ATE341943T1 - Verfahren zur extraktion, reinigung und enzymatischen veränderung von soja 7s globulin alpha' untereinheit zur verwendung als hypocholesterol-mischer-wirkstoff - Google Patents

Verfahren zur extraktion, reinigung und enzymatischen veränderung von soja 7s globulin alpha' untereinheit zur verwendung als hypocholesterol-mischer-wirkstoff

Info

Publication number
ATE341943T1
ATE341943T1 AT03706387T AT03706387T ATE341943T1 AT E341943 T1 ATE341943 T1 AT E341943T1 AT 03706387 T AT03706387 T AT 03706387T AT 03706387 T AT03706387 T AT 03706387T AT E341943 T1 ATE341943 T1 AT E341943T1
Authority
AT
Austria
Prior art keywords
subunit
soy
extraction
hypocholesterol
purification
Prior art date
Application number
AT03706387T
Other languages
English (en)
Inventor
Marcello Duranti
Paolo Morazzoni
Original Assignee
Indena Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Indena Spa filed Critical Indena Spa
Application granted granted Critical
Publication of ATE341943T1 publication Critical patent/ATE341943T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23JPROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
    • A23J3/00Working-up of proteins for foodstuffs
    • A23J3/14Vegetable proteins
    • A23J3/16Vegetable proteins from soybean
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/168Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23JPROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
    • A23J1/00Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23JPROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
    • A23J1/00Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites
    • A23J1/14Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites from leguminous or other vegetable seeds; from press-cake or oil-bearing seeds
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17Amino acids, peptides or proteins
    • A23L33/185Vegetable proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/02Nutrients, e.g. vitamins, minerals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/02Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/06Ethanol, i.e. non-beverage
    • CCHEMISTRY; METALLURGY
    • C13SUGAR INDUSTRY
    • C13KSACCHARIDES OBTAINED FROM NATURAL SOURCES OR BY HYDROLYSIS OF NATURALLY OCCURRING DISACCHARIDES, OLIGOSACCHARIDES OR POLYSACCHARIDES
    • C13K1/00Glucose; Glucose-containing syrups
    • C13K1/06Glucose; Glucose-containing syrups obtained by saccharification of starch or raw materials containing starch
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02EREDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00Technologies for the production of fuel of non-fossil origin
    • Y02E50/10Biofuels, e.g. bio-diesel

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Nutrition Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Botany (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Emergency Medicine (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Steroid Compounds (AREA)
AT03706387T 2002-01-29 2003-01-27 Verfahren zur extraktion, reinigung und enzymatischen veränderung von soja 7s globulin alpha' untereinheit zur verwendung als hypocholesterol-mischer-wirkstoff ATE341943T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT2002MI000147A ITMI20020147A1 (it) 2002-01-29 2002-01-29 Estrazione purificazione e modificazione di polipeptidi da seme di soia

Publications (1)

Publication Number Publication Date
ATE341943T1 true ATE341943T1 (de) 2006-11-15

Family

ID=11449014

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03706387T ATE341943T1 (de) 2002-01-29 2003-01-27 Verfahren zur extraktion, reinigung und enzymatischen veränderung von soja 7s globulin alpha' untereinheit zur verwendung als hypocholesterol-mischer-wirkstoff

Country Status (21)

