GB1541436A - Immunological materials - Google Patents

Immunological materials

Info

Publication number
GB1541436A
GB1541436A GB50070/76A GB5007076A GB1541436A GB 1541436 A GB1541436 A GB 1541436A GB 50070/76 A GB50070/76 A GB 50070/76A GB 5007076 A GB5007076 A GB 5007076A GB 1541436 A GB1541436 A GB 1541436A
Authority
GB
United Kingdom
Prior art keywords
immunological materials
immunological
materials
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB50070/76A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GD Searle LLC
Original Assignee
GD Searle LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GD Searle LLC filed Critical GD Searle LLC
Priority to GB50070/76A priority Critical patent/GB1541436A/en
Publication of GB1541436A publication Critical patent/GB1541436A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/44—Antibodies bound to carriers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/645—Polycationic or polyanionic oligopeptides, polypeptides or polyamino acids, e.g. polylysine, polyarginine, polyglutamic acid or peptide TAT
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
    • A61K47/6883—Polymer-drug antibody conjugates, e.g. mitomycin-dextran-Ab; DNA-polylysine-antibody complex or conjugate used for therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
GB50070/76A 1976-02-02 1976-02-02 Immunological materials Expired GB1541436A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB50070/76A GB1541436A (en) 1976-02-02 1976-02-02 Immunological materials

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB50070/76A GB1541436A (en) 1976-02-02 1976-02-02 Immunological materials

Publications (1)

Publication Number Publication Date
GB1541436A true GB1541436A (en) 1979-02-28

Family

ID=10454535

Family Applications (1)

Application Number Title Priority Date Filing Date
GB50070/76A Expired GB1541436A (en) 1976-02-02 1976-02-02 Immunological materials

Country Status (1)

Country Link
GB (1) GB1541436A (en)

Cited By (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0037388A2 (en) * 1980-03-31 1981-10-07 Institut International De Pathologie Cellulaire Et Moleculaire Pharmaceutical forms, their preparation and compositions containing the same
EP0040506A2 (en) * 1980-05-21 1981-11-25 Teijin Limited Reactive polymer and process for the preparation thereof
US4401592A (en) 1978-12-29 1983-08-30 Kureha Kagaku Kogyo Kabushiki Kaisha Pharmaceutical composition having antitumor activity
GB2116979A (en) * 1982-02-25 1983-10-05 Ward Page Faulk Conjugates of proteins with anti- tumour agents
EP0111388A2 (en) * 1982-11-10 1984-06-20 Inco Alloys International, Inc. Therapeutic compounds of platinum and palladium and their preparation
EP0112720A2 (en) * 1982-12-24 1984-07-04 Teijin Limited Conjugate having cytotoxicity and process for the preparation thereof
EP0114685A2 (en) * 1983-01-21 1984-08-01 The Green Cross Corporation Fibronectin complexes
EP0115171A2 (en) * 1982-12-24 1984-08-08 Teijin Limited Conjugate having cytotoxicity and process for the preparation thereof
EP0190464A2 (en) * 1984-12-31 1986-08-13 Yeda Research And Development Company Limited Novel anti-cancer drugs
FR2583983A1 (en) * 1985-06-07 1987-01-02 Centre Nat Rech Scient NEW WATER-SOLUBLE MACROMOLECULAR PRODUCTS, THEIR PREPARATION AND THEIR USE AS MEDICAMENTS, IN PARTICULAR ANTI-TUMOR AND PEST CONTROL
GB2203154A (en) * 1987-03-11 1988-10-12 Erba Carlo Spa Immunoglobulin conjugates
EP0315456A2 (en) * 1987-11-05 1989-05-10 Hybritech Incorporated Polysaccharide-modified immunoglobulins having reduced immunogenic potential or improved pharmacokinetics
EP0328147A2 (en) * 1988-02-11 1989-08-16 Bristol-Myers Squibb Company Anthracycline immunoconjugates having a novel linker and methods for their production
EP0383170A2 (en) * 1989-02-11 1990-08-22 Hoechst Aktiengesellschaft Methotrexate linked to polymers, process for their preparation, and use
FR2646608A1 (en) * 1989-05-04 1990-11-09 Wisconsin Alumni Res Found COMPLEXES FOR LOCATING AND TREATING TUMORS, AND TEST KIT INCLUDING ONE OF SUCH COMPLEXES
EP0510132A1 (en) * 1990-09-28 1992-10-28 Neorx Corp Polymeric carriers for release of covalently linked agents.
US5230883A (en) * 1989-05-04 1993-07-27 Wisconsin Alumni Research Foundation Method for localization and treatment of tumors using polylysine complexes
WO1995005200A1 (en) * 1993-08-18 1995-02-23 European Community Drug delivery agents incorporating mitomycin
EP0648503A1 (en) * 1993-09-22 1995-04-19 BEHRINGWERKE Aktiengesellschaft Pro-prodrugs, their production and use
WO1997021452A2 (en) * 1995-12-14 1997-06-19 Advanced Magnetics, Inc. Macromolecular prodrugs of nucleotide analogs
WO1997040854A2 (en) * 1996-05-01 1997-11-06 Antivirals Inc. Polypeptide conjugates for transporting substances across cell membranes
EP0595133A3 (en) * 1992-10-27 1998-11-04 BEHRINGWERKE Aktiengesellschaft Prodrugs, their preparation and use as medicaments
US6030941A (en) * 1996-05-01 2000-02-29 Avi Biopharma, Inc. Polymer composition for delivering substances in living organisms

