CN101896204B - 用于治疗紫癜的组合物及方法 - Google Patents

用于治疗紫癜的组合物及方法 Download PDF

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Publication number
CN101896204B
CN101896204B CN200880116406.9A CN200880116406A CN101896204B CN 101896204 B CN101896204 B CN 101896204B CN 200880116406 A CN200880116406 A CN 200880116406A CN 101896204 B CN101896204 B CN 101896204B
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CN
China
Prior art keywords
adrenergic receptor
receptor agonist
alpha
agents
purpura
Prior art date
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Expired - Fee Related
Application number
CN200880116406.9A
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English (en)
Chinese (zh)
Other versions
CN101896204A (zh
Inventor
S·D·尚勒
A·翁都
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Aclaris Therapeutics Inc
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Allergan Inc
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Publication of CN101896204A publication Critical patent/CN101896204A/zh
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Expired - Fee Related legal-status Critical Current
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4174—Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
CN200880116406.9A 2007-11-16 2008-11-17 用于治疗紫癜的组合物及方法 Expired - Fee Related CN101896204B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US98856407P 2007-11-16 2007-11-16
US60/988,564 2007-11-16
PCT/US2008/083774 WO2009065116A1 (en) 2007-11-16 2008-11-17 Compositions and methods for treating purpura

Publications (2)

Publication Number Publication Date
CN101896204A CN101896204A (zh) 2010-11-24
CN101896204B true CN101896204B (zh) 2015-05-20

Family

ID=40639204

Family Applications (1)

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CN200880116406.9A Expired - Fee Related CN101896204B (zh) 2007-11-16 2008-11-17 用于治疗紫癜的组合物及方法

Country Status (19)

Country Link
US (4) US8114898B2 (enExample)
EP (3) EP2818184B1 (enExample)
JP (2) JP5670196B2 (enExample)
KR (1) KR101577471B1 (enExample)
CN (1) CN101896204B (enExample)
AU (1) AU2008322411C1 (enExample)
BR (1) BRPI0819075A2 (enExample)
CA (1) CA2703109C (enExample)
DK (1) DK2818184T3 (enExample)
ES (1) ES2709120T3 (enExample)
HR (1) HRP20190214T1 (enExample)
HU (1) HUE042931T2 (enExample)
IL (1) IL205704A (enExample)
MX (1) MX2010005331A (enExample)
PL (1) PL2818184T3 (enExample)
PT (1) PT2818184T (enExample)
SI (1) SI2818184T1 (enExample)
TR (1) TR201901431T4 (enExample)
WO (1) WO2009065116A1 (enExample)

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TWI709417B (zh) 2013-10-07 2020-11-11 美商帝國製藥美國股份有限公司 使用右美托咪啶經皮組成物用於治療注意力不足過動症、焦慮及失眠的方法及組成物
CN105764496B (zh) 2013-10-07 2020-09-25 帝国制药美国公司 用于经皮递送非镇静量的右旋美托咪啶的方法和组合物
TWI704933B (zh) 2013-10-07 2020-09-21 美商帝國製藥美國股份有限公司 右美托咪啶經皮輸送裝置及使用其之方法
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AU2008322411B2 (en) 2014-04-03
SI2818184T1 (sl) 2019-03-29
US8673953B2 (en) 2014-03-18
JP5670196B2 (ja) 2015-02-18
EP2207424A1 (en) 2010-07-21
US9265761B2 (en) 2016-02-23
KR20100098633A (ko) 2010-09-08
US20150018358A1 (en) 2015-01-15
CN101896204A (zh) 2010-11-24
TR201901431T4 (tr) 2019-02-21
AU2008322411C1 (en) 2015-03-12
PT2818184T (pt) 2019-01-28
IL205704A (en) 2015-06-30
HRP20190214T1 (hr) 2019-03-22

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