CH637159A5 - Preparation of an antibiotic mixture - Google Patents
Preparation of an antibiotic mixture Download PDFInfo
- Publication number
- CH637159A5 CH637159A5 CH627277A CH627277A CH637159A5 CH 637159 A5 CH637159 A5 CH 637159A5 CH 627277 A CH627277 A CH 627277A CH 627277 A CH627277 A CH 627277A CH 637159 A5 CH637159 A5 CH 637159A5
- Authority
- CH
- Switzerland
- Prior art keywords
- antibiotic
- factor
- mixture
- dihydrochloride
- medium
- Prior art date
Links
- 230000003115 biocidal effect Effects 0.000 title claims description 86
- 239000000203 mixture Substances 0.000 title claims description 81
- 238000002360 preparation method Methods 0.000 title claims description 13
- 239000003242 anti bacterial agent Substances 0.000 title description 32
- 108010025808 A35512 antibiotic complex Proteins 0.000 claims description 252
- HGPIFQIEQCQPPE-UHFFFAOYSA-N antibiotic a 35512 Chemical compound C=1C2=CC=C(OC3C(C(O)C(O)C(CO)O3)O)C=1C1=C(O)C=C(O)C=C1C(C(=O)OC)NC(=O)C(C(C1=CC=C(C=C1)OC=1C=C3C=C(C=1OC1C(C(OC4C(C(O)C(O)C(C)O4)O)C(O)C(CO)O1)O)OC1=CC=C(C=C1)C1O)OC4OC(C)C(O)C(C)(N)C4)NC(=O)C2NC(=O)C3NC(=O)C(C(C=2Cl)=C3)NC(=O)C1NC(=O)C(N)C1=CC=CC(O)=C1OC3=CC=2OC1OC(C)C(O)C(O)C1O HGPIFQIEQCQPPE-UHFFFAOYSA-N 0.000 claims description 251
- 102000003712 Complement factor B Human genes 0.000 claims description 132
- 108090000056 Complement factor B Proteins 0.000 claims description 132
- 239000002609 medium Substances 0.000 claims description 60
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims description 34
- 108010053085 Complement Factor H Proteins 0.000 claims description 33
- 102000016550 Complement Factor H Human genes 0.000 claims description 33
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- 239000013642 negative control Substances 0.000 description 1
- 229910052759 nickel Inorganic materials 0.000 description 1
- FEMOMIGRRWSMCU-UHFFFAOYSA-N ninhydrin Chemical compound C1=CC=C2C(=O)C(O)(O)C(=O)C2=C1 FEMOMIGRRWSMCU-UHFFFAOYSA-N 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 239000006916 nutrient agar Substances 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 1
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 description 1
- 150000007524 organic acids Chemical class 0.000 description 1
- 229940094984 other estrogen in atc Drugs 0.000 description 1
- 238000012856 packing Methods 0.000 description 1
- WLJNZVDCPSBLRP-UHFFFAOYSA-N pamoic acid Chemical compound C1=CC=C2C(CC=3C4=CC=CC=C4C=C(C=3O)C(=O)O)=C(O)C(C(O)=O)=CC2=C1 WLJNZVDCPSBLRP-UHFFFAOYSA-N 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 229940074571 peptostreptococcus anaerobius Drugs 0.000 description 1
- 230000001766 physiological effect Effects 0.000 description 1
- 230000035479 physiological effects, processes and functions Effects 0.000 description 1
- OXNIZHLAWKMVMX-UHFFFAOYSA-N picric acid Chemical compound OC1=C([N+]([O-])=O)C=C([N+]([O-])=O)C=C1[N+]([O-])=O OXNIZHLAWKMVMX-UHFFFAOYSA-N 0.000 description 1
- 239000013641 positive control Substances 0.000 description 1
- GNSKLFRGEWLPPA-UHFFFAOYSA-M potassium dihydrogen phosphate Chemical compound [K+].OP(O)([O-])=O GNSKLFRGEWLPPA-UHFFFAOYSA-M 0.000 description 1
- 229910000160 potassium phosphate Inorganic materials 0.000 description 1
- 235000011009 potassium phosphates Nutrition 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 238000000634 powder X-ray diffraction Methods 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 238000003825 pressing Methods 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 229940055019 propionibacterium acne Drugs 0.000 description 1
- 239000012264 purified product Substances 0.000 description 1
- 230000002285 radioactive effect Effects 0.000 description 1
- MUPFEKGTMRGPLJ-ZQSKZDJDSA-N raffinose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO[C@@H]2[C@@H]([C@@H](O)[C@@H](O)[C@@H](CO)O2)O)O1 MUPFEKGTMRGPLJ-ZQSKZDJDSA-N 0.000 description 1
- 239000011541 reaction mixture Substances 0.000 description 1
