing traditional Chinese medicine, so that a good safety guarantee is provided for the food safety of raising livestock;

(4) the plant additive of the pig feed disclosed by the invention can promote the growth of piglets to a certain extent, reduce the daily feed consumption, improve the meat-feed ratio, further improve the economic benefit of pig raising merchants, and is suitable for being widely popularized and applied to the pig breeding industry.

Detailed Description

The present invention will be described in further detail with reference to examples, but the embodiments of the present invention are not limited thereto, and various substitutions and alterations can be made without departing from the technical idea of the present invention as described above, according to the common technical knowledge and the conventional means in the field.

The present invention will be described in further detail with reference to the following examples for the purpose of making clear the objects, process conditions and advantages of the present invention, which are given by way of illustration only and are not intended to be limiting of the present invention.

Example 1:

the embodiment discloses a plant additive of pig feed, which comprises the following raw materials in parts by weight:

12 parts of honeysuckle, 12 parts of houttuynia cordata, 15 parts of rhizoma anemarrhenae, 15 parts of red peony root, 15 parts of cortex lycii radicis, 20 parts of astragalus membranaceus, 15 parts of bighead atractylodes rhizome, 20 parts of codonopsis pilosula, 15 parts of white paeony root, 15 parts of angelica sinensis, 15 parts of polygonum multiflorum, 15 parts of rhizoma cyperi, 10 parts of orange peel, 12 parts of fructus aurantii, 10 parts of poncirus trifoliata stems, 15 parts of liquorice, 30 parts of gypsum and 391.5 parts of sodium humate.

The preparation method comprises the following steps:

(5) micronizing gypsum, and sieving with 80-120 mesh sieve;

Example 2:

1 part of honeysuckle, 1 part of heartleaf houttuynia herb, 1 part of common anemarrhena rhizome, 11 parts of red paeony root, 6 parts of cortex lycii radicis, 5 parts of astragalus, 5 parts of largehead atractylodes rhizome, 5 parts of codonopsis pilosula, 5 parts of white paeony root, 1 part of Chinese angelica, 1 part of tuber fleeceflower root, 1 part of nutgrass galingale rhizome, 6 parts of orange peel, 4 parts of bitter orange, 1 part of trifoliate orange stem, 1 part of liquoric root, 1 part of gypsum and 98.

The preparation method is the same as that of example 1.

Example 3:

60 parts of honeysuckle, 45 parts of houttuynia cordata, 60 parts of rhizoma anemarrhenae, 45 parts of red paeony root, 45 parts of cortex lycii radicis, 60 parts of astragalus mongholicus, 60 parts of bighead atractylodes rhizome, 60 parts of codonopsis pilosula, 60 parts of white paeony root, 60 parts of angelica sinensis, 90 parts of polygonum multiflorum, 60 parts of rhizoma cyperi, 60 parts of orange peel, 60 parts of fructus aurantii, 40 parts of hovenia dulcis stems, 60 parts of liquorice, 120 parts of gypsum and 185 parts of sodium humate.

The preparation method is the same as that of example 1.

Example 4:

30 parts of honeysuckle, 22 parts of houttuynia cordata, 28 parts of rhizoma anemarrhenae, 21 parts of red paeony root, 31 parts of cortex lycii radicis, 30 parts of astragalus mongholicus, 30 parts of bighead atractylodes rhizome, 30 parts of codonopsis pilosula, 30 parts of white paeony root, 35 parts of angelica sinensis, 68 parts of polygonum multiflorum, 32 parts of rhizoma cyperi, 35 parts of orange peel, 35 parts of fructus aurantii, 25 parts of hovenia dulcis stems, 35 parts of liquorice, 20 parts of gypsum and 760.5 parts of sodium humate.

The preparation method is the same as that of example 1.

Example 5:

48 parts of honeysuckle, 30 parts of houttuynia cordata, 50 parts of rhizoma anemarrhenae, 37 parts of red peony root, 34 parts of cortex lycii radicis, 45 parts of astragalus membranaceus, 45 parts of bighead atractylodes rhizome, 45 parts of codonopsis pilosula, 45 parts of white paeony root, 35 parts of angelica sinensis, 75 parts of polygonum multiflorum, 25 parts of rhizoma cyperi, 35 parts of orange peel, 34 parts of fructus aurantii, 20 parts of hovenia dulcis stem, 35 parts of liquorice, 50 parts of gypsum and 814 parts of sodium humate.

The preparation method is the same as that of example 1.

Example 6:

this example provides a toxicology test of a plant supplement for this pig feed, as follows:

acute toxicity test:

in the experimental observation, the maximum dose was measured because LD50 could not be detected. The pig feed plant additive prepared in example 1 was dissolved in sterilized normal saline to prepare a solution, and then the solution was administered to a mouse by gavage, and the results showed that the maximum administration concentration of the drug was 10.65 crude drug/ml, and the maximum administration volume was 50ml/kg, and the drug was administered twice to the mouse in 24 hours, and the maximum administration amount of the mouse was 683.25g crude drug/kg, and no adverse reaction or death occurred in the animal, and no abnormality occurred in each organ by anatomical observation.

Long-term toxicity test:

in the experiment, 200 SD rats are used, the pig feed plant additive prepared in example 1 is dissolved in sterilized normal saline to prepare a solution for intragastric administration, and the influence of the pig feed plant additive on each index of animals is observed by continuously intragastric administration for 12 weeks by setting a control group and 14g, 25g and 39g crude drug/kg dose groups. Test results show that the pig feed plant additive has no obvious influence on the weight, the food intake, the peripheral hemogram, the blood coagulation time, the electrocardiogram, the organ index and the like of a rat after continuous administration for 12 weeks; the results of twelve blood biochemical index measurements show that the BiLi value of the low-dose group after 12 weeks of administration is higher than that of the control group (P < 0.05); the TP value of the low-dose group and the medium-dose group is higher than that of the control group (P <0.05), but the TP values are all within a normal physiological range, and other indexes have no obvious difference compared with the control group. The measured values of all indexes of each administration group in the recovery period are not obviously different from those of a control group. The organs of each group were observed in general without any abnormality.

