ZA201007806B - Potent conjugates and hydrophilic linkers - Google Patents

Potent conjugates and hydrophilic linkers

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Publication number
ZA201007806B
ZA201007806B ZA2010/07806A ZA201007806A ZA201007806B ZA 201007806 B ZA201007806 B ZA 201007806B ZA 2010/07806 A ZA2010/07806 A ZA 2010/07806A ZA 201007806 A ZA201007806 A ZA 201007806A ZA 201007806 B ZA201007806 B ZA 201007806B
Authority
ZA
South Africa
Prior art keywords
hydrophilic linkers
conjugates
potent
potent conjugates
linkers
Prior art date
Application number
ZA2010/07806A
Other languages
English (en)
Inventor
Rajeeva Singh
Yelena Kovtun
Sharon D Wilhelm
Ravi V J Chari
Original Assignee
Immunogen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immunogen Inc filed Critical Immunogen Inc
Publication of ZA201007806B publication Critical patent/ZA201007806B/en

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    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
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