CN100558243C - 提取、纯化和酶促修饰用作降低血胆固醇剂的大豆7S球蛋白α′亚基的方法 - Google Patents

提取、纯化和酶促修饰用作降低血胆固醇剂的大豆7S球蛋白α′亚基的方法 Download PDF

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CN100558243C
CN100558243C CNB038028050A CN03802805A CN100558243C CN 100558243 C CN100558243 C CN 100558243C CN B038028050 A CNB038028050 A CN B038028050A CN 03802805 A CN03802805 A CN 03802805A CN 100558243 C CN100558243 C CN 100558243C
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conglycinin
polypeptide fragment
soybean
affinity chromatography
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CN1622760A (zh
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M·杜兰蒂
P·莫拉佐尼
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/168—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
    • A23J1/00—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
    • A23J1/00—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites
    • A23J1/14—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites from leguminous or other vegetable seeds; from press-cake or oil-bearing seeds
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
    • A23J3/00—Working-up of proteins for foodstuffs
    • A23J3/14—Vegetable proteins
    • A23J3/16—Vegetable proteins from soybean
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/185—Vegetable proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/06—Ethanol, i.e. non-beverage
    • C—CHEMISTRY; METALLURGY
    • C13—SUGAR INDUSTRY
    • C13K—SACCHARIDES OBTAINED FROM NATURAL SOURCES OR BY HYDROLYSIS OF NATURALLY OCCURRING DISACCHARIDES, OLIGOSACCHARIDES OR POLYSACCHARIDES
    • C13K1/00—Glucose; Glucose-containing syrups
    • C13K1/06—Glucose; Glucose-containing syrups obtained by saccharification of starch or raw materials containing starch
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Nutrition Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Botany (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Mycology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Emergency Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
CNB038028050A 2002-01-29 2003-01-27 提取、纯化和酶促修饰用作降低血胆固醇剂的大豆7S球蛋白α′亚基的方法 Expired - Fee Related CN100558243C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITMI2002A000147 2002-01-29
IT2002MI000147A ITMI20020147A1 (it) 2002-01-29 2002-01-29 Estrazione purificazione e modificazione di polipeptidi da seme di soia

Publications (2)

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CN1622760A CN1622760A (zh) 2005-06-01
CN100558243C true CN100558243C (zh) 2009-11-11

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CNB038028050A Expired - Fee Related CN100558243C (zh) 2002-01-29 2003-01-27 提取、纯化和酶促修饰用作降低血胆固醇剂的大豆7S球蛋白α′亚基的方法

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US (3) US7465467B2 (enExample)
EP (1) EP1469741B1 (enExample)
JP (1) JP4522706B2 (enExample)
KR (1) KR100991641B1 (enExample)
CN (1) CN100558243C (enExample)
AT (1) ATE341943T1 (enExample)
AU (1) AU2003208346B8 (enExample)
CA (1) CA2474106C (enExample)
CY (1) CY1107514T1 (enExample)
DE (1) DE60308994T2 (enExample)
DK (1) DK1469741T3 (enExample)
ES (1) ES2274208T3 (enExample)
IL (1) IL163225A (enExample)
IT (1) ITMI20020147A1 (enExample)
NO (1) NO327156B1 (enExample)
PL (1) PL209342B1 (enExample)
PT (1) PT1469741E (enExample)
RU (1) RU2300898C2 (enExample)
SG (1) SG152048A1 (enExample)
WO (1) WO2003063608A1 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6171640B1 (en) * 1997-04-04 2001-01-09 Monsanto Company High beta-conglycinin products and their use
EP1561384B1 (en) * 2002-11-12 2007-10-10 Fuji Oil Company, Ltd. Fractionated soybean protein and process for producing the same
JP4687463B2 (ja) * 2003-12-11 2011-05-25 不二製油株式会社 改良大豆７ｓたん白及びその製造法
JP5382840B2 (ja) * 2005-08-23 2014-01-08 特定非営利活動法人プライメイト・アゴラ サルモデルで薬効が確認された骨粗鬆症の予防又は治療剤
EP2384124B1 (en) * 2008-12-31 2015-09-16 Solae, Llc Protein hydrolysate compositions
EP2264054A1 (en) * 2009-06-17 2010-12-22 Indena S.p.A. Cloning, yeast expression, purification and biological activity of a truncated form of the soybean 7S globulin alfa ' subunit involved in Hep G2 cell cholesterol homeostasis
SI2264055T1 (sl) * 2009-06-17 2014-05-30 Indena S.P.A. Kloniranje, izraĺ˝anje v kvasovki, äśiĺ äśenje in bioloĺ ka aktivnost ekstenzijske regije alfa'podenote sojinega 7s globulina udeleĺ˝ene pri homeostazi holesterola hepg2 celice
CN101904406B (zh) * 2010-07-02 2012-07-25 山西大学 一种葵花籽多肽的制备方法和用途
CN104163767B (zh) * 2014-07-25 2017-01-18 湖北泓肽生物科技有限公司 一种氨基酸和多肽水溶性物质的纯化方法
CN114874301A (zh) * 2022-05-10 2022-08-09 吉林农业大学 不同亚基组成β-伴大豆球蛋白的制备方法及应用