Example 7: the plant additive of the pig feed provided by the invention can eliminate immunosuppression

Selecting a pig farm frequently suffering from epidemic dermatitis nephrosis type circovirus disease as a main experimental site, respectively selecting 200 heads of piglets, small and medium pigs and large and medium pigs, dividing the piglets into an experimental group and a control group, and feeding the piglets and the control group respectively, wherein the experimental group is fed by 4g of piglets, 7g of small and medium pigs and 10g of medium and large pigs per day, and the specific formula is provided according to the specific formula given in example 1; the control group was fed with normal feed for an experimental period of 30 days.

After 30 days, compared with a control group, the experimental group has the advantages of obviously stimulating appetite, ruddy skin, bright fur, sleep preference, soft excrement and obviously reduced odor. At this time, the swine herd was inoculated with the dermatitis nephrosis circovirus vaccine, and the inoculation condition of the vaccine was observed.

After 60 days, none of the experimental groups was infected with dermatitis nephrotic type circovirus, while the control group was infected with 16 cases. The experimental conclusion that the plant additive of the pig feed can obviously solve the common problem of immunosuppression of the swinery, enhance the immunologic function of the swinery, improve the disease resistance of the organism and enable the swinery to be in a healthy state, thereby realizing the enhancement of the immune effect of the vaccine.

Example 8: the plant additive of the pig feed can prevent diseases of piglets

1. The plant additive of the pig feed is used for preventing blue-ear disease of piglets and promoting weight gain

Selecting a pig farm with frequent occurrence of blue-ear disease, selecting 1000 piglets with uniform weight, and dividing the piglets into a control group and an experimental group, wherein the experimental group is fed with the plant additive of the pig feed, the control group is fed normally, the experimental period is 60 days, and the experimental results are shown in the following table:

2. the plant additive of the pig feed is used for preventing the circovirus disease of weaned pigs

The experimental conditions are the same as those of experiment 1, and the experimental conclusion is that the piglets in the experimental group have no circovirus disease, and the piglets in the control group have 6 cases. Wherein, compared with a control group, the daily gain of the experimental pig after being fed by the feed is improved by 17 percent, and the feed conversion rate is averagely improved by 15.2 percent.

3. The plant additive of the pig feed is used for preventing weaned piglets from suffering from swine fever

The experimental conditions are the same as those of experiment 1, the experimental conclusion is that the piglets in the experimental group have no swine fever, the control group has 46 cases, the weight of each piglet in the experimental group is increased by 35g more than that in the control group every day, and the protection rate is 100%.

Example 9: the plant additive of the pig feed provided by the invention is used for treating pig diseases

Specific examples are as follows:

380 atypical swine fever pigs appear in a certain large pig farm, and the affected pig farm is fed according to the following pig weight (G):

g is less than or equal to 15kg, and 4G is used per day;

g is more than 15 and less than or equal to 50kg, and 7G is used per day;

g is more than or equal to 50kg, and 10G is used daily.

After the pig feed is continuously fed for two weeks, 290 pigs have improved body conditions, and after the pig feed is continuously fed for 1 month, 70 pigs have improved body conditions, and the cure rate of the plant additive of the pig feed is 94.7%.

While embodiments of the invention have been shown and described, it will be understood by those of ordinary skill in the art that: various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the invention, the scope of which is defined by the claims and their equivalents.

Claims

1. The plant additive for the pig feed is characterized by being prepared from the following raw materials in parts by weight:

12 parts of honeysuckle, 12 parts of houttuynia cordata, 15 parts of rhizoma anemarrhenae, 15 parts of red peony root, 15 parts of cortex lycii radicis, 20 parts of astragalus membranaceus, 15 parts of bighead atractylodes rhizome, 20 parts of codonopsis pilosula, 15 parts of white paeony root, 15 parts of angelica sinensis, 15 parts of polygonum multiflorum, 15 parts of rhizoma cyperi, 10 parts of orange peel, 12 parts of fructus aurantii, 10 parts of platycodon grandiflorum and 15 parts of liquorice, 30 parts of gypsum with the water content not more than 8 percent and 391.5 parts of sodium humate.

2. The plant additive for pig feed according to claim 1, wherein the plant additive for pig feed is powder or granule.

3. The method for preparing a plant additive for pig feed according to claim 1 or 2, comprising the steps of:

(5) micronizing gypsum, and sieving with 80-120 mesh sieve;

4. The method for preparing the pig feed plant additive according to claim 3, wherein the time for premixing the Chinese medicinal powder in each group in the step (4) is 5-15 minutes.

5. The method for preparing the plant additive for pig feed according to claim 3 or 4, wherein the step (6) of preparing the sodium humate is to pulverize peat, lignite or weathered coal, and then to react with sodium hydroxide solution sufficiently to obtain supernatant, and then to concentrate and dry the supernatant to obtain the finished product, or to refine the finished product through granulation or other processes, wherein the soluble humic acid is not less than 55%, and the water content is not more than 12%.

6. Use of the plant additive of pig feed according to claim 1 or 2 for the preparation of a medicament for the prevention and treatment of porcine reproductive and respiratory syndrome, hog cholera, and porcine circovirus disease.

7. Use of a plant additive of a pig feed according to claim 1 or 2 for the preparation of a medicament for the elimination of swine herd immunosuppression.