CH560180A5 - Pleuromutilin derivs - with antibacterial activity - Google Patents

Pleuromutilin derivs - with antibacterial activity

Info

Publication number
CH560180A5
CH560180A5 CH1445071A CH1445071A CH560180A5 CH 560180 A5 CH560180 A5 CH 560180A5 CH 1445071 A CH1445071 A CH 1445071A CH 1445071 A CH1445071 A CH 1445071A CH 560180 A5 CH560180 A5 CH 560180A5
Authority
CH
Switzerland
Prior art keywords
formula
sulfur
pleuromutilin
compound
deoxy
Prior art date
Application number
CH1445071A
Other languages
German (de)
English (en)
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to BE789629D priority Critical patent/BE789629A/xx
Application filed by Sandoz Ag filed Critical Sandoz Ag
Priority to CH1445071A priority patent/CH560180A5/de
Priority to DK475372AA priority patent/DK139720B/da
Priority to SE7212374A priority patent/SE398348B/xx
Priority to FI2645/72A priority patent/FI58635C/fi
Priority to NO3453/72A priority patent/NO136459C/no
Priority to NLAANVRAGE7213254,A priority patent/NL177403C/xx
Priority to PH13949A priority patent/PH11870A/en
Priority to DE2248237A priority patent/DE2248237C2/de
Priority to GB4525972A priority patent/GB1410505A/en
Priority to CY98772A priority patent/CY987A/xx
Priority to DE2265666A priority patent/DE2265666C2/de
Priority to GB1633875A priority patent/GB1410506A/en
Priority to RO7281506A priority patent/RO67479A/ro
Priority to AT845872A priority patent/AT335054B/de
Priority to CA153,116A priority patent/CA979447A/en
Priority to ES407263A priority patent/ES407263A1/es
Priority to IE1339/72A priority patent/IE37699B1/xx
Priority to IE218872A priority patent/IE37700B1/xx
Priority to PL15805172A priority patent/PL85200B1/pl
Priority to HUSA2407A priority patent/HU168436B/hu
Priority to RO7281505A priority patent/RO67478A/ro
Priority to BG023482A priority patent/BG20773A3/xx
Priority to OA54711A priority patent/OA04192A/xx
Priority to JP9913872A priority patent/JPS577147B2/ja
Priority to IL40494A priority patent/IL40494A/en
Priority to SU1835486A priority patent/SU523632A3/ru
Priority to AU47405/72A priority patent/AU484191B2/en
Priority to BG023481A priority patent/BG21386A3/xx
Priority to IL4726272A priority patent/IL47262A/en
Priority to CS670172A priority patent/CS219306B2/cs
Priority to YU249772A priority patent/YU37125B/xx
Priority to ZA727125A priority patent/ZA727125B/xx
Priority to DD166051A priority patent/DD100706A5/xx
Priority to FR7235340A priority patent/FR2157828B1/fr
Priority to NO4617/73A priority patent/NO136837C/no
Priority to NO4618/73A priority patent/NO137440C/no
Publication of CH560180A5 publication Critical patent/CH560180A5/de
Priority to US05/606,430 priority patent/US4032530A/en
Priority to SE7509456A priority patent/SE424074B/xx
Priority to SE7509457A priority patent/SE419984B/xx
Priority to DK498176A priority patent/DK142700B/da
Priority to DK498076A priority patent/DK140592B/da
Priority to US05/758,133 priority patent/US4107164A/en
Priority to US05/912,497 priority patent/US4208326A/en
Priority to HK25379A priority patent/HK25379A/xx
Priority to US06/098,333 priority patent/US4278674A/en
Priority to FI794061A priority patent/FI60204C/fi
Priority to FI794060A priority patent/FI60198C/fi
Priority to MY7900103A priority patent/MY7900103A/xx
Priority to JP55152399A priority patent/JPS5852994B2/ja
Priority to JP15239880A priority patent/JPS5695163A/ja

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/57—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C323/58—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups with amino groups bound to the carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CH1445071A 1971-10-05 1971-10-05 Pleuromutilin derivs - with antibacterial activity CH560180A5 (en)