- 230000035484 reaction time Effects 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011877 solvent mixture Substances 0.000 description 1
- 239000004334 sorbic acid Substances 0.000 description 1
- 235000010199 sorbic acid Nutrition 0.000 description 1
- 229940075582 sorbic acid Drugs 0.000 description 1
- 238000001179 sorption measurement Methods 0.000 description 1
- 239000004455 soybean meal Substances 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 238000010561 standard procedure Methods 0.000 description 1
- 239000008117 stearic acid Substances 0.000 description 1
- 229960004274 stearic acid Drugs 0.000 description 1
- 239000008223 sterile water Substances 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 229940031000 streptococcus pneumoniae Drugs 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000010414 supernatant solution Substances 0.000 description 1
- 239000011975 tartaric acid Substances 0.000 description 1
- 235000002906 tartaric acid Nutrition 0.000 description 1
- 229960001367 tartaric acid Drugs 0.000 description 1
- 238000001757 thermogravimetry curve Methods 0.000 description 1
- 235000015113 tomato pastes and purées Nutrition 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- KHPCPRHQVVSZAH-UHFFFAOYSA-N trans-cinnamyl beta-D-glucopyranoside Natural products OC1C(O)C(O)C(CO)OC1OCC=CC1=CC=CC=C1 KHPCPRHQVVSZAH-UHFFFAOYSA-N 0.000 description 1
- 229950002929 trinitrophenol Drugs 0.000 description 1
- 239000001974 tryptic soy broth Substances 0.000 description 1
- 108010050327 trypticase-soy broth Proteins 0.000 description 1
- OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 description 1
- 238000000825 ultraviolet detection Methods 0.000 description 1
- 238000002255 vaccination Methods 0.000 description 1
- 229960005486 vaccine Drugs 0.000 description 1
- MYPYJXKWCTUITO-LYRMYLQWSA-N vancomycin Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=C2C=C3C=C1OC1=CC=C(C=C1Cl)[C@@H](O)[C@H](C(N[C@@H](CC(N)=O)C(=O)N[C@H]3C(=O)N[C@H]1C(=O)N[C@H](C(N[C@@H](C3=CC(O)=CC(O)=C3C=3C(O)=CC=C1C=3)C(O)=O)=O)[C@H](O)C1=CC=C(C(=C1)Cl)O2)=O)NC(=O)[C@@H](CC(C)C)NC)[C@H]1C[C@](C)(N)[C@H](O)[C@H](C)O1 MYPYJXKWCTUITO-LYRMYLQWSA-N 0.000 description 1
- 229960003165 vancomycin Drugs 0.000 description 1
- MYPYJXKWCTUITO-UHFFFAOYSA-N vancomycin Natural products O1C(C(=C2)Cl)=CC=C2C(O)C(C(NC(C2=CC(O)=CC(O)=C2C=2C(O)=CC=C3C=2)C(O)=O)=O)NC(=O)C3NC(=O)C2NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(CC(C)C)NC)C(O)C(C=C3Cl)=CC=C3OC3=CC2=CC1=C3OC1OC(CO)C(O)C(O)C1OC1CC(C)(N)C(O)C(C)O1 MYPYJXKWCTUITO-UHFFFAOYSA-N 0.000 description 1
- 239000012808 vapor phase Substances 0.000 description 1
- 230000009105 vegetative growth Effects 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07G—COMPOUNDS OF UNKNOWN CONSTITUTION
- C07G11/00—Antibiotics
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/195—Antibiotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Polymers & Plastics (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Zoology (AREA)
- Animal Husbandry (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Food Science & Technology (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Fodder In General (AREA)
- Compounds Of Unknown Constitution (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Feed For Specific Animals (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US68927476A | 1976-05-24 | 1976-05-24 | |
| US05/689,273 US4029769A (en) | 1976-05-24 | 1976-05-24 | Antibiotic A-35512B aglycone |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CH637159A5 true CH637159A5 (en) | 1983-07-15 |
Family
ID=27104372
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH627277A CH637159A5 (en) | 1976-05-24 | 1977-05-20 | Preparation of an antibiotic mixture |
Country Status (24)
| Country | Link |
|---|---|
| JP (1) | JPS532401A (cs) |
| AR (1) | AR212651A1 (cs) |
| AT (1) | AT350717B (cs) |
| AU (1) | AU513827B2 (cs) |
| BG (1) | BG28271A3 (cs) |
