CH655116A5 - Mitomycin-analoge verbindungen und sie enthaltende pharmazeutische praeparate. - Google Patents

Mitomycin-analoge verbindungen und sie enthaltende pharmazeutische praeparate. Download PDF

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Publication number
CH655116A5
CH655116A5 CH2580/82A CH258082A CH655116A5 CH 655116 A5 CH655116 A5 CH 655116A5 CH 2580/82 A CH2580/82 A CH 2580/82A CH 258082 A CH258082 A CH 258082A CH 655116 A5 CH655116 A5 CH 655116A5
Authority
CH
Switzerland
Prior art keywords
methoxy
hexahydro
hydroxymethyl
azirino
indole
Prior art date
Application number
CH2580/82A
Other languages
German (de)
English (en)
Inventor
William A Remers
Original Assignee
University Patents Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University Patents Inc filed Critical University Patents Inc
Publication of CH655116A5 publication Critical patent/CH655116A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CH2580/82A 1981-05-15 1982-04-27 Mitomycin-analoge verbindungen und sie enthaltende pharmazeutische praeparate. CH655116A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US26418781A 1981-05-15 1981-05-15

Publications (1)

Publication Number Publication Date
CH655116A5 true CH655116A5 (de) 1986-03-27

Family

ID=23004963

Family Applications (1)

Application Number Title Priority Date Filing Date
CH2580/82A CH655116A5 (de) 1981-05-15 1982-04-27 Mitomycin-analoge verbindungen und sie enthaltende pharmazeutische praeparate.

Country Status (27)

Country Link
JP (1) JPS57188590A (xx)
KR (1) KR890000935B1 (xx)
AT (1) AT375943B (xx)
AU (1) AU559686B2 (xx)
BE (1) BE893162A (xx)
CA (1) CA1244412A (xx)
CH (1) CH655116A5 (xx)
DE (1) DE3217769A1 (xx)
DK (1) DK161078C (xx)
ES (1) ES8303417A1 (xx)
FI (1) FI78100C (xx)
FR (1) FR2505839B1 (xx)
GB (1) GB2106096B (xx)
GR (1) GR76033B (xx)
HU (1) HU186510B (xx)
IE (1) IE52956B1 (xx)
IL (1) IL64998A0 (xx)
IT (1) IT1156453B (xx)
LU (1) LU84144A1 (xx)
NL (1) NL8200839A (xx)
NO (1) NO158743C (xx)
NZ (1) NZ199617A (xx)
PH (1) PH20358A (xx)
PT (1) PT74895B (xx)
SE (1) SE450895B (xx)
YU (1) YU44819B (xx)
ZA (1) ZA82923B (xx)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA833967B (en) * 1982-06-04 1984-02-29 Bristol Myers Co Amidines
DE3376114D1 (en) * 1982-12-07 1988-05-05 Kyowa Hakko Kogyo Kk Mitomycin analogues
NZ206932A (en) * 1983-02-07 1987-08-31 University Patents Inc Certain 6-(heterocyclyl or amino) mitosanes and pharmaceutical compositions
US4803212A (en) * 1983-04-11 1989-02-07 Bristol-Myers Company Amino disulfides
US4642352A (en) * 1983-12-23 1987-02-10 Bristol-Myers Company Acylamino mitosanes
JPS60255789A (ja) * 1984-06-01 1985-12-17 Kyowa Hakko Kogyo Co Ltd マイトマイシン誘導体，その製造法および抗腫瘍剤
FR2571373A1 (fr) * 1984-10-09 1986-04-11 Bristol Myers Co Procede de preparation de derives n7-substitues de la mitomycine c
DE3674043D1 (de) * 1985-04-10 1990-10-18 Kyowa Hakko Kogyo Kk Pharmakologisch aktive mitomycinderivate.
US5023253A (en) * 1987-12-21 1991-06-11 University Patents, Inc. 6-substituted mitomycin analogs
MX356344B (es) * 2011-10-20 2018-05-23 Oryzon Genomics Sa Compuestos de (hetero)arilciclopropilamina como inhibidores de lsd1.

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL129868C (xx) * 1963-06-07
US3420846A (en) * 1964-08-25 1969-01-07 Kyowa Hakko Kogyo Kk 7-substituted mitomycin a
US3332944A (en) * 1964-11-02 1967-07-25 American Cyanamid Co Antibiotic derivatives of mitomycins a, b, c and porfiromycin
JPS5439098A (en) * 1977-08-31 1979-03-24 Kyowa Hakko Kogyo Co Ltd Mitomycin c derivatives
US4268676A (en) * 1979-12-05 1981-05-19 University Patents, Inc. Mitomycin analogs
JPS5686184A (en) * 1979-12-17 1981-07-13 Kyowa Hakko Kogyo Co Ltd Novel mitomycin c derivative

Also Published As

Publication number Publication date
IE820431L (en) 1982-11-15
IT8267321A0 (it) 1982-03-15
FI821241A0 (fi) 1982-04-07
CA1244412A (en) 1988-11-08
AT375943B (de) 1984-09-25
NO158743B (no) 1988-07-18
FI78100B (fi) 1989-02-28
ES511874A0 (es) 1983-02-01
HU186510B (en) 1985-08-28
IT1156453B (it) 1987-02-04
FR2505839B1 (fr) 1985-11-08
IE52956B1 (en) 1988-04-27
KR830009102A (ko) 1983-12-17
DK219182A (da) 1982-11-16
BE893162A (fr) 1982-08-30
FI821241L (fi) 1982-11-16
ZA82923B (en) 1983-01-26
IL64998A0 (en) 1982-04-30
YU97282A (en) 1985-04-30
LU84144A1 (fr) 1982-09-13
YU44819B (en) 1991-02-28
SE8203035L (sv) 1982-11-16
ATA184482A (de) 1984-02-15
SE450895B (sv) 1987-08-10
PT74895B (en) 1984-08-02
GB2106096A (en) 1983-04-07
NO158743C (no) 1988-10-26
FI78100C (fi) 1989-06-12
KR890000935B1 (ko) 1989-04-14
NZ199617A (en) 1985-08-30
DE3217769A1 (de) 1982-12-09
PH20358A (en) 1986-12-04
DK161078C (da) 1991-11-11
NL8200839A (nl) 1982-12-01
JPS57188590A (en) 1982-11-19
GR76033B (xx) 1984-08-03
ES8303417A1 (es) 1983-02-01
AU559686B2 (en) 1987-03-19
NO821598L (no) 1982-11-16
FR2505839A1 (fr) 1982-11-19
AU8268282A (en) 1983-11-17
PT74895A (en) 1982-06-01
DK161078B (da) 1991-05-27
GB2106096B (en) 1985-12-04

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