Cited By (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4401592A (en) 1978-12-29 1983-08-30 Kureha Kagaku Kogyo Kabushiki Kaisha Pharmaceutical composition having antitumor activity
EP0037388A2 (en) * 1980-03-31 1981-10-07 Institut International De Pathologie Cellulaire Et Moleculaire Pharmaceutical forms, their preparation and compositions containing the same
EP0037388A3 (en) * 1980-03-31 1982-06-02 Institut International De Pathologie Cellulaire Et Moleculaire Pharmaceutical forms, their preparation and compositions containing the same
EP0040506A2 (en) * 1980-05-21 1981-11-25 Teijin Limited Reactive polymer and process for the preparation thereof
EP0040506A3 (en) * 1980-05-21 1982-11-10 Teijin Limited Reactive polymer and process for the preparation thereof
GB2116979A (en) * 1982-02-25 1983-10-05 Ward Page Faulk Conjugates of proteins with anti- tumour agents
EP0134320A1 (en) * 1982-02-25 1985-03-20 FAULK, Ward Page Conjugates of proteins with anti-tumour agents
WO1985000812A1 (en) * 1982-02-25 1985-02-28 Eyles, Christopher, Thomas Conjugates of proteins with anti-tumour agents
EP0111388A2 (en) * 1982-11-10 1984-06-20 Inco Alloys International, Inc. Therapeutic compounds of platinum and palladium and their preparation
EP0111388A3 (en) * 1982-11-10 1984-09-05 Inco Research & Development Center, Inc. Therapeutic compounds of platinum and palladium and their preparation
EP0115171A2 (en) * 1982-12-24 1984-08-08 Teijin Limited Conjugate having cytotoxicity and process for the preparation thereof
EP0112720A2 (en) * 1982-12-24 1984-07-04 Teijin Limited Conjugate having cytotoxicity and process for the preparation thereof
EP0112720A3 (en) * 1982-12-24 1986-10-29 Teijin Limited Conjugate having cytotoxicity and process for the preparation thereof
EP0115171A3 (en) * 1982-12-24 1986-10-29 Teijin Limited Conjugate having cytotoxicity and process for the preparation thereof
EP0114685B1 (en) * 1983-01-21 1990-04-04 The Green Cross Corporation Fibronectin complexes
EP0114685A2 (en) * 1983-01-21 1984-08-01 The Green Cross Corporation Fibronectin complexes
EP0190464A3 (en) * 1984-12-31 1987-02-04 Yeda Research And Development Company Limited Novel anti-cancer drugs
EP0190464A2 (en) * 1984-12-31 1986-08-13 Yeda Research And Development Company Limited Novel anti-cancer drugs
FR2583983A1 (en) * 1985-06-07 1987-01-02 Centre Nat Rech Scient NEW WATER-SOLUBLE MACROMOLECULAR PRODUCTS, THEIR PREPARATION AND THEIR USE AS MEDICAMENTS, IN PARTICULAR ANTI-TUMOR AND PEST CONTROL
US4753984A (en) * 1985-06-07 1988-06-28 Centre National De La Recherche Scientifique (Cnrs) Water soluble macromolecular prodrugs, their preparation and their use as antitumor and antiparasite medicines
EP0208576A1 (en) * 1985-06-07 1987-01-14 Centre National De La Recherche Scientifique (Cnrs) Macromolecular and hydrosuluble prodrugs, their preparation and their use as medicaments, especially antitumorous and antiparasitic ones
US5798097A (en) * 1987-03-11 1998-08-25 Pharmacia & Upjohn S.P.A. Immunogobulin conjugates
GB2203154A (en) * 1987-03-11 1988-10-12 Erba Carlo Spa Immunoglobulin conjugates
GB2203154B (en) * 1987-03-11 1991-06-26 Erba Carlo Spa Immunoglobulin conjugates
EP0315456A3 (en) * 1987-11-05 1990-03-28 Hybritech Incorporated Polysaccharide-modified immunoglobulins having reduced immunogenic potential or improved pharmacokinetics
EP0315456A2 (en) * 1987-11-05 1989-05-10 Hybritech Incorporated Polysaccharide-modified immunoglobulins having reduced immunogenic potential or improved pharmacokinetics
EP0328147A2 (en) * 1988-02-11 1989-08-16 Bristol-Myers Squibb Company Anthracycline immunoconjugates having a novel linker and methods for their production
EP0328147A3 (en) * 1988-02-11 1991-11-13 Bristol-Myers Squibb Company Anthracycline immunoconjugates having a novel linker and methods for their production
EP0383170A2 (en) * 1989-02-11 1990-08-22 Hoechst Aktiengesellschaft Methotrexate linked to polymers, process for their preparation, and use
EP0383170A3 (en) * 1989-02-11 1990-12-27 Hoechst Aktiengesellschaft Methotrexate linked to polymers, process for their preparation, and use
EP0471790A4 (en) * 1989-05-04 1992-07-08 Wisconsin Alumni Research Foundation Method for localization and treatment of tumors and complexes therefor
FR2646608A1 (en) * 1989-05-04 1990-11-09 Wisconsin Alumni Res Found COMPLEXES FOR LOCATING AND TREATING TUMORS, AND TEST KIT INCLUDING ONE OF SUCH COMPLEXES
US5230883A (en) * 1989-05-04 1993-07-27 Wisconsin Alumni Research Foundation Method for localization and treatment of tumors using polylysine complexes
EP0471790A1 (en) * 1989-05-04 1992-02-26 Wisconsin Alumni Research Foundation Method for localization and treatment of tumors and complexes therefor
EP0510132A1 (en) * 1990-09-28 1992-10-28 Neorx Corp Polymeric carriers for release of covalently linked agents.
EP0510132A4 (en) * 1990-09-28 1993-02-24 Neorx Corporation Polymeric carriers for release of covalently linked agents
US5549883A (en) * 1990-09-28 1996-08-27 Neorx Corporation Chemically defined polymeric carriers for release of covalently linked agents
US6146658A (en) * 1992-10-27 2000-11-14 Hoechst Aktiengesellschaft Prodrugs, their preparation and use as pharmaceuticals
EP0595133A3 (en) * 1992-10-27 1998-11-04 BEHRINGWERKE Aktiengesellschaft Prodrugs, their preparation and use as medicaments
WO1995005200A1 (en) * 1993-08-18 1995-02-23 European Community Drug delivery agents incorporating mitomycin
AU681180B2 (en) * 1993-09-22 1997-08-21 Behringwerke Aktiengesellschaft Pro-prodrugs, their production and use
EP0648503A1 (en) * 1993-09-22 1995-04-19 BEHRINGWERKE Aktiengesellschaft Pro-prodrugs, their production and use
WO1997021452A3 (en) * 1995-12-14 1997-10-09 Advanced Magnetics Inc Macromolecular prodrugs of nucleotide analogs
WO1997021452A2 (en) * 1995-12-14 1997-06-19 Advanced Magnetics, Inc. Macromolecular prodrugs of nucleotide analogs
US5981507A (en) * 1995-12-14 1999-11-09 Advanced Magnetics, Inc. Polymeric carriers linked to nucleotide analogues via a phosphoramide bond
WO1997040854A2 (en) * 1996-05-01 1997-11-06 Antivirals Inc. Polypeptide conjugates for transporting substances across cell membranes
WO1997040854A3 (en) * 1996-05-01 1998-03-12 Antivirals Inc Polypeptide conjugates for transporting substances across cell membranes
US6030941A (en) * 1996-05-01 2000-02-29 Avi Biopharma, Inc. Polymer composition for delivering substances in living organisms
AU729643B2 (en) * 1996-05-01 2001-02-08 Antivirals Inc. Polypeptide conjugates for transporting substances across cell membranes

