CH498834A - Verfahren zur Herstellung von laevo-1-n-Butyl-2',6'-pipecoloxylidid - Google Patents

Verfahren zur Herstellung von laevo-1-n-Butyl-2',6'-pipecoloxylidid

Info

Publication number
CH498834A
CH498834A CH733568A CH733568A CH498834A CH 498834 A CH498834 A CH 498834A CH 733568 A CH733568 A CH 733568A CH 733568 A CH733568 A CH 733568A CH 498834 A CH498834 A CH 498834A
Authority
CH
Switzerland
Prior art keywords
pipecoloxylidide
laevo
butyl
dextro
tartrate
Prior art date
Application number
CH733568A
Other languages
German (de)
English (en)
Inventor
Pindaro Luduena Froilan
Franklin Tullar Benjamin
Original Assignee
Sterling Drug Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterling Drug Inc filed Critical Sterling Drug Inc
Publication of CH498834A publication Critical patent/CH498834A/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
CH733568A 1967-05-18 1968-05-17 Verfahren zur Herstellung von laevo-1-n-Butyl-2',6'-pipecoloxylidid CH498834A (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US63927767A 1967-05-18 1967-05-18

Publications (1)

Publication Number Publication Date
CH498834A true CH498834A (de) 1970-11-15

Family

ID=24563449

Family Applications (1)

Application Number Title Priority Date Filing Date
CH733568A CH498834A (de) 1967-05-18 1968-05-17 Verfahren zur Herstellung von laevo-1-n-Butyl-2',6'-pipecoloxylidid

Country Status (13)

Country Link
AT (2) AT286298B (el)
BE (1) BE715188A (el)
CH (1) CH498834A (el)
DE (1) DE1770408C3 (el)
DK (1) DK129234B (el)
ES (1) ES354352A1 (el)
FI (1) FI50333C (el)
FR (2) FR1583872A (el)
GB (1) GB1180712A (el)
IL (1) IL29958A (el)
NL (1) NL6806995A (el)
NO (1) NO124540B (el)
SE (1) SE341404B (el)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3379266D1 (en) * 1983-08-01 1989-04-06 Astra Laekemedel Ab L-n-n-propylpipecolic acid-2,6-xylidide and method for preparing the same
SE451840B (sv) * 1986-01-03 1987-11-02 Astra Laekemedel Ab Optiskt rent monohydrat av s-(-)-1-propyl-2',6'-pipekoloxylididhydroklorid, sett att framstella denna och farmaceutiska beredningar for lokalbedovning
EP0788480B1 (en) * 1994-10-25 2003-07-23 Darwin Discovery Limited Crystallisation of levobupivacaine and analogues thereof
SE9501808D0 (sv) * 1995-05-16 1995-05-16 Astra Ab New process
KR100844336B1 (ko) * 2007-01-16 2008-07-07 하나제약 주식회사 레보부피바카인 및 이의 염산염의 신규한 제조방법
WO2014009964A1 (en) * 2012-07-11 2014-01-16 Neon Laboratories Limited Process for enantiomeric enrichment of 2 ', 6 ' - pipecoloxylidide
CN105315196A (zh) * 2015-11-28 2016-02-10 山东齐都药业有限公司 一种高纯度盐酸左布比卡因精制方法
CN109896992A (zh) * 2017-12-08 2019-06-18 武汉软件工程职业学院 制备离子液体的方法及其应用

Also Published As

Publication number Publication date
FI50333B (el) 1975-10-31
FR8160M (el) 1970-08-24
AT284843B (de) 1970-09-25
GB1180712A (en) 1970-02-11
DE1770408C3 (de) 1974-11-07
DE1770408A1 (de) 1971-10-21
SE341404B (el) 1971-12-27
IL29958A0 (en) 1968-07-25
ES354352A1 (es) 1969-11-01
FI50333C (fi) 1976-02-10
DE1770408B2 (el) 1974-04-11
DK129234B (da) 1974-09-16
DK129234C (el) 1975-02-03
NO124540B (el) 1972-05-02
IL29958A (en) 1971-04-28
AT286298B (de) 1970-12-10
NL6806995A (el) 1968-11-19
BE715188A (el) 1968-09-30
FR1583872A (el) 1969-12-05

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Legal Events

Date Code Title Description
PL Patent ceased