CN105639098A - Green feed additive for livestock and preparation method thereof - Google Patents

Green feed additive for livestock and preparation method thereof Download PDF

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Publication number
CN105639098A
CN105639098A CN201510974107.0A CN201510974107A CN105639098A CN 105639098 A CN105639098 A CN 105639098A CN 201510974107 A CN201510974107 A CN 201510974107A CN 105639098 A CN105639098 A CN 105639098A
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parts
livestock
feed additive
extract
green feed
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汪安国
刘文利
王尚明
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Shandong Xundakang Biological Science & Technology Co Ltd
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Shandong Xundakang Biological Science & Technology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9068Zingiber, e.g. garden ginger
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/288Taraxacum (dandelion)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/34Campanulaceae (Bellflower family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • A61K36/355Lonicera (honeysuckle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/46Eucommiaceae (Eucommia family), e.g. hardy rubber tree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/534Mentha (mint)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/82Theaceae (Tea family), e.g. camellia
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/886Aloeaceae (Aloe family), e.g. aloe vera
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus

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Abstract

The invention relates to a green feed additive for livestock. The additive is prepared by mixing the following components by weight: 15-45 parts of a ginger extract, 10-50 parts of an Radix Astragali extract, 15-45 parts of dandelion, 15-35 parts of saccharicterpenin, 15-35 parts of eucommia, 20-40 parts of mint, 15-35 parts of honeysuckle, 15-35 parts of Platycodon grandiflorum, 10-40 parts of fermented soya bean, 15-35 parts of fructus arctii, 15-35 parts of aloe and 15 -35 parts of licorice. The invention has the following beneficial effects: reasonable prescription, simple preparation, no toxic side effect, no pollution, no drug residue and no drug resistance of the composition, ultrafine pulverization, and high bioavailability. Applications prove that the additive has special effects on the enhancement of immunity and poultry antiviral effect of livestock.

Description

Livestock and poultry green feed additive and its preparation method
Technical field
The present invention relates to livestock and poultry green feed additive and its preparation method, belong to field of animal feed, in particular to a kind of livestock and poultry green feed additive and its preparation method.
Background technology
Immunity of livestock is low, easy infection disease particularly virus disease be common disease, the frequently-occurring disease of livestock and poultry, this disease all can occur throughout the year, is one of main disease of harm livestock and poultry breeding industry.
It is main to add antimicrobial drug, VITAMIN, trace element, antiviral drug etc. that doctor trained in Western medicine prevents and treats this disease, and effect is not very desirable; And the traditional Chinese medical science thinks that the treatment of this disease should adopt invigorating the spleen and replenishing QI, clearing heat and detoxicating principle.
This disease almost spreads all over all livestock and poultry cultivation countries of the world, is widely distributed. At present, treat this disease the most frequently used be Chinese medicine and Western medicine, Chinese medicine is owing to its prescription is unreasonable or just simple pulverizes, and particle diameter is excessive, and drug release is relatively slow, causes its bioavailability lower, and clinical effectiveness is not fine; And antimicrobial drug, antiviral drug are owing to its toxic side effect is strong, easily produce the problem such as resistance and drug residue in Western medicine, on clinical, forbid application.
Therefore research and develop a kind of livestock and poultry with having no side effect, drug residue free, the special efficacy green feed additive produced that has no drug resistance be one of this field scientific research technician new problem anxious to be resolved.
Summary of the invention
It is an object of the invention to overcome above-mentioned weak point, it is provided that a kind of reasonable recipe, preparation are simple, micronizing, bioavailability height, successful, have no side effect, have no drug resistance and the livestock and poultry green feed additive of drug residue and its preparation method.
Implementation of the present invention is as follows for achieving the above object: a kind of livestock and poultry green feed additive, by following component by weight mixed preparing and become: Rhizoma Zingiberis Recens extract 15-45 part, Radix Astragali extract 10-50 part, taraxacum 15-45 part, saccharicter-penin 15-35 part, bark of eucommia 15-35 part, peppermint 20-40 part, Japanese Honeysuckle 15-35 part, balloonflower root 15-35 part, fermented soya bean 10-40 part, Great Burdock Achene 15-35 part, aloe 15-35 part, Radix Glycyrrhizae 15-35 part.
Described various component optimum ratio amount is: Rhizoma Zingiberis Recens extract 30 parts, Radix Astragali extract 30 parts, taraxacum 30 parts, saccharicter-penin 25 parts, the bark of eucommia 25 parts, peppermint 30 parts, Japanese Honeysuckle 25 parts, balloonflower root 25 parts, 25 parts, fermented soya bean, Great Burdock Achene 25 parts, aloe 25 parts, 25 parts, Radix Glycyrrhizae.
A preparation method for livestock and poultry green feed additive, carries out as follows:
(1) 700 order sieves will be crossed after the various composition in prescription respectively micronizing;
(2) take Rhizoma Zingiberis Recens extract 15-45 part, Radix Astragali extract 10-50 part, taraxacum 15-45 part, saccharicter-penin 15-35 part, bark of eucommia 15-35 part, peppermint 20-40 part by weight, mix 5-10 minute to evenly;
(3) take Japanese Honeysuckle 15-35 part, balloonflower root 15-35 part, fermented soya bean 10-40 part, Great Burdock Achene 15-35 part, aloe 15-35 part, Radix Glycyrrhizae 15-35 part by weight, mix 5-10 minute to evenly;
(4) merge the composition that above-mentioned (2), (3) step are obtained, continue mixing 10-15 minute to even.
The medicinal property of each component is as follows:
Ginger: pungent, tepor, returns spleen, lung, stomach warp, having the function of loose cold, the warming middle-JIAO to arrest vomiting of inducing sweat, preventing phlegm from forming and stopping coughing; Cure mainly catch cold, gastrofrigid vomiting, cold productive cough cough.
The Radix Astragali: sweet, warm, returns spleen, lung channel, has the function of invigorating QI to consolidate the body surface resistance, expelling pus and toxin by strengthening QI, expelling pus and promoting granulation, diuresis; Cure mainly lung spleen-deficiency, body abnormal sweating goes out, sinking of QI of middle-JIAO, deficiency of vital energy oedema, sore carbuncle difficulty is burst, burst for a long time do not hold back, the deficiency of blood etc.
Taraxacum: bitter, sweet, cold, returns liver, stomach warp, has function clearing heat and detoxicating, dispersing swelling and dissipating binds, inducing diuresis for treating stranguria syndrome; Cure mainly sore poison, acute mastitis, lung carbuncle, hot eyes, pharyngalgia, jaundice due to damp-heat, hot pouring etc.
Saccharicter-penin: the natural bioactivity substance being made up of carbohydrate, glycoside and organic acid. It is the mixture of triterpene saponin and the carbohydrate extracted from Camellia plant seed grouts, it is a kind of brown color, ashless fine shape crystallization. Saccharicter-penin not only can effectively improve intact animal body's immunity and improve ill immunologic function of livestock and birds, and adjustment nerve immunity, enhancing antiviral functions are had unusual effect. Also there is anti-stress, antimutagenic and resisting pathogenic microbes effect. Saccharicter-penin has obvious scavenging free radicals and anti-oxidant function. Also have and obviously regulate cAMP/cGMP system function, promote protein synthesis and digestive enzyme activity.
The bark of eucommia: sweet, warm, returns liver, kidney channel, has invigorating the liver and kidney, strengthening the bones and muscles, antiabortive function; Cure mainly that lumbago due to renal deficiency, waist are unable, rheumatic arthralgia, threatened abortion etc.
Peppermint: pungent, cool, returns liver, lung channel, has dispelling wind, heat radiation, sweating, opens strongly fragrant function; Cure mainly affection of exogenous wind-heat, swelling and pain in the throat, hot eyes, tripe is swollen, place food does not disappear.