Similar Documents

Publication Publication Date Title
GB1541435A (en) Immunological materials
AU517514B2 (en) 3-de-0-methylfortimicins
AU2542577A (en) 4-amino-4-arylcyclohexanones
AU2384277A (en) Triazolo-pyrimidines
GB1541436A (en) Immunological materials
AU3191677A (en) Cyclopentan-1-amine
AU2726877A (en) Benzofuranyl-benzimidazoles
JPS5358500A (en) Novel zeolitefuu1
AU3298878A (en) Separating materials
AU507260B2 (en) N-2-imidazolidinylidene-benzeneamine
AU2451277A (en) Isothiazolopyridines
AU2714177A (en) Phenoxy-hydroxypropylamines
PH13880A (en) Novel aryltrifluoroethylamines
AU1309176A (en) Fire-barriers
BG23251A1 (en) Stabilograph
ZA777586B (en) Novel o-propyloximes
BG28564A4 (en) - 3- cyclohexen- 1- ona
JPS539791A (en) Novel 77alphaa oxyiminoacycephalosporin
JPS52121455A (en) Toothhbruching things
AU2893177A (en) Perhydroindolinols
AU508067B2 (en) Electroradiography
ZA777423B (en) Novel d-homosteroids
AU2493077A (en) 2-amino-substituted-isothioureido bewzenes
JPS52142722A (en) Indicating materials
AU3192177A (en) 2-methoxybenzamides

Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee