CH678815A5 - - Google Patents

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Publication number
CH678815A5
CH678815A5 CH936/88A CH93688A CH678815A5 CH 678815 A5 CH678815 A5 CH 678815A5 CH 936/88 A CH936/88 A CH 936/88A CH 93688 A CH93688 A CH 93688A CH 678815 A5 CH678815 A5 CH 678815A5
Authority
CH
Switzerland
Prior art keywords
ida
mice
antibody
tumor
cells
Prior art date
Application number
CH936/88A
Other languages
German (de)
English (en)
Inventor
Ian Farquhar Campbell Mckenzie
Geoffrey Allan Pietersz
Mark John Smyth
Original Assignee
Erba Carlo Spa
Univ Melbourne
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Carlo Spa, Univ Melbourne filed Critical Erba Carlo Spa
Publication of CH678815A5 publication Critical patent/CH678815A5/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/44—Antibodies bound to carriers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
    • A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
    • A61K47/6807—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug or compound being a sugar, nucleoside, nucleotide, nucleic acid, e.g. RNA antisense
    • A61K47/6809—Antibiotics, e.g. antitumor antibiotics anthracyclins, adriamycin, doxorubicin or daunomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CH936/88A 1987-03-11 1988-03-11 CH678815A5 ( )

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AUPI080387 1987-03-11
AUPI295587 1987-07-07

Publications (1)

Publication Number Publication Date
CH678815A5 true CH678815A5 ( ) 1991-11-15

Family

ID=25643244

Family Applications (1)

Application Number Title Priority Date Filing Date
CH936/88A CH678815A5 ( ) 1987-03-11 1988-03-11

Country Status (29)

Country Link
US (1) US5798097A ( )
JP (1) JP2736255B2 ( )
KR (1) KR0130906B1 ( )
CN (1) CN1045621C ( )
AT (1) AT395375B ( )
AU (1) AU622105B2 ( )
BE (1) BE1001051A4 ( )
CA (1) CA1329156C ( )
CH (1) CH678815A5 ( )
CZ (1) CZ281193B6 ( )
DE (1) DE3808166C2 ( )
DK (1) DK173792B1 ( )
ES (1) ES2006109A6 ( )
FI (1) FI98706C ( )
FR (1) FR2612074B1 ( )
GB (1) GB2203154B ( )
GR (1) GR1000059B ( )
HU (1) HU205266B ( )
IE (1) IE64781B1 ( )
IL (1) IL85688A0 ( )
IT (1) IT8819746A0 ( )
MY (1) MY103231A ( )
NL (1) NL8800610A ( )
NO (1) NO178954C ( )
NZ (1) NZ223834A ( )
PT (1) PT86960B ( )
RU (1) RU2106147C1 ( )
SE (1) SE503402C2 ( )
YU (1) YU46858B ( )

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6824777B1 (en) * 1992-10-09 2004-11-30 Licentia Ltd. Flt4 (VEGFR-3) as a target for tumor imaging and anti-tumor therapy
DK1119371T3 (da) * 1998-10-09 2011-03-07 Vegenics Ltd Flt4 (VEGFR-3) som et mål for tumorbilleddannelse og antitumorterapi
EP1343531A2 (en) * 2000-12-21 2003-09-17 McGILL UNIVERSITY Conjugates of antibodies and anticancer drugs
JP4669984B2 (ja) 2001-01-19 2011-04-13 ベジェニクス リミテッド 腫瘍画像化のターゲットとしてのＦ１ｔ４（ＶＥＧＦＲ−３）および抗腫瘍療法
CA2522700A1 (en) * 2003-04-18 2004-11-04 Cytovia, Inc. Methods of treating diseases responsive to induction of apoptosis and screening assays
GB0511266D0 (en) * 2005-06-02 2005-07-13 Trust Chemical compounds
US20080108138A1 (en) * 2006-06-13 2008-05-08 Vermette Patrick Bioactive compositions and their use in cell patterning
CN110251668A (zh) 2010-11-30 2019-09-20 霍夫曼-拉罗奇有限公司 低亲和力血脑屏障受体抗体及其用途
NZ710658A (en) 2013-02-18 2019-12-20 Vegenics Pty Ltd Ligand binding molecules and uses thereof