| CH (1) | CH637159A5 (cs) |
| CS (1) | CS207457B2 (cs) |
| DD (1) | DD132503A5 (cs) |
| DE (1) | DE2722645A1 (cs) |
| DK (1) | DK225877A (cs) |
| FR (1) | FR2352828A1 (cs) |
| GR (1) | GR66427B (cs) |
| HK (1) | HK27181A (cs) |
| HU (1) | HU179013B (cs) |
| IE (1) | IE45501B1 (cs) |
| KE (1) | KE3132A (cs) |
| MX (1) | MX4232E (cs) |
| MY (1) | MY8200039A (cs) |
| NL (1) | NL7705664A (cs) |
| NZ (1) | NZ184142A (cs) |
| PL (3) | PL108561B1 (cs) |
| PT (1) | PT66567B (cs) |
| SE (1) | SE7705855L (cs) |
| SU (1) | SU833166A3 (cs) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5129884U (cs) * | 1974-08-28 | 1976-03-04 | ||
| GR75473B (cs) * | 1981-04-20 | 1984-07-23 | Lilly Co Eli | |
| GB2137087B (en) * | 1983-03-18 | 1987-02-18 | American Cyanamid Co | Improving milk production |
| GB8608798D0 (en) * | 1986-04-11 | 1986-05-14 | Lepetit Spa | Recovery of glycopeptide antibiotics from aqueous solutions |
| RU2771176C1 (ru) * | 2021-08-31 | 2022-04-28 | Федеральное государственное бюджетное научное учреждение "Федеральный исследовательский центр "Красноярский научный центр Сибирского отделения Российской академии наук" | Способ приготовления биологически активной кормовой добавки для коров |
-
1977
- 1977-05-12 AU AU25110/77A patent/AU513827B2/en not_active Expired
- 1977-05-17 SE SE7705855A patent/SE7705855L/xx not_active Application Discontinuation
- 1977-05-18 NZ NZ184142A patent/NZ184142A/xx unknown
- 1977-05-18 PT PT66567A patent/PT66567B/pt unknown
- 1977-05-18 DE DE19772722645 patent/DE2722645A1/de not_active Withdrawn
- 1977-05-18 FR FR7715272A patent/FR2352828A1/fr active Granted
- 1977-05-18 GR GR53497A patent/GR66427B/el unknown
- 1977-05-20 IE IE1033/77A patent/IE45501B1/en unknown
- 1977-05-20 AR AR267724A patent/AR212651A1/es active
- 1977-05-20 CH CH627277A patent/CH637159A5/de not_active IP Right Cessation
- 1977-05-20 HU HU77EI742A patent/HU179013B/hu unknown
- 1977-05-23 PL PL1977198342A patent/PL108561B1/pl unknown
- 1977-05-23 DD DD7700199066A patent/DD132503A5/xx unknown
- 1977-05-23 JP JP5971177A patent/JPS532401A/ja active Pending
- 1977-05-23 NL NL7705664A patent/NL7705664A/xx not_active Application Discontinuation
- 1977-05-23 PL PL1977216678A patent/PL128225B1/pl unknown
- 1977-05-23 DK DK225877A patent/DK225877A/da not_active Application Discontinuation
- 1977-05-23 CS CS773396A patent/CS207457B2/cs unknown
- 1977-05-23 AT AT366877A patent/AT350717B/de not_active IP Right Cessation
- 1977-05-23 PL PL19384277A patent/PL193842A1/xx unknown
- 1977-05-23 BG BG036390A patent/BG28271A3/xx unknown
- 1977-05-30 MX MX775752U patent/MX4232E/es unknown
-
1978
- 1978-04-27 SU SU782610502A patent/SU833166A3/ru active
-
1981
- 1981-06-02 KE KE3132A patent/KE3132A/xx unknown
- 1981-06-18 HK HK271/81A patent/HK27181A/xx unknown
-
1982
- 1982-12-30 MY MY39/82A patent/MY8200039A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2511077A (en) | 1978-11-16 |
| AR212651A1 (es) | 1978-08-31 |
| SU833166A3 (ru) | 1981-05-23 |
| GR66427B (cs) | 1981-03-20 |
| PT66567A (en) | 1977-06-01 |
| HU179013B (en) | 1982-08-28 |
| JPS532401A (en) | 1978-01-11 |
| DD132503A5 (de) | 1978-10-04 |
| HK27181A (en) | 1981-06-26 |
| NL7705664A (nl) | 1977-11-28 |
| PT66567B (en) | 1978-10-18 |
| PL193842A1 (pl) | 1978-02-27 |
| AT350717B (de) | 1979-06-11 |
| MY8200039A (en) | 1982-12-31 |
| PL128225B1 (en) | 1984-01-31 |
| SE7705855L (sv) | 1977-11-25 |
| NZ184142A (en) | 1979-11-01 |
| AU513827B2 (en) | 1981-01-08 |
| FR2352828B1 (cs) | 1982-10-15 |
| DK225877A (da) | 1977-11-25 |
| IE45501L (en) | 1977-11-24 |
| MX4232E (es) | 1982-02-19 |
| BG28271A3 (en) | 1980-03-25 |
| DE2722645A1 (de) | 1977-12-08 |
| PL108561B1 (en) | 1980-04-30 |
| CS207457B2 (en) | 1981-07-31 |
| ATA366877A (de) | 1978-11-15 |
| KE3132A (en) | 1981-06-19 |
| IE45501B1 (en) | 1982-09-08 |
| FR2352828A1 (fr) | 1977-12-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PL | Patent ceased | ||
| PL | Patent ceased |