CN102083461B - 有效的偶联物和亲水性连接体 - Google Patents

有效的偶联物和亲水性连接体 Download PDF

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Publication number
CN102083461B
CN102083461B CN200980125295.2A CN200980125295A CN102083461B CN 102083461 B CN102083461 B CN 102083461B CN 200980125295 A CN200980125295 A CN 200980125295A CN 102083461 B CN102083461 B CN 102083461B
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cell
antibody
conjugate
binding agent
cancer
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Chinese (zh)
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CN102083461A (zh
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R·辛格
Y·科夫通
S·D·威廉
R·V·J·查里
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Immunogen Inc
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Immunogen Inc
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    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
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