Priority Applications (51)

Application Number Priority Date Filing Date Title
BE789629D BE789629A (fr) 1971-10-05 Nouveaux derives de la pleuromutiline, leur preparation et leurapplication en therapeutique
CH1445071A CH560180A5 (en) 1971-10-05 1971-10-05 Pleuromutilin derivs - with antibacterial activity
DK475372AA DK139720B (da) 1971-10-05 1972-09-26 Analogifremgangsmåde til fremstilling af pleuromutiliner.
SE7212374A SE398348B (sv) 1971-10-05 1972-09-26 Forfarande for framstellning av substituerade pleuromutiliner
FI2645/72A FI58635C (fi) 1971-10-05 1972-09-26 Foerfarande foer framstaellning av nya antimikrobiska pleuromutiliner
NO3453/72A NO136459C (no) 1971-10-05 1972-09-27 Analogifremgangsm}te for fremstilling av antimikrobielt virksomme pleuromutiliner.
NLAANVRAGE7213254,A NL177403C (nl) 1971-10-05 1972-09-29 Werkwijze voor het vervaardigen van een farmaceutisch preparaat met antimicrobiele werking op basis van een 14-desoxy-14-acetoxymutilinederivaat en werkwijze voor het bereiden van een verbinding geschikt voor toepassing bij voornoemde werkwijze.
PH13949A PH11870A (en) 1971-10-05 1972-09-29 14-desoxy-14-(substituted acetoxy)mutilins,their pharmaceutical compositions and method inhibiting bacterial infection
DE2248237A DE2248237C2 (de) 1971-10-05 1972-10-02 Pleuromutilin-Derivate, deren Herstellung und pharmazeutische Zubereitung
GB4525972A GB1410505A (en) 1971-10-05 1972-10-02 Pleuromutilins
CY98772A CY987A (en) 1971-10-05 1972-10-02 Pleuromutilin derivative
DE2265666A DE2265666C2 (de) 1971-10-05 1972-10-02 Pleuromutilin-Derivate, deren Herstellung und pharmazeutische Zubereitung
GB1633875A GB1410506A (en) 1971-10-05 1972-10-02 Pleuromutilin derivative
RO7281506A RO67479A (ro) 1971-10-05 1972-10-03 Procedeu pentru prepararea unor pleuromutiline
AT845872A AT335054B (de) 1971-10-05 1972-10-03 Verfahren zur herstellung neuer pleuromutiline
CA153,116A CA979447A (en) 1971-10-05 1972-10-03 Pleuro mutilins
ES407263A ES407263A1 (es) 1971-10-05 1972-10-03 Procedimiento para la obtencion de pleuromutilinas.
IE1339/72A IE37699B1 (en) 1971-10-05 1972-10-03 Novel pleuromutilins
IE218872A IE37700B1 (en) 1971-10-05 1972-10-03 Novel pleuromutilin
PL15805172A PL85200B1 (en) 1971-10-05 1972-10-03 Pleuromutilin derivative [gb1410506a]
HUSA2407A HU168436B (ja) 1971-10-05 1972-10-03
RO7281505A RO67478A (ro) 1971-10-05 1972-10-03 Procedeu pentru prepararea unor pleuromutiline
BG023482A BG20773A3 (bg) 1971-10-05 1972-10-04 Метод за получаване на плевромутилини
OA54711A OA04192A (fr) 1971-10-05 1972-10-04 Procédé de préparation de nouveaux dérivés de la pleuromutiline.
JP9913872A JPS577147B2 (ja) 1971-10-05 1972-10-04
IL40494A IL40494A (en) 1971-10-05 1972-10-04 Pleuromutilins,their production and pharmaceutical compositions containing them
SU1835486A SU523632A3 (ru) 1971-10-05 1972-10-04 Способ получени плевромутилинов
AU47405/72A AU484191B2 (en) 1972-10-04 Pleuromutilin derivatives
BG023481A BG21386A3 (bg) 1971-10-05 1972-10-04 Метод за получаване на плевромутилини
IL4726272A IL47262A (en) 1971-10-05 1972-10-04 14-desoxy-14-((2-diethylaminoethyl)mercaptoacetoxy)-mutilin,its salts and pharmaceutical compositions containing it
CS670172A CS219306B2 (en) 1971-10-05 1972-10-04 Method of making the new pleuromutilines
YU249772A YU37125B (en) 1971-10-05 1972-10-04 Process for preparing new pleuromutilins
ZA727125A ZA727125B (en) 1971-10-05 1972-10-05 Improvements in or relating to organic compounds
DD166051A DD100706A5 (ja) 1971-10-05 1972-10-05
FR7235340A FR2157828B1 (ja) 1971-10-05 1972-10-05
NO4617/73A NO136837C (no) 1971-10-05 1973-12-04 Analogifremgangsm}te for fremstilling av terapeutisk aktive pleuromutiliner
NO4618/73A NO137440C (no) 1971-10-05 1973-12-04 Analogifremgangsmaate for fremstilling av terapeutisk aktive pleuromutiliner
US05/606,430 US4032530A (en) 1971-10-05 1975-08-21 Certain pleuromutilins
SE7509456A SE424074B (sv) 1971-10-05 1975-08-26 Forfarande for framstellning av substituerade pleuromutiliner
SE7509457A SE419984B (sv) 1971-10-05 1975-08-26 Forfarande for framstellning av nya pleuromutiliner
DK498176A DK142700B (da) 1971-10-05 1976-11-03 Analogifremgangsmåde til fremstilling af pleuromutiliner.
DK498076A DK140592B (da) 1971-10-05 1976-11-03 Analogifremgangsmåde til fremstilling af pleuromutiliner eller syreadditionssalte eller kvaternære salte deraf.
US05/758,133 US4107164A (en) 1971-10-05 1977-01-10 Certain pleuromulilin ester derivatives
US05/912,497 US4208326A (en) 1971-10-05 1978-06-05 Pleuromutilin esters
HK25379A HK25379A (en) 1971-10-05 1979-04-19 A novel pleuromutilin derivative
US06/098,333 US4278674A (en) 1971-10-05 1979-11-29 Substituted 14-desoxy-mutilin compositions
FI794061A FI60204C (fi) 1971-10-05 1979-12-27 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara pleuromutiliner
FI794060A FI60198C (fi) 1971-10-05 1979-12-27 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara pleuromutiliner
MY7900103A MY7900103A (en) 1971-10-05 1979-12-30 A novel pleuromutilin derivative
JP55152399A JPS5852994B2 (ja) 1971-10-05 1980-10-31 プルロムチリンの製法
JP15239880A JPS5695163A (en) 1971-10-05 1980-10-31 Manufacture of pleuromutilin

