JPS57188590A - Novel mitomycin derivative - Google Patents

Novel mitomycin derivative

Info

Publication number
JPS57188590A
JPS57188590A JP57065598A JP6559882A JPS57188590A JP S57188590 A JPS57188590 A JP S57188590A JP 57065598 A JP57065598 A JP 57065598A JP 6559882 A JP6559882 A JP 6559882A JP S57188590 A JPS57188590 A JP S57188590A
Authority
JP
Japan
Prior art keywords
mitomycin derivative
novel mitomycin
novel
derivative
mitomycin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP57065598A
Other languages
English (en)
Inventor
Ei Rimaasu Uiriamu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University Patents Inc
Original Assignee
University Patents Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University Patents Inc filed Critical University Patents Inc
Publication of JPS57188590A publication Critical patent/JPS57188590A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
JP57065598A 1981-05-15 1982-04-19 Novel mitomycin derivative Pending JPS57188590A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US26418781A 1981-05-15 1981-05-15

Publications (1)

Publication Number Publication Date
JPS57188590A true JPS57188590A (en) 1982-11-19

Family

ID=23004963

Family Applications (1)

Application Number Title Priority Date Filing Date
JP57065598A Pending JPS57188590A (en) 1981-05-15 1982-04-19 Novel mitomycin derivative

Country Status (27)

Country Link
JP (1) JPS57188590A (ja)
KR (1) KR890000935B1 (ja)
AT (1) AT375943B (ja)
AU (1) AU559686B2 (ja)
BE (1) BE893162A (ja)
CA (1) CA1244412A (ja)
CH (1) CH655116A5 (ja)
DE (1) DE3217769A1 (ja)
DK (1) DK161078C (ja)
ES (1) ES8303417A1 (ja)
FI (1) FI78100C (ja)
FR (1) FR2505839B1 (ja)
GB (1) GB2106096B (ja)
GR (1) GR76033B (ja)
HU (1) HU186510B (ja)
IE (1) IE52956B1 (ja)
IL (1) IL64998A0 (ja)
IT (1) IT1156453B (ja)
LU (1) LU84144A1 (ja)
NL (1) NL8200839A (ja)
NO (1) NO158743C (ja)
NZ (1) NZ199617A (ja)
PH (1) PH20358A (ja)
PT (1) PT74895B (ja)
SE (1) SE450895B (ja)
YU (1) YU44819B (ja)
ZA (1) ZA82923B (ja)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS591486A (ja) * 1982-06-04 1984-01-06 ブリストル―マイヤーズ　スクイブ　カンパニー アミジン類
JPS59152384A (ja) * 1983-02-07 1984-08-31 ユニヴア−シテイ　パテンツ，インコ−ポレイテツド マイトマイシン類似物
US4691024A (en) * 1984-06-01 1987-09-01 Kyowa Hakko Kogyo Kabushiki Kaisha New mitomycin derivatives, preparation thereof and pharmaceutical compositions containing them
US4771068A (en) * 1985-04-10 1988-09-13 Kyowa Hakko Kogyo Kabushiki Kaisha Mitomycin derivatives having anti-tumor and antibacterial utility
KR20140081884A (ko) * 2011-10-20 2014-07-01 오리존 지노믹스 에스.에이. Lsd1 억제제로서 (헤테로)아릴 사이클로프로필아민 화합물

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0116208B1 (en) * 1982-12-07 1988-03-30 Kyowa Hakko Kogyo Co., Ltd. Mitomycin analogues
US4803212A (en) * 1983-04-11 1989-02-07 Bristol-Myers Company Amino disulfides
US4642352A (en) * 1983-12-23 1987-02-10 Bristol-Myers Company Acylamino mitosanes
FR2571373A1 (fr) * 1984-10-09 1986-04-11 Bristol Myers Co Procede de preparation de derives n7-substitues de la mitomycine c
US5023253A (en) * 1987-12-21 1991-06-11 University Patents, Inc. 6-substituted mitomycin analogs

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5439098A (en) * 1977-08-31 1979-03-24 Kyowa Hakko Kogyo Co Ltd Mitomycin c derivatives
JPS5686184A (en) * 1979-12-17 1981-07-13 Kyowa Hakko Kogyo Co Ltd Novel mitomycin c derivative

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL129868C (ja) * 1963-06-07
US3420846A (en) * 1964-08-25 1969-01-07 Kyowa Hakko Kogyo Kk 7-substituted mitomycin a
US3332944A (en) * 1964-11-02 1967-07-25 American Cyanamid Co Antibiotic derivatives of mitomycins a, b, c and porfiromycin
US4268676A (en) * 1979-12-05 1981-05-19 University Patents, Inc. Mitomycin analogs