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT343811B (de) * 1975-01-22 1978-06-26 Farmaceutici Italia Verfahren zur herstellung von neuen optisch aktiven anthracyclinonen
AT346838B (de) * 1975-01-22 1978-11-27 Farmaceutici Italia Verfahren zur herstellung von neuen optisch aktiven anthracyclinonen
GB1500421A (en) * 1975-01-22 1978-02-08 Farmaceutici Italia Optically active anthracyclinones
AT343812B (de) * 1975-01-22 1978-06-26 Farmaceutici Italia Verfahren zur herstellung von neuen optisch aktiven daunosaminylderivaten von anthracyclinonen
GB1511680A (en) 1975-11-18 1978-05-24 Farmaceutici Italia Daunosaminyl anthracyclinones
GB1541436A (en) * 1976-02-02 1979-02-28 Searle & Co Immunological materials
US4867973A (en) * 1984-08-31 1989-09-19 Cytogen Corporation Antibody-therapeutic agent conjugates
US5162512A (en) * 1982-03-09 1992-11-10 Cytogen Corporation Amine derivatives of anthracycline antibodies
US4950738A (en) * 1984-09-13 1990-08-21 Cytogen Corporation Amine derivatives of anthracycline antibiotics
JPS59186924A (ja) * 1983-04-08 1984-10-23 Kureha Chem Ind Co Ltd ヒト免疫グロブリン結合抗腫瘍剤
US4545985A (en) 1984-01-26 1985-10-08 The United States Of America As Represented By The Secretary, Dept. Of Health And Human Services Pseudomonas exotoxin conjugate immunotoxins
GB8413464D0 (en) * 1984-05-25 1984-07-04 Erba Farmitalia Anthracycline-anionic polymer conjugates
JPS61155334A (ja) * 1984-12-28 1986-07-15 Teijin Ltd 殺細胞性修飾免疫グロブリン及びその製造方法
FR2584293B1 (fr) * 1985-07-04 1989-03-17 Ire Celltarg Sa Anticorps utiles comme agents de pilotage et conjugues les incorporant

Also Published As

Publication number Publication date
FI881158A0 (fi) 1988-03-11
GB8805865D0 (en) 1988-04-13
NL8800610A (nl) 1988-10-03
DK131588A (da) 1988-09-12
FI98706B (fi) 1997-04-30
FR2612074A1 (fr) 1988-09-16
NO881105D0 (no) 1988-03-11
GR1000059B (el) 1990-06-27
CZ161288A3 (en) 1996-07-17
IL85688A0 (en) 1988-08-31
YU48288A (en) 1989-08-31
DK131588D0 (da) 1988-03-11
NL195078C ( ) 2003-07-30
PT86960A (pt) 1988-04-01
YU46858B (sh) 1994-06-24
SE8800886D0 (sv) 1988-03-11
AU1288188A (en) 1988-09-15
FI98706C (fi) 1997-08-11
KR0130906B1 (ko) 1998-04-23
PT86960B (pt) 1992-06-30
DK173792B1 (da) 2001-11-05
JPS63301832A (ja) 1988-12-08
IT8819746A0 (it) 1988-03-11
CZ281193B6 (cs) 1996-07-17
DE3808166C2 (de) 1997-08-28
IE64781B1 (en) 1995-09-06
KR880010775A (ko) 1988-10-24
CA1329156C (en) 1994-05-03
ES2006109A6 (es) 1989-04-01
GB2203154A (en) 1988-10-12
RU2106147C1 (ru) 1998-03-10
BE1001051A4 (fr) 1989-06-20
CN1045621C (zh) 1999-10-13
FR2612074B1 (fr) 1991-06-21
HU205266B (en) 1992-04-28
AU622105B2 (en) 1992-04-02
GB2203154B (en) 1991-06-26
ATA67488A (de) 1992-05-15
SE503402C2 (sv) 1996-06-10
CN88101810A (zh) 1988-11-09
DE3808166A1 (de) 1988-09-22
FI881158A (fi) 1988-09-12
GR880100148A (en) 1989-01-31
US5798097A (en) 1998-08-25
SE8800886L (sv) 1989-09-12
AT395375B (de) 1992-12-10
JP2736255B2 (ja) 1998-04-02
NO881105L (no) 1988-09-12
IE880701L (en) 1988-09-11
NO178954C (no) 1996-07-10
NO178954B (no) 1996-04-01
MY103231A (en) 1993-05-29
NZ223834A (en) 1990-05-28
HUT46547A (en) 1988-11-28

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Legal Events

Date Code Title Description
PFA Name/firm changed

Owner name: THE UNIVERSITY OF MELBOURNE;FARMITALIA CARLO ERBA

PL Patent ceased