Japanese Honeysuckle: sweet, cold, returns lung, stomach, the heart channel of Hang-Shaoyin, has function clearing heat and detoxicating, heat radiation dispelling wind; Cure mainly warm disease heating, common cold due to wind-heat, cough due to lung-heat, swelling and pain in the throat, toxic-heat and blood stasis, breast swell and pain, too fat to move sore poison etc.
Balloonflower root: bitter, pungent, flat, returns lung channel, have a surname lung, eliminate the phlegm, diuresis, apocenosis function; Cure mainly coughing with a lot of sputum, swelling and pain in the throat, lung carbuncle, sore not burst.
Fermented soya bean: flat, salty, attach to the lung and stomach meridians, have and the function of stomach, the fever and chills that detoxify, go; Cure mainly common cold caused by wind-cold, heating of being afraid of cold, fever and chills headache, nasal obstruction sneeze, stomachache vomiting and diarrhoea etc.
Great Burdock Achene: bitter, acrid, cold, attaches to the lung and stomach meridians, and has the function of dispelling wind and heat pathogens, a surname's lung promoting eruption, resolving toxin and disinhibiting the throat; Cure mainly affection of exogenous wind-heat, cough and asthma, swelling and pain in the throat, carbuncle sore tumefacting virus etc.
Aloe: bitter, cold, returns liver, spleen, stomach, small intestine warp, has the function of the cool liver of heat-clearing, the logical intestines of strong spleen; Cure mainly dampness-heat of the liver, maldigestion, stool is obstructed, dyspepsia tripe is swollen.
Radix Glycyrrhizae: sweet, flat, returns lung, the heart, the spleen channel, have invigorate the spleen and benefit qi, expelling phlegm for arresting cough and middle emergency, removing toxic substances, coordinating the actions of various ingredients in a prescription, cushion toxicity, strong function;Cure mainly weakness of the spleen and the stomach, cough breathe heavily, poisoning etc.
All herbal medicine compatible combination above, for affecting the low various factors of immunity of livestock, play the effect treated both principal and secondary aspect of disease.
The invention has the beneficial effects as follows: reasonable recipe, preparation is simple, and substep mixing is more even; Chinese medicine composition is pollution-free, have no side effect, no drug residue, have no drug resistance, and cost is low, draws materials wide, and micronizing, bioavailability height, curative effect is very remarkable. Application attestation, has special efficacy to raising immunity of livestock, enhancing antiviral effect, and makes its product meat reach nuisanceless requirement, meet the export standard of product, effectively ensure that people's is healthy.
Embodiment
Below in conjunction with better embodiment, to describing in detail as follows according to embodiment provided by the invention:
Embodiment 1
A kind of livestock and poultry green feed additive and its preparation method: carry out as follows: (every part by 10g)
(1) 700 order sieves will be crossed after the various composition in prescription respectively micronizing;
(2) take Rhizoma Zingiberis Recens extract 150 parts, Radix Astragali extract 100 parts, taraxacum 150 parts, saccharicter-penin 150 parts, the bark of eucommia 150 parts, peppermint 200 parts by weight, mix 5-10 minute to evenly;
(3) take Japanese Honeysuckle 150 parts, balloonflower root 150 parts, 100 parts, fermented soya bean, Great Burdock Achene 150 parts, aloe 150 parts, 150 parts, Radix Glycyrrhizae by weight, mix 5-10 minute to evenly;
(4) merge the composition that above-mentioned (2), (3) step are obtained, continue mixing 10-15 minute to even.
Embodiment 2
A kind of livestock and poultry green feed additive and its preparation method: carry out as follows: (every part by 10g)
(1) 700 order sieves will be crossed after the various composition in prescription respectively micronizing;
(2) take Rhizoma Zingiberis Recens extract 300 parts, Radix Astragali extract 300 parts, taraxacum 300 parts, saccharicter-penin 250 parts, the bark of eucommia 250 parts, peppermint 300 parts by weight, mix 5-10 minute to evenly;
(3) take Japanese Honeysuckle 250 parts, balloonflower root 250 parts, 250 parts, fermented soya bean, Great Burdock Achene 250 parts, aloe 250 parts, 250 parts, Radix Glycyrrhizae by weight, mix 5-10 minute to evenly;
(4) merge the composition that above-mentioned (2), (3) step are obtained, continue mixing 10-15 minute to even.
Embodiment 3
A kind of livestock and poultry green feed additive and its preparation method: carry out as follows: (every part by 10g)
(1) 700 order sieves will be crossed after the various composition in prescription respectively micronizing;
(2) take Rhizoma Zingiberis Recens extract 450 parts, Radix Astragali extract 500 parts, taraxacum 450 parts, saccharicter-penin 350 parts, the bark of eucommia 350 parts, peppermint 400 parts by weight, mix 5-10 minute to evenly;
(3) take Japanese Honeysuckle 350 parts, balloonflower root 350 parts, 400 parts, fermented soya bean, Great Burdock Achene 350 parts, aloe 350 parts, 350 parts, Radix Glycyrrhizae by weight, mix 5-10 minute to evenly;
(4) merge the composition that above-mentioned (2), (3) step are obtained, continue mixing 10-15 minute to even.
Clinical trial (one):
In the virus disease of domestic animal, representational porcine influenza is tested. Clinical experiment animal selects 70-80 age day, body weight at 40kg-45kg, and the ill pig into porcine influenza is made a definite diagnosis in laboratory. The isolation of ill pig being raised separately, complete feed of feeding, and be divided into 3 groups at random, often organize 30,3 groups of feeding environments are completely identical, and experiment carries out 7 days altogether; Blank group is left intact, and drug control group " qingwen baidu powder " (referring to " People's Republic of China's veterinary drug allusion quotation " 2000 editions two the 418th page) by specification uses treatment;Chinese medicine composition group of the present invention can by product of the present invention (composition obtained by the embodiment of the present invention 2) the ill pig of feeding etc., day dose be: by the every 100g of the present invention, spice 200kg feeds, every day 2-3 time, is used in conjunction 3-5 day; Reached the object of disease therapy by gastrointestinal absorption after oral. Method of calculation: mortality ratio=dead animal number/experimental animal number �� 100%, curative ratio=healing number of animals/experimental animal number �� 100%. Following table 1 is the result at the end of experiment.
Efficacy assessment standard:
Healing: spirit is normal, drinking-water of searching for food is normal, and breathing is normal, ight soil is normal, and bouncing, laboratory does not detect swine influenza virus etc.