Citations (1)

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CN1326321A (zh) * 1998-10-07 2001-12-12 孟山都技术有限责任公司 高β－伴大豆球蛋白产品及其用途

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US4409248A (en) 1981-08-10 1983-10-11 A. E. Staley Manufacturing Company Heat-gelling and foam-stabilizing enzymatically modified vegetable isolates
JPH06197788A (ja) 1993-01-06 1994-07-19 Fuji Oil Co Ltd 蛋白質の製造法
DE69700759T2 (de) * 1996-03-28 2000-05-31 Fuji Oil Co., Ltd. Verfahren zur Herstellung eines Sojaproteinhydrolysats
ATE347604T1 (de) * 1996-06-14 2006-12-15 Du Pont Suppressi0n spezifischer klassen von soja- sojasamenproteingenen
US6365802B2 (en) * 1998-08-14 2002-04-02 Calgene Llc Methods for increasing stearate content in soybean oil
FR2784029B1 (fr) * 1998-10-05 2001-01-05 Pharmascience Lab Methode de prevention et/ou de traitement cosmetique des vergetures de la peau et utilisation en dermatologie
MXPA01010486A (es) * 1999-04-15 2002-03-27 Calgene Llc Secuencias de acido nucleico para proteinas implicadas en la sintesis de tocoferol.
CA2274414A1 (en) 1999-06-11 2000-12-11 Universite Laval Dietary fish protein for use in restoring normal insulin function insulin-resistant individuals
AUPQ877300A0 (en) 2000-07-13 2000-08-03 Johnson & Johnson Pacific Pty Limited Topical treatment of skin
KR101238752B1 (ko) * 2002-04-18 2013-03-06 몬산토 테크놀로지 엘엘씨 심혈관 질환의 위험성을 감소시키기 위한 오일 바디 결합 단백질 조성물 및 이의 사용 방법
EP1508573B1 (en) * 2003-08-20 2009-10-28 Seikagaku Corporation Stabilizing agent for enzymes
EP1841333A1 (en) * 2005-01-14 2007-10-10 Solae, Llc Soy protein for infant formula

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CN1326321A (zh) * 1998-10-07 2001-12-12 孟山都技术有限责任公司 高β－伴大豆球蛋白产品及其用途

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大豆蛋白中7S和11S蛋白的功能特性研究. 肖凯军等.中国食品工业，第3期. 1996 *

Also Published As

Publication number Publication date
CN1622760A (zh) 2005-06-01
US20080261885A1 (en) 2008-10-23
NO20043186L (no) 2004-07-26
DK1469741T3 (da) 2007-02-19
CA2474106A1 (en) 2003-08-07
US20110118182A1 (en) 2011-05-19
AU2003208346B8 (en) 2008-07-10
PT1469741E (pt) 2007-01-31
IL163225A (en) 2007-06-17
US20050164337A1 (en) 2005-07-28
NO327156B1 (no) 2009-05-04
AU2003208346A2 (en) 2003-09-02
DE60308994T2 (de) 2007-06-14
PL209342B1 (pl) 2011-08-31
DE60308994D1 (de) 2006-11-23
PL370294A1 (en) 2005-05-16
US7901718B2 (en) 2011-03-08
RU2004123201A (ru) 2005-10-27
KR20040077786A (ko) 2004-09-06
ATE341943T1 (de) 2006-11-15
EP1469741A1 (en) 2004-10-27
EP1469741B1 (en) 2006-10-11
RU2300898C2 (ru) 2007-06-20
CA2474106C (en) 2011-11-22
HK1073590A1 (zh) 2005-10-14
WO2003063608A1 (en) 2003-08-07
KR100991641B1 (ko) 2010-11-04
SG152048A1 (en) 2009-05-29
ITMI20020147A1 (it) 2003-07-29
AU2003208346B2 (en) 2008-03-06
JP4522706B2 (ja) 2010-08-11
ES2274208T3 (es) 2007-05-16
JP2005516043A (ja) 2005-06-02
CY1107514T1 (el) 2013-03-13
US8257758B2 (en) 2012-09-04
ITMI20020147A0 (it) 2002-01-29
US7465467B2 (en) 2008-12-16

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