Country Link
US (3) US7465467B2 (de)
EP (1) EP1469741B1 (de)
JP (1) JP4522706B2 (de)
KR (1) KR100991641B1 (de)
CN (1) CN100558243C (de)
AT (1) ATE341943T1 (de)
AU (1) AU2003208346B8 (de)
CA (1) CA2474106C (de)
CY (1) CY1107514T1 (de)
DE (1) DE60308994T2 (de)
DK (1) DK1469741T3 (de)
ES (1) ES2274208T3 (de)
HK (1) HK1073590A1 (de)
IL (1) IL163225A (de)
IT (1) ITMI20020147A1 (de)
NO (1) NO327156B1 (de)
PL (1) PL209342B1 (de)
PT (1) PT1469741E (de)
RU (1) RU2300898C2 (de)
SG (1) SG152048A1 (de)
WO (1) WO2003063608A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6171640B1 (en) * 1997-04-04 2001-01-09 Monsanto Company High beta-conglycinin products and their use
AU2003275628B2 (en) * 2002-11-12 2008-04-03 Fuji Oil Company, Limited Fractionated soybean protein and process for producing the same
WO2005055735A1 (ja) * 2003-12-11 2005-06-23 Fuji Oil Company, Limited 改良大豆7sたん白及びその製造法
JP5382840B2 (ja) * 2005-08-23 2014-01-08 特定非営利活動法人プライメイト・アゴラ サルモデルで薬効が確認された骨粗鬆症の予防又は治療剤
US20110250313A1 (en) * 2008-12-31 2011-10-13 Solae, Llc Protein Hydrolysate Compositions
PL2264055T3 (pl) 2009-06-17 2014-09-30 Indena Spa Klonowanie, ekspresja w drożdżach i aktywność biologiczna regionu wydłużenia podjednostki alfa globuliny sojowej 7S zaangażowanej w homeostazę cholesterolu w komórkach HepG2
EP2264054A1 (de) * 2009-06-17 2010-12-22 Indena S.p.A. Klonierung, Hefeexpression, Aufreinigung und biologische Aktivität einer verkürzten Form der Soja-7S-Globulin-alfa-Untereinheit, die an der Hep-G2-Zellen-Cholesterin-Homöostase beteiligt ist
CN101904406B (zh) * 2010-07-02 2012-07-25 山西大学 一种葵花籽多肽的制备方法和用途
CN104163767B (zh) * 2014-07-25 2017-01-18 湖北泓肽生物科技有限公司 一种氨基酸和多肽水溶性物质的纯化方法
CN114874301A (zh) * 2022-05-10 2022-08-09 吉林农业大学 不同亚基组成β-伴大豆球蛋白的制备方法及应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4409248A (en) * 1981-08-10 1983-10-11 A. E. Staley Manufacturing Company Heat-gelling and foam-stabilizing enzymatically modified vegetable isolates
JPH06197788A (ja) * 1993-01-06 1994-07-19 Fuji Oil Co Ltd 蛋白質の製造法
US6022702A (en) * 1996-03-28 2000-02-08 Fuji Oil Company Limited Process for producing a soy protein hydrolysate
JP3928811B2 (ja) * 1996-06-14 2007-06-13 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー 特定のクラスのダイズ種子タンパク質遺伝子の抑制
US6171640B1 (en) * 1997-04-04 2001-01-09 Monsanto Company High beta-conglycinin products and their use
US6365802B2 (en) * 1998-08-14 2002-04-02 Calgene Llc Methods for increasing stearate content in soybean oil
FR2784029B1 (fr) 1998-10-05 2001-01-05 Pharmascience Lab Methode de prevention et/ou de traitement cosmetique des vergetures de la peau et utilisation en dermatologie
AU776316B2 (en) * 1999-04-15 2004-09-02 Monsanto Company Nucleic acid sequences to proteins involved in tocopherol synthesis
CA2274414A1 (en) 1999-06-11 2000-12-11 Universite Laval Dietary fish protein for use in restoring normal insulin function insulin-resistant individuals
AUPQ877300A0 (en) * 2000-07-13 2000-08-03 Johnson & Johnson Pacific Pty Limited Topical treatment of skin
NZ536466A (en) * 2002-04-18 2008-04-30 Monsanto Technology Llc Oil body associated protein compositions and methods of use thereof for reducing the risk of cardiovascular disease
EP1508573B1 (de) * 2003-08-20 2009-10-28 Seikagaku Corporation Stabilisierungsmittel für Enzyme
US20060159826A1 (en) * 2005-01-14 2006-07-20 Wong Theodore M Soy protein for infant formula

Also Published As

Publication number Publication date
KR20040077786A (ko) 2004-09-06
US7901718B2 (en) 2011-03-08
CY1107514T1 (el) 2013-03-13
AU2003208346B2 (en) 2008-03-06
CA2474106C (en) 2011-11-22
AU2003208346B8 (en) 2008-07-10
JP2005516043A (ja) 2005-06-02
SG152048A1 (en) 2009-05-29
EP1469741B1 (de) 2006-10-11
US20110118182A1 (en) 2011-05-19
WO2003063608A1 (en) 2003-08-07
PT1469741E (pt) 2007-01-31
HK1073590A1 (en) 2005-10-14
DE60308994T2 (de) 2007-06-14
DK1469741T3 (da) 2007-02-19
CN1622760A (zh) 2005-06-01
US7465467B2 (en) 2008-12-16
ITMI20020147A0 (it) 2002-01-29
NO327156B1 (no) 2009-05-04
CN100558243C (zh) 2009-11-11
JP4522706B2 (ja) 2010-08-11
CA2474106A1 (en) 2003-08-07
RU2004123201A (ru) 2005-10-27
ES2274208T3 (es) 2007-05-16
RU2300898C2 (ru) 2007-06-20
EP1469741A1 (de) 2004-10-27
PL209342B1 (pl) 2011-08-31
NO20043186L (no) 2004-07-26
IL163225A (en) 2007-06-17
US20050164337A1 (en) 2005-07-28
US8257758B2 (en) 2012-09-04
US20080261885A1 (en) 2008-10-23
KR100991641B1 (ko) 2010-11-04
ITMI20020147A1 (it) 2003-07-29
PL370294A1 (en) 2005-05-16
AU2003208346A2 (en) 2003-09-02
DE60308994D1 (de) 2006-11-23

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