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5439098A (en) * 1977-08-31 1979-03-24 Kyowa Hakko Kogyo Co Ltd Mitomycin c derivatives
JPS5686184A (en) * 1979-12-17 1981-07-13 Kyowa Hakko Kogyo Co Ltd Novel mitomycin c derivative

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS591486A (ja) * 1982-06-04 1984-01-06 ブリストル―マイヤーズ　スクイブ　カンパニー アミジン類
JPH0472838B2 (ja) * 1982-06-04 1992-11-19 Squibb Bristol Myers Co
JPS59152384A (ja) * 1983-02-07 1984-08-31 ユニヴア−シテイ　パテンツ，インコ−ポレイテツド マイトマイシン類似物
US4691024A (en) * 1984-06-01 1987-09-01 Kyowa Hakko Kogyo Kabushiki Kaisha New mitomycin derivatives, preparation thereof and pharmaceutical compositions containing them
US4771068A (en) * 1985-04-10 1988-09-13 Kyowa Hakko Kogyo Kabushiki Kaisha Mitomycin derivatives having anti-tumor and antibacterial utility
KR20140081884A (ko) * 2011-10-20 2014-07-01 오리존 지노믹스 에스.에이. Lsd1 억제제로서 (헤테로)아릴 사이클로프로필아민 화합물
JP2014532619A (ja) * 2011-10-20 2014-12-08 オリゾン・ジェノミックス・ソシエダッド・アノニマＯｒｙｚｏｎ Ｇｅｎｏｍｉｃｓ Ｓ．Ａ． Ｌｓｄ１阻害剤としての（ヘテロ）アリールシクロプロピルアミン化合物
US9487512B2 (en) 2011-10-20 2016-11-08 Oryzon Genomics S.A. (Hetero)aryl cyclopropylamine compounds as LSD1 inhibitors
JP2017226671A (ja) * 2011-10-20 2017-12-28 オリゾン・ジェノミックス・ソシエダッド・アノニマＯｒｙｚｏｎ Ｇｅｎｏｍｉｃｓ Ｓ．Ａ． Ｌｓｄ１阻害剤としての（ヘテロ）アリールシクロプロピルアミン化合物
US9944601B2 (en) 2011-10-20 2018-04-17 Oryzon Genomics, S.A. (Hetero)aryl cyclopropylamine compounds as LSD1 inhibitors

Also Published As

Publication number Publication date
SE450895B (sv) 1987-08-10
FI78100B (fi) 1989-02-28
YU97282A (en) 1985-04-30
FI821241A0 (fi) 1982-04-07
IT1156453B (it) 1987-02-04
ES511874A0 (es) 1983-02-01
KR830009102A (ko) 1983-12-17
HU186510B (en) 1985-08-28
IT8267321A0 (it) 1982-03-15
NO158743C (no) 1988-10-26
PH20358A (en) 1986-12-04
NO821598L (no) 1982-11-16
DK161078B (da) 1991-05-27
FI821241L (fi) 1982-11-16
PT74895B (en) 1984-08-02
ZA82923B (en) 1983-01-26
BE893162A (fr) 1982-08-30
DE3217769A1 (de) 1982-12-09
LU84144A1 (fr) 1982-09-13
NZ199617A (en) 1985-08-30
FR2505839A1 (fr) 1982-11-19
CH655116A5 (de) 1986-03-27
DK219182A (da) 1982-11-16
FI78100C (fi) 1989-06-12
YU44819B (en) 1991-02-28
PT74895A (en) 1982-06-01
DK161078C (da) 1991-11-11
GR76033B (ja) 1984-08-03
SE8203035L (sv) 1982-11-16
GB2106096A (en) 1983-04-07
IL64998A0 (en) 1982-04-30
NL8200839A (nl) 1982-12-01
FR2505839B1 (fr) 1985-11-08
IE820431L (en) 1982-11-15
NO158743B (no) 1988-07-18
CA1244412A (en) 1988-11-08
AU8268282A (en) 1983-11-17
AT375943B (de) 1984-09-25
GB2106096B (en) 1985-12-04
AU559686B2 (en) 1987-03-19
KR890000935B1 (ko) 1989-04-14
ATA184482A (de) 1984-02-15
ES8303417A1 (es) 1983-02-01
IE52956B1 (en) 1988-04-27

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