At the end of have symptom: clinical symptom is not improved and is even increased the weight of.
Table 1 is the situation contrast of the present invention and other pharmacological agent porcine influenza:
Numbering Group Mortality ratio % Curative ratio % At the end of have symptom rate %
�� Blank group 33.3 0 66.7
�� Qingwen baidu powder group 13.3 67.7 20
�� Present composition group 6.7 80 13.3
This clinical test results through statistical study, present composition group with antipyretic and detoxicated loose group in curative ratio compared with difference extremely significantly (P < 0.01).
Clinical trial (two):
In the virus disease of poultry, representational chicken infectious bronchitis is tested. Clinical experiment animal selects age on the 20th, body weight at 0.8kg-0.9kg, and the ill broiler chicken into chicken infectious bronchitis is made a definite diagnosis in laboratory. The isolation of ill chicken being raised separately, complete feed of feeding, and be divided into 3 groups at random, often organize 100,3 groups of feeding environments are completely identical, and experimental period carries out 7 days altogether; Blank group is left intact, and drug control group institute's control drug " qingwen baidu powder " (referring to " People's Republic of China's veterinary drug allusion quotation " 2000 editions two the 418th page) uses treatment by its specification sheets; Chinese medicine composition group of the present invention by product of the present invention (composition obtained by the embodiment of the present invention 2) the ill poultry of feeding etc., day dose be: feed or the 400kg that drinks water by the every 100g spice 220kg of the present invention, every day 2-3 time, be used in conjunction 3-5 day; Reached the object of disease therapy by gastrointestinal absorption after oral. Method of calculation: mortality ratio=dead animal number/experimental animal number �� 100%, curative ratio=healing number of animals/experimental animal number �� 100%. Following table 2 is the result at the end of experiment.
Efficacy assessment standard:
Curing: spirit is normal, drinking-water of searching for food is normal, and ight soil is normal, breathes normal etc. Cuing open the inspection histoorgan such as trachea-bronchial epithelial cell, larynx normal, Experimental immunization fluoroscopic examination has no pathogenic micro-organism avian infectious bronchitis virus etc.
At the end of have symptom: clinical symptom is not improved and is even increased the weight of.
Table 2 is the Field information feelings of the present invention and other pharmacological agent chicken infectious bronchitis
Condition contrasts:
Numbering Group Mortality ratio % Curative ratio % At the end of have symptom rate %
�� Blank group 11 8 81
�� Qingwen baidu powder group 7 78 15
�� Chinese medicine composition group of the present invention 5 89 6
This clinical effectiveness is through statistical study, and present composition group is difference extremely remarkable (P < 0.01) compared with qingwen baidu powder group is in curative ratio.
Clinical trial (three):
Clinical experiment animal selects chicken 300 age on the 20th. Experimental chicken isolation being raised separately, complete feed of feeding, and be divided into 3 groups at random, often organize 100,3 groups of feeding environments are completely identical, and experimental period carries out 7 days altogether; 1 group is blank group, is left intact; 2 groups is drug control group, uses treatment with institute's control drug " Fuzheng Jiedu powder " (referring to " People's Republic of China's veterinary drug allusion quotation " 2000 editions two the 375th page) by its specification sheets;3 groups is present composition group, by product of the present invention (composition obtained by the embodiment of the present invention 2) feeding experimental chicken, day dose be: every 100 grams of present composition spices 700 kilograms are fed, every day 1 time; Reached the object improving immunizing power by gastrointestinal absorption after oral.
Test index: bone-marrow-derived lymphocyte EAC rosette rate %=B lymphocyte EAC number positive/total cellular score �� 100%, T lymphocyte ANAE positive rate %=T lymphocyte ANAE number positive/total cellular score �� 100%.
These parameters is the important indicator of mark immunologic function of livestock and birds height.
Following table is the result at the end of experiment.
Table 3 is on the impact of chicken B lymphocyte EAC rosette rate %
Through statistical study, the bone-marrow-derived lymphocyte EAC garland rate of formation pole of of the present invention group is significantly higher than Fuzheng Jiedu powder control group and blank group (P < 0.01), illustrating and improving in bone-marrow-derived lymphocyte EAC garland rate of formation, present composition group effect is remarkable.
Table 4 is on the impact of chicken T lymphocyte ANAE rosette rate %
Through statistical study, T lymphocyte ANAE garland rate of formation pole is significantly higher than Fuzheng Jiedu powder control group and blank group (P < 0.01) by present composition group, illustrating and improving in lymphocyte ANAE garland rate of formation, present composition group effect is remarkable.
Safety testing (one):
Choose healthy broiler chicken 60 age on the 20th, according to the made composition recommended dose of the embodiment of the present invention 25 times of spices or drinking-water 5 days, during medication, healthy broiler chicken is without any bad or abnormal behaviour performance, drinking-water of searching for food is normal, and it is not remarkable that body weight increase compares difference with blank group (i.e. health not administration group).
Safety testing (two):
Choose health pig 10 age on the 70th, feed 10 days according to 5 times of spices of the made composition recommended dose of the embodiment of the present invention 2, during medication, experiment pig is without any bad or abnormal behaviour performance, drinking-water of searching for food is normal, and it is not remarkable that body weight increase compares difference with blank group (i.e. health not administration group).
The above-mentioned detailed description this livestock and poultry green feed additive and its preparation method carried out with reference to embodiment; it it is explanation property instead of limited; some embodiments can be listed according to institute's limited range; therefore in the change not departed under present general inventive concept and amendment, should belong within protection scope of the present invention.

Claims (3)

1. a livestock and poultry green feed additive, is characterized in that: by following component by weight mixed preparing and become: Rhizoma Zingiberis Recens extract 15-45 part, Radix Astragali extract 10-50 part, taraxacum 15-45 part, saccharicter-penin 15-35 part, bark of eucommia 15-35 part, peppermint 20-40 part, Japanese Honeysuckle 15-35 part, balloonflower root 15-35 part, fermented soya bean 10-40 part, Great Burdock Achene 15-35 part, aloe 15-35 part, Radix Glycyrrhizae 15-35 part.
2. livestock and poultry green feed additive according to claim 1, is characterized in that: described various component optimum ratio amount is: Rhizoma Zingiberis Recens extract 30 parts, Radix Astragali extract 30 parts, taraxacum 30 parts, saccharicter-penin 25 parts, the bark of eucommia 25 parts, peppermint 30 parts, Japanese Honeysuckle 25 parts, balloonflower root 25 parts, 25 parts, fermented soya bean, Great Burdock Achene 25 parts, aloe 25 parts, 25 parts, Radix Glycyrrhizae.
3. a preparation method for livestock and poultry green feed additive according to claim 1 and 2, is characterized in that carrying out as follows:
(1) 700 order sieves will be crossed after the various composition in prescription respectively micronizing;
(2) take Rhizoma Zingiberis Recens extract 15-45 part, Radix Astragali extract 10-50 part, taraxacum 15-45 part, saccharicter-penin 15-35 part, bark of eucommia 15-35 part, peppermint 20-40 part by weight, mix 5-10 minute to evenly;
(3) take Japanese Honeysuckle 15-35 part, balloonflower root 15-35 part, fermented soya bean 10-40 part, Great Burdock Achene 15-35 part, aloe 15-35 part, Radix Glycyrrhizae 15-35 part by weight, mix 5-10 minute to evenly;
(4) merge the composition that above-mentioned (2), (3) step are obtained, continue mixing 10-15 minute to even.
CN201510974107.0A 2015-12-22 2015-12-22 Green feed additive for livestock and preparation method thereof Pending CN105639098A (en)

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CN106387435A (en) * 2016-10-20 2017-02-15 中粮饲料有限公司 Feed additive, and application thereof, as well as feed
CN107279562A (en) * 2017-07-06 2017-10-24 合肥皖高特种家禽养殖科技有限公司 A kind of saccharicter-penin promotes the feed of young goose growth
CN109497287A (en) * 2019-01-03 2019-03-22 临沂大学 A kind of feed addictive can promote growth of animal
CN111053153A (en) * 2019-12-12 2020-04-24 河南鑫牧生物科技有限公司 Fermented feed additive for relieving livestock and poultry influenza symptoms and preparation method thereof
CN112868929A (en) * 2021-01-13 2021-06-01 江西正邦动物保健品有限公司 Pig additive containing saccharicterpenin and preparation method and application thereof

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CN102727770A (en) * 2012-06-20 2012-10-17 青岛绿曼生物工程有限公司 Pure traditional Chinese medicine composition used for treating swine influenza, and preparation method thereof
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CN102671025A (en) * 2012-05-24 2012-09-19 山东新希望六和集团有限公司 Chinese herbal feed additive for preventing and treating avian influenza
CN102727770A (en) * 2012-06-20 2012-10-17 青岛绿曼生物工程有限公司 Pure traditional Chinese medicine composition used for treating swine influenza, and preparation method thereof
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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106387435A (en) * 2016-10-20 2017-02-15 中粮饲料有限公司 Feed additive, and application thereof, as well as feed
CN107279562A (en) * 2017-07-06 2017-10-24 合肥皖高特种家禽养殖科技有限公司 A kind of saccharicter-penin promotes the feed of young goose growth
CN109497287A (en) * 2019-01-03 2019-03-22 临沂大学 A kind of feed addictive can promote growth of animal
CN111053153A (en) * 2019-12-12 2020-04-24 河南鑫牧生物科技有限公司 Fermented feed additive for relieving livestock and poultry influenza symptoms and preparation method thereof
CN112868929A (en) * 2021-01-13 2021-06-01 江西正邦动物保健品有限公司 Pig additive containing saccharicterpenin and preparation method and application thereof

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