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1445071A CH560180A5 (en) 1971-10-05 1971-10-05 Pleuromutilin derivs - with antibacterial activity

Publications (1)

Publication Number Publication Date
CH560180A5 true CH560180A5 (en) 1975-03-27

Family

ID=4400921

Family Applications (1)

Application Number Title Priority Date Filing Date
CH1445071A CH560180A5 (en) 1971-10-05 1971-10-05 Pleuromutilin derivs - with antibacterial activity

Country Status (4)

Country Link
JP (2) JPS5852994B2 (ja)
CH (1) CH560180A5 (ja)
SU (1) SU523632A3 (ja)
ZA (1) ZA727125B (ja)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1808431A1 (en) * 2006-01-16 2007-07-18 Nabriva Therapeutics Forschungs GmbH Mutilin derivatives and their use as pharmaceutical
CN103709093B (zh) * 2012-09-28 2016-06-08 山东亨利医药科技有限责任公司 含有并环的截短侧耳素类抗生素

Also Published As

Publication number Publication date
JPS5695180A (en) 1981-08-01
AU4740572A (en) 1974-04-11
JPS5852994B2 (ja) 1983-11-26
ZA727125B (en) 1974-05-29
SU523632A3 (ru) 1976-07-30
JPS5695163A (en) 1981-08-01

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Legal Events

Date Code Title Description
PL Patent ceased